CN108967431A - A kind of Herbicidal combinations containing metamitron and haloxyfop-r-methyl - Google Patents

Abstract

The present invention relates to a kind of Herbicidal combinations and application thereof containing metamitron and haloxyfop-r-methyl.The Herbicidal combinations are made of two kinds of effective components of metamitron and haloxyfop-r-methyl and auxiliary agent, excipients, wherein the weight percent of the two is 1~80:80~1.The Herbicidal combinations can generate higher synergistic function, overcome and delay the development of weed resistance, and expand prevention spectrum, weeding speed is fast, and the lasting period is long, reduces drug cost, alleviates toxicity.The present invention can prevent and treat Sugarbeet Fields annual broadleaf weed and grassy weed effect is prominent, and effect is substantially better than single dose.

Description

A kind of Herbicidal combinations containing metamitron and haloxyfop-r-methyl

Technical field

The present invention relates to technical field of pesticide compounding, contain metamitron and haloxyfop-r-methyl more particularly to one kind Herbicidal combinations and application thereof.

Background technique

Beet is one of major economic crops, is also important sugar industry raw material.With the increase of beet cultivated area, Beet produces the economic benefit of direct relation peasant, the sustainable and stable development of sugar enterprise.How beet chemical herbicide is carried out Use and popularization is particularly important.Heilungkiang Sugarbeet Fields main weeds have: barnyard grass, wild avena sativa, herba setariae viridis, setaria glauca, Herba digitariae, dayflower, black nightshade, wolf tail grass, willow leaf thorn smartweed, Chenopodiaceae, Amaranthus retroflexus, piemarker, Siberian cocklebur, sowthistle, meadow pine, field thistle, reed Deng.Soil treatment and stem and leaf treatment after seedling two ways before seedling are mainly taken in the chemical weed control of Sugarbeet Fields.Should according to soil types, Situations such as topography, meteorological condition and weed community, selects chemical weed control mode appropriate.The advantages of soil treatment before seedling sowing is Management of weeds is in the budding period and before causing damages, and herbicidal effect is more stable, and dispenser cost is low.The disadvantage is that soil treatment It is affected by soil types, the content of organic matter, ph value.Soil is excessively viscous, and the content of organic matter is excessively high to be not easy using soil treatment. Drug effect climate condition influences greatly, and especially spring arid, wind are big and abnormal high temperature, low temperature can all influence herbicidal effect.Miao Hou The advantages of stalk leaf weedicide be influenced by soil types, the content of organic matter, soil moisture it is small, can according to be unearthed weeds type choosing Suitable herbicide is selected, it is with strong points.The disadvantage is that in drought, weeding under air humidity is small and the slow situation of weed growth It is ineffective.Medicament is also easy to produce phytotoxicity under the conditions of too high or too low for temperature.Herbicide after seedling must be unearthed in most of weeds And just can be carried out when there is the leaf area of certain adhering liquid medicine, so insecticide spraying time is relatively short, medication is timely, by outer Weather interference in boundary's is bigger.

Metamitron, which belongs in Triazinone selectivity, ceases translocated herbicide, mainly by bud scale and with absorbing, through wood Matter portion and bast are conducted to the young shoot of weeds and tender leaf, prevent weed growth point cell division from extending, it is dead to ultimately cause plant It dies.Soil is very strong to its adsorption capacity, and dose is largely adsorbed on upper soll layer after application, is avoided that plant strain growth point and the medicine The contact of agent makes it generate higher safety.It can be used for preventing and kill off Sugarbeet Fields gramineae weed and broadleaf weeds.

Haloxyfop-r-methyl belongs to selective herbicide after phenoxy carboxylic acid seedling, can be quickly by grass family after cauline leaf process The leaf of weeds absorbs, conduction to entire plant, inhibits the mitogenetic prevention of plant and kills weeds.

The present invention has made intensive studies the compounded formula screening of metamitron and haloxyfop-r-methyl, finds benzene piperazine Humulone and haloxyfop-r-methyl are compounded, and have significant synergistic function within the scope of certain compound proportion, and Single dose is compared, and medicament can be improved after compounding to the preventive effect of weeds, and the dosage widened degrass spectrum, reduce effective component, section About drug cost reduces environmental pollution and shortens pesticide residue.In actual use, metamitron and efficient haloxyfop-methyl Spirit is used in compounding to a variety of weeds on crop, as the annual broad-leaved of Sugarbeet Fields and gramineae weed have significant prevention and treatment effect Fruit completes the present invention after further study.

