CN109045381A - Special pipeline pre-charging circulating device for ECMO and application thereof - Google Patents
Special pipeline pre-charging circulating device for ECMO and application thereof Download PDFInfo
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- CN109045381A CN109045381A CN201810795196.6A CN201810795196A CN109045381A CN 109045381 A CN109045381 A CN 109045381A CN 201810795196 A CN201810795196 A CN 201810795196A CN 109045381 A CN109045381 A CN 109045381A
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- preliminary filling
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- pipeline
- infusion bag
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- 238000002618 extracorporeal membrane oxygenation Methods 0.000 title claims abstract description 63
- 229920000669 heparin Polymers 0.000 claims abstract description 34
- 238000001802 infusion Methods 0.000 claims abstract description 33
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims abstract description 18
- 229960002897 heparin Drugs 0.000 claims abstract description 18
- 239000002775 capsule Substances 0.000 claims abstract description 17
- ZFGMDIBRIDKWMY-PASTXAENSA-N heparin Chemical compound CC(O)=N[C@@H]1[C@@H](O)[C@H](O)[C@@H](COS(O)(=O)=O)O[C@@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O[C@H]2[C@@H]([C@@H](OS(O)(=O)=O)[C@@H](O[C@@H]3[C@@H](OC(O)[C@H](OS(O)(=O)=O)[C@H]3O)C(O)=O)O[C@@H]2O)CS(O)(=O)=O)[C@H](O)[C@H]1O ZFGMDIBRIDKWMY-PASTXAENSA-N 0.000 claims abstract description 16
- 229960001008 heparin sodium Drugs 0.000 claims abstract description 16
- 230000000903 blocking effect Effects 0.000 claims abstract description 8
- 239000012530 fluid Substances 0.000 claims description 25
- 230000037452 priming Effects 0.000 claims description 21
- 210000004072 lung Anatomy 0.000 claims description 11
- 239000012528 membrane Substances 0.000 claims description 10
- 239000002504 physiological saline solution Substances 0.000 claims description 8
- 239000010409 thin film Substances 0.000 claims description 7
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 6
- 230000000694 effects Effects 0.000 claims description 6
- 239000001301 oxygen Substances 0.000 claims description 6
- 229910052760 oxygen Inorganic materials 0.000 claims description 6
- 238000000338 in vitro Methods 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 150000003839 salts Chemical class 0.000 claims description 3
- 238000006073 displacement reaction Methods 0.000 claims description 2
- 230000035479 physiological effects, processes and functions Effects 0.000 claims 1
- 239000007788 liquid Substances 0.000 abstract description 25
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract description 2
- 239000003814 drug Substances 0.000 abstract 1
- 238000002680 cardiopulmonary resuscitation Methods 0.000 description 13
- 238000011282 treatment Methods 0.000 description 9
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- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 230000002980 postoperative effect Effects 0.000 description 2
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- 238000007675 cardiac surgery Methods 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
Abstract
The invention discloses a pre-charging circulating device of a special pipeline for ECMO and application thereof, wherein the pre-charging circulating device comprises an infusion bag pre-charged with normal saline, two pre-charging liquid ports are arranged at the bottom of the infusion bag, a heparin capsule containing heparin sodium liquid medicine is arranged between the two pre-charging liquid ports, a channel is arranged between the heparin capsule and the infusion bag, a blocking film is arranged in the channel, and the distance between the two pre-charging liquid ports is 6-8 cm; the pre-filling circulating device can avoid liquid emptying caused by using a liquid transfer bag, shorten the pre-filling time of a pipeline and improve the first pre-filling success rate of the ECOM.
Description
Technical field
This application involves medical instruments field, especially a kind of high-effect ECMO pipe special preliminary filling circulator and its answer
With.
