CN109077982A - A kind of improvement infant skin barrier the effect of property lotion - Google Patents

A kind of improvement infant skin barrier the effect of property lotion Download PDF

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Publication number
CN109077982A
CN109077982A CN201811297063.2A CN201811297063A CN109077982A CN 109077982 A CN109077982 A CN 109077982A CN 201811297063 A CN201811297063 A CN 201811297063A CN 109077982 A CN109077982 A CN 109077982A
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China
Prior art keywords
raw material
effect
skin barrier
triethanolamine
skin
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Pending
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CN201811297063.2A
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Chinese (zh)
Inventor
沈华忠
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Guangzhou Huacheng Health Industry Co Ltd
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Guangzhou Huacheng Health Industry Co Ltd
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Priority to CN201811297063.2A priority Critical patent/CN109077982A/en
Publication of CN109077982A publication Critical patent/CN109077982A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/927Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of insects, e.g. shellac
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Cosmetics (AREA)

Abstract

The present invention provides a kind of improvement infant skin barrier the effect of property lotion, it is made of following raw material: tuckahoe extracts, borax, lanolin, Radix Paeoniae Alba, olive oil, lophatherum gracile, oat bran, chrysanthemum, triethanolamine, ethyl alcohol, acrylic acid, magnesium carbonate, beeswax, lignosulfonate, mulberry leaf, deionized water, compared with prior art, the present invention is with following the utility model has the advantages that having no adverse effects to human body, eliminate pigment excess accumulation in the tissue, promote skin cell metabolism, so that skin is moistened bright and clean, high resilience, is suitble to the tender skin of infant.

