CN108904720A - A kind of drug of therapeutic radiation portacaval mucositis - Google Patents

A kind of drug of therapeutic radiation portacaval mucositis Download PDF

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Publication number
CN108904720A
CN108904720A CN201811037695.5A CN201811037695A CN108904720A CN 108904720 A CN108904720 A CN 108904720A CN 201811037695 A CN201811037695 A CN 201811037695A CN 108904720 A CN108904720 A CN 108904720A
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parts
radix
drug
sunset abelmoschus
vitamin
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徐娟
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Shandong Institute of Cancer Prevention and Treatment
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Shandong Institute of Cancer Prevention and Treatment
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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Abstract

The invention discloses a kind of drugs of therapeutic radiation portacaval mucositis, drug is made of reed root, sunset abelmoschus flower, fungicide, peppermint extracting solution, radix paeoniae rubra, Radix Rehmanniae, Radix Ophiopogonis, honeysuckle, Prunella vulgaris, dendrobium nobile, Radix Glycyrrhizae, rhizoma nelumbinis, pure water, Radix Astragali, kuh-seng, Radix Isatidis, the coptis, cordate houttuynia, lily and vitamin, and the group of parts by weight is divided into:15~25 parts of reed root;6~15 parts of sunset abelmoschus flower.Drug of the invention is made of reed root, sunset abelmoschus flower, fungicide, peppermint extracting solution, radix paeoniae rubra, Radix Rehmanniae, Radix Ophiopogonis, honeysuckle, Prunella vulgaris, dendrobium nobile, Radix Glycyrrhizae, rhizoma nelumbinis, pure water, Radix Astragali, kuh-seng, Radix Isatidis, the coptis, cordate houttuynia, lily and vitamin, pure Chinese medicine formula, it is suitable for that various people use, fungicide can kill intraoral harmful bacteria simultaneously, to improve the therapeutic effect of this drug, and peppermint extracting solution can make faint scent of this drug with peppermint, keep entrance nice and cool, improves the comfort level of people's medication.

Description

A kind of drug of therapeutic radiation portacaval mucositis
Technical field
The present invention relates to technical field of pharmaceuticals, specially a kind of drug of therapeutic radiation portacaval mucositis.
Background technique
Portacaval mucositis is exactly canker sore, also known as " aphtha ", and the disease is most to be occurred between 20 years old to 50 years old, morbidity When mostly with constipation, halitosis phenomena such as, which is when people are infected in restrovirus i.e. body, to ensconce caused by virus infection Subepidermal blood vessel, and bred in nucleus, when body immune system exception, these viruses can especially active, the state of an illness Can obviously it deteriorate, expert thinks, canker sore also belongs to a kind of " modern civilization diseases ", because being in over fatigue there are many patient Fall ill afterwards, in addition, canker sore be recognized as it is related with factors such as heredity, hormone, such as canker sore meeting before feminine menstrual There is deterioration situation, climacteric women case, which has, increases phenomenon, but then disease incidence is lower by period of pregnancy women, these phenomenons, which are all shown, bursts The generation of ulcer is influenced by hormone variation, and the drug of existing treatment portacaval mucositis all contains western medicine composition, leads to pregnant woman et al. Group should not take, and drug itself is more bitter, and children taking can generate very big resentment, for this purpose, it is proposed that a kind for the treatment of The drug of radioactivity portacaval mucositis.
Summary of the invention
The purpose of the present invention is to provide a kind of drugs of therapeutic radiation portacaval mucositis, to solve above-mentioned background technique The problem of middle proposition.