Background technique
Extracorporeal membrane oxygenation (extracorporeal membrane oxygenation, ECMO) is a breath cycle
Support technology, principle are to be drained to the venous blood of patient in vitro through centrifugal pump, the gas exchanges through artificial lung (oxygenator),
So that venous oxygen is combined into arterial blood, then is fed back to and plays cardiopulmonary substitution effect in vivo, as one of extracorporeal life support technology,
Early stage is applied to the patients such as extracorporal circulatory system off line difficulty, after cardiac surgery Low cardiac output syndrome, and application site is mainly performed the operation
Room；In recent years since ECMO effectively helps patient with severe symptoms to tide over fatal critical days, gain time significant effect for successive treatment,
Increase year by year in the application of intensive care unit (ICU) and emergency treatment, the support of the especially Severe acute disease patient of sudden cardiac arrest is controlled
It treats.
With the release of CPR guide and the training of reinforcement first-aid personnel, the spontaneous circulation of sudden cardiac arrest patient restores
Rate increases, and still has some patientss that cannot restore spontaneous circulation；Furthermore existing traditional CPR, even if spontaneous circulation
Restore, discharge survival rate, long-term surviving rate and Function outcome are also poor.Therefore, AHA " 2015 CPR in 2015
And emergency cardiovascular care guide " point out not react after carrying out traditional CPR for sudden cardiac arrest patient (adult or children), and body
When outer CPR (ECPR) energy Rapid Implementation, i.e., implementable ECPR, as sudden cardiac arrest patient application extracorporeal membrane oxygenation
(ECMO)。
Existing research shows that Extracorporeal cardiopulmonary resuscitation (ECPR) is relatively passed
The CPR of system can significantly improve survival rate, and JENNIE RYAN is in Extracorporeal Membrane Oxygenation
Be reported in the treatment of children in for Pediatric Cardiac Arrest point out traditional CPR survival rate 25%~27%,
The survival rate 40%~60% of ECPR, part body researches show that up to 72%-80%, the gorgeous equal CPR in vitro of domestic Wei Hong
Meta-analysis to human adult heart arrest victim's influence prognosis the result shows that: the spontaneous circulation of the patient of ECPR group and CPR group is extensive
Multiple rate is respectively 86.0% and 61.0%, and discharge survival rate is respectively 34.8% and 17.3%, and long-term surviving rate is respectively 27.0%
With 9.5%, Function outcome rate of good is respectively 21.0% and 7.4%, it was therefore concluded that is improving human adult heart arrest victim's
Spontaneous circulation recovery rate, discharge survival rate, long-term surviving rate and nervous function state aspect, ECPR all have more significant excellent
Gesture.
Successful CPR is not only to restore patient's spontaneous circulation, and final purpose is protection or as restores complete as possible
Brain function, therefore as far as possible shorten cerebral hypoxia ischemia time be to restore the best factor of brain function.Specific to
It is most important to need to shorten the operating time after implementing the decision of this technology, time and machine including setting pipe in the implementation of ECMO
Device starts the time successfully operated.Research is pointed out, ECMO treatment is determined and started through specialist, once patient sets pipe success,
Should be immediately connected to ECMO circulation line uplink supportive treatment, for this point, most of center usual used times in 10~20min,
Thus the importance for having prompted ECPR therapeutic time after sudden arrest of heart beat carries out ECMO during CPR, restricts in success factor
Most critical is timeliness, and making great efforts shortening Emergency care response time can effectively improve the success rate of recovery.
The implementation of ECMO is a complicated and fine technical process, and the main preparation including personnel's material, pipeline are pre-
It fills, the merging of arteriovenous pipeline, postoperative care etc..Pipeline preliminary filling needs rigorously to have as sport technique segment important in ECMO implementation
The care operation process of sequence, the domestic " ECMO write at present using teacher Huang Weiming that People's Health Publisher in 2014 publishes
Application manual " in ECMO pipeline method for pre-charging: the ECMO pipeline preliminary filling of rescue scene is a urgent and fine process, behaviour
Served as during work by 2 High qualification nurses, Sang Baozhen etc. in vitro membrane lung oxygen close art Plays care program research with
Report in practice: using standardization of care program, ECMO pipeline pre-charging time has 24.10 original ± 2.05min to foreshorten to
19.67±2.38min。
At present ECMO pipeline preliminary filling using conventional infusion bag (as shown in Fig. 1) infusion bag lower end set there are two port, one
For connecting pre- charge and exhaust pipe B syringe needle, one end is used for the heparin sodium aqua being added in priming fluid at end, and distance is about between two ports
2cm or so.When preliminary filling, 10mg heparin sodium is added into 1000ml infusion bag as required first, so that glutinous in heparin sodium aqua
Polysaccharide and the work material surface of extracorporeal membrane oxygenation carry out Covalent bonding together, make artificial material part simulation human vas endothelium function
Can, the generation of lactic acid is reduced, the biocompatibility of material is increased, the formation of thrombus is avoided and mitigates Postoperative inflammatory reaction.And show
Having heparin sodium aqua is that 2ml/ branch glass pacifies amber packaging, and medical staff needs to pacify amber first with iodophor disinfection and the glass broken into two with one's hands, sternly
0.2ml heparin is extracted under lattice asptic technique adds normal saline dilution to 2ml, using with needle injection by the heparin sodium of predetermined dose
Solution is added from the dosing port of infusion bag, and the concentration and dosage of medical fluid is effectively ensured, which will undoubtedly occupy a large amount of valuable
Rescue time.
