CN109171820B - Liquid sample collector - Google Patents

Liquid sample collector Download PDF

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Publication number
CN109171820B
CN109171820B CN201810913116.2A CN201810913116A CN109171820B CN 109171820 B CN109171820 B CN 109171820B CN 201810913116 A CN201810913116 A CN 201810913116A CN 109171820 B CN109171820 B CN 109171820B
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China
Prior art keywords
dyeing
layer
sample
piece
liquid
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CN201810913116.2A
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Chinese (zh)
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CN109171820A (en
Inventor
徐文淑
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Safecare Boitech Hangzhou Co ltd
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Safecare Boitech Hangzhou Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • A61B10/0051Devices for taking samples of body liquids for taking saliva or sputum samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B2010/0003Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements including means for analysis by an unskilled person
    • A61B2010/0006Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements including means for analysis by an unskilled person involving a colour change

Abstract

The invention discloses a liquid sample collector, which comprises a handle, a collecting head connected to the lower end of the handle and a dyeing piece used for displaying the sample collecting condition, wherein the handle comprises an upper holding section and a lower connecting end; the dyeing piece is of a thin structure, and the bonding layer covers the upper surface and the side surface of the dyeing piece; the lower surface of the dyeing part is provided with an isolating layer which can prevent the sample in the dyeing part from permeating into the collecting head, and the isolating layer is provided with a liquid inlet through which the sample can flow into the dyeing part. The invention has simple structure, can reflect the collection condition of the sample, and can indicate the sufficient quantity of the collected sample; the staining part can be effectively prevented from polluting the collecting head only by the reaction of the liquid inlet and the sample.

Description

Liquid sample collector
The invention application is an invention patent application with the following application numbers: 2016101984524 divisional application
Technical Field
The invention belongs to the technical field of sample collecting devices, and particularly relates to a liquid sample collector.
Background
Illicit drug abuse has become a recognized and increasingly worsening social problem in our society. Therefore, the detection of drugs has become a very important task. In order to facilitate detection, a saliva detection device is provided, and a saliva sample of a detected person is collected by a collector and then detected by a detection device. However, saliva of a drug addict is usually less, and the collector cannot reflect the collection condition of a saliva sample during collection, so that the collected sample is too few, and the detection cannot be performed. Therefore, chinese patent CN202693585U discloses a detection device, which is provided with a color developing block on a collector for displaying the collection degree of saliva, wherein when the saliva sample collected by the collection head is sufficient, the color of the indicator will change, indicating the operator. However, since the developing cartridge needs to rapidly absorb and react with the specimen, the water solubility of the developing cartridge is generally good. Therefore, when the collector collects enough quantity, the color developing block is easy to spread to the whole collecting head along with saliva, even enters the oral cavity of a human body in the collecting process, and has great potential safety hazard.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention provides the liquid sample collector which is simple, convenient and quick to collect, can indicate the collection condition and is high in safety.
In order to achieve the purpose, the invention adopts the following technical scheme: a liquid sample collector comprises a handle, a collecting head connected to the lower end of the handle and a dyeing piece used for displaying the sample collecting condition, wherein the handle comprises an upper holding section and a lower connecting section, an adhesive layer is arranged between the connecting section and the collecting head, and at least part of the connecting section is of a transparent structure; the dyeing piece is of a thin structure, and the bonding layer covers the upper surface and the side surface of the dyeing piece; the lower surface of the dyeing part is provided with an isolating layer which can prevent the sample in the dyeing part from permeating into the collecting head, and the isolating layer is provided with a liquid inlet through which the sample can flow into the dyeing part. The lower surface of the dyeing piece is provided with the isolating layer, and the upper surface and the side surface are sealed through the bonding layer, so that sealing structures are formed between the surfaces of the dyeing piece, which are contacted with the sample, and the dyeing piece is not easy to diffuse into the collecting head in the collecting process of the collecting piece, and the collecting head is not polluted; secondly, in the assembling process of the collector, the collecting head and the connecting section are connected through the bonding layer, and the dyeing piece is of a thin structure, so that the bonding layer can be used for coating the upper surface and the side surface of the dyeing piece along the belt while the collecting head is bonded, and the upper surface and the side surface of the dyeing piece are sealed and isolated; through the thin arrangement of the dyeing piece, the dual purposes of bonding and sealing of the bonding layer are realized, the operation of sealing and coating the upper surface and the side surface of the dyeing piece is omitted, the manufacturing steps are reduced, the material is saved, and the manufacturing efficiency is improved; after the upper surface and the side surface of the dyeing piece are coated, the dyed sample in the dyeing piece can be effectively prevented from permeating into the collecting head from the side wall, the collecting head is prevented from being polluted, and the safety is guaranteed; the sample is contacted with the staining part through the liquid inlet and reacts to indicate the collection condition of the sample; the area of the liquid inlet is small, so that a liquid sample can easily flow into the dyeing part, and the liquid sample is difficult to diffuse outwards through the liquid inlet, so that the accurate indication of the dyeing part can be ensured, the collection head can be prevented from being polluted, the practicability is high, and the safety is high; at least part of the connecting section is of a transparent structure, the color change reaction of the dyeing piece is observed through the transparent part, and the collector is taken out in time after sufficient collection is carried out; after the collection is finished, the time of the collector in the oral cavity is shortened to the maximum extent, and the diffusion is reduced.
Further, the dyeing piece comprises an upper dyeing layer and a lower dyeing layer.
Further, when the sample was gathered the capacity, go up the dyeing layer and show for transparent structure, the saliva sample enters into dyeing spare in, moistens dyeing spare, goes up the dyeing layer and becomes transparent after reacting with the saliva to the colour of dyeing layer is down shown, seems the colour of dyeing spare promptly by the outside and has changed, and at this moment, the operator can learn that the volume of sample collection has up to standard.
Furthermore, the liquid inlet is arranged at the central position of the dyeing part, and the liquid inlet is arranged at the central position, so that the liquid sample on the collecting head can reach the liquid inlet position only after the whole collecting head is filled with the liquid sample, and then the liquid sample enters the dyeing part to react, and the liquid sample is collected more fully; and set up the inlet in central point and put for the dyeing reaches the maximum value through the route of each side of inlet outward infiltration, but furthest prevents that dyeing from permeating to the collecting head surface when collecting the sample, prevents to get into human oral cavity, ensures the security.
Furthermore, the liquid inlet is only arranged on the lower dyeing layer, so that the operation step of arranging the liquid inlet on the upper dyeing layer is saved, and the operation is simpler and more convenient.
Furthermore, the dyeing part is arranged at the center of the bonding layer, so that the path of the dyeing part penetrating outwards from each side of the liquid inlet reaches the maximum value, the dyeing part can be prevented from penetrating into the outer surface of the collecting head to the maximum degree when a sample is collected, the dyeing part is prevented from entering the oral cavity of a human body, and the safety is guaranteed.
Furthermore, the liquid inlet is penetrated to the upper surface of the upper dyeing layer by the isolating layer, so that the whole dyeing part is penetrated through by the liquid inlet, the liquid sample can quickly permeate into the dyeing body, the absorption speed is high, and the reaction time is shortened.
Further, the bonding layer is provided with bonding glue.
In conclusion, the invention has simple structure, can reflect the collection condition of the sample and indicates the sufficient quantity of the sample collection group; only through the reaction of inlet and sample, can effectively prevent that the dyeing from polluting the condition emergence of gathering the head.
Drawings
FIG. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a partial structural schematic diagram of the present invention.
Detailed Description
In order to make the technical solutions of the present invention better understood, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention.
As shown in fig. 1-2, a liquid sample collector comprises a handle 1, a collecting head 2 and a staining member 3; the handle comprises an upper gripping section 11 and a lower connecting section 12, the connecting section 12 being configured in a circular shape, the pick head 2 being attached to the connecting section 12. The handle 1 can be made of plastic and the like, and is convenient to hold. The collecting head 2 can be made of materials with larger water absorption such as sponge and the like, and substances which promote the release of human saliva can be added into the collecting head 2 to accelerate the collection of the saliva sample in order to collect the saliva sample more quickly. The collecting head 2 and the handle 1 are connected through the bonding layer, the dyeing piece is arranged between the bonding layer 4 and the collecting head 2, the dyeing piece 3 is used for displaying the collecting condition of the sample, when the collecting amount of the saliva sample is enough, the collecting head 2 absorbs the saliva, the saliva is in contact with the dyeing piece 3, the dyeing piece is subjected to color change due to reaction, and therefore an operator is informed that the collection of the sample is completed. Since the dye member 3 is disposed between the adhesive layer 4 and the pick head 2, the discoloration of the dye member 3 needs to be observed through the connecting section of the handle. For the convenience of observation, the connecting section 12 is partially transparent, and the position of the connecting section corresponding to the dyeing part can be transparent, so that the color change of the dyeing part 3 can be observed. Of course, the whole connecting section 12, even the whole handle 1 can be directly made transparent and integrally formed, so that the manufacturing process is saved. In the present embodiment, the adhesive layer 4 is a fluid adhesive, which has a large ductility before adhesion, and can seal the peripheral wall of the dyeing material 3 well, and the adhesive is transparent after solidification, and does not affect the observation of the discoloration of the dyeing material 3. In other embodiments, other transparent adhesive materials are also possible.
Specifically, compared with the embodiment, the dyeing piece 3 is of a thin structure, specifically is of a sheet shape, and due to the small thickness, when the dyeing piece is placed between the adhesive layer 4 and the collecting head 2, the adhesive layer 4 can cover the dyeing piece, so that the upper surface and the side surface of the dyeing piece 3 are both covered, and the side wall of the dyeing piece is sealed and isolated. In order to ensure the safety of the collector, a separation layer 6 is arranged on the lower surface of the dyeing member 3, and the separation layer 6 can prevent the sample in the dyeing member 3 from permeating towards the collecting head 2. When the saliva sample is collected, the colored liquid sample in the staining part 3 cannot penetrate into the collecting head 2 from the side wall or the upper and lower surfaces of the staining part 3, and further cannot enter the oral cavity of a person, so that the safety is guaranteed. The isolation layer 6 is the coating of coating at dyeing spare lower surface, with in this embodiment, the material of isolation layer can select for use coating materials such as polyethylene, polypropylene. In other embodiments, the upper surface of the dyeing part can be coated with an isolation layer, so that double sealing isolation is realized, and the isolation effect is better.
A liquid inlet 5 is provided in the isolation layer through which the saliva sample flows only into the staining part 3, comes into contact with the staining part 3 and reacts thereby indicating the collection of the sample. Because the area of inlet is less, the liquid sample can get into in the dyeing piece easily, and the liquid in dyeing piece 3 wants through the inlet outward diffusion then is comparatively difficult to because the area is less, even outwards permeate, its area is also less, can not cause great pollution to the acquisition head. Thereby can guarantee dyeing 3 accurate instruction, can guarantee again that the pick head 2 is not polluted, the practicality is strong, and safe type is high.
Preferably, the dyeing part 3 is arranged at the central part of the adhesive layer 4, the liquid inlet 5 is also arranged at the central part of the isolation layer, and the two central parts are arranged, so that the path of the dyeing part 3 penetrating outwards through each side of the liquid inlet 5 reaches the maximum value, the color of the dyeing part 3 can be prevented from penetrating into the outer surface of the collecting head 2 to the maximum extent when a sample is collected, the color is prevented from entering the oral cavity of a human body, and the safety is guaranteed.
Specifically, the dyeing member 3 includes an upper dyeing layer 31 and a lower dyeing layer 32, the lower surface of the upper dyeing layer 31 and the upper surface of the lower dyeing layer 32 are attached together, and a gap formed between the side walls of the upper dyeing layer and the lower dyeing layer is sealed by the adhesive layer 4. In other embodiments, the staining part 3 may also be directly configured as a single-layer structure, the liquid inlet is disposed on the lower surface of the staining part, and the staining part can perform a color-changing reaction after the sample enters the staining part 3. Preferably, the liquid inlet is formed through the upper surface of the upper dyeing layer by the isolation layer, so that the liquid inlet penetrates through the upper surface of the dyeing part from the lower surface of the dyeing part, the liquid sample can quickly permeate into the dyeing part, the absorption speed is high, and the reaction time is shortened. In other embodiments, the liquid inlet may also directly pass through the isolation layer to the first dyeing layer.
In this embodiment, the upper dyeing layer 31 is set to be white, the lower dyeing layer 32 is set to be red, and the liquid inlet 5 is opened only on the lower dyeing layer 32; in other embodiments, the upper dyeing layer 31 and the lower dyeing layer 32 can both have liquid inlets 5, the liquid inlets of the upper dyeing layer 31 and the lower dyeing layer are communicated, and the upper openings of the liquid inlets 5 on the upper dyeing layer 31 are sealed by the adhesive layer 4. When a sufficient amount of sample is collected, a saliva sample enters the staining part 3 through the liquid inlet 5, so that the upper staining layer 31 and the lower staining layer 32 are both wetted, the color on the lower staining layer 32 is transferred to the upper staining layer 31, the upper staining layer 31 and the lower staining layer 32 are displayed to be the same, namely, the color of the upper staining layer 31 is also changed into red, and an operator can know that the amount of sample collection reaches the standard. In other embodiments, the color of the lower dyed layer 32 may be a vivid color such as orange, blue, etc., and the color of the upper dyed layer 31 may be a color with a higher contrast such as gray, black, etc.
In other embodiments, the indication means of the staining member 3 can be other means, for example, when a sufficient amount of the sample is collected, the saliva sample enters the staining member 3 through the liquid inlet 5, the upper staining layer 31 is not stained by the lower staining layer 32, but the saliva sample reacts with the saliva sample and then becomes a transparent structure, the color of the lower staining layer 32 below the upper staining layer is displayed, and the operator can know that the amount of the sample collected has reached the standard.
The operation process is as follows:
the collecting head is placed into the mouth of a detected person by holding the handle by hand, then the dyeing piece is observed through the connecting section of the handle, when the dyeing piece changes color, the dyeing piece shows that the collecting head collects enough, and an operator holds the handle by hand to take the collecting head out of the mouth of the detected person for next detection or analysis.
It is to be understood that the described embodiments are merely a few embodiments of the invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Claims (7)

1. A liquid sample collector comprises a handle (1), a collecting head (2) connected to the lower end of the handle (1) and a dyeing piece (3) used for displaying the sample collecting condition, wherein the handle (1) comprises an upper holding section (11) and a lower connecting section (12), an adhesive layer (4) is arranged between the connecting section (12) and the collecting head (2), and at least part of the connecting section is of a transparent structure; the method is characterized in that: the dyeing piece (3) is of a thin structure, and the bonding layer (4) covers the upper surface and the side surface of the dyeing piece (3); the lower surface of the staining part (3) is provided with an isolating layer (6) which can prevent the sample in the staining part (3) from permeating into the collecting head (2), and the isolating layer (6) is provided with a liquid inlet (5) through which the sample can flow into the staining part (3).
2. The liquid sample collector of claim 1, wherein: the dyeing member (3) comprises an upper dyeing layer (31) and a lower dyeing layer (32).
3. The liquid sample collector of claim 2, wherein: when a sufficient amount of sample is collected, the upper dye layer (31) appears as a transparent structure.
4. The liquid sample collector of claim 1, wherein: the liquid inlet (5) is arranged at the central part of the dyeing part (3).
5. The liquid sample collector of claim 2, wherein: the liquid inlet (5) penetrates through the upper surface of the upper dyeing layer (31) through the isolating layer (6).
6. The liquid sample collector of claim 1, wherein: the dyeing piece (3) is arranged at the central part of the bonding layer (4).
7. The liquid sample collector of claim 1, wherein: the bonding layer (4) is adhesive glue.
CN201810913116.2A 2016-04-01 2016-04-01 Liquid sample collector Active CN109171820B (en)

