CN102846789B - External application agent for treating alopecia - Google Patents
External application agent for treating alopecia Download PDFInfo
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- CN102846789B CN102846789B CN201210325227.4A CN201210325227A CN102846789B CN 102846789 B CN102846789 B CN 102846789B CN 201210325227 A CN201210325227 A CN 201210325227A CN 102846789 B CN102846789 B CN 102846789B
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Abstract
The present invention discloses an external application agent for treating alopecia. The external application agent is prepared from the following raw material drugs, by weight, 8-15 parts of tuber fleeceflower root, 7-12 parts of lobed kudzuvine root, 6-10 parts of wrinkled gianthyssop herb, 6-10 parts of tuckahoe, 10-15 parts of sweet wormwood herb, 10-15 parts of puncture weed, 6-10 parts of incised notopterygium rhizome and root, 6-10 parts of Chinese honeylocust fruit, 5-8 parts of fineleaf schizonepeta herb, 6-10 parts of divaricate saposhnikovia, 5-9 parts of eclipta prostrata, 3-7 parts of densefruit pittany root-bark, 3-8 parts of safflower, and 5-10 parts of angelica archang lica. The preparation process comprises the following steps: a, preparing all the raw material drugs into drug powder with a particle size of 40 meshes, and uniformly stirring; and b, uniformly mixing the drug powder and an alcohol with an alcoholicity of 80 DEG according to a weight ratio of 1:4-6, and soaking for 10-30 days. The external application agent of the present invention has effects of scurf removing, itching alleviating, grease removing, odor removing, hair growth, and alopecia treating, and provides a significant alopecia treatment effect, wherein the total effective rate is 93.30%.
Description
Technical field
The invention belongs to Chinese drug preparation technique field, be specially a kind of external preparation of hair growth.
Background technology
Alopecia, the traditional Chinese medical science is referred to as " alopecia areata ", " alopecia seborrheica ".Alopecia is a commonly encountered diseases, has alopecia areata, male pattern alopecia, seborrheic alopecia.Alopecia areata is the alopecia of limitation speckle shape, its feature is that lesion scalp is normal, NIP, no conscious sympton, Chang Yu stumbles on, head has circle or oval alopecia spot, the hair of alopecia area edge is more loose, is drawn out easily very much, and the sustainable several months of the course of disease of alopecia areata is to the several years, large multipotency spontaneous recovery, but also have outbreak repeatedly.In alopecia areata, approximately have case hair within a couple of days or several months of 5～10 % all to take off light and become alopecia totalis, minority severe patient can involve eyebrow, beard, and armpit hair, pubes etc., all de-light claims alopecia universalis; Male pattern alopecia is apt to occur in male person between twenty and fifty, and is more common in brain worker, the dry gloss that lacks of hair; Seborrheic alopecia, is also more common in male adults, and scalp is often greasy shinny or have a large amount of dandruffs, be canescence pityrosporum shape, conscious scratching where it itches, time permanent forehead both sides and head hair start symmetry and come off, sparse attenuating, affected part, due to hair follicle atrophy, usually causes permanent alopecia.The cause of disease of primary disease is not yet completely clear, and majority is thought and endocrine disturbance at present, and androgen increases, direct stimulation, and vascular function disorder, immunologic dysfunction and inherited genetic factors etc. are relevant.
Summary of the invention
The object of this invention is to provide a kind of external preparation of hair growth.
The external preparation of hair growth of the present invention, the crude drug by following parts by weight: 5～10 parts of 8～15 parts of Radix Polygoni Multiflori, 7～12 parts of Radix Puerariaes, 6～10 parts of Herba Pogostemoniss, 6～10 parts, Poria, 10～15 parts of Herba Artemisiae Annuaes, 10～15 parts of Fructus Tribulis, 6～10 parts of Rhizoma Et Radix Notopterygiis, 6～10 parts of Fructus Gleditsia, 5～8 parts of Herba Schizonepetae, 6～10 parts of Radix Saposhnikoviaes, 5～9 parts of Herba Ecliptaes, 3～7 parts of Cortex Dictamni, 3～8 parts, Flos Carthami, the Radix Angelicae Dahuricae are made.
