CN109125413A - A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect - Google Patents
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect Download PDFInfo
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- 238000002360 preparation method Methods 0.000 title claims abstract description 61
- 239000000203 mixture Substances 0.000 title claims abstract description 35
- 230000000694 effects Effects 0.000 title claims abstract description 31
- 210000003734 kidney Anatomy 0.000 title claims abstract description 31
- 238000005728 strengthening Methods 0.000 title claims abstract description 27
- 210000001550 testis Anatomy 0.000 claims abstract description 112
- 241000282994 Cervidae Species 0.000 claims abstract description 22
- 241000336315 Cistanche salsa Species 0.000 claims abstract description 22
- 240000000759 Lepidium meyenii Species 0.000 claims abstract description 22
- 235000000421 Lepidium meyenii Nutrition 0.000 claims abstract description 22
- 241001508687 Mustela erminea Species 0.000 claims abstract description 22
- 241000283898 Ovis Species 0.000 claims abstract description 22
- 244000309464 bull Species 0.000 claims abstract description 22
- 235000012902 lepidium meyenii Nutrition 0.000 claims abstract description 22
- 230000002381 testicular Effects 0.000 claims abstract description 21
- 241000756943 Codonopsis Species 0.000 claims abstract description 20
- 239000000126 substance Substances 0.000 claims abstract description 18
- 239000003814 drug Substances 0.000 claims abstract description 14
- 239000002775 capsule Substances 0.000 claims abstract description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 12
- 235000019441 ethanol Nutrition 0.000 claims description 6
- 239000000843 powder Substances 0.000 claims description 4
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- 239000002994 raw material Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 abstract description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 7
- 239000008280 blood Substances 0.000 abstract description 5
- 210000004369 blood Anatomy 0.000 abstract description 5
- 210000003414 extremity Anatomy 0.000 abstract description 5
- 201000001881 impotence Diseases 0.000 abstract description 5
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- 206010003549 asthenia Diseases 0.000 abstract description 4
- 210000004185 liver Anatomy 0.000 abstract description 4
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- 102000009151 Luteinizing Hormone Human genes 0.000 description 2
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- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 2
- 235000003140 Panax quinquefolius Nutrition 0.000 description 2
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 description 2
- 230000002124 endocrine Effects 0.000 description 2
- 235000008434 ginseng Nutrition 0.000 description 2
- 210000004907 gland Anatomy 0.000 description 2
- 235000012907 honey Nutrition 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
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- 230000000638 stimulation Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 238000001949 anaesthesia Methods 0.000 description 1
- 210000003056 antler Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- FCPVYOBCFFNJFS-LQDWTQKMSA-M benzylpenicillin sodium Chemical compound [Na+].N([C@H]1[C@H]2SC([C@@H](N2C1=O)C([O-])=O)(C)C)C(=O)CC1=CC=CC=C1 FCPVYOBCFFNJFS-LQDWTQKMSA-M 0.000 description 1
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- 238000010255 intramuscular injection Methods 0.000 description 1
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- 239000002504 physiological saline solution Substances 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/64—Orobanchaceae (Broom-rape family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, bulk pharmaceutical chemicals are formed according to parts by weight are as follows: testis of donky 70-150, bull testis 70-180, dog testis 70-150, ermine testis 40-100, Testis Caprae seu Ovis 60-130, deer testicular 70-150, Maca 70-150, male tussah chrysalis 50-140, codonopsis lanceolata 50-150 and broomrape 10-80, capsule can be made in it, tablet, the peroral dosage forms such as pill.By all medicine compatibilities, reach enriching essence and nourishing marrow, nourishing liver and kidney, establishing-Yang promoting blood circulation enhances the function of immunity of organism, for treating impotence, premature ejaculation, blood and essence asthenia, soreness and weakness of waist and knees, the diseases such as limbs fatigue are significant in efficacy, and have no toxic side effect.
Description
Technical field
The Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect that the present invention relates to a kind of belongs to Chinese medicine neck
Domain.
