CN109045350A - 一种用于伤口愈合的凝胶敷料 - Google Patents

一种用于伤口愈合的凝胶敷料 Download PDF

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CN109045350A
CN109045350A CN201811165904.4A CN201811165904A CN109045350A CN 109045350 A CN109045350 A CN 109045350A CN 201811165904 A CN201811165904 A CN 201811165904A CN 109045350 A CN109045350 A CN 109045350A
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wound healing
collagen
capillarisin
lecithin
borneol
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贺文娟
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Abstract

本发明公开了一种用于伤口愈合的凝胶敷料，属于医药保健品技术领域，涉及伤口愈合。一种用于伤口愈合的凝胶敷料，包括下列重量份的各组分：齐墩果酸3‑4、芦荟微粉3‑4、胶原蛋白2‑3、卵磷脂5‑6、明胶4‑5、菊三七乙酰乙酯3、茵陈色原酮4、胶原多肽9、冰片3。本发明可以起到促进伤口快速愈合、促进肌肉组织快速生殖的作用，且能达到淡化疤痕、美容的功效。

Description

一种用于伤口愈合的凝胶敷料
技术领域
本发明属于医药保健品技术领域，涉及伤口愈合，具体涉及一种用于伤口愈合的凝胶敷料。
背景技术
皮肤伤口愈合是指由于遭受外力作用，皮肤组织出现离断或缺损后的愈复过程，包括各种组织的再生和肉芽组织增生、瘢痕组织形成的复杂组合，表现出各种过程的协同作用。最轻度的创伤仅限于皮肤表皮层；稍重者有皮肤和皮下组织断裂，并出现伤口；严重的创伤可有肌肉、肌键、神经的断裂及骨折。
伤口愈合过程为止血、炎症、增殖和重塑。为使伤口成功愈合，四个阶段须顺次完成。现有的伤口愈合药物，各成分之间很难发挥出协同增效的效果，对伤口的治疗效果不佳，存在愈合慢、愈合效果差、且容易发生反复发炎、增生的问题。
为了解决现有技术存在的上述问题，本发明研发了一种用于伤口愈合的凝胶敷料。
发明内容
本发明的目的是提供一种用于伤口愈合的凝胶敷料。
本发明是通过以下技术方案实现的：
一种用于伤口愈合的凝胶敷料，包括下列重量份的各组分：
齐墩果酸3-4 芦荟微粉3-4 胶原蛋白2-3
卵磷脂5-6 明胶4-5 菊三七乙酰乙酯3
茵陈色原酮4 胶原多肽9 冰片3。
进一步，优选包括下列重量份的各组分：
齐墩果酸4 芦荟微粉4 胶原蛋白2
卵磷脂5 明胶5 菊三七乙酰乙酯3
茵陈色原酮4 胶原多肽9 冰片3。
本发明以一定质量比的齐墩果酸、芦荟微粉、胶原蛋白为原料，以卵磷脂、明胶为载体，使用去离子水制备凝胶，作为组合物载体；通过菊三七乙酰乙酯和茵陈色原酮协同作用，对伤口进行止血、镇痛、消炎杀菌，而由于所制备的凝胶具有缓释特性，所以菊三七乙酰乙酯和载体中的齐墩果酸、芦荟微粉对伤口处起到快速止血、镇痛的作用，同时，又因为有缓释功能，所以可以防止伤口反复出血，而茵陈色原酮对伤口有很好的消炎作用，杀菌时间长，可以避免伤口的反复感染，且缓释的胶原蛋白可以进一步加强止血功效；组合物中的胶原多肽是一种细胞外蛋白质，它是纤维状蛋白质，具有促进细胞再生，淡化疤痕的作用，与缓释载体中的胶原蛋白和卵磷脂共同作用达到生肌的目的，最终冰片与各组分共同作用，促进组合物的止血、镇痛、消炎、生肌的作用。
本发明以具备缓释功效的凝胶为组合物载体，且分别与齐墩果酸、菊三七乙酰乙酯、茵陈色原酮、胶原多肽协调作用，达到快速止血，长效消炎抗菌的作用，并共同起到去腐生肌、淡化疤痕的美容效果。
本发明可以起到促进伤口快速愈合、促进肌肉组织快速生殖的作用，且能达到淡化疤痕、美容的功效。
具体实施方式
下面结合具体实施例对本发明进行进一步的说明，但应该理解，这些实施例仅用于说明本发明而不用于限制本发明的范围。本领域技术人员在本发明上对本发明作出的各种改动或修改，均应同样落于本发明的保护范围之内。
实施例1
准确称取齐墩果酸3Kg、芦荟微粉3Kg、胶原蛋白2Kg、卵磷脂6Kg、明胶5Kg、菊三七乙酰乙酯3 Kg、茵陈色原酮4 Kg、胶原多肽9 Kg、冰片3；
制备时，先将齐墩果酸、芦荟微粉、胶原蛋白、卵磷脂、明胶按照常规方法制备成缓释凝胶，然后与菊三七乙酰乙酯、茵陈色原酮、胶原多肽、冰片混合均匀，即得用于用于伤口愈合的凝胶敷料。
实施例2
准确称取齐墩果酸4Kg、芦荟微粉4Kg、胶原蛋白3Kg、卵磷脂5Kg、明胶4Kg、菊三七乙酰乙酯3 Kg、茵陈色原酮4 Kg、胶原多肽9 Kg、冰片3；
制备时，先将齐墩果酸、芦荟微粉、胶原蛋白、卵磷脂、明胶按照常规方法制备成缓释凝胶，然后与菊三七乙酰乙酯、茵陈色原酮、胶原多肽、冰片混合均匀，即得用于用于伤口愈合的凝胶敷料。
实施例3
准确称取齐墩果酸4Kg、芦荟微粉3Kg、胶原蛋白2Kg、卵磷脂5Kg、明胶4Kg、菊三七乙酰乙酯3 Kg、茵陈色原酮4 Kg、胶原多肽9 Kg、冰片3；
制备时，先将齐墩果酸、芦荟微粉、胶原蛋白、卵磷脂、明胶按照常规方法制备成缓释凝胶，然后与菊三七乙酰乙酯、茵陈色原酮、胶原多肽、冰片混合均匀，即得用于用于伤口愈合的凝胶敷料。

Claims (2)

1.一种用于伤口愈合的凝胶敷料，其特征在于，包括下列重量份的各组分：
齐墩果酸3-4 芦荟微粉3-4 胶原蛋白2-3
卵磷脂5-6 明胶4-5 菊三七乙酰乙酯3
茵陈色原酮4 胶原多肽9 冰片3。
2.一种用于伤口愈合的凝胶敷料，其特征在于，包括下列重量份的各组分：
齐墩果酸4 芦荟微粉4 胶原蛋白2
卵磷脂5 明胶5 菊三七乙酰乙酯3
茵陈色原酮4 胶原多肽9 冰片3。
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