CN109172671A - A kind of flue moxibustion traditional Chinese medicine powder and preparation method thereof for kidney yang deficiency syndrome patient - Google Patents

A kind of flue moxibustion traditional Chinese medicine powder and preparation method thereof for kidney yang deficiency syndrome patient Download PDF

Info

Publication number
CN109172671A
CN109172671A CN201811376015.2A CN201811376015A CN109172671A CN 109172671 A CN109172671 A CN 109172671A CN 201811376015 A CN201811376015 A CN 201811376015A CN 109172671 A CN109172671 A CN 109172671A
Authority
CN
China
Prior art keywords
parts
drug
chinese medicine
traditional chinese
decoction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811376015.2A
Other languages
Chinese (zh)
Inventor
赵荣
徐金龙
邢利威
马艳萍
李云秀
袁卓珺
周晓娜
杨泽冠
李莉
黄昆
孙冉
曹加伟
罗成斌
陈颖
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yunnan University of Traditional Chinese Medicine TCM
Original Assignee
Yunnan University of Traditional Chinese Medicine TCM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yunnan University of Traditional Chinese Medicine TCM filed Critical Yunnan University of Traditional Chinese Medicine TCM
Priority to CN201811376015.2A priority Critical patent/CN109172671A/en
Publication of CN109172671A publication Critical patent/CN109172671A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714—Aconitum (monkshood)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/235—Foeniculum (fennel)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/746—Morinda
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/754—Evodia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/55—Liquid-liquid separation; Phase separation

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The flue moxibustion traditional Chinese medicine powder and preparation method thereof that the invention discloses a kind of for kidney yang deficiency syndrome patient, the raw material including following parts by weight: 8~12 parts of radix aconiti lateralis preparata, 3~5 parts of cortex cinnamomi, 2~5 parts of evodia rutaecarpa, 2~6 parts of Morinda officinalis and 1~3 part of fennel seeds.Although the raw material of traditional Chinese medicine powder of the invention is all common Chinese medicinal material, but scientific compatibility through the invention, according to the principle of tcm treatment according to syndrome differentiation, for the cause of disease science preparation of kidney yang deficiency syndrome patient, various types of kidney-yang deficiencies can be treated, by superintending and directing being used cooperatively for moxibustion, not only increase the assimilation effect of drug effect, booster action is played, but also compensates for the defect of moxa-moxibustion physical therapy, clinical practice proof can get extraordinary therapeutic effect.

