CN101283933A - Artificial crystalline lens of blocking eaves type limitation after cataract - Google Patents
Artificial crystalline lens of blocking eaves type limitation after cataract Download PDFInfo
- Publication number
- CN101283933A CN101283933A CNA2008100642525A CN200810064252A CN101283933A CN 101283933 A CN101283933 A CN 101283933A CN A2008100642525 A CNA2008100642525 A CN A2008100642525A CN 200810064252 A CN200810064252 A CN 200810064252A CN 101283933 A CN101283933 A CN 101283933A
- Authority
- CN
- China
- Prior art keywords
- eaves
- intraocular lens
- cataract
- blocking
- lens
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Landscapes
- Prostheses (AREA)
Abstract
A barrier-type artificial intraocular lens for preventing after cataract relates to an artificial intraocular lens, which aims to solve the problem that after cataract occurs due to the hyperplasia and transition of cortex cells close to ambitus along the rear surface of the artificial intraocular lens since very large lens capsule and subcapsular cortex is kept in prior art after extracting cataract and implanting the artificial intraocular lens. In the invention, two lens support bands (2) are fixed on both sides of the ambitus (3) of the artificial intraocular lens (1), and one side of a circular cylinder (4) is connected with the rear surface of the artificial intraocular lens (1) and the other side is connected with barriers (6). The barriers of the invention can effectively prevent hyperplasia and transition of lens capsule cells from front to rear. A drug controlled-release carrier slowly releases drugs for suppressing hyperplasia of epithelial cells in the lens capsule, thus suppressing or preventing hyperplasia of epithelial cells in the lens capsule. The invention can prevent the occurrence of after cataract from two sides.
Description
Technical field
The present invention relates to a kind of intraocular lens.
Background technology
Cataract is commonly encountered diseases, the frequently-occurring disease of ophthalmology, is main blinding oculopathy (is first of the blinding oculopathy in some country).At present, the blind unique method of treatment cataract is the crystalline lens of surgical removal muddiness.In order to compensate the height ametropia (usually being high hypermetropia) that " aphakic eye " that form behind the cataract extraction causes, need to implant an intraocular lens.Generally when extracing cataract, implant in an operation process, operator is at twice also arranged.No matter once operation or gradation operation after the implantable artificial crystalline lens, exists a very big problem still unresolved so far good, that is exactly the after cataract of intraocular lens's rear surface formation.Though its root is original self crystalline lens surgical removal, but owing to kept considerable crystalline peplos and cyst membrane hypopallium cell, near the ambitus cyst membrane cortex cell along intraocular lens's rear surface backward hypertrophy, divide a word with a hyphen at the end of a line, form the rear surface of dregs attached to the intraocular lens, block optical axis (mainly being the optical axis) and form film sample muddiness, cause visual disorder again, be called as after cataract.This problem is made us puzzlement for a long time always, and especially there is treatment contradiction especially in the cataract infant to the little age, on the one hand, need perform the operation as early as possible, if postpone treatment, operation is late will to influence the visual performance growth, and then forms amblyopia, leaves a legacy of trouble to throughout one's life.On the other hand, operating time early more increased the probability that forms after cataract, still can cause the secondary blinding.It is very difficult that the intraocular lens is changed in operation again, uses additive method and also have any problem.Afterwards and behind the implantable artificial crystalline lens also there is this problem in cataract patient operation to other ages.After forming after cataract, the method that useful laser punches after cataract, but, very easily damage the intraocular lens during operation because after cataract tightly is attached to intraocular lens's rear surface.These drawbacks make after cataract become the cataractous a great problem of operative treatment.
