CN109091570B

CN109091570B - Traditional Chinese medicine for treating scleroderma

Info

Publication number: CN109091570B
Application number: CN201811338608.XA
Authority: CN
Inventors: 华金双; 华银双; 张君; 邵素菊; 王培育
Original assignee: Henan University of Traditional Chinese Medicine HUTCM
Current assignee: Henan University of Traditional Chinese Medicine HUTCM
Priority date: 2018-11-12
Filing date: 2018-11-12
Publication date: 2021-07-02
Anticipated expiration: 2038-11-12
Also published as: CN109091570A

Abstract

The invention relates to a traditional Chinese medicine for treating scleroderma, which can effectively solve the problem of medicine application of the scleroderma and adopts the technical scheme that the traditional Chinese medicine is prepared from the following raw medicines in parts by weight: 10-15 parts of caulis polygoni multiflori, 20-25 parts of caulis spatholobi, 10-15 parts of rhizoma corydalis, 5-10 parts of frankincense, 5-10 parts of myrrh, 20-25 parts of herba lycopi, 20-25 parts of honeysuckle, 20-25 parts of salvia miltiorrhiza, 10-15 parts of selfheal, 15-20 parts of radix scrophulariae, 10-15 parts of angelica, 10-15 parts of cassia twig, 30-50 parts of astragalus mongholicus, 10-15 parts of monkshood, 5-10 parts of cinnamon and 5-10 parts of honey-fried licorice root.

Description

Traditional Chinese medicine for treating scleroderma

Technical Field

The invention relates to the field of medicines, in particular to a traditional Chinese medicine for treating scleroderma.

Background

Scleroderma, systemic sclerosis, is a disease that is clinically characterized by localized or diffuse thickening and fibrosis of the skin and may also affect the internal organs (heart, lungs, digestive tract, etc.). The disease is distributed worldwide, the prevalence rate is 50-300/100 ten thousands of population, and the incidence rate is 2.3-22.8/100 ten thousands per year. The peak age of onset is 30-50 years old, with women more than men. It is thought to be related to genetic and immune system dysfunction. The pathological features of the disease are wide vasculopathy, collagen proliferation and fibrosis of affected tissues. The change of skin is the characteristic of this disease and is symmetrical. Typical skin changes typically occur over three periods: swelling stage, hardening stage, and atrophy stage. Scleroderma can be divided into both localized and systemic types, depending on the degree to which the patient's skin appears to become hard, thick and atrophied, and where the lesions are affected. Localized scleroderma is mainly manifested by skin lesions, the internal organs are generally unaffected, and clinically, it is generally classified into scleroderma, scleroderma linear and scleroderma. Systemic scleroderma not only affects the skin, but also causes damage to multiple internal organs, also known as progressive systemic sclerosis. Clinically, the affected range of the skin is mainly used as a classification standard, and the skin is generally classified into two main categories of acral scleroderma and diffuse scleroderma in domestic dermatology. The limited scleroderma mostly changes the skin appearance of patients, and although the prognosis is better, the local scleroderma seriously affects the physical and mental health and the life quality of the patients, and becomes a social public health problem. Diffuse scleroderma is accompanied by visceral lesions, and has poor prognosis and high mortality. At present, no specific treatment means exists, western medicine treatment mainly aims at preventing the progress of diseases and advocating early diagnosis and early treatment, mainly comprises immunosuppressant and glucocorticoid, but no medicine can cure the disease, and the long-term administration of western medicine can generate drug resistance and a series of adverse reactions. Clinical practice has proved that traditional Chinese medicine has certain advantages in the aspect of treating scleroderma, so how to exert the advantages of traditional Chinese medicine, a safe and effective traditional Chinese medicine preparation is sought, the progress of the disease is controlled as soon as possible, complications and mortality are reduced, and the quality of life of scleroderma patients is improved, which is a new problem to be solved urgently in recent years.

Disclosure of Invention

In view of the above situation, the present invention aims to provide a Chinese medicine for treating scleroderma, which can effectively solve the problem of scleroderma medication.

