CN108904707A - A kind of antibacterial type eyedrops and its configuration method - Google Patents
A kind of antibacterial type eyedrops and its configuration method Download PDFInfo
- Publication number
- CN108904707A CN108904707A CN201810955672.6A CN201810955672A CN108904707A CN 108904707 A CN108904707 A CN 108904707A CN 201810955672 A CN201810955672 A CN 201810955672A CN 108904707 A CN108904707 A CN 108904707A
- Authority
- CN
- China
- Prior art keywords
- parts
- antibacterial type
- seaear
- shell
- eyedrops
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003889 eye drop Substances 0.000 title claims abstract description 43
- 229940012356 eye drops Drugs 0.000 title claims abstract description 43
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 40
- 238000000034 method Methods 0.000 title claims description 8
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 24
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 24
- 241001145025 Saussurea involucrata Species 0.000 claims abstract description 24
- 229940116229 borneol Drugs 0.000 claims abstract description 24
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 24
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 24
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims abstract description 21
- 241000205585 Aquilegia canadensis Species 0.000 claims abstract description 21
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims abstract description 21
- 241000026010 Dendrobium candidum Species 0.000 claims abstract description 21
- 235000011201 Ginkgo Nutrition 0.000 claims abstract description 21
- 235000008100 Ginkgo biloba Nutrition 0.000 claims abstract description 21
- 229940037003 alum Drugs 0.000 claims abstract description 21
- 235000012907 honey Nutrition 0.000 claims abstract description 21
- 229940041616 menthol Drugs 0.000 claims abstract description 21
- 239000000843 powder Substances 0.000 claims abstract description 21
- 244000062995 Cassia occidentalis Species 0.000 claims abstract description 20
- 235000001948 Cassia occidentalis Nutrition 0.000 claims abstract description 20
- 241000207199 Citrus Species 0.000 claims abstract description 17
- 235000020971 citrus fruits Nutrition 0.000 claims abstract description 17
- 241000218628 Ginkgo Species 0.000 claims description 20
- 239000012530 fluid Substances 0.000 claims description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 239000002893 slag Substances 0.000 claims description 10
- 241000510032 Ellipsaria lineolata Species 0.000 claims description 9
- 239000012153 distilled water Substances 0.000 claims description 7
- 238000009835 boiling Methods 0.000 claims description 5
- 239000000706 filtrate Substances 0.000 claims description 5
- 239000002994 raw material Substances 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 claims description 2
- 238000012856 packing Methods 0.000 claims description 2
- 230000001954 sterilising effect Effects 0.000 claims description 2
- 238000009461 vacuum packaging Methods 0.000 claims description 2
- 244000025254 Cannabis sativa Species 0.000 claims 1
- 244000037364 Cinnamomum aromaticum Species 0.000 claims 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims 1
- 244000131316 Panax pseudoginseng Species 0.000 claims 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims 1
- 235000003140 Panax quinquefolius Nutrition 0.000 claims 1
- 235000008434 ginseng Nutrition 0.000 claims 1
- 239000008188 pellet Substances 0.000 claims 1
- 241000411851 herbal medicine Species 0.000 abstract description 6
- 239000002253 acid Substances 0.000 abstract description 5
- DCKVNWZUADLDEH-UHFFFAOYSA-N sec-butyl acetate Chemical compound CCC(C)OC(C)=O DCKVNWZUADLDEH-UHFFFAOYSA-N 0.000 abstract description 5
- 239000000150 Sympathomimetic Substances 0.000 abstract description 3
- 230000003213 activating effect Effects 0.000 abstract description 3
- 229930013930 alkaloid Natural products 0.000 abstract description 3
- 150000003797 alkaloid derivatives Chemical class 0.000 abstract description 3
- 150000001413 amino acids Chemical class 0.000 abstract description 3
- 230000036772 blood pressure Effects 0.000 abstract description 3
- 239000002158 endotoxin Substances 0.000 abstract description 3
- 230000004438 eyesight Effects 0.000 abstract description 3
- 210000005036 nerve Anatomy 0.000 abstract description 3
- 230000001151 other effect Effects 0.000 abstract description 3
- 230000036407 pain Effects 0.000 abstract description 3
- 102000004169 proteins and genes Human genes 0.000 abstract description 3
- 108090000623 proteins and genes Proteins 0.000 abstract description 3
- 230000008961 swelling Effects 0.000 abstract description 3
- 230000001975 sympathomimetic effect Effects 0.000 abstract description 3
