CN107308513B - A kind of ECMO membrane lung flushing droplet collection device - Google Patents

A kind of ECMO membrane lung flushing droplet collection device Download PDF

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Publication number
CN107308513B
CN107308513B CN201710441581.6A CN201710441581A CN107308513B CN 107308513 B CN107308513 B CN 107308513B CN 201710441581 A CN201710441581 A CN 201710441581A CN 107308513 B CN107308513 B CN 107308513B
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ecmo
drop
membrane lung
accommodating cavity
collection device
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CN107308513A (en
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赵海萌
孙兵
王淑芹
李海超
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Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital University of Medicine Sciences
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Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital University of Medicine Sciences
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1698Blood oxygenators with or without heat-exchangers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601Control or regulation
    • A61M1/1619Sampled collection of used dialysate, i.e. obviating the need for recovery of whole dialysate quantity for post-dialysis analysis

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  • Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

The present invention provides a kind of ECMO operating method that droplet collection device is rinsed with membrane lung, comprising steps of 1) pipeline prepares;2) pipe puncture is set;3) it is intubated;4) controller of control device and ECMO that membrane lung rinses droplet collection device is connected, is rushed and pressed from both sides in advance the prerun operation of closed loop;5) ECMO system is transferred to operation by bed;6) centrifugal pump is opened, oxygen is opened, checks the working condition of droplet collection device, fixed catheter in blood vessel is tied in patient skin, is covered after fixed with aseptic dressing;7) ECMO is terminated, hemostasis operation is carried out after tube drawing, recovery vein is unimpeded, and droplet collection device is removed and is sent to corresponding pathological analysis room and is analyzed.A kind of collection device of ECMO membrane lung flushing drop is also provided, both the safety and sanitation of ECMO working environment had been guaranteed, drop can also be efficiently used and carry out microbemia detection as assay specimen, provide valuable data and reference for the evaluation of ECMO operation conditions and care environments.

Description

A kind of ECMO membrane lung flushing droplet collection device
Technical field
The present invention relates to medical instruments field, especially a kind of ECMO membrane lung rinses droplet collection device.
Background technique
Extracorporeal membrane oxygenation (extracorporeal membrane oxygenation, ECMO), is the one of extracorporal circulatory system Kind, ECMO can breathe Refractory Severe and/or the critical patient of circulation function failure carries out effective breath cycle support.Its Principle is to carry out gas through oxygenator (artificial lung) for outside intracorporal blood lead body by pump (it acts on similar artificial heart) Oxygen synthesis arterial blood injection patient's central aortic or vein are exchanged, part cardiopulmonary substitution effect is played.The basic structure packet of ECMO Include endovascular prosthesis pipe, connecting tube, kinetic pump (artificial heart), oxygenator (artificial lung), oxygen supplying tube, monitoring system.Wherein move Power pump and oxygenator are two the most key components.Kinetic pump is otherwise known as artificial heart, and effect is to form power to drive A Fang Liudong of the blood to pipeline, the function of similar heart, the kinetic pump that clinically there are mainly of two types: roller pump and centrifugation Pump.Since roller pump is not easily shifted, difficult management, in the preferred centrifugal pump of first aid profession as kinetic pump, advantage is that installation moves Dynamic convenient, convenient for management, Blood damage is small, has swabbing action in reasonable range of negative pressure, caused by can solving certain reasons Low discharge problem, centrifugal pump of new generation also easily manipulate children's low discharge.Oxygenator is otherwise known as artificial lung, function be by Non-oxygen conjunction blood oxygen synthesizes oxygenated blood, and ECMO oxygenator has silica gel membrane type and two kinds of hollow fiber type, silica gel membrane type membrane lung compatibility Good, rare plasma leakage, blood constituent destroys small, suitable long-time auxiliary, such as supports cardio-pulmonary function waits transplant, infect institute Respiratory failure is caused, the disadvantage is that exhaust problem, expensive.Hollow fiber type membrane lung is easily vented, and visible blood plasma seeps within 2-3 days Leakage, blood constituent destruction is relatively large, but is first aid set packet since simple installation is still preferred, if desired, can be in one after the stable state of an illness Suitable oxygenator is replaced in two days.
