CN109091533A - Chinese medicine composition and preparation method thereof for treating acute tonsillitis - Google Patents
Chinese medicine composition and preparation method thereof for treating acute tonsillitis Download PDFInfo
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Abstract
The present invention relates to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition and preparation method thereof for treating acute tonsillitis.For treating the Chinese medicine composition of acute tonsillitis, in parts by weight comprising Radix Astragali 1-20 parts of 1-10 parts of schizonepeta, 1-10 parts of radix saposhnikoviae, 1-10 parts of Rhizoma Et Radix Notopterygii, 1-10 parts of Radix Angelicae Sinensis, 1-10 parts of the root of Dahurain angelica, 1-9 parts of radices trichosanthis, 1-10 parts of spina gleditsiae, 1-12 parts of campanulaceae, 1-10 parts of great burdock achene and life.Its pharyngalgia that can quickly bring down a fever and eliminate acts on the reduction that leucocyte and CRP increase significant.
Description
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition for treating acute tonsillitis and its
Preparation method.
Background technique
Children acute tonsillitis is pediatric common disease, is caused by various pathogens, can cause the infection of the upper respiratory tract, one
Determining degree will appear lymphoid tissue enlargement, bottleneck throat mucosa hemorrhage, acute inflammatory response etc..Infant onset speed is especially fast, disease
Feelings development is swift and violent, if failing timely and effectively therapy intervention, it is possible to cause the infection of adjacent organs, health causes serious
It influences.Paediatric acute tonsillitis onset is rapid and higher in winter-spring season disease incidence, and infant is in addition to often there is tonsillotome redness
Outside, separately can with a degree of pharynx mucous membrane and pharynx lymphoid tissue enlargement, with the progress of the infant state of an illness, infant can concurrent kidney it is small
Ball ephritis has seriously threatened the health of infant, needs effectively to be treated in time.It is right at present in general hospital of China
The western medicine of paediatric acute tonsillitis mainly uses antibiotic treatment for main means, such as penicillin, cefathiamidine, right
Recurrent exerbation person can carry out surgical resection tonsillotome.Doctor trained in Western medicine merely anti-inflammatory symptomatic treatment produce effects it is also obvious, but in recent years
Carry out being widely used for China's antibiotic, many infants are higher to more antibiotic resistance, and have part infant to resist infusion
Treatment, selecting tcm treatment according to syndrome differentiation is preferable treatment method.
Summary of the invention
The purpose of the present invention is to provide a kind of for treating the Chinese medicine composition of acute tonsillitis, can quickly move back
Heat and elimination pharyngalgia act on the reduction that leucocyte and CRP increase significant.
Another object of the present invention is to provide a kind of for treating the preparation side of the Chinese medicine composition of acute tonsillitis
Method, this method is easy to operate, and operating condition easily reaches, and preparation cost is cheap, is convenient for expanding production.
The present invention solves its technical problem and adopts the following technical solutions to realize:
The present invention propose it is a kind of for treating the Chinese medicine composition of acute tonsillitis, in parts by weight comprising schizonepeta
1-10 parts, 1-10 parts of radix saposhnikoviae, 1-10 parts of Rhizoma Et Radix Notopterygii, 1-10 parts of Radix Angelicae Sinensis, 1-10 parts of the root of Dahurain angelica, 1-9 parts of radices trichosanthis, 1-10 parts of spina gleditsiae,
Radix Astragali 1-20 parts of 1-12 parts of campanulaceae, 1-10 parts of great burdock achene and life.
The present invention proposes a kind of preparation method, comprising the following steps: by schizonepeta, radix saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, the root of Dahurain angelica, smallpox
Powder, spina gleditsiae, campanulaceae, great burdock achene and raw Radix Astragali are boiled.
The beneficial effect of the Chinese medicine composition for treating acute tonsillitis of the embodiment of the present invention is: the present invention provides
Chinese medicine composition by schizonepeta, Rhizoma Et Radix Notopterygii, radix saposhnikoviae interaction altogether be monarch drug in a prescription, can inducing diaphoresis dampness elimination, great burdock achene, the root of Dahurain angelica, campanulaceae,
Spina gleditsiae and when being classified as ministerial drug, can dampness elimination detumescence, detoxicating and resolving a mass, radices trichosanthis and raw Radix Astragali are that adjuvant can be thoroughly evil with righting,
Enhance resistance of human body, final realize quickly brings down a fever, reduces swelling, and guarantees the low effect of poisonous side effect of medicine.And pass through above-mentioned limit
Determine the proportion of drug, can be further ensured that the curative effect of drug.The preparation method of above-mentioned Chinese medicine composition is simple, and active constituent contains
Amount is suitable for guaranteeing the therapeutic effect of medicament.
