CN109045095A - A kind of preparation method of production of sperm antifatigue food formula and the pharmaceutical formulation - Google Patents
A kind of preparation method of production of sperm antifatigue food formula and the pharmaceutical formulation Download PDFInfo
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- CN109045095A CN109045095A CN201810972944.3A CN201810972944A CN109045095A CN 109045095 A CN109045095 A CN 109045095A CN 201810972944 A CN201810972944 A CN 201810972944A CN 109045095 A CN109045095 A CN 109045095A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 27
- 235000013305 food Nutrition 0.000 title claims abstract description 17
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 17
- 230000002929 anti-fatigue Effects 0.000 title claims abstract description 16
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 10
- 239000000843 powder Substances 0.000 claims abstract description 52
- 235000000421 Lepidium meyenii Nutrition 0.000 claims abstract description 25
- 240000000759 Lepidium meyenii Species 0.000 claims abstract description 25
- 235000012902 lepidium meyenii Nutrition 0.000 claims abstract description 25
- 241000255789 Bombyx mori Species 0.000 claims abstract description 20
- 241000609666 Tuber aestivum Species 0.000 claims abstract description 18
- 239000002994 raw material Substances 0.000 claims abstract description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 25
- 238000003756 stirring Methods 0.000 claims description 16
- 229960000935 dehydrated alcohol Drugs 0.000 claims description 15
- 239000000706 filtrate Substances 0.000 claims description 15
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 5
- 229960004756 ethanol Drugs 0.000 claims description 5
- 235000019441 ethanol Nutrition 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 239000012467 final product Substances 0.000 claims description 5
- 239000000741 silica gel Substances 0.000 claims description 5
- 229910002027 silica gel Inorganic materials 0.000 claims description 5
- 239000007787 solid Substances 0.000 claims description 5
- 238000002137 ultrasound extraction Methods 0.000 claims description 5
- 230000006837 decompression Effects 0.000 claims description 3
- 239000000463 material Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 13
- 238000000034 method Methods 0.000 abstract description 5
- 230000036039 immunity Effects 0.000 abstract description 3
- 230000002045 lasting effect Effects 0.000 abstract description 3
- 230000000920 spermatogeneic effect Effects 0.000 abstract description 3
- 235000011034 Rubus glaucus Nutrition 0.000 description 5
- 235000009122 Rubus idaeus Nutrition 0.000 description 5
- 240000007651 Rubus glaucus Species 0.000 description 4
- 210000003734 kidney Anatomy 0.000 description 3
- 238000013517 stratification Methods 0.000 description 3
- QGXBDMJGAMFCBF-HLUDHZFRSA-N 5α-Androsterone Chemical compound C1[C@H](O)CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC[C@H]21 QGXBDMJGAMFCBF-HLUDHZFRSA-N 0.000 description 2
- QGXBDMJGAMFCBF-UHFFFAOYSA-N Etiocholanolone Natural products C1C(O)CCC2(C)C3CCC(C)(C(CC4)=O)C4C3CCC21 QGXBDMJGAMFCBF-UHFFFAOYSA-N 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 2
- 229940061641 androsterone Drugs 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 201000001881 impotence Diseases 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- -1 multivitamin Substances 0.000 description 2
- 229920001184 polypeptide Polymers 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 150000003648 triterpenes Chemical class 0.000 description 2
- JSPNNZKWADNWHI-PNANGNLXSA-N (2r)-2-hydroxy-n-[(2s,3r,4e,8e)-3-hydroxy-9-methyl-1-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadeca-4,8-dien-2-yl]heptadecanamide Chemical compound CCCCCCCCCCCCCCC[C@@H](O)C(=O)N[C@H]([C@H](O)\C=C\CC\C=C(/C)CCCCCCCCC)CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O JSPNNZKWADNWHI-PNANGNLXSA-N 0.000 description 1
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 239000002126 C01EB10 - Adenosine Substances 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 208000008967 Enuresis Diseases 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 244000235659 Rubus idaeus Species 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- 206010041497 Spermatorrhoea Diseases 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 229960005305 adenosine Drugs 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 230000007541 cellular toxicity Effects 0.000 description 1
- 229930183167 cerebroside Natural products 0.000 description 1
- RIZIAUKTHDLMQX-UHFFFAOYSA-N cerebroside D Natural products CCCCCCCCCCCCCCCCC(O)C(=O)NC(C(O)C=CCCC=C(C)CCCCCCCCC)COC1OC(CO)C(O)C(O)C1O RIZIAUKTHDLMQX-UHFFFAOYSA-N 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 239000003797 essential amino acid Substances 0.000 description 1
- 235000020776 essential amino acid Nutrition 0.000 description 1
- 230000035558 fertility Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000003163 gonadal steroid hormone Substances 0.000 description 1
- 208000021267 infertility disease Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000000422 nocturnal effect Effects 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 206010036596 premature ejaculation Diseases 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 230000036299 sexual function Effects 0.000 description 1
- 150000003408 sphingolipids Chemical class 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 230000004304 visual acuity Effects 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Insects & Arthropods (AREA)
- Toxicology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Nutrition Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses the preparation methods of a kind of production of sperm antifatigue food formula and the pharmaceutical formulation, production of sperm antifatigue food formula is made of the raw material of following parts by weight: male silk moth is concentrated powder 1-10 parts, and Maca is concentrated powder 1-15 parts, 1-5 parts of truffle, 1-10 parts of Herba Epimedii, tablet is made according to certain technique in the formula, conveniently takes, and the formula and its preparation have good Spermatogenic action, improve sperm quantity and vigor, it relieves fatigue, strengthen immunity, effect is lasting.
