CN108906199A - A kind of grinding device of domperidone bulk pharmaceutical chemicals - Google Patents

A kind of grinding device of domperidone bulk pharmaceutical chemicals Download PDF

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Publication number
CN108906199A
CN108906199A CN201810714963.6A CN201810714963A CN108906199A CN 108906199 A CN108906199 A CN 108906199A CN 201810714963 A CN201810714963 A CN 201810714963A CN 108906199 A CN108906199 A CN 108906199A
Authority
CN
China
Prior art keywords
inner cavity
feeding warehouse
welded
wall
bottom wall
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810714963.6A
Other languages
Chinese (zh)
Inventor
王玉斌
张英
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanjing La Aifu Pharmaceutical Technology Co Ltd
Original Assignee
Nanjing La Aifu Pharmaceutical Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanjing La Aifu Pharmaceutical Technology Co Ltd filed Critical Nanjing La Aifu Pharmaceutical Technology Co Ltd
Priority to CN201810714963.6A priority Critical patent/CN108906199A/en
Publication of CN108906199A publication Critical patent/CN108906199A/en
Pending legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C4/00Crushing or disintegrating by roller mills
    • B02C4/02Crushing or disintegrating by roller mills with two or more rollers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C23/00Auxiliary methods or auxiliary devices or accessories specially adapted for crushing or disintegrating not provided for in preceding groups or not specially adapted to apparatus covered by a single preceding group
    • B02C23/08Separating or sorting of material, associated with crushing or disintegrating
    • B02C23/10Separating or sorting of material, associated with crushing or disintegrating with separator arranged in discharge path of crushing or disintegrating zone
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C23/00Auxiliary methods or auxiliary devices or accessories specially adapted for crushing or disintegrating not provided for in preceding groups or not specially adapted to apparatus covered by a single preceding group
    • B02C23/18Adding fluid, other than for crushing or disintegrating by fluid energy
    • B02C23/20Adding fluid, other than for crushing or disintegrating by fluid energy after crushing or disintegrating
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C4/00Crushing or disintegrating by roller mills
    • B02C4/28Details
    • B02C4/40Detachers, e.g. scrapers

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  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Crushing And Grinding (AREA)
  • Catching Or Destruction (AREA)

Abstract

The invention patent discloses a kind of grinding device of domperidone bulk pharmaceutical chemicals of medicament disintegrating engineering device technique field, including device noumenon, the top of device noumenon is welded with feeding warehouse, the top of feeding warehouse is welded with the storehouse that feeds intake, the right wall of feeding warehouse is connected with baffle, the inner cavity top of device noumenon is welded with crushing bin, there is crushing wheel in inner cavity of crushing bin or so by shaft radially installed, bottom wall of inner cavity of crushing bin or so is bolted with scraper plate, the bottom wall of crushing bin is welded with filtering cabin, the bottom wall of inner cavity of filtering cabin is bolted with sieve, the right wall lower part of filtering cabin is provided with discharge hole, the right wall lower weld of filtering cabin has slide plate, the roof of slide plate is provided with sliding slot, the bottom wall of sliding slot is provided with sieve pore, the present apparatus is easy to operate, it is easy to use, charging rate is controllable, effectively reduce the waste of medicinal powder, reduce production cost.

