CN1089163A - Cordyceps militaris oral liquid and preparation method thereof - Google Patents
Cordyceps militaris oral liquid and preparation method thereof Download PDFInfo
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- CN1089163A CN1089163A CN93119355A CN93119355A CN1089163A CN 1089163 A CN1089163 A CN 1089163A CN 93119355 A CN93119355 A CN 93119355A CN 93119355 A CN93119355 A CN 93119355A CN 1089163 A CN1089163 A CN 1089163A
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Abstract
A kind of cordyceps militaris oral liquid and preparation thereof comprise Cordyceps fermented product extract 5-15% in the compositions, Radix Panacis Quinquefolii 5-15%, Fructus Lycii 5-20%, extra large Carnis Margarita hydrolyzed solution 0-5%, sucrose 5-15%, water 20-80%.Can also comprise natural cordyceps, the Radix Astragali, Rhizoma Polygonati Odorati, Fructus Ligustri Lucidi, Radix Polygoni Multiflori.With the raw material decocting in water, filtering and concentrating, ethanol extraction, extracting solution be with sucrose, the dosing of extra large Carnis Margarita hydrolyzed solution, packing, sterilization, check finished product.Oral liquid nutritional labeling of the present invention is abundant, contains several amino acids, has the intelligence of increasing, body-building, skin care effect.
Description
The present invention relates to medical preparation health product, specifically is a kind of oral liquid and compound method thereof based on artificial Cordyceps.
Cordyceps is the distinctive precious Chinese medicinal herbs of China, has tonic effect preferably.Because of its growth is difficult for, the medicine source is in short supply, costs an arm and a leg, and supply falls short of demand.In order to overcome this imbalance between supply and demand, in recent years, the domestic employing with natural cs fungi fermentation method cultivated, and obtained artificial aweto bacterium (abbreviation artificial aweto).Zhang Tushan etc. studies show that: artificial aweto has similar chemical constituent to natural cs, pharmacological action, and clinical efficacy and toxicity are lower, and (pharmacy is circulated a notice of, 1981:16(3): 11).At present, the domestic artificial aweto that generally adopts is made various preparations, as " conscience grass ", " zhiling capsules ", " Quan Shuibao ", " mind calming treasured ", " Chinese caterpillar fungus extract ", " Cordyceps chicken essence " etc.CN1069658A discloses a kind of cordyceps sonensis oral liquid, be adopt with the generic Cordyceps militaris of Cordyceps be raw material, through seed culture, prepared such as extraction have effects such as anticancer, defying age, control cardiovascular disease.Disclosed Chinese caterpillar fungus preparation or compound preparation, or adopting natural cordyceps is raw material, the medicine source is in short supply; Or adopt single artificial aweto preparation, and composition is single, and the tonic effect is still undesirable.
The objective of the invention is to disclose a kind of Cordyceps extract with artificial fermentation cultivation gained is primary raw material, is equipped with the Chinese medicine that other has the health-care tonic function, goes out to have instant by certain prepared, and composition is complete, the oral liquid that tonic is effective.
The scheme that the object of the invention realizes, be in the oral liquid compositions of preparation, to comprise Cordyceps fermented product extract, Radix Panacis Quinquefolii, Fructus Lycii, extra large Carnis Margarita hydrolyzed solution, sucrose, can also comprise that one in natural cordyceps, the Radix Astragali, Rhizoma Polygonati Odorati, Fructus Ligustri Lucidi, the Radix Polygoni Multiflori is to several.The percentage composition of each component (weight) is in the compositions: Cordyceps fermented product extract 5-15%, Radix Panacis Quinquefolii 5-15%, Fructus Lycii 5-20%, extra large Carnis Margarita hydrolyzed solution 0-5%, sucrose 5-15%, water 20-80%.When also including other composition in the compositions, be to add as one feels fit, interpolation back shared percentage composition (weight) in compositions is: natural cordyceps 0-3%, Radix Astragali 0-15%, Rhizoma Polygonati Odorati 0-15%, Fructus Ligustri Lucidi 0-15%, Radix Polygoni Multiflori 0-15%.
