CN109199637A - A kind of artificial cornea - Google Patents
A kind of artificial cornea Download PDFInfo
- Publication number
- CN109199637A CN109199637A CN201810224814.1A CN201810224814A CN109199637A CN 109199637 A CN109199637 A CN 109199637A CN 201810224814 A CN201810224814 A CN 201810224814A CN 109199637 A CN109199637 A CN 109199637A
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- CN
- China
- Prior art keywords
- disk
- convex ridge
- back plate
- artificial cornea
- circle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/142—Cornea, e.g. artificial corneae, keratoprostheses or corneal implants for repair of defective corneal tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/145—Corneal inlays, onlays, or lenses for refractive correction
- A61F2/1451—Inlays or onlays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/145—Corneal inlays, onlays, or lenses for refractive correction
- A61F2/1453—Corneal lenses connected to distinct attachment means
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- Health & Medical Sciences (AREA)
- Transplantation (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
The invention discloses a kind of artificial corneas, foreboard, carrier cornea, back plate and titanacycle including having optical frames column, and the forward and backward surface of the optical frames column is polishing design, design around the cylinder of the optical frames column for frosted.The present invention is designed the optical frames column in artificial cornea foreboard, artificial cornea is set to prevent light reflection from generating interference to eyesight, and influence of the ultraviolet light to retina is prevented, the present invention is designed artificial cornea back plate, substantially reduces the incidence of caudacoria covering mirror column.
Description
Technical field
The present invention relates to a kind of artificial corneas.
Background technique
Artificial cornea be replace muddy cornea tissue and alloplastic material made of a kind of special refractive apparatus, pass through hand
Eye is suffered from art implantation, to obtain certain eyesight.Clinically keratoprosthesis implantation is using more for the institute of ophthalmology Lions, Australia
The AlphaCor artificial cornea of research and development, the bone flute profile artificial cornea of Italian Strampelli invention and the artificial angle of boston, U.S.A
Film.In addition there is Fyodorov-Zuev artificial cornea in the former Soviet Union, and there be people from Boston of Soul type artificial cornea and India's improvement in South Korea
Work cornea.This artificial cornea has made innovative improvement on the basis of global existing artificial cornea.
Summary of the invention
The purpose of the present invention is to provide a kind of artificial corneas.
To achieve the above object, the technical scheme adopted by the invention is as follows: a kind of artificial cornea, including have optical frames column
Foreboard and back plate, the forward and backward surface of the optical frames column be polishing design, be around the cylinder of the optical frames column
Frosted design.
As the preferred embodiment of the present invention, the rear surface of the optical frames column is plane.
As the preferred embodiment of the present invention, the optical frames column designs for snap ring-type.
As the preferred embodiment of the present invention, the material of the foreboard is the medical PMMA with antiultraviolet.
As the preferred embodiment of the present invention, the back plate is the disk with mesoporous, and the disk is equipped with 10
Lateral opening, the disk is equipped with round convex ridge, and the circle convex ridge is the cylindrical body of inner hollow, the center of the circle convex ridge
Line is overlapped with the center line of the disk.
As the preferred embodiment of the present invention, the circle convex ridge with a thickness of 0.2mm, the height of the circle convex ridge
For 0.4mm.
As the preferred embodiment of the present invention, the disk is medical titanium disk, and the circle convex ridge is metal convex ridge.
As the preferred embodiment of the present invention, the internal diameter of round convex ridge is 4.7mm, and the median pore diameter is 3.2mm,
The lateral opening diameter is 1mm, and the diameter of the disk is 8.5mm.
As the preferred embodiment of the present invention, 10 lateral opening centers of circle are located on same circumference, in the circumference
Heart line is overlapped with the center line of the disk, and it is described 10 it is lateral opening in it is adjacent it is lateral opening between circle center distance be equal.
As the preferred embodiment of the present invention, 10 lateral opening centers of circle connect the diameter of a circle to be formed and are
6.6mm。
As the preferred embodiment of the present invention, the diameter of the disk is 8.5mm.
As the preferred embodiment of the present invention, the disk is arc disk, and the side of the disk is arc.