Background technique
Kidney-nourishing yang-strengthening medicine refers to for promoting male's sexual desire and promoting the drug of sexual function.Common establishing-Yang object in Chinese medicine
There are pilose antler, dog testes and penis etc..Chinese medicine thinks, thanks to disease is mostly to roll up disease, can't to use the medicine of benefit greatly to nourish with anxious for success, and
It should slowly improve.Having inside Western medicine medea much will lead to blood pressure decline, will form faintness and shock if hypopiesia
Symptom, long-term takes, and can also generate dependence, once stopping using, sexual function can be more and more disappointing.Some patients can also go out
The eyesight of existing transience is in a trance.Chinese medicine often has the shortcomings that overcome the characteristic of Western medicine, plays the spy for the treatment of both manifestation and root cause of disease or Small side effects
Point.
Summary of the invention
The Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect that the present invention provides a kind of.
To achieve the above object, a kind of technical solution provided by the invention are as follows: Chinese traditional medicine composition with tonifying kidney and strengthening yang effect
Object preparation and preparation method thereof, which is characterized in that bulk pharmaceutical chemicals are formed according to parts by weight are as follows: testis of donky 70-150, bull testis 70-
180, dog testis 70-150, ermine testis 40-100, Testis Caprae seu Ovis 60-130, deer testicular 70-150, Maca 70-150, male tussah chrysalis
50-140, codonopsis lanceolata 50-150 and broomrape 10-80.
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, preferred weight are as follows:
Testis of donky 130, bull testis 150, dog testis 120, ermine testis 90, Testis Caprae seu Ovis 110, deer testicular 120, Maca 120, male tussah chrysalis
100, codonopsis lanceolata 110 and broomrape 50.
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, comprising the following steps:
(1) testis of donky, bull testis, dog testis, ermine testis, Testis Caprae seu Ovis, deer testicular, Maca, codonopsis lanceolata, broomrape crushing are weighed
Afterwards, 20 meshes, sterilizing are crossed；
(2) male tussah chrysalis is weighed, after adding 2 times of amount ethyl alcohol to impregnate, is ground into homogenate shape with refiner, is centrifuged, takes supernatant, 70 DEG C
Ethyl alcohol is recovered under reduced pressure, and is concentrated into the medicinal extract that relative density is 1.20~1.22,70 DEG C are dried under reduced pressure, and crush；
(3) powder of (1) and (2) is merged be added customary adjuvant to get.
The feature of invention formulation includes capsule, tablet, pill.
Beneficial effects of the present invention: the present invention provides one kind to have liver and kidney benefiting, and replenishing vital essence and blood nourishes kidney yang, raising property function
Can Chinese medicinal composition preparation and preparation method thereof, using testis of donky, bull testis, dog testis, ermine testis, Testis Caprae seu Ovis, deer testicular,
Maca, male tussah chrysalis, codonopsis lanceolata and broomrape reach the curative effect of tonifying kidney and strengthening yang by all medicine compatibilities, enhance immunity of organism function
Energy.For treating impotence, premature ejaculation, blood and essence asthenia, soreness and weakness of waist and knees, the diseases such as limbs fatigue are significant in efficacy and have no toxic side effect.
Specific embodiment
Embodiment 1
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, bulk pharmaceutical chemicals are formed according to parts by weight are as follows:
Testis of donky 130, bull testis 150, dog testis 120, ermine testis 90, Testis Caprae seu Ovis 110, deer testicular 120, Maca 120, male tussah chrysalis
100, codonopsis lanceolata 110 and broomrape 50.
(1) testis of donky, bull testis, dog testis, ermine testis, Testis Caprae seu Ovis, deer testicular, Maca, codonopsis lanceolata, broomrape are weighed
After crushing, 20 meshes, sterilizing are crossed；
(2) male tussah chrysalis is weighed, after adding 2 times of amount ethyl alcohol to impregnate, is ground into homogenate shape with refiner, is centrifuged, takes supernatant, 70 DEG C
Ethyl alcohol is recovered under reduced pressure, and is concentrated into the medicinal extract that relative density is 1.20~1.22,70 DEG C are dried under reduced pressure, and crush；
(3) powder of (1) and (2) is merged be added customary adjuvant to get.