Preferably, the external preparation of hair growth of the present invention can be by the crude drug of following parts by weight: 7 parts of 12 parts of Radix Polygoni Multiflori, 10 parts of Radix Puerariaes, 8 parts of Herba Pogostemoniss, 8 parts, Poria, 13 parts of Herba Artemisiae Annuaes, 13 parts of Fructus Tribulis, 8 parts of Rhizoma Et Radix Notopterygiis, 8 parts of Fructus Gleditsia, 6 parts of Herba Schizonepetae, 8 parts of Radix Saposhnikoviaes, 7 parts of Herba Ecliptaes, 5 parts of Cortex Dictamni, 5 parts, Flos Carthami, the Radix Angelicae Dahuricae are made.
The preparation process of external preparation of the present invention comprises the following steps: a, described parts by weight medicine is made to 40 object medicated powder stir; B, by medicated powder, 80 degree ethanol ratio 1:4～6 mix homogeneously by weight, soak 10～30 days.
When use every day with 2～3 spraying alopecias place, each 2～3 times (dry then spray again), the evening of every 2～3 days with Warm Wash for the first time, after 30～60 minutes scalp temperature are normal, spray again liquid medicine.
In this external preparation prescription, Radix Polygoni Multiflori nourishing the blood and yin, loosening bowel to relieve constipation, preventing the attack (or recurrence) of malaria, dispels the wind, and removing toxic substances, cures mainly blood deficiency Light-headedness, cardiopalmus, insomnia, the soreness of the waist and knees of the hepatic and renal YIN deficiency, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine constipation; Radix Puerariae induces sweat and brings down a fever, promote the production of body fluid, rash, yang invigorating antidiarrheal, for fever caused by exogenous pathogens headache, hypertension neck pain, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, have loose bowels; Agastachel patchoule summer heat dispelling induces sweat, removing dampness to restore normal function of the stomach, and for summertime flu, cold and heat headache, breast gastral cavity painful abdominal mass is vexed, and vomiting is had loose bowels, vomiting during pregnancy, nasal sinusitis, hands, tinea pedis; Poria has eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, and effect of mind tranquilizing and the heart calming, can control dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, malignant histocytosis, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade; The clear deficiency-heat thoroughly of Herba Artemisiae Annuae, removing heat from blood is except steaming, and except steaming, preventing the attack (or recurrence) of malaria, for pathogenic summer-heat heating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, malaria cold and heat, jaundice due to damp-heat; The Fructus Tribuli wind that falls apart, improving eyesight, the therapeutic method to keep the adverse QI flowing downwards, promoting the circulation of blood, controls headache, itching over the body, the conjunctival congestion nebula that swells, fullness in the chest, cough with dyspnea, lump in the abdomen, breast is difficult, carbuncle; The Rhizoma Et Radix Notopterygii exterior cold of faling apart, wind-damp dispelling, sharp joint, the wind and cold that cures cold, has a headache lossless, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore; Fructus Gleditsia expelling phlegm for arresting cough, logical the closing of having one's ideas straightened out, parasite killing eliminating stagnation, cures mainly productive cough dyspnea with fullness of the chest, apoplexy locked mouth, accumulation and obstruction of sputum, coma in silence, epilepsy, sore throat, constipation and anuresis, carbuncle scabies; The Herba Schizonepetae loose wind that induces sweat, rash, the skin ulcer that disappears, hemostasis, for flu, measles is sent out not smooth thoroughly, has blood in stool, metrorrhagia, epistaxis; Radix Saposhnikoviae expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion is jerked surely, for diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus; Herba Ecliptae nourishing the liver and kidney, crow palpus teeth consolidating, cooling blood for hemostasis, for deficiency of the liver and kindey, vertigo and tinnitus, blurring of vision, soreness of the waist and knees, the luxated tooth that turns white, stranguria caused by overstrain foul leukorrhea, spitting of blood, spits blood, epistaxis, hematuria, dysentery, metrorrhagia, traumatic hemorrhage; Cortex Dictamni heat clearing and damp drying, dispelling wind for relieving itching, removing toxic substances, for the rubella due to wind heat noxious dampness, eczema, scabies, jaundice, damp-heat arthralgia; Flos Carthami promoting blood circulation to restore menstrual flow, scattered silt pain relieving, for amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache; Radix Angelicae Dahuricae wind-damp dispelling, the evacuation of pus of invigorating blood circulation, granulation promoting pain relieving, for headache, toothache, nasal sinusitis, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus.All medicine compatibilities, hair " life " is moistened in removing scurf and relieving itching, the fat taste removal that disappears, training, hair growth accelerating, hair growth effect is remarkable.