Description

A kind of flue moxibustion traditional Chinese medicine powder and preparation method thereof for kidney yang deficiency syndrome patient
Technical field
The present invention relates to the medication field for the treatment of kidney yang deficiency syndrome patient, a kind of flue moxibustion Chinese medicines for kidney yang deficiency syndrome patient Powder.
Background technique
Kidney yang deficiency syndrome patient's kidney-yang deficiency, i.e. kidney deficient and weak YANG QI are the diseases of kidney yang-energy failure performance, mostly by ferritic sun Void, or old deficiency of the kidney or prolonged illness be impairment of the kidney and the factors such as sexual strain degree caused by.Clinical manifestation is soreness of waist and knee joint, aversion to cold and cold limbs, Sexual hypoesthesia, tongue nature is fat big, whitish tongue, deeptensepulse；Lassitude, night pollakiuria, edema of lower extremity, shortness of breath and breathe heavily, big loose stool, alopecia Crowd.The drug for treating kidney-yang deficiency currently on the market is more, but curative effect is not very significantly, and therapeutic effect is unobvious, also goes out at present Show some physical therapy methods to assist in the treatment of this kind of illness, treatment cycle is long, slow effect, and the present invention develops a kind of for such The external application Chinese medicine powder of deficiency of kidney-YANG syndrome patient, cooperation is superintended and directed moxibustion, is treated to the ill, very useful to such sufferer.
Summary of the invention
It is an object of the invention to overcome the deficiencies of the prior art and provide in a kind of flue moxibustion for kidney yang deficiency syndrome patient Medicinal powder, dedicated for for various types of kidneys such as soreness of waist and knee joint, aversion to cold and cold limbs, sexual hypoesthesia, the fat big, whitish tongue of tongue nature and deeptensepulses The traditional Chinese medicine powder that deficiency of yang type patient is treated, Transdermal absorption is fast, and good effect, preparation process is simple, and moxibustion is superintended and directed in cooperation, applies to the ill It controls, the absorption of the efficacy of a drug faster more evenly can be made, therapeutic effect can be significantly improved, cure rate reaches 95% or more.
The purpose of the present invention is achieved through the following technical solutions:
A kind of flue moxibustion traditional Chinese medicine powder for kidney yang deficiency syndrome patient, the raw material including following parts by weight:
8~12 parts of radix aconiti lateralis preparata
3~5 parts of cortex cinnamomi
2~5 parts of evodia rutaecarpa
2~6 parts of Morinda officinalis
1~3 part of fennel seeds.
Further, for the flue moxibustion traditional Chinese medicine powder of kidney yang deficiency syndrome patient, the raw material including following parts by weight:
10 parts of radix aconiti lateralis preparata
4 parts of cortex cinnamomi
4 parts of evodia rutaecarpa
3 parts of Morinda officinalis
2 parts of fennel seeds.
A kind of preparation method of the flue moxibustion traditional Chinese medicine powder for kidney yang deficiency syndrome patient, including the following steps:
S1, drug removal of impurities and pretreatment: load weighted radix aconiti lateralis preparata, cortex cinnamomi, evodia rutaecarpa, Morinda officinalis and fennel seeds are removed into impurity elimination Matter is cleaned with pure water respectively, and dry 1~3 hour is spare under conditions of 40~50 DEG C of temperature, by the Wu after being dried It is that 100~300 targeted fine powders are spare that the fruit of medicinal cornel, which is ground into partial size with micronizer, by Morinda officinalis investment 5~10 after drying It is spare that 6~8 hours are impregnated in the white wine of amount again；
S2, extraction: take load weighted radix aconiti lateralis preparata, cortex cinnamomi, fennel seeds mixing, by mixture temperature be 10~25 DEG C of low temperature Lower carry out carbon dioxide abstraction, the pressure of extraction are as follows: 33~36Mpa, the time of extraction are 3~4 hours, CO2Flow be It is stand-by to collect the dregs of a decoction by 200~300L/h；
S3, decoction: the pure water that 5~6 times of amounts are added in the dregs of a decoction extracted in step s 2 impregnates 1~2 hour, reheats and decocts It boils 1.5~2 hours, decoction liquor A is obtained by filtration；
The Morinda officinalis in step S1 after soaking in Chinese liquor is added in decoction liquor A, adds after adding the pure water of 1~2 times of amount Heat decocts the heating of stopping in 1~1.5 hour, and decoction liquor B is obtained by filtration, and the evodia rutaecarpa in step S1 is added in the decoction liquor B Fine powder continues heating 15~30 minutes, and decoction liquor C is obtained by filtration；
S4, purification: the ethyl alcohol that 3 times of amount concentration are 75%~85% being added into decoction liquor C, stirs evenly, and standing 10~ 12 hours, filtering supernatant liquor obtain drug filtrate, will be concentrated into relative density after the ethyl alcohol recycling in the drug filtrate For 1.6~2.0 drug thick paste；
S5, dry cream processed: starch is added in drug thick paste in step s 4, drug extract is uniformly mixing to obtain, by the medicine Object medicinal extract turns round vacuum drying treatment, the condition of the drying through microwave are as follows: 80~85 DEG C of temperature, dry duration is 2~4 small When, obtain drug dry extract；
S6, crushing: the drug dry extract in step S5 is ground into partial size with micronizer and is into 150~200 purposes Traditional Chinese medicine fine powder, then the traditional Chinese medicine fine powder is fitted into glass container and is sealed.
It is the pharmacological property of each raw material of traditional Chinese medicine powder of the invention below:
Radix aconiti lateralis preparata: radix aconiti lateralis preparata is the processed goods of the sub- root of the ranunculaceae plant rhizome of Chinese monkshood, and annual late June to early August excavates, Female root, fibrous root and silt are removed, practises and claims mud monkshood, reduces toxicity, title radix aconiti lateralis preparata after salt marsh, water such as floats, boil, fry at the methods processing； Its nature and flavor is pungent, sweet, big heat；It is toxic, it belongs to the heart, kidney, spleen channel；Cure mainly recuperating depleted yang, mends fire supporing yang, by wind-cold damp pathogen；For yang depletion Collapse, cold weak pulse of limb, impotence, palace cold, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, cold sensation of the genitalia oedema, deficiency of yang diseases caused by external factors and numbness and ache of cold dampness.
