CN109073552A - Sample detection means - Google Patents

Sample detection means Download PDF

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Publication number
CN109073552A
CN109073552A CN201680084836.1A CN201680084836A CN109073552A CN 109073552 A CN109073552 A CN 109073552A CN 201680084836 A CN201680084836 A CN 201680084836A CN 109073552 A CN109073552 A CN 109073552A
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CN
China
Prior art keywords
sample
lens section
plane
axis
detection means
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201680084836.1A
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Chinese (zh)
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CN109073552B (en
Inventor
金嶂柱
文畅基
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seoul National University Industry Foundation
SNU R&DB Foundation
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Seoul National University Industry Foundation
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Publication of CN109073552A publication Critical patent/CN109073552A/en
Application granted granted Critical
Publication of CN109073552B publication Critical patent/CN109073552B/en
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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/0303Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N3/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N3/02Details
    • G01N3/04Chucks
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B5/00Optical elements other than lenses
    • G02B5/02Diffusing elements; Afocal elements

Abstract

The present invention relates to sample detection means, relate more specifically to sample and is in close contact lens section, the exciting light generated by sample is by lens section by extensive diffusive, the exciting light spread selectively can be captured and be analyzed according to special angle, to which the dispensing of sample is simple, sample detection also extremely simple and reliable sample detection means.

Description

Sample detection means
Technical field
The present invention relates to sample detection means, relate more specifically to sample and are in close contact lens section, give sample irradiation light, by The exciting light that sample generates, by extensive diffusive, the exciting light spread is selectively captured according to special angle by lens section And analyze, so that the dispensing of sample is simple, sample detection also extremely simple and reliable sample detection means.
Background technique
When detection includes the sample of scheduled sample survey, film, microorganism etc., using scheduled light source to sample irradiation The light such as ultraviolet light (UV light) then analyze the intensity or distribution of exciting light that the sample is excited and generates, to carry out sample Product examine is surveyed.
This sample detection means and method are that the irradiation light of the light source need to accurately be incident on scheduled analysis sample On.If unnecessary exterior light, reflected light, the non-light source, that is, other irradiation lights are incident on analysis sample, or it is irradiated to When the area of the light of sample is too big, then the accuracy in detection of sample can be substantially reduced.But also need one kind in being measured Irradiation light can be stopped to be leaked to device that is external and injuring human body.
Also, the exciting light generated on sample passes through the lens being arranged and is spread apart, therefore one kind is also needed to be easy to catch Obtain the device of the exciting light of the diffusion analyzed.
Summary of the invention
Technical problem
The object of the present invention is to provide a kind of samples can be in close contact lens section, is led to by the exciting light that sample generates Lens section is crossed by extensive diffusive, the exciting light spread is selectively captured and analyzed according to special angle, thus sample Launch simple, the detection of sample is very simple and reliable sample detection means.
Technical solution
In order to realize the purpose, sample detection means of the invention include: power part, provide rotary force;Turntable, It is with predetermined area and is connected to the power part, flat in XY centered on along the predetermined Pivot axle that Z-direction extends It is rotatably constituted on face;Lens section is set on the turntable, can be with the rotation centered on the Pivot axle Turntable is rotatably constituted together, is placed in the side on the turntable;Specimen holder is placed on the turntable, with described It can rotatably constitute, and be placed in relative to the Pivot axle described together with the turntable centered on Pivot axle The opposite side of lens section is rotatably connected at the turntable;And
Angle fixed part is placed on the turntable, and is configured to that the angle of the specimen holder can be fixed;It is described Mirror portion has the plane of incidence that the side facing with the specimen holder is formed in predetermined plane, and the specimen holder includes: rotation axis, It extends along the y axis and is connected to the turntable;Rotor, one end are connected to the rotation by the rotation axis Platform, and can be rotatably coupled in XZ plane centered on the rotation axis;And light source portion, it is placed in the rotor It is interior.The rotor has the loading surface that can place predetermined sample with the facing position of the lens section, with described Rotor is rotated centered on the rotation axis, and the angle between the loading surface and the plane of incidence can change.Institute It states the position of the fixed specimen holder of angle fixed part and the angle between the loading surface and the plane of incidence is made to keep predetermined Angle.It is raw by the light source portion in the state that angle between the loading surface and the plane of incidence is fixed into predetermined angular At irradiation light be irradiated to the sample when, the exciting light that the sample is excited and generates is projected by the border portion.
Preferably, the lens section along Z-direction have predetermined thickness, the lens section along the x axis before Uprightly be formed with the plane of incidence, the lens section along the x axis behind be formed with and be formed as the half of semicircle curved surface Round lens.
Preferably, the rotor includes: the cant beam that one end is connected to the rotation axis;It is connected to the cant beam The other end, and in order to which the light source portion is installed on internal and has the shell in space in inside.The loading surface is arranged described The position facing with the lens section at the rear along the x axis of shell.