According to therapeutic modality and purpose, ECMO mainly has veno-arterial ECMO (VA-ECMO) and vein-vein ECMO (VV-ECMO) two kinds, VV-ECMO is suitable for only needing the patient of Breathing Suppotion, and VA-ECMO is breathed and recycled branch simultaneously It holds.
Referring to attached drawing 1, veno-arterial ECMO (VA-ECMO) sets pipe by vena cave (femoral vein or jugular vein), manually Pump leads to body circulation blood flow in vitro, returns in vivo through arteria carotis or femoral catheter again after the conjunction of membrane lung oxygen, is equivalent to membrane lung In parallel with Patients with Lung progress, this mode is identical as traditional extracorporal circulatory system.
Referring to attached drawing 2, vein-vein ECMO (VV-ECMO), ECMO draw blood end (mostly femoral vein) and blood back end (mostly Jugular vein) it is respectively positioned in vena cave, it is equivalent to artificial membrane lung and connects with Patients with Lung, so that patient's arterial oxygen content obtains To improve, although vein-vein ECMO (VV-ECMO) cannot provide circulatory support, due to required positive airway pressure in its operation The increase that the reduction of support pressure and coronal arterial oxygen supply, the heart function of patient can also be improved to a certain extent.
Show oxygen for airflow portion in attached drawing 1-2, it is generally the case that pure oxygen or titanium dioxide of the oxygen for air-flow for 100% The mixed air of carbon and oxygen, containing 5% carbon dioxide and 95% oxygen, conventional arrangement oxygen is for air flow rate and blood flow It is equal, i.e., 1: 1, the removing of carbon dioxide can be increased for air flow rate by increasing oxygen, but is taken a group photo to oxygen and rung very little, if ECMO is only For removing carbon dioxide, lesser membrane lung can be selected, blood flow can reduce, and oxygen often selects oxygen, air-flow for air-flow It is usually 10: 1 with the ratio between blood flow.Vapor can be formed in long-term use process can be aggregated in membrane lung, and interruption improves oxygen and supplies The flow flush membrane lung of air-flow avoids vapor from being aggregated membrane lung function reduction caused by forming " pulmonary edema ".Even in addition, solid Body silica gel and solid hollow fiber membrane lung, it is also possible to because of lesser damaged formation gas embolism, it is therefore necessary to maintain in membrane lung The pressure of blood flow side is higher than air-flow side, in oxygen for installation pressure relief valve or pressure servo adjusting controller on gas flow tube road, or Person keeps the level height of membrane lung to be lower than patient, can pass the gas through membrane lung and enters the risk of blood flow and is preferably minimized.
It is found in the practice operation used by ECMO, two outlets of the meeting below membrane lung during rinsing membrane lung There is drop in (one is relatively large in diameter, and a diameter is smaller), and common practice is that the drop is directly dripped and evaporated on the ground, Without will do it any medical response.It can not determine whether these drops contain pathogenic microorganisms, cause environmental pollution, or even disease The propagation of opportunistic pathogen.This random disposal options to drop, it is both unhygienic, drop can not be effectively utilized, is as ECMO The no monitoring index to break down provides valuable data and reference for the ECMO operation and maintenance of next step.
Summary of the invention
The basic thought that the technical scheme adopted by the invention to solve the technical problem is: in front of ECMO operation, by one A collection device with specific structure is connect with membrane lung, in operational process, time which works according to ECMO into The regular opening and closing of row collect quantitative liquid and carry out subsequent Etiology analysis.