Scleroderma belongs to the category of arthralgia syndrome in the traditional Chinese medicine, namely, skin is tight and hard, which belongs to the skin arthralgia syndrome in the traditional Chinese medicine, tendon and muscle are atrophic, and can not be bent and stretched, which belongs to the muscle arthralgia syndrome and the muscle arthralgia syndrome in the traditional Chinese medicine; joint soreness and contracture deformation belong to bone impediment in traditional Chinese medicine. Su Wen Bi Lun (plain questions and Bi Lun) cloud: wind-cold-dampness leading to qi deficiency also leads to arthralgia. … … five zang organs are combined, so they are also combined when they are not going for a long time. Therefore, bone impediment is complicated by pathogenic factors and is internally confined to the kidney. Failure of tendons and tendons, which are usually caused by the attack of pathogenic factors, enter the liver. The pulse is marked by disharmony, which is caused by the attack of pathogenic factors and enters the heart. Muscular paralysis, which is caused by the invasion of pathogenic factors, is internally retained in the spleen. The traditional Chinese medicine considers that the scleroderma is caused by insufficient healthy qi, external infection of damp-heat, impairment of yang by dampness, cold pertinence in the body, insecurity of defense and exterior, lack of closure of striae and skin and obstruction of qi and blood in the veins and blockage of the skin by three pathogenic factors of wind cold dampness. The early stage of the disease is mainly manifested as congealing cold in meridians, qi stagnation and blood stasis, and long-term disease causes pathogenic qi to be transmitted from meridians and collaterals, damaging healthy qi, further affecting viscera disorder, yang qi deficiency, and further aggravating pathological products such as phlegm coagulation and blood stasis. The disease is characterized by deficient nature and marked excess, and its pathogenesis can be summarized as cold congealing muscle striae, qi and blood stagnation, consuming qi and blood for a long time and disorder of viscera. Therefore, the treatment of this disease is mainly indicated for tonifying qi, activating yang, promoting blood circulation, removing blood stasis, clearing and activating the channels and collaterals. The principles of tonifying deficiency, dispelling cold and removing blood stasis should be applied when using the medicine, and especially the application of the medicine for promoting blood circulation and removing blood stasis should be paid attention to. So-called "removing stasis leads to the circulation of the meridians, qi and blood flow, and muscle nourishment and skin nourishment. Accordingly, the technical scheme of the invention is that the traditional Chinese medicine is prepared from the following raw material medicines in parts by weight: 10-15 parts of caulis polygoni multiflori, 20-25 parts of caulis spatholobi, 10-15 parts of rhizoma corydalis, 5-10 parts of frankincense, 5-10 parts of myrrh, 20-25 parts of herba lycopi, 20-25 parts of honeysuckle, 20-25 parts of salvia miltiorrhiza, 10-15 parts of selfheal, 15-20 parts of radix scrophulariae, 10-15 parts of angelica, 10-15 parts of cassia twig, 30-50 parts of astragalus mongholicus, 10-15 parts of monkshood, 5-10 parts of cinnamon and 5-10 parts of honey-fried licorice root, putting the raw materials in a pot special for decocting traditional Chinese medicines, adding water to immerse the raw materials, soaking the raw materials for 30min, decocting the raw materials for 2 times after soaking, firstly boiling the raw materials with strong fire, then decocting the raw materials with slow fire for 20-30min, and; and adding water into the rest liquid medicine and the residue, wherein the water content is 2-3cm higher than that of the residue, boiling with strong fire, decocting with slow fire for 15-20min, filtering to obtain 100-200ml liquid medicine, and mixing the first filtered liquid medicine and the second filtered liquid medicine.

The traditional Chinese medicine composition has the advantages of rich raw materials, simple preparation process, low price, convenience in taking and definite curative effect, and is an innovation in medicines for treating scleroderma.

Detailed Description

The following examples further illustrate the embodiments of the present invention in detail.

