CN109045095A - A kind of preparation method of production of sperm antifatigue food formula and the pharmaceutical formulation - Google Patents

A kind of preparation method of production of sperm antifatigue food formula and the pharmaceutical formulation Download PDF

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CN109045095A
CN109045095A CN201810972944.3A CN201810972944A CN109045095A CN 109045095 A CN109045095 A CN 109045095A CN 201810972944 A CN201810972944 A CN 201810972944A CN 109045095 A CN109045095 A CN 109045095A
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powder
parts
sperm
maca
concentrated
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马玉娟
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
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  • Botany (AREA)
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  • Alternative & Traditional Medicine (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Toxicology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses the preparation methods of a kind of production of sperm antifatigue food formula and the pharmaceutical formulation, production of sperm antifatigue food formula is made of the raw material of following parts by weight: male silk moth is concentrated powder 1-10 parts, and Maca is concentrated powder 1-15 parts, 1-5 parts of truffle, 1-10 parts of Herba Epimedii, tablet is made according to certain technique in the formula, conveniently takes, and the formula and its preparation have good Spermatogenic action, improve sperm quantity and vigor, it relieves fatigue, strengthen immunity, effect is lasting.

Description

A kind of preparation method of production of sperm antifatigue food formula and the pharmaceutical formulation
Technical field
The invention belongs to technical field of food preparation more particularly to a kind of production of sperm antifatigue food formulas and the pharmaceutical formulation Preparation method.
Background technique
Modern society's life rhythm is fast, and dog-eat-dog, pressure is big, in addition various undesirable living habits, human-body sub-health State is on the rise, and soreness and weakness of waist and knees occurs, impotence is not lifted, kidney deficiency essence is sliding, or even few essence, the crowd of weak smart, dead essence are gradually young Change, sub-health state shows as the symptom of the vigor decline of certain time, function and adaptability decline, and man is mainly reflected in Sperm quantity is few, vigor is poor or even sex dysfunction etc..Love life is caused to be discord even infertile.
In recent years, both at home and abroad for how improving man's production of sperm ability and quality of life expands a large amount of medical research, Western medicine is while curative effect occurs, also with various side effects, therefore it provides a kind of have obvious production of sperm and antifatigue and secondary work With small formula, while the preparation conveniently taken can be made, have important practical significance.
Summary of the invention
The present invention provides a kind of production of sperm antifatigue food formula and the preparation method of the pharmaceutical formulation, medicine food formula and its Preparation has good Spermatogenic action, improves sperm quantity and vigor, relieves fatigue, effect is lasting, and side effect is minimum.
The technical scheme adopted by the invention is as follows:
A kind of production of sperm antifatigue food formula, be made of the raw material of following parts by weight: male silk moth is concentrated powder 1-10 parts, and Maca is dense 1-15 parts of contracting powder, 1-5 parts of truffle, 1-10 parts of Herba Epimedii.
Preferably, be made of the raw material of following parts by weight: male silk moth is concentrated 5 parts of powder, and Maca is concentrated 7 parts of powder, truffle 3 Part, 5 parts of Herba Epimedii.
The present invention also provides the preparation methods of above-mentioned production of sperm antifatigue food pharmaceutical formulation, follow the steps below:
(1) male silk moth concentration powder preparation: male silk moth medicinal extract 100g is taken, 100ml-2000ml dehydrated alcohol is added, stirs 1min- 60min is filtered, and filter residue is taken to beat powder after 15 DEG C of -60 DEG C of drying;
(2) Maca concentration powder preparation
A, Maca 400g is taken, 4000ml50%-70% ethyl alcohol is added after crushing and is stirred overnight, ultrasonic extraction 1min-60min, filtering, It takes filtrate decompression to be concentrated into 100ml and obtains Maca medicinal extract;
B, above-mentioned medicinal extract is taken, dehydrated alcohol 1000ml is added, 1min-60min is stirred, is put into -20 DEG C of refrigerator overnights, is filtered;
C, it takes 40 DEG C of above-mentioned filtrate to be concentrated under reduced pressure into 100ml, dehydrated alcohol 1000ml is added, stir 1min-60min, stand and divide It is filtered after layer;
D, it takes filtrate that 1.0g -8.0g superfine silica gel powder is added, stirs 1min-60min, be concentrated under reduced pressure, obtain faint yellow solid, beat powder To obtain the final product;
(3) truffle, raspberry, Herba Epimedii are beaten into powder;
(4) powder of above-mentioned preparation is mixed, tabletting.
In the present invention, in formula the effect of ingredients are as follows:
Male silk moth: active material rich in, male sex hormone rich content, to enhancing human immunity and sexual function effect is aobvious It writes.
Maca: for enhancing energy, improving fertility, treatment climacteric syndrome, rheumatism, depression, anemia, also Have the effects that anticancer and anti-leukocythemia.
Truffle: protein rich in, 18 kinds of amino acid (the 8 kinds of essential amino acids that cannot be synthesized including human body), no The essential trace elements such as saturated fatty acid, multivitamin, zinc, manganese, iron, calcium, phosphorus, selenium and sphingolipid, cerebroside, nerve The a large amount of metabolites such as amide, triterpene, androsterone, adenosine, truffle acid, sterol, truffle polysaccharide, truffle polypeptide have high Healthy nutritive value.Wherein androsterone has supporing yang, the endocrine remarkable efficacy of conditioning;Sphingolipid compound is preventing old be crazy about There is obvious activity in terms of slow-witted, atherosclerosis and antitumor cell toxicity;Polysaccharide, polypeptide, triterpene have strengthen immunity, Anti-aging, fatigue-resisting function.
Raspberry: it is sweet in flavor, sour, it is warm-natured, there is supplementing the kidney to control the nocturnal reducing urination, the effect of nourishing the liver to improve visual acuity, be used for emission and spermatorrhea, the enuresis Frequent micturition, impotence and premature ejaculation, mesh are secretly dim-sighted.
Herba Epimedii: it is pungent, sweet, warm, have effects that tonifying kidney and strengthening yang, dispelling wind and eliminating dampness, strong muscles and bones.
Formula of the invention is simple, and definite effect, preparation process is simple to operation, convenient for promoting, the formula and its preparation With good Spermatogenic action, sperm quantity and vigor are improved, is relieved fatigue, effect is lasting, and pharmaceutically acceptable also edible, secondary It acts on minimum.
Specific embodiment
Embodiment 1
A kind of production of sperm antifatigue food formula, is made of the raw material of following parts by weight: male silk moth is concentrated 1 part of powder, Maca concentration 7 parts of powder, 2 parts of truffle, 10 parts of Herba Epimedii.
The pharmaceutical formulation is prepared in accordance with the following methods:
(1) male silk moth concentration powder preparation: male silk moth medicinal extract 100g is taken, 100ml dehydrated alcohol is added, stirs 60min, filters, takes Filter residue beats powder after 15 DEG C of drying;
(2) Maca concentration powder preparation
A, Maca 400g is taken, 4000ml50% ethyl alcohol is added after crushing and is stirred overnight, ultrasonic extraction 60min, filtering takes filtrate to subtract Pressure is concentrated into 100ml and obtains Maca medicinal extract;
B, above-mentioned medicinal extract is taken, dehydrated alcohol 1000ml is added, 1h is stirred, is put into -20 DEG C of refrigerator overnights, is filtered;
C, it takes 40 DEG C of above-mentioned filtrate to be concentrated under reduced pressure into 100ml, dehydrated alcohol 1000ml is added, stir 1h, filtered after stratification;
D, it takes filtrate that 1.0g superfine silica gel powder is added, stirs 1min, be concentrated under reduced pressure, obtain faint yellow solid, beat powder to obtain the final product;
(3) truffle, raspberry, Herba Epimedii are beaten into powder;
(4) powder of above-mentioned preparation is mixed, tabletting.
Embodiment 2
A kind of production of sperm antifatigue food formula, is made of the raw material of following parts by weight: male silk moth is concentrated 5 parts of powder, Maca concentration 1 part of powder, 1 part of truffle, 5 parts of Herba Epimedii.
The pharmaceutical formulation is prepared in accordance with the following methods:
(1) male silk moth concentration powder preparation: male silk moth medicinal extract 100g is taken, 1200ml dehydrated alcohol is added, stirs 30min, filters, takes Filter residue beats powder after 40 DEG C of drying;
(2) Maca concentration powder preparation
A, Maca 400g is taken, 4000ml60% ethyl alcohol is added after crushing and is stirred overnight, ultrasonic extraction 30min, filtering takes filtrate to subtract Pressure is concentrated into 100ml and obtains Maca medicinal extract;
B, above-mentioned medicinal extract is taken, dehydrated alcohol 1000ml is added, 1h is stirred, is put into -20 DEG C of refrigerator overnights, is filtered;
C, it takes 40 DEG C of above-mentioned filtrate to be concentrated under reduced pressure into 100ml, dehydrated alcohol 1000ml is added, stir 1h, filtered after stratification;
D, it takes filtrate that 5.0g superfine silica gel powder is added, stirs 30min, be concentrated under reduced pressure, obtain faint yellow solid, beat powder to obtain the final product;
(3) truffle, raspberry, Herba Epimedii are beaten into powder;
(4) powder of above-mentioned preparation is mixed, tabletting.
Embodiment 3
A kind of production of sperm antifatigue food formula, is made of the raw material of following parts by weight: male silk moth is concentrated 10 parts of powder, Maca concentration 15 parts of powder, 5 parts of truffle, 1 part of Herba Epimedii.
The pharmaceutical formulation is prepared in accordance with the following methods:
(1) male silk moth concentration powder preparation: male silk moth medicinal extract 100g is taken, 2000ml dehydrated alcohol is added, stirs 1min, filters, takes Filter residue beats powder after 60 DEG C of drying;
(2) Maca concentration powder preparation
A, Maca 400g is taken, 4000ml70% ethyl alcohol is added after crushing and is stirred overnight, ultrasonic extraction 1min, filtering takes filtrate decompression It is concentrated into 100ml and obtains Maca medicinal extract;
B, above-mentioned medicinal extract is taken, dehydrated alcohol 1000ml is added, 1h is stirred, is put into -20 DEG C of refrigerator overnights, is filtered;
C, it takes 40 DEG C of above-mentioned filtrate to be concentrated under reduced pressure into 100ml, dehydrated alcohol 1000ml is added, stir 1h, filtered after stratification;
D, it takes filtrate that 8.0g superfine silica gel powder is added, stirs 60min, be concentrated under reduced pressure, obtain faint yellow solid, beat powder to obtain the final product;
(3) truffle, raspberry, Herba Epimedii are beaten into powder.

Claims (4)

1. a kind of production of sperm antifatigue food formula, which is characterized in that be made of following raw material: powder, Maca concentration is concentrated in male silk moth Powder, truffle, Herba Epimedii.
2. a kind of production of sperm antifatigue food formula, which is characterized in that be made of the raw material of following parts by weight: powder is concentrated in male silk moth 1-10 parts, Maca is concentrated powder 1-15 parts, 1-5 parts of truffle, 1-10 parts of Herba Epimedii.
3. a kind of production of sperm antifatigue food formula according to claim 1, which is characterized in that by the original of following parts by weight Material composition: male silk moth is concentrated 5 parts of powder, and Maca is concentrated 7 parts of powder, 3 parts of truffle, 5 parts of Herba Epimedii.
4. a kind of preparation method of production of sperm antifatigue food pharmaceutical formulation according to claim 1 or 2, which is characterized in that It follows the steps below:
(1) male silk moth concentration powder preparation: male silk moth medicinal extract 100g is taken, 100ml-2000ml dehydrated alcohol is added, stirs 1min- 60min is filtered, and filter residue is taken to beat powder after 15 DEG C of -60 DEG C of drying;
(2) Maca concentration powder preparation
A, Maca 400g is taken, 100ml-4000ml is added after crushing, 50%-70% ethyl alcohol stirs, ultrasonic extraction 1min-60min, Filtering, takes filtrate decompression to be concentrated into 100ml and obtains Maca medicinal extract;
B, above-mentioned medicinal extract is taken, dehydrated alcohol 1000ml is added, 1min-60min is stirred, is put into -20 DEG C of refrigerator overnights, is filtered;
C, it takes 40 DEG C of above-mentioned filtrate to be concentrated under reduced pressure into 100ml, dehydrated alcohol 1000ml is added, stir 1min-60min, stand and divide It is filtered after layer;
D, it takes filtrate that 1.0g -8.0g superfine silica gel powder is added, stirs 1min-60min, be concentrated under reduced pressure, obtain faint yellow solid, beat powder To obtain the final product;
(3) truffle, Herba Epimedii are beaten into powder;
(4) powder of above-mentioned preparation is mixed, tabletting.
CN201810972944.3A 2018-08-24 2018-08-24 A kind of preparation method of production of sperm antifatigue food formula and the pharmaceutical formulation Pending CN109045095A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101313749A (en) * 2008-07-08 2008-12-03 北方绿色食品股份有限公司 Male silk moth capsule and its preparing process
UA87678C2 (en) * 2006-09-18 2009-08-10 Общество С Ограниченной Ответственностью Научно-Производственная Фармацевтическая Компания "Эйм" Phytotherapeutic composition for treating diseases of prostate
CN106509900A (en) * 2016-11-16 2017-03-22 马玉娟 Tuber magnatum health-care product

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA87678C2 (en) * 2006-09-18 2009-08-10 Общество С Ограниченной Ответственностью Научно-Производственная Фармацевтическая Компания "Эйм" Phytotherapeutic composition for treating diseases of prostate
CN101313749A (en) * 2008-07-08 2008-12-03 北方绿色食品股份有限公司 Male silk moth capsule and its preparing process
CN106509900A (en) * 2016-11-16 2017-03-22 马玉娟 Tuber magnatum health-care product

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
钟赣生: "《中药学》", 31 May 2012, 中国中医药出版社 *
陈新谦等: "《新编药物学》", 31 December 1998, 人民卫生出版社 *

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Application publication date: 20181221