Description
Technical field
The invention belongs to technical field of food preparation more particularly to a kind of production of sperm antifatigue food formulas and the pharmaceutical formulation
Preparation method.
Background technique
Modern society's life rhythm is fast, and dog-eat-dog, pressure is big, in addition various undesirable living habits, human-body sub-health
State is on the rise, and soreness and weakness of waist and knees occurs, impotence is not lifted, kidney deficiency essence is sliding, or even few essence, the crowd of weak smart, dead essence are gradually young
Change, sub-health state shows as the symptom of the vigor decline of certain time, function and adaptability decline, and man is mainly reflected in
Sperm quantity is few, vigor is poor or even sex dysfunction etc..Love life is caused to be discord even infertile.
In recent years, both at home and abroad for how improving man's production of sperm ability and quality of life expands a large amount of medical research,
Western medicine is while curative effect occurs, also with various side effects, therefore it provides a kind of have obvious production of sperm and antifatigue and secondary work
With small formula, while the preparation conveniently taken can be made, have important practical significance.
Summary of the invention
The present invention provides a kind of production of sperm antifatigue food formula and the preparation method of the pharmaceutical formulation, medicine food formula and its
Preparation has good Spermatogenic action, improves sperm quantity and vigor, relieves fatigue, effect is lasting, and side effect is minimum.
The technical scheme adopted by the invention is as follows:
A kind of production of sperm antifatigue food formula, be made of the raw material of following parts by weight: male silk moth is concentrated powder 1-10 parts, and Maca is dense
1-15 parts of contracting powder, 1-5 parts of truffle, 1-10 parts of Herba Epimedii.
Preferably, be made of the raw material of following parts by weight: male silk moth is concentrated 5 parts of powder, and Maca is concentrated 7 parts of powder, truffle 3
Part, 5 parts of Herba Epimedii.
The present invention also provides the preparation methods of above-mentioned production of sperm antifatigue food pharmaceutical formulation, follow the steps below:
(1) male silk moth concentration powder preparation: male silk moth medicinal extract 100g is taken, 100ml-2000ml dehydrated alcohol is added, stirs 1min-
60min is filtered, and filter residue is taken to beat powder after 15 DEG C of -60 DEG C of drying;
(2) Maca concentration powder preparation
A, Maca 400g is taken, 4000ml50%-70% ethyl alcohol is added after crushing and is stirred overnight, ultrasonic extraction 1min-60min, filtering,
It takes filtrate decompression to be concentrated into 100ml and obtains Maca medicinal extract;
B, above-mentioned medicinal extract is taken, dehydrated alcohol 1000ml is added, 1min-60min is stirred, is put into -20 DEG C of refrigerator overnights, is filtered;
C, it takes 40 DEG C of above-mentioned filtrate to be concentrated under reduced pressure into 100ml, dehydrated alcohol 1000ml is added, stir 1min-60min, stand and divide
It is filtered after layer;
D, it takes filtrate that 1.0g -8.0g superfine silica gel powder is added, stirs 1min-60min, be concentrated under reduced pressure, obtain faint yellow solid, beat powder
To obtain the final product;
(3) truffle, raspberry, Herba Epimedii are beaten into powder;
(4) powder of above-mentioned preparation is mixed, tabletting.
In the present invention, in formula the effect of ingredients are as follows:
Male silk moth: active material rich in, male sex hormone rich content, to enhancing human immunity and sexual function effect is aobvious
It writes.
Maca: for enhancing energy, improving fertility, treatment climacteric syndrome, rheumatism, depression, anemia, also
Have the effects that anticancer and anti-leukocythemia.
Truffle: protein rich in, 18 kinds of amino acid (the 8 kinds of essential amino acids that cannot be synthesized including human body), no
The essential trace elements such as saturated fatty acid, multivitamin, zinc, manganese, iron, calcium, phosphorus, selenium and sphingolipid, cerebroside, nerve
The a large amount of metabolites such as amide, triterpene, androsterone, adenosine, truffle acid, sterol, truffle polysaccharide, truffle polypeptide have high
Healthy nutritive value.Wherein androsterone has supporing yang, the endocrine remarkable efficacy of conditioning;Sphingolipid compound is preventing old be crazy about
There is obvious activity in terms of slow-witted, atherosclerosis and antitumor cell toxicity;Polysaccharide, polypeptide, triterpene have strengthen immunity,
Anti-aging, fatigue-resisting function.
Raspberry: it is sweet in flavor, sour, it is warm-natured, there is supplementing the kidney to control the nocturnal reducing urination, the effect of nourishing the liver to improve visual acuity, be used for emission and spermatorrhea, the enuresis
Frequent micturition, impotence and premature ejaculation, mesh are secretly dim-sighted.
Herba Epimedii: it is pungent, sweet, warm, have effects that tonifying kidney and strengthening yang, dispelling wind and eliminating dampness, strong muscles and bones.
Formula of the invention is simple, and definite effect, preparation process is simple to operation, convenient for promoting, the formula and its preparation
With good Spermatogenic action, sperm quantity and vigor are improved, is relieved fatigue, effect is lasting, and pharmaceutically acceptable also edible, secondary
It acts on minimum.
Specific embodiment
Embodiment 1
A kind of production of sperm antifatigue food formula, is made of the raw material of following parts by weight: male silk moth is concentrated 1 part of powder, Maca concentration
7 parts of powder, 2 parts of truffle, 10 parts of Herba Epimedii.
The pharmaceutical formulation is prepared in accordance with the following methods:
(1) male silk moth concentration powder preparation: male silk moth medicinal extract 100g is taken, 100ml dehydrated alcohol is added, stirs 60min, filters, takes
Filter residue beats powder after 15 DEG C of drying;
(2) Maca concentration powder preparation
A, Maca 400g is taken, 4000ml50% ethyl alcohol is added after crushing and is stirred overnight, ultrasonic extraction 60min, filtering takes filtrate to subtract
Pressure is concentrated into 100ml and obtains Maca medicinal extract;
B, above-mentioned medicinal extract is taken, dehydrated alcohol 1000ml is added, 1h is stirred, is put into -20 DEG C of refrigerator overnights, is filtered;
C, it takes 40 DEG C of above-mentioned filtrate to be concentrated under reduced pressure into 100ml, dehydrated alcohol 1000ml is added, stir 1h, filtered after stratification;
D, it takes filtrate that 1.0g superfine silica gel powder is added, stirs 1min, be concentrated under reduced pressure, obtain faint yellow solid, beat powder to obtain the final product;
(3) truffle, raspberry, Herba Epimedii are beaten into powder;
(4) powder of above-mentioned preparation is mixed, tabletting.
Embodiment 2
A kind of production of sperm antifatigue food formula, is made of the raw material of following parts by weight: male silk moth is concentrated 5 parts of powder, Maca concentration
1 part of powder, 1 part of truffle, 5 parts of Herba Epimedii.
The pharmaceutical formulation is prepared in accordance with the following methods:
(1) male silk moth concentration powder preparation: male silk moth medicinal extract 100g is taken, 1200ml dehydrated alcohol is added, stirs 30min, filters, takes
Filter residue beats powder after 40 DEG C of drying;
(2) Maca concentration powder preparation
A, Maca 400g is taken, 4000ml60% ethyl alcohol is added after crushing and is stirred overnight, ultrasonic extraction 30min, filtering takes filtrate to subtract
Pressure is concentrated into 100ml and obtains Maca medicinal extract;
B, above-mentioned medicinal extract is taken, dehydrated alcohol 1000ml is added, 1h is stirred, is put into -20 DEG C of refrigerator overnights, is filtered;
C, it takes 40 DEG C of above-mentioned filtrate to be concentrated under reduced pressure into 100ml, dehydrated alcohol 1000ml is added, stir 1h, filtered after stratification;
D, it takes filtrate that 5.0g superfine silica gel powder is added, stirs 30min, be concentrated under reduced pressure, obtain faint yellow solid, beat powder to obtain the final product;
(3) truffle, raspberry, Herba Epimedii are beaten into powder;
(4) powder of above-mentioned preparation is mixed, tabletting.
Embodiment 3
A kind of production of sperm antifatigue food formula, is made of the raw material of following parts by weight: male silk moth is concentrated 10 parts of powder, Maca concentration
15 parts of powder, 5 parts of truffle, 1 part of Herba Epimedii.
The pharmaceutical formulation is prepared in accordance with the following methods:
(1) male silk moth concentration powder preparation: male silk moth medicinal extract 100g is taken, 2000ml dehydrated alcohol is added, stirs 1min, filters, takes
Filter residue beats powder after 60 DEG C of drying;
(2) Maca concentration powder preparation
A, Maca 400g is taken, 4000ml70% ethyl alcohol is added after crushing and is stirred overnight, ultrasonic extraction 1min, filtering takes filtrate decompression
It is concentrated into 100ml and obtains Maca medicinal extract;
B, above-mentioned medicinal extract is taken, dehydrated alcohol 1000ml is added, 1h is stirred, is put into -20 DEG C of refrigerator overnights, is filtered;
C, it takes 40 DEG C of above-mentioned filtrate to be concentrated under reduced pressure into 100ml, dehydrated alcohol 1000ml is added, stir 1h, filtered after stratification;
D, it takes filtrate that 8.0g superfine silica gel powder is added, stirs 60min, be concentrated under reduced pressure, obtain faint yellow solid, beat powder to obtain the final product;
(3) truffle, raspberry, Herba Epimedii are beaten into powder.
Claims (4)
1. a kind of production of sperm antifatigue food formula, which is characterized in that be made of following raw material: powder, Maca concentration is concentrated in male silk moth
Powder, truffle, Herba Epimedii.
2. a kind of production of sperm antifatigue food formula, which is characterized in that be made of the raw material of following parts by weight: powder is concentrated in male silk moth
1-10 parts, Maca is concentrated powder 1-15 parts, 1-5 parts of truffle, 1-10 parts of Herba Epimedii.
3. a kind of production of sperm antifatigue food formula according to claim 1, which is characterized in that by the original of following parts by weight
Material composition: male silk moth is concentrated 5 parts of powder, and Maca is concentrated 7 parts of powder, 3 parts of truffle, 5 parts of Herba Epimedii.
4. a kind of preparation method of production of sperm antifatigue food pharmaceutical formulation according to claim 1 or 2, which is characterized in that
It follows the steps below:
(1) male silk moth concentration powder preparation: male silk moth medicinal extract 100g is taken, 100ml-2000ml dehydrated alcohol is added, stirs 1min-
60min is filtered, and filter residue is taken to beat powder after 15 DEG C of -60 DEG C of drying;
(2) Maca concentration powder preparation
A, Maca 400g is taken, 100ml-4000ml is added after crushing, 50%-70% ethyl alcohol stirs, ultrasonic extraction 1min-60min,
Filtering, takes filtrate decompression to be concentrated into 100ml and obtains Maca medicinal extract;
B, above-mentioned medicinal extract is taken, dehydrated alcohol 1000ml is added, 1min-60min is stirred, is put into -20 DEG C of refrigerator overnights, is filtered;
C, it takes 40 DEG C of above-mentioned filtrate to be concentrated under reduced pressure into 100ml, dehydrated alcohol 1000ml is added, stir 1min-60min, stand and divide
It is filtered after layer;
D, it takes filtrate that 1.0g -8.0g superfine silica gel powder is added, stirs 1min-60min, be concentrated under reduced pressure, obtain faint yellow solid, beat powder
To obtain the final product;
(3) truffle, Herba Epimedii are beaten into powder;
(4) powder of above-mentioned preparation is mixed, tabletting.
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101313749A (en) * | 2008-07-08 | 2008-12-03 | 北方绿色食品股份有限公司 | Male silk moth capsule and its preparing process |
UA87678C2 (en) * | 2006-09-18 | 2009-08-10 | Общество С Ограниченной Ответственностью Научно-Производственная Фармацевтическая Компания "Эйм" | Phytotherapeutic composition for treating diseases of prostate |
CN106509900A (en) * | 2016-11-16 | 2017-03-22 | 马玉娟 | Tuber magnatum health-care product |
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2018
- 2018-08-24 CN CN201810972944.3A patent/CN109045095A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA87678C2 (en) * | 2006-09-18 | 2009-08-10 | Общество С Ограниченной Ответственностью Научно-Производственная Фармацевтическая Компания "Эйм" | Phytotherapeutic composition for treating diseases of prostate |
CN101313749A (en) * | 2008-07-08 | 2008-12-03 | 北方绿色食品股份有限公司 | Male silk moth capsule and its preparing process |
CN106509900A (en) * | 2016-11-16 | 2017-03-22 | 马玉娟 | Tuber magnatum health-care product |
Non-Patent Citations (2)
Title |
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钟赣生: "《中药学》", 31 May 2012, 中国中医药出版社 * |
陈新谦等: "《新编药物学》", 31 December 1998, 人民卫生出版社 * |
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