CN109044599A - A kind of anti-inflammatory sheath and its production method - Google Patents

A kind of anti-inflammatory sheath and its production method Download PDF

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Publication number
CN109044599A
CN109044599A CN201810726745.4A CN201810726745A CN109044599A CN 109044599 A CN109044599 A CN 109044599A CN 201810726745 A CN201810726745 A CN 201810726745A CN 109044599 A CN109044599 A CN 109044599A
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China
Prior art keywords
parts
sheath
elastic ring
medicine composition
inflammatory
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Granted
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CN201810726745.4A
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CN109044599B (en
Inventor
屈正炎
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Beijing Elephant And His Friends Technology Co ltd
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Bengbu Ke Ruida Machinery Design Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/02Contraceptive devices; Pessaries; Applicators therefor for use by males
    • A61F6/04Condoms, sheaths or the like, e.g. combined with devices protecting against contagion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234Cnidium (snowparsley)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/38Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Alternative & Traditional Medicine (AREA)
  • Reproductive Health (AREA)
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Abstract

The invention discloses a kind of anti-inflammatory sheath and its production methods.The anti-inflammatory sheath includes body and the elastic ring set on body open end, spray attachment sheath matrix and Chinese traditional medicine composition on the body, the elastic ring is joined end to end by a linear main body, the cross section of the threadiness main body is circle, the threadiness main body head end is coaxially arranged with outer pillar, massiveness has several elastic chip cards on the outer pillar, the threadiness body trailing end is formed with the circular groove with the inserting cooperation of outer pillar, several annular grooves are uniformly opened up on the circular groove inner wall, the quantity of the annular groove and chip card, it is spaced identical and is able to achieve clamping engagement.Anti-inflammatory sheath of the invention overcomes technology prejudice, and the elastic of elastic ring can be adjusted as needed, and elastic ring is mobilizable in vivo to facilitate adjusting in set, and outer pillar and circular groove plug conveniently, and annular groove is easy easy to adjust in conjunction with chip card.

Description

A kind of anti-inflammatory sheath and its production method
Technical field
The present invention relates to amenities, more particularly, to a kind of anti-inflammatory sheath and its production method.
Background technique
Sheath is to prevent to become pregnant in the form of non-drug, is mainly used for preventing the sperm and ovum knot of the mankind in sexual intercourse It closes, prevents from being pregnant.In addition to this, sheath also prevents the spread of sexually transmitted diseases such as stranguria syndrome, AIDS (HIV), therefore also referred to as Condom, present sheath raw material are usually to use natural rubber or polyurethane.
All effects of existing sheath are limited only to passively to prevent that active treatment can not be played based on disease The effect of disease.
In addition, existing sheath is fixed by body and elastic ring, there are two types of existing elastic ring production methods, The first is that body opening's edge part is integrally rolled into elastic ring, and second is sticked at by the opening's edge part volume of body open end It is made on prefabricated elastic ring.Wherein, the elastic ring ring diameter in the first production method is difficult to reach expected rugosity, leads to lock ring Power is limited, and causes body consumptive material more;As for second of production method, increase final elastic ring by prefabricated elastic ring Ring diameter increases clamping force, needs prefabricated elastic ring to roll up since body one end viscous, so prefabricated elastic ring is inactive with body 's.Therefore, this field produces technology prejudice: increasing the ring diameter of ring resilience ring by prefabricated elastic ring, prefabricated elastic ring is wrapped Be rolled in set in vivo and be it is non-movable, therefore, life can be realized using common integrally formed elastic ring body in prefabricated elastic ring Produce require, and it is simpler, the lower cost the better.The sheath of above method production and the elastic of elastic ring are not adjustable, the On the one hand cannot reach prevent sheath from sliding and so that the back-flow velocity of penile vein blood is slowed down and reach extension telotism when Between purpose;Second aspect, sheath size select it is improper when, cannot use cause to waste;The third aspect, in sexual intercourse knot Beam or when needing to remove sheath because of thing, elastic ring, which is removed, to be not easy or elastic ring touches penis especially glans penis part and makes At sense of discomfort.
Summary of the invention
It is an object of the present invention to provide a kind of new solutions of anti-inflammatory sheath.
It is an object of the present invention to provide a kind of new solutions of the production method of anti-inflammatory sheath.