Example 1

The invention can be prepared from the following raw material medicaments in part by weight in specific implementation: 15 parts of caulis polygoni multiflori, 25 parts of caulis spatholobi, 12 parts of rhizoma corydalis, 9 parts of frankincense, 6 parts of myrrh, 25 parts of herba lycopi, 25 parts of honeysuckle, 25 parts of salvia miltiorrhiza, 15 parts of selfheal, 20 parts of radix scrophulariae, 15 parts of angelica, 15 parts of cassia twig, 30 parts of astragalus, 10 parts of monkshood, 5 parts of cinnamon and 10 parts of honey-fried licorice root, putting the raw materials into a pot special for decocting traditional Chinese medicines, adding water into the pot, immersing the raw materials for 30min, decocting the raw materials for 2 times after immersion, firstly decocting the raw materials with strong fire until the raw materials are boiled, then decocting the raw materials with slow fire for 20; decocting the rest medicinal liquid and residue with water content higher than 2cm, boiling with strong fire, decocting with slow fire for 15min, filtering to obtain medicinal liquid 100ml, and mixing the first and second filtered medicinal liquids.

Example 2

When the invention is implemented, the invention can also be prepared by the following raw material medicaments in part by weight: 12 parts of caulis polygoni multiflori, 23 parts of caulis spatholobi, 12 parts of rhizoma corydalis, 8 parts of frankincense, 7 parts of myrrh, 23 parts of herba lycopi, 22 parts of honeysuckle, 23 parts of salvia miltiorrhiza, 12 parts of selfheal, 18 parts of radix scrophulariae, 12 parts of angelica, 13 parts of cassia twig, 40 parts of astragalus mongholicus, 12 parts of monkshood, 8 parts of cinnamon and 7 parts of honey-fried licorice root, putting the raw materials in a pot special for decocting traditional Chinese medicines, adding water to immerse the raw materials, soaking the raw materials for 30min, decocting the raw materials for 2 times after soaking, firstly decocting the raw materials with strong fire until the raw materials are boiled, then decocting the raw; decocting the rest medicinal liquid and residue with water 2.5cm higher than the residue, boiling with strong fire, decocting with slow fire for 17min, filtering to obtain medicinal liquid 150ml, and mixing the first and second filtered medicinal liquids.

Example 3

When the invention is implemented, the invention can also be prepared by the following raw material medicaments in part by weight: 11 parts of caulis polygoni multiflori, 24 parts of caulis spatholobi, 11 parts of rhizoma corydalis, 6 parts of frankincense, 9 parts of myrrh, 21 parts of herba lycopi, 24 parts of honeysuckle, 21 parts of salvia miltiorrhiza, 11 parts of selfheal, 16 parts of radix scrophulariae, 11 parts of angelica, 11 parts of cassia twig, 49 parts of radix astragali, 14 parts of monkshood, 9 parts of cinnamon and 6 parts of honey-fried licorice root, putting the raw materials into a pot special for decocting traditional Chinese medicines, adding water to immerse the raw materials, soaking the raw materials for 30min, decocting the raw materials for 2 times after soaking, firstly decocting the raw materials with strong fire until the raw materials are boiled, then decocting the raw materials with; decocting the rest medicinal liquid and residue with water content higher than 3cm, boiling with strong fire, decocting with slow fire for 20min, filtering to obtain 200ml medicinal liquid, and mixing the first and second filtered medicinal liquids.

In the method of the invention:

caulis polygoni multiflori: sweet and neutral in nature. It enters liver and heart meridians. Has effects of nourishing blood, tranquilizing mind, dispelling pathogenic wind, and dredging collaterals, and can be used for treating blood deficiency, general pain, insomnia, dreaminess, rheumatalgia, skin prurigo, etc.

Caulis spatholobi: bitter, slightly sweet and warm. It enters liver meridian. Has effects of promoting blood circulation, replenishing blood, relaxing muscles and tendons, and activating collaterals. It is mainly used for treating menoxenia, dysmenorrhea, blood deficiency, amenorrhea, joint pain, limbs anesthesia, paralysis, and rheumatalgia.