To achieve the above object, the present invention provides the following technical solutions:A kind of drug of therapeutic radiation portacaval mucositis, Drug by reed root, sunset abelmoschus flower, fungicide, peppermint extracting solution, radix paeoniae rubra, Radix Rehmanniae, Radix Ophiopogonis, honeysuckle, Prunella vulgaris, dendrobium nobile, Radix Glycyrrhizae, Rhizoma nelumbinis, pure water, Radix Astragali, kuh-seng, Radix Isatidis, the coptis, cordate houttuynia, lily and vitamin composition, the group of parts by weight are divided into: 15~25 parts of reed root;6~15 parts of sunset abelmoschus flower;5~15 parts of fungicide;6~15 parts of peppermint extracting solution;10~20 parts of radix paeoniae rubra;It is raw 15~25 parts of ground;8~16 parts of Radix Ophiopogonis;15~30 parts of honeysuckle;8~16 parts of Prunella vulgaris;8~20 parts of dendrobium nobile;3~15 parts of Radix Glycyrrhizae; 10~20 parts of rhizoma nelumbinis;200~400 parts of pure water;3~10 parts of Radix Astragali;5~8 parts of kuh-seng;4~10 parts of Radix Isatidis;The coptis 4~8 Part;4~10 parts of cordate houttuynia;2~6 parts of lily;5~10 parts of vitamin.
Preferably, the sunset abelmoschus flower is by sunset abelmoschus flower seed meal, sunset abelmoschus flower pollen, maniod ebish flower extract and yellow another name for Sichuan Province Sunflower root powder composition, the group of parts by weight are divided into:12~18 parts of sunset abelmoschus flower seed meal;22~28 parts of sunset abelmoschus flower pollen; 45~50 parts of maniod ebish flower extract;10~15 parts of sunset abelmoschus flower root powder.
Preferably, the fungicide is selected from the derivative of ethyl alcohol, isopropanol, methyl p-hydroxybenzoate and para hydroxybenzene first Acetoacetic ester, butyl p-hydroxybenzoate, propylparaben derivative, hydrogen peroxide, urea peroxide derivative and Other fungicide, and other fungicide are selected from Chlorhexidine, chlorhexidine gluconate, pyrisept, triclosan Or one of sodium hypochlorite.
Preferably, the peppermint extracting solution is made of base oil, Peppermint essential oil, borneol essential oil and sweet orange oil, weight The group of number is divided into:15~25 parts of base oil;35~45 parts of Peppermint essential oil;25~35 parts of borneol essential oil;Sweet orange oil 10~20 Part.
Preferably, the vitamin is in vitamin C, vitamin E, vitamin B1, vitamin B2 or vitamin K A kind of or any two or more mixture.
Preferably, preparation method includes the following steps:
A, by reed root, sunset abelmoschus flower, radix paeoniae rubra, Radix Rehmanniae, Radix Ophiopogonis, honeysuckle, Prunella vulgaris, dendrobium nobile, Radix Glycyrrhizae, rhizoma nelumbinis, Radix Astragali, kuh-seng, Radix Isatidis, the coptis, cordate houttuynia and lily are dried for use after cleaning out;
B, reed root, sunset abelmoschus flower, radix paeoniae rubra, Radix Rehmanniae, Radix Ophiopogonis, honeysuckle, Prunella vulgaris, dendrobium nobile, Radix Glycyrrhizae, lotus root are weighed by formula rate Section, Radix Astragali, kuh-seng, Radix Isatidis, the coptis, cordate houttuynia and lily, and weighed raw material is put into trash extraction box after removal impurity It is put into togerther in drying box and carries out drying and processing, and drying temperature is 60~80 DEG C, drying time is 1~1.5h;
C, the raw material after drying is subjected to pulverization process;
D, smashed mixture is screened by the sieve of 80 molybdenums, and underproof raw material is reapposed over pulverizer Interior carry out separating twice, until its qualification;
E, qualified raw material will be crushed to be put into decoction pot, first impregnates 30~45min with pure water, then boiled, and boil 20~30min is heated with 50~70 DEG C of constant temperatures afterwards;
F, after the completion of continuous heating, the fungicide of formula rate, peppermint extracting solution and vitamin are added in decoction pot, and even 10~15min of continuous stirring, finally cooled and filtered at normal temperature;
G, homogeneous deployed medicament is input in ultrahigh-temperature instant sterilizer, and the temperature control of ultrahigh-temperature instant sterilizer Between 130~150 DEG C, between 0.75~0.85MPa, the time controls between 2~4s Steam pressure control;
H, medicament is poured into flask for medicinal preparations in sterile environment after sterilizing and is sealed in time.
