CN109045341A - A kind of promoting blood circulation and stopping pain pressure sensitive adhesive and preparation method thereof, application - Google Patents

A kind of promoting blood circulation and stopping pain pressure sensitive adhesive and preparation method thereof, application Download PDF

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Publication number
CN109045341A
CN109045341A CN201810428138.XA CN201810428138A CN109045341A CN 109045341 A CN109045341 A CN 109045341A CN 201810428138 A CN201810428138 A CN 201810428138A CN 109045341 A CN109045341 A CN 109045341A
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parts
pressure sensitive
blood circulation
promoting blood
sensitive adhesive
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万小艾
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Wuhan Ka Yip Hing Tong Medical Technology Development Co Ltd
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Wuhan Ka Yip Hing Tong Medical Technology Development Co Ltd
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Priority to CN201810428138.XA priority Critical patent/CN109045341A/en
Publication of CN109045341A publication Critical patent/CN109045341A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/18Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/20Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28Polysaccharides or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/46Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418Agents promoting blood coagulation, blood-clotting agents, embolising agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
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  • Materials Engineering (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention provides a kind of promoting blood circulation and stopping pain pressure sensitive adhesive, is made by the raw material of following mass parts: 52.5~83.9 parts of hot melt adhesive, 16.1~47.5 parts of medicine activity component, wherein, the medicine activity component is made by the raw material of following mass parts: 1~5 part of glycerol, 1~5 part of propylene glycol, 1~5 part of atoleine, 0.5~1 part of sapn, 5~10 parts of rhizome of chuanxiong extract, 1~5 part of far-infrared powder, 1~5 part of ginger juice, 0.1~0.5 part of hydroxypropyl methyl cellulose, 0.5~1 part of azone, 5~10 parts of aromatic.The present invention also provides the preparation methods of the promoting blood circulation and stopping pain pressure sensitive adhesive, and steps are as follows: the medicine activity component being launched into hot melt adhesive, stirring, silk is not led when until being provoked with glass bar to get promoting blood circulation and stopping pain pressure sensitive adhesive is arrived.Promoting blood circulation and stopping pain pressure sensitive adhesive provided by the invention combines the antibacterial action of far-infrared powder and the promoting blood circulation and stopping pain function of rhizome of chuanxiong extract, can be effectively improved wound healing environment, while ginger juice is added and can effectively promote blood circulation, wind-expelling pain-stopping.

Description

A kind of promoting blood circulation and stopping pain pressure sensitive adhesive and preparation method thereof, application
Technical field
The present invention relates to medical dressing technical field more particularly to a kind of promoting blood circulation and stopping pain pressure sensitive adhesive and preparation method thereof, answer With.
Background technique
Pressure sensitive adhesive full name is pressure-sensitive adhesive, is a kind of adhesive for having and having sensibility to pressure, main to use In preparing pressure sensitive adhesive tape, effect is that adhesive tape is made to have the sense adhesion characteristics quick to pressure.Pressure sensitive adhesive is to be not required to heat, solvent or Other means, with finger pressure with regard to a kind of specific type adhesive of practicable bonding, under normal circumstances, pressure sensitive adhesive is not used directly In bonding, it is necessary to which being applied on banding substrate when being fabricated to various pressure sensitive adhesive products could use.
Existing medical pressure sensitive adhesive is mainly rubber, and this pressure sensitive adhesive is with natural or synthetic rubber and various additives group At antibacterial effect is poor, be easy to cause adverse reaction, although currently, the anti-inflammation and sterilization for having many scholars to be dedicated to pressure sensitive adhesive is ground Study carefully, but far-infrared powder combination rhizome of chuanxiong extract is applied in the preparation of pressure sensitive adhesive to improve antibacterial action and promoting blood circulation and stopping pain function The research of effect is less.
Summary of the invention
In view of this, additionally providing one the present invention provides a kind of promoting blood circulation and stopping pain pressure sensitive adhesive with good antibacterial action The preparation method and the application of the promoting blood circulation and stopping pain pressure sensitive adhesive on nuring wound of the promoting blood circulation and stopping pain pressure sensitive adhesive of kind simple process.
The present invention provides a kind of promoting blood circulation and stopping pain pressure sensitive adhesive, is made by the raw material of following mass parts: hot melt adhesive 52.5~83.9 Part, 16.1~47.5 parts of medicine activity component, wherein the medicine activity component is made by the raw material of following mass parts: glycerol 1 ~5 parts, 1~5 part of propylene glycol, 1~5 part of atoleine, 0.5~1 part of sapn, 5~10 parts of rhizome of chuanxiong extract, far-infrared powder 1~5 Part, 1~5 part of ginger juice, 0.1~0.5 part of hydroxypropyl methyl cellulose, 0.5~1 part of azone, 5~10 parts of aromatic.