In order to overcome the above problem of the existing technology,
In order to overcome the above problem of the existing technology, the present invention provides a kind of collection dress of ECMO membrane lung flushing drop It sets, comprising: membrane lung, apopore and side opening on membrane lung, pipeline, drop accommodating cavity, the lid of drop accommodating cavity, movable cover button are carved Item is spent, the pipeline is connect with the membrane lung by cross bar, places the drop accommodating cavity, the appearance in the lower section of the membrane lung Setting chamber can receive the drop of the apopore and side opening outflow, and the drop accommodating cavity passes through attachment device and the cross Bar connection, when cap closure, are able to maintain the drop accommodating cavity and are completely closed, and the movable cover button is located at the lid One or both sides, for opening the lid manually or automatically when ECMO is run with collection membrane lung lavage drop, the lid Sub that sealing strip is filled between the drop accommodating cavity, the lid is to fold fan, the maximum volume of the drop accommodating cavity For 20ml, the minimum interval of droplet transfer is 8 hours, and the scale strip is located in the drop accommodating cavity one side wall, uses In the volume of metering drop to carry out subsequent drop ingredient and the analysis of patient's pathogenicity, the movable cover button is by metal material system At control device is connect by a magnetic push rod with movable cover button, the control device and the real-time communication of ECMO controller, when described When ECMO starts, the control device issues starting control signal, and the magnetism push rod pushes the movable cover button to open the lid Son, when the ECMO is out of service, the control device, which issues, stops control signal, and the magnetism push rod pulls institute outward It states movable cover button and is closed the lid.
Preferably, the attachment device is hook, rivets or is bonded, and under riveting method, a gold is covered on the cross bar Belong to circle, the drop accommodating cavity is made of metal material, after metal thin bar welding, then with the quoit riveting on cross bar It connects, under bonding way, is connect using adhesive of medical with the drop accommodating cavity of the other materials in addition to metal.
Preferably, the drop accommodating cavity is two, respectively apopore and side opening described in face.
This rinses the ECMO operating method of droplet collection device with membrane lung, includes the following steps: 1) pipeline preparation, according to After the state of an illness determines ECMO treatment, all intubation heparin salines flushings are spare, according to ECMO routine, need to give before merging casing The aggressive dosage liver rope of 55-100U/kg, even if patient's blood coagulation disorders and just in bleeding;2) pipe puncture is set, in the following manner Puncture and intubation is carried out, sets pipe firstly, cutting, then, couple punctures, and seal wire is positioned and expanded step by step, is finally used in combination It cuts exposed and Semi-Seldinger casing implantation or Thorax operration and casing is directly placed in atrium dextrum and aorta;3) it inserts It manages, after injecting heparin, will be intubated and enter vein by leading core direct-view underthrust, intubation ostium arteriosum must make to enter towards tricuspid valve intracorporal Arterial blood largely enters tricuspid valve, reduces recycling, fixed intubation of sewing up the incision;4) membrane lung is rinsed into droplet collection device The prerun operation of closed loop is rushed and is pressed from both sides in advance in the connection of the controller of control device and ECMO;5) ECMO system is transferred to Bed is other, powers on and oxygen, connection shift to an earlier date stable operation in the water tank of 37 DEG C of water temperatures, by support staff's drawing ECMO system Blood, blood back pipeline give puncture procedure person, by operator will draw blood vessel road and blood back pipeline respectively and draw blood, blood back conduit connects It connects;6) centrifugal pump is opened, oxygen is opened, checks the working condition of droplet collection device, tie fixed catheter in blood vessel in patient Skin is covered after fixed with aseptic dressing;7) it is assisted after a period of time, when overall merit patient can be detached from ECMO, ECMO controller is issued into termination signal, checks whether droplet collection device stops corresponding collection work, the laggard whereabouts blood of tube drawing Operation, recovery vein is unimpeded, and droplet collection device is removed and is sent to corresponding Etiology analysis room and is analyzed.