Oral liquid compositions best composition of the present invention (weight) is: Cordyceps fermented product extract 8-12%, Radix Panacis Quinquefolii 6-10%, Fructus Lycii 10-20%, extra large Carnis Margarita hydrolyzed solution 1-3%, sucrose 5-12%, water 43-70%.
The producing of Cordyceps fermented product extract in the present composition is the natural cs fungus that will be separated to, and adopts known microbial culture method, cultivates through artificial fermentation and obtains mycelium, again through separating and cold drying gets the Chinese caterpillar fungus fermentation extract.Producing of sea Carnis Margarita hydrolyzed solution is that Carnis Margarita is twisted into minced meat, adds sulphuric acid an amount of (to pH value 1-5), aqueous solution heating hydrolysis 24-48 hour, and adding calcium hydroxide makes sulphuric acid generate calcium sulfate and removes by filter, and gets hydrolyzed solution.
The preparation of oral liquid of the present invention is to be undertaken by following processing step:
A, raw material decocting in water 2～3 hours, filter and remove residue;
B, get filtrate heating and concentrate;
C, ethanol extraction reclaim ethanol;
D, extracting solution be with sucrose, water, the dosing of extra large Carnis Margarita hydrolyzed solution, packing, sterilization, check finished product.
Oral liquid of the present invention is a rufous liquid, has the fragrance of Cordyceps, Radix Panacis Quinquefolii, and it is sweet to distinguish the flavor of, and meets food hygienic standard.Finished product soluble solid 〉=35.0, manna alcohols material 〉=0.7g/100ml, free amino acid 〉=700mg/100ml.
Oral liquid of the present invention is owing to added other composition on the basis of artificial aweto, nutritional labeling is abundant, contain several amino acids, vitamin, trace element, body health benefits compositions such as Cordyceps rhzomorph, manna alcohols material, adenosine, sterol, Saponin, polysaccharide have the function that increases intelligence, body-building, skin care.The product oral good absorbing, the maintenance phase can reach 18 months.
Embodiment 1:
Get 2.1 kilograms of cephalosporium sinensis fermented product extract, 1.2 kilograms of Radix Panacis Quinquefoliis, 4 kilograms of Fructus Lycii add 60 kilograms in water and boiled 3 hours, filter and remove residue is got the filtrate heating and is concentrated into 7 kilograms, add 12 kilograms of ethanol and leave standstill filtration in 3 days, behind the recovery ethanol, add 0.3 kilogram of 2.4 kilograms of white sugar and extra large Carnis Margarita hydrolyzed solution, add water to 20,000 milliliters, be distributed into per 10 milliliters 1 bottled, altogether 2000,0.7 kPa, 115 ℃ sterilizations 30 minutes.Chinese caterpillar fungus fermentation extract 10.5% in the gained finished product, Radix Panacis Quinquefolii 6%, Fructus Lycii 20%, extra large Carnis Margarita hydrolyzed solution 1.5%, sucrose 12%.Finished product detects through Guangxi Bureau of Technical Supervision condensed food quality monitoring testing station, soluble solid 36.07%, pH value 5.63, manna alcohols material 0.96g/100ml, free amino acid 805.0mg/100ml.
Embodiment 2:
Get 1.5 kilograms of Chinese caterpillar fungus fermentation extracts, 2 kilograms of Radix Panacis Quinquefoliis, 3 kilograms of Fructus Lyciis, 5 kilograms of the Radixs Astragali add 80 kilograms in water and boiled 3 hours, and filter and remove residue is got the filtrate heating and is concentrated into 11.5 kilograms, add 20 liters of ethanol, stir evenly, left standstill 3 days, filter, with 1 kilogram of sucrose, add 300 milliliters of extra large Carnis Margarita hydrolyzed solutions behind the recovery ethanol, add water to 20,000 milliliters, be distributed into per 10 milliliters 1 bottled, boiling sterilization 30 minutes finished product.Chinese caterpillar fungus fermentation extract 7.5% in the gained finished product, Radix Panacis Quinquefolii 10%, Fructus Lycii 15%, the Radix Astragali 25%, extra large Carnis Margarita hydrolyzed solution 1.5%, sucrose 5%.
