CN109055054A - A kind of mosquito-expelling and antipruritic handmade soap and preparation method thereof - Google Patents
A kind of mosquito-expelling and antipruritic handmade soap and preparation method thereof Download PDFInfo
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- CN109055054A CN109055054A CN201811184244.4A CN201811184244A CN109055054A CN 109055054 A CN109055054 A CN 109055054A CN 201811184244 A CN201811184244 A CN 201811184244A CN 109055054 A CN109055054 A CN 109055054A
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/02—Compositions of detergents based essentially on soap on alkali or ammonium soaps
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/12—Asteraceae or Compositae [Aster or Sunflower family], e.g. daisy, pyrethrum, artichoke, lettuce, sunflower, wormwood or tarragon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/005—Synthetic soaps
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/04—Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
- C11D9/22—Organic compounds, e.g. vitamins
- C11D9/38—Products in which the composition is not well defined
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
The present invention relates to a kind of mosquito-expelling and antipruritic handmade soaps and preparation method thereof, raw material includes 4-12 parts of Asian puccoon, 140-160 parts of olive oil, 50-100 parts of palm oil, 50-100 parts of coconut oil, 50-100 parts of sesame oil, 40-75 parts of sodium hydroxide, 120-140 parts of water, it further include folium artemisiae argyi, honeysuckle and elsholtzia splendens oil, the present invention is with Asian puccoon, folium artemisiae argyi, honeysuckle is mosquito repellent, antipruritic active constituent, under the action of elsholtzia splendens oil, substantially increase Asian puccoon, the repelling effect of folium artemisiae argyi, the irritation to skin is avoided simultaneously, avoid skin dry, also there is good antipruritic effect simultaneously, augmenting tissue amine causes threshold values of itching, both the surface of a wound can be made not to be infected by bacterial, be conducive to the reparation of skin histology again.
Description
Technical field
The invention belongs to washing product fields, and in particular to a kind of mosquito-expelling and antipruritic handmade soap and preparation method thereof.
Background technique
Current market sales of perfumed soap, mostly uses chemical substance to be synthetically prepared, and in process of production, what good fortune obtained
Glycerol can be generally pulled out, and will lead to that skin is dry and astringent, coarse, some commercially available perfumed soap alkalinities are too high without the perfumed soap of glycerol,
The natural grease on human skin can not only be washed away, it is also possible to skin and environmental concerns.
Occurs a kind of more popular handmade soap in recent years.Handmade soap refers to the perfumed soap that oneself DIY is worked it out, and has
Foam exquisiteness is abundant, can thoroughly remove the effect of the greasy dirt of pore depths, moreover, because the grease after being saponified in handmade soap does not have
It is pulled out, therefore there is better moistening effect, more mildly.More importantly the moulding of handmade soap is colourful, it is people
Provide unlimited imagination space and Creative spaces, people can be allowed to give full play to the individual character of oneself, enjoy the enjoyment of DIY,
Therefore gradually liked in recent years by people.
Summer is mosquito movable high-incidence period, and people are often by the pain of bite by mosquitos, night mosquito buzz
Also the sleep that people can be bothered influences people and normally lives, works, learns and sleep.Currently, many chemical synthesis substances can
To have the function that mosquito repellent or mosquito, but a large amount of uses due to chemical synthesis repellant for a long time, have resulted in
Mosquito drug resistance is continuously improved, and not only repelling effect declines year by year, and can cause neurological symptom and skin injury.Closely
Common report of the abuse to children and all kinds of adverse consequences of premature labor in pregnant women because synthesizing repellant of Nian Laijing, so more and more
Researcher is transferred to attention on natural plants repellant.
With the continuous improvement of people's living standards, people get over the safety of daily necessity, health and diversity
More pay attention to, the requirement of people, especially women to perfumed soap not only rests on cleaning aspect, and preferring to perfumed soap has
The functions such as anti-inflammatory, antibacterial, mosquito repellent, antipruritic, to promote quality of life.
For another example, Chinese patent literature CN106085661A discloses a kind of mosquito proof handmade soap and preparation method thereof, mosquito proof
Handmade soap is by pelargonium oil, tea tree ethereal oil, galic essential oil, lemon extract, lavender petal, Milan flower petal, eucalyptus branch, mandarin orange
The raw materials such as skin, peppermint, fennel, cloves, rosemary, You Jiali, lemongrass, pseudo-ginseng, wormwood, sweet basil, thyme are made, the handmade soap
Complicated component, it is at high cost.
