CN109200242A - It is a kind of cream health patch and preparation method thereof - Google Patents
It is a kind of cream health patch and preparation method thereof Download PDFInfo
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- CN109200242A CN109200242A CN201811091907.8A CN201811091907A CN109200242A CN 109200242 A CN109200242 A CN 109200242A CN 201811091907 A CN201811091907 A CN 201811091907A CN 109200242 A CN109200242 A CN 109200242A
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- precoat
- layer
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- gluing oxidant
- ion
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/89—Cyperaceae (Sedge family)
- A61K36/8905—Cyperus (flatsedge)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/10—Applying static electricity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
Abstract
The invention discloses a kind of newborn health patches and preparation method thereof, by precoat, it is coated on above precoat and has gluing oxidant layer, is placed on gluing oxidant layer and coverage area is less than the ion stack layer of gluing oxidant layer and is placed on ion stack layer and shape size and the identical peeling layer of precoat are constituted, wherein precoat is woven by banana fiber, bamboo charcoal fiber and far IR fibre using two-wire weaving, and precoat is adsorbed with active medicine liquid ingredient.The present invention is under the synergistic effect of precoat and ion stack layer, activating microcirculation and removing stasis medicinal, anti-inflammatory, swelling and pain relieving, warming channel and expelling cold effect, make the proliferation of mammary gland and its is effectively inhibited to women bring pain, the two-wire weaving that precoat uses simultaneously reduces braiding gap, effectively inhibits the loss of ion accumulation layer charge, to keep the curative effect of prevention and treatment of the product to the proliferation of mammary gland more lasting, the cost of patient is saved.
Description
Technical field
The present invention relates to medical supplies technical fields, specifically comprising a kind of newborn health patch and preparation method thereof.
Background technique
Newborn pain can be described as the thing that woman is subjected to a lifetime, and normal cream pain only can cause slight pain, not
It is disease, but if it is pathologic cream pain, and discover not in time, it is possible to delay diagnosis, aggravates disease.The proliferation of mammary gland
It is exactly a kind of most common pathologic cream pain, essence refers to breast epithelium and proliferation of fibrous tissue, breast tissue conduit and cream
The growth of retrogression pathological changes and progressive connective tissue of the leaflet in structure, pathogenic factor is mainly due to endocrine hormone
Imbalance.Cyclomastopathy is the most common breast disease of women, and disease incidence accounts for the first place of mammary gland disease.The disease was sent out in recent years
Sick rate shows an increasing trend year by year, and the age also increasingly becomes younger.There are about 70%~80% women to have in various degree according to investigations
The proliferation of mammary gland, be more common in 25~45 years old women, such as treat not in time, have the danger that potential breast cancer occurs.
Treatment to the proliferation of mammary gland, Chinese medicine is generally oral or is applied with the Chinese medicine of some dispersing stagnated hepatoqis, activating microcirculation and removing stasis medicinal;Doctor trained in Western medicine
Then select hormone medicine or operative treatment.The effect of this disease of Chinese traditional treatment is preferable, but Chinese medicine oral medication is numerous due to decocting medicinal herbs
Trivial, administration time is long, and patient is difficult to adhere to, the curative effect of this disease of western medical treatment is unobvious, and side effect is big.Either Chinese medicine is still
Doctor trained in Western medicine, patient will frequently enter and leave hospital and daily frequent medication, waste a large amount of time and efforts, and bring to patient
The pain of body and mind.If the method for preventing and treating the proliferation of mammary gland can be extended through in the daily nursing of women, to reach prevention and treatment cream
The purpose of gland hyperplasia, just not only can be inconvenient and painful to patient's bring to avoid traditional treatment method, has also complied at present
Inner disease outer treat and treatment medicine turn to the development trend of prevention and physical-fitness medicine.Currently, about the prevention and treatment proliferation of mammary gland
Report in terms of brassiere, but its effect is not satisfactory, cannot eliminate patient's pain root is also unable to satisfy the prevention or treatment of people
Demand.
Summary of the invention
The purpose of the present invention is to solve deficiency of the product in terms of preventing and treating female mammary gland proliferation, and provide one
Kind it can ease pain, imbibition, the newborn health patch of activating microcirculation and removing stasis medicinal and preparation method thereof.
