CN1089142A - Pine needle hypoglycemic oral liquid - Google Patents

Abstract

Pine needle hypoglycemic oral liquid is a kind of pure Chinese medicinal preparation, and it is a kind of have health care and new type natural blood sugar reducing health therapeutic agent for the treatment of.

Main component is fresh Folium Pini Cacumen Platycladi (Cacumen Biotae) etc.It is by first liquid: Folium Pini, Cacumen Platycladi (Cacumen Biotae), extract solution of bamboo leaves; Second liquid: extracting solution such as the Radix Astragali, Rhizoma Dioscoreae, Fructus Lycii, Radix Glycyrrhizae, Fructus Mume, Radix Ophiopogonis, the Radix Rehmanniae, Fructus Schisandrae Chinensis, Radix Puerariae; Flavoring agent: compositions such as xylitol, stevioside, Mel.First and second liang of liquid use magnetic water (permanent magnetic field intensity is 1800-2200 oersteds) to decoct respectively, are concentrated into finite concentration, and relative density is respectively: 1.03-1.09/1.01-1.03.Handle through biofermentation, freezing, again through magnetic filtering (permanent magnetic field intensity is 1600-1800 oersteds), two liquid mix with flavoring agent.

Description

Pine needle hypoglycemic oral liquid

Pine needle hypoglycemic oral liquid is a kind of pure Chinese medicinal preparation.It is that the collection health care is the new type natural blood sugar reducing health therapeutic agent of one with treatment.

It is documented: pine is the length of hundred wood, Folium Pini is good medicine (Compendium of Material Medica) food Folium Pini energy life lengthening (Everyman's Science 1986(1): 7), can also treat numerous disease (" progress of Folium Pini ", the 1990.7(3 of school of Shenyang Pharmacy College)).Again according to the literature: Cortex Pini and Stigma Maydis can be treated diabetes (" side among the people " energy publishing house 1986), but because processing technique is too simple, and active substance is few, curative effect is relatively poor, simultaneously, because of containing the tannin height, stomach is had certain stimulation.And mouthfeel is very pained.Patient is difficult to oral, and again owing to Cortex Pini, the difficulty of drawing materials is not easy to mass production.

Purpose of the present invention, adopting draws materials is easy to Folium Pini etc., as primary raw material, through magnetic treatment, processing such as biofermentation, retrofit forms, active substance content height, treatment diabetes effect is remarkable, and mouthfeel is moderate, has tonic again, the effect of prevent diabetes.Diabetes are not the titles of certain single disease, but the sugar that human body causes owing to multiple reason, fat and protein metabolism disorder, wherein tangible change also takes place in metabolism of trace elements, is a plurality of systems of principal character with the hyperglycemia, stolen goods organ in a plurality of, a kind of syndrome that suffers damage.

Feature of the present invention mainly is that Folium Bambusae is a primary raw material with secondary product of forestry Folium Pini, Cacumen Platycladi (Cacumen Biotae) that medicinal effects is arranged, to control kidney, settling five organs, blood circulation promoting and blood stasis dispelling, blood circulation promoting increases that diabetes are had the be rich in zinc, chromium, selenic bioactive substance of special role is main purpose.Pine, cypress, Folium Bambusae ratio are: 4-6/0-3/0-2.Extract concentration, relative density are that 1.02-1.09 believes than the high 4-5 of Cortex Pini extract concentration, and promptly every milliliter contains crude drug 2-4 gram.

The compatibility raw material has Radix Puerariae, Radix Glycyrrhizae, the Radix Astragali, Fructus Lycii, Fructus Mume, Rhizoma Dioscoreae, the Radix Rehmanniae, Radix Ophiopogonis, Fructus Schisandrae Chinensis etc., and with QI invigorating, lung heat clearing, spleen, kidney three dirty heat are purpose.Its ratio is: 2-3/2-3/1-2/0.8-1.0/0.5-1.0/1/1/1/0.5-1 extract concentration, relative density are 1.01-1.03.