Clinically pre- charge and exhaust pipe has AB two (attached drawing 3), connects liquid transfering bag on exhaust pipe A, under connect the three of circulation pipe
Pass (by centrifugation pump head distal end) is opened up, pre- charge and exhaust pipe B syringe needle is inserted into priming fluid sack, and other end connects the three-way cock of circulation pipe
(by being centrifuged pump head proximal end) is closed this two pre- charge and exhaust pipes with pipe clamp, need to adjust after booting zeroing flow knob to
2000r/h (flow > 1.0L/min), the preliminary filling under desired quick revolving speed or flow need operator in packed priming fluid
The pre- charge and exhaust pipe B of clamp, prevents emptying rate of liquid and shuts down when interior liquid will be finished, and pulls out priming fluid sack B pipe syringe needle, insertion
Another infusion port of liquid transfering bag forms circulation of the liquid in bag, such to operate emptying rate of liquid often and cause pipeline
And enter air in centrifugation pump head, lead to preliminary filling failure for the first time, and need repeat switch machine, pre-charging time caused to extend,
Seriously affect the machine supportive treatment time on the ECMO of patient.To improve preliminary filling success rate for the first time, pipe is carried out frequently with double cooperation
The operation of road preliminary filling, i.e. a people is responsible for the operation of pipeline preliminary filling exhaust, while another people is responsible for the packed preliminary filling liquid row of close observation
Air situation condition, it is necessary to shut down and adjust the socket of preliminary filling B pipe before emptying rate of liquid in time, assist clinician to carry out two at the same time
The indwelling of road pipeline.In the case where the especially late night care human resources of current emergency care shortage of resources lack, often
Only nursing staff is responsible for that preliminary filling and cooperation doctor's indwelling pipeline of ECMO pipeline etc. be complicated and fine operation skill simultaneously
Art, therefore how to implement one man operation, solution releases more human ltcs, cooperate other emergency treatments of ECMO treatment, and
And can effectively shorten pipeline pre-charging time, one preliminary filling success rate for the first time is improved, is as early as possible that CPR patient implements machine branch on ECMO
Hold treatment, it has also become using ECMO technology, improve salvage success rate technical problem urgently to be resolved.
Summary of the invention
In view of the above-mentioned problems, the present invention provides a kind of high-effect ECMO pipe special preliminary filling circulator, can avoid using
Emptying rate of liquid caused by liquid transfering bag shortens pipeline pre-charging time, and preliminary filling success rate, the present invention are realized in for the first time for raising
:
A kind of ECMO pipe special preliminary filling circulator, the infusion bag including preliminary filling physiological saline, there are two infusion bag bottom is set
Priming fluid port, respectively port A and port B are equipped between two priming fluid ports (i.e. between port A and port B) and contain liver
The heparin capsule of plain sodium medical fluid is equipped with a channel, is equipped with one of blocking thin film in channel between heparin capsule and infusion bag；It is described
The interior spacing (i.e. the interior spacing of port A and port B) of two priming fluid ports is 6-8cm.