Therefore, it is necessary to research and develop a kind of low cost, while having both the handmade soap of mosquito repellent and antipruritic effect.Summary of the invention
In view of the deficiencies of the prior art, the present invention provides a kind of mosquito-expelling and antipruritic handmade soap and preparation method thereof, and the handmade soap is not only
Dirt-removing power is strong, meanwhile, it is easy to be decomposed in nature, noresidue is free of a burden to human body, and has mosquito repellent and antipruritic function
Energy.
Technical scheme is as follows:
A kind of mosquito-expelling and antipruritic handmade soap, raw material include as follows, are parts by weight,
4-12 parts of Asian puccoon, 140-160 parts of olive oil, 50-100 parts of palm oil, 50-100 parts of coconut oil, 50-100 parts of sesame oil,
40-75 parts of sodium hydroxide, 120-140 parts of water.
Preferred according to the present invention, it is parts by weight that mosquito-expelling and antipruritic handmade soap, raw material, which includes as follows,
8-12 parts of Asian puccoon, 150-160 parts of olive oil, 60-75 parts of palm oil, 60-75 parts of coconut oil, 60-75 parts of sesame oil, hydrogen-oxygen
Change 4555 parts of sodium, 120-130 parts of water.
Preferred according to the present invention, the mosquito-expelling and antipruritic handmade soap, raw material further includes honeysuckle, and the weight of honeysuckle accounts for olive
The 1-8% of olive oil weight.
It is further preferred that the weight of honeysuckle accounts for the 2-5% of olive oil weight.
Preferred according to the present invention, the mosquito-expelling and antipruritic handmade soap, raw material further includes folium artemisiae argyi, and the weight of folium artemisiae argyi accounts for olive oil
The 1-8% of weight.
It is further preferred that the weight of folium artemisiae argyi accounts for the 1-3% of olive oil weight.
Preferred according to the present invention, the mosquito-expelling and antipruritic handmade soap, raw material further includes elsholtzia splendens oil, elsholtzia splendens oil
Weight content is 8-20%.
It is further preferred that the weight content of elsholtzia splendens oil is 10-14%.
Another object of the present invention is to provide a kind of preparation method of mosquito-expelling and antipruritic handmade soap.
A kind of preparation method of mosquito-expelling and antipruritic handmade soap, comprises the following steps that
(1) Asian puccoon, folium artemisiae argyi and honeysuckle are added in olive oil sealed soak 10~15 days, obtain mixture；
(2) mixture intense fire is heated to boiling, and mild fire heats 20min~30min under agitation, is separated by filtration removal medicine
Slag obtains filtrate；
(3) sodium hydroxide is poured into water by several times, it is stirring while adding, until melting completely, obtain buck；
(4) coconut oil, palm oil, sesame oil, elsholtzia splendens oil and the filtrate of step (2) are heated to 35-45 DEG C, must mixed
Oil；
(5) make buck temperature consistent with mixing oil temperature, buck is added in miscella, side edged persistently stirs 5-20min, obtains
The semi-finished product being thoroughly mixed；
(6) semi-finished product are poured into mold, after solidification, is demoulded to get mosquito-expelling and antipruritic handmade soap.
Present invention excellent results compared with existing conventional techniques are as follows:
1, the present invention is using Asian puccoon, folium artemisiae argyi, honeysuckle as mosquito repellent, antipruritic active constituent, under the action of elsholtzia splendens oil, significantly
The repelling effect of Asian puccoon, folium artemisiae argyi is improved, while avoiding the irritation to skin, avoids skin dry, while also being had very
Good antipruritic effect, augmenting tissue amine cause threshold values of itching.
2, the present invention use Asian puccoon, folium artemisiae argyi, honeysuckle for raw material, without chemicals, whole preparation process use oil immersion,
Oil mentions oil sealing, ensure that product moisture-free, product germy will not be bred without adding preservative.Decoction process makes
Chinese herbal medicine effective ingredients are fully dissolved out, and effect is more prominent, and can make the microorganism killing of medicinal material and other raw materials institute band, ensure that
Effective component evaporates toxic ingredient not by microbial destruction, has dispelled to the harmful substance of skin.
3, handmade soap of the invention is in use, Asian puccoon, folium artemisiae argyi, honeysuckle oil immersion, the effective component of oil proposition and Haizhou are fragrant
Ru is stayed in skin surface, and elsholtzia splendens are conducive to ingredient draws, can not only the surface of a wound be made not to be infected by bacterial, but also be conducive to skin
The reparation of tissue.
Specific embodiment
Below with reference to embodiment, the present invention will be further described, and non-elaborate is existing by this field in embodiment
Technology.
Raw material coconut oil, palm oil used in embodiment, sesame oil, elsholtzia splendens oil are existing product, by city
Field is bought.
