CN109172514A - A kind of skin care item and preparation method thereof of moisturizing anti-aging - Google Patents
A kind of skin care item and preparation method thereof of moisturizing anti-aging Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The present invention provides a kind of skin care item and preparation method thereof of moisturizing anti-aging, the skin care item of the moisturizing anti-aging, cosmetics are prepared using white Flos Plumeriae Acutifoliae extract, dragon's blood resin, Herb Gynostemmae Pentaphylli extract, American-cockroach-extract, hippophae rhamnoides fruit oil and Rosemary Oil, refined jasmine oil as raw material, each raw material has good cooperative effect, can not only invigorate blood circulation beauty treatment, improve skin complexion, and it has a significant effect in terms of anti-aging, anti-oxidant, moisturizing, elasticity of skin can be effectively promoted, keeps skin exquisiteness glossy.
Description
Technical field
The present invention relates to daily cosmetics technical fields, a kind of skin care item in particular to moisturizing anti-aging and its
Preparation method.
Background technique
Frangipanis (Plumeria rubra L.cv.Acutifolia), alias yolk flower are spent in big season, are oleander
Section belongs to machaka or dungarunga.Cold boiled chicken egg flower is one kind of numerous kinds.It is advanced for manufacturing that Cold boiled chicken egg flower can extract essence
Cosmetic, perfumed soap and food additives are used, and price is quite high, great business development potentiality;Frangipanis can be used as after drying and doing
A herb has clearing away summerheat, moistening lung throat soothing throat, can also treat the diseases such as have sore throat.It often will be white in In Guangdong Province
Frangipanis dry and make antipyretic beverage, be popular.
With the increase at age, the endogenous anti-oxidative system activity for removing free radical in vivo declines, and ultraviolet irradiation, life
Pressure, the factors such as all night, electromagnetic radiation of staying up late of living are easy to cause human body to generate a large amount of free radical.When clear more than interior free yl
Except system Scavenging activity when, arriving leads to internal oxygen radical (ROS) bulk deposition.ROS acts on epidermal cell, can cause
The oxidation of DNA, protein and lipid etc. reoxidizes damage, destroys the integrality of eucaryotic cell structure and function, causes epidermal cell
Oxidativestress damage leads to the aging of skin.The main feature of human skin aging has: there is wrinkle, flexibility decrease, color in skin
Element deposition, water holding capacity decline etc..
Existing anti-ageing skin care item mostly use expensive industrial chemicals, are not suitable for public use, or even will cause skin and bear
Load.With the improvement of living standards, requirement of the people to anti-aging cosmetics and skincare product is also higher and higher, natural no stimulation is emphasized,
Safety is without side-effects.
In view of this, the present invention is specifically proposed.
Summary of the invention
The first object of the present invention is to provide a kind of skin care item of moisturizing anti-aging, described to solve the above problems
The skin care item of moisturizing anti-aging, by white Flos Plumeriae Acutifoliae extract, dragon's blood resin, Herb Gynostemmae Pentaphylli extract, American-cockroach-extract, sea-buckthorn
Fruit oil and Rosemary Oil, refined jasmine oil prepare cosmetics as raw material, and each raw material has good cooperative effect, not only can be with
Promoting blood circulation beauty treatment, improves skin complexion, and have a significant effect in terms of anti-aging, anti-oxidant, moisturizing, can effectively promote flesh
Skin elasticity, keeps skin exquisiteness glossy.
The second object of the present invention is to provide the preparation method of the skin care item of moisturizing anti-aging described in one kind, this method
Raw material is mixed, have many advantages, such as it is convenient, simple, be readily produced.
In order to realize above-mentioned purpose of the invention, the following technical scheme is adopted:
A kind of skin care item of moisturizing anti-aging, including the following components according to mass fraction meter:
White Flos Plumeriae Acutifoliae extract 1-5 parts, 0.5-5 parts of dragon's blood resin, 0.1-3 parts of Herb Gynostemmae Pentaphylli extract, American cockroach is extracted
0.01-2.0 parts of object, 3-8 parts of hippophae rhamnoides fruit oil, 0.1-1.5 parts of Rosemary Oil, 0.05-1 parts of refined jasmine oil and water 32.27-
62.47 parts.
Preferably, the Herb Gynostemmae Pentaphylli extract is the water extract of gynostemma pentaphylla.