Further, in ECMO pipe special preliminary filling circulator provided by the invention, preliminary filling in the infusion bag
0.9% physiological saline 1000m, the heparin sodium containing 10mg in heparin capsule, after the two mixing, will obtain mass fraction is 10mg
Heparin sodium priming fluid.
The present invention additionally provides the application of the ECMO pipe special preliminary filling circulator, conventional extracorporeal membrane oxygenation simultaneously
Emptying closed circuit is concatenated by passing sequentially through pipeline between centrifugal pump, external membrane lung, connector, and pipeline is equipped with the end a and b
End, specific step is as follows for the application:
1) end a of pipeline and the end b are passed through into fittings, it is ensured that pipeline forms closed circuit；The ECMO pipe special is pre-
It fills in one section of pipeline that the priming fluid port of circulator is respectively connected between connector and centrifugal pump, pipe grippers is then blocked two
Pipeline between access point makes ECMO pipe special preliminary filling circulator become the bypass branch of this section of pipeline of substitution；
2) heparin capsule is squeezed, the heparin in capsule breaks through the physiological saline that blocking thin film enters infusion bag under the effect of the pressure
Middle formation buffer；
3) start centrifugal pump, making the buffer in ECMO pipe special preliminary filling circulator, membrane lung oxygen closes emptying closed tube in vitro
It is recycled in road, by the air displacement in closed circuit into ECMO pipe special preliminary filling circulator；
4) after the air in conventional extracorporeal membrane oxygenation emptying closed circuit is all replaced, stop centrifugal pump, this
When connector is disconnected rapidly, after the end pipeline a and the end b to be respectively connected to arterial cannulation and the venous cannula position of human body, off-tube
Road pincers, and be completely separated with ECMO pipe special preliminary filling circulator.
Compared with prior art, the present invention has following technical effect that
1, transfusion label is affixed directly in infusion outer packing, is conveniently taken；Transfusion label content is primarily directed to pipeline preliminary filling
Design, do not need clinical nursing staff write or write when omit important content, can the effectively save time, meet safety nursing
Quality.
2, there are two priming fluid ports for design, and preliminary filling pipe A, B are connected simultaneously, avoided using caused by liquid transfering bag
The possibility of emptying rate of liquid improves preliminary filling success rate for the first time, shortens pipeline pre-charging time, improves working efficiency, avoids using liquid
Repeat switch machine when transfering bag can safely and efficiently implement single preliminary filling in the state that operator is in short supply.
3, the distance between the port A of circulation fluid bag lower end and port B internal diameter are 6-8cm, in use, one end (port A)
For air inlet (being discharged into the air in circulation line, connect the preliminary filling interface tube A on circulation line), one end (port B) is infusion
Mouth (the preliminary filling interface tube B on connection circulation line), distance between the two can be effectively prevented air and enter circulation with liquid
In pipeline.
4, the heparin sodium 10mg that preliminary filling needs dosage is placed at place, and it is raw to enter preliminary filling for implementable extruding heparin liquid when needing to add
It manages in salt water, avoids dosing, save the time, prevent needle and stab generation.
Detailed description of the invention
Fig. 1 is existing infusion bag structural schematic diagram；
Fig. 2 is ECMO pipe special preliminary filling circulator structural schematic diagram；
Fig. 3 is that existing ECMO pipe special preliminary filling recycles schematic diagram；
Fig. 4 is that the application ECMO pipe special preliminary filling recycles schematic diagram；
In figure: 1, infusion bag；2, port A；3, port B；4, heparin capsule；5, label；6, diaphragm is blocked；7, centrifugal pump；8, body
Outer membrane lung；9, connector；10, pipeline；11, exhaust pipe A；12, pre- charge and exhaust pipe B；13, pipe grippers.
Specific embodiment
1 ECMO pipe special preliminary filling circulator of embodiment
ECMO pipe special preliminary filling circulator structure provided in this embodiment is as shown in Figure 2: a kind of ECMO pipe special preliminary filling
Circulator, the infusion bag 1 including preliminary filling physiological saline, infusion bag bottom are set there are two priming fluid port, respectively port A2
With port B3, the heparin capsule 4 of the medical fluid containing heparin sodium is equipped between port A2 and port B3, between heparin capsule 4 and infusion bag 1
Equipped with a channel, one of blocking thin film 6 is equipped in channel；Interior spacing between port A2 and port B3 is 8cm(specific implementation
In, which can control within the scope of 6-8cm).