Embodiment 1
A kind of mosquito-expelling and antipruritic handmade soap, raw material include as follows, are parts by weight,
8 parts of Asian puccoon, 4 parts of folium artemisiae argyi, 6 parts of honeysuckle, 160 parts of olive oil, 65 parts of palm oil, 65 parts of coconut oil, 65 parts of sesame oil, sea
70 parts of state elsholtzia oil, 51 parts of sodium hydroxide, 128 parts of water.
Preparation method, steps are as follows:
(1) Asian puccoon, folium artemisiae argyi and honeysuckle are added in olive oil sealed soak 15 days, obtain mixture；
(2) mixture intense fire is heated to boiling, and mild fire heats 30min under agitation, is separated by filtration the removal dregs of a decoction, obtains
Filtrate；
(3) sodium hydroxide is poured into water by several times, it is stirring while adding, until melting completely, obtain buck；
(4) coconut oil, palm oil, sesame oil, elsholtzia splendens oil and the filtrate of step (2) are heated to 38 DEG C, obtain miscella；
(5) making buck temperature consistent with mixing oil temperature, buck is added in miscella, side edged persistently stirs stirring 20min,
The semi-finished product that must be thoroughly mixed；
(6) semi-finished product are poured into mold, after solidification, is demoulded to get mosquito-expelling and antipruritic handmade soap.
Embodiment 2
A kind of mosquito-expelling and antipruritic handmade soap, raw material include as follows, are parts by weight,
4 parts of Asian puccoon, 4 parts of folium artemisiae argyi, 8 parts of honeysuckle, 160 parts of olive oil, 50 parts of palm oil, 60 parts of coconut oil, 75 parts of sesame oil, sea
80 parts of state elsholtzia oil, 60 parts of sodium hydroxide, 132 parts of water.
The preparation method is the same as that of Example 1.
Comparative example 1
A kind of mosquito-expelling and antipruritic handmade soap, component with embodiment 1, the difference is that, the component do not include elsholtzia splendens oil.
The preparation method is the same as that of Example 1.
Comparative example 2
A kind of mosquito-expelling and antipruritic handmade soap, component with embodiment 1, the difference is that, which does not include folium artemisiae argyi and honeysuckle.
The preparation method is the same as that of Example 1.
Experimental example:
One, repelling effect is tested
The verifying of repelling effect
Attack test must be carried out to the volunteers and aedes albopictus for participating in test before testing, test is referring to GB/13917.9-
2009 methods carry out.Method are as follows: 300 test worms are put into the mosquito cage of a height of 40cm * 30cm * 30cm of long * wide *, it will
The skin of the back of the hand exposure 4cm*4cm of testing crew, rest part protrude into after tightly covering and place 2min in mosquito cage, come to stop
More than 15 persons of the test worm fallen are that attack is qualified, and this person and mosquito cage can be used for repellency test.In the aspiration of attack qualification
The both hands back of personnel respectively draws the skin surface of 5cm*5cm, and a hand is soaped with the craft of embodiment 1- and comparative example 1-2
After hand, hand is protruded into 2min in the mosquito cage of attack qualification by the skin of exposure 4cm*4cm therein, and whether there is or not mosquitoes to come for observation
It sucks blood, later 1h is tested 1 time, as long as there is 1 mosquito to come to suck blood to be judged to repellant failure, test effect see the table below 1.
Scattering ratio/%=(control aedes albopictus number-processing aedes albopictus number)/control aedes albopictus number * 100
1 scattering ratio of table and mosquito repellent time
| Project | Scattering ratio % | Repelling effect (time) |
| Embodiment 1 | 90.28 | 10.2 |
| Embodiment 2 | 91.35 | 8.4 |
| Comparative example 1 | 47.15 | 5.2 |
| Comparative example 2 | 58.63 | 4.8 |
It can be seen from Table 1 that comparative example 1 do not contain elsholtzia splendens oil handmade soap, repelling effect be markedly less than it is of the invention,
This illustrates that elsholtzia splendens oil can increase repelling effect, although comparative example 2 lacks folium artemisiae argyi and honeysuckle containing elsholtzia splendens oil,
Repelling effect relative contrast example 1 improves to some extent, but repelling effect is still less than of the invention, it can thus be seen that the present invention is
Reach efficient repelling effect under Asian puccoon, folium artemisiae argyi, honeysuckle and elsholtzia splendens oil collective effect.
Two, antipruritic experiment
Take mouse 50, it is male female fifty-fifty, be randomly divided into 4 groups, i.e., control group, example 1 group, 2 groups of embodiment, 1 group of comparative example and
2 groups of comparative example.Reagent of this experiment with physiological saline as a control group.