Description

A kind of grinding device of domperidone bulk pharmaceutical chemicals
Technical field
The invention patent discloses a kind of grinding device of domperidone bulk pharmaceutical chemicals, and specially medicament disintegrating device technique is led Domain.
Background technique
Domperidone is benzimidazoles chemical combination-object, has the movement of stronger rush stomach and antiemetic effect, can reinforce under oesophagus Portion's sphincter tone prevents stomach-esophageal reflux, enhances peristole, promotes gastric emptying, coordinates stomach and uodenal movement, inhibits Nausea and vomiting, and it is effectively prevented bile regurgitation, do not influence gastric secretion.This product is periphery dopamine-receptor antagonist, directly It blocks the dopamine receptor of stomach and intestine and presents and promote stomach movement effect.The wriggling of esophagus and of esophageal sphincter can be enhanced Power.Since it is poor to the penetration of blood-brain barrier, to intracerebral dopamine receptor almost without antagonism, therefore can exclude spirit and The side effect of nervous centralis, domperidone need to crush raw medicine when carrying out pharmacy, be convenient for pharmacy, such as Chinese invention Shen Please number for CN201711287748.4 propose a kind of powder medicine drying and crushing device, in use, due to drug from The extruding that crushing wheel and two groups of crushing wheels are hit by falling bodies, will cause jumping out for drug, leaves crushing wheel crush-zone, drug is fallen When entering sieve, the whereabouts of medicinal powder can be stopped, so that medicinal powder rests in sieve, the extruding of this external cause crushing wheel causes medicinal powder viscous Knot causes the waste of medicinal powder in crushing wheel outer wall.
Patent of invention content
The grinding device for being designed to provide a kind of domperidone bulk pharmaceutical chemicals of the invention patent, to solve above-mentioned background technique The medicinal powder of middle proposition rests on the problem of sieve traditional Chinese medicine powder is easily bonded in the outer wall of crushing wheel.
To achieve the above object, the invention patent provides the following technical solutions:A kind of crushing dress of domperidone bulk pharmaceutical chemicals It sets, including device noumenon, the top of described device ontology is welded with feeding warehouse, and the lower part of the feeding warehouse is located at device noumenon Inner cavity, the top of the feeding warehouse are welded with the storehouse that feeds intake, and the feeding warehouse is connected to the inner cavity of device noumenon and the storehouse that feeds intake respectively, The right wall of the feeding warehouse is connected with baffle, and the right wall of feeding warehouse is run through in the left end of the baffle, the left end of the baffle with into The inner cavity left wall of feed bin is clamped, and the inner cavity top of described device ontology is welded with crushing bin, and inner cavity of the crushing bin or so is equal There is crushing wheel by shaft radially installed, the bottom wall of inner cavity or so of the crushing bin is bolted with scraper plate, the scraper plate and crushing The outer wall of wheel contacts, and the bottom wall of the crushing bin is welded with filtering cabin, and the bottom wall of inner cavity of the filtering cabin is bolted with sieve, described The right wall lower part of filtering cabin is provided with discharge hole, and the bottom wall of the filtering cabin and crushing bin is provided with through-hole, the right side of the filtering cabin Wall lower weld has slide plate, and the right end of the slide plate runs through the right wall of device noumenon, and the roof of the slide plate is provided with sliding slot, described The bottom wall of sliding slot is provided with sieve pore, and the right wall lower part of described device ontology is connected with raw material collection box, the raw material by weldment Collection box is connected to sliding slot, and the left and right outer wall lower part of described device ontology is respectively welded escape pipe and air inlet pipe, the air inlet Pipe is located at the lower part of raw material collection box, and the left end of the escape pipe is welded with exhaust pipe, the rear end of the exhaust pipe and air blower Air outlet connection.
Preferably, the inner cavity left wall of the baffle is provided with blowpit, and blowpit is located at baffle and feeding warehouse left part is clamped The lower part at place.
Preferably, the bottom wall of inner cavity radial cross-section of described device ontology is U-shaped.
Preferably, the scraper plate is nylon66 fiber scraper plate.
Preferably, the crushing wheel is smooth surface crushing wheel.
Compared with prior art, the beneficial effect of the invention patent is:
1)Baffle and feeding warehouse is arranged in the present apparatus, by the opening and closing degree of baffle, controls charging rate, feeding warehouse is located at crushing wheel Top, reduce the probability that jumps out of drug;
2)Inclined filtering cabin, slide plate and raw material collection box are set, and when so that drug and medicinal powder falling into sieve pore, drug passes through self weight And inertia, so that drug rolls the sliding slot into slide plate, then drug is scrolled into raw material collection box, and drug is avoided to stop medicinal powder Pass through, reduces the waste of medicinal powder;
3)Air blower, exhaust pipe and escape pipe are set, using principle of negative pressure, so that medicinal powder is left by escape pipe and exhaust pipe The inner cavity of device noumenon, medicinal powder collection is more complete, avoids medicinal powder from being bonded in the inner cavity of device noumenon, reduces the waste of medicinal powder;
4)Scraper plate is set, using the rotation of crushing wheel, so that scraper plate scrapes the medicinal powder for being bonded in crushing wheel outer wall, present apparatus behaviour Make simply, easy to use, charging rate is controllable, effectively reduces the waste of medicinal powder, reduces production cost.
Detailed description of the invention
Fig. 1 is the invention patent structural schematic diagram;
Fig. 2 is the invention patent slide plate right side view;
