CN109171010A - Liquid nicotine salt and preparation method thereof - Google Patents
Liquid nicotine salt and preparation method thereof Download PDFInfo
- Publication number
- CN109171010A CN109171010A CN201811052866.1A CN201811052866A CN109171010A CN 109171010 A CN109171010 A CN 109171010A CN 201811052866 A CN201811052866 A CN 201811052866A CN 109171010 A CN109171010 A CN 109171010A
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- Prior art keywords
- organic acid
- acid group
- nicotine salt
- nicotine
- alcohol
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Classifications
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- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
- A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
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- A24F47/008—
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- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a kind of liquid nicotine salt and preparation method, liquid nicotine salt is composed of the following components by mass percentage: basic organic acid group 27-45%；The molten organic acid group 3-10% of alcohol；Nicotine 50-65%；Basic organic acid group is made of glacial acetic acid, propionic acid, lactic acid and levulic acid, and the molten organic acid group of alcohol is made of benzoic acid, tetradecylic acid and ethyl alcohol.By the way that organic acid is added in liquid nicotine salt, the steam pH value for the tobacco tar that liquid nicotine salt is prepared reduces the present invention, less harsh to sucking, chemical reaction occurs in sucking steam course to keep higher free alkali nicotine content.This means that smoker can easily suck the tobacco tar of higher nicotine.So liquid nicotine salt ratio " free alkali " nicotine penetration power is stronger, increase the nicotine content that blood can be penetrated into same time, and will not overstimulation throat, improve the user experience of electronic cigarette.
Description
[technical field]
The present invention relates to electronic cigarettes more particularly to a kind of liquid nicotine salt and preparation method thereof.
[background technique]
Electronic cigarette is a kind of electronic product for imitating cigarette, there is appearance, smog, taste and the feeling as cigarette.
It is by the means such as atomization, after nicotine etc. is become steam, a kind of product for allowing user to suck.
Nicotine popular name nicotine is the important component of a kind of alkaloid being present in plant of Solanaceae and tobacco.Ni Gu
Fourth can be addicting or generate dependence, reuse nicotine and also increase heart speed and increase blood pressure and reduce appetite.Greatly
The nicotine of dosage can cause vomiting and nausea, and people can be dead when serious.
Usually used nicotine form is " free alkali " nicotine in electronics tobacco tar.Common " free alkali " nicotine
Tobacco tar is attempting to improve electronic cigarette equipment upper unsatisfactory to the input of blood nicotine, therefore electronic cigarette user is difficult to be taken out
The same satisfaction of cigarette.And excessively high nicotine content only resides on the overstimulation to throat, arrives in effective time
There was only very small part in up to the blood for having real demand to nicotine.Excessive thorn of the nicotine tobacco tar of high-content to throat
Swash while also reducing the user experience of electronic cigarette.
[summary of the invention]
The electronic cigarette liquid mouthfeel that the technical problem to be solved in the present invention is to provide the stimulations of a kind of pair of throat is smaller, prepares compared with
Good, liquid nicotine salt of user experience that electronic cigarette can be improved and preparation method thereof.
In order to solve the above-mentioned technical problem, the technical solution adopted by the present invention is that, a kind of liquid nicotine salt, by quality hundred
Divide than composed of the following components:
Basic organic acid group 27-45%；
The molten organic acid group 3-10% of alcohol；
Nicotine 50-65%；
Basic organic acid group is made of glacial acetic acid, propionic acid, lactic acid and levulic acid, and the molten organic acid group of alcohol is by benzoic acid, ten
Tetracid and ethyl alcohol composition.
Above-described liquid nicotine salt, basic organic acid group are composed of the following components by mass percentage:
Above-described liquid nicotine salt, the molten organic acid group of alcohol are composed of the following components by mass percentage:
Benzoic acid 20-30%；
Tetradecylic acid 4-12%；
Ethyl alcohol 60-75%.
A kind of preparation method of above-mentioned liquid nicotine salt, comprising the following steps:
1) by mass percentage, by the nicotine of the basic organic acid group of 27-45% and 50-65% at 50-60 DEG C
In the state of be mixed, reacted, obtain initial liquid nicotine salt；
2) the molten organic acid group of 3-10% alcohol by mass percentage, is added and initial liquid nicotine salt is mixed, into
Row reaction, obtains the liquid nicotine salt.
The preparation method of liquid nicotine salt described above, by mass percentage by the glacial acetic acid of 2-8%, 5-15% third
The levulic acid of acid, the lactic acid of 45-60% and 25-40% is mixed at 50-60 DEG C obtains the basic organic acid group.
The preparation method of liquid nicotine salt described above, by mass percentage by the benzoic acid of 20-30%, 4-12%
The ethyl alcohol of tetradecylic acid and 60-75% are mixed to obtain the molten organic acid group of alcohol.
