CN1091898A - Recompounded agricultural chemical with neires toxin - Google Patents

Abstract

A kind of Recompounded agricultural chemical with neires toxin is by sandworm toxin insecticide, and carbamate pesticide and surfactant, organic solvent, thinner is composite forms.This Recompounded pesticide has that cost is low, good disinsection effect, toxicity is low, pest resistance to insecticide is little, is a kind of insecticide of safe, efficient, low-residual, can be widely used in the insect pest of fruit trees such as control cotton, vegetables, citrus.

Description

Recompounded agricultural chemical with neires toxin

The invention belongs to agricultural insecticide, be specifically related to Recompounded agricultural chemical with neires toxin.

Sandworm toxin insecticide is the insecticide of a class bio-imitability, has people and animals safelyr, is easy to degraded, and the lasting period is longer, and insecticidal mechanism is special, insect advantage such as be difficult for developing immunity to drugs, but also the existence effect is slower, shortcomings such as quick-acting difference.With the dimehypo is example, and dimehypo (2-dimethylamino-1, the two thiosulfonic acid sodium propyl group of 3-) is the sandworm toxin insecticide of China's the seventies oneself exploitation, because of action spectrum wider, cost is lower, and has obtained extensive usefulness, becomes the large-tonnage insecticide variety of China's pesticide producing.But also there are many problems in dimehypo: 1, the long-term use made some insects produce pesticide resistance; 2, dimehypo water solution moistening and exhibition on plant and pest body is puted forth effort very poorly, and it is serious easily to be run off by rain drop erosion, causes dosage big, has influenced the drug effect performance; 3, dimehypo is to citrus fruit, and vegetable seedling and cotton have poisoning, has limited the scope of application of dimehypo.For above-mentioned reasons, dimehypo is replaced by other insecticide variety just gradually.

The most of quick-acting of carbamate insecticide are good, but lasting effect is poor, and natural enemy is killed and wounded greatly, to person poultry toxicity's height, easily cause the generation of person poultry poisoning's accident in the use, and insect easily develops immunity to drugs.

Through patent retrieval, still there is not the composite patent of sandworm toxin insecticide and carbamate insecticide.This area patent has only one, and the manufacture method of dual-utility wei pesticide (89103049.2) is with dimehypo and cupric sulfate compounded insecticidal and fungicidal agents.The economic benefits and social benefits prestige has increased fungicidal action, but does not overcome the shortcoming of dimehypo itself, and insecticidal effect does not improve, and insecticidal spectrum does not enlarge, and drug injury problem does not still solve, and the scope of application is still limited to.

The objective of the invention is in order to find a class efficient, economy can overcome pest resistance to insecticide, the composite pesticide that the scope of application is wide.Utilize the advantage of two class agricultural chemicals preferably, overcome pest resistance to insecticide, prolong the service life of two class pesticide species, improve the utilization of pesticides effect, reduce the toxicity of carbamate insecticide, enlarge its scope of application, avoid some insecticides such as dimehypo vegetables to people and animals, the poisoning of citrus and cotton improves its wettability and plate-out ability on plant and polypide.The insecticide of safety, efficient, low-residual is provided for the production of grain, vegetables, cotton and tealeaves.

Recompounded agricultural chemical with neires toxin of the present invention is by sandworm toxin insecticide, carbamate insecticide, and surfactant, solvent and thinner are composite to form, and its compositing range is:

Sandworm toxin insecticide 5-60%(weight)

Carbamate insecticide 2-30%(weight)

Surfactant 1-15%(weight)

Organic solvent 2-30%(weight)

The thinner surplus

Its best compositing range is:

Sandworm toxin insecticide 10-20%

Carbamate insecticide 5-10%

Surfactant 2-8%

Organic solvent 5-10%

The thinner surplus

Wherein, sandworm toxin insecticide can be:

Thiocyclam THIOCYCLAM N, N-dimethyl-1,2,3-trithio

Heterocycle hexane-5-amine

Dimehypo 2-dimethylamino-1, the two thiosulfonic acid sodium of 3-

Base propane

Desinsection list 2-dimethylamino-1-thiosulfonic acid sodium base-3

-thiosulfonic acid base propane

Polythiane 7-dimethylamino-1,2,3,4,5-five sulphur rings

Octane 5-dimethylamino-1,2,3-trithiocyclohexane 4-dimethylamino-1,2-two sulphur pentamethylene

Carbamate insecticide can be:

Carbaryl CARBARYL 1-naphthalene-N-methyl carbamate

Bassa BPMC o-sec-butyl phenyl methyl carbamate

The leaf N-methyl carbamic acid-O-(2 that disperses, the 3-diformazan

The base phenyl) ester

Benfuracard micro (peace gram force) BENFURACARB N-[2,3-two

Hydrogen-2,2-dimethyl benzofuran-7-base oxygen

Carbonyl (methyl) ammonia sulfenyl]-the N-isopropyl

-Beta-alanine ethyl ester

Carbosulfan 2,3-dihydro-2, the 2-dimethyl benzofuran-

7-base-N-(dibutyl amine sulfenyl)-the N-methyl

Carbamate

Mobucin ISOPROCARB o-isopropyl phenyl methyl carbamate

Carbofuran CARBOFURAN 2,3-dihydro-2,2-dimethyl-7-

Benzofuranyl-methyl carbamate

Aphox PIRIMICARB 5,6-dimethyl-2-dimethylamino-4-

Pyrimidine radicals-dimethylcarbamate

Methomyl METHOMYL 1-(methyl mercapto) ethylidene aminomethyl amino

Formic acid esters

UC-51762 N, N '-[two (azomethine base) the carbonyl oxygen bases of sulphur]

The two methyl esters of-diimine thioacetic acid

Tolyl between meta-tolyl-N-methylcarbamate (MTMC) MTMC-N-methyl carbamate

Aldicarb ALDICARB O-(methylamino formoxyl)-the 2-methyl

-2 methyl propanal oxime

Dimethyl phenyl carbamate N-methyl carbamic acid Mixed XYLENE ester

Solvent can be: methyl alcohol, ethanol, acetone, toluene, dimethylbenzene, dimethyl formamide, dimethyl alum etc.

Surfactant can be: anionic, and the mixture of nonionic and anionic and nonionic, or lignosulfite, tea are withered, saponin etc.

Thinner can be: water, organic solvent, or solid carrier such as kaolin, clay, potter's clay, thinner.

When carrying out formula combination, under the prerequisite of synergy certainly, can be according to different physico chemical property decision formula combination.It is stable to have only its aqueous solution to be only as dimehypo, and the aqueous solution of Methomyl also is stable, and both can blend together aqua, with methyl alcohol as cosolvent, with water as thinner; And the solution of desinsection list is unstable, can only be made into solid pharmaceutical preparation.Corresponding thinner is solid carriers such as kaolin, and surfactant is that tea is withered, saponin etc.Listed carbamate insecticide all can be mixed with it; Polythiane is slightly soluble in water, is soluble in benzene and toluene etc., is suitable for being made into missible oil.In the listed carbamate insecticide, except the carbofuran and Aldicarb that are unsuitable for spraying, can be mixed with it.

Advantage of the present invention:

1, use cost is low, the economic benefit height.The desinsection cost is lower by nearly 2/3rds than carbamate insecticides.

2, can overcome pest resistance to insecticide.

3, safety, efficient, low-residual, effectively no poisoning in the extension rate is particularly suitable for the controls of insect of economic crops such as fruit tree, vegetables, tobacco leaf, tea tree, has enlarged the scope of application of sandworm toxin insecticide.

4, the raw materials for production of this agricultural insect pests control agent are easy to get.

5, dimehypo is the pesticide species of the own Development and Production of China, and tens of family factory is arranged, and annual production is in ten thousand tons, and enforcement of the present invention will be created rich profit to China's pesticide industry.