Specific embodiment
It in order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below will be in the embodiment of the present invention
Technical solution be clearly and completely described.The person that is not specified actual conditions in embodiment, according to normal conditions or manufacturer builds
The condition of view carries out.Reagents or instruments used without specified manufacturer is the conventional production that can be obtained by commercially available purchase
Product.
In the description of the present invention, it should be noted that term " first ", " second " etc. are only used for distinguishing description, without
It can be interpreted as indication or suggestion relative importance.
The Chinese medicine composition and preparation method thereof for treating acute tonsillitis of the embodiment of the present invention is carried out below
It illustrates.
Chinese medicine thinks that acute tonsillitis category " acute tonsillitis " scope is invaded mainly due to affection by exopathogenic cold-windization heat or wind-heat cult poison
Body enters to invade lung, stomach from mouth and nose, most ends in throat and fall ill.Meanwhile children are the body of easily empty easily reality, and development is not filled
Point, therefore, formula will be based on gentle.And doctor trained in Western medicine removes inflammation using antibiotic such as penicillin, is easy to produce drug resistance, and poison
Side effect is larger, and the cold inducing diaphoresis Chinese medicine therapeutic effect of general hair is bad.
Therefore, on this basis, the present inventor provides a kind of for treating the Chinese medicine composition of acute tonsillitis, the group
It closes object and is better than application for the treatment of paediatric acute tonsillitis.Specifically, in parts by weight comprising 1-10 parts of schizonepeta, radix saposhnikoviae 1-
10 parts, 1-10 parts of Rhizoma Et Radix Notopterygii, 1-10 parts of Radix Angelicae Sinensis, 1-10 parts of the root of Dahurain angelica, 1-9 parts of radices trichosanthis, 1-10 parts of spina gleditsiae, 1-12 parts of campanulaceae, ox
Radix Astragali 1-20 parts of 1-10 parts of burdock and life.Or Chinese medicine composition includes 2-8 parts of schizonepeta, 2-8 parts of radix saposhnikoviae, 2-8 parts of Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis
Radix Astragali 5-15 parts of 2-8 parts, 2-8 parts of the root of Dahurain angelica, 2-6 parts of radices trichosanthis, 2-8 parts of spina gleditsiae, 2-10 parts of campanulaceae, 2-8 parts of great burdock achene and life.
Or Chinese medicine composition includes 4-6 parts of schizonepeta, 4-6 parts of radix saposhnikoviae, 4-6 parts of Rhizoma Et Radix Notopterygii, 4-6 parts of Radix Angelicae Sinensis, 4-6 parts of the root of Dahurain angelica, radices trichosanthis 3-5
Part, 4-6 parts of spina gleditsiae, 4-6 parts of campanulaceae, 4-6 parts of great burdock achene and Radix Astragali 8-12 parts of life.
Firstly, can dissipate the cold-evil of exogenous disease outside using above-mentioned formula, the swelling and pain of interior scattered throat, then hit the interpretation of the cause, onset and process of an illness, quickly
Good therapeutic effect is obtained, and is interacted between the prescription drug, so that the medicinal peace of formula, and side effect is low.And match
Drug in side can be further ensured that having quickly and good therapeutic effect for formula using aforementioned proportion, if in formula
The proportion of drug changes, and therapeutic effect is easy to cause to change.
In this formula schizonepeta, Rhizoma Et Radix Notopterygii, radix saposhnikoviae interaction altogether be monarch drug in a prescription, can inducing diaphoresis dampness elimination, great burdock achene, the root of Dahurain angelica, tangerine
Stalk, spina gleditsiae and when being classified as ministerial drug, can dampness elimination detumescence, detoxicating and resolving a mass, radices trichosanthis and raw Radix Astragali are that adjuvant can be saturating with righting
Heresy enhances resistance of human body.
Schizonepeta is the dry aerial parts of Lamiaceae plant schizonepeta Schizonepeta tenuifolia Briq..Taste
It is pungent, slightly warm in nature.With inducing diaphoresis relieve heat, promoting eruption and disappear sore the effect of, it mainly plays its inducing diaphoresis relieve heat in embodiments of the present invention
Effect.
Radix saposhnikoviae, alias copper rue, return grass, hundred, hundred kinds at Hui Yun.Acrid flavour, sweet, slightly warm in nature.It expels pathogenic wind from the body surface, expel endogenous wind to relieve convulsion,
The effect of relieving convulsion, radix saposhnikoviae can share inducing diaphoresis with schizonepeta and Rhizoma Et Radix Notopterygii and dry in the present embodiment.