Description

A kind of improvement infant skin barrier the effect of property lotion
Technical field
The present invention is a kind of improvement infant skin barrier the effect of property lotion, belongs to emulsion technology field.
Background technique
Skin is located at human body surface, is the first line of defence of human body, has highly important barrier function.With human body other Organ is the same, and the skin development of infancy is not perfect.Especially there are great differences for infant's skin texture and adult, baby The cutaneous sensibility in child's period will be much higher than adult, be highly prone to the influence of external environment variation.The burning sun of summer and winter The cold wind in season, southern warm and humid and northern dry and cold and increasingly severe environmental problem: haze, acid rain, sand and dust etc., all The discomfort of infant's skin can be made to increase, so infant needs preferably to protect and enhance skin barrier function.
Currently, the fields such as cosmetics and medicine generally use percutaneous moisture loss as the standard for measuring skin barrier function Test method.TEWL value is directly related to the permeability of cuticula and the water of skin and effect, and TEWL value is higher, shows through skin The moisture lost is more, and the screen effect of cuticula is more bad.Infant develops not perfect, TEWL due to the natural barrier of skin Value can more adult height.Correlative study data show that the dehydration degree of 3-6 months babies is most fast, are 4 times of adult;7-12 Baby's dehydration degree of the moon is 3 times of adult.If nursing is improper, infant's dry skin will lead to, the scales of skin that peel off increases, and dry Skin increase the friction between external environment, be easy further to cause inflammation and redness, baby will brothers grab, sleep Uneasiness, this will undoubtedly hinder growth and development.So the main purpose of infant's skin nursing is the complete of maintenance epidermal barrier Property, dispel, prevent, lowering the issuable pathogenic factor of ambient enviroment, protect the skin of the delicate sensitivity of infant, enhance its skin Skin itself resists the dysgenic ability of external environment.
Mainly based on isolation, auxiliary is not changed really infant skin care product with moisturizing, moist effect currently on the market Barrier effect of kind skin itself, can not also repair impaired skin barrier.
Summary of the invention
In view of the deficienciess of the prior art, it is an object of the present invention to provide a kind of improvement infant skin barrier the effect of property Lotion, to solve the problems mentioned in the above background technology.
To achieve the goals above, the present invention is to realize by the following technical solutions: a kind of improvement infant's skin The effect of barrier property lotion is made of following raw material: tuckahoe extracts, borax, lanolin, Radix Paeoniae Alba, olive oil, lophatherum gracile, swallow Wheat bran skin, chrysanthemum, triethanolamine, ethyl alcohol, acrylic acid, magnesium carbonate, beeswax, lignosulfonate, mulberry leaf, deionized water.
Further, the summer, two season of autumn excavation ranunculaceae plant Chinese herbaceous peony dry root, clean, remove end to end and radicula, set boiling After being boiled in water, boiled again after removing crust or peeling, dry, be then placed in pulverizer and crush, cross 50 meshes, sieve in raw material Radix Paeoniae Alba.
Further, Poria cocos is taken, is impregnated, is cleaned, is slightly steamed after profit, prune crust in time, cutting is blocking or cuts sheet, shines It is dry, method extraction is extracted with water, obtains the tuckahoe extracts in raw material.
Further, pretreated boron magnesium ore powder is mixed with sodium hydroxide solution, temperature-pressure decomposes to obtain metaboric acid Sodium solution, then through carbonization treatment, obtain the borax in raw material.
Further, the olive oil in raw material is a kind of Extra Virgin, olive oleic acid in the olive oil in raw material Degree is lower than 0.8%.
Further, take tip of a leaf matter hard, 0.5~1 millimeter long, brown, back has rough hair, and blade lanceolar is 6~20 lis long Rice, it is 1.5~2.5 centimetres wide, have the lophatherum gracile of transverse vein, natural air drying is put into pulverizer and crushes, and sieves with 100 mesh sieve, and sieves to obtain raw material In lophatherum gracile.
Further, ethylene oxide, ammonium hydroxide are sent into reactor, at 30-40 DEG C of reaction temperature, reaction pressure 70.9- It under 304kPa, carries out condensation reaction and generates one, two, triethanolamine mixed liquor, at 90-120 DEG C after dehydration concentration, be sent into three A vacuum rectification tower is evaporated under reduced pressure, by different boiling intercept fraction, then monoethanolamine, diethanol amine and triethanolamine at Product increase ethylene oxide ratio, while being removed after the reaction to triethanolamine finished product product with steam distillation during the reaction Ethanol amine is removed, sodium hydroxide, which is added, is precipitated triethanolamine at alkali metal salt, neutralizes after separation, then carry out being evaporated under reduced pressure to original Triethanolamine in material.
Beneficial effects of the present invention: a kind of improvement infant skin barrier the effect of property lotion of the invention, to human body without Pigment excess accumulation in the tissue is eliminated in adverse effect, promotes skin cell metabolism, make skin moisten it is bright and clean, rich in bullet Property, it is suitble to the tender skin of infant.
Specific embodiment
To be easy to understand the technical means, the creative features, the aims and the efficiencies achieved by the present invention, below with reference to Specific embodiment, the present invention is further explained.
The present invention provides a kind of technical solution: a kind of improvement infant skin barrier the effect of property lotion, by following raw material It constitutes: tuckahoe extracts, borax, lanolin, Radix Paeoniae Alba, olive oil, lophatherum gracile, oat bran, chrysanthemum, triethanolamine, ethyl alcohol, third Olefin(e) acid, magnesium carbonate, beeswax, lignosulfonate, mulberry leaf, deionized water.
Summer, two season of autumn excavation ranunculaceae plant Chinese herbaceous peony dry root, clean, remove end to end and radicula, set after being boiled in boiling water, It is boiled again after removing crust or peeling, dries, be then placed in pulverizer and crush, cross 50 meshes, sieve to obtain Radix Paeoniae Alba in raw material.
Poria cocos is taken, is impregnated, is cleaned, is slightly steamed after profit, prune crust in time, cutting is blocking or cuts sheet, dries, is extracted with water Method is extracted, and the tuckahoe extracts in raw material are obtained.
Pretreated boron magnesium ore powder is mixed with sodium hydroxide solution, temperature-pressure decomposes to obtain sodium metaborate solution, then Through carbonization treatment, the borax in raw material is obtained.
Olive oil in raw material is a kind of Extra Virgin, and olive oil acidity is lower than in the olive oil in raw material 0.8%。
Take tip of a leaf matter hard, 0.5~1 millimeter long, brown, back has rough hair, and blade lanceolar is 6~20 centimetres long, wide by 1.5~ 2.5 centimetres, has the lophatherum gracile of transverse vein, natural air drying is put into pulverizer and crushes, and sieves with 100 mesh sieve, and sieves to obtain henon bamboo in raw material Leaf.
Ethylene oxide, ammonium hydroxide are sent into reactor, under 30-40 DEG C of reaction temperature, reaction pressure 70.9-304kPa, It carries out condensation reaction and generates one, two, triethanolamine mixed liquor, at 90-120 DEG C after dehydration concentration, be sent into three decompression essences It evaporates tower to be evaporated under reduced pressure, intercepts fraction by different boiling, then monoethanolamine, diethanol amine and triethanolamine finished product are obtained, anti- During answering, ethylene oxide ratio is increased, while ethyl alcohol is removed to triethanolamine finished product product steam distillation after the reaction Amine, sodium hydroxide, which is added, is precipitated triethanolamine at alkali metal salt, neutralizes after separation, then be evaporated under reduced pressure in raw material Triethanolamine.
As an embodiment of the present invention: a kind of improvement infant skin barrier the effect of property lotion of the invention is right Human body has no adverse effects, and eliminates pigment excess accumulation in the tissue, promotes skin cell metabolism, make skin moisten it is bright and clean, High resilience is suitble to the tender skin of infant.
The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention, for this field skill For art personnel, it is clear that invention is not limited to the details of the above exemplary embodiments, and without departing substantially from spirit of the invention or In the case where essential characteristic, the present invention can be realized in other specific forms.Therefore, in all respects, should all incite somebody to action Embodiment regards exemplary as, and is non-limiting, the scope of the present invention by appended claims rather than on state Bright restriction, it is intended that including all changes that fall within the meaning and scope of the equivalent elements of the claims in the present invention It is interior.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art The other embodiments being understood that.

