CN108991246A - A kind of functional form additive for farm animal feed and the preparation method and application thereof - Google Patents
A kind of functional form additive for farm animal feed and the preparation method and application thereof Download PDFInfo
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- CN108991246A CN108991246A CN201810857996.6A CN201810857996A CN108991246A CN 108991246 A CN108991246 A CN 108991246A CN 201810857996 A CN201810857996 A CN 201810857996A CN 108991246 A CN108991246 A CN 108991246A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
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Abstract
Be made of the raw material of following parts by weight the invention discloses a kind of functional form additive for farm animal feed: 2-10 parts of phytosterol, 1-5 parts of Cineole, 1-5 parts of paddy sweet Guang peptide, 1-5 parts of nicotinate chromium, 2-10 parts of lysine, 1-5 parts of methionine, 5-15 parts of sodium bicarbonate, 10-20 parts of surface modification carrier, glucoside are vitamin A 5-10 parts modified.The invention also discloses the preparation methods and application of the functional form additive for farm animal feed.Functional form additive for farm animal feed disclosed by the invention has the advantages that promote production performance (feed intake, weight gain, feed conversion rate), improves anti-stress ability, enhancing immune function, improves meat.
Description
Technical field
The present invention relates to field of feed additive technology more particularly to a kind of functional form additive for farm animal feed and its preparations
Method and application.
Background technique
In recent years, with the continuous improvement of social progress and living standards of the people, fast food restaurant's quantity is increasing, people
Demand to carnivorous is also increasing, so that animal husbandry development is swift and violent.The herding benefiting from modern farming enterprise's technology and developing rapidly
Industry is to ensure that the vegetable basket demand of the people has established solid foundation.But environment, disease under intensive dense husbandry mode
Caused various stress damages, usually jeopardize livestock birds health and its normal productive process, this has become with trophic factor stimulation
China's sustainable development of animal husbandry conspicuous contradiction urgently to be resolved.
The raising of fowl poultry kind animal be unable to do without feed, and high, vdiverse in function, the cheap feed of exploitation nutritive value is solution
Certainly one of this contradictory beneficial pathways, however the feed of the prior art usually contains hormone substance, has an impact to poultry, into
One step influences the health of people, and some feed formulas are unreasonable, and nutritional ingredient is very few, poultry slow growth.It needs to add in feed
Add additive for farm animal feed and is good for improve the nutritive value of feed, improve efficiency of feed utilization, promotion animal productiong, enhancement animal
Health improves livestock products quality, improves breeding performonce fo animals, reduces production cost.
Additive for farm animal feed currently used in the market is mostly such as antibiotic, somatotropin, hormone, preservative, flavoring agent
Etc. the medicinal mixture having a single function, not only effect is low, and resulting medicament residue easily leads to serious food peace
Complete and environmental problem.Excessive antibiotic and medicated premix are used in feed, are not only resulted in pathogenic bacteria and are generated drug resistance, and
And the drug remained in animal products can induce the change of human DNA structure, cause " teratogenesis ", " disabling ", " carcinogenic " etc. tight
Weight consequence, the internal residual quantity that feed addictive brings animal product is excessively high and the risk of human diseases is caused to increase, especially
It is that the additions of some human somatotropic hormones being restricted and noxious material is easier to cause the fear of consumer, in animal meat products
Hormone, antibiotic etc residual have become serious food safety and hygienic issues, this is not only related to the strong of aquaculture
Kang Fazhan is also directly related to the physical and mental health, social stability and development of the mankind.
Therefore, in conjunction with livestock and poultry physilogical characteristics, the functional form animal and fowl fodder for having green, high efficiency and low cost feature is developed
Additive has extensive market prospects and application value, is livestock and poultry nutritional intervention technical research in modern farming enterprise's aquaculture
With the key point of popularization.
Summary of the invention
The main purpose of the present invention is to provide a kind of functional form additive for farm animal feed and the preparation method and application thereof, should
Preparation method is easy to operation, of less demanding to equipment and reaction condition, and required raw material and equipment are easy to get, the function being prepared
Energy type additive for farm animal feed is widely used, and is had and is promoted production performance (feed intake, weight gain, feed conversion rate), improves anti-answer
The ability of swashing, improves the advantages of meat at enhancing immune function.