Preferably, when the cant beam is upright, the angle between the loading surface and the plane of incidence becomes 0 °, is placed in The plane of incidence of sample and the lens section on the loading surface is closely contacted with each other.
Preferably, the cant beam and the shell are bent with mutually having predetermined angle, and the light source portion is described In the state that cant beam is upright by light diagonally be irradiated to the sample in downward direction.
Preferably, the rotor includes making the securing fixed device of the sample position on the loading surface, described solid Determine the top that device is placed in the loading surface, and includes: the small axis of rotation extended along the y axis;In being with the small axis of the rotation The rotation fixed pin that the heart rotates in XZ plane.When placing the sample on the loading surface, the rotation fixed pin construction The position of the fixed sample at a part for the upper end for covering the sample.
Preferably, the angle fixed part is located at the front of the specimen holder in the X-axis direction and includes: to be fixed on institute State the base clamp on turntable;And it is rotationally constituted and the position of the fixed specimen holder relative to the base clamp Rotary clamp.
Preferably, the rotary clamp is placed in the two sides of the base station in the Y-axis direction, with the branch extended along the x axis It is rotated centered on support axis, in the state that the specimen holder is upright, the rotary clamp is turned upwards centered on the support shaft When dynamic, the rotary clamp support the specimen holder along the x axis before and the position of the fixed specimen holder.
Preferably, the turntable includes: the base station for being connected to the power part;Cover the top above the lens section Lid;And be set to the two sides of the specimen holder in the Y-axis direction and stand upright on the base station, connect the base station and described Upper cap, and there is the interconnecting piece to connect below with the plane of incidence of the lens section.
Preferably, the base station has circular shape, and the upper surface of described base station is divided into the mutually different semi-circular shape of height Lens face and basal plane, the height of the lens face lower than the basal plane height and between the lens face and the basal plane Cascaded surface is formed, the lens face is equipped with the lens section, and the basal plane is equipped with illumination part and angle fixed part.
Preferably, the plane of incidence of the cascaded surface and the lens section is mutually located at the same face and constitutes one side.
Preferably, fluid slot is formed on the basal plane, is formed in the outside of the angle fixed part, had scheduled Depth, inside are filled with scheduled liquid.
Preferably, the sample has transmissive portions, has the predetermined area for placing scheduled test sample, and by having The material of translucency is constituted, and the refractive index of the transmissive portions is identical as the refractive index of the lens section.
Preferably, the sample includes liquid solvent, and the liquid solvent is painted on the detection being placed on the transmissive portions On sample, it is in close contact the plane of incidence of the test sample and transmissive portions and the lens section, the folding of the liquid solvent It is identical as the refractive index of the lens section to penetrate rate.
Preferably, further includes: light is placed in the rear of the lens section, and in the X-axis direction by portion can make The light for crossing the lens section has scheduled slit by way of;And analytical equipment, it receives and portion is passed through by the light Light and analyze the light.
Preferably, further include the adjustable turntable rotation angle and initial angle angle adjustment.
Beneficial effect
Sample detection means according to the present invention, the beneficial effect is that, the detection of sample can be very simple and reliable Ground carries out.Especially sample can be in close contact lens section, and the exciting light generated on sample, by extensive diffusive, is incited somebody to action by lens section The exciting light spread is selectively captured and is analyzed according to special angle, to accurately be analyzed.
Device is integrally covered by shell, and the irradiation light and exciting light irradiated from light source portion will not be leaked to outside, thus anti- Only user is exposed in harmful light.
Detailed description of the invention
Fig. 1 is the schematic diagram for showing the shape of sample detection means of one embodiment of the invention;
Fig. 2 is the schematic diagram of the door open state on the shell for the sample detection means for showing one embodiment of the invention;
Fig. 3 is the schematic diagram for showing the interior arrangement structure of sample detection means of the invention;
Fig. 4 is the schematic diagram that the interior arrangement of Fig. 3 is checked above Z-direction;
Fig. 5 is to check the schematic diagram of the interior arrangement of Fig. 3 in the side of Y direction;
Fig. 6 is the schematic diagram that the interior arrangement of Fig. 2 is checked in front of X-direction;
Fig. 7 is to show that sample is loaded onto specimen holder when the specimen holder of sample detection means of the invention is open mode When state schematic diagram;
Fig. 8 to Figure 10 is the schematic diagram for showing the operation of sample detection means of the invention;
Figure 11 is the schematic diagram for showing the sample detection mode of one embodiment of the invention;
Figure 12 a and Figure 12 b are the schematic diagrames for showing an example of testing result.