To achieve the goals above, technical solution provided by the invention are as follows:
It is a kind of cream health patch, by precoat, the gluing oxidant layer being coated on above the precoat, be placed on the gluing oxidant layer and
Coverage area be less than the gluing oxidant layer ion stack layer and be placed on the ion stack layer and shape size with it is described
The identical peeling layer of precoat is constituted, and the peeling layer is glossy face tray paper layer.
The preparation method of the cream health patch, includes the following steps:
(1) production of precoat: precoat by banana fiber, bamboo charcoal fiber and far IR fibre using two-wire weaving weave and
At.
(2) load of medical fluid: the precoat being impregnated in active medical fluid, is supported on medicine liquid ingredient on precoat,
And quality of liquid medicine accounts for the 2% ~ 10% of precoat gross mass.
(3) production of ion stack layer: the ion stack layer is the composite charged film by polytetrafluoroethylene (PTFE) using medium
Puncture device charging is formed by certain 60~120s of charging voltage charging.
(4) precoat, gluing oxidant layer, ion stack layer and peeling layer are successively closely connected in order, and after being packaged
Finished product can be formed.
Further, in the active medicine liquid ingredient each component parts by weight are as follows: 40 ~ 60 parts of jojoba seed oil, fourth
10 ~ 20 parts of glycol, 5 ~ 10 parts of olibanum, 1 ~ 10 part of peach kernel, 2 ~ 8 parts of RADIX CURCUMAE, 7 ~ 13 parts of rhizoma cyperi, 2 ~ 6 parts of rhizome of chuanxiong, Transdermal absorption promote
Into 2 ~ 5 parts of agent, concocting method is as follows:
(1) jojoba seed oil 40 ~ 60%, butanediol 7 ~ 10% are added in ingredients pot, are heated to 80-90 DEG C, speed of agitator 35r/
Min keeps the temperature 30 minutes;
(2) 55 DEG C are cooled to, the olibanum stirred evenly, rhizoma cyperi, rhizome of chuanxiong, peach kernel, RADIX CURCUMAE is added, opens stirring, mixing speed
Skin penetration enhancer is added in 30r/min, stirring after sixty minutes, and continuation is down to after mixing evenly to be stored at room temperature.
Further, the cutaneous permeable agent is azone, in oleic acid, N- methyl -2-Pyrrolidone, propylene glycol, borneol
Any one.
Further, the weight ratio of banana fiber, bamboo charcoal fiber and far IR fibre is 1:2 in the precoat:
3。
In active medical fluid, olibanum energy regulating qi and activating blood, is chased after poison analgesic therapy;Rhizoma cyperi energy regulating the flow of vital energy and dispeling melancholy, menstruction regulating and pain relieving, are effectively relieved
Stagnation of QI due to depression of the liver, chest, the side of body, abdominal distention, swollen breasts, irregular menstruation, amenorrhea and algomenorrhea;The activating microcirculation and removing stasis medicinal of rhizome of chuanxiong energy, wind-expelling pain-stopping, have
Effect alleviates hypochondriac pain, liver blood stasis, the accumulation lump in the abdomen, pricking pain in the chest of stagnation of QI due to depression of the liver;Peach kernel have promoting blood circulation, relax bowel and defecation, only
The effect of cloperastine is breathed heavily;There is RADIX CURCUMAE the function of promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral to have preferably to the intervention and adjustment of married woman's emotional disorder
Effect.
The composite charged film of the polytetrafluoroethylene (PTFE) of ion accumulation, the charge of storage-stable are carried out using dielectric breakdown device
The high-voltage electrostatic field that can produce localized sustained, makes affected part bone, and phase occurs for the electrolyte of muscle, blood vessel, nerve, the tissues such as joint
The polarization answered, diseased region Ion transfer, active cell, repair cell tissue, so as to improve the pain symptom of diseased region.It produces
Raw low-grade fever effect, is stimulated by the receptor of human skin tissue, causes blood vessel dilatation reflexively, improves micro- follow
Ring reinforces metabolism, enhances the vigor of body cell, plays the role of activating microcirculation and removing stasis medicinal, anti-inflammatory, swelling and pain relieving, warming channel and expelling cold.It is logical
Cross meridian point effect, adjust nervus vasculairs function, follow network propagated sensation degrading the channel, the operation of exciting human meridian qi and blood, qi-regulating by the stasis of blood,
The effect of channels sootheing and network vessel quickening, adjusts body yin-yang actual situation balance.