Rhizoma Et Radix Notopterygii, Chinese medicine name.Alias Qiang is green, shield Qiang envoy, Hu king envoy, Qiang is sliding, moves back wind envoy, black powder, Umbelliferae, Rhizoma Et Radix Notopterygii
Platymiscium.Acrid flavour, hardship, it is warm-natured.With relieving exterior syndrome and dispelling cold, the effect of expelling wind and eliminating dampness, analgesic.In embodiments of the present invention, can
Inducing diaphoresis dampness elimination.
Radix Angelicae Sinensis is the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.It is sweet in flavor, pungent, property
Temperature.With replenishing and activating blood, the effect of regulating menstruation and relieving pain, moistening intestines and relaxing bowels.Its effect is detoxicating and resolving a mass in embodiments of the present invention.
The root of Dahurain angelica, Chinese medicine name.Acrid flavour, it is warm-natured.With relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, clearing the nasal passage, eliminating dampness stops band, detumescence and apocenosis,
Dispelling wind and arresting itching.Its effect is detumescence in embodiments of the present invention.
Radices trichosanthis, Chinese medicine name.Sweet, slight bitter, it is slightly cold.It with clearing heat-fire, promotes the production of body fluid to quench thirst, the benefits of detumescence and apocenosis.In this hair
Radices trichosanthis is can to share with Radix Astragali in bright embodiment, and righting is thoroughly evil, removes toxin, promotes resistance of human body, and reduce drug
Side effect.
Spina gleditsiae, Chinese medicine name.For the drying quil of leguminous plant Chinese honey locust Gleditsia sinensis Lam..Acrid flavour, property
Temperature.With detumescence and poison retention, the effect of apocenosis, desinsection.It can reduce swelling in embodiments of the present invention.
Campanulaceae, Chinese medicine name.For the drying of Campanulaceae campanulaceae Platycodon grandiflorus (Jacq.) A.Dc.
Root.It is bitter, pungent, it is mild-natured.With promoting the dispersing function of the lung, the effect of relieving sore-throat, eliminating the phlegm, apocenosis, it can reduce swelling in embodiments of the present invention.
Great burdock achene, Chinese medicine name.For the dry mature fruit of composite family biennial herb plant fructus arctii.Its is pungent, bitter, trembles with fear, has
The effect of dispelling wind and heat from the body, promoting the dispersing function of the lung relieving sore-throat, promoting eruption of detoxifying, sore is treated in detumescence, it can be used as ministerial drug in embodiments of the present invention, and white
The root of Dahurian angelica, great burdock achene and spina gleditsiae share dampness elimination detumescence dampness elimination
Raw Radix Astragali, Chinese medicine name.This product is the root of leguminous mongolian scutellaria.It is warm-natured, it is sweet in flavor.Invigorating qi for strengthening superficies, eliminating toxic row
Purulence, diuresis, myogenic.It can share with radices trichosanthis and strengthen the body resistance to consolidate the constitution in embodiments of the present invention, thoroughly evil, reduce the secondary of drug and make
With.
Further, when the temperature of patient is higher than 38.5 DEG C, which further includes 6-18 parts of gypsum.Gypsum
With clearing heat-fire, relieving restlessness is quenched the thirst, restrain myogenic the benefits of, in embodiments of the present invention, effect be can further speed up it is scattered
Thermal effect.
The embodiment of the present invention also provide it is a kind of for treating the preparation method of the Chinese medicine composition of acute tonsillitis, including
Following steps:
Schizonepeta, radix saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, the root of Dahurain angelica, radices trichosanthis, spina gleditsiae, campanulaceae, great burdock achene and raw Radix Astragali are boiled.
Specifically, schizonepeta, radix saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, the root of Dahurain angelica, radices trichosanthis, spina gleditsiae, campanulaceae, great burdock achene and raw Radix Astragali are broken
It is mixed after being broken into small cube, is being broken into small cube after can also mixing, be broken into small cube convenient in each bulk pharmaceutical chemicals
Active constituent dissolution, meanwhile, also there will not be the presence of the solid dregs of a decoction when collecting medical fluid, promote medicament swallows sense.
The mixture that then above-mentioned raw materials are mixed to get is mixed with water, corresponds to 6-12 volume according to every part of mixture
The ratio of water mixed, when representing every gram for every part, corresponding 7-12 milliliters of water then carry out being heated to boiling using intense fire
It rises, recycles the 15-17% for decocting with slow fire the volume for only having original solution to liquor capacity.
