CN109222278A - A kind of antibacterial mask and preparation method thereof - Google Patents

A kind of antibacterial mask and preparation method thereof Download PDF

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Publication number
CN109222278A
CN109222278A CN201811206300.XA CN201811206300A CN109222278A CN 109222278 A CN109222278 A CN 109222278A CN 201811206300 A CN201811206300 A CN 201811206300A CN 109222278 A CN109222278 A CN 109222278A
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CN
China
Prior art keywords
parts
root
honeysuckle
scutellaria
rhizoma atractylodis
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CN201811206300.XA
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Chinese (zh)
Inventor
林丽嫦
林树堂
林淑琴
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Jiangmen Junhe Office Supplies Co Ltd
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Jiangmen Junhe Office Supplies Co Ltd
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Priority to CN201811206300.XA priority Critical patent/CN109222278A/en
Publication of CN109222278A publication Critical patent/CN109222278A/en
Withdrawn legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D13/00Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches
    • A41D13/05Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches protecting only a particular body part
    • A41D13/11Protective face masks, e.g. for surgical use, or for use in foul atmospheres
    • A41D13/1192Protective face masks, e.g. for surgical use, or for use in foul atmospheres with antimicrobial agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/38Silver; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics

Abstract

The invention discloses a kind of antibacterial masks and preparation method thereof, the antibacterial mask middle layer is to have adsorbed the medical woven fabric of bactericidal composition, and the bactericidal composition includes the ingredient of following parts by weight: 5~15 parts of honeysuckle, 5~10 parts of scutellaria, 5~12 parts of the root of Dahurain angelica, 8~10 parts of Fructus Forsythiae, 15~25 parts of nano silver, 5~12 parts of Rhizoma Atractylodis Macrocephalae, 10~15 parts of dried orange peel, 5~10 parts of five-leaved chaste tree, 8~15 parts of Radix Glycyrrhizae.The present invention uses honeysuckle, scutellaria, the root of Dahurain angelica, Fructus Forsythiae, Rhizoma Atractylodis Macrocephalae, dried orange peel, five-leaved chaste tree, traditional Chinese medicine of licorice root ingredient, it is compounded with nano silver, pharmacological research shows, using plurality of Chinese effective component, in the case of capable of effectively inhibiting bacterium and mould, Multiple components to compound, play the antibacterial effect of synergy, various bacteriums can effectively be inhibited, effect is obvious, has good Prevention to act on simultaneously for the mouths such as canker sore, rhinitis, disease of the nose.

Description

A kind of antibacterial mask and preparation method thereof
Technical field
The present invention relates to mask technical field, it is specifically related to a kind of antibacterial mask and preparation method thereof.
Background technique
Mask is a kind of amenities, refers generally to be worn over nose and mouth for filtering the air for entering mouth and nose, to reach resistance The apparatus for keeping off harmful gas, smell, droplet disengaging wearer's mouth and nose, is made with gauze or paper etc..Mask is to entrance lung Air has certain filtration, and in respiratory infectious disease prevalence, in the environment of the pollutions such as dust when operation, wear masks tool There is extraordinary effect.Mask can be divided into air filtering type mask and Gas feeding mask.Harmful bacteria in air is ubiquitous, Including diplococcus, monococcus, doctor sarcine, tetrads, staphylococcus etc., reproduction speed is fast, survival ability is strong, involves model Enclose wide, when propagating in air, cause many diseases, as influenza, tuberculosis, morbilli, mumps, pertussis, Diphtheria etc., they have stronger infectiousness and harmfulness.Mask on the market is the pollution for stopping dust, fog etc Object, medical mask can also be used to that bacterial virus is avoided to invade human body.Conventional mask is being resisted influenza virus, bacterium, may be inhaled In particle, effect is not so good as medical mask, but medical mask price is high, inconvenient to use, and the conventional mask in market uses Effect is bad.