Step (2) cuts casing implantation using jugular vein for newborn and young children, for two years old with Using in the one vein ECMO of vein of percutaneous puncture casing implantation, direct heart canula implantation is used for by upper children or adult It cannot be detached from the patient of extracorporal circulatory system (CPB) in operating room, CPB casing can be used, one transvenous approach of medium sized vein can make Access is established with double-cavity puncture conduit, or establishes access in two different retaining venipunctures.
Step (2) jugular vein cuts the concrete operations of casing implantation are as follows: described sleeve pipe merging usually in ICU into Row, carry out sufficient Aseptic sterilisation, and carried out by the Zhi Guan group of operating room, give patient's deep sedation and/or anesthesia and Flesh pine, inhibits autonomous respiration, to avoid air embolism, the anesthesia of row local skin cuts exposure blood vessel, not press blood directly Pipe administers locally to lidocaine or papervine to reduce vasopasm, in casing merging point to avoid angiogenesis spasm Above and below respectively by two root knot bindings bypass blood vessel, after vein gives heparin 50-100U/kg, ligation blood vessel distal end, blood vessel Proximal end is closed with blood vessel clamp, is placed in casing after cutting blood vessel, causes casing merging difficult if blood vessel is very small, or if blood Spasm occurs for pipe, and firm reinforce is given at the proximal edge of blood vessel and is sutured, blood vessel is surrounded on casing, and is tied It pricks, conduit often passes through one " sheath " ligation in the blood vessels, in order to later period Lumen catheter.
Step (2) the percutaneous puncture casing implantation concrete operations are as follows: casing merging usually carries out in work ICU, into The stringent Aseptic sterilisation of row prepares, first placement Conventional compact blood vessel inner sleeve, by pumpback blood and measures endovascular blood pressure It is intravascular to confirm that conduit is located at, after sufficient Aseptic sterilisation processing, seal wire will be sent by puncture cannula, takes out to puncture and lead Pipe expands skin using skin device is expanded step by step, and the expander finally used is equivalent to the tube core of casing to be placed in, saturating using ultrasound and fluorescence The heparin of aggressive dosage can be given at any time after the merging of leading silk depending on auxiliary casing positioning.
The Semi-Seldinger concrete operations of step (2) are as follows: carried out in ICU, patient is anesthetized, and in aseptic condition A piece small-sized venous infusion catheter (20G) is penetrated skin and penetration rate of blood through notch distal end by lower progress, exposure blood vessel after incision Pipe, pumpback have blood stream go out confirm puncture tube be located at it is intravascular, hereafter give heparin, set thereafter through the venous infusion catheter Enter large size seal wire, use expander step by step, then wound skin is covered on casing and is stitched by the final ECMO casing that is placed in It closes, seems the percutaneous puncture catheter of standard in appearance.
The resistance of blood flow of the intubation of step (3) medium vessels approach is directly proportional to the length of pipeline, and four times with radius Side is inversely proportional, and the internal diameter of the intubation determines resistance of blood flow, and side opening and tip attenuate and influence resistance of blood flow, and resistance of blood flow meeting As the flow rate increases and increases.
The mode of A. blood vessel approach is divided into one artery of vein (VA) approach in step (3), one vein of vein (VV) approach with And mono- arterial-venous approach of AV, wherein the vein one artery (VA) approach is suitable for heart support and Breathing Suppotion, it is described quiet One vein of arteries and veins (VV) approach does not provide haemodynamics support, is used for Breathing Suppotion, and the mono- arterial-venous approach of AV is only applied When requiring lower to blood flow.
Using the device of the invention, it is connect by a collection device with specific structure with membrane lung, is worked according to ECMO Time carry out regular opening and closing, collect quantitative liquid and carry out subsequent pathogenicity analysis, operate both guaranteed in this way The safety and sanitation of ECMO working environment guarantee patient and other patients will not infect with ward, both guaranteed ECMO working environment Safety and sanitation, can also efficiently use drop as assay specimen carry out microbemia detection, for ECMO operation conditions indicate with And patient status instruction provides valuable data and reference.