- 208000035859 Drug effect increased Diseases 0.000 abstract description 2
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 abstract description 2
- 229930003944 flavone Natural products 0.000 abstract description 2
- -1 flavone compound Chemical class 0.000 abstract description 2
- 235000011949 flavones Nutrition 0.000 abstract description 2
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 abstract description 2
- 244000194101 Ginkgo biloba Species 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 8
- 229940079593 drug Drugs 0.000 description 5
- 241000675108 Citrus tangerina Species 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 208000030533 eye disease Diseases 0.000 description 4
- 208000002177 Cataract Diseases 0.000 description 3
- 230000003115 biocidal effect Effects 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 2
- 208000034700 Vitreous opacities Diseases 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- HUAXVMFURHMMNJ-UHFFFAOYSA-N 6-[(2,3-dioxo-1h-indol-6-yl)oxy]-1h-indole-2,3-dione Chemical compound C1=C2C(=O)C(=O)NC2=CC(OC=2C=C3NC(C(C3=CC=2)=O)=O)=C1 HUAXVMFURHMMNJ-UHFFFAOYSA-N 0.000 description 1
- 206010010741 Conjunctivitis Diseases 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 241001111421 Pannus Species 0.000 description 1
- 208000017442 Retinal disease Diseases 0.000 description 1
- 206010038923 Retinopathy Diseases 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 238000011221 initial treatment Methods 0.000 description 1
- 208000023343 iris disease Diseases 0.000 description 1
- 206010023332 keratitis Diseases 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 210000003786 sclera Anatomy 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/285—Aucklandia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8984—Dendrobium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Insects & Arthropods (AREA)
- Marine Sciences & Fisheries (AREA)
- Animal Husbandry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of antibacterial type eyedrops, the formula of the antibacterial type eyedrops is as follows：It calculates by ratio of weight and the number of copies：1-3.5 parts of saussurea involucrata, 2-5 parts of the shell of seaear, 3-10 parts of Cassia occidentalis, 2-10 parts of dendrobium candidum, 5-20 parts of butterfly alum, 4-10 parts of borneol, 6-20 parts of cortex magnoliae officinalis, 2-15 parts of Radix Glycyrrhizae, 10-20 parts of honey, Citrus reticuiata Blano 3-5 parts of river, male 5-10 parts of ginkgo leaf, 2-20 parts of honeysuckle, 2-10 parts of Radix Salviae Miltiorrhizae, 8-12 parts of pearl powder, 6-15 parts of menthol.Saussurea involucrata contains protein, amino acid, flavone compound, alkaloid etc., with clearing and activating the channels and collaterals, hemostasia and detumescence, isostere endotoxin and other effects, the shell of seaear plays the role of heat-clearing, calmness, blood pressure lowering, sympathomimetic nerve, borneol dissipates stagnated fire, goes screen improving eyesight, swelling and pain relieving, sorb acid butyl ester has bactericidal effect, sorb acid butyl ester is used cooperatively with Chinese herbal medicine formula, can be activated the effective component of Chinese herbal medicine itself, be substantially increased drug effect.
Description
Technical field
The invention belongs to eyedrops technical fields, more specifically more particularly to a kind of antibacterial type eyedrops.Meanwhile this
Invention further relates to a kind of configuration method of antibacterial type eyedrops.
Background technique
Eye disease is divided into inside and outside barrier eye disease, such as keratitis, pannus, conjunctivitis, sclera, iris disease by TCM Ophthalmology, i.e.,
Visually visible person claims external opculopathy eye disease, and intraocular illness need to claim cataracta ophthalmopathy by instrument examiner, as cataract, vitreous opacity,
Retinopathy etc..The eyedrops (cream) sold on the market now, although very much, primary treatment effect is substantially with anti-inflammatory
Based on, also only to inflammation, though have in these drugs as " fog-removing medicine " treats vitreous opacity, the treatment such as " C16H8N2O5 " cataract
Equal cataracta ophthalmopathies.Theoretically truly have basis, it should effectively, but it is clinically not all right.Cataracta ophthalmopathy cannot not only be treated,
It is just to maintain and does not develop, do not deteriorate and be also unable to handle.In addition to antibiotic is with regard to few other effective medicines in drug for diminishing inflammation and antibiosis
Object.The drug resistance of antibiotic is well-known.
