CN108969528A - Preparing method of plaster for anal intestine treatment - Google Patents

Preparing method of plaster for anal intestine treatment Download PDF

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Publication number
CN108969528A
CN108969528A CN201811088601.7A CN201811088601A CN108969528A CN 108969528 A CN108969528 A CN 108969528A CN 201811088601 A CN201811088601 A CN 201811088601A CN 108969528 A CN108969528 A CN 108969528A
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CN
China
Prior art keywords
parts
lotion
stirred
anal
plaster
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811088601.7A
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Chinese (zh)
Inventor
肖君岩
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Quanzhou Asahi Business Co Ltd
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Quanzhou Asahi Business Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quanzhou Asahi Business Co Ltd filed Critical Quanzhou Asahi Business Co Ltd
Priority to CN201811088601.7A priority Critical patent/CN108969528A/en
Publication of CN108969528A publication Critical patent/CN108969528A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention proposes a kind of preparation method of plaster for anal intestine treatment, includes the following steps: step 1: preparing composite material, material includes 1-3 parts of aureomycin hydrochloride, 1-3 parts of albolene, 1-2 parts of paraffin oil, 2-5 parts of metronidazole, 1-2 parts of borneol powder;Step 2: by 2 parts of albolene, 1 part of paraffin oil, 10% pure water is added and is stirred to form lotion, and is heated to 100 DEG C, is then shut off heating device, maintains 2 minutes;Step 3: completely cooling to the lotion in step 2, add 2 parts of aureomycin hydrochloride, 3 parts of metronidazole and 1 part of borneol powder, it is stirred with lotion and stands 30min, then it is dispensed, obtains acne cream finished product, the present invention is for hemorrhoid, perianal abscess and anal fissure good effect, it is quick, short treating period can thoroughly solve patient's slight illness, effect highly significant.

Description

Preparing method of plaster for anal intestine treatment
Technical field
The present invention relates to acne cream, in particular to a kind of preparation method of plaster for anal intestine treatment.
Background technique
Hemorrhoid (being commonly called as hemorrhoid) are a kind of common diseases positioned at anus area, and any age can all fall ill, but with the age Increase, disease incidence gradually increases.In China, hemorrhoid are the most common anorectal diseases.
Perianal abscess, also known as perianorecrtal abscess, Chinese medicine are known as anus carbuncle.Perianal abscess is to betide anus, anal canal With periproctic acute suppuration infectious diseases, belong to bacterium infection, is the predecessor of anal fistula.This disease and anal fistula are that anal intestine three is big One of disease, disease incidence are about 2%, account for the 8%~25% of anorectal disease.It is more common in 20~40 years old male, male's disease incidence It is 3~4 times of women, children's disease incidence is also relatively high.Anal fissure be alimentary canal outlet from dentate line to anus edge this section is most narrow Anal canal tissue surface is split, and aphtha is formed, and direction is parallel with the anal canal longitudinal axis, is in shuttle shape or ellipse, is about 0.5~1.0cm, Often cause crissum severe pain.The most common position of anal fissure is the front and back center of anus, and center was more in the past.
The disease incidence of anal fissure accounts for about the 20% of anal intestine disease, and mostly based on young man, but anal fissure more favors women, especially year Light women.China's women disease incidence is approximately 1.8 times of male, Japanese large intestine anus can will report the result is that 1.6 times.Anal fissure has Acute and chronic point, chronic anal is since the course of disease is long and recurrent exerbation, the anal valve and anal papilla oedema of breach upper end cause Hypertrophy of anal papilla, lower end skin take the shape of a bag to hang down and protrude downward from outside anus, formed " sentinel pile ", anal fissure, sentinel pile, anal papilla fertilizer It often exists simultaneously greatly, referred to as anal fissure three is levied.
Currently on the market some hemorrhoid plaster for these illnesss therapeutic effect, it is mostly relatively slow ineffective, and not Can effectively eradicate, be easy to appear relapse indications repeatedly always, to patient cause greatly pain with it is constant.
Summary of the invention
In view of the deficiencies of the prior art, the present invention provides a kind of preparation method of plaster for anal intestine treatment, it is right In hemorrhoid, perianal abscess and anal fissure good effect, quick, short treating period can thoroughly solve patient's slight illness, and effect is very aobvious It writes.
To reach above-mentioned purpose present invention provide the technical scheme that a kind of plaster preparation side for anal intestine treatment Method comprising following steps: step 1: preparing composite material, and material includes 1-3 parts of aureomycin hydrochloride, and 1-3 parts of albolene, 1-2 parts of paraffin oil, 2-5 parts of metronidazole, 1-2 parts of borneol powder;Step 2: by 2 parts of albolene, 1 part of paraffin oil, it is added 10% Pure water be stirred to form lotion, and be heated to 100 DEG C, be then shut off heating device, maintain 2 minutes;Step 3: to step Lotion in rapid two is completely cooling, adds 2 parts of aureomycin hydrochloride, 3 parts of metronidazole and 1 part of borneol powder, abundant with lotion 30min is stirred evenly and stood, is then dispensed, acne cream finished product is obtained.
Further, step 2 during heating, needs constantly to be stirred lotion, until lotion is cooled to 40 DEG C To 50 DEG C.
Compared with prior art, it has the advantages that
The present invention can thoroughly solve patient for hemorrhoid, perianal abscess and anal fissure good effect, quick, short treating period Slight illness, effect highly significant.
Specific embodiment
A kind of preparation method of plaster for anal intestine treatment comprising following steps: step 1: prepare composite material, material Material includes aureomycin hydrochloride 1-3 parts, 1-3 parts of albolene, 1-2 parts of paraffin oil, 2-5 parts of metronidazole, 1-2 parts of borneol powder;Step Rapid two: by 2 parts of albolene, 1 part of paraffin oil, 10% pure water is added and is stirred to form lotion, and is heated to 100 DEG C, It is then shut off heating device, maintains 2 minutes, during heating, needs constantly to be stirred lotion, until lotion is cooled to 40 DEG C to 50 DEG C, step 3: it is completely cooling to the lotion in step 2, add 2 parts of aureomycin hydrochloride, 3 parts of metronidazole and , 30min is stirred and stood with lotion, is then dispensed, obtain acne cream finished product, wherein stone by 1 part of borneol powder Wax oil and albolene have good moisturizing lubricating action, and borneol powder can play the role of cleaning heat dissipation, when smearing More comfortable, this acne cream is exterior-applied article, smears 2-3 times within one day, plaster is applied to affected part, for hemorrhoid, perianal abscess with And anal fissure can stop blooding in time, the healing of scattered stasis detumescence, myogenic, short treating period is quick, can thoroughly solve patient's slight illness, and effect is non- Chang Xianzhu.
Finally, it should be noted that the above examples are only used to illustrate the technical scheme of the present invention and are not limiting, although reference Preferred embodiment describes the invention in detail, those skilled in the art should understand that, it can be to of the invention Technical solution is modified or replaced equivalently, and without departing from the spirit and scope of the technical solution of the present invention, should all be covered In scope of the presently claimed invention.