Fig. 3 is the invention patent feeding warehouse elevational cross-sectional view;
Fig. 4 is the invention patent device noumenon right side view.
In figure:1 device noumenon, 2 feeding warehouses, 3 feed intake storehouse, 4 baffles, 5 crushing bins, 6 crushing wheels, 7 filtering cabins, 71 sieves, 72 discharge holes, 8 slide plates, 81 sliding slots, 82 sieve pores, 9 raw material collection boxes, 10 air inlet pipe, 11 escape pipes, 12 exhaust pipes, 13 air blowers, 14 scraper plates.
Specific embodiment
Below in conjunction with the attached drawing in the invention patent embodiment, the technical solution in the invention patent embodiment is carried out Clearly and completely describing, it is clear that described embodiment is only the invention patent a part of the embodiment, rather than whole Embodiment.Based on the embodiment in the invention patent, those of ordinary skill in the art are without making creative work Every other embodiment obtained belongs to the range of the invention patent protection.
Fig. 1-4 is please referred to, the invention patent provides a kind of technical solution:A kind of grinding device of domperidone bulk pharmaceutical chemicals, Including device noumenon 1, the top of device noumenon 1 is welded with feeding warehouse 2, and the lower part of feeding warehouse 2 is located at the inner cavity of device noumenon 1, The top of feeding warehouse 2 is welded with the storehouse 3 that feeds intake, and feeding warehouse 2 is connected to the inner cavity of device noumenon 1 and the storehouse 3 that feeds intake respectively, feeding warehouse 2 Right wall be connected with baffle 4, the right wall of feeding warehouse 2, the left end of baffle 4 and the inner cavity left wall of feeding warehouse 2 are run through in the left end of baffle 4 Clamping, the inner cavity top of device noumenon 1 are welded with crushing bin 4, and there is powder in inner cavity of crushing bin 4 or so by shaft radially installed Broken wheel 6, bottom wall of inner cavity of crushing bin 5 or so is bolted with scraper plate 14, and scraper plate 14 is contacted with the outer wall of crushing wheel 6, crushing bin 5 Bottom wall is welded with filtering cabin 7, and the bottom wall of inner cavity of filtering cabin 7 is bolted with sieve 71, and the right wall lower part of filtering cabin 7 is provided with discharge hole 72, the bottom wall of filtering cabin 7 and crushing bin 5 is provided with through-hole, and the right wall lower weld of filtering cabin 7 has slide plate 8, the right end of slide plate 8 Through the right wall of device noumenon 1, the roof of slide plate 8 is provided with sliding slot 81, and the bottom wall of sliding slot 81 is provided with sieve pore 82, device noumenon 1 Right wall lower part is connected with raw material collection box 9 by weldment, and raw material collection box 9 is connected to sliding slot 81, outside the left and right of device noumenon 1 Wall lower part is respectively welded escape pipe 11 and air inlet pipe 10, and air inlet pipe 10 is located at the lower part of raw material collection box 9, a left side for escape pipe 11 End is welded with exhaust pipe 12, and the rear end of exhaust pipe 12 is connect with the air outlet of air blower 13.
Wherein, the inner cavity left wall of baffle 4 is provided with blowpit, and blowpit is located at baffle 4 and 2 left part access section of feeding warehouse Blowpit is left by self weight and inertia convenient for drug in lower part, and when avoiding charging, drug falls into blowpit, causes baffle 4 can not Closure, the bottom wall of inner cavity radial cross-section of device noumenon 1 be it is U-shaped, be deposited in the middle part of 1 bottom wall of inner cavity of device noumenon convenient for medicinal powder, Medicinal powder is sucked out convenient for negative pressure, scraper plate 14 is nylon66 fiber scraper plate, and nylon66 fiber intensity is higher, and self-lubrication is excellent, and wearability is good, powder Broken wheel 6 is smooth surface crushing wheel, scrapes the medicinal powder of 6 outer wall of crushing wheel convenient for scraper plate 14.
Working principle:The shaft of two groups of crushing wheels 6 is engaged by gear, one group of shaft is connected by shaft coupling and motor Connect, drug to be comminuted poured into the storehouse 3 that feeds intake, start motor and air blower 13, pull baffle 4 so that the left end of baffle 4 from Driving the inner cavity left wall of feed bin 2 into, drug is entered in feeding warehouse 2 by the storehouse 3 that feeds intake, and then drug is fallen between two groups of crushing wheels 5, Two groups of incorgruous rotations of crushing wheel 5, drug are then crushed wheel 5 and roll crushing, but since drug leaves the inertia and two of feeding warehouse 2 The extruding of group crushing wheel 5 leaves the surface of two groups of crushing wheels 5 so that drug jumps out, and the bottom opening of feeding warehouse 2, which is located at, to be crushed The top of wheel 6 reenters in two groups of crushing wheels 6 and is crushed, be bonded in crushing wheel 6 so that major part jumps out drug and is blocked The medicinal powder of outer wall is scraped by scraper plate 14, and medicinal powder and a part of drug leave crushing bin 5 and enter in filtering cabin 7, falls in sieve 71 Surface, the drug on sieve 71 are tumbled by discharge port 72 into the sliding slot 81 in slide plate 8, the medicinal powder on sieve 71 The inner cavity for falling into device noumenon 1, with the rolling of drug, the medicinal powder for being bonded in drug substance surface falls into device noumenon by sieve pore 82 1 inner cavity, because of suction function, medicinal powder is entered in exhaust pipe 12 by escape pipe 11, with the air blast of air blower 13, so that medicinal powder It leaves exhaust pipe to be collected, drug is scrolled into raw material collection box 9 by sliding slot 81, facilitates continue to use when producing next time.
While there has been shown and described that the embodiment of the invention patent, for the ordinary skill in the art, It is understood that these embodiments can be carried out with a variety of variations in the case where not departing from the principle and spirit of the invention patent, repaired Change, replacement and variant, the range of the invention patent is defined by the appended claims and the equivalents thereof.