Recompounded agricultural chemical with neires toxin of the present invention is mixed with water-soluble liquor according to quiet with needs, missible oil, and solid pharmaceutical preparation, concrete preparation method can be:

1, carbamate insecticide (a kind of or several) is dissolved in adds dimehypo and surfactant in the organic solvent more earlier, thin up is to stipulating content, be stirred well to evenly water-soluble liquor.

2, earlier former medicine is dissolved in the solvent, adds surfactant again, other composition such as thinner stirs and makes missible oil.

3, with former medicine, filler, pulverizing such as surfactant are sieved, and mixing is made solid pharmaceutical preparation.

Embodiment one

Preparation:

A takes by weighing the former powder of 8KG Methomyl, adds the 8KG industrial methanol, is stirred to dissolving;

B adds 25% dimehypo 66KG;

C adds surfactant farming breast-0204 2KG;

D adds entry 16KG, stirs.

Use: the test of control citrus leaf-miner

1, insect killing effect test

The test of insecticidal effect divides indoor and carry out in the field, and laboratory test is to adopt back the blade of 2-3 order worm alive from the field, and each handles 100.With manual sprayer sprayed in the blade face (generally being the reverse side of blade) that worm is arranged, squirt and get final product.The blade of handling is incubated in culture dish, investigates the dead rate of larva after 48 hours under anatomical lens.

Field trial is that 3 strains trees is selected in every processing in the field, and the choosing of every strain tree has 2-3 to make 20 in the blade of worm, lists before the spray medicine, and 60 blades are hung in a processing altogether.The spraying of employing conventional method, the lethality of 48 hours inspection larvas after the dispenser.

Indoor and field insecticidal test the results are shown in Table 1.

2, tip test is protected in the field

Protect tip test and divide small plot experiment and large-area applications test.The every processing 3 of small plot experiment repeats, every repetition 1 strain tree, and the tip is about 5-10 centimetre during the spray medicine, treats to check when the tip is aging the killed degree of blade after the dispenser, and every strain tree is checked 10 branches altogether.

The large-area applications test prevents and treats 50 mu of areas with 1000 times of liquid.Establish 0.07 hectare simultaneously with 800 times of liquid controls of 24% Methomyl aqua (E.I.Du Pont Company), reach 5 strains contrast tree, to make comparisons.Spray medicine control when the long 5-10CM of the tip treats to examine or check when the tip is aging control efficiency.60 branches of random inspection, 30 branches are looked in contrast, check the killed degree of blade.

That protects tip test the results are shown in Table 2.

The result it seems from table 1, and 800 times of liquid and 1000 times of liquid are 100% lethality at indoor toxic effect to the leaf miner larva.Leaf miner lethality after 3 concentration of field trial are handled is 100.00%, works as with 800 times of liquid phases of 24% Methomyl aqua.

Table 2 shows 600 times of guarantor's tip effects of field plot trial, 800 times, 1000 times of 3 processing are all more than 90%, suitable with guarantor's tip effect of 800 times of liquid 93.9% of 24% Methomyl aqua, the effect of 1000 times of liquid large area control leaf miners also reaches 87.8%, is better than 74.7% of 800 times of liquid of 24% Methomyl aqua.And 24% Methomyl aqua is to produce at present to go up the good medicament that the control leaf miner is generally acknowledged.Embodiment one not only effect makes good use of than Methomyl list, and the toxicity reduction, and is safe in utilization.The control cost less than the Methomyl list use 1/3, have tangible economic benefit.Dimehypo is the insecticide of the different mechanism of action of two classes with Methomyl, and both use with and can delay drug-fast generation effectively.Dimehypo has poisoning to citrus fruit, and embodiment one improves the extension rate of dimehypo, has prevented the generation of poisoning fully.

As shown in Table 2, guarantor's tip effect that embodiment is one 1000 times is apparently higher than 600 times of liquid of 18% dimehypo water solution, except the reason of using synergy with, another very important reasons be exactly that embodiment one contains surfactant, improve the wettability and the plate-out ability of preparation, reduced the loss of soup.