Claims (2)

1. a kind of preparation method of plaster for anal intestine treatment, characterized by the following steps:
Step 1: preparing composite material, and material includes 1-3 parts of aureomycin hydrochloride, and 1-3 parts of albolene, 1-2 parts of paraffin oil, first 2-5 parts of nitre azoles, 1-2 parts of borneol powder;
Step 2: by 2 parts of albolene, 1 part of paraffin oil, 10% pure water is added and is stirred to form lotion, and is heated to 100 DEG C, it is then shut off heating device, is maintained 2 minutes;
Step 3: it is completely cooling to the lotion in step 2, add 2 parts of aureomycin hydrochloride, 3 parts of metronidazole and borneol powder , 30min is stirred and stood with lotion, is then dispensed, obtain acne cream finished product by 1 part.
2. the preparation method of plaster according to claim 1 for anal intestine treatment, it is characterised in that: step 2 is heated Cheng Zhong needs constantly to be stirred lotion, until lotion is cooled to 40 DEG C to 50 DEG C.
CN201811088601.7A 2018-09-18 2018-09-18 Preparing method of plaster for anal intestine treatment Pending CN108969528A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811088601.7A CN108969528A (en) 2018-09-18 2018-09-18 Preparing method of plaster for anal intestine treatment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811088601.7A CN108969528A (en) 2018-09-18 2018-09-18 Preparing method of plaster for anal intestine treatment

Publications (1)

Publication Number Publication Date
CN108969528A true CN108969528A (en) 2018-12-11

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811088601.7A Pending CN108969528A (en) 2018-09-18 2018-09-18 Preparing method of plaster for anal intestine treatment

Country Status (1)

Country Link
CN (1) CN108969528A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111714443A (en) * 2019-03-19 2020-09-29 王向军 Anal canal lubricant and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104666362A (en) * 2013-12-02 2015-06-03 于玲玲 Composite callus ointment
CN106075064A (en) * 2016-06-14 2016-11-09 高建新 External granulation promoting putrefaction removing cream

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104666362A (en) * 2013-12-02 2015-06-03 于玲玲 Composite callus ointment
CN106075064A (en) * 2016-06-14 2016-11-09 高建新 External granulation promoting putrefaction removing cream

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
汪波等: "甲硝唑-金霉素复合剂体外药效学的研究", 《现代应用药学》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111714443A (en) * 2019-03-19 2020-09-29 王向军 Anal canal lubricant and preparation method thereof

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Application publication date: 20181211