In the present embodiment, the physiological saline 1000m that preliminary filling mass fraction is 0.9% in infusion bag 1 contains in heparin capsule 4
There is the heparin sodium of 10mg, after the two mixing, the heparin sodium priming fluid that mass fraction is 10mg will be obtained in infusion bag 1.
In the present embodiment, the material of blocking thin film 6 is that PVC material also can be used in the prior art in specific implementation
Block the other materials of diaphragm.
2 ECMO pipe special preliminary filling circulator application of embodiment
Conventional extracorporeal membrane oxygenation emptying closed circuit is by passing sequentially through pipeline between centrifugal pump 7, external membrane lung 8, connector 9
10 concatenate, and pipeline 10 is equipped with the end a and the end b, set that there are two threeways on pipeline 10, are arranged respectively by exhaust pipe A11 and preliminary filling
Tracheae B12 is connected with the port A2 and port B3 of ECMO pipe special preliminary filling circulator.
The ECMO pipe special preliminary filling circulator priming procedure is as follows:
1, finger pressure heparin capsule 4, the heparin sodium in capsule break through the life that blocking thin film 6 enters infusion bag 1 under the effect of the pressure
Priming fluid is formed in reason salt water；
2, the end a of pipeline 10 is connected to the end b by connector 9, it is ensured that pipeline 10 forms closed circuit；By exhaust pipe A11, hang defeated
It on liquid frame, is inserted into 1 port A2 of infusion bag, the three-way cock of circulation pipe is connect under exhaust pipe A11 (by centrifugation pump head distal end);It takes out another
One pre- charge and exhaust pipe B12 is inserted into 1 port B3 of infusion bag, and other end connects the three-way cock (by being centrifuged pump head proximal end) of circulation pipe,
Exhaust pipe A11 and pre- charge and exhaust pipe B12 is closed with pipe clamp, circulation line 13 clamp of pipe grippers between two pipes；
2, the pipe clamp of pre- charge and exhaust pipe B12 is opened, the three-way cock for connecting circulation pipe is opened, the preliminary filling liquid stream in infusion bag 1
Through centrifugal pump 7 and external membrane lung 8, the air in centrifugal pump 7 and external membrane lung 8 is drained, centrifugation pump head rate of discharge connector is smeared
Centrifugation pump head is placed in pump slot and is fixed by couplant；Open the centrifugation pump head pre- charge and exhaust pipe A11 in distal end three-way cock and
Pipe clamp opens centrifugal pump 7, rotation flow button, and revolving speed is gradually increased to 2000r/min(flow > 1.0L/min), checks complete
After portion's pipeline air exhaust water is clean, open the pipe grippers of the circulation line between two three-way cocks, (with the flow of 3~4L/min) again
Pipeline (especially circulating line packet) bubble-free is reaffirmed in exhaust, observes machine run situation.
3, the priming fluid in infusion bag 1 flows through entire circulation line, the air in pipeline 10 is discharged by port A2 defeated
In liquid bag 1, since physiological saline volume (1000ml) is much higher than volume of air (about 500ml) in pipeline in infusion bag 1, therefore preliminary filling
Liquid is in pipeline 10 and ECMO pipe special preliminary filling circulator internal circulation flow, without pipeline evacuation situation.
4, after the air in conventional extracorporeal membrane oxygenation emptying closed circuit is all replaced, using sterile tube
The end a and the end b on road clamp stopped pipe road 10, at this time rapidly disconnect connector 9, and the end a of pipeline 10 and the end b are respectively connected to human body
After arterial cannulation and venous cannula position, sterile pipes pincers are disconnected, are recycled so that the blood of patient closes in pipeline in ECMO oxygen, it
It is completely separated afterwards with ECMO pipe special preliminary filling circulator.