Cortex cinnamomi: for skin containing volatile oil (claiming cassia oil) 1~2%, main component is cinnaldehydrum 75~90%, and contains a small amount of acetic acid Cassia bark ester and phenylpropyl acetate, pungent, sweet, the big heat of nature and flavor；Return kidney, spleen, the heart, Liver Channel；It cures mainly mends fire supporing yang, let the fire back to its origin, dissipate Cold analgesic, blood circulation；For impotence, palace cold, waist and knee crymodynia, kidney deficiency characterized by dyspnea, dizziness due to yang deficiency, hot eyes pharyngalgia, trusted subordinate's crymodynia, void Cold vomiting and diarrhoea, cold hernia, renal mass, menostasis and dysmenorrhea.
Evodia rutaecarpa: alias is Wu's cornel, tea is peppery, spicy, nature and flavor: it is arduous, warm, toxic, it is included into Liver Channel, stomach meridian, controls inverse gulp down of vomitting Acid, jueyin headache, cold syndrome in infant vomiting and diarrhoea, abdominal distention, dysmenorrhea, Diarrhoea, vascular hypertension, tinea pedis, hernia, aphthous ulcer, The symptoms such as dentalgia, eczema, impetigo；The pungent scattered hardship of evodia rutaecarpa is let out, the hot dispelling cold of property, and master enters Liver Channel, not only dissipates the cold-evil of Liver Channel, but also soothing the liver The stasis of gas, for the main ingredient for controlling all pains of the liver-cold stagnation of the circulation of vital energy；The pungent scattered hardship of evodia rutaecarpa is let out, the hot dispelling cold of property, and master enters Liver Channel, and it is cold both to have dissipated Liver Channel Heresy, and the stasis of dispersing liver-energy, for the main ingredient for controlling all pains of the liver-cold stagnation of the circulation of vital energy.
Morinda officinalis: containing polysaccharide, amino acid in Morinda officinalis, there are also the elements such as a large amount of potassium, calcium；It is improved immunity and increasing Adding the function of leucocyte, effect is kidney-replenishing, it strengthens the bone, wind-damp dispelling.Control impotence, abdomen crymodynia, urinary incontinence, uterus void it is cold, Wind-cold-dampness arthralgia, soreness of waist and knee joint.
Fennel seeds: fennel seeds acrid flavour, it is warm-natured；Return liver,kidney,spleen, stomach meridian；Primary treatment cold hernia stomachache, the testis swelling and hanging down of either of the testes, pain Through, abdomen crymodynia, abdominal distention, deficiency of food vomiting and diarrhoea；Salt fennel seeds are used for cold hernia stomachache, the testis swelling and hanging down of either of the testes, through illnesss such as cold abdominal pain；It is small Fennel has good curative effect to the uterus cold of insufficiency type caused by cold-dampness, the stagnation of the circulation of vital energy, back crymodynia, tripe distention and fullness in the abdomen, soft stool and hernia etc., Have the function of middle benefit gas, qi-regulating with cortex cinnamomi, agalloch eaglewood, the root of three-nerved spicebush etc..
Target user: soreness of waist and knee joint, aversion to cold and cold limbs, sexual hypoesthesia, tongue nature is fat big, whitish tongue, deeptensepulse；Lassitude, enuresis nocturna Frequency more, edema of lower extremity, shortness of breath and breathe heavily, big loose stool, the crowd of alopecia.
The beneficial effects of the present invention are:
1) traditional Chinese medicine powder Transdermal absorption of the invention is fast, and good effect, preparation process is simple, and moxibustion is superintended and directed in cooperation, treats, can make to the ill The absorption of the efficacy of a drug faster more evenly, can significantly improve therapeutic effect, and cure rate reaches 90% or more.
2) although the raw material of traditional Chinese medicine powder of the invention is all common Chinese medicinal material, scientific compatibility through the invention, root According to the principle of tcm treatment according to syndrome differentiation, is prepared for the cause of disease science of kidney yang deficiency syndrome patient, various types of kidney-yang deficiencies can be treated, led to It crosses and superintends and directs being used cooperatively for moxibustion, not only increase the assimilation effect of drug effect, play booster action, but also compensate for moxa-moxibustion physical therapy Defect, clinical practice proof can get extraordinary therapeutic effect.
3) medicinal powder of the invention is easy to use, it is only necessary to be applied to and superintend and direct moxibustion position, any side effect is not present.
Specific embodiment
Below in conjunction with embodiment, technical solution of the present invention is clearly and completely described, it is clear that described Embodiment is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field Technical staff's every other embodiment obtained under the premise of not making the creative labor belongs to what the present invention protected Range.
The present invention the following technical schemes are provided:
Embodiment 1
A kind of flue moxibustion traditional Chinese medicine powder for kidney yang deficiency syndrome patient, the raw material including following parts by weight:
8 parts of radix aconiti lateralis preparata
3 parts of cortex cinnamomi
2 parts of evodia rutaecarpa
2 parts of Morinda officinalis
1 part of fennel seeds.
The preparation method of flue moxibustion traditional Chinese medicine powder for kidney yang deficiency syndrome patient of the invention, including the following steps:
S1, drug removal of impurities and pretreatment: load weighted radix aconiti lateralis preparata, cortex cinnamomi, evodia rutaecarpa, Morinda officinalis and fennel seeds are removed into impurity elimination Matter is cleaned with pure water respectively, and dry 1 hour is spare under conditions of 40 DEG C of temperature, and the evodia rutaecarpa after being dried is used It is that 100 targeted fine powders are spare that micronizer, which is ground into partial size, Morinda officinalis after drying is put into the white wine of 5 times of amounts and is impregnated 6 hours are spare；