According to the first aspect of the invention, a kind of anti-inflammatory sheath is provided, including body and set on body open end Elastic ring, spray attachment sheath matrix and Chinese traditional medicine composition on the body, the elastic ring are joined end to end by a linear main body, The cross section of the threadiness main body is circle, and the threadiness main body head end is coaxially arranged with outer pillar, on the outer pillar uniformly Several elastic chip cards are configured with, the threadiness body trailing end is formed with the circular groove with the inserting cooperation of outer pillar, the circular groove Uniformly open up several annular grooves on inner wall, the annular groove with the quantity of chip card, interval is identical and is able to achieve clamping engagement.
Preferably, with the total restatement of sheath, the weight content of the Chinese medicine composition is 1~2%, the Chinese medicine composition Mainly it is prepared by the component of following parts by weight:
5-10 parts of rhizoma polygonati, 4-8 parts of Schisandra chinensis, 6-11 parts of fructus lycii, 3-6 parts of folium artemisiae argyi, 7-9 parts of frutus cnidii, gamboge pericarp 11- 14 parts, 5-8 parts of granatum, 7-11 parts of dandelion, 14-17 parts of Radix Glycyrrhizae, 5-8 parts of coriander.
Preferably, the Chinese medicine composition is prepared by the component of following parts by weight:
7 parts of rhizoma polygonati, 6 parts of Schisandra chinensis, 8 parts of fructus lycii, 5 parts of folium artemisiae argyi, 8 parts of frutus cnidii, 12 parts of gamboge pericarp, 7 parts of granatum, 10 parts of dandelion, 16 parts of Radix Glycyrrhizae, 8 parts of coriander.
Preferably, the Chinese medicine composition the preparation method comprises the following steps:
According to formula ratio weigh rhizoma polygonati, Schisandra chinensis, fructus lycii, folium artemisiae argyi, frutus cnidii, gamboge pericarp, granatum, dandelion, Radix Glycyrrhizae and coriander are uniformly mixed, and extracting in water in extractor is placed in after cleaning and twice, adds 8 times of weights of composition total weight for the first time The water of amount, for the second time plus the water of 6 times of weight of composition total weight, each extraction 2 hours are made medical fluid, medical fluid are filtered, merging The medical fluid decocted twice, when being concentrated under reduced pressure into 60 DEG C relative density be 1.0 medicinal extract, spray drying to get.
According to the second aspect of the invention, a kind of production method of anti-inflammatory sheath is provided, comprising the following steps:
A, the body of previously prepared sheath out, and body is propped up with prefabricated mould;
B, pulling-down adjusts elastic ring size and is allowed to be adapted to body, and elasticity is located on the opening's edge close to sheath open end On partial mold;
C, in the opening's edge part coated with adhesive of body open end, wherein adhesive coated position is at a distance of body open end Distance be equal to the perimeter of linear main body, scrolling opening's edge part makes elastic ring by winding in the opening's edge part of open end;
D, rolls forward elastic ring is bonded body by adhesive, then rolls to demoulding;
E, by Chinese medicine composition stirring in sheath matrix, spray attachment is packed after sheath.
Anti-inflammatory sheath of the invention overcomes technology prejudice, and the elastic of elastic ring can be adjusted as needed, elastic ring It is mobilizable in vivo to facilitate adjusting in set, outer pillar and circular groove plug conveniently, and annular groove is easy in conjunction with chip card It is easy to adjust;In a first aspect, in sexual intercourse adjustable elastic ring clamping force, can reach prevents sheath from sliding and keeps penis quiet The back-flow velocity of arteries and veins blood slow down and reach extend the telotism time purpose, promote telotism obtain it is thicker, longer, more hold Long, more strong;Second aspect can be adjusted elastic by elastic ring, avoid wave when sheath size selects improper Take;The third aspect, when sexual intercourse terminates or needs to remove sheath because of thing, elastic ring can amplify, and therefore, remove conveniently, can It avoids elastic ring from touching penis especially glans penis part and causes sense of discomfort.The production method of anti-inflammatory sheath of the invention is simply square Just, it is only necessary to elastic ring structure be improved, do not change original condom manufacture process substantially, but bring unexpected Using effect.Chinese medicine composition reasonable recipe of the present invention, meets traditional Chinese medical theory, is added in sheath, can Effectively to treat inflammation, health is ensured.