Specific embodiment
Include: power part according to the sample detection means of the invention of an embodiment, rotary force is provided;Turntable, With predetermined area and be connected to the power part, by centered on the predetermined Pivot axle that Z-direction extends in X/Y plane On rotatably constitute;Lens section is set on the turntable, can be with the rotation centered on the Pivot axle Platform is rotatably constituted together, is placed in the side on the turntable;Specimen holder is placed on the turntable, with the rotation Turn rotatably to constitute together with the turntable centered on central axis, and is placed in the lens section relative to the Pivot axle Opposite side, be rotatably connected at the turntable;And
Angle fixed part is placed on the turntable, and is positioned to that the angle of the specimen holder can be fixed;It is described Mirror portion is that have the plane of incidence that the side facing with the specimen holder is formed in predetermined plane;The specimen holder includes: rotation Axis extends along the y axis and is connected to the turntable;Rotor is connected to the rotation by the rotation axis one end Turntable, and be rotatably coupled in XZ plane centered on the rotation axis;And light source portion, it is placed in the rotor It is interior.The rotor is that have the loading surface that can place predetermined sample with the facing position of the lens section, by constituting As the rotor is rotated centered on the rotation axis, the angle between the loading surface and the plane of incidence becomes Change.The angle fixed part is to secure the above the position of specimen holder and make the angle between the loading surface and the plane of incidence Keep predetermined angular.Angle between the loading surface and the plane of incidence is fixed into the state of predetermined angular, by the light When the irradiation light that source portion generates is irradiated to the sample, the exciting light that the sample is excited and generates is put by the border portion It is shot out.
Embodiment
Illustrate the preferred embodiment of the present invention with reference to the accompanying drawing, but is not to limit the invention.
Advantages of the present invention, feature and in relation to technical solution by referring to accompanying drawing and in detail after the embodiment of book mentioned Show obviously.The present invention embodiment not limited to the following and may be implemented as a variety of different forms.The present embodiment It is intended merely to improve enlightenment of the invention and makes those skilled in the art that scope of the invention be understood completely and provide, and this Invention is only defined by the scope of scope of the claims.The same reference marks refers to that the same composition is wanted throughout the specification Element.
Term used herein is only to illustrate embodiment, is not to limit the present invention.In this specification, singular shape It also include plural form under the premise of formula does not have special suggestion in sentence.In specification use " including (comprises) " and Or " including (comprising) " description constituent element, step, movement and/or component be not precluded one or its more than Other constituent elements, step, movement and/or the presence of component or supplement.
Under the premise of no specifically defined, including technology or scientific term, all explicans as used herein It is identical as the meaning that the those of ordinary skill of technical field is commonly understood by.The term defined on usually used dictionary It is that, as long as not explicitly defined in this specification, should not be explained in the form of abnormal or is excessive.
Fig. 1 is the schematic diagram for showing the shape of sample detection means 1 of one embodiment of the invention, and Fig. 2 is the display present invention The schematic diagram of 30 open state of door on the shell 20 of the sample detection means 1 of one embodiment, Fig. 3 are to show sample of the invention The schematic diagram of the interior arrangement structure of detection device 1, fig. 4 to fig. 6 be respectively the top of Z-direction, Y direction side and The schematic diagram of Fig. 3 interior arrangement is checked in front of X-direction.
Here, X-direction, Y direction and Z-direction are to be subject to the direction illustrated in Fig. 3 respectively to illustrate.
The structure of sample detection means 1 of the invention may include: power part 100, turntable 200, lens section 300, sample Product frame 400, angle fixed part 500, light pass through portion 600, angle adjustment 700 and analytical equipment 800.The multiple device setting On scheduled substrate 10, the shell 20 that can be scheduled is covered.Furthermore the shell 20 can have the structure of the opening and closing of door 30.
Illustrate power part 100 first.
Power part 100 is to be entered scheduled electric power and provide rotary force.Power part 100 is fixedly installed on described in turn On substrate 10, and it is connected to scheduled power supply device and is entered scheduled electric power.
Power part 100 can have the scheduled power device 110 such as motor, cover outside the side in 110 outside of power device It shell 120 and is placed in 110 top of power device and covers the upper case 130 of power device 110.Power device 110 has can be with The scheduled axis for rotating turntable 200.
Illustrate turntable 200 below.
Turntable 200 is the component on X/Y plane with predetermined area, along the scheduled rotation that Z-direction extends It is rotated on X/Y plane centered on mandrel.
Specifically, turntable 200 has base station 210, upper cap 220 and interconnecting piece 230.
Base station 210 can be to be connected to the power part 100 and rotatably the scheduled disk-like member that is constituted is constituted. Specifically, it can connect the axis rotation in the power part 100.
The upper surface of base station 210 is divided into lens face 214 and basal plane 112.Lens face 214 and basal plane 112 are respectively provided with base The area of the upper surface of platform 210 about respectively divides 1/2 semicircle form.At this point, the height of lens face 214 is higher than basal plane 112 Degree is high, therefore the lens face 214 and basal plane 112 are distinguished centered on scheduled cascaded surface 216.The cascaded surface 216 with it is logical It crosses the diameter of 210 central point of disk-shaped base station unanimously or is formed side by side.