S2, extraction: taking load weighted radix aconiti lateralis preparata, cortex cinnamomi, fennel seeds mixing, by mixture in the case where temperature is 10 DEG C of low temperature into Row carbon dioxide abstraction, the pressure of extraction are as follows: 33Mpa, the time of extraction are 3 hours, CO2Flow be 200L/h, collect The dregs of a decoction are stand-by；
S3, decoction: the pure water that 5 times of amounts are added in the dregs of a decoction extracted in step s 2 impregnates 1 hour, reheats and decocts 1.5 Hour, decoction liquor A is obtained by filtration；
The Morinda officinalis in step S1 after soaking in Chinese liquor is added in decoction liquor A, heating is decocted after adding the pure water of 1 times of amount The heating of stopping in 1 hour is boiled, decoction liquor B is obtained by filtration, the evodia rutaecarpa fine powder in step S1 is added in the decoction liquor B, continues Heating 15 minutes, is obtained by filtration decoction liquor C；
S4, purification: the ethyl alcohol that 3 times of amount concentration are 75% is added into decoction liquor C, stirs evenly, stands 10 hours, mistake Filter supernatant liquor obtains drug filtrate, will be concentrated into the drug that relative density is 1.6 after the ethyl alcohol recycling in the drug filtrate Thick paste；
S5, dry cream processed: starch is added in drug thick paste in step s 4, drug extract is uniformly mixing to obtain, by the medicine Object medicinal extract turns round vacuum drying treatment, the condition of the drying through microwave are as follows: 80 DEG C of temperature, dry 2 hours of duration, obtains medicine Object dry extract；
S6, crushing: by the drug dry extract in step S5 with micronizer be ground into partial size be into 150 mesh Chinese medicine it is thin Powder, then the traditional Chinese medicine fine powder is fitted into glass container and is sealed.
Embodiment 2
A kind of flue moxibustion traditional Chinese medicine powder for kidney yang deficiency syndrome patient, the raw material including following parts by weight:
12 parts of radix aconiti lateralis preparata
5 parts of cortex cinnamomi
5 parts of evodia rutaecarpa
6 parts of Morinda officinalis
3 parts of fennel seeds.
The preparation method of flue moxibustion traditional Chinese medicine powder for kidney yang deficiency syndrome patient of the invention, including the following steps:
S1, drug removal of impurities and pretreatment: load weighted radix aconiti lateralis preparata, cortex cinnamomi, evodia rutaecarpa, Morinda officinalis and fennel seeds are removed into impurity elimination Matter is cleaned with pure water respectively, and dry 3 hours are spare under conditions of temperature 50 C, and the evodia rutaecarpa after being dried is used Micronizer is ground into that the fine powder that partial size is 300 is spare, and Morinda officinalis after drying is put into the white wine of 10 times of amounts and impregnate 8 A hour is spare；
S2, extraction: taking load weighted radix aconiti lateralis preparata, cortex cinnamomi, fennel seeds mixing, by mixture in the case where temperature is 25 DEG C of low temperature into Row carbon dioxide abstraction, the pressure of extraction are as follows: 36Mpa, the time of extraction are 4 hours, CO2Flow be 300L/h, collect The dregs of a decoction are stand-by；
S3, decoction: the pure water that 6 times of amounts are added in the dregs of a decoction extracted in step s 2 impregnates 2 hours, and it is small to reheat decoction 2 When, decoction liquor A is obtained by filtration；
The Morinda officinalis in step S1 after soaking in Chinese liquor is added in decoction liquor A, heating is decocted after adding the pure water of 2 times of amounts The heating of stopping in 1.5 hours is boiled, decoction liquor B is obtained by filtration, the evodia rutaecarpa fine powder in step S1 is added in the decoction liquor B, after Continuous heating 30 minutes, is obtained by filtration decoction liquor C；
S4, purification: the ethyl alcohol that 3 times of amount concentration are 85% is added into decoction liquor C, stirs evenly, stands 12 hours, mistake Filter supernatant liquor obtains drug filtrate, will be concentrated into the drug that relative density is 2.0 after the ethyl alcohol recycling in the drug filtrate Thick paste；
S5, dry cream processed: starch is added in drug thick paste in step s 4, drug extract is uniformly mixing to obtain, by the medicine Object medicinal extract turns round vacuum drying treatment, the condition of the drying through microwave are as follows: 85 DEG C of temperature, dry 4 hours of duration, obtains medicine Object dry extract；
S6, crushing: by the drug dry extract in step S5 with micronizer be ground into partial size be into 200 mesh Chinese medicine it is thin Powder, then the traditional Chinese medicine fine powder is fitted into glass container and is sealed.
Embodiment 3
A kind of flue moxibustion traditional Chinese medicine powder for kidney yang deficiency syndrome patient, the raw material including following parts by weight:
10 parts of radix aconiti lateralis preparata
4 parts of cortex cinnamomi
4 parts of evodia rutaecarpa
3 parts of Morinda officinalis
2 parts of fennel seeds.
The preparation method of flue moxibustion traditional Chinese medicine powder for kidney yang deficiency syndrome patient of the invention, including the following steps:
S1, drug removal of impurities and pretreatment: load weighted radix aconiti lateralis preparata, cortex cinnamomi, evodia rutaecarpa, Morinda officinalis and fennel seeds are removed into impurity elimination Matter is cleaned with pure water respectively, and dry 2 hours are spare under conditions of temperature 45 C, and the evodia rutaecarpa after being dried is used Micronizer is ground into that the fine powder that partial size is 200 is spare, and Morinda officinalis after drying is put into the white wine of 7 times of amounts and impregnate 7 A hour is spare；
S2, extraction: taking load weighted radix aconiti lateralis preparata, cortex cinnamomi, fennel seeds mixing, by mixture in the case where temperature is 18 DEG C of low temperature into Row carbon dioxide abstraction, the pressure of extraction are as follows: 35Mpa, the time of extraction are 3.5 hours, CO2Flow be 250L/h, receive It is stand-by to collect the dregs of a decoction；
S3, decoction: the pure water that 5.5 times of amounts are added in the dregs of a decoction extracted in step s 2 impregnates 1.5 hours, reheats and decocts 1.8 hours, decoction liquor A is obtained by filtration；