The brief description of accompanying drawing
Attached drawing 1 is veno-arterial ECMO (VA-ECMO) schematic diagram of the prior art.
Attached drawing 2 is vein-vein ECMO (VV-ECMO) schematic diagram of the prior art.
Attached drawing 3 is the ECMO flow chart that according to the embodiment of the present invention there is membrane lung to rinse droplet collection device.
Attached drawing 4 is the collection device structural schematic diagram that drop is rinsed according to the ECMO membrane lung of the embodiment of the present invention.
Specific embodiment
Specific embodiment of the present utility model is described in detail with reference to the accompanying drawing, but is not intended to limit this reality With novel protection scope.
For attached Fig. 1 and 2 explanation referring to background technology part.
Referring to attached drawing 3, installed additional the ECMO that the membrane lung rinses droplet collection device key points for operation include: 1) pipeline it is quasi- Standby, after determining ECMO treatment according to the state of an illness, all intubation heparin salines flushings are spare, according to ECMO routine, are placed in front of casing The aggressive dosage liver rope of 55-100U/kg need to be given, even if patient's blood coagulation disorders and just in bleeding;2) set pipe puncture, by with Under type carries out puncture and intubation, sets pipe firstly, cutting, and then, couple punctures, and seal wire is positioned and expanded step by step, finally joins It closes and casing is directly placed in atrium dextrum and active with Semi-Seldinger casing implantation or Thorax operration using incision is exposed Arteries and veins;3) be intubated, after injecting heparin, look at intubation straight underthrust by leading core and enter vein, intubation ostium arteriosum must make towards tricuspid valve into Enter intracorporal arterial blood and largely enter tricuspid valve, reduces recycling, fixed intubation of sewing up the incision;4) membrane lung drop is rinsed to receive The control device of acquisition means and the controller of ECMO connect, and are rushed and pressed from both sides in advance the prerun operation of closed loop;5) by ECMO system System is transferred to by bed, is powered on and oxygen, and connection shifts to an earlier date stable operation in the water tank of 37 DEG C of water temperatures, by support staff by ECMO System draw blood, the blood back pipeline person that gives puncture procedure, blood vessel road and blood back pipeline will be drawn respectively by operator and draw blood, blood back Conduit connection;6) centrifugal pump is opened, oxygen is opened, checks the working condition of droplet collection device, tie fixed catheter in blood vessel In patient skin, covered after fixed with aseptic dressing;7) it is assisted after a period of time, overall merit patient can be detached from When ECMO, ECMO controller is issued into termination signal, checks whether droplet collection device stops corresponding collection work, tube drawing is laggard Row hemostasis operation, recovery vein is unimpeded, and droplet collection device is removed and is sent to corresponding Etiology analysis room and is analyzed.
Wherein, the part of several keys is referred in the key points for operation, comprising:
One, the mode of blood vessel approach, is divided into:
1. one artery of vein (VA) approach (is applied to heart to support, be also applied for Breathing Suppotion);
2. one vein of vein (VV) approach (does not provide haemodynamics support, is mainly used for Breathing Suppotion, because of which It can avoid damage main artery, and can avoid that Thrombosis occurs);
Mono- arterial-venous approach of 3.AV (when being only applied to require lower to blood flow, especially for removing CO2)
Two, it is intubated
" intubation (cannula) " word is exclusively used in indicating to be inserted directly into the conduit merging that blood vessel carries out ECMO, to be different from Conduit in every other device.The resistance of blood flow of blood vessel approach intubation is directly proportional to the length of pipeline, the biquadratic with radius It is inversely proportional.Therefore, the internal diameter of intubation is the main factor for determining resistance of blood flow.Other factors such as side opening and tip attenuate Resistance of blood flow can be influenced, and resistance of blood flow can as the flow rate increases and increases.Therefore, every set is familiar with before intubation to lead The characteristics of pipe.