Preferably, the American-cockroach-extract is the alcohol extract of American cockroach.
Preferably, the wet concentration is from one of deionized water, pure water and drinking water or several combinations.
Preferably, the skin care item of the moisturizing anti-aging, including the following components according to mass fraction meter:
White Flos Plumeriae Acutifoliae extract 2-4 parts, 1-3 parts of dragon's blood resin, 0.5-2 parts of Herb Gynostemmae Pentaphylli extract, American-cockroach-extract
0.5-1.5 parts, 4-6 parts of hippophae rhamnoides fruit oil, 0.5-1 parts of Rosemary Oil, 0.2-0.8 parts and water 40-56.3 parts of refined jasmine oil.
Preferably, in terms of mass fraction, further includes: 3-15 parts of emulsifier;It is furthermore preferred that the emulsifier is hard selected from glycerol
In resin acid ester, cetostearyl alcohol, dimethyl silicone polymer, polyethylene glycol -14M, docosyl alcohol polyethers -25 and stereth -21
One or more of combinations.
Preferably, in terms of mass fraction, further includes: thickener 0.1-2 parts of film forming;It is furthermore preferred that the film forming thickener
Selected from one or more of Sodium Polyacrylate, carbomer, hydroxyethyl cellulose, galactolipin araban and polyvinyl alcohol
Combination.
Preferably, in terms of mass fraction, further includes: 0.3-0.5 parts of preservative;It is furthermore preferred that the preservative is selected from benzene
One of oxyethanol, DMDM hydantoin, methyl hydroxybenzoate, Nipasol, methylisothiazolinone and parahydroxyacet-ophenone or
Several combinations.
Preferably, in terms of mass fraction, further includes: 3-5 parts of moisturizer;It is furthermore preferred that the moisturizer be selected from propylene glycol,
The combination of one or more of glycerol, allantoin, Sodium Hyaluronate, trehalose and 1,3 butanediols.
Preferably, the white Flos Plumeriae Acutifoliae extract is the ethanol extract of Cold boiled chicken egg flower;It is furthermore preferred that the Cold boiled chicken egg flower
For Cold boiled chicken egg flower of the fresh picking after drying and doing.
Preferably, the preparation method of the ethanol extract of the Cold boiled chicken egg flower, specifically includes the following steps:
The Cold boiled chicken egg flower of fresh picking is dried, is crushed, ethyl alcohol is added and impregnates smashed Cold boiled chicken egg flower, after immersion
Cold boiled chicken egg flower carries out refluxing extraction 3-4 times, and merging filtrate after ethyl alcohol is recovered under reduced pressure, obtains the ethanol extract of the Cold boiled chicken egg flower.
Preferably, the Cold boiled chicken egg flower dried is crushed to partial size less than 60 mesh by the step of crushing.
Preferably, the quality of the ethyl alcohol is 8-12 times of the Cold boiled chicken egg flower quality after drying, it is furthermore preferred that the ethyl alcohol
Mass concentration be 85%-95%.
Preferably, the temperature of the immersion is 55-65 DEG C, it is furthermore preferred that the time of the immersion is 2-3 hours.
Preferably, the temperature of the refluxing extraction is 70-75 DEG C;It is furthermore preferred that the time of the refluxing extraction is every time
1-1.5 hour.
The preparation method of the skin care item of the moisturizing anti-aging, comprising the following steps:
By white Flos Plumeriae Acutifoliae extract, dragon's blood resin, Herb Gynostemmae Pentaphylli extract, American-cockroach-extract, 3-8 parts of hippophae rhamnoides fruit oil,
Rosemary Oil and refined jasmine oil are dissolved in water, and emulsifier, film forming thickener, preservative and moisturizer is being added, is obtaining the moisturizing
The skin care item of anti-aging.
Compared with prior art, the invention has the benefit that
(1) skin care item of moisturizing anti-aging provided by the present invention, are prepared by natural plant active component, safe nothing
Toxic side effect is particularly suitable for the nursing of anaphylaxis skin, has effects that invigorate blood circulation beauty treatment, anti-aging and moisturizing, can promote flesh
Skin elasticity and gloss, keep skin more fine and smooth compact.
(2) preparation method of the skin care item of moisturizing anti-aging provided by the present invention, it is convenient, simple, it is easy to high-volume quotient
Industry metaplasia produces.