The Morinda officinalis in step S1 after soaking in Chinese liquor is added in decoction liquor A, is heated after adding the pure water of 1.5 times of amounts The heating of stopping in 1.2 hours is decocted, decoction liquor B is obtained by filtration, the evodia rutaecarpa fine powder in step S1 is added in the decoction liquor B, Continue heating 25 minutes, decoction liquor C is obtained by filtration；
S4, purification: the ethyl alcohol that 3 times of amount concentration are 80% is added into decoction liquor C, stirs evenly, stands 11 hours, mistake Filter supernatant liquor obtains drug filtrate, will be concentrated into the drug that relative density is 1.8 after the ethyl alcohol recycling in the drug filtrate Thick paste；
S5, dry cream processed: starch is added in drug thick paste in step s 4, drug extract is uniformly mixing to obtain, by the medicine Object medicinal extract turns round vacuum drying treatment, the condition of the drying through microwave are as follows: 82 DEG C of temperature, dry 3 hours of duration, obtains medicine Object dry extract；
S6, crushing: by the drug dry extract in step S5 with micronizer be ground into partial size be into 180 mesh Chinese medicine it is thin Powder, then the traditional Chinese medicine fine powder is fitted into glass container and is sealed.
Embodiment 4
A kind of flue moxibustion traditional Chinese medicine powder for kidney yang deficiency syndrome patient, the raw material including following parts by weight:
9 parts of radix aconiti lateralis preparata
3 parts of cortex cinnamomi
5 parts of evodia rutaecarpa
3 parts of Morinda officinalis
2 parts of fennel seeds.
The preparation method of flue moxibustion traditional Chinese medicine powder for kidney yang deficiency syndrome patient of the invention, including the following steps:
S1, drug removal of impurities and pretreatment: load weighted radix aconiti lateralis preparata, cortex cinnamomi, evodia rutaecarpa, Morinda officinalis and fennel seeds are removed into impurity elimination Matter is cleaned with pure water respectively, and dry 1.5 hours are spare under conditions of 42 DEG C of temperature, by the evodia rutaecarpa after being dried It is ground into that the fine powder that partial size is 220 is spare with micronizer, Morinda officinalis after drying is put into the white wine of 7 times of amounts and be impregnated 6.5 hours are spare；
S2, extraction: taking load weighted radix aconiti lateralis preparata, cortex cinnamomi, fennel seeds mixing, by mixture in the case where temperature is 19 DEG C of low temperature into Row carbon dioxide abstraction, the pressure of extraction are as follows: 34Mpa, the time of extraction are 3.2 hours, CO2Flow be 260L/h, receive It is stand-by to collect the dregs of a decoction；
S3, decoction: the pure water that 5.6 times of amounts are added in the dregs of a decoction extracted in step s 2 impregnates 1.6 hours, reheats and decocts 1.8 hours, decoction liquor A is obtained by filtration；
The Morinda officinalis in step S1 after soaking in Chinese liquor is added in decoction liquor A, is heated after adding the pure water of 1.5 times of amounts The heating of stopping in 1.3 hours is decocted, decoction liquor B is obtained by filtration, the evodia rutaecarpa fine powder in step S1 is added in the decoction liquor B, Continue heating 26 minutes, decoction liquor C is obtained by filtration；
S4, purification: the ethyl alcohol that 3 times of amount concentration are 82% being added into decoction liquor C, stirs evenly, stands 11.5 hours, Filtering supernatant liquor obtains drug filtrate, will be concentrated into the medicine that relative density is 1.8 after the ethyl alcohol recycling in the drug filtrate Object thick paste；
S5, dry cream processed: starch is added in drug thick paste in step s 4, drug extract is uniformly mixing to obtain, by the medicine Object medicinal extract turns round vacuum drying treatment, the condition of the drying through microwave are as follows: 82 DEG C of temperature, dry 3 hours of duration, obtains medicine Object dry extract；
S6, crushing: by the drug dry extract in step S5 with micronizer be ground into partial size be into 170 mesh Chinese medicine it is thin Powder, then the traditional Chinese medicine fine powder is fitted into glass container and is sealed.
Embodiment 5
A kind of flue moxibustion traditional Chinese medicine powder for kidney yang deficiency syndrome patient, the raw material including following parts by weight:
11 parts of radix aconiti lateralis preparata
5 parts of cortex cinnamomi
3 parts of evodia rutaecarpa
5 parts of Morinda officinalis
1 part of fennel seeds.
The preparation method of flue moxibustion traditional Chinese medicine powder for kidney yang deficiency syndrome patient of the invention, including the following steps:
S1, drug removal of impurities and pretreatment: load weighted radix aconiti lateralis preparata, cortex cinnamomi, evodia rutaecarpa, Morinda officinalis and fennel seeds are removed into impurity elimination Matter is cleaned with pure water respectively, and dry 2.5 hours are spare under conditions of 46 DEG C of temperature, by the evodia rutaecarpa after being dried It is ground into that the fine powder that partial size is 280 is spare with micronizer, Morinda officinalis after drying is put into the white wine of 9 times of amounts and be impregnated 7 hours are spare；
S2, extraction: taking load weighted radix aconiti lateralis preparata, cortex cinnamomi, fennel seeds mixing, by mixture in the case where temperature is 22 DEG C of low temperature into Row carbon dioxide abstraction, the pressure of extraction are as follows: 35Mpa, the time of extraction are 3.8 hours, CO2Flow be 270L/h, receive It is stand-by to collect the dregs of a decoction；
S3, decoction: the pure water that 5.6 times of amounts are added in the dregs of a decoction extracted in step s 2 impregnates 1.9 hours, reheats and decocts 1.6 hours, decoction liquor A is obtained by filtration；
The Morinda officinalis in step S1 after soaking in Chinese liquor is added in decoction liquor A, heating is decocted after adding the pure water of 2 times of amounts The heating of stopping in 12 hours is boiled, decoction liquor B is obtained by filtration, the evodia rutaecarpa fine powder in step S1 is added in the decoction liquor B, continues Heating 28 minutes, is obtained by filtration decoction liquor C；
S4, purification: the ethyl alcohol that 3 times of amount concentration are 79% being added into decoction liquor C, stirs evenly, stands 11.5 hours, Filtering supernatant liquor obtains drug filtrate, will be concentrated into the medicine that relative density is 1.7 after the ethyl alcohol recycling in the drug filtrate Object thick paste；