Three, centesis
(1) piercing method
It can carry out in the following manner puncture and intubation: 1) cut and set pipe;2) couple puncture, seal wire positioning and step by step It expands (Semi-Seldinger technology);3) exposed incision and Semi-Seldinger casing implantation is used in combination or 4) opens Chest is postoperative to be directly placed in atrium dextrum and aorta for casing.In newborn and young children, typically required row jugular vein Cut casing implantation.Percutaneous puncture casing implantation is usually used in two years old or more children and adult one vein ECMO of vein In.Direct heart canula implantation is used to be detached from the patient of CPB (extracorporal circulatory system) in situations in the surgery room, can be covered using CPB Pipe.
One transvenous approach of vein can be used double-cavity puncture conduit and establish access, or set in two different venipunctures Pipe establishes access.
(2) puncture and intubation technology
It needs to give aggressive dosage liver rope (usual 55-100U/kg) before merging casing, even if patient's blood coagulation disorders and just In bleeding.
1, directly cut casing implantation: casing merging carries out usually in ICU, should carry out sufficient Aseptic sterilisation, and It should be carried out by the Zhi Guan group of operating room.It is necessary to give patient's deep sedation/anesthesia and flesh pine, inhibit autonomous respiration, To avoid air embolism.The anesthesia of row local skin.Cut exposure blood vessel.Try not directly to press blood vessel to avoid blood vessel hair Raw spasm.Vasopasm can be reduced by administering locally to lidocaine or papervine.Above and below casing merging point respectively Two root knot bindings are bypassed into blood vessel.Vein gives heparin (50-100U/kg)) after, ligation blood vessel distal end.Blood vessel proximal end blood vessel Clamp closes.Blood vessel is cut, casing is placed in.If blood vessel is very small, if casing merging is difficult, or if angiogenesis convulsion It is very useful to give firm reinforcing suture at the proximal edge of blood vessel for contraction.Blood vessel is surrounded on casing, and is tied It pricks, conduit often passes through one " sheath " ligation in the blood vessels, in order to later period Lumen catheter.In femoral artery puncture, use is non- The method of intubation (the semi-Seldinger puncture and intubation method that see below) of ligation can ensure that sufficient blood flow through periphery of spigot Arterial distal is flowed to, to ensure the perfusion of remote organization.
2, percutaneous casing implantation: casing merging usually carries out in work ICU, should carry out stringent Aseptic sterilisation and prepare, It need not be completed to set pipe by the Zhi Guan group of operating room but should done some preparations, when complication occurs for percutaneous puncture catheter, then It needs medical surgery team to carry out angitomy and sets pipe.Conventional compact blood vessel inner sleeve is placed first, this is often safest way.Pass through It is intravascular that pumpback blood and the endovascular blood pressure of measurement can confirm that conduit is located at.After sufficient Aseptic sterilisation processing, it will pass through Puncture cannula is sent into seal wire, takes out and punctures conduit, expands skin step by step using skin device is expanded.The expander finally used is equivalent to wait be placed in The tube core of casing.Under conditions of using existing equipment, percutaneous puncture casing implantation needs two people's operations: a people is by expander Expander is covered on seal wire and delivers, another people presses blood vessel during replacing expander to prevent bleeding.Work as use Seldinger technology punctures, and when using large size casing and expander, is both needed to check seal wire after each expansion, this is very heavy It wants.It should be extracted out when seal wire is twisted together or is bent and more renew seal wire.Facilitate casing positioning using ultrasound and fluoroscopy.Work as master After seal wire merging, the heparin of aggressive dosage can be given at any time.