Summary of the invention
A kind of antibacterial mask is provided it is an object of the invention to overcome the above problem, is used in the antibacterial mask anti- Bacteria composition, good antimicrobial effect, nontoxic advantage safe to the human body.
To achieve the above object, a kind of antibacterial mask of technical solution that the present invention takes, the antibacterial mask middle layer are The medical woven fabric of bactericidal composition is adsorbed, the bactericidal composition includes the ingredient of following parts by weight: 5~15 parts of honeysuckle, 5~10 parts of scutellaria, 5~12 parts of the root of Dahurain angelica, 8~10 parts of Fructus Forsythiae, 15~25 parts of nano silver, 5~12 parts of Rhizoma Atractylodis Macrocephalae, 10~15 parts of dried orange peel, 5~10 parts of five-leaved chaste tree, 8~15 parts of Radix Glycyrrhizae.
The effect of each traditional Chinese medicine ingredients of the invention, is as follows:
Honeysuckle: honeysuckle is that Caprifoliaceae perennial evergreen winds the bud of bejuco honeysuckle also known as honeysuckle flower, double Flower, in China in addition to northwest, northeast, other each provinces and regions are distributed.Traditional Chinese Medicine thinks that honeysuckle is cold in nature sweet in flavor, has heat-clearing The effect of removing toxic substances, wind-heat dissipating, is used for carbuncle swells furunculosis, sore throat, erysipelas, warm blood fulminant dysentery, anemopyretic cold, warm disease heating.Its chemistry Ingredient is mainly chlorogenic acid, isochlorogenic acid, aromatic alcohol, Luteolin, honeysuckle saponin(e and flavone compound.Research card at present Real honeysuckle has the effects that broad-spectrum antiseptic, antiviral, antipyretic and anti-inflammatory, lidan liver, lipid-loweringing.Some researches show that honeysuckle mentions Take object to typhoid bacillus, paratyphosum Bacterium, Escherichia coli, proteus, Pseudomonas aeruginosa, Bordetella pertussis, comma bacillus, grape Coccus, streptococcus, Diplococcus pneumopniae, meningococcus etc. have inhibiting effect.
Scutellaria: scutellaria: heat-clearing and damp-drying drug, purging fire for removing toxin, tonic blood and growing muscle, therefore effect is also widely used for beauty treatment fields: Radix scutellariae has broad-spectrum antiseptic antiallergy and antiinflammation, therefore pimples acne can also be played with the function of antiphlogistic antibacterial, is one The waste that skin metabolism generates can be removed, make skin completely smooth by the good skin street cleaner of kind.Suitable for each Kind dermatitis, comedo and acne, eczema, pimples etc., are the common medicines of therapeutic beauty.Vulgaris face acnes curative effect is reliable, tool There is the effect of clearing heat and detoxicating, removing dampness and destroying parasites.
The root of Dahurain angelica: it is acrid in flavour and warm in nature, return stomach, large intestine, lung channel;Relieve heat dehumidifying, sensible analgesic, detumescence and apocenosis.For cold headache, eyebrow Rib ostalgia, nasal obstruction, nasosinusitis, toothache, leukorrhea, sore swell and ache curative.
Fructus Forsythiae: clearing heat and detoxicating, clearing heart fire, it is kind to control face caused by sore swells, scrofula and cardiopulmonary intrinsic heat and damage capacitive disease Disease, such as acne, face spot card, compatibility is proper, can often obtain effect.
Nano silver: Nano silver solution (Nano Silver) is the metallic silver simple substance that partial size is prepared into 1-100nm.Nanometer Silver granuel diameter is mostly in 20 rans, and a small number of reachable 5 nanometers hereinafter, such as auspicious 2 ran of chem nano silver partial size of space.With light Compose bactericidal effect.