Those skilled in the art can understand that unless otherwise defined, all terms used herein (including skill
Art term and scientific term) there is meaning identical with the general understanding of those of ordinary skill in fields of the present invention.Also
It should be understood that those terms such as defined in the general dictionary should be understood that have in the context of the prior art
The consistent meaning of meaning will not be explained in an idealized or overly formal meaning and unless defined as here.
Above-described specific embodiment has carried out further the purpose of the present invention, technical scheme and beneficial effects
It is described in detail, it should be understood that being not limited to this hair the foregoing is merely a specific embodiment of the invention
Bright, all within the spirits and principles of the present invention, any modification, equivalent substitution, improvement and etc. done should be included in the present invention
Protection scope within.
Claims (4)
1. a kind of ECMO pipe special preliminary filling circulator, the infusion bag including preliminary filling physiological saline, it is characterised in that: infusion bag
Bottom is set there are two priming fluid port, and the heparin capsule of the medical fluid containing heparin sodium, heparin capsule are equipped between two priming fluid ports
It is equipped with a channel between infusion bag, is equipped with one of blocking thin film in channel.
2. ECMO pipe special preliminary filling circulator according to claim 1, it is characterised in that: two priming fluid ports
Spacing is 6-8cm.
3. ECMO pipe special preliminary filling circulator according to claim 1 or 2, it is characterised in that: it is characterized by: institute
The preliminary filling physiological saline of 1000ml in the infusion bag stated contains heparin sodium 10mg in heparin capsule.
4. a kind of application of ECMO pipe special preliminary filling circulator as claimed in claim 3, it is characterised in that: conventional is external
Membrane lung oxygen, which closes emptying closed circuit, to be concatenated by passing sequentially through pipeline between centrifugal pump, external membrane lung, connector, using specific
Steps are as follows:
1) one be respectively connected to the priming fluid port of the ECMO pipe special preliminary filling circulator between connector and centrifugal pump
In Duan Guanlu, pipe grippers are then blocked into the pipeline between two access points, becomes ECMO pipe special preliminary filling circulator and replaces
For the bypass branch of this section of pipeline；
2) heparin capsule is squeezed, heparin sodium stoste breaks through 0.9% physiology that blocking thin film enters infusion bag under the effect of the pressure
Priming fluid is formed in salt water；
3) start centrifugal pump, making the priming fluid in ECMO pipe special preliminary filling circulator, membrane lung oxygen closes emptying closed tube in vitro
It is recycled in road, by the air displacement in closed circuit into ECMO pipe special preliminary filling circulator；
4) after the air in conventional extracorporeal membrane oxygenation emptying closed circuit is all replaced, stop centrifugal pump, this
When connector is disconnected rapidly, after being respectively connected to arterial cannulation and the venous cannula position of human body, disconnect pipe grippers, and it is special with ECMO
It is completely separated with pipeline preliminary filling circulator.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810795196.6A CN109045381A (en) | 2018-07-19 | 2018-07-19 | Special pipeline pre-charging circulating device for ECMO and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810795196.6A CN109045381A (en) | 2018-07-19 | 2018-07-19 | Special pipeline pre-charging circulating device for ECMO and application thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109045381A true CN109045381A (en) | 2018-12-21 |
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|---|---|---|---|
| CN201810795196.6A Pending CN109045381A (en) | 2018-07-19 | 2018-07-19 | Special pipeline pre-charging circulating device for ECMO and application thereof |
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Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| CN209075643U (en) * | 2018-07-19 | 2019-07-09 | 江苏省人民医院（南京医科大学第一附属医院） | Special pipeline pre-filling circulating device for ECMO |
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| US5391142A (en) * | 1992-07-29 | 1995-02-21 | Organetics, Ltd. | Apparatus and method for the extracorporeal treatment of the blood of a patient having a medical condition |
| CN2640478Y (en) * | 2003-07-14 | 2004-09-15 | 王孝文 | Portable external circulation film lung pump |
| CN201073456Y (en) * | 2007-07-06 | 2008-06-18 | 段大为 | Vitro membrane oxygenation pipeline quick pre-charging bag |
| KR20120122623A (en) * | 2011-04-29 | 2012-11-07 | 대한약품공업 주식회사 | A port assembly and an infusion bag for preventing drug misuse |
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