Liquid nicotine salt of the invention in nicotine by being added basic organic acid group and the molten organic acid group of alcohol, liquid
The steam pH value for the tobacco tar that nicotine salt is prepared reduces, less harsh to sucking, and it is anti-that chemistry occurs in sucking steam course
It should be to keep higher free alkali nicotine content.This means that smoker can easily suck the cigarette of higher nicotine
Oil.So liquid nicotine salt ratio " free alkali " nicotine penetration power is stronger, blood can be penetrated by increasing in same time
Nicotine content, and will not overstimulation throat, improve the user experience of electronic cigarette.
[specific embodiment]
The liquid nicotine salt of the embodiment of the present invention, composed of the following components by mass percentage:
Basic organic acid group 27-45%；
The molten organic acid group 3-10% of alcohol；
Nicotine 50-65%.
Wherein,
Basic organic acid group is composed of the following components by mass percentage:
The molten organic acid group of alcohol is composed of the following components by mass percentage:
Benzoic acid 20-30%；
Tetradecylic acid 4-12%；
Ethyl alcohol 60-75%.
The preparation method of above-mentioned liquid nicotine salt, comprising the following steps:
1) by mass percentage by the second of the glacial acetic acid of 2-8%, the propionic acid of 5-15%, the lactic acid of 45-60% and 25-40%
Acyl propionic acid is mixed at 50-60 DEG C and obtains basic organic acid group.
2) ethyl alcohol of the benzoic acid of 20-30%, the tetradecylic acid of 4-12% and 60-75% is mixed by mass percentage
Obtain the molten organic acid group of alcohol.
3) by mass percentage, the shape by the nicotine of the basic organic acid group of 27-45% and 50-65% at 50-60 DEG C
It is mixed, is reacted under state, obtain initial liquid nicotine salt.
4) the molten organic acid group of 3-10% alcohol by mass percentage, is added and initial liquid nicotine salt is mixed, into
Row reaction, obtains liquid nicotine salt of the invention.
The liquid nicotine salt of the embodiment of the present invention 1, composed of the following components by mass percentage:
Basic organic acid group 35%；
The molten organic acid group 7% of alcohol；
Nicotine 58%.
Wherein,
Basic organic acid group is composed of the following components by mass percentage:
The molten organic acid group of alcohol is composed of the following components by mass percentage:
Benzoic acid 25%；
Tetradecylic acid 8%；
Ethyl alcohol (95%) 67%.
The preparation method of 1 liquid nicotine salt of embodiment, comprising the following steps:
1) levulic acid of glacial acetic acid, propionic acid, lactic acid sum is mixed at 50-60 DEG C by above-mentioned mass percent
To basic organic acid group.
2) benzoic acid, tetradecylic acid and ethyl alcohol are mixed by mass percentage to obtain the molten organic acid group of alcohol.
3) basic organic acid group and nicotine are mixed in the state of 50-60 DEG C by mass percentage, carried out anti-
It answers, obtains initial liquid nicotine salt.
4) the molten organic acid group of alcohol by mass percentage, is added and initial liquid nicotine salt is mixed, is reacted,
Obtain the liquid nicotine salt of the embodiment of the present invention 1.
2, the liquid nicotine salt of the embodiment of the present invention 1, composed of the following components by mass percentage:
Basic organic acid group 45%；
The molten organic acid group 5% of alcohol；
Nicotine 50%.
Wherein,
Basic organic acid group is composed of the following components by mass percentage:
The molten organic acid group of alcohol is composed of the following components by mass percentage:
Benzoic acid 30%；
Tetradecylic acid 10%；
Ethyl alcohol (95%) 60%.
The preparation method is the same as that of Example 1 for 2 liquid nicotine salt of embodiment.
3, the liquid nicotine salt of the embodiment of the present invention 3, composed of the following components by mass percentage:
Basic organic acid group 27%；
The molten organic acid group 8% of alcohol；
Nicotine 65%.
Wherein,
Basic organic acid group is composed of the following components by mass percentage:
The molten organic acid group of alcohol is composed of the following components by mass percentage:
Benzoic acid 20%；
Tetradecylic acid 5%；
Ethyl alcohol (95%) 75%.
The preparation method is the same as that of Example 1 for 3 liquid nicotine salt of embodiment.
4, the liquid nicotine salt of the embodiment of the present invention 4, composed of the following components by mass percentage:
Basic organic acid group 30%；
The molten organic acid group 10% of alcohol；
Nicotine 60%.
Wherein,
Basic organic acid group is composed of the following components by mass percentage:
The molten organic acid group of alcohol is composed of the following components by mass percentage:
Benzoic acid 27%；
Tetradecylic acid 10%；
Ethyl alcohol (95%) 63%.
The preparation method is the same as that of Example 1 for 4 liquid nicotine salt of embodiment.Table 1: liquid nicotine salt embodiment constituent mass
Degree table
| Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | |
| Basic organic acid group | 35 | 45 | 27 | 30 |
| The molten organic acid group of alcohol | 7 | 5 | 8 | 10 |
| Nicotine | 58 | 50 | 65 | 60 |
Table 2: basic organic acid group embodiment constituent mass degree table
| Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | |
| Glacial acetic acid | 5 | 5 | 6 | 5 |
| Propionic acid | 10 | 10 | 14 | 8 |
| Lactic acid | 52 | 58 | 42 | 52 |
| Levulic acid | 33 | 27 | 38 | 35 |
Table 3: the molten organic acid group embodiment constituent mass degree table of alcohol
| Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | |
| Benzoic acid | 25 | 30 | 20 | 27 |
| Tetradecylic acid | 8 | 10 | 5 | 10 |
| Ethyl alcohol (95%) | 67 | 60 | 75 | 63 |
For above embodiments of the present invention by the way that basic organic acid group and the molten organic acid group of alcohol are added in nicotine, liquid Buddhist nun is ancient
The steam pH value for the tobacco tar that fourth salt is prepared reduces, also less harsh to sucking, chemically reacts in sucking steam course
To keep higher free alkali nicotine content.This means that smoker can easily suck the tobacco tar of higher nicotine.
So liquid nicotine salt ratio " free alkali " nicotine penetration power is stronger, the Buddhist nun that blood can be penetrated into same time is increased
Ancient fourth is horizontal, and will not overstimulation throat, improve the user experience of electronic cigarette.
Claims (6)
1. a kind of liquid nicotine salt, which is characterized in that composed of the following components by mass percentage:
Basic organic acid group 27-45%；
The molten organic acid group 3-10% of alcohol；
Nicotine 50-65%；
Basic organic acid group is made of glacial acetic acid, propionic acid, lactic acid and levulic acid, and the molten organic acid group of alcohol is by benzoic acid, tetradecylic acid
It is formed with ethyl alcohol.
2. liquid nicotine salt according to claim 1, which is characterized in that basic organic acid group by mass percentage by with
The following group is grouped as:
3. liquid nicotine salt according to claim 1, which is characterized in that the molten organic acid group of alcohol by mass percentage by with
The following group is grouped as:
Benzoic acid 20-30%；
Tetradecylic acid 4-12%；
Ethyl alcohol 60-75%.
4. the preparation method of liquid nicotine salt described in a kind of claim 1, which comprises the following steps:
1) by mass percentage, by the nicotine of the basic organic acid group of 27-45% and 50-65% in the state of 50-60 DEG C
It is mixed, is reacted, obtain initial liquid nicotine salt；
2) the molten organic acid group of 3-10% alcohol by mass percentage, is added and initial liquid nicotine salt is mixed, carries out anti-
It answers, obtains the liquid nicotine salt.
5. the preparation method of liquid nicotine salt according to claim 4, which is characterized in that by mass percentage by 2-8%
Glacial acetic acid, the propionic acid of 5-15%, the lactic acid of 45-60% and 25-40% levulic acid be mixed and obtain at 50-60 DEG C
The basic organic acid group.
6. the preparation method of liquid nicotine salt according to claim 4, which is characterized in that by mass percentage by 20-
The ethyl alcohol of 30% benzoic acid, the tetradecylic acid of 4-12% and 60-75% is mixed to obtain the molten organic acid group of alcohol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811052866.1A CN109171010A (en) | 2018-09-10 | 2018-09-10 | Liquid nicotine salt and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811052866.1A CN109171010A (en) | 2018-09-10 | 2018-09-10 | Liquid nicotine salt and preparation method thereof |
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| CN109171010A true CN109171010A (en) | 2019-01-11 |
Family
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| CN201811052866.1A Pending CN109171010A (en) | 2018-09-10 | 2018-09-10 | Liquid nicotine salt and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111466608A (en) * | 2020-04-20 | 2020-07-31 | 铂德（深圳）科技有限公司 | Liquid sea salt nicotine and preparation method thereof |
| US11091457B2 (en) | 2019-09-03 | 2021-08-17 | Yunnan Xike Science & Technology Co., Ltd. | Synthetic nicotine composition |
| CN113912585A (en) * | 2021-11-09 | 2022-01-11 | 深圳萨特瓦生物科技有限公司 | Composite nicotine salt, preparation method and application thereof, electronic cigarette oil and electronic cigarette |
| WO2022180491A1 (en) * | 2021-02-24 | 2022-09-01 | Rai Strategic Holdings, Inc. | Aerosol precursor formulations |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2022180491A1 (en) * | 2021-02-24 | 2022-09-01 | Rai Strategic Holdings, Inc. | Aerosol precursor formulations |
| CN113912585A (en) * | 2021-11-09 | 2022-01-11 | 深圳萨特瓦生物科技有限公司 | Composite nicotine salt, preparation method and application thereof, electronic cigarette oil and electronic cigarette |
| CN113912585B (en) * | 2021-11-09 | 2023-02-24 | 深圳萨特瓦生物科技有限公司 | Composite nicotine salt, preparation method and application thereof, electronic cigarette oil and electronic cigarette |
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