In addition to a small number of Chinese materia medica preparations, remaining is Western medicine.In addition commercially available medicament for the eyes cost is excessively high, increases the burden of patient,
And it is ineffective.For most of the elderlys, eyes long sight presbyopic even early cataract is very common eye
Disease, what almost everybody was more or less suffers from these diseases, but it is poor to go back eyedrops bactericidal effect on the market now.
For this purpose, it is proposed that a kind of antibacterial type eyedrops and its configuration method improve the bactericidal effect of eyedrops.
Summary of the invention
The purpose of the present invention is to solve disadvantage existing in the prior art, and a kind of antibacterial type eyedrops that proposes and
Its configuration method.
To achieve the above object, the present invention provides the following technical solutions：
The formula of a kind of antibacterial type eyedrops, the antibacterial type eyedrops is as follows：It calculates by ratio of weight and the number of copies：Saussurea involucrata 1-
3.5 parts, 2-5 parts of the shell of seaear, 3-10 parts of Cassia occidentalis, 2-10 parts of dendrobium candidum, 5-20 parts of butterfly alum, 4-10 parts of borneol, cortex magnoliae officinalis 6-
20 parts, 2-15 parts of Radix Glycyrrhizae, 10-20 parts of honey, Citrus reticuiata Blano 3-5 parts of river, male 5-10 parts of ginkgo leaf, 2-20 parts of honeysuckle, Radix Salviae Miltiorrhizae
2-10 parts, 8-12 parts of pearl powder, 6-15 parts of menthol.
Preferably, the formula of the antibacterial type eyedrops is as follows：It calculates by ratio of weight and the number of copies：1 part of saussurea involucrata, 2 parts of the shell of seaear,
3 parts of Cassia occidentalis, 2 parts of dendrobium candidum, 5 parts of butterfly alum, 4 parts of borneol, 6 parts of cortex magnoliae officinalis, 2 parts of Radix Glycyrrhizae, 10 parts of honey, 3 parts of river Citrus reticuiata Blano,
5 parts of male ginkgo leaf, 2 parts of honeysuckle, 2 parts of Radix Salviae Miltiorrhizae, 8 parts of pearl powder, 6 parts of menthol.
Preferably, the formula of the antibacterial type eyedrops is as follows：It calculates by ratio of weight and the number of copies：3.5 parts of saussurea involucrata, the shell of seaear 5
Part, 10 parts of Cassia occidentalis, 10 parts of dendrobium candidum, 20 parts of butterfly alum, 10 parts of borneol, 20 parts of cortex magnoliae officinalis, 15 parts of Radix Glycyrrhizae, 20 parts of honey, river
5 parts of Citrus reticuiata Blano, male 10 parts of ginkgo leaf, 20 parts of honeysuckle, 10 parts of Radix Salviae Miltiorrhizae, 12 parts of pearl powder, 15 parts of menthol.
Preferably, it calculates by ratio of weight and the number of copies：2 parts of saussurea involucrata, 3.5 parts of the shell of seaear, 6 parts of Cassia occidentalis, 5 parts of dendrobium candidum, butterfly
10 parts of butterfly alum, 6 parts of borneol, 10 parts of cortex magnoliae officinalis, 8.5 parts of Radix Glycyrrhizae, 15 parts of honey, 4 parts of river Citrus reticuiata Blano, male 8 parts of ginkgo leaf, honeysuckle
10 parts, 5 parts of Radix Salviae Miltiorrhizae, 9 parts of pearl powder, 9 parts of menthol.