The basal plane 112 can the recessed groove 213 formed above with predetermined depth and recess.The recessed groove 213 is distinguished Be formed in the two sides along the y axis of aftermentioned angle fixed part 500, from the liquid of the outflow on aftermentioned sample not to It scatters outside, but concentrates in together and be properly handled.
Upper cap 220 is located at 214 top of lens face can form semicircle such as the shape of lens face 214 on the whole Shape.Aftermentioned lens section 300 is set between upper cap 220 and the basal plane 112.
Base station 210 is connected by interconnecting piece 230 in the up-down direction with upper cap 220.Specifically, the lower end of interconnecting piece 230 It is connected to the base station 210, upper end is connected to the upper cap 220.There are two interconnecting piece 230 is set, the tool of each interconnecting piece 230 Body setting is illustrated in aftermentioned content.
Illustrate lens section 300 below.
Lens section 300 is arranged on the turntable 200, can rotate together with turntable 200.
Specifically, lens section 300 can have the semicircle form of predetermined thickness.That is lens section 300 can be along Z Axis direction has predetermined thickness, the plane of incidence 310 constituted with plane is uprightly formed in front along the x axis, and along X-axis The rear in direction may be constructed to form shaped lens curved surface and the shaped lens with predetermined thickness.
Lens section 300 is placed on the lens face 214 on the base station 210.At this point, the plane of incidence 310 and the ladder Face 216 is disposed side by side.That is one side can be constituted side by side as shown in figure 4, the plane of incidence 310 is located on cascaded surface 216.Into And lens section 300 is concentrically disposed about with base station 210.Half diameter of a circle that lens section 300 is drawn can be less than half that lens face 214 is drawn Diameter of a circle.
Connect setting below the upper surface of lens section 300 and upper cap 200.Therefore lens section 300 is located at the base station 210 Between upper cap 220.And the both sides part of the plane of incidence 310 is connected on the interconnecting piece 230 respectively.And then it is described Interconnecting piece 230 touches the back side of the cascaded surface 216 simultaneously and the plane of incidence 310 and is fixed.
Therefore, covered below lens section 300 by the basal plane 112, the upper surface of lens section 300 by 220 Gai Zhu of upper cap, The both sides part of the plane of incidence 310 is covered by the interconnecting piece 230.The base station 210, upper cap 220 and interconnecting piece 230 Lens section 300 is secured the above, the lens section 300 can expose 310 central part of the plane of incidence being located in front of volume along the x axis Point, and the lens curved surface 320 positioned at rear along the x axis.
Illustrate specimen holder 400 below.
Specimen holder 400 is to load scheduled sample and to the device of the sample irradiation light.
Specimen holder 400 is placed on turntable 200, and can be placed on the basal plane 112.That is if the rank Base station 210 is divided into 1/2 by tread 216, then is equipped with lens section 300 across the side of the cascaded surface 216, and opposite side is equipped with sample Frame 400.
The structure of specimen holder 400 includes rotation axis 410, rotor 420 and light source portion 430.
Rotation axis 410 is made of the axis extended along the y axis, is connected to the turntable 200.It specifically, can be by inciting somebody to action The scheduled beam that connection is crossed between described two interconnecting pieces 230 is constituted.Rotation axis 410 is the axis by rotating rotor 420 Composition, therefore the embodiment that constitutes of the scheduled protrusion beam by being located on rotor 420 or interconnecting piece 230 can also be with.
Rotor 420 is internal equipped with light source portion 430, and one end passes through the rotation axis between the interconnecting piece 230 410 are connected to turntable 200, are the components rotationally constituted in XZ plane centered on the rotation axis 410.
Light source portion 430 can be scheduled light-emitting component, as an example, can be by the light of irradiation such as UV light specific wavelength Scheduled LED light-emitting component constitute.But it is not limited to this.
The structure of rotor 420 includes: cant beam 440, shell 450 and loading surface 460.
The cant beam 440 is the part that one end is connected to the rotation axis 410, to be connected to the rotation axis 410 and Rotatable scheduled beam is constituted.
The shell 450 is to install light source portion 430 and the internal part for forming scheduled space internal.It is described outer Shell 450 is connected to the other end of the cant beam 440, as the rotation of cant beam 440 rotates together.Cant beam 440 and shell 450 be that preferably, can have with the curved structure with mutual predetermined angle.
Shell 450 has light opening portion 452 at rear along the x axis.Light opening portion 452 is space opening or is equipped with The part for penetrating the components such as the window of material with scheduled light and passing light through.And then the light source by being installed in the shell 450 The irradiation light that portion 430 generates can be irradiated on sample.