By referring to the drawings to the detailed description of exemplary embodiment of the present invention, other feature of the invention and its Advantage will become apparent.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of elastic ring provided by the invention;
Fig. 2 is the schematic diagram of step a in the production method of anti-inflammatory sheath provided by the invention;
Fig. 3 is the schematic diagram of step b in the production method of anti-inflammatory sheath provided by the invention;
Fig. 4 is the schematic diagram of step c in the production method of anti-inflammatory sheath provided by the invention;
Fig. 5 is the schematic diagram of step d in the production method of anti-inflammatory sheath provided by the invention.
Specific embodiment
Carry out the various exemplary embodiments of detailed description of the present invention now with reference to attached drawing.It should also be noted that unless in addition having Body explanation, the unlimited system of component and the positioned opposite of step, numerical expression and the numerical value otherwise illustrated in these embodiments is originally The range of invention.
Be to the description only actually of at least one exemplary embodiment below it is illustrative, never as to the present invention And its application or any restrictions used.
Technology and equipment known to person of ordinary skill in the relevant may be not discussed in detail, but in appropriate situation Under, the technology and equipment should be considered as part of specification.
It is shown here and discuss all examples in, any occurrence should be construed as merely illustratively, without It is as limitation.Therefore, other examples of exemplary embodiment can have different values.
It should also be noted that similar label and letter indicate similar terms in following attached drawing, therefore, once a certain Xiang Yi It is defined in a attached drawing, then in subsequent attached drawing does not need that it is further discussed.
It should be noted that the positional terms such as initial and end in the embodiment of the present invention, forward and backward, intermediate, left and right, upper and lower, It is only relative concept or be reference with the normal operating condition of product each other, and should not be regarded as restrictive.
With reference to Fig. 1-Fig. 5, the embodiment of the invention provides a kind of anti-inflammatory sheaths.
The anti-inflammatory sheath includes body 1 and the elastic ring 2 set on 1 open end of body, spray attachment sheath on the body 1 Matrix and Chinese traditional medicine composition, the elastic ring 2 are joined end to end by a linear main body 21, and the cross section of the threadiness main body 21 is Circle, threadiness 21 head end of main body are coaxially arranged with outer pillar 22, and outer pillar 22 is formed on linear 21 head end end face of main body, Outer pillar 22 is integrally formed with linear main body 21, and massiveness has several elastic chip cards 221, elasticity on the outer pillar 22 Chip card 221 and outer 22 Construction integration of pillar, elastic chip card 221 are coaxially disposed with outer pillar 22.And linear main body 21 Tail end is formed with the circular groove 23 with the inserting cooperation of outer pillar 22, and the depth of circular groove 23 is identical as outer 22 length of pillar, 23 quilt of circular groove It is configured to protrude into inside linear main body 21 from tail end end face, several annular grooves 231 is uniformly opened up on 23 inner wall of circular groove, annular Slot 231 is formed along circular groove 23 is circumferential, and the annular groove 23 is matched with 221 shape of chip card, and the quantity of the two, be spaced it is identical And it is able to achieve clamping engagement.Annular groove 231 is combined with chip card 221 is easy easy to adjust, outer pillar 22 and the use of circular groove 23 Above-mentioned special construction, it is ensured that it is convenient that outer pillar 22 is plugged with circular groove 23, convenient when 2 big minor adjustment of elastic ring.
The embodiment of the invention provides a kind of production methods of anti-inflammatory sheath, comprising the following steps:
A, it is previously prepared go out sheath body 1 and body 1 is propped up with prefabricated mould.
B, pulling-down adjusts 2 size of elastic ring and is allowed to be adapted to body 1, and elastic ring 2 is placed on close to sheath open end On the mold of opening's edge part 3;It should be noted that should be guaranteed that be adapted to body 1 elastic ring 2 be in can pulling-down state, i.e., it is outer 22 part of pillar is plugged in circular groove 23, so later in use, can according to need the elastic ring tune pine of sheath or Person tightens.
C, in 3 coated with adhesive 4 of opening's edge part of 1 open end of body, wherein it is spacious at a distance of body 1 that adhesive 4 coats position The distance at mouth end is equal to the perimeter of linear main body 21, and scrolling opening's edge part 3 makes elastic ring 2 by winding in the opening's edge part of open end In 3.
D, rolls forward elastic ring 2 is bonded body 1 by adhesive 4, then rolls to demoulding;
E, by Chinese medicine composition stirring in sheath matrix, spray attachment is packed after sheath.