Rhizoma Atractylodis Macrocephalae: bitter, it is sweet, it is warm-natured.Returns spleen, stomach meridian.Major function: strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention.For Spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, threatened abortion.Rhizoma Atractylodis Macrocephalae invigorating the spleen, stomach function regulating, miscarriage prevention.It is eaten for spleen deficiency It is few, diarrhea loose stool, threatened abortion.
Dried orange peel: warm-natured, acrid flavour, bitter.Enter the spleen channel, stomach meridian, lung channel.Attending effectiveness: regulating qi-flowing for strengthening spleen, in tune, eliminating dampness is changed Phlegm.Cure mainly the abdominal fullness and distention or pain, indigestion of the taste stagnation of the circulation of vital energy.Abdominal distension uncomfortable in chest, anorexia and loose stool in wet turbid resistance.Phlegm obstructing lung Cough and asthma.For chest gastral cavity turgor, deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.
Five-leaved chaste tree: five-leaved chaste tree alias five-leaved chaste tree item, fruit of negundo, cloth chaste tree, the twigs of the chaste tree, the five fingers mandarin orange, the five fingers wind, fruit of negundo have cough-relieving, dispel Phlegm and the effect for alleviating bronchial spasm, cure mainly the diseases such as flu, cough, asthma, malaria, Negundo Chastetree Leaf relieving superficies by cooling, eliminating damp, detoxifying, The diseases such as flu, heatstroke, dysentery, malaria are cured mainly, fruit of negundo and negundo chastetree root decoction are equal to staphylococcus aureus and micrococcus catarrhalis There is inhibiting effect, Negundo Chastetree Leaf has suppression to staphylococcus aureus, Escherichia coli, mould and aspergillus to the stem of head mold, mould five-leaved chaste tree Effect processed.
Radix Glycyrrhizae: containing glycyrrhizin, glycyrrhizic acid, liquiritin, sweet flavonoids, rear curtain are than wingceltis element, formoononetin, Quercetin Deng, it is yellow to brown color liquid, Licorice flavanone belongs to the derivative of phenolic compound, and it is weakly acidic, protein coagulating can be made Or denaturation, microbial cell can be caused to discharge ingredient intracellular, the electronics of film is caused to pass by the integrality of cell wall or cell membrane It passs, nutrient absorption, the dysfunctions such as nucleotide synthesis and ATP activity, to inhibit the development of microorganism, it is to golden yellow Portugal Grape coccus, large intestine Ai Xishi bacillus, Pseudomonas aeruginosa, Escherichia coli, mould have apparent inhibitory effect;Glycyrrhizic acid has relatively strong Antiviral, bacteriostasis, have to staphylococcus aureus, large intestine Ai Xishi bacillus, Pseudomonas aeruginosa etc. and preferable inhibit effect Fruit;Licorice polysaccharide not only has immunization, also has fungistatic effect;Radix Glycyrrhizae and some drugs are shared with synergistic effect, Compatibe drug effective component dissolubility can be made to increase, enhance fungistatic effect by solubilising.
The present invention uses honeysuckle, scutellaria, the root of Dahurain angelica, Fructus Forsythiae, Rhizoma Atractylodis Macrocephalae, dried orange peel, five-leaved chaste tree, traditional Chinese medicine of licorice root ingredient, with nano silver Compounding, pharmacological research show effectively inhibit bacterium and mould, Multiple components are multiple using yellow plurality of Chinese effective component In the case of matching, the antibacterial effect of synergy is played, effect is significantly better than an individually addition wherein ingredient, or components matching two-by-two.
Preferably, the bactericidal composition includes the ingredient of following parts by weight: 10~13 parts of honeysuckle, 6~8 parts of scutellaria, 8~10 parts of the root of Dahurain angelica, 8~9 parts of Fructus Forsythiae, 18~22 parts of nano silver, 8~10 parts of Rhizoma Atractylodis Macrocephalae, 10~13.5 parts of dried orange peel, 6~8 parts of five-leaved chaste tree, 10~12 parts of Radix Glycyrrhizae.