The present invention can produce it is following the utility model has the advantages that
(1) the invention in newborn health patch is provided with precoat, on the one hand, banana fiber and bamboo charcoal fiber have certain
Suction-operated, can absorb due to application after skin surface generate sweat, keep patient more comfortable;On the other hand, far infrared
Fiber has the function of deodorization and sterilization, improves myocardial function, boosts metabolism, enhancing human body disease resistance, and patient is using more
Add sanitation and hygiene.
(2) containing active medical fluid in fabric of the present invention, composition is pure plant essence product, is applied to breast surface
When skin, it can significantly play the role of activating microcirculation and removing stasis medicinal, pain of releiving under the action of skin penetration enhancer.
(3) ion stack layer of the present invention generates the original of biologic effect using high-voltage electrostatic field and micro-current to human body
Reason directly acts on affected part by electrostatic ionic induction, the normal life for effectively inhibiting abnormal cell growth, activating benign cell
It is long, it works in the electrostatic field of particular polarity and intensity, makes the dielectric hair of the tissues such as meat at breast, blood vessel, neural joint
Raw polarization, improves microcirculation, to thoroughly eliminate deep tissue adhesion, and generates the effect cooperateed with precoat, effectively
Release breast pain.Also, due to using two-wire weaving in precoat, braiding gap is reduced, ion is effectively inhibited
The loss of accumulation layer charge saves patient's to keep the curative effect of prevention and treatment of the product to the proliferation of mammary gland more lasting
Cost.
Specific embodiment
The present invention is described further below with reference to embodiment;Following embodiment is only used for clearly illustrating this hair
Bright objects, technical solutions and advantages can not be limited the scope of the invention with this.
Embodiment 1:
A kind of cream health patch by precoat, is coated on above precoat and has gluing oxidant layer, is placed on gluing oxidant layer and coverage area
Less than the ion stack layer of gluing oxidant layer and it is placed on ion stack layer and shape size peeling layer structure identical with precoat
At peeling layer is glossy face tray paper.The product it is specific the preparation method is as follows:
(1) production of precoat: use two-wire weaving by banana fiber, bamboo charcoal fiber and far IR fibre ratio by weight for
1:2:3 is woven into fabric.
(2) allotment of active medical fluid: each medicine liquid ingredient: 40 parts of jojoba seed oil, fourth two 1) is weighed by following parts by weight
15 parts of alcohol, 5 parts of olibanum, 4 parts of peach kernel, 8 parts of RADIX CURCUMAE, 13 parts of rhizoma cyperi, 2 parts of rhizome of chuanxiong, 2 parts of azone;2) by jojoba seed oil 60%,
Butanediol 7% is added in ingredients pot, is heated to 85 DEG C, speed of agitator 35r/min, keeps the temperature 30 minutes;3) 55 DEG C are cooled to, is added
Olibanum, rhizoma cyperi, rhizome of chuanxiong, peach kernel, the RADIX CURCUMAE stirred evenly, opens stirring, mixing speed 30r/min, and stirring adds after sixty minutes
Enter azone, continuation is down to after mixing evenly to be stored at room temperature.
(3) load of medical fluid: precoat is impregnated in active medical fluid, is supported on medicine liquid ingredient on fabric, and medical fluid
Quality accounts for the 2% of gross mass.
(4) production of ion stack layer: the composite charged film of polytetrafluoroethylene (PTFE) is charged using dielectric breakdown device, passes through one
Fixed charging voltage charging 90s.
(5) precoat, gluing oxidant layer, ion stack layer and peeling layer are successively closely connected in order, and after being packaged
Finished product can be formed.
Embodiment 2:
A kind of cream health patch by precoat, is coated on above precoat and has gluing oxidant layer, is placed on gluing oxidant layer and coverage area
Less than the ion stack layer of gluing oxidant layer and it is placed on ion stack layer and shape size peeling layer structure identical with precoat
At peeling layer is glossy face tray paper.The product it is specific the preparation method is as follows:
(1) production of precoat: use two-wire weaving by banana fiber, bamboo charcoal fiber and far IR fibre ratio by weight for
1:2:3 is woven into fabric.