Summary of the invention
The objective of the invention is to have now after extracing cataract implantable artificial crystalline lens for solving, owing to kept sizable crystalline peplos and cyst membrane hypopallium, near the ambitus cortex cell along intraocular lens's rear surface backward hypertrophy, divide a word with a hyphen at the end of a line, form the rear surface of dregs attached to the intraocular lens, block optical axis and form film sample muddiness, be the problem of after cataract, a kind of intraocular lens of blocking eaves type limitation after cataract is provided.The present invention comprises intraocular lens 1 and two crystalline lens support buttons loop 2, two crystalline lens support buttons loop 2 are fixed on the both sides of intraocular lens 1 ambitus 3, the present invention also comprises circular cylinder 4 and retaining eaves 6, the center of retaining eaves 6 has through hole 7, one side of circular cylinder 4 is connected with intraocular lens 1 rear surface, and the opposite side of circular cylinder 4 is connected with retaining eaves 6.Described retaining eaves 6 is for interior retaining eaves 6-1 or keep off eaves 6-2 outward.The present invention connect in the intraocular lens back one with the same material of intraocular lens, transparent outer retaining eaves or interior retaining eaves equally, between intraocular lens and retaining eaves, connect one with the same material of intraocular lens, same transparent circular cylinder, keep off eaves outward as on intraocular lens's rear surface, connecting a retaining eaves that pushes up " cowboy's hat " or " carnival hat ".Slit between retaining eaves the place ahead and intraocular lens back is known as " retaining preceding slit of eaves or gap ", nucleus lentis that will be muddy when the implantable artificial crystalline lens and other muddy cortex extraction or sucking-off, the appropriate back cyst membrane that tears the part central area, keep central area (optical axis district) back cyst membrane in addition, the rear surface that makes the intraocular lens and retaining eaves are clamped in cyst membrane both sides behind the periphery that retains, that is to say, place among retaining preceding slit of eaves or the gap tearing behind the surrounding zone that retains behind the cyst membrane behind the central area position of cyst membrane.Even its objective is to make the hypertrophy or the expansion of dividing a word with a hyphen at the end of a line backward of operation back crystalline peplos hypopallium cell, also can only terminate in outside the circular cylinder of keeping off between eaves and the intraocular lens rear surface, and can't arrive intraocular lens's optical axis district along the front surface of retaining eaves.Retaining eaves of the present invention has effectively stopped in the past hypertrophy and dividing a word with a hyphen at the end of a line backward of phacocyst theca cell.Slow down or prevented the generation of after cataract.
Description of drawings
Fig. 1 is an overall structure sketch map of the present invention,
Fig. 2 is the A-A cutaway view of Fig. 1,
Fig. 3 is the structural representation of the specific embodiment four,
Fig. 4 is the structural representation of the specific embodiment five,
Fig. 5 is the structural representation of the specific embodiment two,
Fig. 6 is the structural representation of the specific embodiment six,
Fig. 7 is the structural representation of the specific embodiment seven.
The specific embodiment
The specific embodiment one: as Fig. 1～shown in Figure 7, present embodiment is made up of intraocular lens 1, two crystalline lens support buttons loop 2, circular cylinder 4 and retaining eaves 6, two crystalline lens support buttons loop 2 are fixed on the both sides of intraocular lens 1 ambitus 3, the center of retaining eaves 6 has through hole 7, one side of circular cylinder 4 is connected with intraocular lens 1 rear surface, and the opposite side of circular cylinder 4 is connected with retaining eaves 6.Described retaining eaves 6 is for interior retaining eaves 6-1 or keep off eaves 6-2 outward.
The specific embodiment two: as Fig. 2, shown in Figure 5, the difference of the present embodiment and the specific embodiment one is, it also increases slow releasing carrier of medication 5, in slow releasing carrier of medication 5 is fixed on the trailing flank of retaining eaves 6-1 or keep off on the leading flank of eaves 6-2 outward or on the outer surface of circular cylinder 4 or on the intraocular lens's 1 in circular cylinder 4 outsides the rear surface.Other composition is identical with the specific embodiment one with annexation.The slow releasing carrier of medication 5 that increases can increase the content of slow releasing pharmaceutical on the one hand, can more effectively prevent phacocyst theca cell hypertrophy and dividing a word with a hyphen at the end of a line backward in the past on the other hand the release time of prolong drug, has certain effect to preventing after cataract.The material of described slow releasing carrier of medication 5 is the porous sustained-release material, as wherein any of collagen cover, liposome, polyvinyl alcohol, Ethyl vinylacetate, poly--3 butyric esters, butyric ester-hydroxyl pentanoate copolymer (PHBV), PHBV and gelatin double-decker material, ethyl cellulose, acrylic resin or Helicid hydrophilic gel.Slow releasing pharmaceutical on the slow releasing carrier of medication 5 is a rapamycin, glucocorticoid, the retinoic acid sodium grain of rice, elemene, ametycin, interleukin-6 antisense oligonucleotide lipid, 5-fluorouracil, heparin, all-trans-retinoic acid, amycin, ricin, saporin, CAPE, interferon, total alkaloid of harmaline, homoharringtonine, methotrexate, daunorubicin, ciclosporin A, hanfangchine, rubescensine A, saponin, suramin, genitein, mannose ester, diclofenac, wherein any of dexamethasone or retinoic acid.Its manufacture method is that the slow releasing carrier of medication 5 of described material was put into described slow releasing pharmaceutical 30 minutes to 10 hours, packs then to get final product under aseptic condition.Perhaps before being implanted, the intraocular lens in sterile liquid medicine, fully soaks.
