CN108969528A - Preparing method of plaster for anal intestine treatment - Google Patents
Preparing method of plaster for anal intestine treatment Download PDFInfo
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- CN108969528A CN108969528A CN201811088601.7A CN201811088601A CN108969528A CN 108969528 A CN108969528 A CN 108969528A CN 201811088601 A CN201811088601 A CN 201811088601A CN 108969528 A CN108969528 A CN 108969528A
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- parts
- lotion
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- anal
- plaster
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
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- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention proposes a kind of preparation method of plaster for anal intestine treatment, includes the following steps: step 1: preparing composite material, material includes 1-3 parts of aureomycin hydrochloride, 1-3 parts of albolene, 1-2 parts of paraffin oil, 2-5 parts of metronidazole, 1-2 parts of borneol powder;Step 2: by 2 parts of albolene, 1 part of paraffin oil, 10% pure water is added and is stirred to form lotion, and is heated to 100 DEG C, is then shut off heating device, maintains 2 minutes;Step 3: completely cooling to the lotion in step 2, add 2 parts of aureomycin hydrochloride, 3 parts of metronidazole and 1 part of borneol powder, it is stirred with lotion and stands 30min, then it is dispensed, obtains acne cream finished product, the present invention is for hemorrhoid, perianal abscess and anal fissure good effect, it is quick, short treating period can thoroughly solve patient's slight illness, effect highly significant.
Description
Technical field
The present invention relates to acne cream, in particular to a kind of preparation method of plaster for anal intestine treatment.
Background technique
Hemorrhoid (being commonly called as hemorrhoid) are a kind of common diseases positioned at anus area, and any age can all fall ill, but with the age
Increase, disease incidence gradually increases.In China, hemorrhoid are the most common anorectal diseases.
Perianal abscess, also known as perianorecrtal abscess, Chinese medicine are known as anus carbuncle.Perianal abscess is to betide anus, anal canal
With periproctic acute suppuration infectious diseases, belong to bacterium infection, is the predecessor of anal fistula.This disease and anal fistula are that anal intestine three is big
One of disease, disease incidence are about 2%, account for the 8%~25% of anorectal disease.It is more common in 20~40 years old male, male's disease incidence
It is 3~4 times of women, children's disease incidence is also relatively high.Anal fissure be alimentary canal outlet from dentate line to anus edge this section is most narrow
Anal canal tissue surface is split, and aphtha is formed, and direction is parallel with the anal canal longitudinal axis, is in shuttle shape or ellipse, is about 0.5~1.0cm,
Often cause crissum severe pain.The most common position of anal fissure is the front and back center of anus, and center was more in the past.
The disease incidence of anal fissure accounts for about the 20% of anal intestine disease, and mostly based on young man, but anal fissure more favors women, especially year
Light women.China's women disease incidence is approximately 1.8 times of male, Japanese large intestine anus can will report the result is that 1.6 times.Anal fissure has
Acute and chronic point, chronic anal is since the course of disease is long and recurrent exerbation, the anal valve and anal papilla oedema of breach upper end cause
Hypertrophy of anal papilla, lower end skin take the shape of a bag to hang down and protrude downward from outside anus, formed " sentinel pile ", anal fissure, sentinel pile, anal papilla fertilizer
It often exists simultaneously greatly, referred to as anal fissure three is levied.
Currently on the market some hemorrhoid plaster for these illnesss therapeutic effect, it is mostly relatively slow ineffective, and not
Can effectively eradicate, be easy to appear relapse indications repeatedly always, to patient cause greatly pain with it is constant.
Summary of the invention
In view of the deficiencies of the prior art, the present invention provides a kind of preparation method of plaster for anal intestine treatment, it is right
In hemorrhoid, perianal abscess and anal fissure good effect, quick, short treating period can thoroughly solve patient's slight illness, and effect is very aobvious
It writes.
To reach above-mentioned purpose present invention provide the technical scheme that a kind of plaster preparation side for anal intestine treatment
Method comprising following steps: step 1: preparing composite material, and material includes 1-3 parts of aureomycin hydrochloride, and 1-3 parts of albolene,
1-2 parts of paraffin oil, 2-5 parts of metronidazole, 1-2 parts of borneol powder;Step 2: by 2 parts of albolene, 1 part of paraffin oil, it is added 10%
Pure water be stirred to form lotion, and be heated to 100 DEG C, be then shut off heating device, maintain 2 minutes;Step 3: to step
Lotion in rapid two is completely cooling, adds 2 parts of aureomycin hydrochloride, 3 parts of metronidazole and 1 part of borneol powder, abundant with lotion
30min is stirred evenly and stood, is then dispensed, acne cream finished product is obtained.