As the preferred embodiment of the present invention, the front surface radian of the arc disk is 6.3, the arc disk
Rear surface radian is 8.0.
As the preferred embodiment of the present invention, the back plate is the disk with mesoporous, and the disk is equipped with 3 sides
Hole forms trifolium-shaped disk, and the disk is equipped with round convex ridge, and the circle convex ridge is the cylindrical body of inner hollow, described
Round convex ridge be located at the mesoporous and it is described it is lateral opening between, it is described circle convex ridge center line and the disk center line weight
It closes.
As the preferred embodiment of the present invention, the circle convex ridge with a thickness of 0.2mm, the height of the circle convex ridge
For 0.4mm.
As the preferred embodiment of the present invention, the disk is medical titanium disk, and the circle convex ridge is metal convex ridge.
As the preferred embodiment of the present invention, the internal diameter of the circle convex ridge is 4.7mm, and the median pore diameter is
3.2mm, the diameter of the disk are 8.5mm.
As the preferred embodiment of the present invention, the distance between described lateral opening and described disk outer surface is 0.7mm.
As the preferred embodiment of the present invention, it is adjacent it is the distance between lateral opening be 0.8mm.
As the preferred embodiment of the present invention, the disk is arc disk, and the side of the disk is arc.
As the preferred embodiment of the present invention, the front surface radian of the arc disk is 6.3, the arc disk
Rear surface radian is 8.0.
Artificial cornea of the present invention includes the foreboard with optical frames column, and diopter is determined by the front surface radian of foreboard
Fixed, the rear surface of foreboard mirror column is plane, and the front and rear surfaces of mirror column use frosted using polishing design around the cylinder of mirror column
Design, prevents the reflections affect eyesight of light.Mirror column is designed using snap ring-type.The material of foreboard is with the medical of antiultraviolet
PMMA, to prevent influence of the ultraviolet light to retina.The material of back plate is medical titanium, and there are two types of design, one kind is that 10 holes are designed,
But it is equipped with one week 0.2mm thickness in the middle circumference of back plate, the purpose of the convex ridge of 0.4mm high, this improvement is: previous clinic is ground
Study carefully the formation that the display postoperative most common complication of Boston artificial cornea is mirror column caudacoria, some document reports its incidences is very
Up to 50% or more, this generally requires laser therapy.And thicker caudacoria laser energy will cause greatly very much to mirror column rear surface
Destruction, to influence optical imagery.At this moment intraocular surgery intervention is just needed, will increase intraocular hemorrhage at this time, retina is de-
From in addition entophthamia risk, therefore the best preventive measure be prevent caudacoria cover mirror column.It is previous researches show that caudacoria
Generation be between carrier cornea and plant bed keratocyte migrate backward growth cause, can increase back plate diameter prevention.But
The diameter for increasing back plate increases operation simultaneously and is implanted into intraocular difficulty, while the back plate for crossing major diameter is possible to generate room angle
It influences, is improved so as to cause the incidence of postoperative glaucoma.Artificial cornea back plate of the present invention is possible to substantially reduce caudacoria covering
The incidence of mirror column.In addition a selective back plate is designed as trifolium-shaped titanium back plate, is increasing carrier cornea and aqueous humor
(improve corneal nutrition and aquation) while contact, also circumference designs a circumferential ridge to prevent caudacoria from covering mirror in titanium back plate
Column.The mirror column quality of optical imaging for improveing artificial cornea simultaneously will be detected using point spread function.
Compared with prior art, the beneficial effects of the present invention are: the present invention is to the optical frames column in artificial cornea foreboard
It is designed, enables artificial cornea to prevent light reflection from generating interference to eyesight, and prevent ultraviolet light to the shadow of retina
It rings, the present invention is designed artificial cornea back plate, substantially reduces the incidence of caudacoria covering mirror column.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of artificial cornea described in the embodiment of the present invention 1；
Fig. 2 is the structural schematic diagram of the foreboard of artificial cornea described in the embodiment of the present invention 1；
Fig. 3 is the structural schematic diagram of the back plate of artificial cornea described in the embodiment of the present invention 1；
Fig. 4 is the structural schematic diagram of artificial cornea described in the embodiment of the present invention 2；
Fig. 5 is the structural schematic diagram of the back plate of artificial cornea described in the embodiment of the present invention 2.