Two of feature of the present invention, as deastringent agent, consumption is the 5-10% of Folium Pini and Cacumen Platycladi total amount with Semen sojae atricolor (or Semen Glycines).Semen sojae atricolor contains rich in protein, and tannin a part of and in the extracting solution combines and precipitates, and removes by filter, and another part helps treatment of diabetes as increasing Protein content in the oral liquid.

Three of feature of the present invention adopts edible magnetic water to decoct water as extracting.Permanent magnetic field intensity is the 1800-2200 oersted.It is the 1600-1800 oersted that permanent magnetic field filters magnetic field intensity.After magnetic treatment, this medication is imitated significantly, and the effect of the kidney invigorating and essence nourishing is arranged.

Four of feature of the present invention adopts biofermentation to handle, and used yeast is the edible yeast powder, and consumption is the 0.5-1.5% of extracting solution total amount, and after fermentation process, this medicine has increased the content of effective ingredient and polysaccharide, and tannin reduces, and has improved curative effect, has improved mouthfeel.

Five of feature of the present invention, used flavoring agent is xylitol, stevioside and Mel.Xylitol is adjusted outside the palatability except strengthening this medicine and sugariness, to the treatment diabetes, tangible auxiliary curative effect is arranged also, and its ratio is 2-4/0-0.2/0.5-3.

In sum, pine needle hypoglycemic oral liquid of the present invention is to be primary raw material with fresh Folium Pini, Cacumen Platycladi (Cacumen Biotae), Folium Bambusae, draws materials easily, and wide material sources are convenient to mass production.

The Pinus tabuliformis in known North China (Pinus tabulaeformis), southern Pinus massoniana Lamb (P.massoniana), the pinus yunnanensis faranch in Yunnan (P.yunnanensis), the leaf of the Pinus koraiensis in northeast (P.koraiensis), the leaf of Cacumen Platycladi (Platycladus orientalis) garden cypress (Sabina Chinensis), leaves such as Phyllostachys pubescens Mazei ex H.de Lebaie, firm bamboo all can be taked to be used as medicine.

This medicine is sent out alcohol through biology, and after handled in magnetic field, mouthfeel was greatly taken on a new look, little hardship, and palatability is good, and patient is oral easily.To the II diabetes patient, evident in efficacy, total effective rate is about 85%.Simultaneously, this medicine is for hyperlipidemia, hypertension, and diseases such as sexual disorder also have curative effect preferably.Middle-aged and elderly people is taken for a long time, and promoting blood circulation to remove obstruction in the collateral is arranged, and strengthens the human immunologic function, the effect of prevention and health care.

Pine needle hypoglycemic oral liquid by the first and second two kinds of Chinese medicine extract, is formed with flavoring agent.Its production technology is as follows:

First liquid: 1. in proportion, take fresh Folium Pini, Cacumen Platycladi (Cacumen Biotae), Folium Bambusae, remove the skill bar, Lao Ye does not have the leaf that goes mouldy.

2. clean, with edible flushing with clean water 2-3 time, filter is done.

3. pulverize:, leaf is cut into the long segment of 2-3cm with the pulverizer chopping.

4. decoct: add magnetic water (permanent magnetic field intensity is the 1800-2200 oersted) 2-3 doubly, level mutually to the water surface in material.Heating decocts, and waits water to boil back 1 hour, and extracting solution is poured out.

5. concentrate: add Semen sojae atricolor (or Semen Glycines), consumption is the 5-10% of pine and cypress Folium Bambusae total amount, and it is concentrated to uncap, and concentration to relative density is 1.02-1.09.

6. send out alcohol: under 37 ℃ of conditions, with the edible yeast powder, consumption is that the 0.5-1% of extracting solution total amount carried out fermentation process 24 hours.

7. freezing, with flavoring agent: xylitol, stevioside, Mel, its ratio is: 2-4/0-0.2/0.5-3, stir, put to 4 ℃ of freezing 10-15 days.