Rhizoma corydalis: pungent, bitter and warm. It enters heart, liver and spleen meridians. Has the effects of promoting blood circulation, activating qi-flowing and relieving pain. It is mainly used for treating epigastric pain, hernia pain, dysmenorrhea, chest and hypochondriac pain, traumatic injury pain, thoracic obstruction, chest pain, etc.

Frankincense: pungent, bitter and warm. It enters heart, liver and spleen meridians. Has the effects of promoting blood circulation, relieving pain, eliminating swelling and promoting granulation. It is mainly used for treating dysmenorrhea, amenorrhea, epigastric pain, rheumatalgia, traumatic injury, carbuncle, cellulitis, swelling and pain, and intractable ulcer.

Myrrh: bitter and neutral. It enters heart, liver and spleen meridians. Has the effects of promoting blood circulation, relieving pain, eliminating swelling and promoting granulation. It is mainly used for treating dysmenorrhea, amenorrhea, epigastric pain, rheumatalgia, traumatic injury, carbuncle, cellulitis, swelling and pain, and intestinal abscess.

Herba lycopi: bitter and pungent with mild warm nature. It enters liver and spleen meridians. Has the functions of promoting blood circulation to disperse blood clots, promoting diuresis and eliminating swelling. It is mainly used for treating menoxenia, amenorrhea, dysmenorrhea, puerperal abdominal pain due to blood stasis, edema, etc.

Honeysuckle flower: sweet and cold. It enters lung, heart and stomach meridians. Has effects of clearing away heat and toxic materials, and dispelling pathogenic wind and heat. It is mainly used for treating sore, carbuncle, toxic swelling, affection of exogenous wind-heat, high fever, coma, and dysentery with blood due to toxic heat.

Red sage root: bitter and slightly cold. It enters heart and liver meridians. Has effects of promoting blood circulation, dispelling blood stasis, nourishing blood, tranquilizing mind, cooling blood, and relieving swelling. Is mainly used for irregular menstruation, dysmenorrhea, amenorrhea, postpartum abdominal stasis and pain, abdominal mass, arthralgia, traumatic injury, stasis and swelling, sores and ulcers, toxic swelling, coma and delirium, palpitation, severe palpitation, insomnia and the like.

Selfheal: bitter, pungent and cold. It enters liver and gallbladder meridians. Has effects of clearing away liver fire, removing toxic substance, and resolving hard mass. It is mainly used for conjunctival congestion, swelling and pain, headache, vertigo, scrofula, goiter, etc.

Radix scrophulariae: bitter, sweet, salty and cold. It enters lung, stomach and kidney meridians. Has the effects of clearing away heat and toxic materials and nourishing yin. It is mainly used for fever, dry mouth, coma, delirium, sore throat, carbuncle, swelling, sore, scrofula, subcutaneous nodule, etc.

Chinese angelica: sweet, pungent and warm. It enters liver, heart and spleen meridians. Has effects in replenishing blood, promoting blood circulation, regulating menstruation, relieving pain, and loosening bowel to relieve constipation. It is mainly used for treating blood deficiency manifested by sallow complexion, palpitation, insomnia, dysmenorrhea, amenorrhea, puerperal abdominal pain, arthralgia due to wind-cold-dampness, pain of limbs, traumatic injury, superficial infection, pyocutaneous disease, and constipation due to intestinal dryness.