Specific embodiment
Technical solution of the present invention is clearly and completely described below in conjunction with specific embodiment, but ability
Field technique personnel will be understood that following described embodiments are some of the embodiments of the present invention, instead of all the embodiments,
It is merely to illustrate the present invention, and is not construed as limiting the scope of the invention.Based on the embodiments of the present invention, the common skill in this field
Art personnel every other embodiment obtained without making creative work belongs to the model that the present invention protects
It encloses.The person that is not specified actual conditions in embodiment, carries out according to conventional conditions or manufacturer's recommended conditions.Agents useful for same or instrument
Production firm person is not specified, is the conventional products that can be obtained by commercially available purchase.
A kind of skin care item of moisturizing anti-aging, including the following components according to mass fraction meter:
White Flos Plumeriae Acutifoliae extract 1-5 parts, 0.5-5 parts of dragon's blood resin, 0.1-3 parts of Herb Gynostemmae Pentaphylli extract, American cockroach is extracted
0.01-2.0 parts of object, 3-8 parts of hippophae rhamnoides fruit oil, 0.1-1.5 parts of Rosemary Oil, 0.05-1 parts of refined jasmine oil and water 32.27-
62.47 parts.
White Flos Plumeriae Acutifoliae extract, dragon's blood resin, Herb Gynostemmae Pentaphylli extract can remove free radical, provide skin nutrition, have
Anti-aging, the activity for improving skin water retention.American-cockroach-extract, hippophae rhamnoides fruit oil can preferably penetrate into skin base layer,
Impaired flesh floor cells are effectively repaired, cell viability is enhanced, increase the ability that flesh floor cells independently absorb nutritional ingredient, realize flesh
The autonomous anti-aging of skin.Rosemary Oil, refined jasmine oil can moisturize the skin, and be effectively protected to skin offer.
Hippophae rhamnoides fruit oil is squeezing method acquisition.On skin effect, sea-buckthorn has the work of anti-inflammatory myogenic, promotion regeneration
With, it is rich in VE, carrotene, carotenoid, β-sitosterol, unsaturated fatty acid etc., can help skin metabolism,
Anti-inflammatory, promotion ulcer healing effect.In addition, it contains the ingredients such as multivitamin, microelement, unsaturated fatty acid, it can be light
Change senile plaque, chloasma, it is all effective to skin aging etc. is prevented.
Rosemary Oil and refined jasmine oil are way of distillation acquisition.Rosemary Oil has very strong astriction, tightens relaxation
Skin, also can reduce congested, swelling;Its stronger astriction, the convergence for skin after weight-reducing, allows skin consolidation to have bullet
Property.The effect of Rosemary Oil stimulates is particularly helpful scalp imbalance, can improve dandruff and stimulate hair growth.Jasmine essence
Oil has conditioning dry and sensitivity skin, increases skin elasticity and draws.Refined jasmine oil can also improve reproductive system, promote milk point
It secretes, the regeneration of Skin Cell can be promoted, have extraordinary compact effect to skin, and there is certain lightening effect.
Present inventor is by a large amount of the study found that white Flos Plumeriae Acutifoliae extract, dragon's blood resin, gynostemma pentaphylla are extracted
Object, American-cockroach-extract, hippophae rhamnoides fruit oil and Rosemary Oil, refined jasmine oil prepare cosmetics as raw material, and each raw material has
Good cooperative effect, can not only invigorate blood circulation beauty treatment, improve skin complexion, and have in terms of anti-aging, anti-oxidant, moisturizing
Apparent effect can effectively promote elasticity of skin, keep skin exquisiteness glossy.
The skin care item of anti-aging moisturizing provided by the invention are prepared by natural plant active component, safe and non-toxic secondary work
With being particularly suitable for the nursing of anaphylaxis skin, have effects that invigorate blood circulation beauty treatment, anti-aging and moisturizing, elasticity of skin can be promoted
And gloss, keep skin more fine and smooth compact.
Preferably, the Herb Gynostemmae Pentaphylli extract is the water extract of gynostemma pentaphylla.
Preferably, the American-cockroach-extract is the alcohol extract of American cockroach.
Preferably, the wet concentration is from one of deionized water, pure water and drinking water or several combinations.