The specific embodiment three: as Fig. 2, shown in Figure 5, present embodiment retaining eaves 6 is a butterfly.Other composition is identical with the specific embodiment one with annexation.
The specific embodiment four: as shown in Figure 3, present embodiment retaining eaves 6 is a bowl-type.Other composition is identical with the specific embodiment one with annexation.
The specific embodiment five: as shown in Figure 4, the section of present embodiment retaining eaves 6 is a stairstepping.Other composition is identical with the specific embodiment one with annexation.
The specific embodiment six: as shown in Figure 6, the section of present embodiment retaining eaves 6 is a zigzag.Other composition is identical with the specific embodiment one with annexation.
The specific embodiment seven: as shown in Figure 7, the section of present embodiment retaining eaves 6 is a crenel shape.Other composition is identical with the specific embodiment one with annexation.
The structure of the specific embodiment five retaining eaves 6 to the specific embodiment seven be exactly for prolong the cyst membrane cortex cell along intraocular lens's rear surface the length of hypertrophy, the distance of dividing a word with a hyphen at the end of a line backward, also make the slow releasing pharmaceutical of slow releasing carrier of medication 5 further suppress the hypertrophy of cyst membrane cortex cell.
Claims (10)
1, a kind of intraocular lens of blocking eaves type limitation after cataract, it comprises intraocular lens (1) and two crystalline lens support buttons loop (2), two crystalline lens support buttons loop (2) are fixed on the both sides of intraocular lens (1) ambitus (3), it is characterized in that it also comprises circular cylinder (4) and retaining eaves (6), the center of retaining eaves (6) has through hole (7), one side of circular cylinder (4) is connected with intraocular lens's (1) rear surface, and the opposite side of circular cylinder (4) is connected with retaining eaves (6).
2, the intraocular lens of blocking eaves type limitation after cataract according to claim 1 is characterized in that described retaining eaves (6) is interior retaining eaves (6-1) or keeps off eaves (6-2) outward.
3, the intraocular lens of blocking eaves type limitation after cataract according to claim 2, it is characterized in that it also includes slow releasing carrier of medication (5), in slow releasing carrier of medication (5) is fixed on the trailing flank of retaining eaves (6-1) or keep off on the leading flank of eaves (6-2) outward or on the outer surface of circular cylinder (4) or on the intraocular lens's (1) in circular cylinder (4) outside the rear surface.
4, the intraocular lens of blocking eaves type limitation after cataract according to claim 2 is characterized in that keeping off eaves (6) and is butterfly.
5, the intraocular lens of blocking eaves type limitation after cataract according to claim 2 is characterized in that keeping off eaves (6) and is bowl-type.
6, the intraocular lens of blocking eaves type limitation after cataract according to claim 2, the section that it is characterized in that keeping off eaves (6) is a stairstepping.
7, the intraocular lens of blocking eaves type limitation after cataract according to claim 2, the section that it is characterized in that keeping off eaves (6) is a zigzag.
8, the intraocular lens of blocking eaves type limitation after cataract according to claim 2, the section that it is characterized in that keeping off eaves (6) is a crenel shape.
9, the intraocular lens of blocking eaves type limitation after cataract according to claim 3, the material that it is characterized in that described slow releasing carrier of medication (5) is wherein any of collagen cover, liposome, polyvinyl alcohol, Ethyl vinylacetate, poly--3 butyric esters, butyric ester-hydroxyl pentanoate copolymer, ethyl cellulose, acrylic resin or Helicid hydrophilic gel.