S5, dry cream processed: starch is added in drug thick paste in step s 4, drug extract is uniformly mixing to obtain, by the medicine Object medicinal extract turns round vacuum drying treatment, the condition of the drying through microwave are as follows: 83 DEG C of temperature, dry 3.5 hours of duration, obtains Drug dry extract；
S6, crushing: by the drug dry extract in step S5 with micronizer be ground into partial size be into 180 mesh Chinese medicine it is thin Powder, then the traditional Chinese medicine fine powder is fitted into glass container and is sealed.
The clinical practice observations of traditional Chinese medicine powder of the present invention:
1. clinical case:
It selects in March, 2016 to the outpatient service of in August, 2018 to meet 200 patients of kidney-yang deficiency diagnostic criteria, is randomly divided into Two groups: treatment group 100, control group 100；Wherein male to female ratio each 50%, two groups of patient ages, gender, the course of disease and symptom Light and heavy degree etc. is comparable through statistical analysis, no significant difference (P > 0.05).
2. diagnostic criteria:
" guideline of clinical investigations of new Chinese medicine treatment kidney-yang deficiency " promulgated referring to the Ministry of Public Health:
Primary symptom: soreness of waist and knee joint, aversion to cold and cold limbs, sexual hypoesthesia, tongue nature is fat big, whitish tongue, deeptensepulse；
Minor symptom: lassitude, night pollakiuria, edema of lower extremity, shortness of breath and breathe heavily, big loose stool, alopecia.
Have the above primary symptom 2, minor symptom 2, i.e., diagnosable syndrome of deficiency of kidney yang.
3. exclusion criteria:
(1) standard of being included in is not met, there is obvious and folder card or merges card person；
(2) age is in under-18s over-65s, gestation or breast feeding women, allergic constitution and those who are allergic to this drug；
(3) the severe primaries disease such as angiocarpy, the cerebrovascular, liver, kidney, hemopoietic system, mental patient are associated with；
(4) unconsciousness, subjective malaise symptoms cannot be expressed, with serious depression and anxiety symptom or mental disease person；
(5) progressivity malignant tumour or other serious deelines, easy concurrent infection and bleeder；Merging angiocarpy, The primary diseases persons such as liver, kidney, digestion, hemopoietic system:
(6) ray of teratogenesis amount, poisonous substance, drug were contacted and is in action period or there are the bad habits such as excessive drinking, drug abuse；
(7) compliance is poor, refusal participates in testing or be reluctant to sign informed consent form and follow-up is difficult, can not judge curative effect, Or data is not congruent affects the treatment or safety judgement person.
4. treatment method:
The traditional Chinese medicine powder that treatment group is prepared using the embodiment of the present invention 3 superintends and directs moxibustion method using conventional, smears superintending and directing moxibustion position Medicinal powder of the invention was superintended and directed every time in moxibustion half an hour, and treatment in every 5 days is primary, and 6 times as a treatment course, treats 2 courses for the treatment of, control group is not Using medicinal powder of the invention, only with superintending and directing moxibustion.
5. curative effect determinate standard:
(1) cure: symptom, the sign of kidney-yang deficiency disappear, and disease integration reduces >=95%；
(2) effective: symptom, the sign of kidney-yang deficiency are obviously improved, and disease integration reduces >=70%；
(3) effectively: the symptom of kidney-yang deficiency, sign take a favorable turn, and disease integration reduces >=30%；
(4) invalid: the symptom of kidney-yang deficiency, sign are reduced without improvement, disease integration less than 30%.
Calculation formula (Nimodipine method) are as follows: ((pre-treatment score-post treatment integral)/pre-treatment score) × 100%.
6. treatment results:
The different group efficacy result statistics of table 1
Clinical recovery 57 in 100 patients for the treatment of group, cure rate 57%；Effective 24, obvious effective rate 24%；Effective 10 Example, effective percentage 10%；Total effective rate is up to 91.%.
Clinical recovery 38 in 100 patients of control group, cure rate 38%；Effective 21, obvious effective rate 21%；Effective 17 Example.Effective percentage 17%；Total effective rate is up to 76%.
By result above as can be seen that traditional Chinese medicine powder of the invention is by superintending and directing the cooperation of moxibustion, compared to not having to drug of the present invention It treats, total effective rate is higher by 25%, illustrate that traditional Chinese medicine powder Transdermal absorption of the invention is fast, good effect, while its preparation process letter Single, moxibustion is superintended and directed in cooperation, is treated to the ill, can be made the absorption of the efficacy of a drug faster more evenly, can significantly improve therapeutic effect, cure rate reaches 90% or more.
Although the raw material of traditional Chinese medicine powder of the invention is all common Chinese medicinal material, scientific compatibility through the invention, according to The principle of tcm treatment according to syndrome differentiation prepares for the cause of disease science of kidney yang deficiency syndrome patient, can treat various types of kidney-yang deficiencies, pass through With superintend and direct being used cooperatively for moxibustion, not only increase the assimilation effect of drug effect, play booster action, but also compensate for moxa-moxibustion physical therapy Defect, clinical practice proof can get extraordinary therapeutic effect.
The above is only a preferred embodiment of the present invention, it should be understood that the present invention is not limited to described herein Form should not be regarded as an exclusion of other examples, and can be used for other combinations, modifications, and environments, and can be at this In the text contemplated scope, modifications can be made through the above teachings or related fields of technology or knowledge.And those skilled in the art institute into Capable modifications and changes do not depart from the spirit and scope of the present invention, then all should be in the protection scope of appended claims of the present invention It is interior.