Cassia twig: pungent, sweet and warm. It enters lung, kidney, heart and spleen meridians. Has effects of inducing sweat, relieving exterior syndrome, warming and dredging channels and collaterals, and warming and invigorating yang qi. It is mainly used for treating wind-cold type common cold, cold-dampness arthralgia syndrome, thoracic obstruction, puerperal abdominal pain, amenorrhea, dysmenorrhea, dysuresia, giddiness, edema, etc. Astragalus root: sweet and warm. It enters spleen and lung meridians. Has the effects of invigorating qi, invigorating yang, protecting health, consolidating exterior, inducing diuresis, relieving swelling, removing toxic substance, and promoting granulation. It is mainly used for qi deficiency and hypodynamia, anorexia and loose stool, collapse of middle-jiao energy, chronic diarrhea and rectocele, hematochezia and metrorrhagia, exterior deficiency and spontaneous perspiration, qi deficiency and edema, carbuncle, cellulitis and ulceration difficulty, chronic ulcer without astringency, blood deficiency with yellow skin, internal heat and diabetes.

Monkshood: pungent and hot meridians enter heart, kidney and spleen meridians. Has the effects of restoring yang, relieving collapse, invigorating fire, supporting yang, dispelling cold, and relieving pain. It is mainly used for treating spontaneous perspiration, cold limbs, aversion to cold, soreness of waist, weakness of feet, sexual impotence, abdominal pain, loose stool, dysuria, edema of limbs, palpitation, short breath, thoracic obstruction, and cardialgia.

Cinnamon: pungent, sweet and hot. It enters kidney, spleen, heart and liver meridians. Has the effects of tonifying fire, supporting yang, dispelling cold, relieving pain, and warming and dredging channels and collaterals. Is mainly used for treating aversion to cold, cold limbs, soreness and weakness of waist and knees, impotence, frequent micturition, anorexia, loose stool, cold-damp arthralgia, amenorrhea, dysmenorrhea, carbuncle, abscess, pus and non-ulcer.

Licorice root: sweet and neutral. It enters heart, lung, spleen and stomach meridians. Has the effects of invigorating spleen and replenishing qi, moistening lung for arresting cough, relieving spasm and pain, and relieving drug property. Is mainly used for treating weakness of spleen and stomach, shortness of breath, hypodynamia, anorexia, loose stool, cough, asthma, carbuncle, cellulitis, sore, pain, spasm of limbs, moderating drug property, and various medicines.

The traditional Chinese medicine preparation provided by the invention is a traditional Chinese medicine preparation taking 'qi tonifying, yang activating, blood circulation promoting, blood stasis removing, and meridian dredging and activating' as a treatment principle according to the holistic concept of treatment based on syndrome differentiation of traditional Chinese medicine, aims at the etiology and pathogenesis of the disease, is used for treatment from multiple targets and multiple ways based on the complexity of the disease, has the effects of clearing and activating the channels and collaterals, promoting blood circulation to remove blood stasis, warming and invigorating spleen and kidney, strengthening body resistance and eliminating pathogenic factors, can obviously improve the clinical symptoms and the life quality of scleroderma patients, delays the continuous development of the scleroderma patients, has the advantages of good compliance, stable curative effect, convenience in use, low price and the like, has a wide clinical application prospect, and obtains a satisfactory curative effect through clinical tests. The clinical data relating specifically to the present invention are as follows:

1. diagnostic criteria

Western diagnostic criteria: in 1980, the American college of rheumatology has diagnosis standard about the disease, and scleroderma can be diagnosed by one or two of the following main standards.

The main standards are as follows: proximal scleroderma, i.e., the skin of any area above the finger and metacarpophalangeal or metatarsophalangeal joints, is symmetrically thickened, stretched and hardened. Such changes can involve the entire limb, face, neck and torso (chest and abdomen). Secondary criteria: the standard chest film for fibrosis of the lung bases at both sides shows net-shaped linear or linear nodular shadows at both sides, and the lung bases are most obvious and can present diffuse ground glass shadows or honeycomb lung appearances. These changes cannot be attributed to primary lung lesions. ② the above-mentioned skin changes are limited to fingers. And the disappearance of the dented scar of the finger or the tissues of the finger pad and the tissues of the fingertip pad (finger belly) caused by ischemia.

The traditional Chinese medicine diagnosis standard is as follows: reference is made to the skin arthralgia traditional Chinese medicine syndrome type diagnosis standard formulated by the Chinese medicine society of 2012, "diagnosis and treatment guidelines for common diseases of dermatology of traditional Chinese medicine.