Claims (7)

1. a kind of improvement infant skin barrier the effect of property lotion, it is characterised in that: be made of following raw material: Poria cocos extracts Object, borax, lanolin, Radix Paeoniae Alba, olive oil, lophatherum gracile, oat bran, chrysanthemum, triethanolamine, ethyl alcohol, acrylic acid, magnesium carbonate, Beeswax, lignosulfonate, mulberry leaf, deionized water.
2. a kind of improvement infant skin barrier the effect of property lotion according to claim 1, it is characterised in that: summer, autumn Two seasons excavated the dry root of ranunculaceae plant Chinese herbaceous peony, cleaned, and removed end to end and radicula, set after boiling in boiling water, removed crust or went It boils, dries again after skin, be then placed in pulverizer and crush, cross 50 meshes, sieve to obtain Radix Paeoniae Alba in raw material.
3. a kind of improvement infant skin barrier the effect of property lotion according to claim 1, it is characterised in that: take Fu Siberian cocklebur is impregnated, and cleans, slightly steams after profit, prune crust in time, and cutting is blocking or cuts sheet, dries, and method extraction is extracted with water, obtains Tuckahoe extracts in raw material.
4. a kind of improvement infant skin barrier the effect of property lotion according to claim 1, it is characterised in that: will locate in advance Boron magnesium ore powder after reason is mixed with sodium hydroxide solution, and temperature-pressure decomposes to obtain sodium metaborate solution, then through carbonization treatment, obtains Borax in raw material.
5. a kind of improvement infant skin barrier the effect of property lotion according to claim 1, it is characterised in that: in raw material Olive oil be a kind of Extra Virgin, olive oil acidity is lower than 0.8% in the olive oil in raw material.
6. a kind of improvement infant skin barrier the effect of property lotion according to claim 1, it is characterised in that: take the tip of a leaf Matter is hard, 0.5~1 millimeter long, brown, and back has rough hair, and blade lanceolar is 6~20 centimetres long, 1.5~2.5 centimetres wide, has transverse vein Lophatherum gracile, natural air drying is put into pulverizer and crushes, sieve with 100 mesh sieve, and sieves to obtain lophatherum gracile in raw material.
7. a kind of improvement infant skin barrier the effect of property lotion according to claim 1, it is characterised in that: by epoxy Ethane, ammonium hydroxide are sent into reactor, and under 30-40 DEG C of reaction temperature, reaction pressure 70.9-304kPa, it is raw to carry out condensation reaction Cheng Yi, two, triethanolamine mixed liquor are sent into three vacuum rectification towers and carry out decompression steaming at 90-120 DEG C after dehydration concentration It evaporates, intercepts fraction by different boiling, then obtain monoethanolamine, diethanol amine and triethanolamine finished product, during the reaction, enlarged link Oxidative ethane ratio, while ethanol amine is removed to triethanolamine finished product product steam distillation after the reaction, sodium hydroxide is added Triethanolamine is precipitated at alkali metal salt, is neutralized after separation, then carries out the triethanolamine being evaporated under reduced pressure in raw material.
CN201811297063.2A 2018-11-01 2018-11-01 A kind of improvement infant skin barrier the effect of property lotion Pending CN109077982A (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101756836A (en) * 2008-11-25 2010-06-30 夏栋 Lithospermum cream for men
CN102429847A (en) * 2011-12-24 2012-05-02 大连创达技术交易市场有限公司 Pure natural sunscreen cream special for pregnant women
CN102836114A (en) * 2012-09-24 2012-12-26 南京正亮医药科技有限公司 Skin-moistening emulsion
CN105997625A (en) * 2016-05-19 2016-10-12 重庆苗秀生物科技股份有限公司 Moistening cream for daily skin and mucosa care of children and application of moistening scream
CN106176466A (en) * 2016-08-30 2016-12-07 思拓科(上海)生物科技股份有限公司 Child's facial cream and preparation method thereof
CN107412087A (en) * 2017-04-14 2017-12-01 天津盛世永业科技发展有限公司 A kind of plant composition and its emulsion for improving infant's skin barrier effect
CN107412089A (en) * 2017-04-14 2017-12-01 天津盛世永业科技发展有限公司 A kind of care agent and its preparation technology for improving infant's skin barrier effect

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101756836A (en) * 2008-11-25 2010-06-30 夏栋 Lithospermum cream for men
CN102429847A (en) * 2011-12-24 2012-05-02 大连创达技术交易市场有限公司 Pure natural sunscreen cream special for pregnant women
CN102836114A (en) * 2012-09-24 2012-12-26 南京正亮医药科技有限公司 Skin-moistening emulsion
CN105997625A (en) * 2016-05-19 2016-10-12 重庆苗秀生物科技股份有限公司 Moistening cream for daily skin and mucosa care of children and application of moistening scream
CN106176466A (en) * 2016-08-30 2016-12-07 思拓科(上海)生物科技股份有限公司 Child's facial cream and preparation method thereof
CN107412087A (en) * 2017-04-14 2017-12-01 天津盛世永业科技发展有限公司 A kind of plant composition and its emulsion for improving infant's skin barrier effect
CN107412089A (en) * 2017-04-14 2017-12-01 天津盛世永业科技发展有限公司 A kind of care agent and its preparation technology for improving infant's skin barrier effect

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Application publication date: 20181225