Preferably, the bactericidal composition includes the ingredient of following parts by weight: 10 parts of honeysuckle, 6 parts of scutellaria, 8 parts of the root of Dahurain angelica, 8 parts of Fructus Forsythiae, 20 parts of nano silver, 8 parts of Rhizoma Atractylodis Macrocephalae, 12 parts of dried orange peel, 7.5 parts of five-leaved chaste tree, 10 parts of Radix Glycyrrhizae.
Preferably, the bactericidal composition includes the ingredient of following parts by weight: 12 parts of honeysuckle, 8 parts of scutellaria, the root of Dahurain angelica 10 Part, 9 parts of Fructus Forsythiae, 18 parts of nano silver, 8 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of dried orange peel, 6 parts of five-leaved chaste tree, 12 parts of Radix Glycyrrhizae.
Preferably, the bactericidal composition includes the ingredient of following parts by weight: 13 parts of honeysuckle, 7.5 parts of scutellaria, the root of Dahurain angelica 10 Part, 9 parts of Fructus Forsythiae, 22 parts of nano silver, 10 parts of Rhizoma Atractylodis Macrocephalae, 13.5 parts of dried orange peel, 8 parts of five-leaved chaste tree, 13 parts of Radix Glycyrrhizae.
Preferably, the bactericidal composition includes the ingredient of following parts by weight: 13.5 parts of honeysuckle, 10 parts of scutellaria, the root of Dahurain angelica 12 parts, 10 parts of Fructus Forsythiae, 20 parts of nano silver, 10 parts of Rhizoma Atractylodis Macrocephalae, 13 parts of dried orange peel, 8 parts of five-leaved chaste tree, 12 parts of Radix Glycyrrhizae.
Preferably, the bactericidal composition includes the ingredient of following parts by weight: 15 parts of honeysuckle, 8.5 parts of scutellaria, the root of Dahurain angelica 10 Part, 9.5 parts of Fructus Forsythiae, 25 parts of nano silver, 12 parts of Rhizoma Atractylodis Macrocephalae, 15 parts of dried orange peel, 10 parts of five-leaved chaste tree, 15 parts of Radix Glycyrrhizae.
The present invention also provides a kind of preparation methods of antibacterial mask: the following steps are included: 1) extracting honeysuckle, scutellaria, white The root of Dahurian angelica, Fructus Forsythiae, Rhizoma Atractylodis Macrocephalae, dried orange peel, five-leaved chaste tree, Radix Glycyrrhizae various Chinese medicines crush after mix, be added 9 times of volume of water, impregnate 65min, decoct 2h is filtered under diminished pressure, and filtrate is spare;
2) 8 times of volume of water are added in the dregs of a decoction obtained by step (1), decoct 100min, is filtered under diminished pressure, filtrate is spare;
3) filtrate obtained by step 1) and step 2) is merged, crosses 400 meshes, filtrate is concentrated to relatively close 1.0~1.5, adds Enter nano silver, be dissolved in glycerine by 1:2, ultrasonic disperse is uniform, place into the middle layer cotton gauze that mask uses impregnate two hours with On.
Beneficial effects of the present invention: the present invention uses honeysuckle, scutellaria, the root of Dahurain angelica, Fructus Forsythiae, Rhizoma Atractylodis Macrocephalae, dried orange peel, five-leaved chaste tree, Radix Glycyrrhizae Traditional Chinese medicine ingredients are compounded with nano silver, and pharmacological research shows effectively inhibit bacterium using yellow plurality of Chinese effective component And mould, in the case of Multiple components compound, the antibacterial effect of synergy is played, effect is significantly better than individually wherein one one-tenth of addition Point, or components matching two-by-two.The present invention is prepared into antibacterial mask, can prevent PM2.5 particle and significant antibacterial, can use In general population, it is also applied to medical mask, is had a wide range of application;Bactericidal composition prepared by the present invention, by nano silver and Traditional Chinese medicine bacteriostatic ingredient combines, and preparation is simple, can effectively inhibit various bacteriums, effect is obvious, simultaneously for canker sore, rhinitis Equal mouths, disease of the nose have good Prevention to act on.
