CN103055085B - Traditional Chinese medical preparation for treating iron-deficiency anemia - Google Patents
Traditional Chinese medical preparation for treating iron-deficiency anemia Download PDFInfo
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Abstract
本发明涉及一种治疗缺铁性贫血的中药制剂,其特征是:由如下重量份的原料药制成:黄芪18-22份、太子参8-10份、仙鹤草13-17份、熟地黄10-14份、当归13-17份、大枣18-22份、黑芝麻18-22份、何首乌13-17份、党参18-22份、阿胶10-14份、陈皮8-10份、香附8-10份、枸杞子6-8份、甘草6-8份。本发明具有标本兼治,疗效显著,副作用小的优点;经临床验证,本发明治疗缺铁性贫血有效率为97%。The invention relates to a traditional Chinese medicine preparation for treating iron deficiency anemia. 10-14 parts, 13-17 parts of angelica, 18-22 parts of jujube, 18-22 parts of black sesame, 13-17 parts of Polygonum multiflorum, 18-22 parts of Codonopsis pilosula, 10-14 parts of donkey-hide gelatin, 8-10 parts of tangerine peel, Attach 8-10 parts, 6-8 parts of medlar, 6-8 parts of licorice. The invention has the advantages of treating both symptoms and root causes, significant curative effect and less side effects; through clinical verification, the effective rate of the invention for treating iron-deficiency anemia is 97%.
Description
技术领域 technical field
本发明涉及中药制药技术领域,特别是涉及一种治疗缺铁性贫血的中药制剂。 The invention relates to the technical field of traditional Chinese medicine pharmacy, in particular to a traditional Chinese medicine preparation for treating iron deficiency anemia.
背景技术 Background technique
缺铁性贫血是指机体对铁的需求与供给失衡,导致体内贮存铁耗尽,继之红细胞内铁缺乏从而引起的贫血。缺铁性贫血是最常见的贫血;当铁量增加而铁摄入不足、铁吸收障碍、铁丢失过多均可引起缺铁性贫血;症状主要表现为乏力、易倦、头晕、头痛、眼花、耳鸣、心悸、气短、纳差等;缺铁性贫血是贫血中常见类型,普遍存在于世界各地;在生育年龄妇女和婴幼儿这种贫血的发病率很高。 Iron deficiency anemia refers to the imbalance between the body's demand and supply of iron, leading to the depletion of iron storage in the body, followed by anemia caused by iron deficiency in red blood cells. Iron deficiency anemia is the most common anemia; iron deficiency anemia can be caused by insufficient iron intake, iron absorption disorder, and excessive iron loss when the amount of iron increases; the main symptoms are fatigue, tiredness, dizziness, headache, and vertigo , tinnitus, palpitations, shortness of breath, anorexia, etc.; iron deficiency anemia is a common type of anemia, which is ubiquitous in all parts of the world; the incidence rate of this anemia is very high in women of reproductive age and infants.
目前,治疗缺铁性贫血主要是补铁,补铁药物有硫酸亚铁、右旋糖酐铁、葡萄糖酸亚铁、山梨醇铁、富马酸亚铁和多糖铁复合物等;这些药物只能补铁,但不能根除病因,并存在见效慢、副作用较大的不足。 At present, the main treatment for iron deficiency anemia is iron supplementation. Iron supplementation drugs include ferrous sulfate, iron dextran, ferrous gluconate, iron sorbitol, ferrous fumarate, and polysaccharide iron complexes; these drugs can only supplement iron , but the cause of disease cannot be eradicated, and there are shortcomings of slow effect and relatively large side effects.
发明内容 Contents of the invention
本发明要解决的技术问题是:为解决现有技术的不足,本发明提供了一种治疗缺铁性贫血的中药制剂,本发明具有标本兼治,疗效显著,副作用小的优点。 The technical problem to be solved by the present invention is: in order to solve the deficiencies of the prior art, the present invention provides a traditional Chinese medicine preparation for treating iron deficiency anemia.