Further, step 2 during heating, needs constantly to be stirred lotion, until lotion is cooled to 40 DEG C
To 50 DEG C.
Compared with prior art, it has the advantages that
The present invention can thoroughly solve patient for hemorrhoid, perianal abscess and anal fissure good effect, quick, short treating period
Slight illness, effect highly significant.
Specific embodiment
A kind of preparation method of plaster for anal intestine treatment comprising following steps: step 1: prepare composite material, material
Material includes aureomycin hydrochloride 1-3 parts, 1-3 parts of albolene, 1-2 parts of paraffin oil, 2-5 parts of metronidazole, 1-2 parts of borneol powder;Step
Rapid two: by 2 parts of albolene, 1 part of paraffin oil, 10% pure water is added and is stirred to form lotion, and is heated to 100 DEG C,
It is then shut off heating device, maintains 2 minutes, during heating, needs constantly to be stirred lotion, until lotion is cooled to
40 DEG C to 50 DEG C, step 3: it is completely cooling to the lotion in step 2, add 2 parts of aureomycin hydrochloride, 3 parts of metronidazole and
, 30min is stirred and stood with lotion, is then dispensed, obtain acne cream finished product, wherein stone by 1 part of borneol powder
Wax oil and albolene have good moisturizing lubricating action, and borneol powder can play the role of cleaning heat dissipation, when smearing
More comfortable, this acne cream is exterior-applied article, smears 2-3 times within one day, plaster is applied to affected part, for hemorrhoid, perianal abscess with
And anal fissure can stop blooding in time, the healing of scattered stasis detumescence, myogenic, short treating period is quick, can thoroughly solve patient's slight illness, and effect is non-
Chang Xianzhu.
Finally, it should be noted that the above examples are only used to illustrate the technical scheme of the present invention and are not limiting, although reference
Preferred embodiment describes the invention in detail, those skilled in the art should understand that, it can be to of the invention
Technical solution is modified or replaced equivalently, and without departing from the spirit and scope of the technical solution of the present invention, should all be covered
In scope of the presently claimed invention.
Claims (2)
1. a kind of preparation method of plaster for anal intestine treatment, characterized by the following steps:
Step 1: preparing composite material, and material includes 1-3 parts of aureomycin hydrochloride, and 1-3 parts of albolene, 1-2 parts of paraffin oil, first
2-5 parts of nitre azoles, 1-2 parts of borneol powder;
Step 2: by 2 parts of albolene, 1 part of paraffin oil, 10% pure water is added and is stirred to form lotion, and is heated to
100 DEG C, it is then shut off heating device, is maintained 2 minutes;
Step 3: it is completely cooling to the lotion in step 2, add 2 parts of aureomycin hydrochloride, 3 parts of metronidazole and borneol powder
, 30min is stirred and stood with lotion, is then dispensed, obtain acne cream finished product by 1 part.
2. the preparation method of plaster according to claim 1 for anal intestine treatment, it is characterised in that: step 2 is heated
Cheng Zhong needs constantly to be stirred lotion, until lotion is cooled to 40 DEG C to 50 DEG C.
Priority Applications (1)
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CN201811088601.7A CN108969528A (en) | 2018-09-18 | 2018-09-18 | Preparing method of plaster for anal intestine treatment |
Applications Claiming Priority (1)
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CN201811088601.7A CN108969528A (en) | 2018-09-18 | 2018-09-18 | Preparing method of plaster for anal intestine treatment |
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CN108969528A true CN108969528A (en) | 2018-12-11 |
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CN201811088601.7A Pending CN108969528A (en) | 2018-09-18 | 2018-09-18 | Preparing method of plaster for anal intestine treatment |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111714443A (en) * | 2019-03-19 | 2020-09-29 | 王向军 | Anal canal lubricant and preparation method thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104666362A (en) * | 2013-12-02 | 2015-06-03 | 于玲玲 | Composite callus ointment |
CN106075064A (en) * | 2016-06-14 | 2016-11-09 | 高建新 | External granulation promoting putrefaction removing cream |
-
2018
- 2018-09-18 CN CN201811088601.7A patent/CN108969528A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104666362A (en) * | 2013-12-02 | 2015-06-03 | 于玲玲 | Composite callus ointment |
CN106075064A (en) * | 2016-06-14 | 2016-11-09 | 高建新 | External granulation promoting putrefaction removing cream |
Non-Patent Citations (1)
Title |
---|
汪波等: "甲硝唑-金霉素复合剂体外药效学的研究", 《现代应用药学》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111714443A (en) * | 2019-03-19 | 2020-09-29 | 王向军 | Anal canal lubricant and preparation method thereof |
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Application publication date: 20181211 |