Summary of the invention

The present invention is intended to provide a kind of complex composition, and be made into small resistance risk, broad weed-killing spectrum, drug effect it is long, at The agriculture chemical compounding Herbicidal combinations that this is low, environmental pollution is small.

The technical solution of the present invention is as follows: agricultural double-crossed Herbicidal combinations, effective component is metamitron and efficient fluorine Pyrrole first standing grain spirit compounding.

The weight ratio of the effective component metamitron and haloxyfop-r-methyl is 1:80~80:1, preferably than being 1: 10~10:1.

Above-mentioned effective component metamitron and haloxyfop-r-methyl can be bought by commercial channel.

Herbicidal combinations of the invention can be prepared into the dosage form agriculturally allowed by the method for inhibition, including but unlimited In preferred dosage form: wettable powder, missible oil, water dispersible granules, suspending agent, microemulsion.

It further include agricultural system in addition to effective component metamitron and haloxyfop-r-methyl in above-mentioned Herbicidal combinations Agent auxiliary element.Effective component metamitron and haloxyfop-r-methyl total weight hundred shared in the Herbicidal combinations Dividing content is 1%~90%, preferably 20%~80%.

It includes carrier and auxiliary agent that the pesticidal preparations auxiliary, which becomes,.

The carrier is one of water, solvent or filler, two kinds or three kinds, the preferred deionized water of water.

The solvent is selected from n,N-Dimethylformamide, cyclohexanone, toluene, dimethylbenzene, dimethyl sulfoxide, methanol, second Alcohol, trimethylcyclohexanone, n-octylpyrrolidone, ethanol amine, triethanolamine, isopropylamine.N-Methyl pyrrolidone, propyl alcohol, One of butanol, ethylene glycol, diethylene glycol, ethylene glycol monomethyl ether, butyl ether, ethanol amine, isopropylamine, ethyl acetate or acetonitrile are more The mixture of kind composition.

The filler is in kaolin, diatomite, bentonite, attapulgite, white carbon black, starch or precipitated calcium carbonate The mixture of one or more compositions.

The auxiliary agent includes at least a kind of surfactant and can be also added antifreeze according to different use occasion and demand The other functions auxiliary agent such as agent, thickener, stabilizer, disintegrating agent, defoaming agent.

The surfactant is selected from one of emulsifier, dispersing agent, wetting agent or bleeding agent or four kinds.Above-mentioned surface Activating agent is the single dose or compound preparation of common nonionic surfactant or anionic surfactant.

Other function auxiliary agent one kind or five in antifreezing agent, thickener, stabilizer, disintegrating agent or defoaming agent Kind.

The emulsifier is selected from agriculture breast 500# (alkyl benzene calcium sulfonate), OP series phosphate (nonylphenol polyoxyethylene ether phosphorus Acid esters), 600# phosphate (phenyl phenol polyoxyethylene ether phosphate), styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether Disulfonic acid magnesium salts, triethanolamine salt, agriculture breast 400# (benzyl dimethyl phenol polyoxyethyl ether), Nongru-700 # (alkylphenol formaldehyde tree Rouge polyoxyethyl ether), peaceful cream 36# (phenethyl phenol formaldehyde resin polyoxyethyl ether), agriculture breast 1600# (phenethyl phenol polyoxyethanyl Polypropylene-base ether), ethylene oxide-propylene oxide block copolymer, OP serial (nonylphenol polyoxyethylene ether), the serial (castor-oil plant of BY Oily polyoxyethylene ether), agriculture breast 33# (alkylaryl polyoxyethylene poly-oxygen propylene aether), Span series (sorbitol anhydride monostearate), One of TWEEN Series (anhydrous sorbitol resin acid ester APEO) or AEO serial (fatty alcohol polyoxyethylene ether) are more The mixture of kind composition.

The dispersing agent be selected from polycarboxylate, lignosulfonates, APES formaldehyde condensation products sulfat, Alkyl benzene calcium sulfonate, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkyl phenol polyoxyethylene ether, aliphatic amine polyoxyethylene ether, fatty acid polyglycol The mixture of one of ethylene oxide ether or glycerol fatty acid ester polyoxyethylene ethe or a variety of compositions.

The wetting agent is selected from lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, soap The mixture of one of angle powder, silkworm excrement or spaonin powder or a variety of compositions.

The bleeding agent is selected from penetrating agent JFC (fatty alcohol polyoxyethylene ether), penetrant t (diisooctyl maleate Sulfonate), the mixture of one of azone or organosilicon or a variety of compositions.

The antifreezing agent is selected from the mixture of one of ethylene glycol, propylene glycol, glycerine or urea or a variety of compositions.