Obstruction of wind-damp arthralgia: in the early stage of the disease, the skin is edema, the dermatoglyph disappears, the skin is tense and thick, the skin is not sunken, the color is pale or yellowish brown, the surface temperature is low, the self feels stabbing pain or numbness, the acral ends are purplish and pale, and the skin becomes worse when being in cold or excited by mood.

Inclusion criteria were: the method conforms to the Western medicine diagnosis standard of scleroderma; ② the Chinese traditional syndrome diagnosis standard of skin arthralgia is satisfied; ③ scleroderma patients of 18-60 years old and male and female; fourthly, no medicine influencing the judgment of the test result is used within two months; patient informed consent.

Exclusion criteria: women in gestation or lactation; ② serious patients with bad liver and kidney functions and other serious diseases such as digestion, respiration and circulatory system; patients who have used glucocorticoid in nearly two months;

case conditions all cases originated from the applicant's outpatient department, affiliated hospital, etc. 60 scleroderma patients are selected, and divided into 30 Chinese and western medicines and 30 simple western medicines at random. Age 30-55 years, with 52 women and 8 men; the course of disease is 0.6-10 years.

Treatment regimens

The Chinese and western medicines are combined to take the Chinese medicinal preparation and the prednisone for oral administration, and the dosage is the same as that of the simple western medicine. The traditional Chinese medicine is taken once in the morning and at night, each time is 100-200ml, 4 weeks are taken as a treatment course, and the medicine is continuously taken for 6 treatment courses.

Pure western medicine group: prednisone, 40mg every other day, 2.5mg subtracted weekly until discontinued.

Standard of therapeutic effect

Refer to the Chinese medicine syndrome curative effect judgment standard established by the national traditional Chinese medicine administration of 1994.

The clinical cure is as follows: the hardened and atrophied skin, local skin color of lesion, dysfunction and fallen hair are recovered to be normal or basically recovered to 95 percent or more;

the effect is shown: the whole improvement of skin sclerosis, atrophy, pigmentation and dysfunction is 70 percent or more, but less than 95 percent;

the method has the following advantages: the whole improvement of skin sclerosis, atrophy, pigmentation and dysfunction is 30% or more, but less than 70%:

and (4) invalidation: the overall improvement of skin sclerosis, atrophy, pigmentation, dysfunction is less than 30% or no improvement or deterioration.

Statistical effect

The results of the treatment are shown in Table 1

TABLE 1 comparison of the two therapeutic effects

Adverse reactions: no obvious adverse reactions occurred in both groups during the treatment period.

Conclusion

The conditions show that the traditional Chinese medicine composition has the advantages of strict and scientific formula, abundant raw materials, safe administration, stability and reliability, can control the progress of scleroderma, prevent the enlargement of lesion skin area, has good effect on scleroderma treatment, has no adverse reaction and side effect through clinical verification, is an innovation for scleroderma treatment medicines, and has practical clinical significance.

Claims

1. The traditional Chinese medicine for treating rheumatic arthralgia syndrome scleroderma is characterized by being prepared from the following raw material medicines in parts by weight: 10-15 parts of caulis polygoni multiflori, 20-25 parts of caulis spatholobi, 10-15 parts of rhizoma corydalis, 5-10 parts of frankincense, 5-10 parts of myrrh, 20-25 parts of herba lycopi, 20-25 parts of honeysuckle, 20-25 parts of salvia miltiorrhiza, 10-15 parts of selfheal, 15-20 parts of radix scrophulariae, 10-15 parts of angelica, 10-15 parts of cassia twig, 30-50 parts of astragalus mongholicus, 10-15 parts of monkshood, 5-10 parts of cinnamon and 5-10 parts of honey-fried licorice root, putting the raw materials in a pot special for decocting traditional Chinese medicines, adding water to immerse the raw materials, soaking the raw materials for 30min, decocting the raw materials for 2 times after soaking, firstly boiling the raw materials with strong fire, then decocting the raw materials with slow fire for 20-30min, and; and adding water into the rest liquid medicine and the residue, wherein the water content is 2-3cm higher than that of the residue, boiling with strong fire, decocting with slow fire for 15-20min, filtering to obtain 100-200ml liquid medicine, and mixing the first filtered liquid medicine and the second filtered liquid medicine.