Specific embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention It is described further.
Embodiment 1
As a kind of embodiment of antibacterial mask of the invention, the antibacterial mask middle layer is to have adsorbed bactericidal composition Medical woven fabric, the bactericidal composition includes the ingredient of following parts by weight: 10 parts of honeysuckle, 6 parts of scutellaria, 8 parts of the root of Dahurain angelica, Fructus Forsythiae 8 parts, 20 parts of nano silver, 8 parts of Rhizoma Atractylodis Macrocephalae, 12 parts of dried orange peel, 7.5 parts of five-leaved chaste tree, 10 parts of Radix Glycyrrhizae.
The preparation method of the antibacterial mask: 1) extracting honeysuckle, scutellaria, the root of Dahurain angelica, Fructus Forsythiae, Rhizoma Atractylodis Macrocephalae, dried orange peel, five-leaved chaste tree, Radix Glycyrrhizae Various Chinese medicines mix after crushing, and 9 times of volume of water are added, and impregnate 65min, decoct 2h, are filtered under diminished pressure, filtrate is spare;
2) 8 times of volume of water are added in the dregs of a decoction obtained by step (1), decoct 100min, is filtered under diminished pressure, filtrate is spare;
3) filtrate obtained by step 1) and step 2) is merged, crosses 400 meshes, filtrate is concentrated to relatively close 1.0~1.5, adds Enter nano silver, be dissolved in glycerine by 1:2, ultrasonic disperse is uniform, place into the middle layer cotton gauze that mask uses impregnate two hours with On.
Embodiment 2
As a kind of embodiment of antibacterial mask of the invention, the antibacterial mask middle layer is to have adsorbed bactericidal composition Medical woven fabric, the bactericidal composition includes the ingredient of following parts by weight: 5 parts of honeysuckle, 6 parts of scutellaria, 5 parts of the root of Dahurain angelica, Fructus Forsythiae 8.5 parts, 18 parts of nano silver, 5 parts of Rhizoma Atractylodis Macrocephalae, 12 parts of dried orange peel, 5 parts of five-leaved chaste tree, 8 parts of Radix Glycyrrhizae.The preparation method of the present embodiment antibacterial mask It is same as Example 1.
Embodiment 3
As a kind of embodiment of antibacterial mask of the invention, the antibacterial mask middle layer is to have adsorbed bactericidal composition Medical woven fabric, the bactericidal composition includes the ingredient of following parts by weight: 12 parts of honeysuckle, 8 parts of scutellaria, 10 parts of the root of Dahurain angelica, even Stick up 9 parts, 18 parts of nano silver, 8 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of dried orange peel, 6 parts of five-leaved chaste tree, 12 parts of Radix Glycyrrhizae.The preparation method of the present embodiment antibacterial mask It is same as Example 1.
Embodiment 4
As a kind of embodiment of antibacterial mask of the invention, the antibacterial mask middle layer is to have adsorbed bactericidal composition Medical woven fabric, the bactericidal composition includes the ingredient of following parts by weight: 13 parts of honeysuckle, 7.5 parts of scutellaria, 10 parts of the root of Dahurain angelica, 9 parts of Fructus Forsythiae, 22 parts of nano silver, 10 parts of Rhizoma Atractylodis Macrocephalae, 13.5 parts of dried orange peel, 8 parts of five-leaved chaste tree, 13 parts of Radix Glycyrrhizae.The system of the present embodiment antibacterial mask Preparation Method is same as Example 1.
Embodiment 5
As a kind of embodiment of antibacterial mask of the invention, the antibacterial mask middle layer is to have adsorbed bactericidal composition Medical woven fabric, the bactericidal composition includes the ingredient of following parts by weight: 13.5 parts of honeysuckle, 10 parts of scutellaria, 12 parts of the root of Dahurain angelica, 10 parts of Fructus Forsythiae, 20 parts of nano silver, 10 parts of Rhizoma Atractylodis Macrocephalae, 13 parts of dried orange peel, 8 parts of five-leaved chaste tree, 12 parts of Radix Glycyrrhizae.The preparation of the present embodiment antibacterial mask Method is same as Example 1.
Embodiment 6
As a kind of embodiment of antibacterial mask of the invention, the antibacterial mask middle layer is to have adsorbed bactericidal composition Medical woven fabric, the bactericidal composition includes the ingredient of following parts by weight: 15 parts of honeysuckle, 8.5 parts of scutellaria, 10 parts of the root of Dahurain angelica, 9.5 parts of Fructus Forsythiae, 25 parts of nano silver, 12 parts of Rhizoma Atractylodis Macrocephalae, 15 parts of dried orange peel, 10 parts of five-leaved chaste tree, 15 parts of Radix Glycyrrhizae.The system of the present embodiment antibacterial mask Preparation Method is same as Example 1.
Comparative example 1
The antibacterial mask difference from Example 1 of this comparative example is that bactericidal composition includes following parts by weight Ingredient: 8 parts of the root of Dahurain angelica, 8 parts of Fructus Forsythiae, 20 parts of nano silver, 8 parts of Rhizoma Atractylodis Macrocephalae, 12 parts of dried orange peel, 7.5 parts of five-leaved chaste tree, 10 parts of Radix Glycyrrhizae.This comparative example The preparation method of antibacterial mask is same as Example 1.
Comparative example 2
The antibacterial mask difference from Example 1 of this comparative example is that bactericidal composition includes following parts by weight Ingredient: 10 parts of honeysuckle, 6 parts of scutellaria, 20 parts of nano silver, 12 parts of dried orange peel, 7.5 parts of five-leaved chaste tree, 10 parts of Radix Glycyrrhizae.This comparative example antibacterial mouth The preparation method of cover is same as Example 1.
Comparative example 3
The antibacterial mask difference from Example 1 of this comparative example is that bactericidal composition includes following parts by weight Ingredient: 2 parts of honeysuckle, 2 parts of scutellaria, 15 parts of the root of Dahurain angelica, 5 parts of Fructus Forsythiae, 20 parts of nano silver, 8 parts of Rhizoma Atractylodis Macrocephalae, 12 parts of dried orange peel, five-leaved chaste tree 7.5 Part, 10 parts of Radix Glycyrrhizae.
7 bacteriostatic test of embodiment
(1) bacteriostatic experiment
1, for trying strain: Escherichia coli, staphylococcus aureus, bacillus subtilis and Candida albicans are all from Guangzhou Institute of microbiology.
2, culture medium: Escherichia coli, staphylococcus aureus, bacillus subtilis and Candida albicans nutrient agar: Peptone 10g, beef extract 3g, NaCl 5g, agar 15g, glucose 5g and water 1000mL, pH value 7;The above culture medium exists 0.1MPa, 121.3 DEG C, sterilize 20min.
3, bacteria suspension must be prepared
By it is each for examination bacterium activate on respective culture medium after, respectively with sterile saline be configured to containing bacterium number be 106 ~107The bacteria suspension of a/mL is spare, generally selects bacterium colony 2 to be of moderate size, and 9mL sterile saline is added in sterile working In, mix.
4, measuring method: in culture medium flat plate center, note puts the bacteria inhibiting composition through embodiment 1 to 6 and comparative example 1~3 The filter paper dick of processing is cultivated at a temperature of respectively suitable.Bacteria inhibiting composition in filter paper is through that can form to infiltration of ambient Inhibition zone.Measure the size of antibacterial circle diameter, it can be determined that go out the effect of bacteria inhibiting composition.Antibacterial circle diameter is bigger, shows to press down The effect of bacteria composition is better.1"3,4,5,6,2
The fungistatic effect of 1 Examples 1 to 6 of table and 1~3 bacteria inhibiting composition of comparative example compares
From the result in the Examples 1 to 6 in table 1 it is found that bacteria inhibiting composition of the invention, the diameter of inhibition zone are all larger than Comparative example, wherein more excellent with 1,3,4 effect of embodiment, especially 1 effect of embodiment is best.
The ingredient of the bacteria inhibiting composition of comparative example 1~2 lacks honeysuckle, scutellaria ingredient and white compared to embodiment 1 respectively The root of Dahurian angelica, Fructus Forsythiae and Rhizoma Atractylodis Macrocephalae, it can be seen that its it is antibacterial compared with of the invention there is also difference, illustrate that composition of the invention need to be a variety of Under ingredient collective effect, it can just reach significant fungistatic effect.
Comparative example 3 is to use identical composition, and the weight of formulation section ingredient is in specific ratio of the invention Outside range, effect is nothing like effect of the invention, it was demonstrated that, composition of the invention could be sent out only in special ratios Wave significant fungistatic effect.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention Within mind and principle, any modification, equivalent substitution, improvement and etc. done be should be included within the scope of the present invention.

Claims (8)

1. a kind of antibacterial mask, which is characterized in that the antibacterial mask middle layer is to have adsorbed the medical woven fabric of bactericidal composition, The bactericidal composition includes the ingredient of following parts by weight: 5~15 parts of honeysuckle, 5~10 parts of scutellaria, 5~12 parts of the root of Dahurain angelica, Fructus Forsythiae 8~10 parts, 15~25 parts of nano silver, 5~12 parts of Rhizoma Atractylodis Macrocephalae, 10~15 parts of dried orange peel, 5~10 parts of five-leaved chaste tree, 8~15 parts of Radix Glycyrrhizae.
2. antibacterial mask according to claim 1, which is characterized in that the bactericidal composition include following parts by weight at Point: 10~13 parts of honeysuckle, 6~8 parts of scutellaria, 8~10 parts of the root of Dahurain angelica, 8~9 parts of Fructus Forsythiae, 18~22 parts of nano silver, Rhizoma Atractylodis Macrocephalae 8~10 Part, 10~13.5 parts of dried orange peel, 6~8 parts of five-leaved chaste tree, 10~12 parts of Radix Glycyrrhizae.
3. antibacterial mask according to claim 1, which is characterized in that the bactericidal composition include following parts by weight at Point: 10 parts of honeysuckle, 6 parts of scutellaria, 8 parts of the root of Dahurain angelica, 8 parts of Fructus Forsythiae, 20 parts of nano silver, 8 parts of Rhizoma Atractylodis Macrocephalae, 12 parts of dried orange peel, 7.5 parts of five-leaved chaste tree, 10 parts of Radix Glycyrrhizae.
4. antibacterial mask according to claim 1, which is characterized in that the bactericidal composition include following parts by weight at Point: it is 12 parts of honeysuckle, 8 parts of scutellaria, 10 parts of the root of Dahurain angelica, 9 parts of Fructus Forsythiae, 18 parts of nano silver, 8 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of dried orange peel, 6 parts of five-leaved chaste tree, sweet 12 parts of grass.
5. antibacterial mask according to claim 1, which is characterized in that the bactericidal composition include following parts by weight at Point: 13 parts of honeysuckle, 7.5 parts of scutellaria, 10 parts of the root of Dahurain angelica, 9 parts of Fructus Forsythiae, 22 parts of nano silver, 10 parts of Rhizoma Atractylodis Macrocephalae, 13.5 parts of dried orange peel, five-leaved chaste tree 8 Part, 13 parts of Radix Glycyrrhizae.
6. antibacterial mask according to claim 1, which is characterized in that the bactericidal composition include following parts by weight at Point: 13.5 parts of honeysuckle, 10 parts of scutellaria, 12 parts of the root of Dahurain angelica, 10 parts of Fructus Forsythiae, 20 parts of nano silver, 10 parts of Rhizoma Atractylodis Macrocephalae, 13 parts of dried orange peel, five-leaved chaste tree 8 Part, 12 parts of Radix Glycyrrhizae.
7. antibacterial mask according to claim 1, which is characterized in that the bactericidal composition include following parts by weight at Point: 15 parts of honeysuckle, 8.5 parts of scutellaria, 10 parts of the root of Dahurain angelica, 9.5 parts of Fructus Forsythiae, 25 parts of nano silver, 12 parts of Rhizoma Atractylodis Macrocephalae, 15 parts of dried orange peel, five-leaved chaste tree 10 parts, 15 parts of Radix Glycyrrhizae.
8. a kind of preparation method of antibacterial mask as described in any one of claim 1 to 7: it is characterised in that it includes following step It is rapid: 1) extracting honeysuckle, scutellaria, the root of Dahurain angelica, Fructus Forsythiae, Rhizoma Atractylodis Macrocephalae, dried orange peel, five-leaved chaste tree, Radix Glycyrrhizae various Chinese medicines crush after mix, be added 9 times Volume of water impregnates 65min, decocts 2h, is filtered under diminished pressure, filtrate is spare;
2) 8 times of volume of water are added in the dregs of a decoction obtained by step (1), decoct 100min, is filtered under diminished pressure, filtrate is spare;
3) filtrate obtained by step 1) and step 2) is merged, crosses 400 meshes, filtrate is concentrated to relatively close 1.0~1.5, addition is received Meter Yin is dissolved in glycerine by 1:2, and ultrasonic disperse is uniform, places into the immersion of middle layer cotton gauze two hours or more that mask uses.
CN201811206300.XA 2018-10-16 2018-10-16 A kind of antibacterial mask and preparation method thereof Withdrawn CN109222278A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109619727A (en) * 2019-01-30 2019-04-16 哈工大机器人(山东)智能装备研究院 A kind of production method for the haze mask preventing respiratory disease
CN111345288A (en) * 2020-03-12 2020-06-30 优仕康生(天津)科技发展有限公司 A colloidal carrier capable of forming antibacterial and antiviral coating on the surface of respiratory protector, colloidal tincture and application thereof
CN111466639A (en) * 2020-05-06 2020-07-31 佳木斯大学 Sustained-release medicine antiviral mask patch and preparation method thereof
CN111759030A (en) * 2020-07-01 2020-10-13 金华长弓清洁用品有限公司 Cool mask
CN113462028A (en) * 2021-07-02 2021-10-01 科迈特新材料有限公司 Nano antibacterial agent for plastics and preparation method thereof
CN114468416A (en) * 2020-10-23 2022-05-13 亿利新材料有限公司 Prevent antibacterial cool type gauze mask of haze

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109619727A (en) * 2019-01-30 2019-04-16 哈工大机器人(山东)智能装备研究院 A kind of production method for the haze mask preventing respiratory disease
CN111345288A (en) * 2020-03-12 2020-06-30 优仕康生(天津)科技发展有限公司 A colloidal carrier capable of forming antibacterial and antiviral coating on the surface of respiratory protector, colloidal tincture and application thereof
CN111466639A (en) * 2020-05-06 2020-07-31 佳木斯大学 Sustained-release medicine antiviral mask patch and preparation method thereof
CN111759030A (en) * 2020-07-01 2020-10-13 金华长弓清洁用品有限公司 Cool mask
CN114468416A (en) * 2020-10-23 2022-05-13 亿利新材料有限公司 Prevent antibacterial cool type gauze mask of haze
CN113462028A (en) * 2021-07-02 2021-10-01 科迈特新材料有限公司 Nano antibacterial agent for plastics and preparation method thereof

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