The thickener be selected from one of xanthan gum, polyvinyl alcohol, bentonite, carboxymethyl cellulose or aluminium-magnesium silicate or The mixture of a variety of compositions.

The stabilizer is selected from one kind or more of epoxidized soybean oil, epoxychloropropane, BHT, ethyl acetate, triphenyl phosphate The mixture of kind composition.

The disintegrating agent is selected from bentonite, urea, ammonium sulfate, aluminium chloride, low-substituted hydroxypropyl cellulose, lactose, lemon The mixture of one of acid, succinic acid or sodium bicarbonate or a variety of compositions.

The defoaming agent is selected from silicone oil, silicone compound, C10~C20 saturated fat acids compound or C8~C10 rouge The mixture of one of fat alcohol compound or a variety of compositions.

Above-mentioned substance can be commercially available.

The present invention has following advantages:

1, expand degrass spectrum, the broadleaf weeds common to Sugarbeet Fields and grass family etc. also have preferable control efficiency；

2, synergistic effect is obvious, is not the simple superposition of each component activity, and drug effect greatly improves；

3, prevention and treatment drug effect is prominent, and the lasting period is long, and resistance risk is small；

4, the field rate decline of effective component, reduces production and application cost, reduces pesticide residue and environmental pollution；

5, it is made of the effective component of different role mechanism, action site increases, and is conducive to overcome and delay the anti-medicine of weeds The generation of property.

Specific embodiment

The present invention is illustrated with reference to embodiments, but does not limit the invention to these specific embodiments.It is real It applies percentage in example to be weight percentage, the treatment dosage of field efficacy is effective ingredient consumption.

One, embodiment is prepared

1, wettable powder

Preparation method: in Example formulations ratio, carrier is added in effective component metamitron and haloxyfop-r-methyl In, and surfactant and other function auxiliary agent are added wherein, mixing remixes obtained wettable powder after air-flow crushing Agent.Capital equipment has mixing machine, airslide disintegrating mill.

Embodiment 1:(60% metamitron haloxyfop-r-methyl wettable powder) 1:2

Formula: metamitron, 20%；Haloxyfop-r-methyl, 40%；Wetting agent lauryl sodium sulfate, 2%；Dispersion Agent calcium lignosulfonate, 8%；Filler white carbon black, 18%, filler kaolin, surplus.

2, water dispersible granules

Preparation method: in Example formulations ratio, carrier is added in effective component metamitron and haloxyfop-r-methyl In, and surfactant and other function auxiliary agent are added wherein, mixing adds 10~25% water, so after air-flow crushing By kneading, granulation, drying, sieve obtained water dispersible granules product；Or the powder that crushed is sprayed water in boiling granulator, It is granulated, is dry, sieving product is made later.Capital equipment has mixing machine, airslide disintegrating mill, kneader, Squeezinggranulator, drying chamber Or fluidized bed drying or boiling granulator, screening machine.

Embodiment 2:(40% metamitron effective haloxyfop water dispersible granule) 1:3

Formula: metamitron, 10%；Haloxyfop-r-methyl, 30%；Dispersing agent Negel, 5%, dispersing agent Sodium lignin sulfonate, 7%；Wetting agent lauryl sodium sulfate, 2%；Urea (disintegrating agent) 5%, precipitated calcium carbonate are mended, surplus.

3, suspending agent

Preparation method: pressing formula rate, by effective component metamitron and haloxyfop-r-methyl, surfactant and its He is sequentially placed into reaction kettle functional aid, is mixed with water, and through high speed shear, wet process is sanded, and last homogeneous filtering is Obtain product.Capital equipment is batching kettle, colloid mill or homogeneous mixing machine, sand mill.

Embodiment 3:(35% metamitron and haloxyfop-r-methyl suspending agent) 2:5

Formula: metamitron, 10%；Haloxyfop-r-methyl, 25%；Wetting agent NP-10,1%；Dispersing agent polycarboxylic acids Salt, 4%；Thickener selects aluminium-magnesium silicate and xanthan gum, dosage are respectively 1.2% and 0.12%；Antifreezing agent selects propylene glycol, 5%；Organically-modified silicone antifoam agent, 0.2%；Water, surplus.

4, missible oil

Preparation method: carrier is added in effective component metamitron and haloxyfop-r-methyl in Example formulations ratio In, and surfactant and other function auxiliary agent are added wherein, it is uniformly mixed in being stirred kettle.Stirring Enamel reaction still, stainless steel stirred tank etc. can be selected in mixing kettle.