10, the intraocular lens of blocking eaves type limitation after cataract according to claim 9 is characterized in that the slow releasing pharmaceutical on the described slow releasing carrier of medication (5) is a rapamycin, glucocorticoid, the retinoic acid sodium grain of rice, elemene, ametycin, interleukin-6 antisense oligonucleotide lipid, 5-fluorouracil, heparin, all-trans-retinoic acid, amycin, ricin, saporin, CAPE, interferon, total alkaloid of harmaline, homoharringtonine, methotrexate, daunorubicin, ciclosporin A, hanfangchine, rubescensine A, saponin, suramin, genitein, mannose ester, diclofenac, wherein any of dexamethasone or retinoic acid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100642525A CN101283933B (en) | 2008-04-07 | 2008-04-07 | Artificial crystalline lens of blocking eaves type limitation after cataract |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100642525A CN101283933B (en) | 2008-04-07 | 2008-04-07 | Artificial crystalline lens of blocking eaves type limitation after cataract |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101283933A true CN101283933A (en) | 2008-10-15 |
| CN101283933B CN101283933B (en) | 2010-09-15 |
Family
ID=40056498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008100642525A Expired - Fee Related CN101283933B (en) | 2008-04-07 | 2008-04-07 | Artificial crystalline lens of blocking eaves type limitation after cataract |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101283933B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104352289A (en) * | 2014-10-27 | 2015-02-18 | 浙江大学 | Intraocular lens loaded with drug slow-releasing thin layers on loop surfaces |
| CN109009566A (en) * | 2017-08-29 | 2018-12-18 | 东莞东阳光科研发有限公司 | A kind of artificial lens |
| CN109199637A (en) * | 2018-03-19 | 2019-01-15 | 广东博视敦生物科技有限公司 | A kind of artificial cornea |
| WO2023274186A1 (en) * | 2021-06-28 | 2023-01-05 | 国科温州研究院(温州生物材料与工程研究所) | Metasurface-based intraocular lens |
-
2008
- 2008-04-07 CN CN2008100642525A patent/CN101283933B/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104352289A (en) * | 2014-10-27 | 2015-02-18 | 浙江大学 | Intraocular lens loaded with drug slow-releasing thin layers on loop surfaces |
| CN109009566A (en) * | 2017-08-29 | 2018-12-18 | 东莞东阳光科研发有限公司 | A kind of artificial lens |
| CN109009566B (en) * | 2017-08-29 | 2024-04-26 | 东莞东阳光医疗智能器件研发有限公司 | Artificial crystal |
| CN109199637A (en) * | 2018-03-19 | 2019-01-15 | 广东博视敦生物科技有限公司 | A kind of artificial cornea |
| CN109199637B (en) * | 2018-03-19 | 2021-05-04 | 广东佳悦美视生物科技有限公司 | Artificial cornea |
| WO2023274186A1 (en) * | 2021-06-28 | 2023-01-05 | 国科温州研究院(温州生物材料与工程研究所) | Metasurface-based intraocular lens |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101283933B (en) | 2010-09-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Topping et al. | Experimental double-perforating injury of the posterior segment in rabbit eyes: the natural history of intraocular proliferation | |
| Kruger et al. | Two year results: sharp versus rounded optic edges on silicone lenses | |
| Anderson et al. | Morphological recovery in the reattached retina. | |
| Miyake et al. | Liquefied aftercataract: a complication of continuous curvilinear capsulorhexis and intraocular lens implantation in the lens capsule | |
| JP3908592B2 (en) | Sustained release drug delivery device | |
| Ursell et al. | Relationship between intraocular lens biomaterials and posterior capsule opacification | |
| CN101283933B (en) | Artificial crystalline lens of blocking eaves type limitation after cataract | |
| US9999595B2 (en) | Eye device | |
| Blight et al. | Structural changes in the outer retinal layers following blunt mechanical non-perforating trauma to the globe: an experimental study. | |
| Irvine et al. | Retained lens fragments after phacoemulsification manifesting as marked intraocular inflammation with hypopyon | |
| Straatsma et al. | Lens capsule and epithelium in age-related cataract | |
| Orts-Llorca et al. | Experimental production of retinal septa in the chick embryo. Differentiation of pigment epithelium into neural retina | |
| Johnson | The effect of cytochalasin D on outflow facility and the trabecular meshwork of the human eye in perfusion organ culture. | |
| Zambarakji et al. | Capsulorhexis phymosis following uncomplicated phacoemulsification surgery | |
| EP1761253B1 (en) | Hyaluronic acid in the enhancement of lens regeneration | |
| Raghuvanshi et al. | Canine cataracts and its management: An overview | |
| CN201200497Y (en) | Blocked eave type intraocular lens for limiting after cataract | |
| US20060083732A1 (en) | Hyaluronic acid in the enhancement of lens regeneration | |
| CN200973766Y (en) | Artificial lentis for preventing disease after cataract operation | |
| Karling | The cytology of the Chytridiales with special reference to Cladochytrium replicatum | |
| Okada et al. | Newton rings on the surface of implanted intraocular lenses | |
| EP2010100B1 (en) | Materials comprising polysiloxane polymers for enhancement of lens regeneration | |
| Jordan et al. | Postmortem changes in surface preparations of the cochlea | |
| EP2066264B1 (en) | Enhancement of lens regeneration using materials comprising polymers | |
| Hanemoto et al. | Intrascleral fixation of intraocular lens haptics: histological advantages in a comparison with scleral suture fixation in rabbits |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| DD01 | Delivery of document by public notice |
Addressee: Cui Hao Document name: Notification to Pay the Fees |
|
| DD01 | Delivery of document by public notice |
Addressee: Harbin Xingyan Technology Development Co., Ltd. Document name: Notification of Termination of Patent Right |
|
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100915 Termination date: 20120407 |