To achieve the above objectives, the technical solution adopted by the present invention are as follows: a kind of functional form additive for farm animal feed, is by such as
Made of the raw material of lower parts by weight: 2-10 parts of phytosterol, 1-5 parts of Cineole, 1-5 parts of paddy sweet Guang peptide, 1-5 parts of nicotinate chromium,
The modified dimension life of 2-10 parts of lysine, 1-5 parts of methionine, 5-15 parts of sodium bicarbonate, 10-20 parts of surface modification carrier, glucoside
Plain A 5-10 parts.
Preferably, the preparation method of the surface modification carrier, includes the following steps:
Support dispersion is formed dispersion liquid by I in organic solvent, then bis- [3- (triethoxysilicane) propyl] amine are added thereto,
Be stirred to react at 40-50 DEG C 4-6 hours, after eight (6- bromo- 6- deoxidation)-gamma-cyclodextrins are added thereto again, at 60-80 DEG C
It is stirred to react 6-8 hours, it is rear to filter, and washed 3-5 time with ethyl alcohol, then to be placed in a vacuum drying oven baking 10-15 at 70-80 DEG C small
When, obtain intermediate product；
II is immersed in the intermediate product being prepared by step I the aqueous solution for the sodium gluconate that mass fraction is 5-10%
30-50 hours middle, rear take out is immersed in again in the copper chloride solution that mass fraction is 1-3%, is filtered, then be placed in vacuum oven
It is dried 10-15 hours at middle 90-100 DEG C, obtains surface modification carrier.
Further, carrier described in step I, organic solvent, bis- [3- (triethoxysilicane) propyl] amine, eight (the bromo- 6- of 6-
Deoxidation)-gamma-cyclodextrin mass ratio be (3-5): (10-15): 1:1.1.
Preferably, the carrier is selected from hydroxyapatite nano-structure hollow pipe, calcium carbonate nano structure hollow sphere, porous
One or more of silicon dioxide microsphere.
Preferably, the hydroxyapatite nano-structure hollow pipe, calcium carbonate nano structure hollow sphere are previously prepared, system
Preparation Method reference: Zhang Xiaojing, the preparation and medicament slow release performance research of biocompatibility hollow nano-material, Hefei industry
University, 2012.
Preferably, the organic solvent is selected from one or more of isopropanol, acetone, methylene chloride, tetrahydrofuran.
Further, intermediate product described in step II, the aqueous solution of sodium gluconate, copper chloride solution mass ratio be
1:(10-20):(5-10)。
Preferably, the preparation method of the modified vitamin A of the glucoside, includes the following steps: in nitrogen or indifferent gas
Under body atmosphere, trans--zeatin -9-B- glucoside and vitamin A are added to equipped with reflux condensing tube, electric mixer
In there-necked flask, then isopropanol being added into bottle, flows back and be stirred to react 3-5 hours at 110-120 DEG C, solvent is evaporated off in back spin,
Obtain the modified vitamin A of glucoside.
Preferably, the trans--zeatin -9-B- glucoside, vitamin A, isopropanol mass ratio be 1:(4-5):
(15-20)。
Preferably, the inert gas is selected from one or more of helium, neon, argon gas.
Preferably, the preparation method of the functional form additive for farm animal feed, includes the following steps: each raw material in proportion
Mixing, after with 600-800 rev/min speed stirring 1-3 hours, using mill, be sieved, pack after obtain functional form livestock and poultry
Feed additives products.
Preferably, the application of the functional form additive for farm animal feed includes the following steps: to raise the functional form livestock and poultry
Feed additives in mass ratio 1% are added in animal and fowl fodder, with 800-1000 rev/min speed stirring 0.5-1 hours, then are passed through
It crosses and mills, is sieved, packing.
Due to the above technical solutions, the present invention has the following advantages over the prior art:
(1) functional form additive for farm animal feed provided by the invention, preparation method is easy to operation, to equipment and reaction condition
Of less demanding, required raw material and equipment are easy to get, and are suitble to large-scale production.
(2) functional form additive for farm animal feed provided by the invention overcomes traditional additive for farm animal feed and has a single function
Medicinal mixture, not only effect is low, and resulting medicament residue easily leads to serious food safety and environment is asked
The defect of topic, have be widely used, can promote production performance (feed intake, weight gain, feed conversion rate), improve anti-stress ability,
Enhance immune function, improve the advantages of meat, there are preferable economic benefit, social benefit and ecological benefits.