The face that loading surface 460 is formed on the position facing with the lens section 300, after being located at the shell 450 Side.Scheduled sample can be stored on the loading surface 460, can be formed sample on loading surface 460 and be contained fixed make a reservation for Slot.For example, being formed and box or quadrangle when the sample is the box or scheduled quadrangle glass equipped with predetermined liquid sample The corresponding slot of glass shape is put into the box or quadrangle glass and comes.
The loading surface 460 is connected to the light opening portion 452 of the shell 450, is accommodated into the sample described On loading surface 460, the front part of the sample is to be made up of face to face the smooth opening portion 452 with the light source portion 430, It is mapped to the illumination generated from the light source portion 430 on the sample.
Rotor 420 can also include the securing fixed device 470 of sample position being placed on loading surface 460.Institute The top that the loading surface 460 is arranged in fixed device 470 is stated, structure may include rotating small axis 472 and rotation fixed pin 474。
Specifically, the fixed device 470 can be placed in the top of the loading surface 460, and there is the rotation to fix One end of pin 474 is rotatably connected at the structure on the small axis 472 of rotation extended along the y axis.The rotation fixed pin 474 It can be rotated in XZ plane centered on the small axis 472 of rotation.The other side of the rotation fixed pin 474 is equipped at this time Scheduled retaining lugs, a part covering above the sample being placed on the loading surface 460 and the position for securing the above sample It sets.
As the rotor 420 rotates, the inclination angle of the loading surface 460 can also change.The loading surface 460 It is to form the state with the predetermined angle of 310 flare up of the plane of incidence, or enter described in abutting with the rotation of rotor 420 Face 310 is penetrated, 0 ° of angle between the plane of incidence 310 and loading surface 460 of state is made.
That is specimen holder 400 has open mode and closed mode.In closed mode, rotor 420 is with rotation axis It is laterally rotated centered on 410 to the lens section 300, the plane of incidence 310 is mutually separated with loading surface 460, the plane of incidence Scheduled angle is formed between 310 and loading surface 460, loading surface 460 exposes upwards, and then the sample is loaded into loading On face 460.
In closed mode, the angle between the plane of incidence 310 and loading surface 460 is 0 °.The cant beam 440 is straight at this time It is vertical, mutually it is close between loading surface 460 and the plane of incidence 310.Further correctly, it can be understood as be placed in loading surface 460 Sample is close to the plane of incidence 310.
Illustrate angle fixed part 500 below.
Angle fixed part 500 is placed in the front of the specimen holder 400 in the X direction, and the specimen holder 400 can be made to keep Certain tilt angle.
The angle fixed part 500 is placed on the basal plane 112 of the base station 210, and structure may include base clamp 510 With rotary clamp 520.
Base clamp 510 is fixed on the basal plane 112 of the base station 210, is located at the specimen holder 400 in the X-axis direction Front.The scheduled slot to connect rotary clamp 520 can be set in the two sides along the y axis of base clamp 510.
The rotary clamp 520 is located at the two sides of the base clamp 510 in Y direction, passes through the base clamp 510 It is rotatably coupled with scheduled support shaft 514.The support shaft 514 extends along the x axis and the rotary clamp 520 exists It is rotationally constituted in XZ plane.And then the rotary clamp 520 have lie on the basal plane 112 with 112 phase of basal plane The horizontal pattern that faces and, rotated and 112 shape of basal plane angle in 90 ° and formed upright centered on the support shaft 514 The vertical mode of state.But 90 ° are not limited to the angle of basal plane 112 on vertical mode, but there is appropriate angle.
Explanation is fixed by the position of the specimen holder 400 of the angle fixed part 500 below.
The specimen holder 400 when being in off state the cant beam 400 become upright state.At this point, making the rotating clip Tool 520 is rotated centered on the support shaft 514, after so that horizontal pattern is switched to vertical mode, after the rotary clamp 520 Face is touched before the cant beam 440.In turn, the rotary clamp 520 supports before the cant beam 440 and keeps turning The posture of dynamic beam 440, and cant beam 440 is made to remain turned-off mode.Preferably, the rotary clamp 520, which has, is suitable for described Specimen holder 400 can keep the length and configuration of correct upright state in the state of closing.That is the rotary clamp 520 With the rotary clamp 520 along the x axis behind can be close to the sample under 400 upright state of specimen holder The length and configuration of 400 front of frame.
Light is the component for being above located at the rear of the lens section 300 along the x axis by portion 600, described in order to pass through Only have the light in predetermined position to be selected to pass through in the light that mirror portion 300 penetrates, can have scheduled slit 610 and lens 620.Light By portion 600 can the scheduled works by being fixed on substrate 10 constitute.
Angle adjustment 700 by be adjusted the rotation angle of the turntable 200, rotation angle range, rotation speed and The device of initial angle etc. is constituted.Angle adjustment 700 can be connected and composed with the power part 100, make scheduled adjustment pin Rotate and adjust the initial angle etc. of the turntable 200.For example, the adjustment pin can be connected to by scheduled sawtooth etc. The turntable 200.