Specific embodiment
Embodiment 1
A kind of embodiment of artificial cornea of the present invention, as shown in Figure 1, including foreboard 1, carrier cornea with optical frames column
2, back plate 3 and titanacycle 4.
The foreboard be have the foreboard 1 with optical frames column 11, as shown in Fig. 2, the optical frames column 11 be located at it is described before
The center of the rear surface 12 of plate 1, the front surface 13 of the foreboard 1 are the design of convex radian, diopter by foreboard 1 front surface
13 radians determine that the rear surface 5 of optical frames column 11 is plane, and the forward and backward surface of optical frames column 11 is designed using polishing, and optics
The cylinder outer wall of mirror column 11 is designed using frosted, prevents the reflections affect eyesight of light.Optical frames column is designed using snap ring-type.
The size of artificial cornea foreboard is designed, it is preferable that the foreboard is arc disk, the diameter of the foreboard
D1 is 5mm.Preferably, the optical area diameter d2 of the optical frames column is 3.5mm.
The material of foreboard is the medical PMMA with antiultraviolet, to prevent influence of the ultraviolet light to retina.
The back plate, as shown in figure 3, the back plate 3 is the disk with mesoporous 21, the disk is lateral opening equipped with 10
22, setting described lateral opening 22 is to allow aqueous humor through nourishing carrier cornea；The disk is equipped with round convex ridge 23, the circle
Shape convex ridge 23 is the cylindrical body of inner hollow, and it is the formation in order to prevent mirror column caudacoria, the circle that the round convex ridge 23, which is arranged,
The center line of shape convex ridge 23 is overlapped with the center line of the disk.
The present invention is designed the various sizes of back plate:
Preferably, the thickness (distance of the inner wall of round convex ridge 23 to outer wall) of the round convex ridge 23 is 0.2mm, institute
The height for stating round convex ridge 23 is 0.4mm.
Preferably, the round convex ridge 23 is metal convex ridge.
Preferably, the internal diameter of round convex ridge 23 is 4.7mm.
Preferably, the diameter d3 of the mesoporous 21 is 3.2mm, and lateral opening 22 diameter is 1mm.
Preferably, 10 lateral opening 22 centers of circle are located on same circumference, the center line of the circumference and the disk
Center line be overlapped, and in described 10 lateral opening 22 it is adjacent it is lateral opening between circle center distance be equal.
Preferably, it is 6.6mm that 10 lateral opening 22 centers of circle, which connect the diameter of a circle d4 to be formed,.
Preferably, the diameter d5 of the disk is 8.5mm.
Preferably, the side of the disk is arc, and being set as arc here is to make artificial angle to meet corneal curvature
Film is preferably merged with plant bed.
Preferably, 24 radian of rear surface of the arc disk is 8.0, and the front surface radian of the arc disk is 6.3.
The back plate can substantially reduce the incidence of caudacoria covering mirror column.
Equipped with the mesoporous to match with optical frames column 11, (diameter of the mesoporous is slightly larger than optics in 2 center of carrier cornea
The diameter of mirror column 11), it is fitted snugly on optical frames column 11 conducive to carrier cornea 2, the rear surface 12 and the load of the foreboard
The front surface of body cornea 2 is bonded, and 21 diameter of mesoporous of the back plate 3 and the diameter of the optical frames column 11 match the (mesoporous 2
Diameter be slightly larger than optical frames column 11 diameter), be fitted snugly on optical frames column 11 conducive to back plate 3, the optical frames column 11
It is equipped with external screw thread, the inner wall of the mesoporous of the back plate 3 is equipped with internal screw thread compatible with the external screw thread of the optical frames column 11,
The titanacycle 4 can be screwed along the external screw thread of optical frames column 11.Carrier cornea 2 is inserted in optical frames using when artificial cornea of the present invention
Then column 11 is successively inserted in back plate 3 and titanacycle 4, and screwing titanacycle 4 makes artificial cornea at watertight state.