(3) functional form additive for farm animal feed provided by the invention introduces porous or hollow nano-material and carries as controlled release
Body, specific surface area with higher and strong adsorption desorption force characteristic, stability is high, cheap, nontoxic, good biocompatibility, leads to
It is cyclodextrin modified to cross surface, introduces quaternary ammonium salt structure, has to Escherichia coli, salmonella typhi and staphylococcus aureus etc.
Good antibacterial action can effectively inhibit animal and bird intestines harmful bacteria to be proliferated, and improve intestinal microecology, improve villi height and intestines
Mucosal barrier function, the digestion of secretion and feed nutrient beneficial to digestive ferment promote animal and bird intestines health, livestock and poultry can be improved and survive
Rate and production performance improve surface property, improve dispersibility and compatibility, and improve stability.
(4) functional form additive for farm animal feed provided by the invention is free of antibiotic and hormone, adjusts ring in livestock and poultry body
Border is established and is maintained archenteric flora balance, improves animal immunizing power.
(5) functional form additive for farm animal feed provided by the invention, the battalion such as copper rich in, chromium, protein, vitamin
It forms point, livestock and poultry can be helped to supplement nutrition abundant, beneficial to its fast-growth and breeding.
Specific embodiment
It is described below for disclosing the present invention so that those skilled in the art can be realized the present invention.It is excellent in being described below
Embodiment is selected to be only used as illustrating, it may occur to persons skilled in the art that other obvious modifications.
Hydroxyapatite nano-structure hollow pipe described in embodiment, calcium carbonate nano structure hollow sphere be it is previously prepared,
Preparation method reference: Zhang Xiaojing, the preparation and medicament slow release performance research of biocompatibility hollow nano-material, Hefei work
Sparetime university is learned, and 2012, porous silica microballoon is purchased from Xi'an Rui Xi Biotechnology Co., Ltd, other raw materials are purchased from traditional Chinese medicines group
Reagent Co., Ltd.
Embodiment 1
A kind of functional form additive for farm animal feed is made of the raw material of following parts by weight: 2 parts of phytosterol, Cineole 1
Part, 1 part of the sweet Guang peptide of paddy, 1 part of nicotinate chromium, 2 parts of lysine, 1 part of methionine, 5 parts of sodium bicarbonate, surface modification hydroxyapatite
Modified 5 parts of the vitamin A of 10 parts of nanostructure hollow pipe, glucoside.
The preparation method of the surface modification hydroxyapatite nano-structure hollow pipe, includes the following steps:
I disperses hydroxyapatite nano-structure hollow pipe 30g in isopropanol 100g and forms dispersion liquid, then is added thereto double
[3- (triethoxysilicane) propyl] amine 10g, is stirred to react 4 hours at 40 DEG C, after be added that eight (the bromo- 6- of 6- is gone thereto again
Oxygen)-gamma-cyclodextrin 11g, it is stirred to react at 60 DEG C 6 hours, it is rear to filter, and washed 3 times with ethyl alcohol, then be placed in vacuum oven
In dry 10 hours at 70 DEG C, obtain intermediate product；
II is immersed in the intermediate product 10g being prepared by step I the aqueous solution for the sodium gluconate that mass fraction is 5%
30 hours in 100g, rear take out is immersed in again in the copper chloride solution 50g that mass fraction is 1%, is filtered, then be placed in vacuum drying
It is dried 10 hours at 90 DEG C in case, obtains surface modification carrier.
The preparation method of the modified vitamin A of the glucoside, includes the following steps: under nitrogen atmosphere, will trans--jade
Meter Su -9-B- glucoside 10g and vitamin A 40g be added to equipped with reflux condensing tube, electric mixer there-necked flask in, then
Isopropanol 150g is added into bottle, flows back and is stirred to react 3 hours at 110 DEG C, solvent is evaporated off in back spin, obtains glucoside and changes
Property vitamin A.
The preparation method of the functional form additive for farm animal feed includes the following steps: in proportion to mix each raw material, after
With 600 rev/min speed stirring 1 hour, using mill, be sieved, pack after obtain functional form additive for farm animal feed at
Product.
Preferably, the application of the functional form additive for farm animal feed includes the following steps: to raise the functional form livestock and poultry
Feed additives in mass ratio 1% are added in animal and fowl fodder, with 800 rev/min speed stirring 0.5 hour, using mill,
Sieving, packaging.