Embodiment 4:(30% metamitron high-efficiency flupirtine emulsifiable concentrate) 1:2

Formula: metamitron, 10%；Haloxyfop-r-methyl, 20%；Emulsifier selects agriculture breast 500# and agriculture breast OP- 10#, dosage are respectively 5% and 8%；Solvent selection cyclohexanone, 15%；Dimethylbenzene, surplus.

5, microemulsion

Preparation method: in Example formulations ratio, by effective component metamitron and haloxyfop-r-methyl solvent and Cosolvent is completely dissolved, and then adds other auxiliary agents, is uniformly mixed, is eventually adding water, after being sufficiently stirred, can be prepared by this hair Bright Herbicidal combinations microemulsion formulation.

Embodiment 5:(20% metamitron haloxyfop-r-methyl microemulsion) 1:4

Formula: metamitron, 4%；Haloxyfop-r-methyl, 16%；Solvent selects n,N-Dimethylformamide and hexamethylene Ketone, dosage are respectively 10% and 15%；Emulsifier selects agriculture breast 602# and agriculture breast 500#, and dosage is respectively 9% and 6%；Water, it is remaining Amount.

Two, BIOLOGICAL ACTIVITY EXAMPLES

BIOLOGICAL ACTIVITY EXAMPLES is divided into indoor biological activity Example and crop field BIOLOGICAL ACTIVITY EXAMPLES.

Active case 1: metamitron and haloxyfop-r-methyl mixture are to Sugarbeet Fields control of weeds recipe determination.

1 test method: according to NY/T1155.4-2006 " farm-chemical indoor determination test rule herbicide the 4th Point: active determination test cauline leaf spray-on process " it executes.

2 test targets: gramineae weed: herba digitariae, amur foxtail.Broadleaf weeds: Chenopodiaceae, thorn amaranth.

3 experimental designs: by pretreated for trying weed seed uniform broadcasting in soil surface, according to seed size earthing 05.cm~2.0cm is after planting transplanted to greenhouse routine culture.The laggard seedling singling in the ranks of weeds emergence, guarantees the density one of weeds It causes.

3 test medicines: metamitron raw medicine, haloxyfop-r-methyl raw medicine.

4 medicament configurations: it is accurate to claim certain mass metamitron raw medicine and haloxyfop-r-methyl raw medicine, it is dissolved with DMF, The clear water containing 0.1% Tween 80 emulsifier is added, stirs evenly, it is spare to be configured to certain concentration solution.

5 chemicals treatments: every processing is repeated 4 times, and is handled with not drug containing as control.Processing, which is placed in greenhouse, cultivates, periodically The growing state and survival condition for observing target weeds, range estimation in 14 days integrates activity of weeding after processing, and it is fresh to weigh aerial part Weight calculates fresh weight inhibition rate %, activity of weeding of the evaluation medicament to target weeds.

6 calculation methods:

6.1 ocular estimates: according to the extent of injury symptom and severity of test target weeds, the weeding for evaluating medicament is living Property.Herbicide ocular estimate evaluation criterion are as follows:

Rank	Standard
		1 grade	It is all dead
2 grades	It is equivalent to the 0~2.5% of blank district weeds
		3 grades	It is equivalent to the 2.6%~5% of blank district weeds
4 grades	It is equivalent to the 5.1%~10% of blank district weeds
		5 grades	It is equivalent to the 10.1%~15% of blank district weeds
6 grades	It is equivalent to the 15.1%~25% of blank district weeds
		7 grades	It is equivalent to the 25.1%~35% of blank district weeds
8 grades	It is equivalent to the 35.1%~67.5% of blank district weeds
		9 grades	It is equivalent to the 67.6%~100% of blank district weeds

6.2 numerical survey methods:

The insurance kind preventive effect or strain preventive effect of each processing are calculated according to each formula.

E=(C-T)/C × 100

In formula:

E: fresh weight preventive effect (or strain preventive effect)

C: control weeds aerial part fresh weight (or weeds strain number)

T: processing weeds aerial part fresh weight (or weeds strain number)

Active compound synergy Types Assessment method is as follows:

The evaluation of Gowing method, Gowing method are a kind of herbicide mixture synergy Types Assessment sides proposed nineteen sixty Method.It comprises the concrete steps that and first measures single dose and mixture to the preventive effect of target weeds, mixture is calculated by the actual measurement preventive effect of single dose Theoretical preventive effect, then it is evaluated into synergy type compared with the actual measurement preventive effect of mixture.

Mixture preparation theory preventive effect E0=X+Y (100-X)/100

In formula

E0 indicates the theoretical preventive effect of herbicide (A+B) when herbicide dosage is (P+Q).