Intense fire refers to that firepower is big and anxious, due to the prolonged infusion of drug, is easy to cause active constituent rotten, meanwhile, it waves
The substance of hair property largely volatilizees, and therefore, quickly is heated to boiling by mixed solution using intense fire, shortens heating time, reduces
Active constituent goes bad and the amount of volatile component volatilization, then guarantees the drug effect of formula.And mild fire refers to small and slow fire, makes
It obtains mixed solution and remains slightly boiled state, active constituent is more constantly dissolved in water.And solution is endured into value
The 15-17% of original solution controls the content of active constituent in solution, so that activity component concentration is suitable for, then guarantees formula
There is good therapeutic effect.
It is then filtered to obtain filtrate and the dregs of a decoction, the dregs of a decoction and water is then added to the water of 4-6 volume according to every part of dregs of a decoction
It is mixed, then carries out infusion.And the obtained volume of solution of infusion is the 10-15% of original solution volume.
Carrying out an infusion again is to promote the utilization of raw material to further extract the active constituent in raw material
Rate, while guaranteeing the content of active constituent in medicament, guarantee therapeutic effect.
Medication is respectively at early, middle and late postprandial 1 hour, and once a dose.6d is 1 course for the treatment of, evaluates curative effect after even served 2 courses for the treatment of.
And pediatric dose is every year old daily crude drug 1g.
Feature and performance of the invention are described in further detail with reference to embodiments.
Embodiment 1
It is provided in this embodiment for treating the Chinese medicine composition of acute tonsillitis comprising schizonepeta 1g, radix saposhnikoviae 10g,
Rhizoma Et Radix Notopterygii 1g, Radix Angelicae Sinensis 1g, root of Dahurain angelica 10g, radices trichosanthis 9g, spina gleditsiae 10g, campanulaceae 12g, great burdock achene 1g and raw Radix Astragali 1g.
The present embodiment also provides a kind of for treating the preparation method of the Chinese medicine composition of acute tonsillitis including following
Step:
Schizonepeta, radix saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, the root of Dahurain angelica, radices trichosanthis, spina gleditsiae, campanulaceae, great burdock achene and raw Radix Astragali are crushed respectively
At fritter, then remix to obtain mixture.
Mixture is mixed with 336 milliliters of water then, then is heated to boiling using intense fire, then recycles mild fire
It is heated to being filtered after solution is 50.5 milliliters, filtrate and the dregs of a decoction is obtained by filtration.
Then the dregs of a decoction are mixed with 280 milliliters of water, and infusion again, and infusion to liquor capacity is 42 milliliters.Finally will
The solution that above-mentioned infusion twice obtains is mixed.
Embodiment 2
It is provided in this embodiment for treating the Chinese medicine composition of acute tonsillitis comprising schizonepeta 10g, radix saposhnikoviae 1g,
Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Sinensis 10g, root of Dahurain angelica 1g, radices trichosanthis 1g, spina gleditsiae 1g, campanulaceae 1g, great burdock achene 10g and raw Radix Astragali 20g.
The present embodiment also provides a kind of for treating the preparation method of the Chinese medicine composition of acute tonsillitis including following
Step:
After schizonepeta, radix saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, the root of Dahurain angelica, radices trichosanthis, spina gleditsiae, campanulaceae, great burdock achene and raw Radix Astragali are mixed again
It is ground into fritter, obtains mixture.
Mixture is mixed with 650 milliliters of water then, then is heated to boiling using intense fire, then recycles mild fire
It is heated to being filtered after solution is 110.5 milliliters, filtrate and the dregs of a decoction is obtained by filtration.
Then the dregs of a decoction are mixed with 325 milliliters of water, and infusion again, and infusion to liquor capacity is 49 milliliters.Finally will
The solution that above-mentioned infusion twice obtains is mixed.
Embodiment 3
The Chinese medicine composition provided in this embodiment for being used to treat acute tonsillitis comprising schizonepeta 2g, radix saposhnikoviae 2g, Qiang
2g, Radix Angelicae Sinensis 2g, root of Dahurain angelica 2g, radices trichosanthis 2g, spina gleditsiae 2g, campanulaceae 2g, great burdock achene 2g and raw Radix Astragali 5g living.
The present embodiment also provides a kind of for treating the preparation method of the Chinese medicine composition of acute tonsillitis including following
Step:
Schizonepeta, radix saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, the root of Dahurain angelica, radices trichosanthis, spina gleditsiae, campanulaceae, great burdock achene and raw Radix Astragali are crushed respectively
At fritter, then remix to obtain mixture.