Embodiment 2
A kind of functional form additive for farm animal feed is made of the raw material of following parts by weight: 4 parts of phytosterol, Cineole 2
Part, 2 parts of the sweet Guang peptide of paddy, 2 parts of nicotinate chromium, 4 parts of lysine, 2 parts of methionine, 7 parts of sodium bicarbonate, surface modification calcium carbonate nano knot
Modified 7 parts of the vitamin A of 13 parts of structure hollow sphere, glucoside.
The preparation method of the surface modification calcium carbonate nano structure hollow sphere, includes the following steps:
I disperses calcium carbonate nano structure hollow sphere 35g in acetone 115g and forms dispersion liquid, then bis- [3- (three are added thereto
Ethyoxyl silicon) propyl] amine 10g, be stirred to react at 43 DEG C 4.5 hours, after eight (6- bromo- 6- deoxidation)-γ-are added thereto again
Cyclodextrin 11g is stirred to react 6.5 hours at 65 DEG C, rear to filter, and is washed 4 times with ethyl alcohol, then be placed in a vacuum drying oven 73 DEG C
It is lower to dry 11 hours, obtain intermediate product；
II is immersed in the intermediate product 10g being prepared by step I the aqueous solution for the sodium gluconate that mass fraction is 7%
35 hours in 125g, rear take out is immersed in again in the copper chloride solution 65g that mass fraction is 2%, is filtered, then be placed in vacuum drying
It is dried 12 hours at 93 DEG C in case, obtains surface modification carrier.
The preparation method of the modified vitamin A of the glucoside, includes the following steps: under helium atmosphere, will be trans--beautiful
Meter Su -9-B- glucoside 10g and vitamin A 43g be added to equipped with reflux condensing tube, electric mixer there-necked flask in, then
Isopropanol is added into bottle, flows back and is stirred to react 4 hours at 113 DEG C, solvent is evaporated off in back spin, obtains the modified dimension of glucoside
Raw element A.
The preparation method of the functional form additive for farm animal feed includes the following steps: in proportion to mix each raw material, after
With 650 rev/min speed stirring 1.5 hours, using mill, be sieved, pack after obtain functional form additive for farm animal feed
Finished product.
The application of the functional form additive for farm animal feed includes the following steps: to add the functional form animal and fowl fodder
Agent in mass ratio 1% is added in animal and fowl fodder, with 850 rev/min speed stirring 0.7 hour, using milling, be sieved, wrap
Dress.
Embodiment 3
A kind of functional form additive for farm animal feed is made of the raw material of following parts by weight: 6 parts of phytosterol, Cineole 3
Part, 4 parts of the sweet Guang peptide of paddy, 3 parts of nicotinate chromium, 6 parts of lysine, 3 parts of methionine, 8 parts of sodium bicarbonate, surface modification porous silica
Modified 7 parts of the vitamin A of 16 parts of silicon microballoon, glucoside.
The preparation method of the surface modification porous silica microballoon, includes the following steps:
I disperses porous silica microballoon 40g in methylene chloride 135g and forms dispersion liquid, then bis- [3- (three are added thereto
Ethyoxyl silicon) propyl] amine 10g, be stirred to react at 46 DEG C 5 hours, after eight (6- bromo- 6- deoxidation)-γ-rings are added thereto again
Dextrin 11g is stirred to react 7 hours at 70 DEG C, rear to filter, and is washed 5 times with ethyl alcohol, then be placed in a vacuum drying oven at 76 DEG C and dry
13 hours, obtain intermediate product；
II is immersed in the intermediate product 10g being prepared by step I the aqueous solution for the sodium gluconate that mass fraction is 8%
40 hours in 180g, rear take out is immersed in again in the copper chloride solution 80g that mass fraction is 3%, is filtered, then be placed in vacuum drying
It is dried 13 hours at 96 DEG C in case, obtains surface modification carrier.
The preparation method of the modified vitamin A of the glucoside, includes the following steps: under neon atmosphere, will be trans--beautiful
Meter Su -9-B- glucoside 10g and vitamin A 46g be added to equipped with reflux condensing tube, electric mixer there-necked flask in, then
Isopropanol 180g is added into bottle, flows back and is stirred to react 4.2 hours at 116 DEG C, solvent is evaporated off in back spin, obtains glucoside
Modified vitamin A.