Claims (3)

1. a kind of flue moxibustion traditional Chinese medicine powder for kidney yang deficiency syndrome patient, which is characterized in that the raw material including following parts by weight:
8~12 parts of radix aconiti lateralis preparata
3~5 parts of cortex cinnamomi
2~5 parts of evodia rutaecarpa
2~6 parts of Morinda officinalis
1~3 part of fennel seeds.
2. the flue moxibustion traditional Chinese medicine powder according to claim 1 for kidney yang deficiency syndrome patient, which is characterized in that including following heavy Measure the raw material of part:
10 parts of radix aconiti lateralis preparata
4 parts of cortex cinnamomi
4 parts of evodia rutaecarpa
3 parts of Morinda officinalis
2 parts of fennel seeds.
3. the preparation method for the flue moxibustion traditional Chinese medicine powder of kidney yang deficiency syndrome patient, feature exist as claimed in claim 1 or 2 In, including the following steps:
S1, drug removal of impurities and pretreatment: removing impurity for load weighted radix aconiti lateralis preparata, cortex cinnamomi, evodia rutaecarpa, Morinda officinalis and fennel seeds, It is cleaned respectively with pure water, dry 1~3 hour is spare under conditions of 40~50 DEG C of temperature, by the Wu Zhu after being dried It is that 100~300 targeted fine powders are spare that cornel, which is ground into partial size with micronizer, and Morinda officinalis after drying is put into 5~10 times It is spare that 6~8 hours are impregnated in the white wine of amount；
S2, extraction: taking load weighted radix aconiti lateralis preparata, cortex cinnamomi, fennel seeds mixing, by mixture in the case where temperature is 10~25 DEG C of low temperature into Row carbon dioxide abstraction, the pressure of extraction are as follows: 33~36Mpa, the time of extraction are 3~4 hours, CO2Flow be 200~ It is stand-by to collect the dregs of a decoction by 300L/h；
S3, decoction: the pure water that 5~6 times of amounts are added in the dregs of a decoction extracted in step s 2 impregnates 1~2 hour, reheats and decocts 1.5~2 hours, decoction liquor A is obtained by filtration；
The Morinda officinalis in step S1 after soaking in Chinese liquor is added in decoction liquor A, heating is decocted after adding the pure water of 1~2 times of amount The heating of stopping in 1~1.5 hour is boiled, decoction liquor B is obtained by filtration, the evodia rutaecarpa fine powder in step S1 is added in the decoction liquor B, Continue heating 15~30 minutes, decoction liquor C is obtained by filtration；
S4, purification: the ethyl alcohol that 3 times of amount concentration are 75%~85% is added into decoction liquor C, stirs evenly, stands 10~12 small When, filtering supernatant liquor obtain drug filtrate, by the drug filtrate ethyl alcohol recycling after be concentrated into relative density be 1.6~ 2.0 drug thick paste；
S5, dry cream processed: starch is added in drug thick paste in step s 4, is uniformly mixing to obtain drug extract, the drug is soaked Cream turns round vacuum drying treatment, the condition of the drying through microwave are as follows: 80~85 DEG C of temperature, dry 2~4 hours of duration, obtains To drug dry extract；
S6, crushing: the drug dry extract in step S5 is ground into the Chinese medicine that partial size is into 150~200 mesh with micronizer Fine powder, then the traditional Chinese medicine fine powder is fitted into glass container and is sealed.
CN201811376015.2A 2018-11-19 2018-11-19 A kind of flue moxibustion traditional Chinese medicine powder and preparation method thereof for kidney yang deficiency syndrome patient Pending CN109172671A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811376015.2A CN109172671A (en) 2018-11-19 2018-11-19 A kind of flue moxibustion traditional Chinese medicine powder and preparation method thereof for kidney yang deficiency syndrome patient

