CN109170688A - Day lily complex function chewable tablets and preparation method thereof - Google Patents
Day lily complex function chewable tablets and preparation method thereof Download PDFInfo
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- CN109170688A CN109170688A CN201811368927.5A CN201811368927A CN109170688A CN 109170688 A CN109170688 A CN 109170688A CN 201811368927 A CN201811368927 A CN 201811368927A CN 109170688 A CN109170688 A CN 109170688A
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- powder
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- day lily
- chewable tablets
- complex function
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- 241000756137 Hemerocallis Species 0.000 title claims abstract description 20
- 239000007910 chewable tablet Substances 0.000 title claims abstract description 16
- 238000002360 preparation method Methods 0.000 title claims description 7
- 239000000843 powder Substances 0.000 claims abstract description 58
- 235000011034 Rubus glaucus Nutrition 0.000 claims abstract description 17
- 244000235659 Rubus idaeus Species 0.000 claims abstract description 17
- 235000009122 Rubus idaeus Nutrition 0.000 claims abstract description 17
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims abstract description 16
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 14
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims abstract description 9
- 244000241838 Lycium barbarum Species 0.000 claims abstract description 9
- 235000015459 Lycium barbarum Nutrition 0.000 claims abstract description 9
- 235000015468 Lycium chinense Nutrition 0.000 claims abstract description 9
- 229920002774 Maltodextrin Polymers 0.000 claims abstract description 9
- 239000005913 Maltodextrin Substances 0.000 claims abstract description 9
- 229930195725 Mannitol Natural products 0.000 claims abstract description 9
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 9
- 229940035034 maltodextrin Drugs 0.000 claims abstract description 9
- 239000000594 mannitol Substances 0.000 claims abstract description 9
- 235000010355 mannitol Nutrition 0.000 claims abstract description 9
- 235000019359 magnesium stearate Nutrition 0.000 claims abstract description 8
- 239000000377 silicon dioxide Substances 0.000 claims abstract description 7
- 244000126002 Ziziphus vulgaris Species 0.000 claims description 4
- 235000006545 Ziziphus mauritiana Nutrition 0.000 claims description 3
- 235000008529 Ziziphus vulgaris Nutrition 0.000 claims description 3
- 238000005054 agglomeration Methods 0.000 claims description 3
- 230000002776 aggregation Effects 0.000 claims description 3
- 239000003595 mist Substances 0.000 claims description 3
- 238000007873 sieving Methods 0.000 claims description 3
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 claims description 2
- 230000007958 sleep Effects 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 5
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 6
- 206010022437 insomnia Diseases 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 4
- 208000002193 Pain Diseases 0.000 description 3
- 229940125724 sleeping drug Drugs 0.000 description 3
- 239000003826 tablet Substances 0.000 description 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 229910052710 silicon Inorganic materials 0.000 description 2
- 239000010703 silicon Substances 0.000 description 2
- 230000036578 sleeping time Effects 0.000 description 2
- 239000004408 titanium dioxide Substances 0.000 description 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 208000028399 Critical Illness Diseases 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 208000019468 Iatrogenic Disease Diseases 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- AFCARXCZXQIEQB-UHFFFAOYSA-N N-[3-oxo-3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CCNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 AFCARXCZXQIEQB-UHFFFAOYSA-N 0.000 description 1
- 208000007443 Neurasthenia Diseases 0.000 description 1
- 206010061876 Obstruction Diseases 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 229960003284 iron Drugs 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/01—Instant products; Powders; Flakes; Granules
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention is provided a kind of day lily complex function chewable tablets and is made in terms of weight fraction of following component: 40-60 parts of Radix hemerocalis plicatae powder, 5-15 parts of wolfberry fruit powder, 5-15 parts of date powder, 5-15 parts of raspberry powder, 5-15 parts of mannitol, 5-15 parts of maltodextrin, -3 parts of silica 1,0.5-2 parts of magnesium stearate.The chewable tablets has the effects that improve sleep, Anshen Bunao.
Description
Technical field
The present invention relates to food technology fields, and in particular, to a kind of day lily complex function chewable tablets and its preparation side
Method.
Background technique
Insomnia, which refers to, can not fall asleep or cannot keep sleep state, cause to have not enough sleep, and cause to fall asleep for a variety of causes tired
Difficult, Depth of sleep or frequency is too short, early awakening and sleeping time are insufficient or of poor quality etc.；Insomnia is often brought greatly to patient
Pain and psychological burden, and body can be damaged because of abuse insomnia drug, but also have many methods that can alleviate and treat mistake
It sleeps.