(2) allotment of active medical fluid: each medicine liquid ingredient: 60 parts of jojoba seed oil, fourth two 1) is weighed by following parts by weight
18 parts of alcohol, 6 parts of olibanum, 1 part of peach kernel, 6 parts of RADIX CURCUMAE, 12 parts of rhizoma cyperi, 4 parts of rhizome of chuanxiong, 5 parts of oleic acid;2) by jojoba seed oil 50%,
Butanediol 9% is added in ingredients pot, is heated to 80 DEG C, speed of agitator 35r/min, keeps the temperature 30 minutes;3) 55 DEG C are cooled to, is added
Olibanum, rhizoma cyperi, rhizome of chuanxiong, peach kernel, the RADIX CURCUMAE stirred evenly, opens stirring, mixing speed 30r/min, and stirring adds after sixty minutes
Enter oleic acid, continuation is down to after mixing evenly to be stored at room temperature.
(3) load of medical fluid: precoat is impregnated in active medical fluid, is supported on medicine liquid ingredient on fabric, and medical fluid
Quality accounts for the 8% of gross mass.
(4) production of ion stack layer: the composite charged film of polytetrafluoroethylene (PTFE) is charged using dielectric breakdown device, passes through one
Fixed charging voltage charging 60s.
(5) precoat, gluing oxidant layer, ion stack layer and peeling layer are successively closely connected in order, and after being packaged
Finished product can be formed.
Embodiment 3:
A kind of cream health patch by precoat, is coated on above precoat and has gluing oxidant layer, is placed on gluing oxidant layer and coverage area
Less than the ion stack layer of gluing oxidant layer and it is placed on ion stack layer and shape size peeling layer structure identical with precoat
At peeling layer is glossy face tray paper.The product it is specific the preparation method is as follows:
(1) production of precoat: use two-wire weaving by banana fiber, bamboo charcoal fiber and far IR fibre ratio by weight for
1:2:3 is woven into fabric.
(2) allotment of active medical fluid: each medicine liquid ingredient: 50 parts of jojoba seed oil, fourth two 1) is weighed by following parts by weight
10 parts of alcohol, 10 parts of olibanum, 10 parts of peach kernel, 2 parts of RADIX CURCUMAE, 7 parts of rhizoma cyperi, 5 parts of rhizome of chuanxiong, 4 parts of propylene glycol;2) by jojoba seed oil
45%, butanediol 8% is added in ingredients pot, is heated to 88 DEG C, speed of agitator 35r/min, keeps the temperature 30 minutes;3) 55 DEG C are cooled to,
Olibanum, rhizoma cyperi, rhizome of chuanxiong, peach kernel, the RADIX CURCUMAE stirred evenly is added, opens stirring, mixing speed 30r/min is stirred 60 minutes
After be added propylene glycol, continuation is down to after mixing evenly to be stored at room temperature.
(3) load of medical fluid: precoat is impregnated in active medical fluid, is supported on medicine liquid ingredient on fabric, and medical fluid
Quality accounts for the 6% of gross mass.
(4) production of ion stack layer: the composite charged film of polytetrafluoroethylene (PTFE) is charged using dielectric breakdown device, passes through one
Fixed charging voltage charging 120s.
(5) precoat, gluing oxidant layer, ion stack layer and peeling layer are successively closely connected in order, and after being packaged
Finished product can be formed.
Embodiment 4:
A kind of cream health patch by precoat, is coated on above precoat and has gluing oxidant layer, is placed on gluing oxidant layer and coverage area
Less than the ion stack layer of gluing oxidant layer and it is placed on ion stack layer and shape size peeling layer structure identical with precoat
At peeling layer is glossy face tray paper.The product it is specific the preparation method is as follows:
(1) production of precoat: use two-wire weaving by banana fiber, bamboo charcoal fiber and far IR fibre ratio by weight for
1:2:3 is woven into fabric.