3, Semi-Seldinger technology: the technology can carry out in ICU, and patient needs to anaesthetize, and must be in aseptic condition Lower progress.A piece small-sized venous infusion catheter (20G) is penetrated skin and penetration rate of blood through notch distal end by exposure blood vessel after incision Pipe.Pumpback have blood stream go out confirm puncture tube be located at it is intravascular, hereafter give heparin.Hereafter it can be placed in by this root conduit big Number seal wire.Expander is used step by step, it is final to be placed in ECMO casing.Hereafter, wound skin is covered on casing and is sutured, outside The percutaneous puncture catheter of standard is seemed in sight.The advantage of the relatively simple percutaneous puncture catheter of this technology is that its speed is fast, can With the pipe diameter size of accurate judgement blood vessel, and can be with flexible choice mode of operation.
Referring to attached drawing 4, membrane lung rinses the collection device of drop in a kind of ECMO, comprising: membrane lung (1), going out on membrane lung (1) Water hole (1-1) and side opening (1-2), pipeline (2), drop accommodating cavity (5), the lid (4) and movable cover button of drop accommodating cavity (5) (5), pipeline (2) is connect with membrane lung (1) by cross bar, places drop accommodating cavity (5) in the lower section of membrane lung (1), accommodating cavity (5) can To receive the drop of apopore (1-1) and side opening (1-2) outflow, drop accommodating cavity (5) is connect by attachment device with cross bar, is covered It is able to maintain drop accommodating cavity (5) when sub (4) closure to be completely closed, movable cover button (5) is located at the one or both sides of lid (4), uses It is dripped in manually or automatically opening lid (4) when ECMO is run with collection membrane lung lavage.Positioned at drop accommodating cavity (5) side Scale strip (6) are set on wall, subsequent drop ingredient and the analysis of patient's pathogenicity are carried out for measuring the volume of drop.This reality It applies in example, is used as attachment device using hook (7), certainly, it is small that drop collection and transfer time due to accommodating cavity are at least 8 When, can also connect with cross bar using more firm structure, such as riveting or the mode being bonded are by the collection device and ECMO It connecting, under riveting method, a quoit is covered on cross bar, accommodating cavity is made of metal material, after the welding of metal thin bar, then with Quoit on cross bar rivets, and under bonding way, can use a variety of common adhesive of medical, and accommodating cavity can be used and be removed Other materials other than metal.Movable cover button (3) is made of metal material, and usually can be opened or is closed using manual mode, In the case where if necessary to automatic collection drop, it is connect by control device with a magnetic push rod, control device and ECMO are controlled Device real-time communication, when ECMO starting, control device issues starting control signal, and magnetic push rod pushes movable cover button (3) to open lid Sub (4), when ECMO is out of service, control device, which issues, stops control signal, and magnetic push rod pulls movable cover button (3) to close outward Closing lid (4).Lid (4) is using folding fan.Sealing strip is filled between lid (4) and drop accommodating cavity (5).Drop accommodating cavity (5) it may be set to be two (program is not shown in figure), respectively face apopore (1-1) and side opening (1-2), drop The maximum volume of accommodating cavity (5) is 20ml, and the minimum interval of droplet transfer is 8 hours.
In clinical practice, after ECMO continuous work 8 hours, it is rinsed the operation of membrane lung, collects the liquid after rinsing membrane lung Drop collects 5ml, by collection device by droplet transfer to sterile chamber, with pharynx swab pick a small amount of liquid stay specimen transfer into Row pathogenicity analysis, if can prove that ECMO operation is broken down or care environments are sent out according to there is the growth of bacterium direction Infection has been given birth to, if grown according to sterile direction, can prove ECMO operational excellence, and care environments are better.
Technical solution provided in an embodiment of the present invention is described in detail above, specific case pair used herein The principle and embodiment of the embodiment of the present invention are expounded, and the explanation of above embodiments is only applicable to help to understand this hair The principle of bright embodiment;Those of ordinary skill in the art simultaneously, according to an embodiment of the invention, in specific embodiment and There will be changes in application range, and to sum up, the contents of this specification are not to be construed as limiting the invention.