The preparation method of the functional form additive for farm animal feed includes the following steps: in proportion to mix each raw material, after
With 720 rev/min speed stirring 2.2 hours, using mill, be sieved, pack after obtain functional form additive for farm animal feed
Finished product.
Preferably, the application of the functional form additive for farm animal feed includes the following steps: to raise the functional form livestock and poultry
Feed additives in mass ratio 1% are added in animal and fowl fodder, with 910 rev/min speed stirring 0.8 hour, using mill,
Sieving, packaging.
Embodiment 4
A kind of functional form additive for farm animal feed is made of the raw material of following parts by weight: 8 parts of phytosterol, Cineole 4
Part, 5 parts of the sweet Guang peptide of paddy, 4 parts of nicotinate chromium, 9 parts of lysine, 4 parts of methionine, 13 parts of sodium bicarbonate, surface modification carrier 18 part,
Glucoside is modified 7 parts of vitamin A.
The preparation method of the surface modification carrier, includes the following steps:
I disperses carrier 45g in organic solvent 145g and forms dispersion liquid, then bis- [3- (triethoxysilicane) third are added thereto
Base] amine 10g, be stirred to react at 48 DEG C 5.8 hours, after eight (6- bromo- 6- deoxidation)-gamma-cyclodextrin 11g are added thereto again,
It is stirred to react at 78 DEG C 7.7 hours, it is rear to filter, and washed 4 times with ethyl alcohol, then it is placed in a vacuum drying oven at 78 DEG C that dry 14 small
When, obtain intermediate product；The carrier is hydroxyapatite nano-structure hollow pipe, calcium carbonate nano structure hollow sphere, porous
The mixture that silicon dioxide microsphere 1:2:1 in mass ratio is mixed；The organic solvent is isopropanol, acetone, methylene chloride
The mixture that 1:2:3 in mass ratio is mixed；
II is immersed in the intermediate product 10g being prepared by step I the aqueous solution for the sodium gluconate that mass fraction is 9%
47 hours in 185g, rear take out is immersed in again in the copper chloride solution 95g that mass fraction is 3%, is filtered, then be placed in vacuum drying
It is dried 14.5 hours at 98 DEG C in case, obtains surface modification carrier.
The preparation method of the modified vitamin A of the glucoside, includes the following steps: under argon atmosphere, will be trans--beautiful
Meter Su -9-B- glucoside 10g and vitamin A 48g be added to equipped with reflux condensing tube, electric mixer there-necked flask in, then
Isopropanol 190g is added into bottle, flows back and is stirred to react 4.5 hours at 118 DEG C, solvent is evaporated off in back spin, obtains glucoside
Modified vitamin A.
The preparation method of the functional form additive for farm animal feed includes the following steps: in proportion to mix each raw material, after
With 780 rev/min speed stirring 2.8 hours, using mill, be sieved, pack after obtain functional form additive for farm animal feed
Finished product.
The application of the functional form additive for farm animal feed includes the following steps: to add the functional form animal and fowl fodder
Agent in mass ratio 1% is added in animal and fowl fodder, with 950 rev/min speed stirring 0.9 hour, using milling, be sieved, wrap
Dress.
Embodiment 5
A kind of functional form additive for farm animal feed is made of the raw material of following parts by weight: 10 parts of phytosterol, Cineole 5
Part, 5 parts of the sweet Guang peptide of paddy, 5 parts of nicotinate chromium, 10 parts of lysine, 5 parts of methionine, 15 parts of sodium bicarbonate, surface modification hydroxyapatite
Modified 10 parts of the vitamin A of 20 parts of nanostructure hollow pipe, glucoside.
The preparation method of the surface modification hydroxyapatite nano-structure hollow pipe, includes the following steps:
I disperses hydroxyapatite nano-structure hollow pipe 50g in tetrahydrofuran 150g and forms dispersion liquid, then is added thereto
Bis- [3- (triethoxysilicane) propyl] amine 10g, are stirred to react 6 hours at 50 DEG C, after be added that eight (the bromo- 6- of 6- is gone thereto again
Oxygen)-gamma-cyclodextrin 11g, it is stirred to react at 80 DEG C 8 hours, it is rear to filter, and washed 5 times with ethyl alcohol, then be placed in vacuum oven
In dry 15 hours at 80 DEG C, obtain intermediate product；
The intermediate product 10g being prepared by step I is immersed in the water-soluble of sodium gluconate that mass fraction is 10% by II
50 hours in liquid 200g, rear take out is immersed in again in the copper chloride solution 100g that mass fraction is 3%, is filtered, then be placed in vacuum and do
It is dried 15 hours at 100 DEG C in dry case, obtains surface modification carrier.