Embodiment two

Preparation:

A. take by weighing desinsection list 60KG;

B. take by weighing Methomyl 30KG;

C. saponin powder 4KG;

D. with the mentioned component crushing screening, mixing soluble powder.

Use:

1, the test of EC against Citrus Aphides

Test divides indoor and carry out in the field.

Laboratory test is to adopt back the blade of more aphid in the field, picks up rapidly soaked for 1 second in treatment fluid after, is put in the culture dish to be incubated, and respectively investigates one time lethality in 24 hours and 48 hours.The results are shown in Table 3.

Field trial is to select the tree of insect density unanimity to be the test tree in the emergence period of citrus aphid, 3 repetitions of every processing, every repetition 1 strain tree.Use the knapsack sprayer even spraying, behind the spray medicine 3 days, every strain tree was checked 100 aphids, the statistics lethality.The results are shown in Table 4.

Laboratory test shows that this medicine has good fragmentation effect to aphid.The further test in field finds out that 230PPM reaches 96.0% to the control efficiency of citrus aphid, demonstrates the fabulous control efficiency of this medicine to aphid, and is suitable with 300PPM24% Methomyl effect, obviously is better than the desinsection list of 500PPM.This prescription has reached reduction toxicity, improves drug effect, reduces the purpose of cost.

2, the test of control citrus psylla

Test method is to take out the phase of sending out at the tender tip of field citrus, and the wood louse nymph sends sprays the medicine processing more for a long time.Every processing 3 repeats, every repetition 2 strains tree.Spray medicine investigation in intact back 24 hours lethality, every strain tree is investigated 20 nymphs.Result of the test sees Table 5.

It seems from table 5,383PPM, 287.5PPM, 230PPM3 the control efficiency of handling the wood louse nymph almost reaches 100%, is the desirable medicament of control wood louse insect

3, the test of control phyllotreta striolata

Test method is that the flea beetle adult is sprayed the medicine processing more for a long time in the vegetable plot.Each concentration of treatment spray one fen ground (about 66.7M ²).Extract 3 1M in each sub-district at random earlier before the spray medicine ²Area investigation insect population radix, 4 hours investigation survivor of a murder attempt number, relatively control efficiency in the original areal extent that extracts behind the spray medicine.See Table 3.

Find out from the result of table 5,383PPM, 287.5PPM, more than 97.2%, effect is fine to the preventive effect of flea beetle for 230PPM3 concentration of treatment.

Embodiment three

Preparation:

A. the former powder 10KG of polythiane;

B. toluene 65KG;

C. dimethyl phenyl carbamate crude oil 13KG;

D. agricultural breast-0204C 10KG

E. earlier A is dissolved among the B, mixes with C.D again, stir missible oil.

Use:

1, the test of control cotton aphid and cotton red spider

At the cotton full-bloom stage with 1000 times of this medicines, 1500 times of conventional sprayings in field, control cotten aphid and two-spotted spider mite the results are shown in Table 7.

As shown in Table 7, under 1000-1500 concentration doubly, still have 80% control efficiency, prove that drug effect is good reaching 90%, the 7 day in 1-3 days after the control efficiency dispenser of cotten aphid and two-spotted spider mite.And find that adult and the larva (aphid snail) of main natural enemy-ladybug of cotten aphid are not had injury, and the cotton of full-bloom stage there is not poisoning, be a kind of better selectivity insecticide that has.And list easily produces poisoning to cotton with polythiane.This product not only has the quick-acting of dimethyl phenyl carbamate, and combines the longer lasting period of polythiane.