Analytical equipment 800 is not illustrate in Fig. 1 into Fig. 6, but can be located at relative to the light by portion 600 described The opposing face of lens section 300.Therefore it can be incident in analytical equipment 800 by light by the light in portion 600.Analytical equipment 800 It can use from the light analysis that light is passed through by portion 600 and obtain scheduled testing result after handling various signals.Therefore it analyzes The composition of device 800 may include arithmetic unit, database, signal processing apparatus, display device and input unit.
The power part 100, turntable 200, lens section 300, specimen holder 400, angle fixed part 500, light pass through portion 600 and analytical equipment 800 be arranged on scheduled substrate 10, and all devices can be accommodated in scheduled shell 20.Institute Stating shell 20 is open structure, can open the door 30 on shell 20 and put sample into or each device is replaced and tieed up It repairs.Can have scheduled output device and input unit on shell 20.
Detection reliability is further promoted in order to exclude other light other than the light for detection, shines and light penetrates Component other than other components can be applied or tint into mass colour or.That is removing the lens section 300, specimen holder 400 a part and light can be coated with or tint into black by the part other than the slit 610 in portion 600 and lens etc., from And it prevents unnecessary reflected light, exterior light etc. and is incident in analytical equipment 800.Therefore the inner face of the inner face of shell 20, door 30 Outside with each component can painted black.
Illustrate the operation of sample detection means 1 of the invention below.
Fig. 7 is to show that sample is loaded onto sample when the specimen holder 400 of sample detection means 1 of the invention is open mode The schematic diagram of state when frame 400, Fig. 8 to Figure 10 are the schematic diagrames for showing the operation of sample detection means 1 of the invention.But Fig. 1 To Fig. 6 display portion referring also to.
First as shown in fig. 7, under the open mode of above explained specimen holder 400, sample P is put into the specimen holder On 400 loading surface 460.That is as shown in fig. 7, the exposing upwards of loading surface 460 can be by sample under open mode Product P is put on the loading surface 460.Then after putting sample into loading surface 460, by the arrow of the fixed device 470 such as Fig. 8 Rotation, is fixed on sample on the loading surface 460 shown in Q.
As described above, the scheduled glass that sample (P) can be box or be put into liquid sample etc., suitably puts loading surface into After 460, it is fixed by the fixed device 470.
According to an example, the sample P has transmissive portions G, and the transmissive portions G is pre- with the scheduled test sample F's of placement Determine area, and by having the material of translucency to constitute as glass, the refractive index of the transmissive portions G and the lens section 300 Refractive index it is identical.The sample may include being painted in the test sample being placed on the transmissive portions G and making the detection The liquid solvent being close between sample F and the plane of incidence 310 of transmissive portions G and the lens section 300.Preferably, the liquid The refractive index of solvent and the refractive index of the lens section 300 can be identical.
As described above, after the dispensing of sample P is completed as shown in the arrow R of Fig. 8, the specimen holder 400 being rotated, is cut Change to above-mentioned closed mode.That is specimen holder 400 is rotated, the sample for putting loading surface 460 into is made to be close to the plane of incidence 310.
At this point, after making the specimen holder 400 be switched to above-mentioned closed mode, make the angle fixed part 500 by level Pattern switching is vertical mode.The pattern switching of this angle fixed part 500 is can the implementation as shown in the arrow W of Fig. 5.It is exactly It says, makes before specimen holder 400 described in 520 rotational support of rotary clamp.The loading surface 460 of the specimen holder 400 therewith The state of the plane of incidence 310 can be held against with sample.
At this time if the sample P includes fluid test sample etc., liquid substance can be to flowing down.At this time as described above, Recessed groove 213 is formed on basal plane 112 and makes the liquid substance product of outflow here, to prevent liquid substance from flowing to other places pollution dress It sets.
Then as shown in figure 9, the light source portion 430 is entered after power supply, irradiation light is generated in the light source portion 430 L1.According to the structure of rotor 420 as described above, irradiation light L1 can be incident on downwards the sample above diagonal line On.The incident angle of the irradiation light L1 can determine according to angle between the cant beam 440 and shell 450, preferably 45 °, but it is not limited to this.
The irradiation light L1 is irradiated to after the sample, the illuminated smooth L1 of the liquid test sample for including in the sample It excites and generates exciting light L2, L3.Described exciting light L2, L3 are spread by the lens section 300.