The present invention also provides a kind of configuration methods of antibacterial type eyedrops, it is characterised in that：Include the following steps：
S1, saussurea involucrata, the shell of seaear, Cassia occidentalis, dendrobium candidum, butterfly alum, borneol, cortex magnoliae officinalis, Radix Glycyrrhizae, river red tangerine are weighed by component
Skin, male ginkgo leaf, pearl powder, menthol, Radix Salviae Miltiorrhizae, honeysuckle are clean spare wash with distilled water；
S2, the raw material that S1 is got ready are put into boiling machine, are cooked by slow fire 2-3 hours, are filtered out filtrate, cooled and filtered obtains
Without slag medical fluid；
S3, by S2 complete without honey is added in slag medical fluid, stir evenly；
S4, the medical fluid for completing S3, sterilize；
S5, then the medical fluid completed in S4 is dispensed into eyedrops bottle.
Preferably, the saussurea involucrata in the S1, the shell of seaear, Cassia occidentalis, dendrobium candidum, butterfly alum, borneol, cortex magnoliae officinalis, Radix Glycyrrhizae, bee
Honey, river Citrus reticuiata Blano, male ginkgo leaf, pearl powder, borneol, menthol, Radix Salviae Miltiorrhizae, honeysuckle after being cleaned up using distilled water,
It needs to carry out ozone respectively or ultraviolet light carries out sterilizing.
Preferably, proposed in the S2 by saussurea involucrata, the shell of seaear, Cassia occidentalis, dendrobium candidum, butterfly alum, borneol, river
When Piao, Radix Glycyrrhizae, honey, river Citrus reticuiata Blano, male ginkgo leaf, pearl powder, menthol, Radix Salviae Miltiorrhizae, honeysuckle are cooked by slow fire, need
Twice plus water, 3000mL water is added every time.
Preferably, the manner of packing mentioned in the S5 is vacuum packaging.
Technical effect and advantage of the invention：Saussurea involucrata contains protein, amino acid, flavone compound, alkaloid etc., tool
Have a clearing and activating the channels and collaterals, hemostasia and detumescence, isostere endotoxin and other effects, the shell of seaear have heat-clearing, calmness, blood pressure lowering, sympathomimetic nerve work
With borneol dissipates stagnated fire, goes screen improving eyesight, swelling and pain relieving, and sorb acid butyl ester has bactericidal effect, sorb acid butyl ester and Chinese herbal medicine formula
It is used cooperatively, the effective component of Chinese herbal medicine itself can be activated, substantially increase drug effect.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, below in conjunction with specific embodiment, to this
Invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, not
For limiting the present invention.Based on the embodiments of the present invention, those of ordinary skill in the art are not before making creative work
Every other embodiment obtained is put, shall fall within the protection scope of the present invention.
Embodiment 1
The formula of a kind of antibacterial type eyedrops, the antibacterial type eyedrops is as follows：It calculates by ratio of weight and the number of copies：1 part of saussurea involucrata,
2 parts of the shell of seaear, 3 parts of Cassia occidentalis, 2 parts of dendrobium candidum, 5 parts of butterfly alum, 4 parts of borneol, 6 parts of cortex magnoliae officinalis, 2 parts of Radix Glycyrrhizae, 10 parts of honey, river
3 parts of Citrus reticuiata Blano, male 5 parts of ginkgo leaf, 2 parts of honeysuckle, 2 parts of Radix Salviae Miltiorrhizae, 8 parts of pearl powder, 6 parts of menthol.
A kind of antibacterial type eyedrops of the present invention includes the following steps in configuration：
S1, saussurea involucrata, the shell of seaear, Cassia occidentalis, dendrobium candidum, butterfly alum, borneol, cortex magnoliae officinalis, Radix Glycyrrhizae, river red tangerine are weighed by component
Skin, male ginkgo leaf, pearl powder, menthol, Radix Salviae Miltiorrhizae, honeysuckle are clean spare wash with distilled water；
S2, the raw material that S1 is got ready are put into boiling machine, are cooked by slow fire 2-3 hours, are filtered out filtrate, cooled and filtered obtains
Without slag medical fluid；
S3, by S2 complete without honey is added in slag medical fluid, stir evenly；
S4, the medical fluid for completing S3, sterilize；
S5, then the medical fluid completed in S4 is dispensed into eyedrops bottle.