Anti-inflammatory sheath of the invention overcomes technology prejudice, and the elastic of elastic ring can be adjusted as needed, elastic ring Mobilizable in vivo to by body elastic ring be adjusted in set, outer pillar and circular groove plug conveniently, annular groove and Chip card combination is easy easy to adjust;In a first aspect, in sexual intercourse adjustable elastic ring clamping force, can reach prevents from practising contraception Set slides and so that the back-flow velocity of penile vein blood is slowed down and reach the purpose of extension telotism time, and telotism is promoted to obtain It is thicker, longer, more longlasting, more strong;Second aspect can be adjusted when sheath size selects improper by elastic ring It saves elastic, avoids wasting;The third aspect, when sexual intercourse terminates or needs to remove sheath because of thing, elastic ring can amplify, because This is removed conveniently, and avoidable elastic ring touches penis especially glans penis part and causes sense of discomfort.Anti-inflammatory sheath of the invention Production method is simple and convenient, it is only necessary to improve to elastic ring structure, not change original condom manufacture process substantially, but band Unexpected using effect is carried out.Chinese medicine composition reasonable recipe of the present invention, meets traditional Chinese medical theory, is added In sheath, inflammation can be effectively treated, ensures health.
Embodiment 1
The above-mentioned Chinese medicine composition of the present invention is prepared by the component of following weight grams:
Rhizoma polygonati 7g, Schisandra chinensis 6g, fructus lycii 8g, folium artemisiae argyi 5g, frutus cnidii 8g, gamboge pericarp 12g, granatum 7g, dandelion 10g, Radix Glycyrrhizae 16g, coriander 8g.
Wherein, Chinese medicine composition the preparation method comprises the following steps:
According to formula ratio weigh rhizoma polygonati, Schisandra chinensis, fructus lycii, folium artemisiae argyi, frutus cnidii, gamboge pericarp, granatum, dandelion, Radix Glycyrrhizae and coriander are uniformly mixed, and extracting in water in extractor is placed in after cleaning and twice, adds 8 times of weights of composition total weight for the first time The water of amount, for the second time plus the water of 6 times of weight of composition total weight, each extraction 2 hours are made medical fluid, medical fluid are filtered, merging The medical fluid decocted twice, when being concentrated under reduced pressure into 60 DEG C relative density be 1.0 medicinal extract, spray drying to get.
Embodiment 2
The above-mentioned Chinese medicine composition of the present invention is prepared by the component of following weight grams:
Rhizoma polygonati 5g, Schisandra chinensis 4g, fructus lycii 6g, folium artemisiae argyi 3g, frutus cnidii 7g, gamboge pericarp 11g, granatum 5g, dandelion 7g, Radix Glycyrrhizae 14g, coriander 5g.
Wherein, the preparation method is the same as that of Example 1 for Chinese medicine composition.
Embodiment 3
The above-mentioned Chinese medicine composition of the present invention is prepared by the component of following weight grams:
Rhizoma polygonati 10g, Schisandra chinensis 8g, fructus lycii 11g, folium artemisiae argyi 6g, frutus cnidii 9g, gamboge pericarp 14g, granatum 8g, Pu Gong English 11g, Radix Glycyrrhizae 17g, coriander 8g.
Wherein, the preparation method is the same as that of Example 1 for Chinese medicine composition.
Comparative example 1
The above-mentioned Chinese medicine composition of the present invention is prepared by the component of following weight grams:
Rhizoma polygonati 7g, Schisandra chinensis 6g, fructus lycii 8g, folium artemisiae argyi 5g, granatum 7g, dandelion 10g, Radix Glycyrrhizae 16g, coriander 8g.
Wherein, the preparation method is the same as that of Example 1 for Chinese medicine composition.
Comparative example 2
The above-mentioned Chinese medicine composition of the present invention is prepared by the component of following weight grams:
Rhizoma polygonati 7g, Schisandra chinensis 6g, fructus lycii 8g, folium artemisiae argyi 5g, frutus cnidii 8g, gamboge pericarp 12g, granatum 7g, dandelion 10g, Radix Glycyrrhizae 16g, coriander 8g, oldenlandia diffusa 10g, cloves 10g, asarum 8g.
Wherein, the preparation method is the same as that of Example 1 for Chinese medicine composition.