Further, the medicine activity component is made by the raw material of following mass parts: 3.5 parts of glycerol, propylene glycol 3.5 Part, 3.5 parts of atoleine, 0.5 part of sapn, 7 parts of rhizome of chuanxiong extract, 4.5 parts of far-infrared powder, 2.8 parts of ginger juice, hydroxypropyl methyl is fine 0.25 part, 0.7 part of azone, 9 parts of aromatic of dimension element.
The present invention also provides a kind of methods for preparing the promoting blood circulation and stopping pain pressure sensitive adhesive, comprising the following steps:
S1 handles medical pressure sensitive adhesive, and hot melt adhesive is prepared;
S2 prepares medicine activity component;
The medicine activity component is launched into hot melt adhesive, is stirred at low speed by S3, is not led when until being provoked with glass bar Silk to get arrive promoting blood circulation and stopping pain pressure sensitive adhesive.
Further, the process stirred at low speed is to be stirred using agitating paddle with the speed of 30~60r/min.
Further, the hot melt adhesive is made by the following method:
S1.1 obtains the clean colloid in medical pressure sensitive adhesive, uniformly launches in melten gel tank;
S1.2 carries out low temperature melten gel to clean colloid using heater, until colloid melts, and is uniformly filled in melten gel tank It is interior;
S1.3 carries out pyrosol after the low temperature melten gel, until colloid is in liquid;
S1.4 is stirred after the pyrosol, is not led silk when until provoking colloid with glass bar, is then dropped Temperature to get arrive hot melt adhesive.
Further, in step S1.2, the temperature condition of the low temperature melten gel is 80~150 DEG C, described in step S1.3 The temperature condition of pyrosol is 151~200 DEG C.
Further, in step S1.4, the process of the stirring is with the speed of 5~20r/min using agitating paddle 151 It is stirred at~200 DEG C, colloid is cooled to 80~150 DEG C after stirring.
Further, the medicine activity component is prepared by the following method:
S2.1, weighs rhizome of chuanxiong extract and ginger juice is uniformly mixed, and heating water bath after sealing obtains mixed liquor;
Hydroxypropyl methyl cellulose is slowly added in mixed liquor made from step S2.1, stirs while adding, entirely by S2.2 After portion is added, stirring cooling obtains function phase;
S2.3 weighs glycerol, propylene glycol, atoleine, sapn, azone and far-infrared powder and is stirred, and virtue is then added Pastil stirs, and is uniformly mixed, obtains oily phase;
Function made from step S2.2 is mutually all added in oily phase, is stirred after sealing to get pharmaceutical activity group is arrived by S2.4 Point.
Further, in step S2.1, heating water bath is to 70~80 DEG C, and in step S2.2, stirring is cooled to room temperature.
Also a kind of application of the promoting blood circulation and stopping pain pressure sensitive adhesive of the present invention is applied to nuring wound, enhances bactericidal effect, promoting blood circulation Analgesic can improve wound healing environment, promote wound healing.
Technical solution provided by the invention has the benefit that promoting blood circulation and stopping pain pressure sensitive adhesive provided by the invention combines The antibacterial action of far-infrared powder and the promoting blood circulation and stopping pain function of rhizome of chuanxiong extract can be effectively improved wound healing environment, promote wound Mouth healing, while ginger juice is added and can effectively promote blood circulation, wind-expelling pain-stopping;Promoting blood circulation and stopping pain pressure sensitive adhesive provided by the invention Wound peculiar smell can be covered by the way that aromatic is added, peculiar smell is avoided to influence patient heart;Promoting blood circulation and stopping pain provided by the invention is pressure-sensitive The preparation process of glue is simple, can be realized large-scale production, has preferable industrial application value and marketing effect.
Detailed description of the invention
Fig. 1 is a kind of process schematic representation of the preparation method of promoting blood circulation and stopping pain pressure sensitive adhesive of the present invention.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, below in conjunction with attached drawing to embodiment party of the present invention Formula is further described.
With reference to Fig. 1, the embodiment provides a kind of promoting blood circulation and stopping pain pressure sensitive adhesives, by the raw material system of following mass parts : 52.5~83.9 parts of hot melt adhesive, 16.1~47.5 parts of medicine activity component, wherein the medicine activity component is by following matter The raw material for measuring part is made: 1~5 part of glycerol, 1~5 part of propylene glycol, and 1~5 part of atoleine, 0.5~1 part of sapn, rhizome of chuanxiong extract 5~10 parts, 1~5 part of far-infrared powder, 1~5 part of ginger juice, 0.1~0.5 part of hydroxypropyl methyl cellulose, 0.5~1 part of azone, virtue 5~10 parts of pastil.
Far-infrared powder is to be used as raw material using tourmaline, biological carbon etc., through special nano-powder preparation process processing At functional powder, have promote blood circulation, antibacterial, activate histocyte, prevent the function such as aging, strengthening immune system Effect.
Hot melt adhesive the preparation method comprises the following steps:
Step S1.1 obtains medical pressure sensitive adhesive, removes wrapping paper, takes out the clean colloid in it, uniformly launch into melten gel In tank;
Step S1.2 opens heater, and temperature is adjusted to 80~150 DEG C and carries out low temperature melten gel to clean colloid, until range estimation Colloid softening is melted in one piece, and is uniformly filled in melten gel tank;
The temperature of heater after low temperature melten gel, is adjusted to 151~200 DEG C of progress pyrosols by step S1.3, until Colloid is estimated in liquid;
Step S1.4, after the completion of pyrosol, starting stirring slurry is stirred evenly with the speed of 5~20r/min, keeps temperature It is stirred under conditions of 151~200 DEG C, does not lead silk, good fluidity when until provoking colloid with glass bar and close heater, dropped Temperature arrives hot melt adhesive to 80~150 DEG C.
Medicine activity component the preparation method comprises the following steps:
Step S2.1, weighs rhizome of chuanxiong extract and ginger juice is uniformly mixed, and heating water bath is mixed to 70~80 DEG C after sealing Close liquid;
Hydroxypropyl methyl cellulose is slowly added in mixed liquor made from step S2.1 by step S2.2, is stirred when being added It mixes, after being all added, stirring is cooled to room temperature, and obtains function phase;
Step S2.3 weighs glycerol, propylene glycol, atoleine, sapn, azone and far-infrared powder and is stirred, then plus Enter aromatic, stir, is uniformly mixed, obtains oily phase;
Function made from step S2.2 is mutually all added in oily phase, 10~15min is stirred after sealing, i.e., by step S2.4 Obtain medicine activity component.
The embodiments of the present invention also provide the preparation methods of above-mentioned promoting blood circulation and stopping pain pressure sensitive adhesive, comprising the following steps:
Step S1, handles medical pressure sensitive adhesive, and hot melt adhesive is prepared;
Step S2, prepares medicine activity component;
Step S3 weighs 16.1~47.5 parts of medicine activity components and launches to 52.5~83.9 parts of hot melts in parts by mass It in glue, is stirred using agitating paddle with the speed of 30~60r/min, silk is not led when until being provoked with glass bar to get work is arrived Blood and relieving pain pressure sensitive adhesive.
Specifically to promoting blood circulation and stopping pain pressure sensitive adhesive provided by the invention and preparation method thereof, using progress below with reference to embodiment It is bright.
Embodiment 1:
It weighs 7kg rhizome of chuanxiong extract and 2.8kg ginger juice pours into 50L stainless steel barrel, be uniformly mixed, covering will not after bung Rust steel drum, which is put into water bath device, is heated to 75 DEG C, obtains mixed liquor;Water bath device is big electric cooker;
Successively weigh 3.5kg glycerol, 3.5kg propylene glycol, 3.5kg atoleine, 0.5kg sapn, 0.7kg azone, 4.5kg Far-infrared powder pours into 100L plastic barrel, and slowly being stirred with clean waddy mixes it tentatively, continues after adding 9kg aromatic Stirring is sufficiently mixed uniformly, obtains oily phase;
It after prepared mixed liquor reaches 75 DEG C, is taken out from water bath device, 0.25kg hydroxypropyl methyl cellulose is delayed Slowly it pours into stainless steel barrel, the stirring of side bevelling, after being all added, stainless steel barrel cool down and stir simultaneously with cold water soak It mixes, is cooled to room temperature, obtain function phase;
Stop stirring, function is mutually all poured into the oily phase in plastic barrel, sealing continues stirring 12 minutes to get arriving 35.25kg medicine activity component;
Medical pressure sensitive adhesive is removed into wrapping paper, the clean colloid of 64.75kg is taken out, uniformly launches in melten gel tank;
Heater is opened, temperature is adjusted to 120 DEG C of progress low temperature melten gel 0.5~2 hour;
After low temperature melten gel 0.5~2 hour, temperature is adjusted to 180 DEG C of beginnings pyrosol 4~6 hours;
After the completion of pyrosol, starting stirring slurry is stirred evenly with the speed of 15r/min, and keeping temperature condition is 175 DEG C Stirring;
After the completion of stirring, the state of colloid is detected, silk, good fluidity is not led when being provoked with glass bar and closes heater, Then 110 DEG C are cooled to get to 64.75kg hot melt adhesive, 35.25kg medicine activity component is launched into 64.75kg hot melt adhesive, The mixing speed of stirring slurry is adjusted to 45r/min, is stirred evenly, until without leading silk when being provoked with glass bar, good fluidity is to get arriving Promoting blood circulation and stopping pain pressure sensitive adhesive.
In above-described embodiment 1, every 1kg is portion.
Promoting blood circulation and stopping pain pressure sensitive adhesive made from implementation 1 is coated, cuts available finished product promoting blood circulation and stopping pain pressure sensitive adhesive, is applied Cloth process are as follows: coating machine is opened in advance, is 70~120 DEG C by the temperature setting of two sebific ducts of coating machine, the temperature of dehvery pump 70~100 DEG C are set as, the temperature setting of die head is 80~130 DEG C, after the heating of equipment bulk temperature reaches requirement, preheating 10 ~40 hours, prepare coating;
The dehvery pump for being coated with total run switch and coating machine is opened, setting speed is 10~20r/min, by promoting blood circulation and stopping pain pressure Quick glue is delivered to coating head, and manually adjusting compound unwinding tension is 10~40 horsepowers, and winding tension is 20~50 horsepowers, makes medical Non-woven fabrics and release paper ensure it is smooth non-wrinkle, open coating motor, setting coating speed be 2~7r/min, adjust die head connect Distance is touched, 5-15 meters or so of examination coating is carried out;It shuts down, sampling, checks coating glue-spread, coating width;It is living to obtain finished product for cutting Blood and relieving pain pressure sensitive adhesive.
Aptitude test:
Affected part is affixed on using finished product promoting blood circulation and stopping pain pressure sensitive adhesive prepared by embodiment 1 to 30 exanthemv patients, every 2 days more It changes once, observing time is 6 days, records the healing state of patient wound, using existing medical pressure sensitive adhesive as reference, fullys recover from an illness in 30 More number 28, effective 2, the swelling time of promoting blood circulation and stopping pain pressure sensitive adhesive prepared by the present invention is shorter than existing medical pressure sensitive adhesive by 1 It, speed of wound healing is fast, does not generate scar, has no adverse reaction, and feeling of pain is substantially reduced.
Embodiment 2:
Embodiment 2 and the difference of embodiment 1 are only that: hot melt adhesive 77.3kg, glycerol 1.5kg, propylene glycol 2kg, liquid stone Wax 2.5kg, sapn 0.6kg, rhizome of chuanxiong extract 5.5kg, far-infrared powder 1.5kg, ginger juice 1.8kg, hydroxypropyl methyl cellulose 0.2kg, azone 0.6kg, aromatic 6.5kg, wherein every 1kg is portion;Remaining is then substantially the same manner as Example 1.
Embodiment 3:
Embodiment 3 and the difference of embodiment 1 are only that: hot melt adhesive 58.4kg, glycerol 4.5kg, propylene glycol 4kg, liquid stone Wax 4.5kg, sapn 0.8kg, rhizome of chuanxiong extract 8.5kg, far-infrared powder 4kg, ginger juice 4.5kg, hydroxypropyl methyl cellulose 0.4kg, azone 0.9kg, aromatic 9.5kg, wherein every 1kg is portion;Remaining is then substantially the same manner as Example 1.
Promoting blood circulation and stopping pain pressure sensitive adhesive provided by the invention combines the promoting blood circulation of the antibacterial action and rhizome of chuanxiong extract of far-infrared powder Pain-relieving functions can be effectively improved wound healing environment, promote wound healing, while ginger juice is added and can effectively promote blood Circulation, wind-expelling pain-stopping;Promoting blood circulation and stopping pain pressure sensitive adhesive provided by the invention can cover wound peculiar smell by the way that aromatic is added, and avoid different Taste influences patient heart;The preparation process of promoting blood circulation and stopping pain pressure sensitive adhesive provided by the invention is simple, can be realized large-scale production, tool There are preferable industrial application value and marketing effect.