Embodiment 3:
Get 1 kilogram of Chinese caterpillar fungus fermentation extract, 1 kilogram of Radix Panacis Quinquefolii, 1 kilogram of Fructus Lycii, 1 kilogram of the Radix Astragali, 0.2 kilogram of natural cordyceps, 1 kilogram of Rhizoma Polygonati Odorati, 1 kilogram of Fructus Ligustri Lucidi, 1 kilogram of Radix Polygoni Multiflori, adding 80 kilograms in water boiled 3 hours, filter and remove residue is got the filtrate heating and is concentrated into 7.2 kilograms, adds 20 kilograms of ethanol, stirs evenly, left standstill 3 days, filter, reclaim ethanol after, with 1 kilogram of 1.8 kilograms of sucrose and extra large Carnis Margarita hydrolyzed solution, add water to 20,000 milliliters, be distributed into per 10 milliliters 1 bottled, altogether 2000,0.7 kPa, 115 ℃ sterilizations 30 minutes finished product.Chinese caterpillar fungus fermentation extract 5% in the gained finished product, Radix Panacis Quinquefolii 5%, Fructus Lycii 5%, the Radix Astragali 5%, natural cordyceps 1%, Rhizoma Polygonati Odorati 5%, Fructus Ligustri Lucidi 5%, Radix Polygoni Multiflori 5%, extra large Carnis Margarita hydrolyzed solution 5%, sucrose 9%.
Embodiment 4:
Get 3 kilograms of Chinese caterpillar fungus fermentation extracts, 3 kilograms of Radix Panacis Quinquefoliis, 2 kilograms of Fructus Lyciis add 60 kilograms in water and boiled 3 hours, filter and remove residue is got the filtrate heating and is concentrated into 8 kilograms, add 12 kilograms of ethanol and leave standstill filtration in 3 days, reclaim ethanol after, with 0.6 kilogram of 1.4 kilograms of sucrose and extra large Carnis Margarita hydrolyzed solution, add water to 20,000 milliliters, be distributed into per 10 milliliters 1 bottled, altogether 2000,0.7 kPa, 115 ℃ sterilizations 30 minutes.Chinese caterpillar fungus fermentation extract 15% in the gained finished product, Radix Panacis Quinquefolii 15%, Fructus Lycii 10%, extra large Carnis Margarita hydrolyzed solution 3%, sucrose 7%.
Embodiment 5:
Get 1.6 kilograms of Chinese caterpillar fungus fermentation extracts, 1.2 kilograms of Radix Panacis Quinquefoliis, 2 kilograms of Fructus Lyciis, add 60 kilograms in water and boiled 2 hours, filter and remove residue is got the filtrate heating and is concentrated into 4.8 kilograms, adds 20 liters of ethanol, stir evenly, left standstill 3 days, and filtered, reclaim behind the ethanol with 1 kilogram of sucrose, add 200 milliliters of extra large Carnis Margarita hydrolyzed solutions, add water to 20,000 milliliters, be distributed into per 10 milliliters 1 bottled, boiling sterilization 30 minutes finished product.Chinese caterpillar fungus fermentation extract 8% in the gained finished product, Radix Panacis Quinquefolii 6%, Fructus Lycii 10%, extra large Carnis Margarita hydrolyzed solution 1%, sucrose 5%.