Embodiment 2
A kind of embodiment of artificial cornea of the present invention, as shown in figure 4, including foreboard 1, carrier cornea with optical frames column
2, back plate 5 and titanacycle 4.
Foreboard of the foreboard 1 with embodiment 1.
The back plate 5 designs for trifolium-shaped, as shown in figure 5, the back plate 5 is the disk with mesoporous 31, the circle
Disk is equipped with 3 lateral opening 32 and forms trifolium-shaped disk, and the disk is equipped with round convex ridge 33, and the circle convex ridge 33 is
The cylindrical body of inner hollow, the circle convex ridge 33 is between the mesoporous 31 and described lateral opening 32, the circle convex ridge 33
Center line be overlapped with the center line of the disk.The design (improves angle while increasing carrier cornea 2 and aqueous humor contacts
Film nutrition and aquation), also circumference designs a circumferential ridge 33 to prevent caudacoria from covering mirror column in back plate 5.
Preferably, the thickness (distance of the inner wall of round convex ridge 33 to outer wall) of the round convex ridge 33 is 0.2mm, institute
The height for stating round convex ridge 33 is 0.4mm.
Preferably, the disk is medical titanium disk, and the circle convex ridge 33 is metal convex ridge.
Preferably, the internal diameter of the round convex ridge 33 is 4.7mm.
Preferably, 31 diameter of mesoporous is 3.2mm, and the diameter d6 of the disk is 8.5mm.
Preferably, the distance between described lateral opening 32 and the disk outer surface L1 are 0.7mm.
Preferably, adjacent lateral opening the distance between 32 L2 is 0.8mm.
Preferably, the disk is arc disk, and the side of the disk is arc, and being set as arc here is to accord with
Corneal curvature is closed, merges artificial cornea preferably with plant bed.
Preferably, the front surface radian of the arc disk is 6.3, and the rear surface radian of the arc disk is 8.0.
By above-mentioned design, while which farthest supports cornea carrier, allow aqueous humor and carrier cornea most
The contact of large area allows aqueous humor sufficiently to nourish carrier cornea, reduces the probability of carrier corneal solution.
2 center of carrier cornea is equipped with mesoporous compatible with optical frames column 11, and (diameter of the mesoporous is slightly larger than optics
The diameter of mirror column 11), it is fitted snugly on optical frames column 11 conducive to carrier cornea 2, the rear surface 12 and the load of the foreboard
The front surface of body cornea 2 is bonded, and 31 diameter of mesoporous of the back plate 5 is adapted the (mesoporous 2 with the diameter of the optical frames column 11
Diameter be slightly larger than optical frames column 11 diameter), be fitted snugly on optical frames column 11 conducive to back plate 5, the optical frames column 11
It is equipped with external screw thread, the inner wall of the mesoporous of the back plate 5 is equipped with internal screw thread compatible with the external screw thread of the optical frames column 11,
The titanacycle 4 can be screwed along the external screw thread of optical frames column 11.Carrier cornea 2 is inserted in optics using when artificial cornea of the present invention
Then mirror column 11 is successively inserted in back plate 5 and titanacycle 4, and screwing titanacycle 4 makes artificial cornea at watertight state.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than protects to the present invention
The limitation of range is protected, although the invention is described in detail with reference to the preferred embodiments, those skilled in the art should
Understand, it can be with modification or equivalent replacement of the technical solution of the present invention are made, without departing from the essence of technical solution of the present invention
And range.
Claims (10)
1. a kind of artificial cornea, which is characterized in that foreboard, carrier cornea, back plate and titanacycle including having optical frames column, institute
The forward and backward surface for stating optical frames column is polishing design, is designed around the cylinder of the optical frames column for frosted.
2. artificial cornea according to claim 1, which is characterized in that the back plate is the disk with mesoporous, the circle
Disk is lateral opening equipped with 10, and the disk is equipped with round convex ridge, and the circle convex ridge is the cylindrical body of inner hollow, the circle
The center line of shape convex ridge is overlapped with the center line of the disk.