Claims (3)

1. the collection device that a kind of ECMO membrane lung rinses drop, characterized by comprising: membrane lung (1), the apopore on membrane lung (1) (1-1) and side opening (1-2), pipeline (2), drop accommodating cavity (5), the lid (4) of drop accommodating cavity (5), movable cover button (3), scale Item (6), the pipeline (2) are connect with the membrane lung (1) by cross bar, are placed the drop in the lower section of the membrane lung (1) and are held It sets chamber (5), the accommodating cavity (5) receives the drop of the apopore (1-1) and the side opening (1-2) outflow, and the drop holds It sets chamber (5) to connect by attachment device with the cross bar, sealing is filled between the lid (4) and the drop accommodating cavity (5) Item is completely closed, movable cover button (3) position so that the lid (4) is able to maintain the drop accommodating cavity (5) when being closed In the one or both sides of the lid (4), for opening the lid (4) manually or automatically when ECMO is run with collection membrane Lung lavage drop, the lid (4) are to fold fan, and the maximum volume of the drop accommodating cavity (5) is 20ml, droplet transfer Minimum interval is 8 hours, and the scale strip (6) is located in drop accommodating cavity (5) one side wall, for measuring drop Volume is made of metal material with carrying out subsequent drop ingredient and the analysis of patient's pathogenicity, the movable cover button (3), control device It is connect by a magnetic push rod with movable cover button (3), the control device and the real-time communication of ECMO controller, when the ECMO starts When, the control device issues starting control signal, and the magnetism push rod pushes the movable cover button (3) to open the lid (4), When the ECMO is out of service, the control device, which issues, stops control signal, described in the magnetism push rod pulls outward Movable cover button (3) is closed the lid (4).
2. the collection device that a kind of ECMO membrane lung according to claim 1 rinses drop, it is characterised in that: the connection dress It is set to hook, rivets or is bonded, under riveting method, a quoit is covered on the cross bar, the drop accommodating cavity is metal Material is made, and rivets after metal thin bar welding, then with the quoit on cross bar, under bonding way, using medical viscous Mixture is connect with the drop accommodating cavity of the other materials in addition to metal.
3. the collection device that a kind of ECMO membrane lung according to claim 1 rinses drop, it is characterised in that: the drop holds Setting chamber is two, respectively apopore and side opening described in face.
CN201710441581.6A 2017-06-13 2017-06-13 A kind of ECMO membrane lung flushing droplet collection device Expired - Fee Related CN107308513B (en)

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WO2024058775A1 (en) * 2022-09-14 2024-03-21 The Children's Hospital Of Philadelphia Systems and methods for oxygenating blood, passive oxygenation circuits, and neonatal extracorporeal support systems
CN117950192B (en) * 2024-03-26 2024-06-11 中山市人民医院 VR-based simulated ECMO operation method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1182072A (en) * 1968-01-08 1970-02-25 Ass Elect Ind Improvements in or relating to Vacuum Furnaces
CN102316965A (en) * 2009-05-15 2012-01-11 界面生物公司 Antithrombogenic hollow fiber membranes and filters
CN103480205A (en) * 2013-10-12 2014-01-01 攀钢集团钛业有限责任公司 Blocking-preventing drop catcher and cleaning method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001162143A (en) * 1999-12-07 2001-06-19 Nikkiso Co Ltd Medical hollow fiver membrane and method for manufacturing the same
JP5311031B2 (en) * 2009-03-02 2013-10-09 株式会社ジェイ・エム・エス Oxygenator

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1182072A (en) * 1968-01-08 1970-02-25 Ass Elect Ind Improvements in or relating to Vacuum Furnaces
CN102316965A (en) * 2009-05-15 2012-01-11 界面生物公司 Antithrombogenic hollow fiber membranes and filters
CN103480205A (en) * 2013-10-12 2014-01-01 攀钢集团钛业有限责任公司 Blocking-preventing drop catcher and cleaning method thereof

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