X indicates the Weed-control effect of herbicide A when dosage is P；

Y indicates the Weed-control effect of herbicide B when dosage is Q；

By Gowing method, as E-E0 > 10%, illustrate that mixture herbicide generates synergistic effect；As E-E0 < -10%, say Bright mixture herbicide generates antagonism；When E-E0 value is between ± 10%, illustrate that mixture herbicide generates summation action, formula Middle E indicates the actual measurement preventive effect % of each processing.

7 statistical analysis

1 metamitron of table and synergy of the haloxyfop-r-methyl mixture to common broadleaf weeds and gramineae weed

According to experiments have shown that (being shown in Table 1): metamitron and haloxyfop-r-methyl mixture co-toxicity are apparently higher than single dose It uses.

Activity test 2: metamitron and haloxyfop-r-methyl mixture are to Sugarbeet Fields weed control field efficacy.

1 test basis: " pesticide field efficacy medicine test criterion (one) herbicide prevents and treats beet to GB/T17980.50-2000 Ground weeds ".

2 subjects: Sugarbeet Fields common weed barnyard grass, wild avena sativa, herba setariae viridis, setaria glauca, herba digitariae, dayflower, dragon Certain herbaceous plants with big flowers, wolf tail grass, willow leaf thorn smartweed, Chenopodiaceae, Amaranthus retroflexus, piemarker, Siberian cocklebur, sowthistle, meadow pine, field thistle, reed etc..

3 test medicines: metamitron mixture different from haloxyfop-r-methyl, 53% metamitron wettable powder, 108 grams/L high-efficiency flupirtine emulsifiable concentrate.

4 test process: beet broadcasts soil spraying treatment before rear seedling, 20 square metres of every plot area, and 4 repetitions separately set people Work weeding and blank control.

5 pilot surveies: 15 days investigation weeds death conditions after application record the remaining weeds strain number of each processing and measurement are miscellaneous Careless fresh weight calculates strain preventive effect and fresh weight preventive effect.

6 drug effect calculations:

In formula:

PT: treatment region careless quantity (or fresh weight) living

CK: blank area careless quantity (or fresh weight) living

7 conclusions

2 metamitron of table and haloxyfop-r-methyl are to Sugarbeet Fields weed control efficacy

3 metamitron of table and haloxyfop-r-methyl are to Sugarbeet Fields common weed preventive effect

According to experiments have shown that (table 2.3): 15d after application, of the invention 6 kinds mixed Herbicidal combinations are to beet field weed Preventive effect is excellent, and the total strain preventive effect of weeds and total fresh weight preventive effect prevent the strain of the weeds such as herba digitariae, dog tail, Chenopodiaceae, amaranth 95% or so Also about 90%, mixed composition is substantially better than single dose chloramines KIH 6127 and isopropyl methoxalamine, has for effect and fresh weight preventive effect Apparent synergistic effect.

Claims (9)

1. a kind of Herbicidal combinations and application thereof containing metamitron and haloxyfop-r-methyl, which is characterized in that its effectively at Being divided into metamitron and haloxyfop-r-methyl is primary activity ingredient, is subject to auxiliary agent and excipients compound.

2. Herbicidal combinations according to claim 1, which is characterized in that the effective component metamitron and efficient fluorine pyrrole The weight ratio of first standing grain spirit is 1:80~80:1.

3. Herbicidal combinations according to claim 2, which is characterized in that the effective component metamitron and efficient fluorine pyrrole The weight ratio of first standing grain spirit is preferably 1:10~10:1.

4. Herbicidal combinations described in any one of claim 1 to 3, which is characterized in that the effective component benzene piperazine grass Ketone and haloxyfop-r-methyl total weight percentage shared in the Herbicidal combinations are 1%~90%, remaining is Auxiliary ingredients for pesticide preparations.

5. Herbicidal combinations according to claim 4, which is characterized in that the effective component metamitron and efficient fluorine pyrrole First standing grain spirit total weight percentage shared in the Herbicidal combinations is preferably 20%~80%.

6. Herbicidal combinations according to claim 4, which is characterized in that the auxiliary ingredients for pesticide preparations include carrier and Auxiliary agent.

7. Herbicidal combinations according to claim 4, which is characterized in that its preferred dosage form is wettable powder, missible oil, water One kind of dispersible granule, suspending agent, microemulsion.

8. Herbicidal combinations according to claim 7, which is characterized in that its dosage form includes preferred dosage form but is not limited to above Dosage form.

9. a kind of Herbicidal combinations containing metamitron and haloxyfop-r-methyl according to claim 1 and application thereof exist Prevent and treat the application on Sugarbeet Fields annual grassy weeds.