In the absence of conflict, the feature in embodiment and embodiment herein-above set forth can be combined with each other.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all in spirit of the invention and Within principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.

Claims (10)

1. a kind of promoting blood circulation and stopping pain pressure sensitive adhesive, which is characterized in that be made by the raw material of following mass parts: hot melt adhesive 52.5~83.9 Part, 16.1~47.5 parts of medicine activity component, wherein the medicine activity component is made by the raw material of following mass parts: glycerol 1 ~5 parts, 1~5 part of propylene glycol, 1~5 part of atoleine, 0.5~1 part of sapn, 5~10 parts of rhizome of chuanxiong extract, far-infrared powder 1~5 Part, 1~5 part of ginger juice, 0.1~0.5 part of hydroxypropyl methyl cellulose, 0.5~1 part of azone, 5~10 parts of aromatic.
2. promoting blood circulation and stopping pain pressure sensitive adhesive as described in claim 1, which is characterized in that the medicine activity component is by following mass parts Raw material be made: 3.5 parts of glycerol, 3.5 parts of propylene glycol, 3.5 parts of atoleine, 0.5 part of sapn, 7 parts of rhizome of chuanxiong extract, far infrared 4.5 parts of powder, 2.8 parts of ginger juice, 0.25 part of hydroxypropyl methyl cellulose, 0.7 part of azone, 9 parts of aromatic.
3. a kind of method for preparing the described in any item promoting blood circulation and stopping pain pressure sensitive adhesives of claim 1~2, which is characterized in that including with Lower step:
S1 handles medical pressure sensitive adhesive, and hot melt adhesive is prepared;
S2 prepares medicine activity component;
The medicine activity component is launched into hot melt adhesive, is stirred at low speed by S3, does not lead silk when until being provoked with glass bar, i.e., Obtain promoting blood circulation and stopping pain pressure sensitive adhesive.
4. preparation method as claimed in claim 3, which is characterized in that the process stirred at low speed is using agitating paddle with 30 The speed of~60r/min is stirred.
5. preparation method as claimed in claim 3, which is characterized in that the hot melt adhesive is made by the following method:
S1.1 obtains the clean colloid in medical pressure sensitive adhesive, uniformly launches in melten gel tank;
S1.2 carries out low temperature melten gel to clean colloid using heater, until colloid melts, and is uniformly filled in melten gel tank;
S1.3 carries out pyrosol after the low temperature melten gel, until colloid is in liquid;
S1.4 is stirred after the pyrosol, is not led silk when until provoking colloid with glass bar, is then cooled down, i.e., Obtain hot melt adhesive.
6. preparation method as claimed in claim 5, which is characterized in that in step S1.2, the temperature condition of the low temperature melten gel It is 80~150 DEG C, in step S1.3, the temperature condition of the pyrosol is 151~200 DEG C.
7. preparation method as claimed in claim 5, which is characterized in that in step S1.4, the process of the stirring is to utilize to stir It mixes paddle to be stirred at 151~200 DEG C with the speed of 5~20r/min, colloid is cooled to 80~150 DEG C after stirring.
8. preparation method as claimed in claim 3, which is characterized in that the medicine activity component is prepared by the following method:
S2.1, weighs rhizome of chuanxiong extract and ginger juice is uniformly mixed, and heating water bath after sealing obtains mixed liquor;
Hydroxypropyl methyl cellulose is slowly added in mixed liquor made from step S2.1, stirs while adding by S2.2, all adds After entering, stirring cooling obtains function phase;
S2.3 weighs glycerol, propylene glycol, atoleine, sapn, azone and far-infrared powder and is stirred, aromatic is then added, Stirring is uniformly mixed, obtains oily phase;
Function made from step S2.2 is mutually all added in oily phase, is stirred after sealing to get medicine activity component is arrived by S2.4.
9. preparation method as claimed in claim 8, which is characterized in that in step S2.1, heating water bath is to 70~80 DEG C, step In S2.2, stirring is cooled to room temperature.
10. a kind of application of the described in any item promoting blood circulation and stopping pain pressure sensitive adhesives of claim 1~2, which is characterized in that be applied to nursing Wound enhances bactericidal effect, and promoting blood circulation and stopping pain can improve wound healing environment, promotes wound healing.
CN201810428138.XA 2018-05-07 2018-05-07 A kind of promoting blood circulation and stopping pain pressure sensitive adhesive and preparation method thereof, application Pending CN109045341A (en)

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