Mixture is mixed with 276 milliliters of water then, then is heated to boiling using intense fire, then recycles mild fire
It is heated to being filtered after solution is 44 milliliters, filtrate and the dregs of a decoction is obtained by filtration.
Then the dregs of a decoction are mixed with 138 milliliters of water, and infusion again, and infusion to liquor capacity is 18 milliliters.Finally will
The solution that above-mentioned infusion twice obtains is mixed.
Embodiment 4
The Chinese medicine composition provided in this embodiment for being used to treat acute tonsillitis comprising schizonepeta 8g, radix saposhnikoviae 8g, Qiang
9g, Radix Angelicae Sinensis 8g, root of Dahurain angelica 8g, radices trichosanthis 6g, spina gleditsiae 8g, campanulaceae 10g, great burdock achene 8g and raw Radix Astragali 15g living.
The present embodiment also provides a kind of for treating the preparation method of the Chinese medicine composition of acute tonsillitis including following
Step:
Schizonepeta, radix saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, the root of Dahurain angelica, radices trichosanthis, spina gleditsiae, campanulaceae, great burdock achene and raw Radix Astragali are crushed respectively
At fritter, then remix to obtain mixture.
Mixture is mixed with 790 milliliters of water then, then is heated to boiling using intense fire, then recycles mild fire
It is heated to being filtered after solution is 119 milliliters, filtrate and the dregs of a decoction is obtained by filtration.
Then the dregs of a decoction are mixed with 352 milliliters of water, and infusion again, and infusion to liquor capacity is 35.5 milliliters.Finally
The solution that above-mentioned infusion twice obtains is mixed.
Embodiment 5
The Chinese medicine composition provided in this embodiment for being used to treat acute tonsillitis comprising schizonepeta 6g, radix saposhnikoviae 6g, Qiang
6g, Radix Angelicae Sinensis 4g, root of Dahurain angelica 4g, radices trichosanthis 3g, spina gleditsiae 4g, campanulaceae 4g, great burdock achene 4g and raw Radix Astragali 12g living.
The present embodiment also provides a kind of for treating the preparation method of the Chinese medicine composition of acute tonsillitis including following
Step:
Schizonepeta, radix saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, the root of Dahurain angelica, radices trichosanthis, spina gleditsiae, campanulaceae, great burdock achene and raw Radix Astragali are crushed respectively
At fritter, then remix to obtain mixture.
Mixture is mixed with 371 milliliters of water then, then is heated to boiling using intense fire, then recycles mild fire
It is heated to being filtered after solution is 60 milliliters, filtrate and the dregs of a decoction is obtained by filtration.
Then the dregs of a decoction are mixed with 239 milliliters of water, and infusion again, and infusion to liquor capacity is 27 milliliters.Finally will
The solution that above-mentioned infusion twice obtains is mixed.
Embodiment 6
The Chinese medicine composition provided in this embodiment for being used to treat acute tonsillitis comprising schizonepeta 4g, radix saposhnikoviae 4g, Qiang
4g, Radix Angelicae Sinensis 6g, root of Dahurain angelica 6g, radices trichosanthis 5g, spina gleditsiae 6g, campanulaceae 6g, great burdock achene 6g and raw Radix Astragali 8g living.
The present embodiment also provides a kind of for treating the preparation method of the Chinese medicine composition of acute tonsillitis including following
Step:
Schizonepeta, radix saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, the root of Dahurain angelica, radices trichosanthis, spina gleditsiae, campanulaceae, great burdock achene and raw Radix Astragali are crushed respectively
At fritter, then remix to obtain mixture.
Mixture is mixed with 605 milliliters of water then, then is heated to boiling using intense fire, then recycles mild fire
It is heated to being filtered after solution is 91 milliliters, filtrate and the dregs of a decoction is obtained by filtration.
Then the dregs of a decoction are mixed with 300 milliliters of water, and infusion again, and infusion to liquor capacity is 33 milliliters.Finally will
The solution that above-mentioned infusion twice obtains is mixed.
Embodiment 7
The Chinese medicine composition provided in this embodiment for being used to treat acute tonsillitis comprising schizonepeta 5g, radix saposhnikoviae 5g, Qiang
5g, Radix Angelicae Sinensis 5g, root of Dahurain angelica 5g, radices trichosanthis 4g, spina gleditsiae 5g, campanulaceae 5g, great burdock achene 5g and raw Radix Astragali 10g living.
The present embodiment also provides a kind of for treating the preparation method of the Chinese medicine composition of acute tonsillitis including following
Step:
Schizonepeta, radix saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, the root of Dahurain angelica, radices trichosanthis, spina gleditsiae, campanulaceae, great burdock achene and raw Radix Astragali are crushed respectively
At fritter, then remix to obtain mixture.
Mixture is mixed with 432 milliliters of water then, then is heated to boiling using intense fire, then recycles mild fire
It is heated to being filtered after solution is 70 milliliters, filtrate and the dregs of a decoction is obtained by filtration.
Then the dregs of a decoction are mixed with 297 milliliters of water, and infusion again, and infusion to liquor capacity is 39 milliliters.Finally will
The solution that above-mentioned infusion twice obtains is mixed.
Embodiment 8-10
The formula of the Chinese medicine composition that embodiment 8-10 is provided and the Chinese medicine composition that embodiment 1 provides is almost the same, area
It is not that embodiment 8 adds gypsum 6g, embodiment 9 adds gypsum 18g, and embodiment 10 adds gypsum 12g.
Comparative example 1: cefaclor chewable tablet
Experimental example
Selection patient is divided into two groups, and one group is observation group, and one group is control group, and observation group takes in 3 infusion of embodiment
Drug composition, control group take the drug of comparative example 1.On the basis of 2 groups of patients give conventional base nursing, 6d is 1 treatment
Journey, 2 courses for the treatment of of medication.The pretherapy and post-treatment symptom of patient, the variation of sign and record are observed, detection blood routine, c reactive protein are horizontal
Variation.
Research object: selected from October, 2015 in December, 2017 in the attached hospital of traditional Chinese hospital Hui Yi of Ningxia Medical University Yinchuan
The patient of hospital；Meet diagnostic criteria, and the patient of age ≤15 year old is as the case subjects for being included in research.Observation group male 22
Example, female 19, the median age 8.1 years old；Control group male 21, female 18, the median age 7.9 years old.2 groups of infants gender, the age,
Course of disease etc. no significant difference (P > 0.05), is comparable.Ratify through Medical Ethics Committee, signature is known
Feelings letter of consent.
Western medicine diagnostic criteria: referring to " the clinic diagnosis guide ENT & HN Surgery Dept. of Chinese Medical Association chief editor in 2009
Fascicle " in for " acute tonsillitis " diagnostic criteria.
A, constitutional symptom: onset is anxious, can there is chilly, shiver with cold, high fever, loss of appetite, fatigue and weak.
B, local symptom: with pharyngalgia it is obvious based on, ear is often emitted to, with dysphagia.If lower neck lymph node
There is enlargement person, is often accompanied by the performance of rotary head inconvenience.
C, physical examination: face of acute ill.Congestion of throat, position the most serious are tonsillotome and two one or both sides almonds
Body enlargement, the visible pus point in surface, color are yellow, white or yellow-white, can there is bean dregs sample exudate at crypts mouth, may
It can join together to form pseudomembrane, lower neck lymph node is it is possible that enlargement.
D, auxiliary examination: WBC and N% is increased in blood analysis.
Tcm diagnosis standard: " the TCM E.N.T. Dept. disease diagnosis treatment write for 1994 referring to State Administration of Traditional Chinese Medicine
Criterion is quasi- " and 2012 China Association of Traditional Chinese Medicine chief editor " the common disease practice guidelines of Chinese medicine hals,Nasen und Ohrenheilkunde " in about " anxious newborn
The diagnostic criteria of moth ".
A, it medical history: can suffer from cold, fatigue, common cold history.
B, clinical symptoms: onset is anxious, pharyngalgia, dysphagia.It can be poor, out of strength etc. with fever, aversion to cold, shiver with cold, food.
C, toposcopy: tonsillotome is congested red and swollen, and surface can have pus point, and the corrosion of serious person's pus point is in blocks.
Lymphoodi mandibulares are it is possible that enlargement.
D, other are checked: blood analysis finds that WBC is increased, and N% increases.
It is included in standard: 1. meeting acute tonsillitis Western medicine diagnostic criteria；2. meeting acute tonsillitis tcm diagnosis and dialectical mark
It is quasi-；3. one full year of life at age 1-14, male or female.
Exclusion criteria: 1. all do not meet is included in standard person；2. the age<1 one full year of life or>14 one full year of life persons；3. being associated with may draw
Play the disease that total white blood cells or neutrophil leucocyte increase；4. being associated with other respiratory disease persons；5. merge intentionally, liver,
The organs such as kidney seriously damage the wounded；6. other are not suitable for being included in researcher.