一种治疗缺铁性贫血的中药制剂,其特征是:由如下重量份的原料药制成:黄芪18-22份、太子参8-10份、仙鹤草13-17份、熟地黄10-14份、当归13-17份、大枣18-22份、黑芝麻18-22份、何首乌13-17份、党参18-22份、阿胶10-14份、陈皮8-10份、香附8-10份、枸杞子6-8份、甘草6-8份。 A traditional Chinese medicine preparation for treating iron deficiency anemia, characterized in that it is made of the following raw materials in parts by weight: 18-22 parts of astragalus, 8-10 parts of heterophylla, 13-17 parts of Agrimony, and 10-14 parts of Rehmannia glutinosa 13-17 parts of angelica, 18-22 parts of jujube, 18-22 parts of black sesame, 13-17 parts of Polygonum multiflorum, 18-22 parts of Codonopsis pilosula, 10-14 parts of donkey-hide gelatin, 8-10 parts of tangerine peel, 8- 10 parts, 6-8 parts of medlar, 6-8 parts of licorice.
所述的治疗缺铁性贫血的中药制剂,其优选是:由如下重量份的原料药制成:黄芪20份、太子参9份、仙鹤草15份、熟地黄12份、当归15份、大枣20份、黑芝麻20份、何首乌15份、党参20份、阿胶12份、陈皮9份、香附9份、枸杞子7份、甘草7份。 The traditional Chinese medicine preparation for treating iron deficiency anemia is preferably: made of the following crude drugs in parts by weight: 20 parts of astragalus, 9 parts of heterophylla, 15 parts of agrimony, 12 parts of rehmannia glutinosa, 15 parts of angelica, 20 parts of jujube, 20 parts of black sesame, 15 parts of Polygonum multiflorum, 20 parts of Codonopsis pilosula, 12 parts of donkey-hide gelatin, 9 parts of tangerine peel, 9 parts of Cyperus cyperi, 7 parts of medlar, and 7 parts of licorice.
所述的治疗缺铁性贫血的中药制剂的制备方法,包括以下步骤:按照所述重量份数称取各原料药,将称取好的各原料药混合、杀菌后装袋即可。 The preparation method of the traditional Chinese medicine preparation for treating iron-deficiency anemia comprises the following steps: weighing the raw materials according to the weight parts, mixing the weighed raw materials, sterilizing and packing into bags.
用法及用量:将制成的中药制剂加适量水煎煮,加热至沸点,煎煮30-50分钟,过滤得药液,用此方法连续煎煮三次,将三次煎煮所得药液合并,平均分为三份,患者每天早、中、晚各服用一份;15天为一个疗程。 Usage and dosage: Add proper amount of water to decoct the prepared traditional Chinese medicine preparation, heat to boiling point, decoct for 30-50 minutes, filter to obtain the medicinal liquid, use this method to decoct three times continuously, combine the medicinal liquid obtained from the three decoctions, and average It is divided into three parts, and patients take one part in the morning, noon and evening each day; 15 days is a course of treatment.
本发明的各原料药的药用性能如下: The medicinal properties of each crude drug of the present invention are as follows:
黄芪:性味归经:甘,微温,归肺、脾、肝、肾经;功效:补齐固表,托疮生肌。 Radix Astragali: meridian distribution of property and flavor: sweet, slightly warm, returns to lung, spleen, liver, kidney meridians; efficacy: tonifies and solidifies the surface, heals sores and promotes granulation.
太子参:性味归经:甘、微苦,平,归脾、肺经;功效:益气健脾,生津润肺。 Radix Pseudostellariae: Meridian distribution of property and flavor: sweet, slightly bitter, flat, returns to the spleen and lung meridians; efficacy: nourishing qi and invigorating the spleen, promoting body fluid and moistening the lungs.
仙鹤草:性味归经:苦、涩、平,归心、肝经;功效:收敛止血,截疟,止痢,解毒。 Agrimony: Meridian distribution of property and flavor: bitter, astringent, flat, heart-guiding, Liver Channel; Efficacy: astringent to stop bleeding, stop malaria, stop dysentery, detoxify.
熟地黄:性味归经:甘,微温,归肝、肾经;功效:滋阴补血,益精填髓。 Rehmannia glutinosa: Meridian distribution of property and flavor: sweet, slightly warm, returns to liver and kidney meridians; efficacy: nourishing yin and blood, nourishing essence and filling marrow.
当归:性味归经:甘、辛,温,归肝、心、脾经;功效:补血活血,调经止痛,润肠通便。 Angelica: meridian distribution of property and flavor: sweet, pungent, warm, returns to liver, heart, spleen meridian; efficacy: nourishing blood and promoting blood circulation, regulating menstruation and relieving pain, moistening intestines and laxative.