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CN201810913116.2A CN109171820B (en) 2016-04-01 2016-04-01 Liquid sample collector

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AU4789590A (en) * 1989-01-10 1990-07-19 La Mina Ltd Modular fluid multiple preparation assembly
US5211182A (en) * 1991-10-23 1993-05-18 Deutsch Marshall E Home ovulation test kit and method
CN1703615A (en) * 2002-10-09 2005-11-30 太阳星光齿磨公司 Sputum-collecting tool
CN101059404A (en) * 2007-05-11 2007-10-24 艾博生物医药(杭州)有限公司 Liquid sample collection device
CN102620953A (en) * 2012-03-14 2012-08-01 杭州安旭科技有限公司 Spittle collecting and detecting device
CN202693585U (en) * 2012-07-16 2013-01-23 杭州安旭科技有限公司 Detecting apparatus
CN202793842U (en) * 2012-07-25 2013-03-13 广州万孚生物技术股份有限公司 Saliva collecting and analyzing device
CN205697841U (en) * 2016-04-01 2016-11-23 杭州赛凯生物技术有限公司 Liquid sample harvester

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EP1463945B1 (en) * 2002-01-09 2022-06-29 Abbott Rapid Diagnostics International Unlimited Company Liquid sample assay device
JP4500191B2 (en) * 2005-03-18 2010-07-14 株式会社スズケン Biological fluid collection device
US11058404B2 (en) * 2013-05-02 2021-07-13 Echo Electricity Co., Ltd. Liquid test device
JP6071785B2 (en) * 2013-07-12 2017-02-01 株式会社堀場製作所 Concentration measuring device

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4635488A (en) * 1984-12-03 1987-01-13 Schleicher & Schuell, Inc. Nonintrusive body fluid samplers and methods of using same
AU4789590A (en) * 1989-01-10 1990-07-19 La Mina Ltd Modular fluid multiple preparation assembly
US5211182A (en) * 1991-10-23 1993-05-18 Deutsch Marshall E Home ovulation test kit and method
CN1703615A (en) * 2002-10-09 2005-11-30 太阳星光齿磨公司 Sputum-collecting tool
CN101059404A (en) * 2007-05-11 2007-10-24 艾博生物医药(杭州)有限公司 Liquid sample collection device
CN102620953A (en) * 2012-03-14 2012-08-01 杭州安旭科技有限公司 Spittle collecting and detecting device
CN202693585U (en) * 2012-07-16 2013-01-23 杭州安旭科技有限公司 Detecting apparatus
CN202793842U (en) * 2012-07-25 2013-03-13 广州万孚生物技术股份有限公司 Saliva collecting and analyzing device
CN205697841U (en) * 2016-04-01 2016-11-23 杭州赛凯生物技术有限公司 Liquid sample harvester

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CN109171820A (en) 2019-01-11
CN105726068A (en) 2016-07-06

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