Claims (5)

1. a kind of grinding device of domperidone bulk pharmaceutical chemicals, including device noumenon(1), it is characterised in that:Described device ontology(1) Top be welded with feeding warehouse(2), the feeding warehouse(2)Lower part be located at device noumenon(1)Inner cavity, the feeding warehouse(2) Top be welded with the storehouse that feeds intake(3), the feeding warehouse(2)Respectively with device noumenon(1)With the storehouse that feeds intake(3)Inner cavity connection, institute State feeding warehouse(2)Right wall be connected with baffle(4), the baffle(4)Left end run through feeding warehouse(2)Right wall, the baffle (4)Left end and feeding warehouse(2)Inner cavity left wall clamping, described device ontology(1)Inner cavity top be welded with crushing bin(4), The crushing bin(4)Inner cavity or so have crushing wheel by shaft radially installed(6), the crushing bin(5)Bottom wall of inner cavity Left and right is bolted with scraper plate(14), the scraper plate(14)With crushing wheel(6)Outer wall contact, the crushing bin(5)Bottom wall weldering It is connected to filtering cabin(7), the filtering cabin(7)Bottom wall of inner cavity be bolted with sieve(71), the filtering cabin(7)Right wall lower part open There is discharge hole(72), the filtering cabin(7)And crushing bin(5)Bottom wall be provided with through-hole, the filtering cabin(7)Right wall lower part It is welded with slide plate(8), the slide plate(8)Right end run through device noumenon(1)Right wall, the slide plate(8)Roof be provided with cunning Slot(81), the sliding slot(81)Bottom wall be provided with sieve pore(82), described device ontology(1)Right wall lower part pass through weldment be clamped There is raw material collection box(9), the raw material collection box(9)With sliding slot(81)Connection, described device ontology(1)Left and right outer wall lower part It is respectively welded escape pipe(11)And air inlet pipe(10), the air inlet pipe(10)Positioned at raw material collection box(9)Lower part, it is described go out Tracheae(11)Left end be welded with exhaust pipe(12), the exhaust pipe(12)Rear end and air blower(13)Air outlet connection.
2. a kind of grinding device of domperidone bulk pharmaceutical chemicals according to claim 1, it is characterised in that:The baffle(4) Inner cavity left wall be provided with blowpit, and blowpit is located at baffle(4)With feeding warehouse(2)The lower part of left part access section.
3. a kind of grinding device of domperidone bulk pharmaceutical chemicals according to claim 1, it is characterised in that:Described device ontology (1)Bottom wall of inner cavity radial cross-section be it is U-shaped.
4. a kind of grinding device of domperidone bulk pharmaceutical chemicals according to claim 1, it is characterised in that:The scraper plate(14) For nylon66 fiber scraper plate.
5. a kind of grinding device of domperidone bulk pharmaceutical chemicals according to claim 1, it is characterised in that:The crushing wheel (6)For smooth surface crushing wheel.
CN201810714963.6A 2018-07-03 2018-07-03 A kind of grinding device of domperidone bulk pharmaceutical chemicals Pending CN108906199A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810714963.6A CN108906199A (en) 2018-07-03 2018-07-03 A kind of grinding device of domperidone bulk pharmaceutical chemicals