3. artificial cornea according to claim 2, which is characterized in that it is described circle convex ridge with a thickness of 0.2mm, the circle
The height of shape convex ridge is 0.4mm.
4. artificial cornea back plate according to claim 2, which is characterized in that the internal diameter of round convex ridge be 4.7mm, it is described in
Bore dia is 3.2mm, and the lateral opening diameter is 1mm, and the diameter of the disk is 8.5mm.
5. artificial cornea back plate according to claim 2, which is characterized in that the disk is arc disk, the disk
Side be arc, the front surface radian of the arc disk is 6.3, and the rear surface radian of the arc disk is 8.0.
6. artificial cornea back plate according to claim 1, which is characterized in that the back plate is the disk with mesoporous, institute
Disk is stated equipped with 3 lateral opening formation trifolium-shaped disks, the disk is equipped with round convex ridge, and the circle convex ridge is inside
Hollow cylindrical body, the circle convex ridge be located at the mesoporous and it is described it is lateral opening between, the center line of the round convex ridge and institute
The center line for stating disk is overlapped.
7. artificial cornea back plate according to claim 6, which is characterized in that it is described circle convex ridge with a thickness of 0.2mm, institute
The height for stating round convex ridge is 0.4mm.
8. artificial cornea back plate according to claim 6, which is characterized in that the internal diameter of the circle convex ridge is 4.7mm, institute
Stating median pore diameter is 3.2mm, and the diameter of the disk is 8.5mm.
9. artificial cornea back plate according to claim 6, which is characterized in that described lateral opening between the disk outer surface
Distance be 0.7mm.
10. artificial cornea back plate according to claim 6, which is characterized in that it is adjacent it is the distance between lateral opening be 0.8mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810224814.1A CN109199637B (en) | 2018-03-19 | 2018-03-19 | Artificial cornea |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810224814.1A CN109199637B (en) | 2018-03-19 | 2018-03-19 | Artificial cornea |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109199637A true CN109199637A (en) | 2019-01-15 |
| CN109199637B CN109199637B (en) | 2021-05-04 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810224814.1A Active CN109199637B (en) | 2018-03-19 | 2018-03-19 | Artificial cornea |
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| CN (1) | CN109199637B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110025402A (en) * | 2019-05-21 | 2019-07-19 | 王丽强 | Artificial cornea containing biomaterial |
| CN112168425A (en) * | 2020-04-13 | 2021-01-05 | 广东佳悦美视生物科技有限公司 | Method for preparing artificial cornea posterior plate |
| CN112372005A (en) * | 2020-04-13 | 2021-02-19 | 广东佳悦美视生物科技有限公司 | Preparation method of collar button type artificial cornea |
| CN112872714A (en) * | 2020-04-13 | 2021-06-01 | 广东佳悦美视生物科技有限公司 | Preparation method of artificial cornea collar |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110025402A (en) * | 2019-05-21 | 2019-07-19 | 王丽强 | Artificial cornea containing biomaterial |
| CN110025402B (en) * | 2019-05-21 | 2021-09-24 | 王丽强 | Artificial cornea containing biological material |
| CN112168425A (en) * | 2020-04-13 | 2021-01-05 | 广东佳悦美视生物科技有限公司 | Method for preparing artificial cornea posterior plate |
| CN112372005A (en) * | 2020-04-13 | 2021-02-19 | 广东佳悦美视生物科技有限公司 | Preparation method of collar button type artificial cornea |
| CN112872714A (en) * | 2020-04-13 | 2021-06-01 | 广东佳悦美视生物科技有限公司 | Preparation method of artificial cornea collar |
| CN112872714B (en) * | 2020-04-13 | 2022-08-12 | 广东佳悦美视生物科技有限公司 | Preparation method of artificial cornea collar |
| CN112372005B (en) * | 2020-04-13 | 2023-12-19 | 广东佳悦美视生物科技有限公司 | Preparation method of collar buckle type artificial cornea |
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|---|---|
| CN109199637B (en) | 2021-05-04 |
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