Compared with prior art, beneficial effects of the present invention are as follows:
Drug of the invention is withered by reed root, sunset abelmoschus flower, fungicide, peppermint extracting solution, radix paeoniae rubra, Radix Rehmanniae, Radix Ophiopogonis, honeysuckle, summer Grass, dendrobium nobile, Radix Glycyrrhizae, rhizoma nelumbinis, pure water, Radix Astragali, kuh-seng, Radix Isatidis, the coptis, cordate houttuynia, lily and vitamin composition, pure Chinese medicine Formula is suitable for that various people use, while fungicide can kill intraoral harmful bacteria, to improve controlling for this drug Therapeutic effect, and peppermint extracting solution can make this drug have the faint scent of peppermint, keep entrance nice and cool, improve the comfort level of people's medication.
Detailed description of the invention
Fig. 1 is ingredient table schematic diagram of the present invention.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
Referring to Fig. 1, a kind of drug of therapeutic radiation portacaval mucositis, drug by reed root, sunset abelmoschus flower, fungicide, Peppermint extracting solution, radix paeoniae rubra, Radix Rehmanniae, Radix Ophiopogonis, honeysuckle, Prunella vulgaris, dendrobium nobile, Radix Glycyrrhizae, rhizoma nelumbinis, pure water, Radix Astragali, kuh-seng, plate are blue Root, the coptis, cordate houttuynia, lily and vitamin composition, the group of parts by weight are divided into:15~25 parts of reed root;Sunset abelmoschus flower 6~15 Part;5~15 parts of fungicide;6~15 parts of peppermint extracting solution;10~20 parts of radix paeoniae rubra;15~25 parts of Radix Rehmanniae;8~16 parts of Radix Ophiopogonis;Gold and silver Spend 15~30 parts;8~16 parts of Prunella vulgaris;8~20 parts of dendrobium nobile;3~15 parts of Radix Glycyrrhizae;10~20 parts of rhizoma nelumbinis;Pure water 200~400 Part;3~10 parts of Radix Astragali;5~8 parts of kuh-seng;4~10 parts of Radix Isatidis;4~8 parts of the coptis;4~10 parts of cordate houttuynia;2~6 parts of lily; 5~10 parts of vitamin, pure Chinese medicine formula is suitable for that various people use, while fungicide can carry out intraoral harmful bacteria It kills, to improve the therapeutic effect of this drug, and peppermint extracting solution can make this drug have the faint scent of peppermint, keep entrance nice and cool, Improve the comfort level of people's medication.
Sunset abelmoschus flower is by sunset abelmoschus flower seed meal, sunset abelmoschus flower pollen, maniod ebish flower extract and sunset abelmoschus flower root powder group At the group of parts by weight is divided into:12~18 parts of sunset abelmoschus flower seed meal;22~28 parts of sunset abelmoschus flower pollen;Sunset abelmoschus flower mentions Take 45~50 parts of object;10~15 parts of sunset abelmoschus flower root powder.
Fungicide is selected from the derivative of ethyl alcohol, isopropanol, methyl p-hydroxybenzoate and ethyl-para-hydroxybenzoate, to hydroxyl The derivative of yl benzoic acid butyl ester, propylparaben, the derivative and other fungicide of hydrogen peroxide, urea peroxide, And other fungicide are in Chlorhexidine, chlorhexidine gluconate, pyrisept, triclosan or sodium hypochlorite One kind.
Peppermint extracting solution is made of base oil, Peppermint essential oil, borneol essential oil and sweet orange oil, the component of parts by weight For:15~25 parts of base oil;35~45 parts of Peppermint essential oil;25~35 parts of borneol essential oil;10~20 parts of sweet orange oil.
Vitamin is selected from one of vitamin C, vitamin E, vitamin B1, vitamin B2 or vitamin K or arbitrarily Two or more mixtures.
