CN109091522A - Pulp of dogwood fruit process of preparing technique - Google Patents

Pulp of dogwood fruit process of preparing technique Download PDF

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Publication number
CN109091522A
CN109091522A CN201811140782.3A CN201811140782A CN109091522A CN 109091522 A CN109091522 A CN 109091522A CN 201811140782 A CN201811140782 A CN 201811140782A CN 109091522 A CN109091522 A CN 109091522A
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pulp
dogwood fruit
water
dogwood
crude slice
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马浩明
陈德方
杨立星
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ANHUI HUIZHONGZHOU TRADITIONAL CHINESE MEDICINE DECOCTION PIECES Co Ltd
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ANHUI HUIZHONGZHOU TRADITIONAL CHINESE MEDICINE DECOCTION PIECES Co Ltd
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Priority to CN201811140782.3A priority Critical patent/CN109091522A/en
Publication of CN109091522A publication Critical patent/CN109091522A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/40Cornaceae (Dogwood family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/17Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
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Abstract

The invention discloses a kind of processing procedures of pulp of dogwood fruit medicine materical crude slice, it impregnates comprising water in which rice has been washed, steeping in wine is enucleated, is steamed, salt water frying, liquid medicine impregnates the effect that can enhance pulp of dogwood fruit liver-kidney tonifying, and yellow rice wine can promote the conversion of effective component at separating, and reduces the loss of effective component in subsequent step.Synergistic effect is played with pulp of dogwood fruit after salt water stir-fry.The curative effect of pulp of dogwood fruit controlling nocturnal emission with astringent drugs kidney tonifying can be enhanced.Water in which rice has been washed bubble can mitigate pulp of dogwood fruit pharmacological property, adjust gastrointestinal function, and effective component is promoted to absorb.The effect of content of loganin, morroniside and ursolic acid in pulp of dogwood fruit medicine materical crude slice can be improved with steaming in auxiliary material drug, tannin of degrading, while other drugs ingredient penetrates into pulp of dogwood fruit, and collaboration pulp of dogwood fruit performance is tonified the liver and kidney, astringency inducing.