大枣:性味归经:甘,温,归脾、胃经;功效:补脾益气,养心安神。 Jujube: meridian distribution of property and flavor: sweet, warm, spleen and stomach meridians; efficacy: nourishing the spleen and replenishing qi, nourishing the heart and calming the nerves.
黑芝麻:性味归经:甘,平,归肝、肾、大肠经;功效:补肝肾,益精血,润肠燥。 Black Sesame: Meridian distribution of nature and flavor: sweet, flat, returns to liver, kidney, large intestine meridian; efficacy: nourishing liver and kidney, nourishing essence and blood, moistening intestines and dryness.
何首乌:性味归经:苦、甘、涩、温,归肝、心、肾经;功效:解毒,消痈,润肠通便。 Radix Polygoni Multiflori: Meridian distribution of property and flavor: bitter, sweet, astringent, warm, returns to liver, heart, kidney meridian; Efficacy: detoxification, disappearing carbuncle, moistening bowel and laxative.
党参:性味归经:甘、平,归脾、肺经;功效:补中益气、健脾益肺。 Radix Codonopsis: meridian distribution of property and flavor: sweet, flat, spleen, lung meridian; efficacy: invigorating the middle and replenishing qi, invigorating the spleen and benefiting the lung.
阿胶:性味归经:平,甘,归肺、肾、肝经;功效:补血,止血,滋阴润肠。 Donkey-hide gelatin: meridian distribution of nature and flavor: flat, sweet, returns to lung, kidney, liver meridian; efficacy: nourishing blood, stopping bleeding, nourishing yin and moistening intestines.
陈皮:性味归经:苦、辛、温,归肺、脾经;功效:理气健脾、燥湿化痰。 Tangerine peel: meridian distribution of property and flavor: bitter, pungent, warm, returns to lung, spleen meridian; efficacy: regulating qi and invigorating spleen, drying dampness and resolving phlegm.
香附:性味归经:辛、微苦、微甘,平,归肝、脾、三焦经;功效:行气解郁,调经止痛。 Rhizoma Rhizoma Rhizoma Cyperae: meridian distribution of property and flavor: pungent, slightly bitter, slightly sweet, flat, returns liver, spleen, triple burner meridian; effect: promoting qi circulation to relieve depression, regulating menstruation and relieving pain.
枸杞子:性味归经:甘、平,归肝、肾经;功效:滋补肝肾,益精明目。 Fructus Lycium barbarum: meridian distribution of property and flavor: sweet, flat, returns to liver and kidney meridians; efficacy: nourishing liver and kidney, benefiting energy and improving eyesight.
甘草:性味归经:甘、平,归心、肺、脾、胃经;功效:补脾益气,清热解毒,祛痰止咳,缓急止痛,调和诸药。 Licorice Root: meridians of nature and flavor: sweet, flat, heart-guiding, lung, spleen, stomach meridians; efficacy: invigorating the spleen and replenishing qi, clearing heat and detoxifying, eliminating phlegm and relieving cough, relieving spasm and relieving pain, harmonizing various medicines.
本发明用上述各原料药及其配比所制成的中药制剂,具有益气养血、补肾填精、促进造血功能的作用,从而达到治疗缺铁性贫血的目的。 The traditional Chinese medicine preparation prepared by using the above raw materials and their proportions has the functions of nourishing qi and blood, tonifying kidney and replenishing essence, and promoting hematopoietic function, so as to achieve the purpose of treating iron-deficiency anemia.
本发明与现有技术相比所具有的有益效果是:本发明具有标本兼治,疗效显著,副作用小的优点;经临床验证,本发明治疗缺铁性贫血有效率为97%。 Compared with the prior art, the present invention has the beneficial effects that: the present invention has the advantages of treating both symptoms and root causes, significant curative effect, and less side effects; clinical verification shows that the effective rate of the present invention for treating iron deficiency anemia is 97%.