Comparative example 3
The above-mentioned Chinese medicine composition of the present invention is prepared by the component of following weight grams:
Rhizoma polygonati 7g, Schisandra chinensis 6g, fructus lycii 8g, cloves 10g, frutus cnidii 8g, gamboge pericarp 12g, oldenlandia diffusa 10g, dandelion 10g, Radix Glycyrrhizae 16g, coriander 8g.
Wherein, the preparation method is the same as that of Example 1 for Chinese medicine composition.
Comparative example 4
The above-mentioned Chinese medicine composition of the present invention is prepared by the component of following weight grams:
Rhizoma polygonati 5g, Schisandra chinensis 4g, fructus lycii 6g, folium artemisiae argyi 13g, frutus cnidii 7g, gamboge pericarp 21g, granatum 5g, dandelion 17g, Radix Glycyrrhizae 14g, coriander 5g.
Wherein, the preparation method is the same as that of Example 1 for Chinese medicine composition.
Comparative example 5
The above-mentioned Chinese medicine composition of the present invention is prepared by the component of following weight grams:
Rhizoma polygonati 1g, Schisandra chinensis 8g, fructus lycii 11g, folium artemisiae argyi 6g, frutus cnidii 9g, gamboge pericarp 2g, granatum 8g, dandelion 11g, Radix Glycyrrhizae 3g, coriander 8g.
Wherein, the preparation method is the same as that of Example 1 for Chinese medicine composition.
Test example antiphlogistic effects compare
Test method: it chooses 130 200-250 grams of weight of male rat and is divided into test 1-3 group, control 1-5 group, the positive Medicine group and blank group, are stopped eating 15-16 hours, but do not cut off the water before experiment by every group 10, after random grouping, test 1-3 group rat Stomach-filling is carried out with the composition of embodiment 1-3 respectively, control 1-5 group carries out stomach-filling using the composition of reference examples 1-5, tests 1- 3 groups are 18mg/kg/ days with control 1-5 group gastric infusion amount, positive drug group Pudilan sulfathiazole stomach-filling, and blank group is given etc. The distilled water of amount, continuous gavage are administered 7 days, and 30min, is coated with dimethylbenzene on mouse right ear two sides respectively after the last administration Only, left ear compares 0.05ml/, and animal is put to death after 15min, cuts ears with position with the punch of diameter 6mm, uses electronics Balance load-bearing, it is only poor for swelling with left and right auricle weight, each group swelling is calculated, the results are shown in Table 1.
Inhibitory effect of each composition of table 1 to inflammation
Conclusion: by upper table 1 it is found that the Chinese medicine composition of 1-3 of the embodiment of the present invention is above pair the therapeutic effect of inflammation The Chinese medicine composition of 1-5 as usual, it was demonstrated that Chinese medicine composition provided by the invention has a good effect inflammation, when the present invention mentions When group drug dispensing in the Chinese medicine composition of confession increases, reduces or be replaced by other group of drug dispensing, the Chinese medicine composition is to inflammation Therapeutic effect significantly reduces.
Clinical trial
1, test method: enter the observation on probation of case 200, group women chronic pelvic inflammatory disease gynaecology.Age 18-40 years old;
2, treatment method: sheath made from the embodiment of the present invention 1 is used.It uses within one week 2~5 times, one month is one The course for the treatment of.
3, efficacy evaluation:
1. recovery from illness: symptom, sign and inspection restore normal;
2. effective: symptom disappears, and gynecologial examination has clear improvement;
3. effectively: symptom, sign and inspection have mitigation;
4. invalid: without improvement after treatment.
4, treatment results see the table below 2
Finally it should be noted that the above examples are only used to illustrate the technical scheme of the present invention and are not limiting, although reference Preferred embodiment describes the invention in detail, those skilled in the art should understand that, it can be to of the invention Technical solution is modified or replaced equivalently, and without departing from the spirit and scope of the technical solution of the present invention, should all be covered In scope of the presently claimed invention.

Claims (5)

1. a kind of anti-inflammatory sheath, which is characterized in that the elastic ring including body and set on body open end sprays on the body Attached sheath matrix and Chinese traditional medicine composition, the elastic ring are joined end to end by a linear main body, the threadiness main body it is transversal Face is circle, and the threadiness main body head end is coaxially arranged with outer pillar, and massiveness has several elasticity round on the outer pillar Card, the threadiness body trailing end are formed with the circular groove with the inserting cooperation of outer pillar, uniformly open up on the circular groove inner wall several Annular groove, the annular groove with the quantity of chip card, interval is identical and is able to achieve clamping engagement.