Preparation method includes the following steps:
A, by reed root, sunset abelmoschus flower, radix paeoniae rubra, Radix Rehmanniae, Radix Ophiopogonis, honeysuckle, Prunella vulgaris, dendrobium nobile, Radix Glycyrrhizae, rhizoma nelumbinis, Radix Astragali, kuh-seng, Radix Isatidis, the coptis, cordate houttuynia and lily are dried for use after cleaning out;
B, reed root, sunset abelmoschus flower, radix paeoniae rubra, Radix Rehmanniae, Radix Ophiopogonis, honeysuckle, Prunella vulgaris, dendrobium nobile, Radix Glycyrrhizae, lotus root are weighed by formula rate Section, Radix Astragali, kuh-seng, Radix Isatidis, the coptis, cordate houttuynia and lily, and weighed raw material is put into trash extraction box after removal impurity It is put into togerther in drying box and carries out drying and processing, and drying temperature is 60~80 DEG C, drying time is 1~1.5h;
C, the raw material after drying is subjected to pulverization process;
D, smashed mixture is screened by the sieve of 80 molybdenums, and underproof raw material is reapposed over pulverizer Interior carry out separating twice, until its qualification;
E, qualified raw material will be crushed to be put into decoction pot, first impregnates 30~45min with pure water, then boiled, and boil 20~30min is heated with 50~70 DEG C of constant temperatures afterwards;
F, after the completion of continuous heating, the fungicide of formula rate, peppermint extracting solution and vitamin are added in decoction pot, and even 10~15min of continuous stirring, finally cooled and filtered at normal temperature;
G, homogeneous deployed medicament is input in ultrahigh-temperature instant sterilizer, and the temperature control of ultrahigh-temperature instant sterilizer Between 130~150 DEG C, between 0.75~0.85MPa, the time controls between 2~4s Steam pressure control;
H, medicament is poured into flask for medicinal preparations in sterile environment after sterilizing and is sealed in time.
In use, withered by reed root, sunset abelmoschus flower, fungicide, peppermint extracting solution, radix paeoniae rubra, Radix Rehmanniae, Radix Ophiopogonis, honeysuckle, summer Grass, dendrobium nobile, Radix Glycyrrhizae, rhizoma nelumbinis, pure water, Radix Astragali, kuh-seng, Radix Isatidis, the coptis, cordate houttuynia, lily and vitamin composition, pure Chinese medicine Formula is suitable for that various people use, while fungicide can kill intraoral harmful bacteria, to improve controlling for this drug Therapeutic effect, and peppermint extracting solution can make this drug have the faint scent of peppermint, keep entrance nice and cool, improve the comfort level of people's medication.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding And modification, the scope of the present invention is defined by the appended.

Claims (6)

1. a kind of drug of therapeutic radiation portacaval mucositis, it is characterised in that:Drug is by reed root, sunset abelmoschus flower, fungicide, thin Lotus extracting solution, radix paeoniae rubra, Radix Rehmanniae, Radix Ophiopogonis, honeysuckle, Prunella vulgaris, dendrobium nobile, Radix Glycyrrhizae, rhizoma nelumbinis, pure water, Radix Astragali, kuh-seng, Radix Isatidis, The coptis, cordate houttuynia, lily and vitamin composition, the group of parts by weight are divided into:15~25 parts of reed root;6~15 parts of sunset abelmoschus flower; 5~15 parts of fungicide;6~15 parts of peppermint extracting solution;10~20 parts of radix paeoniae rubra;15~25 parts of Radix Rehmanniae;8~16 parts of Radix Ophiopogonis;Honeysuckle 15~30 parts;8~16 parts of Prunella vulgaris;8~20 parts of dendrobium nobile;3~15 parts of Radix Glycyrrhizae;10~20 parts of rhizoma nelumbinis;200~400 parts of pure water; 3~10 parts of Radix Astragali;5~8 parts of kuh-seng;4~10 parts of Radix Isatidis;4~8 parts of the coptis;4~10 parts of cordate houttuynia;2~6 parts of lily;Dimension life 5~10 parts of element.