Insomnia is one of common clinical disease, though being not belonging to critical illness, interferes people's normal life, work, study
And health, and can aggravate or induce the illnesss such as palpitaition, thoracic obstruction, dizziness, headache, apoplexy.Obstinate insomnia, brings to patient
Long-term pain, or even the dependence to sleeping drug is formed, and iatrogenic disease can be caused by taking sleeping drug for a long time.
The nutritive value of day lily is very high, wherein the protein and mineral phosphor that contain, iron, vitamin A, vitamin C energy
It is enough fully to supplement body nutrition, recorded according to Chinese medicine books, day lily have detumescence, diuresis, it is antipyretic, relieve pain, enrich blood, eliminating the pregnancy period
The effect of malaise symptoms.On the basis of using day lily as major ingredient, it is aided with the synthesis of the material such as fructus lycii, jujube, fructus lycii, raspberry, by super
At day lily fruit-vegetable nutrition powder, having by tablet forming technique exploitation improves the specific functions such as sleep, Anshen Bunao for Crushing of Ultrafine research and development
Series chewing flake products.
Summary of the invention
It is an object of the invention to overcome the deficiencies of the prior art and provide a kind of day lily complex function chewable tablets and its systems
Preparation Method, the chewable tablets have the effects that improve sleep, Anshen Bunao.
Day lily complex function chewable tablets of the present invention is made of following component based on parts by weight:
40-60 parts of Radix hemerocalis plicatae powder, 5-15 parts of wolfberry fruit powder, 5-15 parts of date powder, 5-15 parts of raspberry powder, 5-15 parts of mannitol, malt paste
It is 5-15 parts smart, -3 parts of silica 1,0.5-2 parts of magnesium stearate.
Wherein the Radix hemerocalis plicatae powder is 50-60 parts preferred.
Wherein the raspberry powder is 10-15 parts preferred.
The maltodextrin is 7-12 parts preferred, and dosage is very few, is not easy to be pressed into piece.
Day lily complex function chewable tablets of the present invention the preparation method is as follows:
It is finely divided after the coarse crushing of day lily elder generation, 60-100 mesh is crossed into uniform fine powder；After the broken agglomeration of fructus lycii micro mist coarse crushing and
Ultra-micro Chinese date powder is directly added into, and sieving is added in composite raw powder after raspberry powder is finely divided, is proportionally added into other compositions, is expected with reason
After machine mixes, tabletting.
Beneficial effects of the present invention: have the effects that improve sleep, Anshen Bunao, the shelf-life 12 months.
The eating method of day lily complex function chewable tablets of the present invention: direct-edible, 3 times a day, 1 tablet once, and every
20 grams.
Specific embodiment
Below with reference to embodiment, invention is further described in detail, but is not limitation of the present invention.
Embodiment 1
50 grams of Radix hemerocalis plicatae powder, 10 grams of wolfberry fruit powder, 10 grams of date powder, 10 grams of raspberry powder, 10 grams of mannitol, 8 grams of maltodextrin, titanium dioxide
2 grams of silicon, 1 gram of magnesium stearate.
Embodiment 2
50 grams of Radix hemerocalis plicatae powder, 12 grams of wolfberry fruit powder, 8 grams of date powder, 12 grams of raspberry powder, 8 parts of mannitol, 7 grams of maltodextrin, silica
1.5 grams, 0.9 gram of magnesium stearate.
Embodiment 3
50 grams of Radix hemerocalis plicatae powder, 8 grams of wolfberry fruit powder, 12 grams of date powder, 8 grams of raspberry powder, 12 grams of mannitol, 7.5 grams of maltodextrin, titanium dioxide
1 gram of silicon, 0.8 gram of magnesium stearate.
Embodiment 4
50 grams of Radix hemerocalis plicatae powder, 9 grams of wolfberry fruit powder, 13 grams of date powder, 9 grams of raspberry powder, 11 grams of mannitol, 9 grams of maltodextrin, silica
1 gram, 0.9 gram of magnesium stearate.
Comparative example 1
9 grams of wolfberry fruit powder, 13 grams of date powder, 59 grams of raspberry powder, 11 grams of mannitol, 9 grams of maltodextrin, silica 1 gram, magnesium stearate
0.9 gram.
Comparative example 2
59 grams of Radix hemerocalis plicatae powder, 9 grams of wolfberry fruit powder, 13 grams of date powder, 11 grams of mannitol, 9 grams of maltodextrin, silica 1 gram, stearic acid
0.9 gram of magnesium.
Wherein comparative example 1 removes Radix hemerocalis plicatae powder, and raspberry powder increases to 59 grams, other same as Example 4；Comparative example 2
Raspberry powder is removed, Radix hemerocalis plicatae powder increases to 59 grams, other same as Example 4.
Above embodiments, comparative example the preparation method is as follows:
It is finely divided after the coarse crushing of day lily elder generation, 60 meshes are crossed into uniform fine powder；It is after the broken agglomeration of fructus lycii micro mist coarse crushing and existing
Ultra-micro Chinese date powder be directly added into, raspberry powder it is finely divided after sieving be added composite raw powder in；It is proportionally added into ingredient, uses arranging machine
After mixing, tabletting.
Neurasthenia degree comparable 60 easy insomniacs (sleeping time is between 4-5 hours every night) are taken into reality respectively
The chewable tablets of a 1-4 and comparative example 1-2 are applied, 3 times a day, 1 tablet once, and every 20 grams；
Period does not take any sleeping drug, and after 1 month, effect is shown in Table 1.
Table 1
。
As seen from Table 1, there is synergistic effect in terms of sleeping in formula system of the invention, Radix hemerocalis plicatae powder and raspberry powder.
Claims (5)
1. a kind of day lily complex function chewable tablets, it is characterised in that based on parts by weight, be made of following component:
40-60 parts of Radix hemerocalis plicatae powder, 5-15 parts of wolfberry fruit powder, 5-15 parts of date powder, 5-15 parts of raspberry powder, 5-15 parts of mannitol, malt paste
It is 5-15 parts smart, -3 parts of silica 1,0.5-2 parts of magnesium stearate.
2. day lily complex function chewable tablets according to claim 1, it is characterised in that the Radix hemerocalis plicatae powder is 50-60
Part.
3. day lily complex function chewable tablets according to claim 1, it is characterised in that the raspberry powder is 10-15
Part.
4. day lily complex function chewable tablets according to claim 1, it is characterised in that the maltodextrin is 7-12
Part.
5. the preparation method of day lily complex function chewable tablets according to claim 1, it is characterised in that successively include as follows
Step: it is finely divided after the coarse crushing of day lily elder generation, 60-100 mesh is crossed into uniform fine powder；After the broken agglomeration of fructus lycii micro mist coarse crushing and
Ultra-micro Chinese date powder is directly added into Radix hemerocalis plicatae powder, raspberry powder it is finely divided after sieving be added Radix hemerocalis plicatae powder in, be proportionally added into other at
Point, after mixing, tabletting.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811368927.5A CN109170688A (en) | 2018-11-16 | 2018-11-16 | Day lily complex function chewable tablets and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811368927.5A CN109170688A (en) | 2018-11-16 | 2018-11-16 | Day lily complex function chewable tablets and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109170688A true CN109170688A (en) | 2019-01-11 |
Family
ID=64939546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811368927.5A Pending CN109170688A (en) | 2018-11-16 | 2018-11-16 | Day lily complex function chewable tablets and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109170688A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116058503A (en) * | 2022-12-31 | 2023-05-05 | 贵州斛妍堂生物科技有限公司 | Polygonatum sibiricum chewable tablet capable of improving sleep and relieving fatigue and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110076349A1 (en) * | 2008-05-30 | 2011-03-31 | Koichi Yoshihara | Composition containing hot-water extract of plant of the genus hemerocallis and having antidepressant-like effects or fatigue-relieving effects based on sleep improvement |
| CN102228250A (en) * | 2011-07-08 | 2011-11-02 | 北京工商大学 | Functional food for sleep improvement and preparation method thereof |
| CN107198011A (en) * | 2017-06-20 | 2017-09-26 | 哈尔滨工业大学 | A kind of special antidepression raspberry lozenge dry process formula of astronaut |
-
2018
- 2018-11-16 CN CN201811368927.5A patent/CN109170688A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110076349A1 (en) * | 2008-05-30 | 2011-03-31 | Koichi Yoshihara | Composition containing hot-water extract of plant of the genus hemerocallis and having antidepressant-like effects or fatigue-relieving effects based on sleep improvement |
| CN102228250A (en) * | 2011-07-08 | 2011-11-02 | 北京工商大学 | Functional food for sleep improvement and preparation method thereof |
| CN107198011A (en) * | 2017-06-20 | 2017-09-26 | 哈尔滨工业大学 | A kind of special antidepression raspberry lozenge dry process formula of astronaut |
Non-Patent Citations (2)
| Title |
|---|
| 李欧等: "萱草花药理作用研究进展", 《上海中医药杂志》 * |
| 王晴: "《心理疾病与防治》", 31 July 2006, 对外经济贸易大学出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116058503A (en) * | 2022-12-31 | 2023-05-05 | 贵州斛妍堂生物科技有限公司 | Polygonatum sibiricum chewable tablet capable of improving sleep and relieving fatigue and preparation method thereof |
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Application publication date: 20190111 |
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