The light for having scheduled slit 610 as described above at this time is located at the rear of the lens section 300 by portion 600, and The analytical equipment 800 that the only exciting light L2 with scheduled incidence angle is selected to be incident on rear.According to Fig. 8, the sample Frame 400, sample, lens section 300, light are arranged in a straight line by portion 600, therefore the exciting light on the only described straight line L2 is incident on analytical equipment 800, can prevent from being incident on analytical equipment to the unnecessary irradiation light of detection, reflected light etc. therewith 800 and accurately detected.At this time as described above, the transmissive portions of sample, liquid solvent are identical with the refractive index of lens section 300, Transmissive portions and lens section 300 are close to, therefore laser hair will not be refracted, but the exciting light on a straight line is incident on analytical equipment In 800.
Then scheduled operation button is operated, after the power part 100 generates rotary force, as shown in the arrow T of Fig. 4, institute Stating turntable 200 can rotate.As turntable 200 rotates, the direction angle of the sample P and lens section 300 changes, and such as schemes Shown in 10 arrow S, the orientation of lens section 300 is converted.Then the exciting light L3 with different incidence angles, which is located at, connects the sample Analytical equipment 800 is incident on the straight line that product, lens section 300, light pass through portion 600.Exciting light L2 will not be incident at this time Analytical equipment 800 as described above, being black inside shell 20, therefore will not be reflected, but is absorbed, to exclude to make an uproar Sound.
According to the present invention, sample detection is extremely simple, has reliability.In particular, sample can be close to lens section 300, from sample The exciting light generated on product is spread by lens section 300, by the exciting light of the diffusion, according to special angle selection capture into Row analysis, to correctly be analyzed.
Device is integrally covered by shell 20, and the irradiation light and exciting light irradiated from light source portion 430 will not reveal outside, thus User is prevented to be exposed under harmful light.The light especially irradiated by light source portion 430 may have human body if it is short-wavelength lights such as UV Evil, but the present invention is in use process, and light is not because shell dew is gone out, so that safety is detected.
Figure 11 is the schematic diagram for showing the sample detection mode of one embodiment of the invention, and Figure 12 is show testing result one The schematic diagram of example.
As shown in figure 11, according to the present invention, lens section 300 and sample P rotate and the light quilt of special angle as shown by arrow R It is selected into and is mapped to analytical equipment 800.Then the optical imagery of respective angles is acquired and is applied to detection.Such result is as analyzed The setting of device 800 covers the full slewing area of lens section 300.
For example, when the exciting light of analytical equipment is incident in analysis from special angle, it can be according to the strong of incident exciting light Degree obtains the result such as Figure 12 (a).That is exciting light incident from special angle have various wavelength, and it is described enter The intensity for penetrating light can also occur together.The incident light is analyzed it can be concluded that testing result, for example, entering to 520nm wavelength The testing result penetrated subject to light can show testing result shown in Figure 12 (b).
Although the present invention is described in detail referring to the foregoing embodiments, the present invention is but not limited to above-mentioned specific reality Example is applied, the present invention is deformed without departing from the intention of the invention required in scope of the claims by those skilled in the art Or modification.These deformations or modification should not discretely understand from technical idea or prospect of the invention.

Claims (16)

1. a kind of sample detection means (1), comprising:
Power part (100) provides rotary force;
Turntable (200) with predetermined area and is connected to the power part (100), with the predetermined rotation extended along Z-direction Turn rotatably to constitute on X/Y plane centered on central axis;
Lens section (300) is set on the turntable (200), centered on the Pivot axle with the turntable (200) it rotatably constitutes together, is placed in the side on the turntable (200);
Specimen holder (400) is placed on the turntable (200), centered on the Pivot axle with the turntable (200) it rotatably constitutes together, and is placed in the opposite side of the lens section (300) relative to the Pivot axle, can turn It is connected to the turntable (200) dynamicly, and fixes sample;And
Angle fixed part (500) is placed on the turntable (200), and is constructed to be permeable to fix the specimen holder (400) Angle,
Wherein, the lens section (300) has the plane of incidence that the side opposite with the specimen holder (400) is formed in predetermined plane (310);
The specimen holder (400) includes:
Rotation axis (410) extends along the y axis and is connected to the turntable (200);
Rotor (420), one end are connected to the turntable (200) by the rotation axis (410), and with the rotation axis (410) it is rotatably coupled in XZ plane centered on;And
Light source portion (430) is placed in the rotor (420),
The rotor (420) has the loading that can place predetermined sample with the facing position of the lens section (300) Face (460), as the rotor (420) is rotated centered on the rotation axis (410), the loading surface (460) and described Angle between the plane of incidence (310) can change,
The angle fixed part (500) fixes the position of the specimen holder (400) and makes the loading surface (460) and the incidence Angle between face (310) keeps predetermined angular,
In the state that angle between the loading surface (460) and the plane of incidence (310) is fixed into predetermined angular, by described The irradiation light that light source portion (430) generates is when being irradiated to the sample, the sample be excited and the exciting light that generates pass through it is described Saturating border portion (300) and project.