Embodiment 2
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, bulk pharmaceutical chemicals are formed according to parts by weight are as follows:
Testis of donky 110, bull testis 140, dog testis 120, ermine testis 100, Testis Caprae seu Ovis 120, deer testicular 110, Maca 130, male tussah chrysalis
110, codonopsis lanceolata 120 and broomrape 40.
Operating procedure is the same as embodiment 1.
Embodiment 3
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, bulk pharmaceutical chemicals are formed according to parts by weight are as follows:
Testis of donky 90, bull testis 120, dog testis 140, ermine testis 70, Testis Caprae seu Ovis 140, deer testicular 150, Maca 90, male tussah chrysalis 130,
Codonopsis lanceolata 80 and broomrape 70.
Operating procedure is the same as embodiment 1.
Embodiment 4
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, bulk pharmaceutical chemicals are formed according to parts by weight are as follows:
Testis of donky 70, bull testis 100, dog testis 130, ermine testis 130, Testis Caprae seu Ovis 130, deer testicular 90, Maca 140, male tussah chrysalis 80,
Codonopsis lanceolata 150 and broomrape 60.
Operating procedure is the same as embodiment 1.
Comparative example 1
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, bulk pharmaceutical chemicals are formed according to parts by weight are as follows:
Bull testis 150, dog testis 120, ermine testis 90, Testis Caprae seu Ovis 110, deer testicular 120, Maca 120, male tussah chrysalis 100, codonopsis lanceolata
110 and broomrape 50.
Operating procedure is the same as embodiment 1.
Comparative example 2
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, bulk pharmaceutical chemicals are formed according to parts by weight are as follows:
Testis of donky 130, dog testis 120, ermine testis 90, Testis Caprae seu Ovis 110, deer testicular 120, Maca 120, male tussah chrysalis 100, codonopsis lanceolata
110 and broomrape 50.
Operating procedure is the same as embodiment 1.
Comparative example 3
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, bulk pharmaceutical chemicals are formed according to parts by weight are as follows:
Testis of donky 130, bull testis 150, ermine testis 90, Testis Caprae seu Ovis 110, deer testicular 120, Maca 120, male tussah chrysalis 100, codonopsis lanceolata
110 and broomrape 50.
Operating procedure is the same as embodiment 1.
Comparative example 4
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, bulk pharmaceutical chemicals are formed according to parts by weight are as follows:
Testis of donky 130, bull testis 150, dog testis 120, Testis Caprae seu Ovis 110, deer testicular 120, Maca 120, male tussah chrysalis 100, wheel blade party
Ginseng 110 and broomrape 50.
Operating procedure is the same as embodiment 1.
Comparative example 5
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, bulk pharmaceutical chemicals are formed according to parts by weight are as follows:
Testis of donky 130, bull testis 150, dog testis 120, ermine testis 90, deer testicular 120, Maca 120, male tussah chrysalis 100, codonopsis lanceolata
110 and broomrape 50.
Operating procedure is the same as embodiment 1.
Comparative example 6
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, bulk pharmaceutical chemicals are formed according to parts by weight are as follows:
Testis of donky 130, bull testis 150, dog testis 120, ermine testis 90, Testis Caprae seu Ovis 110, Maca 120, male tussah chrysalis 100, codonopsis lanceolata
110 and broomrape 50.
Operating procedure is the same as embodiment 1.
Comparative example 7
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, bulk pharmaceutical chemicals are formed according to parts by weight are as follows:
Testis of donky 130, bull testis 150, dog testis 120, ermine testis 90, Testis Caprae seu Ovis 110, deer testicular 120, male tussah chrysalis 100, wheel blade party
Ginseng 110 and broomrape 50.