The preparation method of the modified vitamin A of the glucoside, includes the following steps: under nitrogen atmosphere, will trans--jade
Meter Su -9-B- glucoside 10g and vitamin A 50g be added to equipped with reflux condensing tube, electric mixer there-necked flask in, then
Isopropanol 200g is added into bottle, flows back and is stirred to react 5 hours at 120 DEG C, solvent is evaporated off in back spin, obtains glucoside and changes
Property vitamin A.
The preparation method of the functional form additive for farm animal feed includes the following steps: in proportion to mix each raw material, after
With 800 rev/min speed stirring 3 hours, using mill, be sieved, pack after obtain functional form additive for farm animal feed at
Product.
Preferably, the application of the functional form additive for farm animal feed includes the following steps: to raise the functional form livestock and poultry
Feed additives in mass ratio 1% are added in animal and fowl fodder, with 1000 rev/min speed stirring 1 hour, using mill, mistake
Sieve, packaging.
Comparative example 1
A kind of functional form additive for farm animal feed is similar to Example 1, the difference is that without the modified vitamin of addition glucoside
A。
Comparative example 2
A kind of functional form additive for farm animal feed is similar to Example 1, the difference is that carrier surface is unmodified.
Comparative example 3
A kind of functional form additive for farm animal feed is made according to the formula of 107712413 A embodiment 1 of CN.
Selection kind is identical, the close healthy weanling pig 450 of weight, is transferred in nursery house and normally raises 3 days, in this phase
Between carry out expelling parasite and epidemic prevention, drinking-water is freely eaten.After 4 days 450 sodium selenites are divided into 9 groups at random, are denoted as this hair respectively
Bright embodiment 1-5, comparative example 1-3, control group, each group of 50 pigs.100kg is added in 1kg additive of livestock and poultry respectively in test
Addition is fed in feed, control group does not add any additive, raises by normal method.The feed is purchased from the honest feeding in Yuanyang County
Expect Co., Ltd；When from on-test, the feed intake of each group pig, Gain weight, food conversion situation etc. are recorded in detail
And it statisticallys analyze.
Table 1
| Group | Average weight increasing a day/g | Equal feed intake/the g of sun | Feedstuff-meat ratio |
| Embodiment 1 | 490.5 | 650.2 | 1.32 |
| Embodiment 2 | 499.7 | 655.4 | 1.31 |
| Embodiment 3 | 518.9 | 659.1 | 1.27 |
| Embodiment 4 | 532.5 | 663.6 | 1.25 |
| Embodiment 5 | 544.8 | 665.0 | 1.22 |
| Comparative example 1 | 470.2 | 680.5 | 1.45 |
| Comparative example 2 | 467.4 | 684.7 | 1.47 |
| Comparative example 3 | 455.6 | 680.2 | 1.49 |
| Control group | 401.4 | 658.3 | 1.64 |
As seen from Table 1, additive for farm animal feed of the embodiment of the present invention is pig after 1% additive amount is added in feed with mass fraction
Average weight increasing a day 490.5-544.8g, sun equal feed intake 650.2-665.0g, feedstuff-meat ratio 1.32-1.22；Without adding additive
Control group pig Average weight increasing a day 401.4g, the equal feed intake 658.3g of sun, feedstuff-meat ratio 1.64；The modified dimension of glucoside is not added
Pig Average weight increasing a day 470.2g when raw element A, the equal feed intake 680.5g of sun, feedstuff-meat ratio 1.45；Pig is average daily when carrier surface is unmodified
Increase weight 467.4g, the equal feed intake 684.7g of sun, feedstuff-meat ratio 1.47, comparative example pig Average weight increasing a day 455.6g in the prior art,
The equal feed intake 680.2g of sun, feedstuff-meat ratio 1.49；As it can be seen that additive for farm animal feed disclosed by the embodiments of the present invention can be mentioned more effectively
High pig production performance, and be conducive to improve pig productivity by the modified vitamin A of addition glucoside and surface modification carrier
Energy.