Therapeutic scheme: observation group was respectively at early, middle and late postprandial 1 hour, the medicament for tanning that once a dose, and dose is identical.
6d is 1 course for the treatment of, evaluates curative effect after even served 2 courses for the treatment of.Control group is according to following administrations: weight < 25kg, 10mg/kg；Weight
>=25kg, each 0.25g, 3 times a day.
Efficacy evaluation: effectively: heat is moved back, and pharyngalgia disappears, and tonsillotome restores normal, WBC decline；Improve: heat is moved back, and pharyngalgia subtracts
Gently, tonsillotome reduces, WBC decline；Invalid: not hot to move back, pharyngalgia symptom does not mitigate, antiadoncus, and WBC is constant or rises.Always
Effective percentage=(clinical recovery+effective)/total number of cases × 100%.
Index determining: compare 2 groups of infant overall clinical efficacy rates, resolution of fever time, pharyngalgia extinction time, detection C reaction
Albumen (CRP) is horizontal and white blood cell count(WBC) (WBC) changes.
Statistical procedures: 19.0 statistical software of SPSS processing.Baseline Data case mix ratio chi-square criterion；Measurement data
It is indicated with ± s；Different groups compare to be examined with one-way analysis of variance method；Same group compares before and after treatment with pairing t inspection
It tests；Significance level takes α=0.05.
Each group patient clinical curative effect compares, as a result referring to table 1.
Table 1
According to table 1, observation group's clinical recovery 21, effective 11, effective 5, invalid 4, total effective rate
90.21%；Control group clinical recovery 11, effective 10, there are 7, invalid 11, total effective rate 71.79%.Efficient ratio
Compared with observation group significantly increases (P < 0.05) compared with control group.
Each group patient fever and pharyngalgia recession average time compare, as a result referring to table 2.
Table 2
According to table 2, the observation group patient resolution of fever time, most short is 3h, up to 49h, when average heat generation subsides
Between be 18.45h；Control group patient's resolution of fever time, most short is 9h, up to 62h, and average heat generation regression time is
37.56h.Two groups are compared, and observation group patient is obviously shortened (P < 0.01) the resolution of fever time.
Observation group patient pharyngalgia regression time, most short is 1d, up to 4d, and average pharyngalgia regression time is 2.46d；Control
Group patient's pharyngalgia regression time, most short is 3d, up to 6d, and average pharyngalgia regression time is 4.92d.Two groups are compared, observation group
Patient's pharyngalgia regression time is obviously shortened (P < 0.05).
Each group patient leukocyte count and CRP variation are compared, referring to table 3.
Table 3
According to table 3 can, observation group's patient's quantity of leucocyte variation, observation group and control group patient treatment after leucocyte relatively control
(P < 0.01) is substantially reduced before treatment；Observation group and control group treatment after quantity of leucocyte variation without significant statistical difference (P >
0.05)。
Be substantially reduced before CRP relatively treatment after observation group patient CRP variation, observation group and control group patient treatment (P <
0.01)；CRP changes after comparative observation group and control group treatment, and observation group reduces especially pronounced (P < 0.05).
In conclusion Chinese medicine composition provided by the invention is monarch drug in a prescription, energy by schizonepeta, Rhizoma Et Radix Notopterygii, radix saposhnikoviae interaction altogether
Enough inducing diaphoresis dampness elimination, great burdock achene, the root of Dahurain angelica, campanulaceae, spina gleditsiae and when being classified as ministerial drug, can dampness elimination detumescence, detoxicating and resolving a mass, radices trichosanthis and
Raw Radix Astragali is that adjuvant can be thoroughly evil with righting, enhances resistance of human body, and final realize quickly brings down a fever, reduces swelling, and guarantees drug poison
The low effect of side effect.And by the proportion of above-mentioned restriction drug, it can be further ensured that the curative effect of drug.Above-mentioned Chinese traditional medicine composition
The preparation method of object is simple, and active component content is suitable for guaranteeing the therapeutic effect of medicament.
Embodiments described above is a part of the embodiment of the present invention, instead of all the embodiments.Reality of the invention
The detailed description for applying example is not intended to limit the range of claimed invention, but is merely representative of selected implementation of the invention
Example.Based on the embodiments of the present invention, obtained by those of ordinary skill in the art without making creative efforts
Every other embodiment, shall fall within the protection scope of the present invention.