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810714963.6A CN108906199A (en) 2018-07-03 2018-07-03 A kind of grinding device of domperidone bulk pharmaceutical chemicals

Publications (1)

Publication Number Publication Date
CN108906199A true CN108906199A (en) 2018-11-30

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810714963.6A Pending CN108906199A (en) 2018-07-03 2018-07-03 A kind of grinding device of domperidone bulk pharmaceutical chemicals

Country Status (1)

Country Link
CN (1) CN108906199A (en)

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130175379A1 (en) * 2012-01-06 2013-07-11 Irwin Research And Development, Inc. Apparatus for Circulating Comminuted Materials
CN105665069A (en) * 2016-03-16 2016-06-15 杨露萍 Plastic particle smashing, screening and drying device
CN205323857U (en) * 2016-01-21 2016-06-22 首都师范大学 Screening device is smashed to soil
CN206526862U (en) * 2017-02-04 2017-09-29 福建省玛塔农业发展有限公司 Novel environment friendly oyster shell powder breaker and process units
CN107520033A (en) * 2017-09-20 2017-12-29 郑州大学 A kind of mobile damping type high accuracy milling device
CN206881193U (en) * 2017-04-22 2018-01-16 张坤 A kind of plant extract separator
CN107638931A (en) * 2017-09-19 2018-01-30 郑州大学 A kind of grinding processing equipment recycled for stalk
CN108176446A (en) * 2017-12-07 2018-06-19 蚌埠市宏大制药机械有限公司 A kind of powder medicine drying and crushing device
CN108176475A (en) * 2017-12-07 2018-06-19 蚌埠市宏大制药机械有限公司 A kind of pharmaceutical processing raw material reducing mechanism
CN209076754U (en) * 2018-07-03 2019-07-09 南京拉艾夫医药科技有限公司 A kind of grinding device of domperidone bulk pharmaceutical chemicals

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130175379A1 (en) * 2012-01-06 2013-07-11 Irwin Research And Development, Inc. Apparatus for Circulating Comminuted Materials
CN205323857U (en) * 2016-01-21 2016-06-22 首都师范大学 Screening device is smashed to soil
CN105665069A (en) * 2016-03-16 2016-06-15 杨露萍 Plastic particle smashing, screening and drying device
CN206526862U (en) * 2017-02-04 2017-09-29 福建省玛塔农业发展有限公司 Novel environment friendly oyster shell powder breaker and process units
CN206881193U (en) * 2017-04-22 2018-01-16 张坤 A kind of plant extract separator
CN107638931A (en) * 2017-09-19 2018-01-30 郑州大学 A kind of grinding processing equipment recycled for stalk
CN107520033A (en) * 2017-09-20 2017-12-29 郑州大学 A kind of mobile damping type high accuracy milling device
CN108176446A (en) * 2017-12-07 2018-06-19 蚌埠市宏大制药机械有限公司 A kind of powder medicine drying and crushing device
CN108176475A (en) * 2017-12-07 2018-06-19 蚌埠市宏大制药机械有限公司 A kind of pharmaceutical processing raw material reducing mechanism
CN209076754U (en) * 2018-07-03 2019-07-09 南京拉艾夫医药科技有限公司 A kind of grinding device of domperidone bulk pharmaceutical chemicals

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Application publication date: 20181130

RJ01 Rejection of invention patent application after publication