The basic principles, main features and advantages of the present invention have been shown and described above.The technology of the industry
Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and what is described in the above embodiment and the description is only the present invention
Principle, various changes and improvements may be made to the invention without departing from the spirit and scope of the present invention, these variation and
Improvement is both fallen in the range of claimed invention.The present invention claims protection scope by appended claims and its
Equivalent defines.
Claims (10)
1. a kind of functional form additive for farm animal feed, which is characterized in that be made of the raw material of following parts by weight: phytosterol
2-10 parts, 1-5 parts of Cineole, 1-5 parts of paddy sweet Guang peptide, 1-5 parts of nicotinate chromium, 2-10 parts of lysine, 1-5 parts of methionine, bicarbonate
5-15 parts of sodium, 10-20 parts of surface modification carrier, glucoside are vitamin A 5-10 parts modified.
2. functional form additive for farm animal feed according to claim 1, which is characterized in that the system of the surface modification carrier
Preparation Method includes the following steps:
Support dispersion is formed dispersion liquid by I in organic solvent, then bis- [3- (triethoxysilicane) propyl] amine are added thereto,
Be stirred to react at 40-50 DEG C 4-6 hours, after eight (6- bromo- 6- deoxidation)-gamma-cyclodextrins are added thereto again, at 60-80 DEG C
It is stirred to react 6-8 hours, it is rear to filter, and washed 3-5 time with ethyl alcohol, then to be placed in a vacuum drying oven baking 10-15 at 70-80 DEG C small
When, obtain intermediate product；
II is immersed in the intermediate product being prepared by step I the aqueous solution for the sodium gluconate that mass fraction is 5-10%
30-50 hours middle, rear take out is immersed in again in the copper chloride solution that mass fraction is 1-3%, is filtered, then be placed in vacuum oven
It is dried 10-15 hours at middle 90-100 DEG C, obtains surface modification carrier.
3. functional form additive for farm animal feed according to claim 2, which is characterized in that carrier described in step I, organic
Solvent, bis- [3- (triethoxysilicane) propyl] amine, eight (6- bromo- 6- deoxidation)-gamma-cyclodextrins mass ratio be (3-5): (10-
15):1:1.1。
4. functional form additive for farm animal feed according to claim 2, which is characterized in that the carrier is selected from hydroxy-apatite
One or more of stone nanostructure hollow pipe, calcium carbonate nano structure hollow sphere, porous silica microballoon.
5. functional form additive for farm animal feed according to claim 2, which is characterized in that the organic solvent is selected from isopropyl
One or more of alcohol, acetone, methylene chloride, tetrahydrofuran；Intermediate product described in step II, sodium gluconate it is water-soluble
Liquid, copper chloride solution mass ratio be 1:(10-20): (5-10).
6. functional form additive for farm animal feed according to claim 1, which is characterized in that the modified dimension life of the glucoside
The preparation method of plain A includes the following steps: under nitrogen or atmosphere of inert gases, by trans--zeatin -9-B- glucoside
With vitamin A be added to equipped with reflux condensing tube, electric mixer there-necked flask in, then isopropanol is added into bottle, in 110-
Reflux is stirred to react 3-5 hours at 120 DEG C, and solvent is evaporated off in back spin, obtains the modified vitamin A of glucoside.
7. functional form additive for farm animal feed according to claim 6, which is characterized in that the trans--zeatin -9-B-
Glucoside, vitamin A, isopropanol mass ratio be 1:(4-5): (15-20).
8. functional form additive for farm animal feed according to claim 6, which is characterized in that the inert gas is selected from helium
One or more of gas, neon, argon gas.
9. a kind of preparation method of any one of -8 functional form additive for farm animal feed according to claim 1, which is characterized in that
Include the following steps: in proportion to mix each raw material, after with 600-800 rev/min speed stirring 1-3 hours, using stone roller
Functional form additive for farm animal feed finished product is obtained after mill, sieving, packaging.
10. a kind of application of any one of -8 functional form additive for farm animal feed according to claim 1, which is characterized in that packet
Include following steps: the functional form additive for farm animal feed in mass ratio 1% be added in animal and fowl fodder, with 800-1000 turn/
Speed per minute stirs 0.5-1 hours, using milling, be sieved, pack.
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Application publication date: 20181214 |