First day by mouse it is right after instep unhairing, and 1cm2 at the shaving of instep is uniformly abraded with coarse sandpaper.Second day small
It is cleaned respectively with control group, example 1 group, 2 groups of embodiment, 1 group of comparative example and 2 groups of comparative example at the surface of a wound of mouse instep, clearly
Histamine phosphate normal saline solution is dripped to the mouse instep surface of a wound after washing, it is water-soluble to be then incremented by histamine phosphate physiology salt every 3min
Liquid concentration.Its concentration is respectively 0.01%, 0.02%, 0.03%, 0.04% incremented by successively, and concentration increases by 0.01% every time, often
Secondary dripping quantity 0.05ml, until mouse later licks right metapedes.The total amount of computation organization's amine is itched valve as cause of the invention；With
Blank control group compares, and carries out group difference analysis, and itching-relieving action test result is shown in Table 3.
3 different product of table to histamine to mouse itch influence
| Group | Mouse quantity | Histamine causes the valve dosage/ug that itches |
| Example 1 group | 10 | 40.05±1.65 |
| 2 groups of embodiment | 10 | 42.78±7.51 |
| 1 group of comparative example | 10 | 18.79±1.65 |
| 2 groups of comparative example | 10 | 20.32±7.12 |
| Control group | 10 | 15.15±3.84 |
Studies have shown that histamine is a kind of important mediator that can cause pruitus.Mouse is pierced by antigen in normal circumstances
After swashing, skin lesion, pathology and immune etc. feature are consistent with mankind's dystopy skin lesion.It is above-mentioned the experimental results showed that, with the present invention
Histamine causes threshold values increase of itching after handmade soap cleaning, can effectively inhibit pruitus caused by histamine.
Claims (9)
1. a kind of mosquito-expelling and antipruritic handmade soap, it is parts by weight that raw material, which includes as follows,
4-12 parts of Asian puccoon, 140-160 parts of olive oil, 50-100 parts of palm oil, 50-100 parts of coconut oil, 50-100 parts of sesame oil,
40-75 parts of sodium hydroxide, 120-140 parts of water.
2. mosquito-expelling and antipruritic handmade soap according to claim 1, which is characterized in that raw material includes as follows, is parts by weight,
8-12 parts of Asian puccoon, 150-160 parts of olive oil, 60-75 parts of palm oil, 60-75 parts of coconut oil, 60-75 parts of sesame oil, hydrogen-oxygen
Change 4555 parts of sodium, 120-130 parts of water.
3. mosquito-expelling and antipruritic handmade soap according to claim 1, which is characterized in that raw material further includes honeysuckle, honeysuckle
Weight accounts for the 1-8% of olive oil weight.
4. mosquito-expelling and antipruritic handmade soap according to claim 3, which is characterized in that the weight of honeysuckle accounts for olive oil weight
2-5%。
5. mosquito-expelling and antipruritic handmade soap according to claim 1, which is characterized in that raw material further includes folium artemisiae argyi, the weight of folium artemisiae argyi
Account for the 1-8% of olive oil weight.
6. mosquito-expelling and antipruritic handmade soap according to claim 5, which is characterized in that the weight of folium artemisiae argyi accounts for the 1- of olive oil weight
3%。
7. mosquito-expelling and antipruritic handmade soap according to claim 1, which is characterized in that raw material further includes elsholtzia splendens oil, Haizhou
The weight content of elsholtzia oil is 8-20%.
8. mosquito-expelling and antipruritic handmade soap according to claim 7, which is characterized in that the weight content of elsholtzia splendens oil is 10-
14%。
9. a kind of preparation method of mosquito-expelling and antipruritic handmade soap, comprises the following steps that
(1) Asian puccoon, folium artemisiae argyi and honeysuckle are added in olive oil sealed soak 10~15 days, obtain mixture；
(2) mixture intense fire is heated to boiling, and mild fire heats 20min~30min under agitation, is separated by filtration removal medicine
Slag obtains filtrate；
(3) sodium hydroxide is poured into water by several times, it is stirring while adding, until melting completely, obtain buck；
(4) coconut oil, palm oil, sesame oil, elsholtzia splendens oil and the filtrate of step (2) are heated to 35-45 DEG C, must mixed
Oil；
(5) make buck temperature consistent with mixing oil temperature, buck is added in miscella, side edged persistently stirs 5-20min, obtains
The semi-finished product being thoroughly mixed；
(6) semi-finished product are poured into mold, after solidification, is demoulded to get mosquito-expelling and antipruritic handmade soap.
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