Relevant clinical data is as follows: totally 30 examples, the oldest 60 years old, minimum 30 years old, wherein patients with alopecia areata 7 examples, alopecia totalis 1 example, puerperal alopecia 3 examples, local alopecia 19 examples.
Diagnostic criteria: hair is sparse even bald; Though hair without obviously sparse, comes off obviously in the recent period, conscious hair is front obviously to be reduced; There is no in the recent period the other diseases relevant to alopecia; Hair bits increase; Hair is shinny, and scalp oils and fats is obvious; Scalp itch.
Therapeutic Method: every day is with 2～3 spraying alopecias place, each 2～3 times (dry then spray again), the evening of every 2～3 days with Warm Wash for the first time, after 30～60 minutes scalp temperature are normal, spray again liquid medicine.
Criterion of therapeutical effect: recovery from illness: alopecia district all covers with hair, but sparse compared with other normal position, affected part squama, incrustation are disappeared, and pruritus disappears; Effective: alopecia district covers with hair substantially, but sparse compared with other normal positions, affected part squama, incrustation are disappeared, and pruritus alleviates; Effective: there is new growth in alopecia district, affected part squama, incrustation reduce, and pruritus takes a turn for the better; Invalid: alopecia district is without new growth, squama, incrustation, pruritus are unchanged, or treatment time is short and firmly do not carry out by doctor's advice, and hair is not any change.
After treatment, curative effect statistical result is as follows:
| Group | Number of cases | Recovery from illness (n%) | Effective (n%) | Effectively (n%) | Invalid (n%) | Total effective rate (n%) |
| Treatment group | 30 | 10（33.3%） | 12（40%） | 6（20%） | 2（6.67%） | 93.30% |
The specific embodiment
The invention will be further described for embodiment plan given below; but can not be interpreted as it is limiting the scope of the invention; according to the present invention, content, to nonessential improvement and adjustment more of the present invention, still belongs to protection scope of the present invention to those skilled in the art.
Embodiment 1: choose 120 grams of Radix Polygoni Multiflori, 100 grams of Radix Puerariaes, 80 grams of Herba Pogostemoniss, 80 grams, Poria, 130 grams of Herba Artemisiae Annuaes, 130 grams of Fructus Tribulis, 80 grams of Rhizoma Et Radix Notopterygiis, 80 grams of Fructus Gleditsia, 60 grams of Herba Schizonepetae, 80 grams of Radix Saposhnikoviaes, 70 grams of Herba Ecliptaes, 50 grams of Cortex Dictamni, 50 grams, Flos Carthami, 70 grams of the Radixs Angelicae Dahuricae, above-mentioned parts by weight medicine is made to 40 object medicated powder and stir; By medicated powder, 80 degree ethanol ratio 1:4 mix homogeneously by weight, soak 15 days.Every day is with 2～3 spraying alopecias place, each 2～3 times (dry then spray again), the evening of every 2～3 days with Warm Wash for the first time, after 30～60 minutes scalp temperature are normal, spray again liquid medicine.
Embodiment 2: select 80 grams of Radix Polygoni Multiflori, 70 grams of Radix Puerariaes, 60 grams of Herba Pogostemoniss, 60 grams, Poria, 100 grams of Herba Artemisiae Annuaes, 100 grams of Fructus Tribulis, 60 grams of Rhizoma Et Radix Notopterygiis, 60 grams of Fructus Gleditsia, 50 grams of Herba Schizonepetae, 60 grams of Radix Saposhnikoviaes, 50 grams of Herba Ecliptaes, 30 grams of Cortex Dictamni, 30 grams, Flos Carthami, 50 grams of the Radixs Angelicae Dahuricae, above-mentioned parts by weight medicine is made to 40 object medicated powder and stir; By medicated powder, 80 degree ethanol ratio 1:5 mix homogeneously by weight, soak 10 days.Every day is with 2～3 spraying alopecias place, each 2～3 times (dry then spray again), the evening of every 2～3 days with Warm Wash for the first time, after 30～60 minutes scalp temperature are normal, spray again liquid medicine.
Embodiment 3: select 150 grams of Radix Polygoni Multiflori, 120 grams of Radix Puerariaes, 100 grams of Herba Pogostemoniss, 100 grams, Poria, 150 grams of Herba Artemisiae Annuaes, 150 grams of Fructus Tribulis, 100 grams of Rhizoma Et Radix Notopterygiis, 100 grams of Fructus Gleditsia, 80 grams of Herba Schizonepetae, 100 grams of Radix Saposhnikoviaes, 90 grams of Herba Ecliptaes, 70 grams of Cortex Dictamni, 80 grams, Flos Carthami, 100 grams of the Radixs Angelicae Dahuricae, above-mentioned parts by weight medicine is made to 40 object medicated powder and stir; By medicated powder, 80 degree ethanol ratio 1:6 mix homogeneously by weight, soak 30 days.Every day is with 2～3 spraying alopecias place, each 2～3 times (dry then spray again), the evening of every 2～3 days with Warm Wash for the first time, after 30～60 minutes scalp temperature are normal, spray again liquid medicine.
Claims (3)
1. an external preparation for hair growth, it is characterized in that the crude drug by following parts by weight: 5～10 parts of 8～15 parts of Radix Polygoni Multiflori, 7～12 parts of Radix Puerariaes, 6～10 parts of Herba Pogostemoniss, 6～10 parts, Poria, 10～15 parts of Herba Artemisiae Annuaes, 10～15 parts of Fructus Tribulis, 6～10 parts of Rhizoma Et Radix Notopterygiis, 6～10 parts of Fructus Gleditsia, 5～8 parts of Herba Schizonepetae, 6～10 parts of Radix Saposhnikoviaes, 5～9 parts of Herba Ecliptaes, 3～7 parts of Cortex Dictamni, 3～8 parts, Flos Carthami, the Radix Angelicae Dahuricae are made.
2. external preparation according to claim 1, it is characterized in that the crude drug by following parts by weight: 7 parts of 12 parts of Radix Polygoni Multiflori, 10 parts of Radix Puerariaes, 8 parts of Herba Pogostemoniss, 8 parts, Poria, 13 parts of Herba Artemisiae Annuaes, 13 parts of Fructus Tribulis, 8 parts of Rhizoma Et Radix Notopterygiis, 8 parts of Fructus Gleditsia, 6 parts of Herba Schizonepetae, 8 parts of Radix Saposhnikoviaes, 7 parts of Herba Ecliptaes, 5 parts of Cortex Dictamni, 5 parts, Flos Carthami, the Radix Angelicae Dahuricae are made.
3. a method of preparing external preparation described in claim 1, is characterized in that comprising the following steps: a, described parts by weight medicine is made to 40 object medicated powder stir; B, by medicated powder, 80 degree ethanol ratio 1:4～6 mix homogeneously by weight, soak 10～30 days.
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| CN201210325227.4A CN102846789B (en) | 2012-09-06 | 2012-09-06 | External application agent for treating alopecia |
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| CN201210325227.4A CN102846789B (en) | 2012-09-06 | 2012-09-06 | External application agent for treating alopecia |
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| CN102846789A CN102846789A (en) | 2013-01-02 |
| CN102846789B true CN102846789B (en) | 2014-07-09 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103223158B (en) * | 2013-05-21 | 2014-08-06 | 辛舒畅 | External medicine for treating alopecia |
| CN104288638A (en) * | 2014-10-28 | 2015-01-21 | 合肥丰瑞隆生物科技有限公司 | Plaster for treating alopecia |
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| WO2006108319A1 (en) * | 2005-04-11 | 2006-10-19 | Yuehua Meng | Hair restorer |
| CN101450141B (en) * | 2008-12-30 | 2011-05-18 | 杜晓生 | Medicine for treating alopecia |
| CN101700396B (en) * | 2009-11-13 | 2011-12-07 | 黄远吉 | External medicine for curing alopecia and preparation method thereof |
| CN101716282B (en) * | 2009-12-23 | 2011-07-06 | 泰一和浦（北京）中医药研究院有限公司 | External Chinese medicinal composition with functions of hair loss prevention, hair strengthening and hair protection and preparation method thereof |
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