Description

Pulp of dogwood fruit process of preparing technique
Technical field
The present invention relates to the prepared slices of Chinese crude drugs to process field more particularly to a kind of processing procedure of pulp of dogwood fruit medicine materical crude slice.
Background technique
Chinese medicine contains several chemical components, including toxic, effective component, and the main function of Chinese medicine preparation is that " attenuation increases Effect ", most Chinese medicines can make less toxic by reasonable processing procedure, but since concocting method and auxiliary material are different, with tradition Chinese medicine health product is compared, and material base may be substantially change, and drug effect also can increase drug effect with significant change occurs Purpose, Chinese medicine can reach the therapeutic effect got twice the result with half the effort under appropriate processing procedure.
Theory of traditional Chinese medical science thinks that mountain Zhu English nature and flavor are sour, puckery, tepor, has liver-kidney tonifying, arresting seminal emission sweat, prevent prolapse effect are main to use In treatment soreness of waist and knee joint, dizziness, deafness, impotence, spermatorrhea etc..Clinical use requires stoning, and the stoning reason beginning sees " Thunder God big gun Toast opinion " " nuclear energy spermatorrhoea ".Theoretical foundation of the successive dynasties document mostly in this, as the stoning of mountain Zhu English later.So take a broad view of ancient literature It records, also has the person of holding opposing views to this theory, such as " rope water swallow talks record " is said: " mountain Zhu English energy Psoralen marrow person, takes its core temperature puckery Can secret vital essence, vital essence do not let out, and is so Psoralen marrow, moderns strip meat and the core abandoned, the meaning of big non-ancients." " join in medicine inner feelings West record " speech: " property of its core and meat has closely read report and has sayed core puckery, property also main convergence takes it on the contrary, the used time must remove core Perseverance makes difficult urination, and vertebra is broken to taste it, and fruit has astringent taste person, says or credible ".Tao Hongjing is also said: " mountain Zhu English goes out in all mountains of shortcut, Both did, skin is very thin, when with synkaryon be with " " formulary of peaceful benevolent dispensary " carry " it is all to make, must first smash to pieces to dry and use or only and core Make also to obtain ".Clearly, " doctor ancestor says about " medium cloud " core puckery, spermatorrhea person connect core use ".But these viewpoints fail to generate leading influence, Therefore even to this day, Zhu English in mountain is still enucleated use.After pulp of dogwood fruit wine system is proposed from the Song Dynasty, still applying so far.
Pulp of dogwood fruit modern times concocting method has: " stoning ", " " honey is mixed ", " honey steam " etc., wherein especially with " stoning, " steamed ", " vinegar steaming ", " vinegar is mixed ", " salt system ", the most commonly used, but since various regions medication is accustomed to different, concocting method is also not quite similar.The Liao Dynasty Rather, Chongqing Multipurpose wine mountain cornel, sweet mountain cornel;Jiangsu, Shandong are mostly used " wine steaming " and " steamed ";Hubei, Henan are mostly used " steamed ", " wine Steaming ", " vinegar steaming ";Shanghai is mostly used " steamed ", and Jiangxi, Hunan are mostly used " wine steaming "." People's Republic of China's medicine of miscellaneous editions Allusion quotation ", " national Chinese medicine preparation specification " and each province and city concocted specification mostly " be enucleated ", " wine is stewed ", " wine steaming ", " steamed ", 2005 editions ((Pharmacopoeia of People's Republic of China " it is set to " wine steaming ".
Summary of the invention
The technical problem to be solved in the present invention: the effective component of pulp of dogwood fruit medicine materical crude slice how is improved by processing procedure appropriate Content.
In order to solve the above technical problems, the present invention provides technical solution below:
A kind of processing procedure of pulp of dogwood fruit medicine materical crude slice, comprising the following steps:
(1) the pericarp completely pulp of dogwood fruit fresh goods without wound is selected, is dried after clear water cleaning spare;
(2) pulp of dogwood fruit fresh goods is impregnated 30~60min and is pulled out using water in which rice has been washed and dry, be repeated 2 times;
(3) the pulp of dogwood fruit fresh goods after net system is pressed pulp of dogwood fruit fresh goods: liquid medicine=1:5~10 weight ratios are added liquid medicine and impregnate 24 ~48h is pulled out;
(4) by pulp of dogwood fruit 1.3~1.4bar, 150~200min of high pressure steaming, stoning takes skin and flesh after steaming, and dries;
(5) by every 500g pulp of dogwood fruit with 7~10 grams of salt, add water 100mL to dissolve, be sprinkled upon on pulp of dogwood fruit and mix thoroughly, it is bored profit 30~ 45min sets mild fire in pot and heats, and fried dry is taken out;
(6) pulp of dogwood fruit is steamed into 60~180min with auxiliary material drug again, discards auxiliary material drug, it is obtained by drying;
Wherein, auxiliary material drug is by 15 parts by weight Radix Astragalis, 25 parts by weight Rhizoma Atractylodis Macrocephalaes, 10 parts by weight rhizoma cibotii, 5 parts by weight Rehmannia glutinosas, 8 Parts by weight radix achyranthis bidentatae composition;It is 12%VOL that the liquid medicine, which is in alcoholic strength, and Radix Angelicae Sinensis, fructus lycii, white is added in the yellow rice wine of total reducing sugar 65g/L Chinese herbaceous peony boil cool down after 30min it is obtained.