Operating procedure is the same as embodiment 1.
Comparative example 8
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, bulk pharmaceutical chemicals are formed according to parts by weight are as follows:
Testis of donky 130, bull testis 150, dog testis 120, ermine testis 90, Testis Caprae seu Ovis 110, deer testicular 120, Maca 120, codonopsis lanceolata
110 and broomrape 50.
Operating procedure is the same as embodiment 1.
Comparative example 9
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, bulk pharmaceutical chemicals are formed according to parts by weight are as follows:
Testis of donky 130, bull testis 150, dog testis 120, ermine testis 90, Testis Caprae seu Ovis 110, deer testicular 120, Maca 120, male tussah chrysalis
100 and codonopsis lanceolata 110.
Operating procedure is the same as embodiment 1.
Comparative example 10
A kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, bulk pharmaceutical chemicals are formed according to parts by weight are as follows:
Testis of donky 130, bull testis 150, dog testis 120, ermine testis 90, Testis Caprae seu Ovis 110, deer testicular 120, Maca 120, male tussah chrysalis
100 and broomrape 50.
Operating procedure is the same as embodiment 1.
Comparative example 11
Street drug YISHEN XINGYANG JIAONANG.
The animal experiment method and conclusion of Chinese medicinal composition preparation of the invention:
The male rat for taking 130-150 g, in addition to blank control group, rat carries out castration after giving chloraldurate local anaesthesia
Art, postoperative 40,000 U/kg of intramuscular injection Benzylpenicillin sodium salt, continuous 3 d.After castration is performed the operation 2 weeks, castrated rats are grouped at random: model group is controlled
Treatment group (drug that each group gives same dose), Normal group and the isometric physiological saline of model group stomach-filling, are administered daily 1
Secondary, successive administration 28d, 1h, is placed in a rat penis position (electrode for the stimulating electrode of electronic stimulation instrument after the last administration
It is put in orificium urethrae externum, another electrode is placed in skin of penis, and current strength is 4 mA), record is since stimulation to when telotism
Between latent time as telotism, be shown in Table 1, the results showed that, compared with model group, treatment group can be obviously shortened telotism
Latent time can reach normal rat level substantially.Hematometry serum testosterone (T), flitropin are taken when off-test
(FSH), interstitialcellstimulating hormone (ICSH) (LH) concentration, is shown in Table 2, the results showed that, compared with model group, treatment group can improve castrated rats
Gland endocrine hormone content can reach normal rat level substantially.
Table 1: the influence of rat telotism latent time
| Group | Telotism latent time (s) |
| Embodiment 1 | 25.1±4.4** |
| Embodiment 2 | 26.7±4.8** |
| Embodiment 3 | 28.7±4.2** |
| Embodiment 4 | 27.6±5.6** |
| Comparative example 1 | 31.8±4.7** |
| Comparative example 2 | 32.4±4.8** |
| Comparative example 3 | 34.7±5.3** |
| Comparative example 4 | 32.5±5.1** |
| Comparative example 5 | 36.5±6.3* |
| Comparative example 6 | 38.4±5.5* |
| Comparative example 7 | 35.3±4.8** |
| Comparative example 8 | 33.6±5.1** |
| Comparative example 9 | 32.4±4.4** |
| Comparative example 10 | 38.6±5.3* |
| Comparative example 11 | 28.9±5.7** |
| Normal group | 23.3±4.5** |
| Model group | 45.2±6.3 |
Compared with model group: * * P ﹤ 0.01；* P ﹤ 0.05.