具体实施方式 Detailed ways
实施例1: Example 1:
一种治疗缺铁性贫血的中药制剂,由如下重量份的原料药制成:黄芪20份、太子参9份、仙鹤草15份、熟地黄12份、当归15份、大枣20份、黑芝麻20份、何首乌15份、党参20份、阿胶12份、陈皮9份、香附9份、枸杞子7份、甘草7份。 A traditional Chinese medicine preparation for treating iron-deficiency anemia, which is prepared from the following raw materials in parts by weight: 20 parts of astragalus, 9 parts of heterophylla, 15 parts of agrimony, 12 parts of rehmannia glutinosa, 15 parts of angelica, 20 parts of jujube, black Sesame 20 parts, Polygonum multiflorum 15 parts, Codonopsis 20 parts, Ejiao 12 parts, Tangerine peel 9 parts, Cyperus cyperi 9 parts, Lycium barbarum 7 parts, Licorice 7 parts.
所述的治疗缺铁性贫血的中药制剂的制备方法,包括以下步骤:按照所述重量份数称取各原料药,将称取好的各原料药混合、杀菌后装袋即可。 The preparation method of the traditional Chinese medicine preparation for treating iron-deficiency anemia comprises the following steps: weighing the raw materials according to the weight parts, mixing the weighed raw materials, sterilizing and packing into bags.
实施例2: Example 2:
一种治疗缺铁性贫血的中药制剂,由如下重量份的原料药制成:黄芪18份、太子参8份、仙鹤草13份、熟地黄10份、当归13份、大枣18份、黑芝麻18份、何首乌13份、党参18份、阿胶10份、陈皮8份、香附8份、枸杞子6份、甘草6份。 A traditional Chinese medicine preparation for treating iron-deficiency anemia, which is prepared from the following raw materials in parts by weight: 18 parts of astragalus, 8 parts of heterophylla, 13 parts of agrimony, 10 parts of rehmannia glutinosa, 13 parts of angelica, 18 parts of jujube, black 18 parts of sesame, 13 parts of Polygonum multiflorum, 18 parts of Codonopsis, 10 parts of donkey-hide gelatin, 8 parts of tangerine peel, 8 parts of Cyperus, 6 parts of medlar, and 6 parts of licorice.
所述的治疗缺铁性贫血的中药制剂的制备方法,包括以下步骤:按照所述重量份数称取各原料药,将称取好的各原料药混合、杀菌后装袋即可。 The preparation method of the traditional Chinese medicine preparation for treating iron-deficiency anemia comprises the following steps: weighing the raw materials according to the weight parts, mixing the weighed raw materials, sterilizing and packing into bags.
实施例3: Example 3:
一种治疗缺铁性贫血的中药制剂,由如下重量份的原料药制成:黄芪22份、太子参10份、仙鹤草17份、熟地黄14份、当归17份、大枣22份、黑芝麻22份、何首乌17份、党参22份、阿胶14份、陈皮10份、香附10份、枸杞子8份、甘草8份。 A traditional Chinese medicine preparation for treating iron-deficiency anemia, which is prepared from the following raw materials in parts by weight: 22 parts of astragalus, 10 parts of heterophylla, 17 parts of agrimony, 14 parts of rehmannia glutinosa, 17 parts of angelica, 22 parts of jujube, black 22 parts of sesame, 17 parts of Polygonum multiflorum, 22 parts of Codonopsis pilosula, 14 parts of donkey-hide gelatin, 10 parts of tangerine peel, 10 parts of Cyperus cyperi, 8 parts of medlar, and 8 parts of licorice.
所述的治疗缺铁性贫血的中药制剂的制备方法,包括以下步骤:按照所述重量份数称取各原料药,将称取好的各原料药混合、杀菌后装袋即可。 The preparation method of the traditional Chinese medicine preparation for treating iron-deficiency anemia comprises the following steps: weighing the raw materials according to the weight parts, mixing the weighed raw materials, sterilizing and packing into bags.
实验例: Experimental example:
一、临床资料:采用本发明治疗缺铁性贫血患者38例,其中男16例,女22例,年龄最大43岁,年龄最小6岁。 1. Clinical data: The present invention was used to treat 38 patients with iron deficiency anemia, including 16 males and 22 females, the oldest being 43 years old and the youngest 6 years old.
二、临床症状:乏力、易倦、头晕、头痛、眼花、耳鸣、心悸、气短、纳差等。 2. Clinical symptoms: fatigue, tiredness, dizziness, headache, vertigo, tinnitus, palpitations, shortness of breath, anorexia, etc.