Preferably, the water in which rice has been washed is glutinous rice: water=1:6~8 weight ratios impregnate the muddy water of elimination glutinous rice after 2~6h.
Preferably, the Radix Angelicae Sinensis, fructus lycii, Radix Paeoniae Alba weight ratio be 1:3:2, be the prepared slices of Chinese crude drugs.
Preferably, the weight ratio of drug and yellow rice wine is 1:3~10 in the liquid medicine.
Preferably, the temperature of the mild fire is 100~140 DEG C, and the weight ratio of the pulp of dogwood fruit and auxiliary material drug is 2~8: 1。
Preferably, the drying condition in the step (4) and (6) is 60~70 DEG C of 1~6h of drying.
It is that the present invention obtains the utility model has the advantages that
(1) liquid medicine impregnates the effect that can enhance pulp of dogwood fruit liver-kidney tonifying, and yellow rice wine can promote the conversion of effective component at separating, Reduce the loss of effective component in subsequent step.
(2) synergistic effect is played with pulp of dogwood fruit after salt water is fried.The curative effect of pulp of dogwood fruit controlling nocturnal emission with astringent drugs kidney tonifying can be enhanced.
(3) water in which rice has been washed bubble can mitigate pulp of dogwood fruit pharmacological property, adjust gastrointestinal function, and effective component is promoted to absorb.
(4) content of loganin, morroniside and ursolic acid in pulp of dogwood fruit medicine materical crude slice can be improved with steaming in auxiliary material drug, tan of degrading The effect of matter, while other drugs ingredient penetrates into pulp of dogwood fruit, collaboration pulp of dogwood fruit performance are tonified the liver and kidney, astringency inducing.
Specific embodiment
Specific embodiments of the present invention will be described in further detail below, to help those skilled in the art couple Inventive concept of the invention, technical solution have more complete, accurate and deep understanding.
The following is an embodiment of the present invention:
Embodiment 1:
Pulp of dogwood fruit medicine materical crude slice is processed as follows:
(1) the pericarp completely pulp of dogwood fruit fresh goods without wound is selected, is dried after clear water cleaning spare;
(2) by glutinous rice: water=1:6 weight ratio filters off glutinous rice after impregnating 2h, and taking upper layer turbid solution is water in which rice has been washed.
(3) pulp of dogwood fruit fresh goods is impregnated 30min and is pulled out using water in which rice has been washed and dry, be repeated 2 times;
It (4) is by weight that 1:3:2 nominal takes 1kg by prepared slices of Chinese crude drugs Radix Angelicae Sinensis, fructus lycii, Radix Paeoniae Alba, 3kg alcoholic strength, which is added, is 12%VOL, the yellow rice wine of total reducing sugar 65g/L boil that cool down obtained liquid medicine after 30min spare;
(5) by the pulp of dogwood fruit fresh goods after net system by pulp of dogwood fruit fresh goods: liquid medicine=1:5 weight ratio is added liquid medicine immersion and fishes out for 24 hours Out;
(6) by pulp of dogwood fruit 1.3bar high pressure steaming 150min, stoning takes skin and flesh, 60 DEG C of drying 1h after steaming;
(7) added water 100mL to dissolve with 7 grams of salt by every 500g pulp of dogwood fruit, be sprinkled upon on pulp of dogwood fruit and mix thoroughly, bored profit 30min is set (100~140 DEG C) of mild fire heating in pot, fried dry are taken out;
(8) 15kg Radix Astragali, 25kg Rhizoma Atractylodis Macrocephalae, 10kg rhizoma cibotii, 5kg Rehmannia glutinosa, 8kg radix achyranthis bidentatae are weighed, chopping is mixed thoroughly rear spare;
(9) addition 1kg auxiliary material drug is mixed thoroughly and steams 60min in every 2kg pulp of dogwood fruit, discards auxiliary material drug, 60 DEG C of drying 6h To obtain the final product;
Embodiment 2:
Pulp of dogwood fruit medicine materical crude slice is processed as follows:
(1) the pericarp completely pulp of dogwood fruit fresh goods without wound is selected, is dried after clear water cleaning spare;
(2) by glutinous rice: water=1:8 weight ratio filters off glutinous rice after impregnating 6h, and taking upper layer turbid solution is water in which rice has been washed.
(3) pulp of dogwood fruit fresh goods is impregnated 60min and is pulled out using water in which rice has been washed and dry, be repeated 2 times;
It (4) is by weight that 1:3:2 nominal takes 1kg by prepared slices of Chinese crude drugs Radix Angelicae Sinensis, fructus lycii, Radix Paeoniae Alba, 10kg alcoholic strength, which is added, is 12%VOL, the yellow rice wine of total reducing sugar 65g/L boil that cool down obtained liquid medicine after 30min spare;
(5) the pulp of dogwood fruit fresh goods after net system is pressed pulp of dogwood fruit fresh goods: liquid medicine=1:10 weight ratio is added liquid medicine and impregnates 48h fishing Out;
(6) by pulp of dogwood fruit 1.4bar high pressure steaming 200min, stoning takes skin and flesh, 70 DEG C of drying 6h after steaming;
(7) added water 100mL to dissolve with 10 grams of salt by every 500g pulp of dogwood fruit, be sprinkled upon on pulp of dogwood fruit and mixed thoroughly, bored profit 45min, (100~140 DEG C) of mild fire in pot heating are set, fried dry is taken out;
(8) 15kg Radix Astragali, 25kg Rhizoma Atractylodis Macrocephalae, 10kg rhizoma cibotii, 5kg Rehmannia glutinosa, 8kg radix achyranthis bidentatae are weighed, chopping is mixed thoroughly rear spare;
(9) addition 1kg auxiliary material drug is mixed thoroughly and steams 180min in every 8kg pulp of dogwood fruit, discards auxiliary material drug, 70 DEG C of drying 1 To obtain the final product;
Embodiment 3:
Pulp of dogwood fruit medicine materical crude slice is processed as follows:
(1) the pericarp completely pulp of dogwood fruit fresh goods without wound is selected, is dried after clear water cleaning spare;
