CN109069592B - 纯化胶原7的方法 - Google Patents

纯化胶原7的方法 Download PDF

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Publication number
CN109069592B
CN109069592B CN201780015536.2A CN201780015536A CN109069592B CN 109069592 B CN109069592 B CN 109069592B CN 201780015536 A CN201780015536 A CN 201780015536A CN 109069592 B CN109069592 B CN 109069592B
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recombinant human
human collagen
collagen
purified
effluent
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Chinese (zh)
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CN109069592A (zh
Inventor
I·基尼奥内斯-加西亚
B·西蒙尼
R·利利
杨婷
D·尼克尔斯
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Phoenix Organization Rehabilitation Co
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Phoenix Organization Rehabilitation Co
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Water Supply & Treatment (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN201780015536.2A 2016-03-16 2017-03-10 纯化胶原7的方法 Active CN109069592B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662309030P 2016-03-16 2016-03-16
US62/309,030 2016-03-16
PCT/US2017/021815 WO2017160636A1 (en) 2016-03-16 2017-03-10 Methods of purifying collagen 7

Publications (2)

Publication Number Publication Date
CN109069592A CN109069592A (zh) 2018-12-21
CN109069592B true CN109069592B (zh) 2023-03-07

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CN201780015536.2A Active CN109069592B (zh) 2016-03-16 2017-03-10 纯化胶原7的方法

Country Status (7)

Country Link
US (1) US10669327B2 (https=)
EP (1) EP3429615A4 (https=)
JP (2) JP6985282B2 (https=)
CN (1) CN109069592B (https=)
CA (1) CA3015685A1 (https=)
MX (1) MX2018011162A (https=)
WO (1) WO2017160636A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108463470B (zh) * 2015-12-23 2021-10-22 菲尼克斯组织修复公司 胶原蛋白7的组合物及其使用方法
US11180541B2 (en) 2017-09-28 2021-11-23 Geltor, Inc. Recombinant collagen and elastin molecules and uses thereof
US10792618B2 (en) * 2018-06-19 2020-10-06 Sartorius Stedim Biotech Gmbh Particle separation and/or purification of a fluid
EP3953380A4 (en) 2019-04-12 2023-01-25 Geltor, Inc. RECOMBINATION ELASTIN AND ASSOCIATED PRODUCTION
EP4061446A4 (en) 2019-11-20 2023-11-29 NxStage Medical, Inc. METHODS, DEVICES AND SYSTEMS FOR PROVIDING PERITONEAL DIALYSIS LIQUID FROM A POWDERED CONCENTRATE
CN113121638B (zh) * 2020-01-15 2022-06-14 鲁南制药集团股份有限公司 一种纯化重组蛋白的方法
GB2610313B (en) 2020-01-24 2024-07-03 Geltor Inc Animal-free dietary collagen
US11504716B2 (en) * 2020-06-05 2022-11-22 Pall Corporation Multiwell device and method of use
EP4225353A1 (en) * 2020-10-08 2023-08-16 Jellatech, Inc. Produce, isolate and/or extract collagen and/or gelatin from animal cell lines and/or tissue explants
KR20240004264A (ko) * 2021-03-04 2024-01-11 젤라텍, 인크. 배양된 동물 세포로부터의 콜라겐을 사용한 재료의 제조 방법
CN114805548B (zh) * 2021-12-29 2023-11-14 江苏创健医疗科技股份有限公司 一种重组胶原蛋白冻干纤维及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012149136A1 (en) * 2011-04-26 2012-11-01 The Board Of Trustees Of The Leland Stanford Junior University Production and delivery of a stable collagen
US20130338344A1 (en) * 2012-04-20 2013-12-19 Abbvie Inc. Protein purification methods to reduce acidic species
CN103842517A (zh) * 2011-08-03 2014-06-04 莲花组织修复公司 胶原蛋白7及相关方法

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Publication number Priority date Publication date Assignee Title
AUPO599897A0 (en) * 1997-04-03 1997-05-01 Vidal, Linus Clear collagen for facial implants
US7855280B2 (en) 2005-09-15 2010-12-21 Wyeth Llc Separation methods
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US20140031295A1 (en) * 2012-07-19 2014-01-30 Lotus Tissue Repair, Inc. Recombinant C7 and Methods of Use
CN112126634A (zh) 2013-01-09 2020-12-25 夏尔人类遗传性治疗公司 含用于纯化芳基硫酸酯酶a的方法
KR20160055940A (ko) 2013-09-24 2016-05-18 엘라스타겐 피티와이 리미티드 단백질 추출 방법

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012149136A1 (en) * 2011-04-26 2012-11-01 The Board Of Trustees Of The Leland Stanford Junior University Production and delivery of a stable collagen
CN103842517A (zh) * 2011-08-03 2014-06-04 莲花组织修复公司 胶原蛋白7及相关方法
US20130338344A1 (en) * 2012-04-20 2013-12-19 Abbvie Inc. Protein purification methods to reduce acidic species

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
The recombinant expression of full-length type VII collagen and characterization of molecular mechanisms underlying dystrophic epidermolysis bullosa;Chen M等;《Journal of Biological Chemistry》;20020118;第277卷(第3期);第2118-2124页 *

Also Published As

Publication number Publication date
EP3429615A4 (en) 2019-11-06
JP2022016605A (ja) 2022-01-21
JP6985282B2 (ja) 2021-12-22
CA3015685A1 (en) 2017-09-21
CN109069592A (zh) 2018-12-21
EP3429615A1 (en) 2019-01-23
US10669327B2 (en) 2020-06-02
JP7340583B2 (ja) 2023-09-07
WO2017160636A1 (en) 2017-09-21
US20190077845A1 (en) 2019-03-14
JP2019511498A (ja) 2019-04-25
MX2018011162A (es) 2018-11-22

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