2. The traditional Chinese medicine for treating rheumatic arthralgia syndrome scleroderma according to claim 1, which is prepared from the following raw medicines in parts by weight: 15 parts of caulis polygoni multiflori, 25 parts of caulis spatholobi, 12 parts of rhizoma corydalis, 9 parts of frankincense, 6 parts of myrrh, 25 parts of herba lycopi, 25 parts of honeysuckle, 25 parts of salvia miltiorrhiza, 15 parts of selfheal, 20 parts of radix scrophulariae, 15 parts of angelica, 15 parts of cassia twig, 30 parts of astragalus, 10 parts of monkshood, 5 parts of cinnamon and 10 parts of honey-fried licorice root, putting the raw materials into a pot special for decocting traditional Chinese medicines, adding water into the pot, immersing the raw materials for 30min, decocting the raw materials for 2 times after immersion, firstly decocting the raw materials with strong fire until the raw materials are boiled, then decocting the raw materials with slow fire for 20; decocting the rest medicinal liquid and residue with water content higher than 2cm, boiling with strong fire, decocting with slow fire for 15min, filtering to obtain medicinal liquid 100ml, and mixing the first and second filtered medicinal liquids.

3. The traditional Chinese medicine for treating rheumatic arthralgia syndrome scleroderma according to claim 1, which is prepared from the following raw medicines in parts by weight: 12 parts of caulis polygoni multiflori, 23 parts of caulis spatholobi, 12 parts of rhizoma corydalis, 8 parts of frankincense, 7 parts of myrrh, 23 parts of herba lycopi, 22 parts of honeysuckle, 23 parts of salvia miltiorrhiza, 12 parts of selfheal, 18 parts of radix scrophulariae, 12 parts of angelica, 13 parts of cassia twig, 40 parts of astragalus mongholicus, 12 parts of monkshood, 8 parts of cinnamon and 7 parts of honey-fried licorice root, putting the raw materials in a pot special for decocting traditional Chinese medicines, adding water to immerse the raw materials, soaking the raw materials for 30min, decocting the raw materials for 2 times after soaking, firstly decocting the raw materials with strong fire until the raw materials are boiled, then decocting the raw; decocting the rest medicinal liquid and residue with water 2.5cm higher than the residue, boiling with strong fire, decocting with slow fire for 17min, filtering to obtain medicinal liquid 150ml, and mixing the first and second filtered medicinal liquids.

4. The traditional Chinese medicine for treating rheumatic arthralgia syndrome scleroderma according to claim 1, which is prepared from the following raw medicines in parts by weight: 11 parts of caulis polygoni multiflori, 24 parts of caulis spatholobi, 11 parts of rhizoma corydalis, 6 parts of frankincense, 9 parts of myrrh, 21 parts of herba lycopi, 24 parts of honeysuckle, 21 parts of salvia miltiorrhiza, 11 parts of selfheal, 16 parts of radix scrophulariae, 11 parts of angelica, 11 parts of cassia twig, 49 parts of radix astragali, 14 parts of monkshood, 9 parts of cinnamon and 6 parts of honey-fried licorice root, putting the raw materials into a pot special for decocting traditional Chinese medicines, adding water to immerse the raw materials, soaking the raw materials for 30min, decocting the raw materials for 2 times after soaking, firstly decocting the raw materials with strong fire until the raw materials are boiled, then decocting the raw materials with; decocting the rest medicinal liquid and residue with water content higher than 3cm, boiling with strong fire, decocting with slow fire for 20min, filtering to obtain 200ml medicinal liquid, and mixing the first and second filtered medicinal liquids.