Claims (10)
1. a kind of for treating the Chinese medicine composition of acute tonsillitis, which is characterized in that in parts by weight comprising schizonepeta 1-
10 parts, 1-10 parts of radix saposhnikoviae, 1-10 parts of Rhizoma Et Radix Notopterygii, 1-10 parts of Radix Angelicae Sinensis, 1-10 parts of the root of Dahurain angelica, 1-9 parts of radices trichosanthis, 1-10 parts of spina gleditsiae, tangerine
Radix Astragali 1-20 parts of 1-12 parts of stalk, 1-10 parts of great burdock achene and life.
2. according to claim 1 for treating the Chinese medicine composition of acute tonsillitis, which is characterized in that with parts by weight
Meter, the Chinese medicine composition includes described schizonepeta 2-8 parts, 2-8 parts of the radix saposhnikoviae, it is Rhizoma Et Radix Notopterygii 2-8 parts described, Radix Angelicae Sinensis 2-8 parts described,
Described root of Dahurain angelica 2-8 parts, it is radices trichosanthis 2-6 parts described, spina gleditsiae 2-8 parts described, campanulaceae 2-10 parts described, great burdock achene 2-8 parts described
With described raw Radix Astragali 5-15 parts.
3. according to claim 1 for treating the Chinese medicine composition of acute tonsillitis, which is characterized in that with parts by weight
Meter, the Chinese medicine composition includes described schizonepeta 4-6 parts, 4-6 parts of the radix saposhnikoviae, it is Rhizoma Et Radix Notopterygii 4-6 parts described, Radix Angelicae Sinensis 4-6 parts described,
Described root of Dahurain angelica 4-6 parts, it is radices trichosanthis 3-5 parts described, spina gleditsiae 4-6 parts described, campanulaceae 4-6 parts described, it is described great burdock achene 4-6 parts and
Described raw Radix Astragali 8-12 parts.
4. according to claim 2 or 3 for treating the Chinese medicine composition of acute tonsillitis, which is characterized in that described
Chinese medicine composition further includes 6-18 parts of gypsum.
5. a kind of described in claim 1 for treating the preparation method of the Chinese medicine composition of acute tonsillitis, feature exists
In, comprising the following steps:
Schizonepeta, radix saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, the root of Dahurain angelica, radices trichosanthis, spina gleditsiae, campanulaceae, great burdock achene and raw Radix Astragali are boiled.
6. preparation method according to claim 5, which is characterized in that the tanning is by the schizonepeta, the radix saposhnikoviae, institute
State Rhizoma Et Radix Notopterygii, the Radix Angelicae Sinensis, the root of Dahurain angelica, the radices trichosanthis, the spina gleditsiae, the campanulaceae, the great burdock achene and the raw Huang
The mixture obtained after stilbene mixing；It then mixes and impregnates according to the ratio of mixture described in every part and the water of 6-12 volume, then
It is decocted.
7. preparation method according to claim 6, which is characterized in that decocting is after mixing the mixture and the water
It obtains substance intense fire and is heated to the 15-17% that boiling then decocts with slow fire the volume for only having original solution to liquor capacity.
8. preparation method according to claim 7, which is characterized in that it is obtained by filtration filtered fluid after decocting with slow fire, and by medicine
Slag is mixed with water according to the water of every part of dregs of a decoction addition 4-6 volume, and infusion is then carried out.
9. preparation method according to claim 8, which is characterized in that the volume for the solution that infusion obtains is original solution volume
10-15%.
10. preparation method according to claim 8, which is characterized in that by solution that infusion obtains and decoct with slow fire to obtain
Solution mixed.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102078574A (en) * | 2009-12-01 | 2011-06-01 | 唐超 | Traditional Chinese medicine pill for treating flu |
| CN102379926A (en) * | 2011-10-18 | 2012-03-21 | 孙克勤 | Traditional Chinese medicine composition for treating viral influenza |
-
2018
- 2018-09-30 CN CN201811156499.XA patent/CN109091533A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102078574A (en) * | 2009-12-01 | 2011-06-01 | 唐超 | Traditional Chinese medicine pill for treating flu |
| CN102379926A (en) * | 2011-10-18 | 2012-03-21 | 孙克勤 | Traditional Chinese medicine composition for treating viral influenza |
Non-Patent Citations (3)
| Title |
|---|
| 冯耀文，等: "驱风解毒汤加味治疗慢性扁桃体炎", 《广西中医药》 * |
| 潘文昭，等: "《日本台湾港澳中医验方选》", 31 October 1989, 广西民族出版社出版 * |
| 陈蓓华，等: ""儿童烂乳蛾辨治体会"", 《浙江中医杂志》 * |
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