2. a kind of drug of therapeutic radiation portacaval mucositis according to claim 1, it is characterised in that:The sunset abelmoschus root Flower is made of sunset abelmoschus flower seed meal, sunset abelmoschus flower pollen, maniod ebish flower extract and sunset abelmoschus flower root powder, parts by weight Group is divided into:12~18 parts of sunset abelmoschus flower seed meal;22~28 parts of sunset abelmoschus flower pollen;45~50 parts of maniod ebish flower extract;It is yellow 10~15 parts of Althaea roseal root powder.
3. a kind of drug of therapeutic radiation portacaval mucositis according to claim 1, it is characterised in that:The fungicide Derivative selected from ethyl alcohol, isopropanol, methyl p-hydroxybenzoate and ethyl-para-hydroxybenzoate, butyl p-hydroxybenzoate, The derivative of propylparaben, the derivative and other fungicide of hydrogen peroxide, urea peroxide, and other fungicide select From one of Chlorhexidine, chlorhexidine gluconate, pyrisept, triclosan or sodium hypochlorite.
4. a kind of drug of therapeutic radiation portacaval mucositis according to claim 1, it is characterised in that:The peppermint mentions Liquid is taken to be made of base oil, Peppermint essential oil, borneol essential oil and sweet orange oil, the group of parts by weight is divided into:Base oil 15~25 Part;35~45 parts of Peppermint essential oil;25~35 parts of borneol essential oil;10~20 parts of sweet orange oil.
5. a kind of drug of therapeutic radiation portacaval mucositis according to claim 1, it is characterised in that:The vitamin Selected from one of vitamin C, vitamin E, vitamin B1, vitamin B2 or vitamin K or any two or more mixing Object.
6. a kind of drug of therapeutic radiation portacaval mucositis according to any one of claims 1 to 5, it is characterised in that: Preparation method includes the following steps:
A, by reed root, sunset abelmoschus flower, radix paeoniae rubra, Radix Rehmanniae, Radix Ophiopogonis, honeysuckle, Prunella vulgaris, dendrobium nobile, Radix Glycyrrhizae, rhizoma nelumbinis, Radix Astragali, kuh-seng, Radix Isatidis, the coptis, cordate houttuynia and lily are dried for use after cleaning out;
B, reed root, sunset abelmoschus flower, radix paeoniae rubra, Radix Rehmanniae, Radix Ophiopogonis, honeysuckle, Prunella vulgaris, dendrobium nobile, Radix Glycyrrhizae, lotus root are weighed by formula rate Section, Radix Astragali, kuh-seng, Radix Isatidis, the coptis, cordate houttuynia and lily, and weighed raw material is put into trash extraction box after removal impurity It is put into togerther in drying box and carries out drying and processing, and drying temperature is 60~80 DEG C, drying time is 1~1.5h;
C, the raw material after drying is subjected to pulverization process;
D, smashed mixture is screened by the sieve of 80 molybdenums, and underproof raw material is reapposed over pulverizer Interior carry out separating twice, until its qualification;
E, qualified raw material will be crushed to be put into decoction pot, first impregnates 30~45min with pure water, then boiled, and boil 20~30min is heated with 50~70 DEG C of constant temperatures afterwards;
F, after the completion of continuous heating, the fungicide of formula rate, peppermint extracting solution and vitamin are added in decoction pot, and even 10~15min of continuous stirring, finally cooled and filtered at normal temperature;
G, homogeneous deployed medicament is input in ultrahigh-temperature instant sterilizer, and the temperature control of ultrahigh-temperature instant sterilizer Between 130~150 DEG C, between 0.75~0.85MPa, the time controls between 2~4s Steam pressure control;
H, medicament is poured into flask for medicinal preparations in sterile environment after sterilizing and is sealed in time.
CN201811037695.5A 2018-09-06 2018-09-06 A kind of drug of therapeutic radiation portacaval mucositis Pending CN108904720A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110151713A (en) * 2019-05-22 2019-08-23 苏州知时生物科技有限公司 Plant oral mucosa fibrosis chewable tablets and preparation method thereof
CN113559234A (en) * 2021-09-01 2021-10-29 四川省医学科学院·四川省人民医院 Traditional Chinese medicine for preventing and treating mucositis and using method thereof

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