8. filter: get supernatant, filter, filtrate is transparent brownish black, i.e. first liquid.

Second liquid: 1. get raw material, in proportion, take by weighing Radix Puerariae, Radix Glycyrrhizae, the Radix Astragali, Fructus Lycii, Fructus Mume, Rhizoma Dioscoreae, the Radix Rehmanniae, Radix Ophiopogonis, Fructus Schisandrae Chinensis etc.

2. decoct: add magnetic water (with first liquid) and material to level, heating, water boiled back 1 hour, and extracting liquid filtering is poured out; Again former medicine is extracted for the second time, filtrate is merged.

3. concentrate: under 60 ℃ of coarse vacuum conditions, being concentrated into relative density is 1.01-1.03.

4. freezing: as to put to 4 ℃ of freezing 1-3 days.

5. filter: get supernatant liquid filtering.Filtrate is brown yellow transparent liquid, i.e. second liquid.

First and second liang of liquid are merged, filter through permanent magnetism, magnetic field intensity is the 1600-1800 oersted, and relative density is that 1.03-1.07 is dark brown red transparency liquid, i.e. pine needle hypoglycemic oral liquid.

Embodiment 1-example 3

Take fresh Folium Pini, Cacumen Platycladi (Cacumen Biotae), Folium Bambusae reach raw materials such as Radix Puerariae, Radix Glycyrrhizae, press routine raw material and feed intake cleanly, add magnetic water (permanent magnetism intensity 1800 oersteds), heating decocts, water boiled back 1 hour, poured out extract, (wherein first liquid adds Semen sojae atricolor or Semen Glycines), consumption be the raw material total amount 6%) uncap concentrated, to concentration be certain relative density (wherein first liquid is with the edible yeast powder, and consumption is 1% of an extracting solution total amount, fermentation process 24 in a small amount) then, freezing (4 ℃) 1-15 days get supernatant liquid filtering.

First and second liang of liquid mix, and are dark brown red transparency liquid through magnetic filtering (permanent magnetic field intensity is 1800 oersteds) filtrate again, and the little hardship of mouthfeel, relative density are 1.03-1.07, and putting for a long time has precipitation approximately.

Claims (5)

1, pine needle hypoglycemic oral liquid, its principal character are to be primary raw material with the secondary product of forestry Folium Pini that medicinal effects is arranged, Cacumen Platycladi (Cacumen Biotae) Folium Bambusae etc., and its ratio is 4-6/0-3/0-2.Extracting solution is dense-contract to relative density be 1.02-1.09.

The compatibility raw material has: Radix Puerariae, Radix Glycyrrhizae, the Radix Astragali, Fructus Lycii, Fructus Mume, Rhizoma Dioscoreae, the Radix Rehmanniae, Radix Ophiopogonis, Fructus Schisandrae Chinensis etc., its ratio is 1.01-1.03 for the 2-3/2-3/1-2/0.8-1.0/0.5-1.0/1/1/1/0.5-1 extracting solution is concentrated into relative density.

2, described according to claim 1, pine needle hypoglycemic oral liquid is characterized in that with Semen sojae atricolor (or Semen Glycines) as deastringent agent, consumption is the 5-10% of pine and cypress Folium Bambusae total amount.

3, described according to right 1.2, pine needle hypoglycemic oral liquid, its feature institute water be, the magnetic water that permanent magnetism is handled, and its magnetic field intensity is the 1800-2200 oersted, and permanent magnetic field filters, and magnetic field intensity is the 1600-1800 oersted.

4, described according to right 1.2, pine needle hypoglycemic oral liquid is characterized by fermentation process, and used yeast is the edible yeast powder, and consumption is extracting solution total amount 0.5-1.5%.

5, described according to right 1.2, pine needle hypoglycemic oral liquid, its feature, flavoring agent is xylitol, stevioside, Mel, its ratio is 2-4/0-0.2/0.5-3.