Table 2: the influence of rat sexual gland endocrine hormone content
| Group | T(ng/L) | FSH(IU/L) | LH(IU/L) |
| Embodiment 1 | 63.26±21.45** | 1.78±0.42** | 1.05±0.25** |
| Embodiment 2 | 59.62±23.72** | 1.89±0.45** | 1.17±0.24** |
| Embodiment 3 | 57.66±24.58** | 1.85±0.36** | 1.15±0.28** |
| Embodiment 4 | 56.91±23.17** | 1.92±0.39** | 1.12±0.21** |
| Comparative example 1 | 47.16±21.6** | 2.11±0.32** | 1.27±0.31** |
| Comparative example 2 | 44.67±21.13* | 2.23±0.43* | 1.26±0.28** |
| Comparative example 3 | 45.91±23.86* | 2.21±0.29** | 1.30±0.23** |
| Comparative example 4 | 43.78±20.48* | 2.14±0.44** | 1.24±0.27** |
| Comparative example 5 | 45.87±22.85* | 2.18±0.33** | 1.28±0.26** |
| Comparative example 6 | 46.53±21.32* | 2.17±0.31** | 1.28±0.24** |
| Comparative example 7 | 46.98±21.97* | 2.26±0.36* | 1.31±0.30** |
| Comparative example 8 | 47.16±22.77** | 2.13±0.37** | 1.29±0.29** |
| Comparative example 9 | 48.15±20.89** | 2.24±0.39** | 1.24±0.22** |
| Comparative example 10 | 42.98±21.35* | 2.27±0.35* | 1.32±0.29** |
| Comparative example 11 | 62.79±22.69** | 1.82±0.44** | 1.07±0.24** |
| Normal group | 71.24±26.36** | 1.67±0.35** | 0.99±0.21** |
| Pathological model group | 27.51±13.74 | 2.73±0.43 | 1.67±0.27 |
Compared with model group: * * P ﹤ 0.01；* P ﹤ 0.05.
The clinical test methods and typical case of Chinese medicinal composition preparation of the invention:
1, selection example 1 is prepared into capsule；
2, function: enriching essence and nourishing marrow, nourishing liver and kidney, establishing-Yang promoting blood circulation；
3, the major functions: impotence, premature ejaculation, blood and essence asthenia, soreness and weakness of waist and knees, the diseases such as limbs fatigue；
4, treatment method: it is oral, three times per day, and 6 tablets each time, a month as a treatment course.
Case 1:
Tang, 28 years old, male, patient had masturbation history, and nearly half a year finds that penis impotence is soft and do not lift that soreness and weakness of waist and knees, spiritlessness and weakness, four ends are not
Temperature, tongue nature is light red, and tongue fur is thin and white, deep-slow pulse.After taking one course for the treatment of of capsule of the invention, symptom disappears substantially, continues to take
After a course for the treatment of, sexual life is normal.
Case 2:
Liu, male, 35 years old, 5 years s.m.ps after marriage, tongue nature was fat tender, Weak pulse symptoms include premature ejaculation, soreness of waist pain, limbs fatigue.Essence
Fluid inspection is shown: sperm survival rate is only 15%-25%.After taking two courses for the treatment of of capsule of the invention, symptom disappears substantially, essence
Sub- survival rate reaches 60%, continues after taking two courses for the treatment of, and sperm survival rate reaches 80%, and above-mentioned symptom all disappears, next year its
Lover is able to gestation, one female of natural labor.
By above-mentioned verifying, Chinese medicinal composition preparation of the invention is combined by using specific bulk pharmaceutical chemicals and dosage, right
The treatment of impotence, premature ejaculation, blood and essence asthenia, soreness and weakness of waist and knees, the diseases such as limbs fatigue achieves unexpected effect, shows the present invention
Chinese medicinal composition preparation have obvious enriching essence and nourishing marrow, it is nourishing liver and kidney, establishing-Yang promoting blood circulation effect.
The preparation of 5 capsule of embodiment:
Step (1)-(3) are the same as embodiment 1；
Mixture obtained by (3) is distributed into capsule after mixing by step (4), be made 3000 to get.
The preparation of 6 tablet of embodiment:
Step (1)-(3) are the same as embodiment 1；
Step (4) is by mixture obtained by (3), tabletting after mixing, be made 2000 to get.
The preparation of 7 pill of embodiment:
Step (1)-(3) are the same as embodiment 1；
Step (4) is by mixture obtained by (3), and after mixing, every 100g powder refined honey 50g adds appropriate water pill, dry, and water is made
Honeyed bolus；Or add refined honey 100g that big honeyed bolus is made.
Above content is the description of the invention, is not limitation of the invention, after any pair of simple transformation of the present invention
Scheme all belongs to the scope of protection of the present invention.
Claims (4)
1. a kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect, which is characterized in that by following weight
Part bulk pharmaceutical chemicals are made: testis of donky 70-150, bull testis 70-180, dog testis 70-150, ermine testis 40-100, Testis Caprae seu Ovis 60-
130, deer testicular 70-150, Maca 70-150, male tussah chrysalis 50-140, codonopsis lanceolata 50-150 and broomrape 10-80.
2. a kind of Chinese medicinal composition preparation and preparation method thereof with tonifying kidney and strengthening yang effect according to claim 1,
It is characterized in that, each raw material medicines in portions by weight are as follows: testis of donky 130, bull testis 150, dog testis 120, ermine testis 90, Testis Caprae seu Ovis 110, deer
Testis 120, Maca 120, male tussah chrysalis 100, codonopsis lanceolata 110 and broomrape 50.
3. a kind of Chinese medicinal composition preparation and preparation method thereof described in claim 1 with tonifying kidney and strengthening yang effect, feature
It is, comprising the following steps:
(1) testis of donky, bull testis, dog testis, ermine testis, Testis Caprae seu Ovis, deer testicular, Maca, codonopsis lanceolata, broomrape crushing are weighed
Afterwards, 20 meshes, sterilizing are crossed；
(2) male tussah chrysalis is weighed, after adding 2 times of amount ethyl alcohol to impregnate, is ground into homogenate shape with refiner, is centrifuged, takes supernatant, 70 DEG C
Ethyl alcohol is recovered under reduced pressure, and is concentrated into the medicinal extract that relative density is 1.20~1.22,70 DEG C are dried under reduced pressure, and crush；
(3) powder of (1) and (2) is merged be added customary adjuvant to get.
4. a kind of Chinese medicinal composition preparation of any of claims 1 or 2, preparation described in feature includes capsule, tablet, ball
Agent.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113425744A (en) * | 2021-07-29 | 2021-09-24 | 青海特健生物科技有限公司 | Preparation method of sheep testis decoction pieces |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1124630A (en) * | 1994-12-14 | 1996-06-19 | 廖玉生 | Tonic tincture of multi-animal testises and producing process thereof |
| CN1732986A (en) * | 2005-08-08 | 2006-02-15 | 曹永胜 | Concentrated tablet of animal testis and process for preparing the same |
| CN103638047A (en) * | 2013-11-25 | 2014-03-19 | 江西济民可信药业有限公司 | Preparation method of testicle tablet |
-
2018
- 2018-11-06 CN CN201811314828.9A patent/CN109125413A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1124630A (en) * | 1994-12-14 | 1996-06-19 | 廖玉生 | Tonic tincture of multi-animal testises and producing process thereof |
| CN1732986A (en) * | 2005-08-08 | 2006-02-15 | 曹永胜 | Concentrated tablet of animal testis and process for preparing the same |
| CN103638047A (en) * | 2013-11-25 | 2014-03-19 | 江西济民可信药业有限公司 | Preparation method of testicle tablet |
Non-Patent Citations (4)
| Title |
|---|
| 宗绍峰: "《一针见穴：手指上的医院》", 31 December 2017, 云南科技出版社 * |
| 江培良: "《实用本草药性歌括》", 31 January 2007, 中国医药科技出版社 * |
| 王志新等: "《长白山珍贵山野菜栽培及加工技术》", 31 December 2006, 吉林科学技术出版社 * |
| 陈寿宏: "《中华食材 下》", 30 April 2016, 合肥工业大学出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113425744A (en) * | 2021-07-29 | 2021-09-24 | 青海特健生物科技有限公司 | Preparation method of sheep testis decoction pieces |
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