Preferably, the skin care item of the moisturizing anti-aging, including the following components according to mass fraction meter:
White Flos Plumeriae Acutifoliae extract 2-4 parts, 1-3 parts of dragon's blood resin, 0.5-2 parts of Herb Gynostemmae Pentaphylli extract, American-cockroach-extract
0.5-1.5 parts, 4-6 parts of hippophae rhamnoides fruit oil, 0.5-1 parts of Rosemary Oil, 0.2-0.8 parts and water 40-56.3 parts of refined jasmine oil.
Component in skin care item is carried out preferred.
Preferably, in terms of mass fraction, further includes: 3-15 parts of emulsifier;It is furthermore preferred that the emulsifier is hard selected from glycerol
In resin acid ester, cetostearyl alcohol, dimethyl silicone polymer, polyethylene glycol -14M, docosyl alcohol polyethers -25 and stereth -21
One or more of combinations.
Emulsifier is can to improve the various surface tension constituted between phase in emulsion, is allowed to form uniform and stable point
The substance of granular media system or emulsion.Emulsifier is surface reactive material, has hydrophilic group and lipophilic group simultaneously in molecule, it assembles
On oil/water interface, interfacial tension can be reduced and reduction forms energy required for emulsion, to improve the energy of emulsion
Amount.
Preferably, in terms of mass fraction, further includes: thickener 0.1-2 parts of film forming;It is furthermore preferred that the film forming thickener
Selected from one or more of Sodium Polyacrylate, carbomer, hydroxyethyl cellulose, galactolipin araban and polyvinyl alcohol
Combination.
Preferably, in terms of mass fraction, further includes: 0.3-0.5 parts of preservative;It is furthermore preferred that the preservative is selected from benzene
One of oxyethanol, DMDM hydantoin, methyl hydroxybenzoate, Nipasol, methylisothiazolinone and parahydroxyacet-ophenone or
Several combinations.
Preferably, in terms of mass fraction, further includes: 3-5 parts of moisturizer;It is furthermore preferred that the moisturizer be selected from propylene glycol,
The combination of one or more of glycerol, allantoin, Sodium Hyaluronate, trehalose and 1,3 butanediols.
Preferably, the white Flos Plumeriae Acutifoliae extract is the ethanol extract of Cold boiled chicken egg flower;It is furthermore preferred that the Cold boiled chicken egg flower
For Cold boiled chicken egg flower of the fresh picking after drying and doing.
Preferably, the preparation method of the ethanol extract of the Cold boiled chicken egg flower, specifically includes the following steps:
The Cold boiled chicken egg flower of fresh picking is dried, is crushed, ethyl alcohol is added and impregnates smashed Cold boiled chicken egg flower, after immersion
Cold boiled chicken egg flower carries out refluxing extraction 3-4 times, and merging filtrate after ethyl alcohol is recovered under reduced pressure, obtains the ethanol extract of the Cold boiled chicken egg flower.
Preferably, the Cold boiled chicken egg flower dried is crushed to partial size less than 60 mesh by the step of crushing.
Preferably, the quality of the ethyl alcohol is 8-12 times of the Cold boiled chicken egg flower quality after drying, it is furthermore preferred that the ethyl alcohol
Mass concentration be 85%-95%.
Preferably, the temperature of the immersion is 55-65 DEG C, it is furthermore preferred that the time of the immersion is 2-3 hours.
Preferably, the temperature of the refluxing extraction is 70-75 DEG C;It is furthermore preferred that the time of the refluxing extraction is every time
1-1.5 hour.
The extracted extract of the extracting method of the white Flos Plumeriae Acutifoliae extract, concentration and purity are suitable for being conducive to skin care item
Absorption.
The preparation method of the skin care item of the moisturizing anti-aging, comprising the following steps:
By white Flos Plumeriae Acutifoliae extract, dragon's blood resin, Herb Gynostemmae Pentaphylli extract, American-cockroach-extract, 3-8 parts of hippophae rhamnoides fruit oil,
Rosemary Oil and refined jasmine oil are dissolved in water, and emulsifier, film forming thickener, preservative and moisturizer is being added, is obtaining the moisturizing
The skin care item of anti-aging.
Embodiment 1
A kind of anti-aging moisturizing revitalizer, including the component according to mass fraction shown in table 1:
The raw material of 1 embodiment 1 of table forms
The preparation method of the anti-aging moisturizing revitalizer, specifically includes the following steps:
By A phase in 75-80 DEG C of heating mixed dissolutions, B is added in appropriate amount of deionized water, at 75-80 DEG C, mixing is equal
It is even.A phase is poured into B phase emulsifying stirring, starts magnetic heating stirrer, control stirring rate is 3000r/min, is slowly added
Enter oily phase, react 15min, stop heating, be kept stirring, C is added in mixing liquid when slow cooling is to 50 DEG C, stirring is equal
It is even, homogeneous 2 minutes, continues to be cooled to 45 DEG C of dischargings, be fitted into the bottle sterilized.
Embodiment 2
A kind of antisenility skin care gel sleep mask provided by the present embodiment, including according to mass fraction shown in table 2
Component:
The raw material of 2 embodiment 2 of table forms
The preparation method of the antisenility skin care gel sleep mask, specifically includes the following steps:
A, B, C, D phase are stirred evenly respectively at room temperature respectively, B phase is slowly added in the A phase mixed, stirring is equal
It is even, then C, D are added to, it stirs evenly, is fitted into the bottle sterilized.
Embodiment 3
A kind of anti-aging essence provided by the present embodiment, including the component according to mass fraction shown in table 3:
The raw material of 3 embodiment 3 of table forms
The preparation method of the anti-aging essence, specifically includes the following steps:
A, B, C, D, E phase are stirred evenly respectively at room temperature respectively, B phase is slowly added in the A phase mixed, is stirred
Uniformly, then by C, D, E it is added to, stirs evenly, be fitted into the bottle sterilized.
Embodiment 4
A kind of antisenility skin care lotion provided by the present embodiment, including the component according to mass fraction shown in table 4:
The raw material of 4 embodiment 4 of table forms
The preparation method of the antisenility skin care lotion, specifically includes the following steps:
By D phase in 75-80 DEG C of heating mixed dissolutions, A phase is uniformly mixed after 75-80 DEG C of heating.D phase is poured into A
Magnetic heating stirrer is started in phase emulsifying stirring, and control stirring rate is 3000r/min, is stopped heating, is kept stirring,
B, C for mixing are added in mixing liquid when slow cooling is to 50 DEG C, stirs evenly, homogeneous 2 minutes, continues to be cooled to 45
DEG C, the E mixed is added to and stirs evenly discharging, is fitted into the bottle sterilized.
Test example 1 has carried out the test of the ability of total antioxidation to hundred frangipanis alcohol extracting things
Description of test: the measuring principle of total antioxidant capacity (T-AOC) assay kit: many of body polyphenoils
Matter can make Fe3+It is reduced into Fe2+, and Fe2+Stable complex compound can be formed with luxuriant and rich with fragrance quinoline substance, and by colorimetric method can to measure it anti-
The height of oxidability.
By measurement: the total antioxidant capacity of Cold boiled chicken egg flower ethanol extract is respectively 46IU/mg, 32IU/mg.
It, can be with the results showed that Cold boiled chicken egg flower ethanol extract can remove ultra-oxygen anion free radical hydroxy radical
Anti-lipid peroxidation has certain reducing power and total antioxidant capacity.I.e. it has good comprehensive oxidation resistance,
As a kind of free radical scavenger and antioxidant, before having preferable development and application in terms of the medicinal and cosmetic industry
Scape.
The test of 2 skin care item skin effect of test example
The skin effect of skin care item provided in Examples 1 to 4 is tested.Respectively security test, stabilization
Property and physical and chemical testing, moisture retention test and human test.
(1) security test
Security test is carried out to the pharmaceutical composition that the embodiment of the present invention 1 provides.
Test animal: regular grade Japan large ear rabbit 4,2.0-2.5 kilograms of weight, by unming Medical College experimental animal
The heart provides.Animal certificate number: Yunnan 2018181.Body looks into animal no abnormality seen.
Environmental condition: room temperature: 22 DEG C -23 DEG C, relative humidity: 66%-70%;
Test method:
It is tested according to " cosmetics health specification " (version in 2007) acute skin irritation, tests first 24 hours, will test
Back part of animal backbone diamond wool is cut, 3 centimetres of 3 cm x of unhairing range.0.5 gram of tested no originality is taken directly to be applied to right side skin
On skin, with the covering of clean gauze, with nonirritant immobilization with adhesive tape 2 hours.Other side is negative control.After removing tested material
1 hour, 24 hours, observation animal subject contact site dermoreaction in 72 hours 48 hours and keep a record.Test result such as table 5.
The anti-aging moisturizing revitalizer that 5 embodiment 1 of table provides is to White Rabbit acute skin irritation test result
During observation, experimental animal and tested material contact site skin have no erythema, oedema and other toxic effects.From
Table 1 is as can be seen that the anti-aging moisturizing revitalizer of the offer of embodiment 1 is strong by skin irritatin to White Rabbit acute skin irritation test
Degree is classified as nonirritant.
(2) stability and physical and chemical testing
This test has carried out stability and physical and chemical testing with embodiment 1, embodiment 1, embodiment 3, embodiment 4.
(1) cold resistance: embodiment 1, embodiment 2, embodiment 3, embodiment 4 are respectively placed in 4 bottles, cover rotation
Tightly, it is first put into 0 DEG C of refrigerator and keeps for 24 hours, then be first placed on and keep for 24 hours, taking out in -1O DEG C and -15 DEG C of refrigerators, after restoring room temperature
Observation, the product is normal, no coarse granule and dehydration.
(2) heat resistance: embodiment 1, embodiment 2, embodiment 3, embodiment 4 are respectively placed in 4 bottles, cover rotation
Tightly, it sets in insulating box and is adjusted to 40 DEG C -45 DEG C, keep for 24 hours, taking out, observing after being restored to room temperature, lotion variation without exception.
(3) pH value: respectively taking 2g for embodiment 1, embodiment 2, embodiment 3, embodiment 4, and respectively plus distilled water 20mL, stirring are equal
It is even, 45 DEG C are heated to, is then cooled to room temperature, is measured with acidometer, pH value 6.3,5.8,6.5,7.0.
(3) moisture retention is tested
This test is observed with glycerol as control sample using embodiment 2, embodiment 3.It is obtained anti-by being formulated in table 2 and 3
Aging skin-care gel sleep mask and anti-aging essence have carried out following detection.
With same specification, number weighing bottle 3 only weighs above-mentioned 3 kinds of samples respectively for observation, does not cover, and with other 3 beakers
It is tipped upside down on this 3 weighing bottles respectively, and communicates with the outside world weighing bottle contained object.From May 15 days to 2018 April in 2018
15, (25 DEG C~3O DEG C of temperature and 8O~90 RH) measured its Mass lost value in the same circumstances, and numerical value is shown in Table 6.
The dehydration of table 6 under the same conditions is compared
Test result shows that skin care item provided by embodiment 2, embodiment 3 have certain moisture retention, and moisture retention is close
Glycerol.
(4) human test
Observation on probation is carried out to 200 subjects, method is uniformly smeared per daily warm water cleaning hand and skin of face
Embodiment 4: antisenility skin care lotion 2 times/d, once in the morning and once at night, continues 28 days or more, and as a result tested crowd is without any bad anti-
It answers.
With moisturizing, tender skin, comfort, moisturizing be 4 formulations standards, with reach 4 standards be it is excellent, reaching 3 standards is
It is good, reach during 2 standards are, reaches a standard or be not improved as difference.
Observation the results are shown in Table 7.
7 human test of table observes result
Although illustrate and describing the present invention with specific embodiment, it will be appreciated that the above various embodiments is only used
To illustrate technical solution of the present invention, rather than its limitations;Those skilled in the art should understand that: without departing substantially from this hair
It in the case where bright spirit and scope, is possible to modify the technical solutions described in the foregoing embodiments, or to wherein
Some or all of technical characteristic is equivalently replaced;And these are modified or replaceed, and do not make the essence of corresponding technical solution
It departs from the scope of the technical solutions of the embodiments of the present invention;It is, therefore, intended that in the following claims including belonging to the present invention
All these substitutions and modifications in range.
Claims (10)
1. a kind of skin care item of moisturizing anti-aging, which is characterized in that including the following components according to mass fraction meter:
White Flos Plumeriae Acutifoliae extract 1-5 parts, 0.5-5 parts of dragon's blood resin, 0.1-3 parts of Herb Gynostemmae Pentaphylli extract, American-cockroach-extract
0.01-2.0 parts, 3-8 parts of hippophae rhamnoides fruit oil, 0.1-1.5 parts of Rosemary Oil, 0.05-1 parts of refined jasmine oil and water 32.27-62.47
Part;
Preferably, the Herb Gynostemmae Pentaphylli extract is the water extract of gynostemma pentaphylla;
Preferably, the American-cockroach-extract is the alcohol extract of American cockroach;
Preferably, the wet concentration is from one of deionized water, pure water and drinking water or several combinations.
2. the skin care item of moisturizing anti-aging according to claim 1, which is characterized in that including according to mass fraction meter with
Lower component:
White Flos Plumeriae Acutifoliae extract 2-4 parts, 1-3 parts of dragon's blood resin, 0.5-2 parts of Herb Gynostemmae Pentaphylli extract, American-cockroach-extract 0.5-
1.5 parts, 4-6 parts of hippophae rhamnoides fruit oil, 0.5-1 parts of Rosemary Oil, 0.2-0.8 parts and water 40-56.3 parts of refined jasmine oil.
3. the skin care item of moisturizing anti-aging according to claim 1 or 2, which is characterized in that in terms of mass fraction, also wrap
It includes: 3-15 parts of emulsifier;
Preferably, the emulsifier be selected from stearine, cetostearyl alcohol, dimethyl silicone polymer, polyethylene glycol -14M,
The combination of one or more of docosyl alcohol polyethers -25 and stereth -21.
4. the skin care item of moisturizing anti-aging according to claim 1 or 2, which is characterized in that in terms of mass fraction, also wrap
It includes: thickener 0.1-2 parts of film forming;
Preferably, the film forming thickener is selected from Sodium Polyacrylate, carbomer, hydroxyethyl cellulose, galactolipin araban
With the combination of one or more of polyvinyl alcohol.
5. the skin care item of moisturizing anti-aging according to claim 1 or 2, which is characterized in that in terms of mass fraction, also wrap
It includes: 0.3-0.5 parts of preservative;
Preferably, the preservative is selected from Phenoxyethanol, DMDM hydantoin, methyl hydroxybenzoate, Nipasol, methylisothiozoline
The combination of one or more of ketone and parahydroxyacet-ophenone.
6. the skin care item of moisturizing anti-aging according to claim 1 or 2, which is characterized in that in terms of mass fraction, also wrap
It includes: 3-5 parts of moisturizer;
Preferably, the moisturizer is in propylene glycol, glycerol, allantoin, Sodium Hyaluronate, trehalose and 1,3 butanediols
One or more of combinations.
7. the skin care item of moisturizing anti-aging according to claim 1 or 2, which is characterized in that the white Flos Plumeriae Acutifoliae extract
For the ethanol extract of Cold boiled chicken egg flower;
Preferably, the Cold boiled chicken egg flower is Cold boiled chicken egg flower of the fresh picking after drying and doing.
8. the skin care item of moisturizing anti-aging according to claim 7, which is characterized in that the ethyl alcohol of the Cold boiled chicken egg flower extracts
The preparation method of object, specifically includes the following steps:
The Cold boiled chicken egg flower of fresh picking is dried, is crushed, ethyl alcohol is added and impregnates smashed Cold boiled chicken egg flower, by the Cold boiled chicken after immersion
Egg flower carries out refluxing extraction 3-4 times, and merging filtrate after ethyl alcohol is recovered under reduced pressure, obtains the ethanol extract of the Cold boiled chicken egg flower;
Preferably, the Cold boiled chicken egg flower dried is crushed to partial size less than 60 mesh by the step of crushing;
Preferably, the quality of the ethyl alcohol is 8-12 times of the Cold boiled chicken egg flower quality after drying, it is furthermore preferred that the matter of the ethyl alcohol
Amount concentration is 85%-95%;
Preferably, the temperature of the immersion is 55-65 DEG C, it is furthermore preferred that the time of the immersion is 2-3 hours.
9. the skin care item of moisturizing anti-aging according to claim 8, which is characterized in that the temperature of the refluxing extraction is
70-75℃;
Preferably, the time of the refluxing extraction is 1-1.5 hours every time.
10. the preparation method of the skin care item of -9 described in any item moisturizing anti-agings according to claim 1, which is characterized in that packet
Include following steps:
White Flos Plumeriae Acutifoliae extract, dragon's blood resin, Herb Gynostemmae Pentaphylli extract, American-cockroach-extract, 3-8 parts of hippophae rhamnoides fruit oil, fan are changed
Essential oil and refined jasmine oil are dissolved in water, and emulsifier, film forming thickener, preservative and moisturizer is being added, it is anti-ageing to obtain the moisturizing
Old skin care item.
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