Embodiment 2
The formula of a kind of antibacterial type eyedrops, the antibacterial type eyedrops is as follows：It calculates by ratio of weight and the number of copies：Saussurea involucrata 3.5
Part, 5 parts of the shell of seaear, 10 parts of Cassia occidentalis, 10 parts of dendrobium candidum, 20 parts of butterfly alum, 10 parts of borneol, 20 parts of cortex magnoliae officinalis, 15 parts of Radix Glycyrrhizae, bee
20 parts of honey, 5 parts of river Citrus reticuiata Blano, male 10 parts of ginkgo leaf, 20 parts of honeysuckle, 10 parts of Radix Salviae Miltiorrhizae, 12 parts of pearl powder, 15 parts of menthol.
A kind of antibacterial type eyedrops of the present invention includes the following steps in configuration：
S1, saussurea involucrata, the shell of seaear, Cassia occidentalis, dendrobium candidum, butterfly alum, borneol, cortex magnoliae officinalis, Radix Glycyrrhizae, river red tangerine are weighed by component
Skin, male ginkgo leaf, pearl powder, menthol, Radix Salviae Miltiorrhizae, honeysuckle are clean spare wash with distilled water；
S2, the raw material that S1 is got ready are put into boiling machine, are cooked by slow fire 2-3 hours, are filtered out filtrate, cooled and filtered obtains
Without slag medical fluid；
S3, by S2 complete without honey is added in slag medical fluid, stir evenly；
S4, the medical fluid for completing S3, sterilize；
S5, then the medical fluid completed in S4 is dispensed into eyedrops bottle.
Embodiment 3
The formula of a kind of antibacterial type eyedrops, the antibacterial type eyedrops is as follows：It calculates by ratio of weight and the number of copies：2 parts of saussurea involucrata,
3.5 parts of the shell of seaear, 6 parts of Cassia occidentalis, 5 parts of dendrobium candidum, 10 parts of butterfly alum, 6 parts of borneol, 10 parts of cortex magnoliae officinalis, 8.5 parts of Radix Glycyrrhizae, honey
15 parts, 4 parts of river Citrus reticuiata Blano, male 8 parts of ginkgo leaf, 10 parts of honeysuckle, 5 parts of Radix Salviae Miltiorrhizae, 9 parts of pearl powder, 9 parts of menthol.
A kind of antibacterial type eyedrops of the present invention includes the following steps in configuration：
S1, saussurea involucrata, the shell of seaear, Cassia occidentalis, dendrobium candidum, butterfly alum, borneol, cortex magnoliae officinalis, Radix Glycyrrhizae, river red tangerine are weighed by component
Skin, male ginkgo leaf, pearl powder, menthol, Radix Salviae Miltiorrhizae, honeysuckle are clean spare wash with distilled water；
S2, the raw material that S1 is got ready are put into boiling machine, are cooked by slow fire 2-3 hours, are filtered out filtrate, cooled and filtered obtains
Without slag medical fluid；
S3, by S2 complete without honey is added in slag medical fluid, stir evenly；
S4, the medical fluid for completing S3, sterilize；
S5, then the medical fluid completed in S4 is dispensed into eyedrops bottle.
Drug ingedient data statistics when 1-3 of the embodiment of the present invention is implemented, obtains following table：
The present invention counts the effect that drug uses when implementing, and obtains following table：
In summary：The statistical observation tried out by 5 days users, according to upper table, it can be concluded that, the present invention actually makes
The average bactericidal rate of used time is between 88%-90%, and the present invention contains protein, amino acid, flavonoid by saussurea involucrata
Object, alkaloid etc., have clearing and activating the channels and collaterals, hemostasia and detumescence, isostere endotoxin and other effects, the shell of seaear have heat-clearing, calmness, blood pressure lowering,
The effect of sympathomimetic nerve, borneol dissipate stagnated fire, go screen improving eyesight, swelling and pain relieving, and sorb acid butyl ester has bactericidal effect, sorbic acid fourth
Ester is used cooperatively with Chinese herbal medicine formula, can be activated the effective component of Chinese herbal medicine itself, be substantially increased drug effect.
Finally it should be noted that：The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention,
Although the present invention is described in detail referring to the foregoing embodiments, for those skilled in the art, still may be used
To modify the technical solutions described in the foregoing embodiments or equivalent replacement of some of the technical features,
All within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on should be included in of the invention
Within protection scope.
