CN108902325A - Compound packet of a kind of baby formula milk powder with prebiotic function and preparation method thereof - Google Patents
Compound packet of a kind of baby formula milk powder with prebiotic function and preparation method thereof Download PDFInfo
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- CN108902325A CN108902325A CN201811034991.XA CN201811034991A CN108902325A CN 108902325 A CN108902325 A CN 108902325A CN 201811034991 A CN201811034991 A CN 201811034991A CN 108902325 A CN108902325 A CN 108902325A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/16—Agglomerating or granulating milk powder; Making instant milk powder; Products obtained thereby
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
- A23C9/156—Flavoured milk preparations ; Addition of fruits, vegetables, sugars, sugar alcohols or sweeteners
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Abstract
The present invention relates to the baby formula milk powders and preparation method thereof that baby formula milk powder field, in particular to a kind of pair of enteron aisle have prebiotic function.In the milk powder, by testing in vivo and in vitro, the mixed proportion of galactooligosaccharide and the compound packet of polydextrose is proposed and demonstrated 4:1 or 9:In 1 range, when the total addition level of preferred oligosaccharide is 5.0 parts by weight/100 parts by weight milk powder, there are obvious probiotic effects to enteron aisle.And taste smell, brew, structural state and the color of babies ' formula milk powder are not adversely affected, but clearly enhance instant capacity.Formula milk of the invention can adjust baby intestinal flora, have the function of relax bowel and defecation and improve immunity of organisms.
Description
Technical field
The present invention relates to the preparations of the compound packet of one kind baby formula milk powder easy to use, with prebiotic function and formula milk
Method, and in particular, to a kind of for adjusting the baby formula milk powder of function of intestinal canal.
Background technique
Cradle is the based periods that intestinal flora is established, even more critical period.Intestinal flora can regard human body as
An organ, there is the growth for inhibiting pathogenic bacteria, prevent disease, improve the functions such as immunity of organisms, therefore in baby
Period is extremely important to the adjusting of intestinal flora balance.The baby for feeding breast milk, since dietary fiber can stimulate in breast milk
The growth of beneficial bacteria simultaneously inhibits harmful bacteria to be proliferated, so as to so that cradle intestinal flora reaches balance.But nowadays human milk
Feeding rate declines year by year, and newborn is caused to need to make up the missing of breast milk dietary fiber as far as possible by baby food.It is double
Discrimination bacillus and lactobacillus acidophilus are the very important bacterium of infant's intestinal flora, and number of the two in enteron aisle is evaluation machine
The important indicator of body health degree such as adheres to Human Epithelial Cells because they have good healthcare function, promotes lactose resistance to
By property and digestion etc., but both how to make simultaneously Effective multiplication be researcher's problems faced.
Currently, usually add the proliferation that some prebiotics realize beneficial bacteriums, generally include galactooligosaccharide, polydextrose,
Oligoisomaltose, xylo-oligosaccharide, oligofructose etc. are common, but how which prebiotics or which kind of prebiotics compound meeting needle
Effective multiplication and symbiosis is cooperateed with to still belong to blank at present simultaneously Bifidobacterium and lactobacillus acidophilus.
Galactooligosaccharide is mainly applied in formula milk, acidified milk and milk beverage etc. in food.In formula milk pink collar
Domain, galactooligosaccharide are mainly used in babies ' formula milk powder or Milk powder for middle-aged and old people.The baby of artificial feeding and breast-feeding
Baby intestinal flora is widely different, and the phenomenon that be also often accompanied with constipation, and adds the dietary fibers such as galactooligosaccharide
Babies ' formula milk powder can be very good to prevent this phenomenon.Galactooligosaccharide can not only improve digestive function, can also generate
Vitamin B makes the food nutrition of addition galactooligosaccharide more abundant, and making to add the baby food of galactooligosaccharide not only can be with
Female composition of milk is simulated, can be promoted health with various aspects.But galactooligosaccharide is individually added, due to its strong moisturizing
Property, it will usually so that the caking property during milk-powder brewing increases, influence milk powder instant capacity.
Polydextrose is also common one of dietary fiber type, and polydextrose is the product polymerizeing at random, glycosidic bond kind
Class is more, and molecular structure is complicated, can increase the growth and breeding of body beneficial bacterium, all obtained in food service industry at home and abroad compared with
For wide application, applied in the dairy products such as baby formula milk powder or special medical food also relatively extensively.Polydextrose tool
The common features for thering are other dietary fibers to have, such as：The growth for promoting the probiotics such as Bifidobacterium, lactic acid bacteria in enteron aisle, maintains
Intestinal flora balance；Improve function of intestinal canal, reduce the generation of enteron aisle corrupt substance, relief of constipation prevents diarrhea；It is anti-to reduce glucemia
It should wait.Polydextrose is a kind of dietary fiber slowly to ferment, soluble easily in water.
Although the prebiotics such as above-mentioned galactooligosaccharide, polydextrose, oligoisomaltose, xylo-oligosaccharide, oligofructose exist
It is widely used in babies ' formula milk powder, but is independent addition or mixing addition is respectively played a role or act on simple folds
Add, there is no the mutual collaboration played between prebiotics component, the effect to bring out the best in each other；And during preparing milk powder,
Addition is weighed and mixed together with other raw materials, it is inconvenient.
Therefore, develop the dietary fiber of a kind of specific components and proportion the compound packet of prebiotics have to preparation it is significant prebiotic
The baby formula milk powder of function more has practical significance.
Summary of the invention
An object of the present invention is to provide the prebiotic of baby formula milk powder of a kind of pair of enteron aisle with prebiotic function
The compound packet of member and its compound a kind of standby baby formula milk powder is packed with this.
The second object of the present invention is to by research babies ' formula milk powder in dietary fiber to Bifidobacterium and acidophilus cream bar
The influence of bacterium viable count and different dietary fibers are demonstrated in babies ' formula milk powder to the measurement of mouse function of relaxing bowel
Additive amount is to the opposite sex of significance difference existing for the prebiotic function effect of enteron aisle.
The present invention provides the baby formula milk powders that a kind of pair of enteron aisle has prebiotic function, and the milk powder product is by following
Parts by weight at being grouped as：
Basic milk powder 100-200 parts, 3-15 parts of prebiotics compound packet；It is preferred that basic 100 parts of milk powder：Compound 5 parts of packet；By low
Poly- galactolipin and polydextrose press 4:1 or 9:1 ratio combination.
The preparation method of milk powder of the present invention, includes the following steps：
Babies ' formula milk powder preparation flow：Raw material milk checks and accepts → cream → cooling, storage → ingredient (addition minerals, heat only
Stable vitamin, vegetable oil etc.) (it is multiple that prebiotics are added in → homogeneous → cooling → sterilization, concentration → spray drying → ry blend ingredients
Close packet and thermally labile vitamin etc.) → packaging → product inspection
(a) raw milk checks and accepts items as defined in the quality standard GB19301-2010 for having to comply with national Fresh Milk purchase
It is required that strictly carrying out organoleptic examination, physicochemical property inspection and Micro biological Tests.Cream cannot be processed immediately when need to store one section
Between, it is necessary to 4-6 DEG C are cooled to through cooler after purification, is stored squeezing into storage tank.
(b) it should be required in proportion when ingredient, various materials are mixed in pill tank, blender is started, mix material.
(c) mixture homogenization pressure general control is in 18MPa.
(d) method for using high-temperature instantaneous sterilization can not only be such that microorganism almost all in cream kills, can also make in cream
Protein reaches soft clot, is easier to digest and assimilate after eating.
(e) it is concentrated in vacuo a quarter for requiring raw milk to be concentrated into original volume, milk dry matter reaches 45% or so.Concentration
Newborn temperature control system afterwards is at 47-50 DEG C.
(f) after the emulsion droplet formed by spraying is dry under ideal drying condition, diameter can be reduced to the 75% of initial emulsion droplet,
Weight is reduced to 50%, and volume is about reduced to 50%.
(g) dietary fiber and some thermal instability vitamins needs are added after spray drying.
(h) dry milk powder falls into the bottom of hothouse, and powder temperature is 60 DEG C or so, should go out powder as early as possible.
It can also be prepared by the other conventional methods in this field.
Beneficial effect：
Currently, usually add the proliferation that some prebiotics realize beneficial bacteriums, generally include galactooligosaccharide, polydextrose,
Oligoisomaltose, xylo-oligosaccharide, oligofructose etc. are common.But how which prebiotics or which kind of prebiotics, which compound, to make
Bifidobacterium and lactobacillus acidophilus Effective multiplication and symbiosis is cooperateed with to still belong to blank current.Applicant is in extensive work early period
On the basis of, it is creative that galactooligosaccharide and polydextrose are pressed 4:1 or 9:1 is prepared by mixing into compound packet for formula milk
Preparation, can effectively adjust baby intestinal flora so that Bifidobacterium and lactobacillus acidophilus be compared to being used only one of which,
Two kinds of bacterium numbers dramatically increase, generate collaboration symbiosis effect, while inhibit harmful bacteria be proliferated effect reach most preferably, so as to so that
Cradle intestinal flora reaches balance.Prebiotics can promote growth of probiotics, and prebiotics have the facilitation of probiotics
Certain selectivity, different prebiotics are used in combination down the present invention at a specific ratio, to the probiotic effects of enteron aisle
It can be obviously improved, 1+1 can be reached>2 effect.Internal in vitro test shows to produce to be difficult to expect technical effect.
In addition, galactooligosaccharide is individually added, due to its strong moisture retention, so that the caking property during milk-powder brewing increases
Add, influence milk powder instant capacity, in this regard, discovery is shared with polydextrose and can be solved the above problems, polydextrose is soluble easily in water and is
A kind of dietary fiber slowly to ferment, is used in combination with the dietary fiber that galactooligosaccharide quickly and completely ferments, and can slow down
The fermentation rate of total dietary fiber declines with making pH milder, and the less stimulation of this protection baby's enteral layer and anal region improves
The tolerance of baby, it is most important that while Bifidobacterium and lactobacillus acidophilus Effective multiplication can also be made and cooperate with symbiosis
Effect, possible this is related to polydextrose complicated molecule structure.
Provide a kind of formula milk of specific proportion given efficacy of specific composition.
Specific embodiment
1 a kind of pair of enteron aisle of embodiment has the baby formula milk powder of prebiotic function,
The milk powder product matched as follows is formed after being added to the compound package of prebiotics point in milk powder：Prebiotics it is compound packet by
The galactooligosaccharide and polydextrose of amount described in table 1 form.
1 formula milk constituent of table
Wherein, (every 100 parts) formulas of the formula of basic milk powder are as follows：
Experiment one：The compound package pairing number of live bacteria of probiotics of dietary fiber influences in babies ' formula milk powder
Experimental method：
Experimental example 1：Using the baby formula milk powder of embodiment 1 as culture medium, by Bifidobacterium and lactobacillus acidophilus point
It is not inoculated into milk powder culture medium, 37 DEG C of Anaerobic culturels are diluted coated plate after for 24 hours, and it is laggard to grow bacterium colony by 37 DEG C of culture 48h
Row bacterium colony counts.
Control group 1：Using the milk powder of embodiment 1 as culture medium, compound packet is not added, and parts by weight can be replaced with physiological saline
Generation.
Control group 2：Using the milk powder of embodiment 1 as culture medium, compound packet is only the galactooligosaccharide of equivalent.
Control group 3：Using the milk powder of embodiment 1 as culture medium, compound packet is only the polydextrose of equivalent.
Control group 4：Using the milk powder of embodiment 1 as culture medium, compound packet be only the galactooligosaccharide of equivalent, polydextrose and
Oligofructose, three's proportion are 1:1:1.
Experimental result is shown in Table 2：
The compound package pairing number of live bacteria of probiotics of dietary fiber influences in 2 milk powder of table
Table 2 the result shows that, the addition of oligosaccharide can promote the growth of Bifidobacterium and lactobacillus acidophilus, while be added to benefit
The control group for only adding a kind of prebiotics is apparently higher than to the facilitation effect of probiotics after the raw compound packet of member.In addition, in compound packet
Three kinds of prebiotics are added compared with the compound packet for only adding two kinds of prebiotics, 2 kinds are slightly better than 3 kinds, this more shows oligomeric gala
The remarkable effect that sugar, polydextrose cooperate.
Experiment two：Dietary fiber influences mouse intestinal flora in babies ' formula milk powder
Experimental method：Mouse is randomly divided into 5 groups, 5 groups of mouse feed grade equivalent milk powder, continuous gavage 14d, detection daily
The bacterium number of Bifidobacterium and lactobacillus acidophilus in mouse intestinal excrement.Experimental group is the formulated infant milk of stomach-filling mouse embodiment 1
Powder, control group 1 can be physiological saline.Control group 2-4 ditto tests the setting of the 2-4 in one, the results are shown in Table 3
Dietary fiber influences mouse intestinal flora in 3 babies ' formula milk powder of table
Experiment three：Dietary fiber influences mouse bowel relaxing functions in babies ' formula milk powder
Animal packet and nursing：
Mouse is divided into two batches, first is used for the measurement of Small intestine advance activity, and second batch is used for the measurement of defecation.Every batch of
7 groups are randomly divided into, every group of 7 mouse, by its human intervention at equal extent constipation.Respectively：Low, middle and high dose groups, control
Group 1 (physiological saline group), control group 2-4, wherein the compound packet additive amount of the daily stomach-filling mouse dietary fiber of low, middle and high dose groups
Respectively 1 parts by weight/100 parts by weight, 3 parts by weight/100 parts by weight, 5 parts by weight/100 parts by weight milk powder；1 stomach-filling of control group
Physiological saline, control group 2-4 ditto test control group 2-4 in one set and the compound packet additive amount of stomach-filling dietary fiber as 5 weights
Measure part/100 parts by weight milk powder.Above-mentioned daily normal grade equivalent stomach-filling, continuous gavage 14d；Every group of measurement result is made even
Mean value.
The Small intestine advance activity of mouse, the defecation time of mouse, defecation grain number and stool weight are all made of this field routine
Method measurement.
Experimental result see the table below：
During test, the excrement shape of mouse is normal, without the generation of constipation, diarrhea and other ill symptoms, says
The bright babies ' formula milk powder containing galactooligosaccharide and polydextrose does not have undesirable influence to mouse growth.
The influence of Table A difference dietary fiber additive amount and type to mouse small intestine advancing movement
By Table A it is found that after giving the compound packet babies ' formula milk powder 14d of mouse difference dietary fiber, ink progradation exists
Significant difference.The ink progradation of middle and high dosage group mouse is significantly increased compared with model group, is illustrated galactooligosaccharide and is gathered
Glucose can promote when additive amount is 3 parts by weight/100 parts by weight and 5 parts by weight/100 parts by weight in babies ' formula milk powder
The intestines peristalsis of mouse.And when dietary fiber content is 5 parts by weight/100 parts by weight in babies ' formula milk powder, effect is most
It is good then high then unhelpful.In addition, being apparently higher than only addition one to the facilitation effect of probiotics after being added to the compound packet of prebiotics simultaneously
The control group of kind prebiotics, and three kinds of prebiotics are added in compound packet compared with the compound packet effect for only adding two kinds of prebiotics, 2
Kind is slightly better than 3 kinds.
The influence of table B difference dietary fiber additive amount and type to mouse defecation situation
The influence of different dietary fiber additive amounts and type to mouse defecation as shown in tableb, is added to the compound packet of prebiotics
Afterwards, the function of intestinal canal of mouse is obviously improved.And galactooligosaccharide and polydextrose additive amount are 3 weight in babies ' formula milk powder
When part/100 parts by weight and 5 parts by weight/100 parts by weight, the relax bowel and defecation ability of mouse can be reinforced.Meals in babies ' formula milk powder
Eat fiber content be 5 parts by weight/100 parts by weight when, i.e., high dose group improve mouse relax bowel and defecation ability more preferably, and with middle dose
Amount group is in significant difference, then high then unhelpful.In addition, obvious to the facilitation effect of probiotics after being added to the compound packet of prebiotics simultaneously
Three kinds of prebiotics are added higher than the control group for only adding a kind of prebiotics, and in compound packet and only add the compound of two kinds of prebiotics
Packet effect is compared, and 2 kinds are slightly better than 3 kinds.
It also found by experiment, galactooligosaccharide and polydextrose 4:1 and 9:1 liang of effect is suitable, and other ratio effects are not
Good, the phenomenon and reason needs are continuing to explore from now on.
The foregoing is merely presently preferred embodiments of the present invention, all equivalent changes done according to scope of the present invention patent with
Modification, all should belong to covering scope of the invention.
Claims (5)
1. mixed proportion is 4：1 or 9:1 galactooligosaccharide and the compound packet of polydextrose are being prepared to the raw function of intestinal beneficial
Baby formula milk powder in purposes.
2. mixed proportion is 4：1 or 9:The compound packet of 1 galactooligosaccharide and polydextrose simultaneously to Bifidobacterium in enteron aisle and
Purposes in live lactobacillus acidophilus number Effective multiplication.
3. the compound packet of Bifidobacterium and live lactobacillus acidophilus number Effective multiplication in a kind of pair of enteron aisle, which is characterized in that by low
Poly- galactolipin and polydextrose by weight 4：1 or 9:1 ratio combination.
4. the preparation method that a kind of pair of enteron aisle has the baby formula milk powder of prebiotic function, which is characterized in that by claim
Any one of 1-3 compound packet is formed with basic milk powder, wherein basic milk powder 100-200 parts, compound packet is 3- in terms of mass parts
15 parts；Wherein basic milk powder (every 100 parts by weight) is formulated as follows：
5. the baby formula milk powder that a kind of pair of enteron aisle has prebiotic function, which is characterized in that according to claim 4 the method
Preparation.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811034991.XA CN108902325A (en) | 2018-09-06 | 2018-09-06 | Compound packet of a kind of baby formula milk powder with prebiotic function and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811034991.XA CN108902325A (en) | 2018-09-06 | 2018-09-06 | Compound packet of a kind of baby formula milk powder with prebiotic function and preparation method thereof |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1312685A (en) * | 1998-08-11 | 2001-09-12 | 利尔生公司 | Carbohydrate mixture |
| CN102657262A (en) * | 2005-06-01 | 2012-09-12 | 美赞臣营养品公司 | Use of polydextrose for simulating the functional attributes of human milk oligosaccharides in formula-fed infants |
| CN106605709A (en) * | 2015-10-22 | 2017-05-03 | 内蒙古伊利实业集团股份有限公司 | Liquid milk suitable for children at 3-6 years old and preparation method thereof |
| CN107198250A (en) * | 2017-05-23 | 2017-09-26 | 北京瑞千景科技发展有限公司 | Improve intestinal microecology Chronic disease prevention composition and balanced nutritious food and application |
| CN108142928A (en) * | 2017-12-25 | 2018-06-12 | 北京数果科技有限公司 | For the compound probiotic composition of intestinal canal regulating and its application |
-
2018
- 2018-09-06 CN CN201811034991.XA patent/CN108902325A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1312685A (en) * | 1998-08-11 | 2001-09-12 | 利尔生公司 | Carbohydrate mixture |
| CN102657262A (en) * | 2005-06-01 | 2012-09-12 | 美赞臣营养品公司 | Use of polydextrose for simulating the functional attributes of human milk oligosaccharides in formula-fed infants |
| CN106605709A (en) * | 2015-10-22 | 2017-05-03 | 内蒙古伊利实业集团股份有限公司 | Liquid milk suitable for children at 3-6 years old and preparation method thereof |
| CN107198250A (en) * | 2017-05-23 | 2017-09-26 | 北京瑞千景科技发展有限公司 | Improve intestinal microecology Chronic disease prevention composition and balanced nutritious food and application |
| CN108142928A (en) * | 2017-12-25 | 2018-06-12 | 北京数果科技有限公司 | For the compound probiotic composition of intestinal canal regulating and its application |
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Application publication date: 20181130 |