Embodiment 6:
Get 2.4 kilograms of Chinese caterpillar fungus fermentation extracts, 2 kilograms of Radix Panacis Quinquefoliis, 4 kilograms of Fructus Lyciis add 60 kilograms in water and boil 3 hours filter and remove residues and get the filtrate heating and be concentrated into 8.4 kilograms, add 20 liters of ethanol, stir evenly, and leave standstill 3 days, filter.Reclaim behind the ethanol with 2.4 kilograms of sucrose, add 0.6 kilogram of extra large Carnis Margarita hydrolyzed solution, add water to 20,000 milliliters, be distributed into per 10 milliliters 1 bottled, boiling sterilization 30 minutes finished product.Chinese caterpillar fungus fermentation extract 12% in the gained finished product, Radix Panacis Quinquefolii 10%, Fructus Lycii 20%, extra large Carnis Margarita hydrolyzed solution 3%, sucrose 12%.
Claims (5)
1, a kind of cordyceps militaris oral liquid comprises artificial Cordyceps fermented product extract, sucrose and water in the compositions, it is characterized in that also comprising Radix Panacis Quinquefolii, Fructus Lycii, extra large Carnis Margarita hydrolyzed solution.
2,, it is characterized in that the percentage composition (weight) of each component in the compositions is: Cordyceps fermented product extract 5-15%, Radix Panacis Quinquefolii 6-12% according to the described cordyceps militaris oral liquid of claim 1, Fructus Lycii 5-20%, sea Carnis Margarita hydrolyzed solution 0-5%, sucrose 5-15%, water 20-80%.
3, according to the described cordyceps militaris oral liquid of claim 1, it is characterized in that the compositions best composition is: Cordyceps fermented product extract 8-12%, Radix Panacis Quinquefolii 6-10%, Fructus Lycii 10-20%, extra large Carnis Margarita hydrolyzed solution 1-3%, sucrose 5-12%, water 43-70%.
4, according to the described cordyceps militaris oral liquid of claim 1, it is characterized in that also comprising in the compositions that one in natural cordyceps, the Radix Astragali, Rhizoma Polygonati Odorati, Fructus Ligustri Lucidi, the Radix Polygoni Multiflori is to several, adding back shared percentage composition (weight) in compositions is: natural cordyceps 0-3%, Radix Astragali 0-25%, Rhizoma Polygonati Odorati 0-15%, Fructus Ligustri Lucidi 0-15%, Radix Polygoni Multiflori 0-15%.
5,, it is characterized in that being undertaken by following processing step according to the preparation method of claim 1 or 4 described cordyceps militaris oral liquids:
A, raw material decocting in water 2-3 hour, filter and remove residue;
B, get filtrate heating and concentrate;
C, ethanol extraction reclaim ethanol;
D, extracting solution are with sucrose, the dosing of extra large Carnis Margarita hydrolyzed solution, and packing is sterilized, check.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93119355A CN1089163A (en) | 1993-10-27 | 1993-10-27 | Cordyceps militaris oral liquid and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93119355A CN1089163A (en) | 1993-10-27 | 1993-10-27 | Cordyceps militaris oral liquid and preparation method thereof |
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| CN1089163A true CN1089163A (en) | 1994-07-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN93119355A Pending CN1089163A (en) | 1993-10-27 | 1993-10-27 | Cordyceps militaris oral liquid and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103039993A (en) * | 2013-01-25 | 2013-04-17 | 湖南今珠生物科技有限公司 | Pearl and cordyceps healthcare preparation and production process thereof |
-
1993
- 1993-10-27 CN CN93119355A patent/CN1089163A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103039993A (en) * | 2013-01-25 | 2013-04-17 | 湖南今珠生物科技有限公司 | Pearl and cordyceps healthcare preparation and production process thereof |
| CN103039993B (en) * | 2013-01-25 | 2016-08-03 | 湖南今珠生物科技有限公司 | A kind of Margarita Chinese caterpillar fungus health preparation and production technology thereof |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
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| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |