CN1089155A

CN1089155A - " Tiansuijianguling " of treatment osteoporosis

Info

Publication number: CN1089155A
Application number: CN 93100734
Authority: CN
Inventors: 张金生
Original assignee: Individual
Current assignee: Individual
Priority date: 1993-01-01
Filing date: 1993-01-01
Publication date: 1994-07-13

Abstract

The Tiansuijianguling of treatment osteoporosis belongs to the clinical new drug of orthopaedics.The present invention is made up of Radix Dipsaci, Radix Rehmanniae Preparata, Rhizoma Dioscoreae, Fructus Corni, Carapax et Plastrum Testudinis, Rhizoma Drynariae, Cornu Cervi Pantotrichum, Fructus Mori, Rhizoma Polygonati, Rhizoma Chuanxiong, Radix Angelicae Sinensis ten Herba indigoferae Pseudotinctoriae, all medicines share have nourishing YIN for suppressing the hyperactive YANG, the function of invigorating the spleen and replenishing QI, the kidney invigorating and essence nourishing, Tiansuijianguling, and can reach the activity hormone, the activation vitamin D, the purpose of enhancing bone density.This medicine manufacture method is simple, taking convenience, and good effect has no side effect, and is applicable to the treatment of middle-aged and senile osteoporosis, also is applicable to the treatment of aseptic necrosis of femoral head and delayed union of fracture.

Description

" Tiansuijianguling " of treatment osteoporosis

The invention belongs to the clinical new drug of orthopaedics

To be that a kind of person in middle and old age are multiple drop to main worldwide disease with bone mineral content to osteoporosis, its pathogenic factor is owing to person in middle and old age's asthenia of renal qi, sex hormones secretion reduce, cause bone metabolism disturbance, osteoporosis appears, it can cause that not only lumbago and backache also very easily causes the fracture at each position of whole body, quickens people's aging.It is reported that human body beginning in 30 years old bone mineral content is lost with annual 1% speed, descend 30% to 60 years old bone ore deposit.

At present domestic and international also not good therapy is used for the treatment of primary disease.Though some hospitals adopt gonadotherapy treatment osteoporosis, act on because of this therapy has certain paying, and curative effect is not ideal enough, therefore can not be as the routine treatment prolonged application; Also have part hospital application calcium preparation therapy, but can not fundamentally treat osteoporosis.More hospital then feels simply helpless to the treatment of primary disease.

Task of the present invention provides a kind of ideal medicament of fundamentally treating osteoporosis.By medication treatment, the activity hormone, the activation vitamin D, thus bone density is increased, osteoporosis obtains medical treatment.Advantages such as this medical instrument has taking convenience, and therapeutic effect is good, and is without any side effects.

The prescription of this medicine is formed: Radix Dipsaci (5～20g), Radix Rehmanniae Preparata (5～30g), Rhizoma Dioscoreae (5～15g), Fructus Corni (5～15g), Carapax et Plastrum Testudinis (5～15g), Rhizoma Drynariae (5～20g), Cornu Cervi Pantotrichum (1～3g), Fructus Mori (5～20g), Rhizoma Polygonati (5～20g), Rhizoma Chuanxiong (5～15g), Radix Angelicae Sinensis (5～20g)

Pharmacological action further specifies to this prescription below.Radix Dipsaci: invigorating the liver and kidney, promoting the circulation of blood arteries and veins, reuniting the fractured tendons and bones; Radix Rehmanniae Preparata: nourishing the blood and yin, vital essence replenishing and marrow benifiting; Rhizoma Dioscoreae: supplementing QI and nourishing YIN, spleen reinforcing, lung, kidney; Fructus Corni: liver and kidney tonifying, the convergence astringent or styptic treatment for spontaneous sweating; Carapax et Plastrum Testudinis: nourishing YIN for suppressing the hyperactive YANG, replenishing kidney and strengthening bone, the reinforcing the heart of nourishing blood; Rhizoma Drynariae: mend bone, invigorate blood circulation, stop blooding, treat bone and wither; Cornu Cervi Pantotrichum: kidney-replenishing, benefiting essence-blood, bone and muscle strengthening; Fructus Mori: nourishing YIN and supplementing blood, promote the production of body fluid, intestine moistening; Rhizoma Polygonati: lung moistening, YIN nourishing, invigorating the spleen and replenishing QI, fill out bone marrow; Rhizoma Chuanxiong: blood-activating and qi-promoting, wind-expelling pain-stopping; Radix Angelicae Sinensis: enrich blood, invigorate blood circulation, pain relieving, intestine moistening." interior warp, the big opinion of YIN YANG classification of natural phenomena " cloud: " kidney producing bone marrow, marrow occupy in the bone, and bone relies in the supplementing nutrition of marrow, the kidney essense abundance, biochemical active, then skeleton is firm tough ".As deficiency of kidney-essence, skeleton biochemistry is passive, a little less than then skeleton withers, so saying of " people cross 40 kidney qis beginning decline " arranged, illustrate that later kidney qi of middle age loses gradually, and skeleton loses the nourishing of kidney essense, so be prone to osteoporosis.The all medicines of this invention share, and play the effect of nourishing YIN for suppressing the hyperactive YANG, invigorating the spleen and replenishing QI, the kidney invigorating and essence nourishing, Tiansuijianguling altogether.Prove according to modern medicine study: osteoporosis for suffer from a deficiency of the kidney, due to the kidney hypofunction.Kidney-reinforcing drug has the activity hormone; promote the protection gonad function; promptly protect HPT-adrenal gland-gonad axis function; promote the interior activation of body of vitamin D; participate in alcium and phosphor metabolization, vitamin D is effectively utilized, the absorbtivity of calcium increases; it is calcareous that the sclerotin that impels sparse flaccidity to contract obtains in a large number replenishing, thereby reach the purpose that strengthens bone density.

During making, at first all medicine crushed after being dried are become the powder face, break into tablet then or make electuary and all can.

During use, obey 5g at every turn, whenever take medicine and checked a bone density recovery situation in one month every day three times, bone density gets final product drug withdrawal after recovering normally.

Through clinical treatment 90 routine osteoporosis patients, total effective rate can reach more than 90% at present, and medicine time, average out to was about 4 months.

This medicine manufacture method is simple, taking convenience, and therapeutic effect is good, has no side effect, and is applicable to the treatment of middle-aged and senile osteoporosis, also is applicable to the treatment of aseptic necrosis of femoral head and delayed union of fracture.

The following examples are described further the present invention:

Get Radix Rehmanniae Preparata 30g, Radix Dipsaci 20g, Rhizoma Drynariae 20g, Fructus Mori 20g, Rhizoma Polygonati 20g, Radix Angelicae Sinensis 20g, Rhizoma Dioscoreae 15g, Fructus Corni 15g, Carapax et Plastrum Testudinis 15g, Rhizoma Chuanxiong 15g, Cornu Cervi Pantotrichum 3g, be ground into face after the oven dry, sieve then, fine flour is broken into tablet or electuary, took 5g, every day three times, month medicine of every take in 30 minutes after meal at every turn, survey one time bone density, get final product drug withdrawal after bone density is normal.

Claims

1, " Tiansuijianguling " of treatment osteoporosis is characterized in that prescription has Radix Dipsaci 5～20g (1), Radix Rehmanniae Preparata 5～30g (2), Rhizoma Drynariae 5～20g (3), Fructus Mori 5～20g (4) Rhizoma Polygonati 5～20g (5), Radix Angelicae Sinensis 5～20g (6), Rhizoma Dioscoreae 5～15g (7), Fructus Corni 5～15g (8), Carapax et Plastrum Testudinis 5～15g (9), Cornu Cervi Pantotrichum 1～3g (10), Rhizoma Chuanxiong 5～15g (11)