(2) allotment of active medical fluid: each medicine liquid ingredient: 55 parts of jojoba seed oil, fourth two 1) is weighed by following parts by weight
20 parts of alcohol, 8 parts of olibanum, 8 parts of peach kernel, 4 parts of RADIX CURCUMAE, 10 parts of rhizoma cyperi, 6 parts of rhizome of chuanxiong, 3 parts of borneol;2) by jojoba seed oil 40%,
Butanediol 10% is added in ingredients pot, is heated to 90 DEG C, speed of agitator 35r/min, keeps the temperature 30 minutes;3) 55 DEG C are cooled to, is added
Olibanum, rhizoma cyperi, rhizome of chuanxiong, peach kernel, the RADIX CURCUMAE stirred evenly, opens stirring, mixing speed 30r/min, and stirring adds after sixty minutes
Enter borneol, continuation is down to after mixing evenly to be stored at room temperature.
(3) load of medical fluid: precoat is impregnated in active medical fluid, is supported on medicine liquid ingredient on fabric, and medical fluid
Quality accounts for the 10% of gross mass.
(4) production of ion stack layer: the composite charged film of polytetrafluoroethylene (PTFE) is charged using dielectric breakdown device, passes through one
Fixed charging voltage charging 100s.
(5) precoat, gluing oxidant layer, ion stack layer and peeling layer are successively closely connected in order, and after being packaged
Finished product can be formed.
Experimental example 5: user is on probation
Cyclomastopathy is women common disease, frequently-occurring disease, is a kind of chronic benign venereal disease.We are applying the cream in the present invention
Health patch treatment the proliferation of mammary gland 28, and combine vitamin B1 with tamoxifen piece and treat 22 controls, it is as a result as follows:
1. data and method
1.1 general information
Whole examples are Breast Clinic Patients of Mammary Gland Hyperplasia, are randomly divided into 2 groups.Treatment group 28, it is the age 18-50 years old, average
(35.0 ± 3) year;The course of disease 0.5 ~ 6 year, average (2.0 ± 0.3) year.Control group 22, the age 20 ~ 60 years old, average (37.0 ± 2)
Year;The course of disease 1 ~ 8 year, average (3.0 ± 0.6) year.2 groups of general information comparing differences are not statistically significant (P > 0.05), and having can
Compare property.
1.2 case selection
1.2.1 1. breast pain majority has periodically diagnostic criteria, and breaking-out has with the menstrual cycle --- and menstruation a few days ago adds
It is heavy, mitigate after menstrual onset or disappears;2. physical examination discovery side or bilateral breast body of gland limitation or diffusivity thicken, lump is in
Graininess nodositas or piece --- not of uniform size, matter is tough without hard, and buildup area is demarcated unclear with surrounding breast tissue;3. this disease is sick
Journey is longer, develops slowly, and is apt to occur in middle-aged women;It is that serosity or slurry are hemorrhagic 4. small number of patients can have nipple discharge.If any upper
2 or more persons are stated, this disease can be confirmed as.
1.2.2 it is included in standard and 1. meets diagnostic criteria;2. women, the age 18 ~ 60 years old.
1.2.3 1. exclusion criteria external application or takes other treatment proliferation of mammary gland medicines and operative treatment during diagnosis and treatment
Person;2. suffering from serious cardiovascular and cerebrovascular disease, mental disease and other major diseases patient;3. slurred speech, it is difficult to exchange, compliance
Poor patient.
1.2.4 rejecting concurrent other diseases 1. standard is treated during needs curer;2. increasing other without authorization during treatment
Therapeutic scheme person;3. because therapeutic response seriously can not resistance to receptor during treatment.
1.3 treatment method
1.3.1 control group 1. bland diet;2. tamoxifen piece (ShangHai Fudan Fuhua Pharmaceutical Co., Ltd, national drug standard
H31021545) 10mg takes orally 2 times a day;3. vitamin B piece 10mg, takes orally 3 times a day.
1.3.2 the direct application for the treatment of group product cream health patch of the invention, it is daily to apply 2 patches.
1.3.3 the course for the treatment of and other 2 groups equal 10 days be 1 course for the treatment of, the spicy food of the prohibition of life tinkling of pieces of jade, the menstrual period be discontinued, continuous 1
Moon observation curative effect.
The criterion of therapeutical effect that 1.4 criterions of therapeutical effect are worked out according to All-China Association of Traditional Chinese Medicine's surgery mastosis special topic group.Face
Bed is cured: cream pain or newborn block disappear, and do not recur within 3 months after drug withdrawal;Effective: lump maximum gauge reduces 1/2 or more, and pain disappears
It loses;Effective: lump maximum gauge is reduced less than 1/2 or more, and pain relief or lump maximum gauge reduce 1/2 or more, and pain subtracts
It is light unobvious;Invalid: lump increases the person of being hardened or simple cream pain alleviation without diminution or instead, and lump does not reduce.
1.5 statistical method the data obtaineds use 15.0 statistical software of SPSS, and the comparison of rate uses x2It examines.
2. result
2 groups of curative effects are compared as follows shown in table.
1 two groups of curative effect comparative examples (%) of table
Group | n | Clinical cure | It is effective | Effectively | In vain | Total effective rate (%) |
Treatment group | 28 | 10(35.71) | 15(53.57) | 3(10.71) | 0(0) | 100 |
Control group | 22 | 1(4.5) | 4(18.18) | 2(9.1) | 15(68.18) | 31.82 |
From upper table 1 it is found that two groups effectively statistically significant compared with difference, treatment group's curative effect is better than control group.This is primarily due to
Control group takes drugs merely, palliative, so that the proliferation of mammary gland is easy repeatedly, leads to the effective percentage cured in a short time
It is low.And the product in the present invention incudes treatment technology using drug combination electrostatic ionic, and pain can be effectively relieved, activating microcirculation and removing stasis medicinal,
So that the proliferation of mammary gland is largely inhibited.
It should be pointed out that specific embodiment is the more representational example of the present invention, it is clear that skill of the invention
Art scheme is not limited to the above embodiments, and can also have many variations.Those skilled in the art define public affairs with the present invention
Written description open or according to file is undoubted to be obtained, and this patent scope of the claimed is considered as.
Claims (5)
1. a kind of cream health patch, which is characterized in that by precoat, the gluing oxidant layer being coated on above the precoat, be placed in it is described
On gluing oxidant layer and coverage area be less than the gluing oxidant layer ion stack layer and be placed on the ion stack layer and
Shape size peeling layer identical with the precoat is constituted, and the peeling layer is glossy face tray paper layer.
2. a kind of preparation method of newborn health patch described in claim 1, which comprises the steps of:
(1) production of precoat: precoat by banana fiber, bamboo charcoal fiber and far IR fibre using two-wire weaving weave and
At;
(2) load of medical fluid: the precoat is impregnated in active medical fluid, is supported on medicine liquid ingredient on precoat, and medicine
Liquid quality accounts for the 2% ~ 10% of precoat gross mass;
(3) production of ion stack layer: the ion stack layer is the composite charged film by polytetrafluoroethylene (PTFE) using dielectric breakdown
Device charging is formed by certain 60~120s of charging voltage charging;
(4) precoat, gluing oxidant layer, ion stack layer and peeling layer are successively closely connected in order, and after being packaged
Form finished product.
3. a kind of preparation method of newborn health patch according to claim 2, which is characterized in that in the active medicine liquid ingredient
The parts by weight of each component are as follows: 40 ~ 60 parts of jojoba seed oil, 10 ~ 20 parts of butanediol, 5 ~ 10 parts of olibanum, 1 ~ 10 part of peach kernel, wide strongly fragrant
Golden 2 ~ 8 parts, 7 ~ 13 parts of rhizoma cyperi, 2 ~ 6 parts of rhizome of chuanxiong, 2 ~ 5 parts of skin penetration enhancer, concocting method is as follows:
(1) jojoba seed oil 40 ~ 60%, butanediol 7 ~ 10% are added in ingredients pot, are heated to 80-90 DEG C, speed of agitator 35r/
Min keeps the temperature 30 minutes;
(2) 55 DEG C are cooled to, the olibanum stirred evenly, rhizoma cyperi, rhizome of chuanxiong, peach kernel, RADIX CURCUMAE is added, opens stirring, mixing speed
Skin penetration enhancer is added in 30r/min, stirring after sixty minutes, and continuation is down to after mixing evenly to be stored at room temperature.
4. a kind of preparation method of newborn health patch according to claim 3, which is characterized in that the cutaneous permeable agent is
Azone, oleic acid, N- methyl -2-Pyrrolidone, propylene glycol, any one in borneol.
5. a kind of preparation method of newborn health patch according to claim 2, which is characterized in that banana is fine in the precoat
The weight ratio of dimension, bamboo charcoal fiber and far IR fibre is 1:2:3.
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