Claims (8)
1. a kind of antibacterial type eyedrops, it is characterised in that：The formula of the antibacterial type eyedrops is as follows：It counts by ratio of weight and the number of copies
It calculates：1-3.5 parts of saussurea involucrata, 2-5 parts of the shell of seaear, 3-10 parts of Cassia occidentalis, 2-10 parts of dendrobium candidum, 5-20 parts of butterfly alum, borneol 4-10
Part, 6-20 parts of cortex magnoliae officinalis, 2-15 parts of Radix Glycyrrhizae, 10-20 parts of honey, Citrus reticuiata Blano 3-5 parts of river, male 5-10 parts of ginkgo leaf, honeysuckle 2-
20 parts, 2-10 parts of Radix Salviae Miltiorrhizae, 8-12 parts of pearl powder, 6-15 parts of menthol.
2. a kind of antibacterial type eyedrops according to claim 1, it is characterised in that：The formula of the antibacterial type eyedrops is such as
Under：It calculates by ratio of weight and the number of copies：1 part of saussurea involucrata, 2 parts of the shell of seaear, 3 parts of Cassia occidentalis, 2 parts of dendrobium candidum, 5 parts of butterfly alum, borneol 4
Part, 6 parts of cortex magnoliae officinalis, 2 parts of Radix Glycyrrhizae, 10 parts of honey, 3 parts of river Citrus reticuiata Blano, male 5 parts of ginkgo leaf, 2 parts of honeysuckle, 2 parts of Radix Salviae Miltiorrhizae, pearl
8 parts of powder, 6 parts of menthol.
3. a kind of antibacterial type eyedrops according to claim 1, it is characterised in that：The formula of the antibacterial type eyedrops is such as
Under：It calculates by ratio of weight and the number of copies：3.5 parts of saussurea involucrata, 5 parts of the shell of seaear, 10 parts of Cassia occidentalis, 10 parts of dendrobium candidum, 20 parts of butterfly alum, ice
10 parts of piece, 20 parts of cortex magnoliae officinalis, 15 parts of Radix Glycyrrhizae, 20 parts of honey, 5 parts of river Citrus reticuiata Blano, male 10 parts of ginkgo leaf, 20 parts of honeysuckle, Radix Salviae Miltiorrhizae
10 parts, 12 parts of pearl powder, 15 parts of menthol.
4. a kind of antibacterial type eyedrops according to claim 1, it is characterised in that：The formula of the antibacterial type eyedrops is such as
Under：It calculates by ratio of weight and the number of copies：2 parts of saussurea involucrata, 3.5 parts of the shell of seaear, 6 parts of Cassia occidentalis, 5 parts of dendrobium candidum, 10 parts of butterfly alum, borneol
6 parts, 10 parts of cortex magnoliae officinalis, 8.5 parts of Radix Glycyrrhizae, 15 parts of honey, 4 parts of river Citrus reticuiata Blano, male 8 parts of ginkgo leaf, 10 parts of honeysuckle, 5 parts of Radix Salviae Miltiorrhizae,
9 parts of pearl powder, 9 parts of menthol.
5. a kind of configuration method of antibacterial type eyedrops described in claim 1, it is characterised in that：Include the following steps：
S1, weighed by component saussurea involucrata, the shell of seaear, Cassia occidentalis, dendrobium candidum, butterfly alum, borneol, cortex magnoliae officinalis, Radix Glycyrrhizae, river Citrus reticuiata Blano,
Male ginkgo leaf, pearl powder, menthol, Radix Salviae Miltiorrhizae, honeysuckle are clean spare wash with distilled water；
S2, the raw material that S1 is got ready are put into boiling machine, are cooked by slow fire 2-3 hours, and filtrate is filtered out, and cooled and filtered is obtained without slag
Medical fluid；
S3, by S2 complete without honey is added in slag medical fluid, stir evenly；
S4, the medical fluid for completing S3, sterilize；
S5, then the medical fluid completed in S4 is dispensed into eyedrops bottle.
6. a kind of antibacterial type eyedrops according to claim 5, it is characterised in that：Saussurea involucrata, the shell of seaear in the S1, grass
Cassia, dendrobium candidum, butterfly alum, borneol, cortex magnoliae officinalis, Radix Glycyrrhizae, honey, river Citrus reticuiata Blano, male ginkgo leaf, pearl powder, menthol, pellet
Ginseng, honeysuckle are needed to carry out ozone respectively or ultraviolet light carry out sterilizing after being cleaned up using distilled water.