三、治疗方法:将制成的中药制剂加适量水煎煮,加热至沸点,煎煮30-50分钟,过滤得药液,用此方法连续煎煮三次,将三次煎煮所得药液合并,平均分为三份,患者每天早、中、晚各服用一份;15天为一个疗程。 3. Treatment method: decoct the prepared traditional Chinese medicine preparation with appropriate amount of water, heat to boiling point, decoct for 30-50 minutes, filter to obtain the medicinal liquid, use this method to decoct three times continuously, combine the medicinal liquid obtained from the three decoctions, It is divided into three parts on average, and patients take one part each morning, noon and night; 15 days is a course of treatment.
四、疗效评价标准: 4. Criteria for curative effect evaluation:
治愈:症状消失,实验检查正常; Cured: Symptoms disappear, laboratory tests are normal;
好转:症状明显改善,实验室检查有改善; Improvement: Symptoms have improved significantly, and laboratory tests have improved;
未愈:症状未改善或恶化者,实验室检查无改善。 Unhealed: If the symptoms do not improve or worsen, there is no improvement in laboratory tests.
五、典型病例: 5. Typical cases:
1、周某某,女,26岁,农民,患缺铁性贫血3年,症状表现为头晕、心悸、乏力、纳差等;服用过多种药物未治愈,服用本发明的中药制剂一个疗程症状明显改善,服用三个疗程痊愈,随访2年,未复发。 1. Zhou Moumou, female, 26 years old, farmer, has suffered from iron deficiency anemia for 3 years, and her symptoms are dizziness, palpitation, fatigue, anorexia, etc.; she has not been cured after taking a variety of medicines, and takes the traditional Chinese medicine preparation of the present invention for a course of treatment Symptoms were obviously improved, and he recovered after taking three courses of treatment, followed up for 2 years, and there was no recurrence.
2、卢某,女,39岁,农民,患缺铁性贫血6年,症状表现为乏力、头晕、心悸、气短等;服用过多种药物未治愈,服用本发明的中药制剂两个疗程症状明显改善,服用四个疗程痊愈;随访1年,未复发。 2. Lu, female, 39 years old, farmer, suffered from iron-deficiency anemia for 6 years, and her symptoms showed as fatigue, dizziness, heart palpitations, shortness of breath, etc.; she had not been cured after taking a variety of medicines, and she took the Chinese medicine preparation of the present invention for two courses of symptoms Significantly improved, and took four courses of treatment to recover from illness; follow up a case by regular visits to 1 year, no recurrence.
3、汪某,男,14岁,学生,患缺铁性贫血1年,症状表现为乏力、易倦、头痛、耳鸣、纳差等;服用过多种药物未治愈,服用本发明的中药制剂两个疗程症状明显改善,服用四个疗程痊愈,随访2年,未复发。 3. Wang Mou, male, 14 years old, student, suffered from iron deficiency anemia for 1 year, and the symptoms showed as fatigue, tiredness, headache, tinnitus, anorexia, etc.; after taking many kinds of medicines but not cured, he took the traditional Chinese medicine preparation of the present invention The symptoms of two courses of treatment were obviously improved, and after taking four courses of treatment, the symptoms were cured, followed up for 2 years, and there was no recurrence.
六、治疗结果: 6. Treatment results:
采用本发明治疗缺铁性贫血患者38例,经过1-4个疗程的治疗,其中治愈33例,好转4例,未愈1例,治愈率为86%,有效率为97%;结果表明,本发明对治疗缺铁性贫血具有标本兼治,疗效显著,副作用小的优点。 Adopt the present invention to treat 38 cases of patients with iron deficiency anemia, through 1-4 courses of treatment, wherein 33 cases were cured, 4 cases took a turn for the better, and 1 case was unhealed, the cure rate was 86%, and the effective rate was 97%; the results showed that, The invention has the advantages of treating both symptoms and root causes of iron deficiency anemia, remarkable curative effect and less side effects.
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| CN1167456C (en) * | 2002-11-28 | 2004-09-22 | 贵阳德昌祥药业有限公司 | Compound donkey-hide gelatin enriching blood ointment |
| CN101062195A (en) * | 2007-05-21 | 2007-10-31 | 王军 | Fleece-flower root oral liquid for enriching blood |
| CN101536780B (en) * | 2009-04-24 | 2012-10-17 | 山东华信制药集团股份有限公司 | A kind of gel tonic food and health food |
-
2013
- 2013-02-13 CN CN201310050450.7A patent/CN103055085B/en not_active Expired - Fee Related
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