2. anti-inflammatory sheath according to claim 1, it is characterised in that: with the total restatement of sheath, the Chinese medicine composition Weight content be 1~2%, the Chinese medicine composition is mainly prepared by the component of following parts by weight:
5-10 parts of rhizoma polygonati, 4-8 parts of Schisandra chinensis, 6-11 parts of fructus lycii, 3-6 parts of folium artemisiae argyi, 7-9 parts of frutus cnidii, gamboge pericarp 11-14 Part, 5-8 parts of granatum, 7-11 parts of dandelion, 14-17 parts of Radix Glycyrrhizae, 5-8 parts of coriander.
3. anti-inflammatory sheath according to claim 2, which is characterized in that the Chinese medicine composition by following parts by weight group Divide and be prepared:
7 parts of rhizoma polygonati, 6 parts of Schisandra chinensis, 8 parts of fructus lycii, 5 parts of folium artemisiae argyi, 8 parts of frutus cnidii, 12 parts of gamboge pericarp, 7 parts of granatum, Pu Gong 10 parts of English, 16 parts of Radix Glycyrrhizae, 8 parts of coriander.
4. anti-inflammatory sheath according to claim 2, which is characterized in that the Chinese medicine composition the preparation method comprises the following steps:
Rhizoma polygonati, Schisandra chinensis, fructus lycii, folium artemisiae argyi, frutus cnidii, gamboge pericarp, granatum, dandelion, Radix Glycyrrhizae are weighed according to formula ratio It is uniformly mixed with coriander, extracting in water in extractor is placed in after cleaning and twice, adds 8 times of weight of composition total weight for the first time Water, for the second time plus the water of 6 times of weight of composition total weight, each extraction 2 hours are made medical fluid, medical fluid are filtered, and merging is twice The medical fluid of decoction, when being concentrated under reduced pressure into 60 DEG C relative density be 1.0 medicinal extract, spray drying to get.
5. a kind of production method of anti-inflammatory sheath according to any one of claims 1-4, it is characterised in that: including following step It is rapid:
A, the body of previously prepared sheath out, and body is propped up with prefabricated mould;
B, pulling-down adjusts elastic ring size and is allowed to be adapted to body, and elasticity is located on to the opening's edge part close to sheath open end Mold on;
C, in the opening's edge part coated with adhesive of body open end, wherein adhesive coated position at a distance of body open end away from From the perimeter for being equal to linear main body, scrolling opening's edge part makes elastic ring by winding in the opening's edge part of open end;
D, rolls forward elastic ring is bonded body by adhesive, then rolls to demoulding;
E, by Chinese medicine composition stirring in sheath matrix, spray attachment is packed after sheath.
CN201810726745.4A 2018-07-04 2018-07-04 Anti-inflammatory condom and production method thereof Active CN109044599B (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5803085A (en) * 1996-06-11 1998-09-08 Asinovsky; Vladimir A. Non-elastic condom
CN1686063A (en) * 2005-04-06 2005-10-26 吕慎忠 New type condom
CN201469487U (en) * 2009-09-01 2010-05-19 俞江虚 Anti-slip condom
CN103445902A (en) * 2013-09-25 2013-12-18 桂林恒保健康用品有限公司 Condom capable of treating gynecological diseases and production method thereof
CN204016589U (en) * 2013-09-02 2014-12-17 宁小静 Condom
KR20180022319A (en) * 2016-08-24 2018-03-06 이준민 Pressure controlled ring for penis constriction

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5803085A (en) * 1996-06-11 1998-09-08 Asinovsky; Vladimir A. Non-elastic condom
CN1686063A (en) * 2005-04-06 2005-10-26 吕慎忠 New type condom
CN201469487U (en) * 2009-09-01 2010-05-19 俞江虚 Anti-slip condom
CN204016589U (en) * 2013-09-02 2014-12-17 宁小静 Condom
CN103445902A (en) * 2013-09-25 2013-12-18 桂林恒保健康用品有限公司 Condom capable of treating gynecological diseases and production method thereof
KR20180022319A (en) * 2016-08-24 2018-03-06 이준민 Pressure controlled ring for penis constriction

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