(2) by glutinous rice: water=1:7 weight ratio filters off glutinous rice after impregnating 4h, and taking upper layer turbid solution is water in which rice has been washed.
(3) pulp of dogwood fruit fresh goods is impregnated 45min and is pulled out using water in which rice has been washed and dry, be repeated 2 times;
It (4) is by weight that 1:3:2 nominal takes 1kg by prepared slices of Chinese crude drugs Radix Angelicae Sinensis, fructus lycii, Radix Paeoniae Alba, 6kg alcoholic strength, which is added, is 12%VOL, the yellow rice wine of total reducing sugar 65g/L boil that cool down obtained liquid medicine after 30min spare;
(5) the pulp of dogwood fruit fresh goods after net system is pressed pulp of dogwood fruit fresh goods: liquid medicine=1:8 weight ratio is added liquid medicine and impregnates 36h fishing Out;
(6) by pulp of dogwood fruit 1.5bar high pressure steaming 180min, stoning takes skin and flesh, 65 DEG C of drying 3h after steaming;
(7) added water 100mL to dissolve with 8.5 grams of salt by every 500g pulp of dogwood fruit, be sprinkled upon on pulp of dogwood fruit and mixed thoroughly, bored profit 40min, (100~140 DEG C) of mild fire in pot heating are set, fried dry is taken out;
(8) 15kg Radix Astragali, 25kg Rhizoma Atractylodis Macrocephalae, 10kg rhizoma cibotii, 5kg Rehmannia glutinosa, 8kg radix achyranthis bidentatae are weighed, chopping is mixed thoroughly rear spare;
(9) addition 1kg auxiliary material drug is mixed thoroughly and steams 120min in every 5kg pulp of dogwood fruit, discards auxiliary material drug, 65 DEG C of drying 3h To obtain the final product;
According to the pulp of dogwood fruit quality standard detecting method and index recorded in 2005 editions Chinese Pharmacopoeias to being made in embodiment 1-3 Standby pulp of dogwood fruit medicine materical crude slice and common wine FRUCTUS CORNI PREPARATA medicine materical crude slice is detected, as a result as follows:
The content of loganin, ursolic acid, morroniside and total tannin in 1 pulp of dogwood fruit of table
Sample Strychnos nux-vomica cellulose content (%) Ursolic acid content (%) Morroniside content (%) Total tannin (%)
Embodiment 1 5.65 0.96 1.69 2.07
Embodiment 2 5.69 1.36 1.49 2.59
Embodiment 3 5.54 1.27 1.77 2.29
Wine FRUCTUS CORNI PREPARATA 3.89 0.66 1.11 3.02
Pulp of dogwood fruit pericarp health product 6.21 1.98 2.01 4.25
The loss of effective component is less during the present invention processes pulp of dogwood fruit as the result is shown for table 1, embodiment 1-3 preparation Active constituent content in pulp of dogwood fruit medicine materical crude slice is apparently higher than wine FRUCTUS CORNI PREPARATA medicine materical crude slice, and is much higher than National Pharmacopeia standard.Tan simultaneously The content of matter declines, caused by tannin hydrolysis water-soluble during steaming or being lost, and tannin be it is non-it is medicinal at Point, in a disguised form improve the content of effective component.
Using document: the small warbler of king, Hu Guoliang, Zhang Caiying wait liver protection shield spleen liquid to damage carbon tetrachloride induced mice Acute Hepatic Protective effect [J] traditional Chinese veterinary medicine magazine of wound, 2006 (2): protection of the method measurement present invention to hepatic injury in 10-11. Effect.
The tested medical fluid preparation of embodiment 1-3: blank control group and model group give physiological saline, embodiment 1-3 component Pure water is not added by the weight ratio of 1:10 in different pulp of dogwood fruit medicine materical crude slice, 1h is decocted, takes filtrate as medical fluid after filtering.
As a result as follows:
The activity (IU/L) of glutamic-oxalacetic transaminease and glutamic-pyruvic transaminase in 2 blood plasma of table
Experimental result shows that apparent ballooning degeneration, steatosis, blood is presented in carbon tetrachloride model group's mouse liver Clear glutamic-pyruvic transaminase (ALT), glutamic-oxalacetic transaminease (AST) are significant to be increased, and shows that stem cell seriously damages, embodiment 1-3 Close to normally, Serum ALT, AST are substantially reduced medication therapy groups mouse liver appearance color, close to normal level, illustrate this hair The pulp of dogwood fruit medicine materical crude slice of bright preparation can effectively protect hepatic injury.
In conclusion liquid medicine, which impregnates, can enhance the effect of pulp of dogwood fruit liver-kidney tonifying, yellow rice wine can promote effective component at separating Conversion, reduce subsequent step in effective component loss.Synergistic effect is played with pulp of dogwood fruit after salt water stir-fry.Mountain cornel can be enhanced The curative effect of meat controlling nocturnal emission with astringent drugs kidney tonifying.Water in which rice has been washed bubble can mitigate pulp of dogwood fruit pharmacological property, adjust gastrointestinal function, and effective component is promoted to absorb.It is auxiliary Expect that with steaming, the content of loganin, morroniside and ursolic acid in pulp of dogwood fruit medicine materical crude slice is can be improved in drug, tannin of degrading, while its other medicine The effect of object ingredient penetrates into pulp of dogwood fruit, and collaboration pulp of dogwood fruit performance is tonified the liver and kidney, astringency inducing.
The present invention is exemplarily described above, it is clear that present invention specific implementation is not subject to the restrictions described above, As long as using the improvement for the various unsubstantialities that the inventive concept and technical scheme of the present invention carry out, or not improved by this The conception and technical scheme of invention directly apply to other occasions, within the scope of the present invention.Guarantor of the invention Shield range should be determined by the scope of protection defined in the claims.