2. sample detection means (1) according to claim 1, wherein
The lens section (300) has predetermined thickness along Z-direction,
The lens section (300) along the x axis before be uprightly formed with the plane of incidence (310),
The lens section (300) along the x axis behind be formed with and be formed as the shaped lens of semicircle curved surface.
3. sample detection means (1) according to claim 1, wherein
The rotor (420) includes:
Cant beam (440), one end are connected to the rotation axis (410);
Shell (450), is connected to the other end of the cant beam (440), and has space with by the light source portion in inside (430) it is installed on inside;And
The loading surface (460) setting is at the rear along the x axis of the shell (450) and the lens section (300) phase The position faced.
4. sample detection means (1) according to claim 3, wherein
When the cant beam (440) is upright, the angle between the loading surface (460) and the plane of incidence (310) becomes 0 °, peace The plane of incidence (310) of the sample and the lens section (300) that are placed on the loading surface (460) is mutually close to.
5. sample detection means (1) according to claim 4, wherein
The cant beam (440) and the shell (450) are bent with mutually having predetermined angle,
Light is diagonally irradiated to institute in the state that the cant beam (440) is upright by the light source portion (430) in downward direction State sample.
6. sample detection means (1) according to claim 3, wherein
The rotor (420) includes the fixation device (470) that the position of the sample on the loading surface (460) is fixed,
The fixed device (470) is placed in the top of the loading surface (460) and includes:
The small axis of the rotation extended along the y axis (472);
The rotation fixed pin (474) rotated in XZ plane centered on the small axis (472) of rotation,
When placing the sample on the loading surface (460), the rotation fixed pin (474) is configured to cover the sample The position of a part of upper end and the fixed sample.
7. sample detection means (1) according to claim 1, wherein
The angle fixed part (500) is located at the front of the specimen holder (400) along the x axis and includes:
Base clamp (510) is fixed on the turntable (200);And
Rotary clamp (520) is rotationally constituted and the fixed specimen holder (400) relative to the base clamp (510) Position.
8. sample detection means (1) according to claim 7, wherein
The rotary clamp (520) along the y axis on be placed in the two sides of the base station, with the support shaft extended along the x axis (514) it is rotated centered on,
In the state that the specimen holder (400) is upright, the rotary clamp (520) centered on the support shaft (514) to When upper rotation, the rotary clamp (520) support the specimen holder (400) along the x axis before and the fixed sample The position of frame (400).
9. sample detection means (1) according to claim 1, wherein
The turntable (200) includes:
Base station (210) is connected to the power part (100);
Upper cap (220) covers the upper surface of the lens section (300);And
Interconnecting piece (230) is set to the two sides of the specimen holder (400) in the Y-axis direction and stands upright on the base station (210) On, connect the base station (210) and the upper cap (220), and behind the interconnecting piece (230) with the lens section (300) the plane of incidence (310) connects.
10. sample detection means (1) according to claim 9, wherein
The base station (210) has circular shape,
The upper surface of the base station (210) be divided into the semi-circular shape with mutually different height lens face (214) and Basal plane (112), the height of the lens face (214) lower than the basal plane (112) height and in the lens face (214) and institute Formation cascaded surface (216) between basal plane (112) is stated,
The lens section (300) are equipped on the lens face (214),
Illumination part and angle fixed part (500) are equipped on the basal plane (112).
11. sample detection means (1) according to claim 10, wherein
The plane of incidence (310) of the cascaded surface (216) and the lens section (300) is mutually located at the same face and constitutes one side.
12. sample detection means (1) according to claim 10, wherein
Fluid slot is formed on the basal plane (112), the fluid slot is formed in the outside of the angle fixed part (500), With scheduled depth, inside is filled with scheduled liquid.
13. sample detection means (1) according to claim 1, wherein
The sample has transmissive portions, and the transmissive portions have the predetermined area for placing scheduled test sample, and saturating by having The material of photosensitiveness is constituted,
The refractive index of the transmissive portions is identical as the refractive index of the lens section (300).
14. sample detection means (1) according to claim 13, wherein
The sample includes liquid solvent, and the liquid solvent, which is painted on, to be placed in the test sample on the transmissive portions, makes institute The plane of incidence (310) for stating test sample and transmissive portions and the lens section (300) is in close contact;
The refractive index of the liquid solvent is identical as the refractive index of the lens section (300).
15. sample detection means (1) according to claim 1, further includes:
Light is placed in the rear of the lens section (300), and described can make to penetrate by portion (600) in the X-axis direction The light in mirror portion (300) has predetermined slit (610) by way of;And
Analytical equipment (800) receives and passes through the light of portion (600) by the light and analyze the light.
16. sample detection means (1) according to claim 1 further include angle adjustment (700), the angular adjustment Portion (700) can adjust the rotation angle and initial angle of the turntable (200).
CN201680084836.1A 2016-04-21 2016-04-29 Sample detection device Active CN109073552B (en)

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