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811376015.2A CN109172671A (en) 2018-11-19 2018-11-19 A kind of flue moxibustion traditional Chinese medicine powder and preparation method thereof for kidney yang deficiency syndrome patient

Publications (1)

Publication Number Publication Date
CN109172671A true CN109172671A (en) 2019-01-11

Family

ID=64939927

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811376015.2A Pending CN109172671A (en) 2018-11-19 2018-11-19 A kind of flue moxibustion traditional Chinese medicine powder and preparation method thereof for kidney yang deficiency syndrome patient

Country Status (1)

Country Link
CN (1) CN109172671A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111388646A (en) * 2020-05-21 2020-07-10 极臣生物科技(深圳)有限公司 Traditional Chinese medicine composition for improving male sexual function and preparation method and application thereof
CN114903950A (en) * 2022-06-29 2022-08-16 南充市中医医院 A pharmaceutical composition for improving male hyposexuality

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106822740A (en) * 2017-01-19 2017-06-13 郭花良 Beauty Traditional Chinese medicine external preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106822740A (en) * 2017-01-19 2017-06-13 郭花良 Beauty Traditional Chinese medicine external preparation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
林海波等: "督灸治疗脾肾阳虚型绝经后骨质疏松症患者腰背痛的临床研究", 《中医临床研究》 *
王艳等: "刘平夫教授运用附子的经验", 《长春中医药大学学报》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111388646A (en) * 2020-05-21 2020-07-10 极臣生物科技(深圳)有限公司 Traditional Chinese medicine composition for improving male sexual function and preparation method and application thereof
CN114903950A (en) * 2022-06-29 2022-08-16 南充市中医医院 A pharmaceutical composition for improving male hyposexuality

Similar Documents

Publication Publication Date Title
CN104666698A (en) External-use traditional Chinese medicine ointment for treating gonarthromeningitis and preparation method of traditional Chinese medicine ointment
CN109172671A (en) A kind of flue moxibustion traditional Chinese medicine powder and preparation method thereof for kidney yang deficiency syndrome patient
CN112274621A (en) Cold-dispelling uterus-warming plant herbal paste and preparation method thereof
CN104161864A (en) External-use plaster for tonifying spleen and tonifying stomach and preparation method thereof
CN103463467B (en) A kind of seedling prescription wine with nourishing kidney yin
CN104906551B (en) A kind of anti-fatigue Chinese medicinal composition and preparation method
CN101116732A (en) Chinese traditional medicine composition for treating neurodermatitis
CN103131612A (en) Traditional Chinese medicine health-care wine for aged people and preparation method thereof
CN103432426B (en) Traditional Chinese medicinal tablets for treating neuralgic amyotrophy and preparation method thereof
CN105920130A (en) Preparation method and externally used ointment of traditional Chinese medicine for treating talalgia
CN106109925A (en) A kind of Chinese medicine decoction for treating constipation
CN104352737A (en) Traditional Chinese medicinal preparation for treating rheumatic low back and leg pain
CN104958722A (en) Dampness removing and arthralgia dispelling wine
CN104645063A (en) Pills for treating hyperplasia of mammary glands and preparation method thereof
CN104189809A (en) Cold-dispelling tendon-relaxing pain-relieving liquor
CN104224946B (en) A kind of pharmaceutical composition for the treatment of deficiency of the liver and kindey
CN102626503B (en) Chinese medicinal oral liquid for smoothing heart and enhancing intelligence
CN101496885B (en) Chinese herbal medicine preparation for treating tumor
CN105878985A (en) Semen hyoscyami and cortex phellodendri traditional Chinese medicine hot-compress salt bag and preparing method
CN105596584A (en) Traditional Chinese medicine preparation special for local anesthesia and preparation method thereof
CN104258110B (en) A kind of Chinese medicine for treating cardioneurosis
CN104547999A (en) Oil for postpartum sweating
CN109172636A (en) A kind of external-applied ointment and preparation method thereof for Patients with Kidney-Yang Deficiency Syndrome
CN103432452A (en) Preparation method for traditional Chinese medicine for treating chili adephagia-type acute cervical lymphnoditis
CN103536883B (en) The Chinese medicine for the treatment of heart kidney qi Yin bivacuity pattern of syndrome spleen fatiguing disease

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20190111

RJ01 Rejection of invention patent application after publication