Claims (6)

1. a kind of processing procedure of pulp of dogwood fruit medicine materical crude slice, which comprises the following steps:
(1) the pericarp completely pulp of dogwood fruit fresh goods without wound is selected, is dried after clear water cleaning spare;
(2) pulp of dogwood fruit fresh goods is impregnated 30~60min and is pulled out using water in which rice has been washed and dry, be repeated 2 times;
(3) by the pulp of dogwood fruit fresh goods after net system by pulp of dogwood fruit fresh goods: liquid medicine=1:5~10 weight ratios addition liquid medicine immersion 24~ 48h is pulled out;
(4) by pulp of dogwood fruit 1.3~1.4bar, 150~200min of high pressure steaming, stoning takes skin and flesh after steaming, and dries;
(5) by every 500g pulp of dogwood fruit with 7~10 grams of salt, add water 100mL to dissolve, be sprinkled upon on pulp of dogwood fruit and mix thoroughly, it is bored profit 30~ 45min sets mild fire in pot and heats, and fried dry is taken out;
(6) pulp of dogwood fruit is steamed into 60~180min with auxiliary material drug again, discards auxiliary material drug, it is obtained by drying;
Wherein, auxiliary material drug is by 15 parts by weight Radix Astragalis, 25 parts by weight Rhizoma Atractylodis Macrocephalaes, 10 parts by weight rhizoma cibotii, 5 parts by weight Rehmannia glutinosas, 8 weight Part radix achyranthis bidentatae composition;It is 12%VOL that the liquid medicine, which is in alcoholic strength, and Radix Angelicae Sinensis, fructus lycii, Radix Paeoniae Alba is added in the yellow rice wine of total reducing sugar 65g/L and boils It is cooled down after boiling 30min obtained.
2. a kind of processing procedure of pulp of dogwood fruit medicine materical crude slice according to claim 1, it is characterised in that: the water in which rice has been washed is glutinous Rice: water=1:6~8 weight ratios impregnate the muddy water of elimination glutinous rice after 2~6h.
3. a kind of processing procedure of pulp of dogwood fruit medicine materical crude slice according to claim 1, it is characterised in that: the Radix Angelicae Sinensis, fructus lycii, white The weight ratio of Chinese herbaceous peony is 1:3:2, is the prepared slices of Chinese crude drugs.
4. a kind of processing procedure of pulp of dogwood fruit medicine materical crude slice according to claim 1, it is characterised in that: in the liquid medicine drug with The weight ratio of yellow rice wine is 1:3~10.
5. a kind of processing procedure of pulp of dogwood fruit medicine materical crude slice according to claim 1, it is characterised in that: the temperature of the mild fire is 100~140 DEG C, the weight ratio of the pulp of dogwood fruit and auxiliary material drug is 2~8:1.
6. a kind of processing procedure of pulp of dogwood fruit medicine materical crude slice according to claim 1, it is characterised in that: the step (4) and (6) In drying condition be 60~70 DEG C of 1~6h of drying.
CN201811140782.3A 2018-09-28 2018-09-28 Pulp of dogwood fruit process of preparing technique Pending CN109091522A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114796299A (en) * 2022-04-22 2022-07-29 河北万邦复临药业有限公司 Method for processing cornus officinalis

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Publication number Priority date Publication date Assignee Title
CN104940271A (en) * 2015-06-19 2015-09-30 亳州市永刚饮片厂有限公司 Manufacture method of cornus officinalis decoction pieces

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