The toxic effect of table 1 pair leaf miner larva

The dead borer population lethality of medicament title extension rate investigation borer population corrected mortality

(head) (head) be (%) (%)

One 800 times 103 103 100.0 100.0 of embodiment

1000 times 108 108 100.0 100.0

Contrast 101 17 16.8

One 600 times 62 62 100.0 100.0 of embodiment

800 times 60 60 100.0 100.0

1000 times 61 61 100.0 100.0

800 times 61 61 100.0 100.0 in 24% Methomyl aqua

Contrast 60 11 18.3

Annotate: thick line data up and down are respectively the result of laboratory test and the result of field trial in the table

Table 2 is protected tip result of the test

The killed finger control of the medicament title extension rate investigation number of blade is imitated

0 grade of 1 grade of 2 grades 3 grades 4 progression (%) of sum are (%) really

One 600 times 272 262 10 000 0.9 97.2 of embodiment

800 times 281 257 24 000 2.1 93.6

1000 times 286 265 21 000 1.8 94.5

800 times 253 234 18 100 2.0 93.9 in 24% Methomyl aqua

600 times 258 191 34 19 95 11.5 64.6 of 18% dimehypo water solution

Contrast 207 64 67 42 17 17 32.6

One 1000 times 655 591 51 13 00 2.9 87.8 of embodiment

800 times 293 238 42 11 20 6.0 74.7 in 24% Methomyl aqua

Contrast 314 154 81 44 11 24 23.7

Annotate: thick line data up and down are respectively the result of field plot trial and the effect of large-area applications in the table.

The laboratory test results of table 3 pair citrus aphid

The Processing Test borer population was checked 48 hours in 24 hours and is checked

(embodiment 1) (head) the dead dead borer population lethality of borer population lethality corrected mortality

460PPM 100 100 100.0 100 100.0 100.0

383PPM 100 98 98.0 100 100.0 100.0

328.6PPM 100 93 93.0 100 100.0 100.0

267.5PPM 100 97 97.0 100 100.0 100.0

255.6PPM 100 84 84.0 90 90.0 89.0

230PPM 100 77 77.0 84 84.0 82.4

Contrast 100 7 7.0 9 9.0

The field test results of table 4 pair citrus aphid

Handle the dead borer population lethality of concentration of treatment investigation borer population corrected mortality

(%) (%) (%) for (head) (head)

Embodiment two 383.3PPM 300 295 98.3 98.2

230PPM 300 289 96.3 96.0

90% desinsection list powder 500PPM 300 267 89.0 88.2

24% Methomyl aqua 300PPM 300 290 96.7 96.5

Contrast 300 20 6.7

The field test results of table 5 pair citrus psylla nymph

The dead borer population lethality of borer population corrected mortality is looked in processing

(embodiment 2) (head) (head) be (%) (%)

383PPM 120 120 100.0 100.0

287.5PPM 120 120 100.0 100.0

230PPM 120 119 99.2 99.2

Blank 120 5 4.2

The field test results of table 6 pair phyllotreta striolata

Handle the borer population insect population of living behind the borer population medicine of living before the medicine rate control efficiency that goes down

(embodiment two) (head/M ²) (head/M ²) (%) (%)

383PPM 36 0 100.0 100.0

287.5PPM 32 0 100.0 100.0

230PPM 39 1 97.4 97.2

Blank 38 35 7.9

The test of table 7 pair cotton aphid and two-spotted spider mite

Cotten aphid control efficiency (%) two-spotted spider mite control efficiency (%) after the processing dispenser

1000 times 1500 times 1000 times 500 times of fates

Embodiment 31 90.3 89.3 90.0 90.0

2 91.4 90.1 90.0 90.0

3 90.4 89.4 90.0 90.0

7 81.9 82.6 80.0 80.0

30% polythiane missible oil 1 70.4 50.2 47.0 30.0

50% dimethyl phenyl carbamate missible oil 1 60.5 42.3 40.0 20.0

Claims (2)

1, a kind of Recompounded agricultural chemical with neires toxin is characterized in that its compositing range (percetage by weight) is:

Sandworm toxin insecticide 5-60

Carbamate insecticide 2-30

Surfactant 1-15

Organic solvent 2-30

The thinner surplus

2, by the described Recompounded agricultural chemical with neires toxin of claim 1, it is characterized in that its compositing range (percetage by weight) is:

Sandworm toxin insecticide 10-20

Carbamate insecticide 5-10

Surfactant 2-8

Organic solvent 5-10

The thinner surplus