7. a kind of antibacterial type eyedrops according to claim 5, it is characterised in that：Itd is proposed in the S2 by saussurea involucrata,
The shell of seaear, Cassia occidentalis, dendrobium candidum, butterfly alum, borneol, cortex magnoliae officinalis, Radix Glycyrrhizae, honey, river Citrus reticuiata Blano, male ginkgo leaf, pearl powder,
When menthol, Radix Salviae Miltiorrhizae, honeysuckle are cooked by slow fire, need to add water twice, add 3000mL water every time.
8. a kind of antibacterial type eyedrops according to claim 5, it is characterised in that：The manner of packing mentioned in the S5 is
Vacuum packaging.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810955672.6A CN108904707A (en) | 2018-08-21 | 2018-08-21 | A kind of antibacterial type eyedrops and its configuration method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810955672.6A CN108904707A (en) | 2018-08-21 | 2018-08-21 | A kind of antibacterial type eyedrops and its configuration method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108904707A true CN108904707A (en) | 2018-11-30 |
Family
ID=64405517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810955672.6A Pending CN108904707A (en) | 2018-08-21 | 2018-08-21 | A kind of antibacterial type eyedrops and its configuration method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108904707A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110538275A (en) * | 2019-10-09 | 2019-12-06 | 苏州知时生物科技有限公司 | plant bacteriostatic liquid for field survival and preparation process thereof |
-
2018
- 2018-08-21 CN CN201810955672.6A patent/CN108904707A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110538275A (en) * | 2019-10-09 | 2019-12-06 | 苏州知时生物科技有限公司 | plant bacteriostatic liquid for field survival and preparation process thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103961556A (en) | Dendrobium officinale oculentum for relieving asthenopia | |
| CN103768283A (en) | Traditional Chinese medicine for treating multiple eye diseases | |
| CN105106318B (en) | A kind of Chinese medicine composition and preparation method thereof for treating xerophthalmia | |
| CN108904709A (en) | A kind of pure Chinese medicine eye sticker and the preparation method and application thereof | |
| CN103083546A (en) | Method for processing condensed pill for regaining sight | |
| CN102949523A (en) | Medicinal composition used for relieving visual fatigue and preparation method of capsules thereof | |
| CN105708936A (en) | Traditional Chinese medicinal composition for treating myopia, amblyopia and asthenopia | |
| CN104547621A (en) | Eye protection traditional Chinese medicine | |
| CN108904707A (en) | A kind of antibacterial type eyedrops and its configuration method | |
| CN105560891A (en) | Traditional Chinese medicine eye drops containing borneol and preparation method thereof | |
| CN1160091C (en) | Medicine for treating ophthalmopathy | |
| CN106620278A (en) | Bacteriostatic traditional Chinese medicinal eye drops as well as preparation method and application thereof | |
| CN107519309B (en) | Ophthalmic combination suit | |
| CN103505562B (en) | For treating the Chinese medicine of keratitis | |
| CN105902686A (en) | In-situ gel eyewash containing nano-carbon crystals and preparation method thereof | |
| CN107648397B (en) | Traditional Chinese medicine composition for treating liver-kidney yin deficiency and preparation method and application thereof | |
| CN110269895A (en) | A kind of visual rehabilitation Chinese medicine composition containing fresh Chinese medicine and preparation method thereof, preparation | |
| CN1857531A (en) | Recipe, preparing process and application of Chinese medicine preparation for treating diabetic retinopathy | |
| CN110624086A (en) | Traditional Chinese medicine composition beneficial to improving eyesight and preparation method thereof | |
| CN104173732A (en) | Traditional Chinese medicinal preparation for treating acute conjunctivitis | |
| CN102940753A (en) | Pills for treating glaucoma and preparation method | |
| CN114569643B (en) | Application of carpesium abrotanoides in treating early-stage chalazion | |
| CN106491730A (en) | A kind of treat Chinese medicine composition of glaucoma and preparation method thereof | |
| CN105168589A (en) | Eye-care traditional Chinese medicine gel preparation and preparation method thereof | |
| CN101293056A (en) | Medicament for preventing and treating near-sightedness |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20181130 |