CN108888678A

CN108888678A - A kind of anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract

Info

Publication number: CN108888678A
Application number: CN201810861137.4A
Authority: CN
Inventors: 江裕业; 张芙蓉
Original assignee: Guangzhou Jiayuan Daily Necessities Co Ltd
Current assignee: Guangzhou Jiayuan Daily Necessities Co Ltd
Priority date: 2018-07-29
Filing date: 2018-07-29
Publication date: 2018-11-27

Abstract

The invention discloses a kind of anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract, the Essence includes:Water, propylene glycol, niacinamide, ethyl alcohol, Bacillus acidi lactici/pear juice tunning, o- cymene -5- alcohol, Cortex Phellodendri extract, white willow bark extract, European pear berry extract, neem leaf extract, radix scutellariae root extract, houttuynia extract, Wild soybean albumen, beta glucan, yeast extract, arginine, acrylic acid（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer, Sodium Polyacrylate, cetearyl methicone, PEG-40 stearate, stereth -2, stereth -21,1,2- hexylene glycol, parahydroxyacet-ophenone, decoyl hydroximic acid, glycerol caprylate.The present invention contains a variety of extracted form natural plant essence, and anti-acne ingredient is made using pure Chinese medicine formula, and containing a variety of anti-oxidant, inhibition TYR enzymes, anti-acne effect is significant, and preparation method is simple.

Description

A kind of anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract

Technical field

The present invention relates to pharmaceutical technology fields, specifically a kind of to extract containing Bacillus acidi lactici, cordate houttuynia and white willow bark The anti-acne essence of object.

Background technique

Acne is a kind of chronic inflammatory skin of pilosebaceous unit, teenager is mainly apt to occur in, to teenager Psychology and social influence it is very big.Clinical manifestation is with the pleomorphism skin lesion such as acne, papule, warts, tubercle for being apt to occur in face Feature, nickname acne, whelk.The generation of acne mainly with hypersteatosis, pilosebaceous duct blocking, bacterium infection It is closely related with the factors such as inflammatory reaction.The level of androgen especially testosterone in descendant's body that adolesces increases rapidly, promotees It is developed into sebaceous glands and generates a large amount of sebums.The dyskeratosis of pilosebaceous duct causes catheter blockage, sebum discharge simultaneously Obstacle forms horn plug, that is, micro mist thorn.Multiple-microorganism especially propionibacterium acnes mass propagation in hair follicle, acne propionic acid bar The lipase that bacterium generates decomposes sebum and generates free fatty acid, while chemotactic inflammatory cell and medium, finally induces and aggravates inflammation Reaction.

The method for the treatment of acne has at present：Oral antibiotic/vitamin/glucocorticoid/sex hormone zinc preparation and external application Drug therapy, the therapies such as injection treatment/laser ultraviolet light in skin lesion.Although these methods also have certain effect, have Certain drawbacks, such as endo-medicine overlong time, the side effects such as antibiotic/hormone, injection treatment/laser ultraviolet light in skin lesion Etc. therapies compare pain, laser therapy easily forms the charring layer of black, interferes surgical field of view, so that patient is not easy observation and grasps treatment The depth reached.If being difficult to the result of control treatment if over the course for the treatment of, assurance is not in place.

The present invention is directed to by research and develop a kind of anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract with The relationship of skin anti-acne maintenance, to seek such skin anti-acne maintenance cosmetics research and development countermeasure.

Bacillus acidi lactici refers to the bacterium that carbohydrate fermentation can be made to generate lactic acid, is that a group is lived in body beneficial to host health Microorganism, it safeguard human health and adjust immune function effect be widely recognized as, lactobacillus genus lactic acid Bacteriaceae, It names, exists extensively, acidophilia because sugar fermentation generates a large amount of lactic acid, existence optimal pH is 5.5 ~ 6.0, certainly, is in PH It still can survive in 3.0 ~ 4.5 environment, it is that acid-resistant strength is strongest in bactacin, has and inhibits pathogen, anti-sense Dye, prevention and the generation for inhibiting tumour enhance immunity of organisms, promote digestion, synthesizing amino acid and vitamin, it is solid to reduce gallbladder Alcohol, inhibits endotoxic production, delays senescence and anti-radiation etc..A host of facts prove, if in skin Bacillus acidi lactici quantity It reduces or loses, flora imbalance occur, it is possible to lead to the generation of certain disease;As long as the quantity of Bacillus acidi lactici increases in skin Add, fauna is balanced, so that it may promote body health and treat certain disease, it is seen then that increase Bacillus acidi lactici in body skin Quantity be to prevent and treat a kind of important measures of certain skin diseases.

The medicinal efficacy of houttuynia extract is very outstanding, houttuynia extract can clearing heat and detoxicating, detumescence treat sore, with controlling reality Heat, heat toxin, damp evil, disease heat etc.；Modern pharmacology experiment shows that houttuynia extract has antibacterial, antiviral, raising immunity of organism The effects of power；The phagocytic activity of WBC can be enhanced in houttuynia extract, improves serum properdin, has to the treatment of infection disease Important meaning；A kind of yellow oil of houttuynia extract, to various microorganisms（Especially saccharomycete and mould）Have Inhibiting effect has apparent inhibiting effect to the streptococcus, staphylococcus aureus, micrococcus catarrhalis of haemolysis；Houttuynia extract There is enhancing immune system effect, improves the phagocytosis of patient's white blood cell；Houttuynia extract has antitumor action, and it is thin to improve cancer CAMP in born of the same parents and inhibit ehrlich ascites cancer；The flavonoids such as Quercetin, quercitrin contained by houttuynia extract and Isoquercitrin Closing object also has significant anti-inflammatory effect, and the significant capillary for inhibiting inflammation early stage of energy is hyperfunction；Houttuynia extract has analgesia, stops Blood inhibits serous secretion, promotes regeneration, and recover from injury the effects of closing the improvement for promoting erythroderma, psoriasis, and cordarine is irritating The effect of skin foaming.

For white willow bark extract as " natural aspirin ", salicoside be used to treat infection, acute and chronic because of hair Pain caused by inflammation.Aspirin (acetylsalicylic acid), as the synthesis substitute of salicoside, as its native configurations, bigcatkin willow Glucoside can harmlessly pass through gastrointestinal system, and salicylic acid is converted into blood and liver, and conversion process needs a few hours, therefore result It will not be arrived immediately by human body sensory, but general effect can last for hours, salicoside is considered as salicis,cortex anti-inflammatory and subtracts The source of light pain ability, the analgesic ability of salicis,cortex usually come into force it is relatively slow but than common aspirin product lasts when Between it is long.

Summary of the invention

Influenced that (such as extraneous physical chemical factor, the variation of autologous hormones level is mechanical in order to solve existing by many factors Pressure, Neuropsychical facto), cause normal skin dysfunction occur, skin collagen textural anomaly becomes fragile, and occurs Related skin damage problem, treatment present in existing treatment product is not thorough, easily repeatedly, side effect is strong, easily forms drug resistance Or effect it is unobvious the defects of, the present invention proposes a kind of anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract Liquid, thorough anti-acne maintenance skin.

Anti-acne maintenance function may be implemented using the composition containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract in the present invention Can problem, also show that anti-acne maintenance function problem quite or even more preferably therapeutic effect.

A kind of anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract, the anti-acne essence contain Water, propylene glycol, niacinamide, ethyl alcohol, Bacillus acidi lactici/pear juice tunning, o- cymene -5- alcohol, Cortex Phellodendri extract, white willow Bark extract, European pear berry extract, neem leaf extract, radix scutellariae root extract, houttuynia extract, Wild soybean egg White, beta glucan, yeast extract, arginine, acrylic acid（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer, poly- third Olefin(e) acid sodium, cetearyl methicone, PEG-40 stearate, stereth -2, stereth -21,1, 2- hexylene glycol, parahydroxyacet-ophenone, decoyl hydroximic acid, glycerol caprylate composition, the composition include it is following by weight The component that percentage calculates:Water 69.45%wt ~ 82.4%wt, propylene glycol 7.0%wt ~ 12.0%wt, niacinamide 3.0%wt ~ 4.0% Wt, ethyl alcohol 2.0%wt ~ 4.0%wt, Bacillus acidi lactici/pear juice tunning 0.2%wt ~ 0.4%wt, o- cymene -5- alcohol 0.1%wt ~ 0.3%wt, Cortex Phellodendri extract 0.3%wt ~ 0.6%wt, white willow（SALIX ALBA）Bark extract 0.5%wt ~ 0.7% Wt, European pear berry extract 0.3%wt ~ 0.6%wt, neem leaf extract 0.3%wt ~ 0.6%wt, radix scutellariae root extract 0.4%wt ~ 0.7%wt, houttuynia extract 0.3%wt ~ 0.6%wt, Wild soybean albumen 0.3%wt ~ 0.6%wt, beta glucan 0.6% Wt ~ 1.2%wt, yeast extract 0.6%wt ~ 1.1%wt, arginine 0.2%wt ~ 0.5%wt, acrylic acid（Ester）Class/C10-30 alkane The poly- methyl silicon of alcohol acrylate crosspolymers 0.3%wt ~ 0.5%wt, Sodium Polyacrylate 0.1%wt ~ 0.15%wt, cetearyl It is oxygen alkane 0.1%wt ~ 0.2%wt, PEG-40 stearate 0.1%wt ~ 0.2%wt, -2 0.1%wt of stereth ~ 0.2%wt, hard - 21 0.1%wt of lipidol polyethers ~ 0.2%wt, 1,2- hexylene glycol 0.25%wt ~ 0.35%wt, parahydroxyacet-ophenone 0.25%wt ~ 0.35%wt, decoyl hydroximic acid 0.1%wt ~ 0.3%wt, glycerol caprylate 0.1%wt ~ 0.3%wt.

A kind of anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract, the anti-acne essence combination Object contain water 69.45%wt ~ 82.4%wt, propylene glycol 7.0%wt ~ 12.0%wt, niacinamide 3.0%wt ~ 4.0%wt, ethyl alcohol 2.0%wt ~ 4.0%wt, Bacillus acidi lactici/pear juice tunning 0.2%wt ~ 0.4%wt, o- cymene -5- alcohol 0.1%wt ~ 0.3%wt, cork tree tree Bark extract 0.3%wt ~ 0.6%wt, white willow bark extract 0.5%wt ~ 0.7%wt, European pear berry extract 0.3%wt ~ 0.6%wt, neem leaf extract 0.3%wt ~ 0.6%wt, radix scutellariae root extract 0.4%wt ~ 0.7%wt, houttuynia extract 0.3%wt ~ 0.6%wt, Wild soybean albumen 0.3%wt ~ 0.6%wt, beta glucan 0.6%wt ~ 1.2%wt, yeast extract 0.6%wt ~ 1.1%wt, arginine 0.2%wt ~ 0.5%wt, acrylic acid（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.3%wt ~ 0.5%wt, Sodium Polyacrylate 0.1%wt ~ 0.15%wt, cetearyl methicone 0.1%wt ~ 0.2%wt, PEG-40 Stearate 0.1%wt ~ 0.2%wt, -2 0.1%wt of stereth ~ 0.2%wt, -21 0.1%wt of stereth ~ 0.2%wt, 1,2- hexylene glycol 0.25%wt ~ 0.35%wt, parahydroxyacet-ophenone 0.25%wt ~ 0.35%wt, decoyl hydroximic acid 0.1%wt ~ 0.3% Wt, glycerol caprylate 0.1%wt ~ 0.3%wt.

A kind of anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract, the anti-acne essence combination Object contains water 72.27%wt ~ 78.94%wt, propylene glycol 8.0%wt ~ 11.0%wt, niacinamide 3.2%wt ~ 3.8%wt, ethyl alcohol 2.5% Wt ~ 3.5%wt, Bacillus acidi lactici/pear juice tunning 0.2%wt ~ 0.3%wt, o- cymene -5- alcohol 0.2%wt ~ 0.3%wt, Huang Bark of a cork tree bark extract 0.4%wt ~ 0.5%wt, white willow bark extract 0.6%wt ~ 0.7%wt, European pear berry extract 0.4%wt ~ 0.6%wt, neem leaf extract 0.4%wt ~ 0.5%wt, radix scutellariae root extract 0.5%wt ~ 0.6%wt, houttuynia extract 0.4%wt ~ 0.5%wt, Wild soybean albumen 0.4%wt ~ 0.5%wt, beta glucan 0.8%wt ~ 1.0%wt, yeast extract 0.8%wt ~ 1.0%wt, arginine 0.3%wt ~ 0.4%wt, acrylic acid（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.4%wt ~ 0.5%wt, Sodium Polyacrylate 0.12%wt ~ 0.15%wt, cetearyl methicone 0.12%wt ~ 0.18%wt, PEG- 40 stearate 0.12%wt ~ 0.18%wt, -2 0.12%wt of stereth ~ 0.16%wt, -21 0.12%wt of stereth ~ 0.16%wt, 1,2- hexylene glycol 0.28%wt ~ 0.32%wt, parahydroxyacet-ophenone 0.28%wt ~ 0.32%wt, decoyl hydroximic acid 0.2%wt ~ 0.28%wt, glycerol caprylate 0.2%wt ~ 0.28%wt.

A kind of anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract, the anti-acne essence combination Object contains water 76.06%wt, propylene glycol 9.0%wt, niacinamide 3.5%wt, ethyl alcohol 3.0%wt, Bacillus acidi lactici/pear juice tunning 0.3%wt, o- cymene -5- alcohol 0.2%wt, Cortex Phellodendri extract 0.5%wt, white willow bark extract 0.6%wt, the West The operatic circle extract 0.5%wt, neem leaf extract 0.5%wt, radix scutellariae root extract 0.5%wt, houttuynia extract 0.4% Wt, Wild soybean albumen 0.4%wt, beta glucan 1.0%wt, yeast extract 0.9%wt, arginine 0.3%wt, acrylic acid（Ester） Class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.4%wt, Sodium Polyacrylate 0.12%wt, cetearyl methyl polysilicone Alkane 0.15%wt, PEG-40 stearate 0.16%wt, -2 0.16%wt of stereth, -21 0.15%wt of stereth, 1,2- hexylene glycol 0.30%wt, parahydroxyacet-ophenone 0.30%wt, decoyl hydroximic acid 0.2%wt, glycerol caprylate 0.2%wt.

A kind of anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract, the water 69.45%wt ~ Reaction kettle is added in 82.4%wt, propylene glycol 7.0%wt ~ 12.0%wt, niacinamide 3.0%wt ~ 4.0%wt, and being then heated to temperature is 95 degrees Celsius；Then acrylic acid is added（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.3%wt ~ 0.5%wt, poly- third Olefin(e) acid sodium 0.1%wt ~ 0.15%wt, cetearyl methicone 0.1%wt ~ 0.2%wt, PEG-40 stearate 0.1%wt ~ 0.2%wt, -2 0.1%wt of stereth ~ 0.2%wt, -21 0.1%wt of stereth ~ 0.2%wt insulated and stirred are to complete Dissolution is subsequently cooled to temperature be 55 degrees Celsius；Ethyl alcohol 2.0%wt ~ 4.0%wt, Bacillus acidi lactici/pear juice tunning is added 0.2%wt ~ 0.4%wt, o- cymene -5- alcohol 0.1%wt ~ 0.3%wt, Cortex Phellodendri extract 0.3%wt ~ 0.6%wt, white willow Bark extract 0.5%wt ~ 0.7%wt, European pear berry extract 0.3%wt ~ 0.6%wt, neem leaf extract 0.3%wt ~ 0.6% Wt, radix scutellariae root extract 0.4%wt ~ 0.7%wt, houttuynia extract 0.3%wt ~ 0.6%wt, Wild soybean albumen 0.3%wt ~ 0.6% Wt, beta glucan 0.6%wt ~ 1.2%wt, yeast extract 0.6%wt ~ 1.1%wt, arginine 0.2%wt ~ 0.5%wt, 1,2- oneself two Alcohol 0.25%wt ~ 0.35%wt, parahydroxyacet-ophenone 0.25%wt ~ 0.35%wt, decoyl hydroximic acid 0.1%wt ~ 0.3%wt, glycerol Caprylate 0.1%wt ~ 0.3%wt is stirred to being completely dissolved, and being cooled to temperature is 40 degrees Celsius, detection discharging.

One or more embodiments according to the present invention, the final ph of the anti-acne essence composition liquid, 2.8-8.2, for example, it is preferable to which pH value is 4.5-7.5, alternatively, such as preferable ph is 4.6-7.2.

One or more embodiments according to the present invention, the water, propylene glycol, niacinamide, ethyl alcohol, Bacillus acidi lactici/pears Juice tunning, o- cymene -5- alcohol, Cortex Phellodendri extract, white willow bark extract, European pear berry extract, azadirachta Leaf extract, radix scutellariae root extract, houttuynia extract, Wild soybean albumen, beta glucan, yeast extract, arginine, propylene Acid（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer, Sodium Polyacrylate, cetearyl methicone, PEG-40 stearate, stereth -2, stereth -21,1,2- hexylene glycol, parahydroxyacet-ophenone, decoyl hydroxyl oxime Acid, glycerol caprylate can be conventional purchase from the market.

One or more embodiments according to the present invention give combination according to the present invention to subject in need Object, the composition are by water, propylene glycol, niacinamide, ethyl alcohol, Bacillus acidi lactici/pear juice tunning, o- cymene -5- alcohol, Huang Bark of a cork tree bark extract, white willow bark extract, European pear berry extract, neem leaf extract, radix scutellariae root extract, cordate houttuynia Extract, Wild soybean albumen, beta glucan, yeast extract, arginine, acrylic acid（Ester）Class/C10-30 alkylol acrylamide acid esters It is cross-linked polymer, Sodium Polyacrylate, cetearyl methicone, PEG-40 stearate, stereth -2, hard Lipidol polyethers -21,1,2- hexylene glycol, parahydroxyacet-ophenone, decoyl hydroximic acid, glycerol caprylate composition.

One or more embodiments according to the present invention, the water, propylene glycol, niacinamide, ethyl alcohol, Bacillus acidi lactici/pears Juice tunning, o- cymene -5- alcohol, Cortex Phellodendri extract, white willow bark extract, European pear berry extract, azadirachta Leaf extract, radix scutellariae root extract, houttuynia extract, Wild soybean albumen, beta glucan, yeast extract, arginine, propylene Acid（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer, Sodium Polyacrylate, cetearyl methicone, PEG-40 stearate, stereth -2, stereth -21,1,2- hexylene glycol, parahydroxyacet-ophenone, decoyl hydroxyl oxime Acid, glycerol caprylate can be and be mixed in composition.

Plant extracts group for anti-acne maintenance function of the present invention containing above-mentioned composition of plant extracts The drug percutaneous skin irritant test of conjunction（Repeatedly）And Skin allergy test, test result are respectively：Skin irritatin intensity point Grade belongs to nonirritant；By sensitization strength grading standard, it is judged to have no skin allergic reaction.

The invention reside in the combination of the plant extracts of anti-acne maintenance, the use in conjunction of each ingredient generates each component effect Synergistic effect, so that making the function of the composition anti-acne maintenance is enhanced, achievees the purpose that anti-acne maintenance with low dosage, and prevent Itch and allergy in skin anti-acne repair process are stopped.

It is not added with glucocorticoid substance and antibiotic in formula of the invention, uses no dependence for a long time, does not have Toxic side effect.

The present invention can not only generate good anti-acne maintenance function in relatively low-dose, but also not have when used for a long time continuously There is the generation of allergic stimulated symptom.Anti-acne maintenance from many aspects makes the corium of anti-acne maintenance by promoting fibroblastic proliferation Cell restarts the metabolism of damaged zone cell and the synthesis of collagen and elastin laminin, and anti-acne maintenance promotes skin healing.

Specific embodiment

It is illustrated to make the objectives, technical solutions, and advantages of the present invention clearer, it is With reference to embodiment, right The present invention is further described.

A kind of preparation method of the anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract includes following step Suddenly：

1. reaction is added in water 69.45%wt ~ 82.4%wt, propylene glycol 7.0%wt ~ 12.0%wt, niacinamide 3.0%wt ~ 4.0%wt Kettle, being then heated to temperature is 95 degrees Celsius.

2. acrylic acid is then added（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.3%wt ~ 0.5%wt is gathered Sodium acrylate 0.1%wt ~ 0.15%wt, cetearyl methicone 0.1%wt ~ 0.2%wt, PEG-40 stearate 0.1%wt ~ 0.2%wt, -2 0.1%wt of stereth ~ 0.2%wt, -21 0.1%wt of stereth ~ 0.2%wt insulated and stirred To complete fat melting, being subsequently cooled to temperature is 55 degrees Celsius.

3. again respectively by ethyl alcohol 2.0%wt ~ 4.0%wt, Bacillus acidi lactici/pear juice tunning 0.2%wt ~ 0.4%wt, o- umbrella Flower hydrocarbon -5- alcohol 0.1%wt ~ 0.3%wt, Cortex Phellodendri extract 0.3%wt ~ 0.6%wt, white willow bark extract 0.5%wt ~ 0.7%wt, European pear berry extract 0.3%wt ~ 0.6%wt, neem leaf extract 0.3%wt ~ 0.6%wt, radix scutellariae root extract 0.4%wt ~ 0.7%wt, houttuynia extract 0.3%wt ~ 0.6%wt, Wild soybean albumen 0.3%wt ~ 0.6%wt, beta glucan 0.6% Wt ~ 1.2%wt, yeast extract 0.6%wt ~ 1.1%wt, arginine 0.2%wt ~ 0.5%wt, 1,2- hexylene glycol 0.25%wt ~ 0.35%wt, parahydroxyacet-ophenone 0.25%wt ~ 0.35%wt, decoyl hydroximic acid 0.1%wt ~ 0.3%wt, glycerol caprylate 0.1%wt ~ 0.3%wt is added reaction kettle and stirs to being completely dissolved, and being cooled to temperature is 40 degrees Celsius, detection discharging.

Following embodiment is illustrated so that anti-acne repairs the composition of skin barrier as an example, but not limited to this, above-mentioned hair The product of the various anti-acne maintenances comprising Bacillus acidi lactici, cordate houttuynia and white willow bark extract of bright proposition is suitable for this hair It is bright.

Embodiment 1：A kind of preparation method of the anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract.

Water 69.45%wt ~ 82.4%wt, propylene glycol 7.0%wt ~ 12.0%wt, niacinamide 3.0%wt ~ 4.0%wt are added anti- Kettle is answered, being then heated to temperature is 95 degrees Celsius；Then acrylic acid is added（Ester）Class/C10-30 alkylol acrylamide acid esters crosslinking is poly- Close object 0.3%wt ~ 0.5%wt, Sodium Polyacrylate 0.1%wt ~ 0.15%wt, cetearyl methicone 0.1%wt ~ 0.2% Wt, PEG-40 stearate 0.1%wt ~ 0.2%wt, -2 0.1%wt of stereth ~ 0.2%wt, stereth -21 0.1% Wt ~ 0.2%wt insulated and stirred is subsequently cooled to temperature be 55 degrees Celsius to being completely dissolved；Addition ethyl alcohol 2.0%wt ~ 4.0%wt, Bacillus acidi lactici/pear juice tunning 0.2%wt ~ 0.4%wt, o- cymene -5- alcohol 0.1%wt ~ 0.3%wt, Cortex Phellodendri extract 0.3%wt ~ 0.6%wt, white willow bark extract 0.5%wt ~ 0.7%wt, European pear berry extract 0.3%wt ~ 0.6%wt, India Chinaberry leaf extract 0.3%wt ~ 0.6%wt, radix scutellariae root extract 0.4%wt ~ 0.7%wt, houttuynia extract 0.3%wt ~ 0.6%wt, Wild soybean albumen 0.3%wt ~ 0.6%wt, beta glucan 0.6%wt ~ 1.2%wt, yeast extract 0.6%wt ~ 1.1%wt, arginine 0.2%wt ~ 0.5%wt, 1,2- hexylene glycol 0.25%wt ~ 0.35%wt, parahydroxyacet-ophenone 0.25%wt ~ 0.35%wt, decoyl hydroxyl Oxime acid 0.1%wt ~ 0.3%wt, glycerol caprylate 0.1%wt ~ 0.3%wt are stirred to being completely dissolved, and being cooled to temperature is 40 degrees Celsius, Detection discharging is to get anti-acne maintenance Essence.

Embodiment 2：A kind of preparation method of the anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract.

Reaction kettle is added in water 76.06%wt, propylene glycol 9.0%wt, niacinamide 3.5%wt, being then heated to temperature is 95 Degree Celsius；Then acrylic acid is added（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.4%wt, Sodium Polyacrylate 0.12%wt, cetearyl methicone 0.15%wt, PEG-40 stearate 0.16%wt, stereth -2 0.16%wt, -21 0.15%wt insulated and stirred of stereth are subsequently cooled to temperature be 55 degrees Celsius to being completely dissolved；Add Enter ethyl alcohol 3.0%wt, Bacillus acidi lactici/pear juice tunning 0.3%wt, o- cymene -5- alcohol 0.2%wt, Cortex Phellodendri extract 0.5%wt, white willow bark extract 0.6%wt, European pear berry extract 0.5%wt, neem leaf extract 0.5%wt, radix scutellariae Root extract 0.5%wt, houttuynia extract 0.4%wt, Wild soybean albumen 0.4%wt, beta glucan 1.0%wt, yeast extract 0.9%wt, arginine 0.3%wt, 1,2- hexylene glycol 0.30%wt, parahydroxyacet-ophenone 0.30%wt, decoyl hydroximic acid 0.2%wt, Glycerol caprylate 0.2%wt is stirred to being completely dissolved, and being cooled to temperature is 40 degrees Celsius, and detection discharging is to get anti-acne maintenance essence Liquid.

Anti-acne maintenance Essence anti-acne repair process：

The conditioning phase：The 1-5 days, skin surface was dry, take off skin, is red, swelling, itching, papule gradually disappears.

During The Withdrawal Period：5th ~ 8 day, 1 week or more is extended to individually, and it is existing that most users will appear giving up of differing in weight As, show as it is red, swell, itch, papule etc..

The reparation phase：9th day ~ the 12nd day, the skin symptom of During The Withdrawal Period（It is red, swollen etc.）Gradually fading, the main table of skin appearance Now for it is dry, take off skin, be red, swelling, itching, papule moves closer to normally, skin condition is unstable, and withrawal symptom easily occurs repeatedly.

Convalescence：12nd day ~ the 16th day, skin appearance and function were almost restored normally, and skin condition has had larger mention It rises, but this is only to seem, it should be noted that consolidate.

It collects 60 scytitis volunteers and participates in test, smear 3 times, 8 days as a treatment course, paid a return visit after 4 courses for the treatment of daily And record recurrence.

Curative effect determinate standard：

It cures：It is dry, take off skin, be red, swelling, itching, the symptoms such as papule disappear；

Effectively：Above-mentioned symptom is alleviated；

In vain：Symptom is unchanged.

Statistical result after every course for the treatment of is shown in Table 1.

Table 1：Statistical result after every course for the treatment of

	After one course for the treatment of	After two courses for the treatment of	After three courses for the treatment of	After four courses for the treatment of
					It cures（Example）	0	23	36	55
Effectively（Example）	58	58	59	59
					In vain（Example）	2	2	1	1
Total effective rate（%）	96	96	98	98

As it can be seen that after using a kind of one course for the treatment of of anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract, skin Symptom has clear improvement, it was demonstrated that the anti-acne maintenance Essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract has significant Reparation skin barrier function.

The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention, therefore All contents without departing from technical solution of the present invention any are simply repaired to what the above implementation was done according to the technical essence of the invention Change, equivalent variations and modification, all of which are still within the scope of the technical scheme of the invention.

Claims

1. a kind of anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract, which is characterized in that the anti-acne essence Magnificent liquid contains water, propylene glycol, niacinamide, ethyl alcohol, Bacillus acidi lactici/pear juice tunning, o- cymene -5- alcohol, Cortex Phellodendri and mentions Take object, white willow bark extract, European pear berry extract, neem leaf extract, radix scutellariae root extract, houttuynia extract, Wild soybean albumen, beta glucan, yeast extract, arginine, acrylic acid（Ester）Class/C10-30 alkylol acrylamide acid esters crosslinking is poly- It is poly- to close object, Sodium Polyacrylate, cetearyl methicone, PEG-40 stearate, stereth -2, stearyl alcohol Ether -21,1,2- hexylene glycol, parahydroxyacet-ophenone, decoyl hydroximic acid, glycerol caprylate composition, the composition include with Under component count by weight percentage:Water 69.45%wt ~ 82.4%wt, propylene glycol 7.0%wt ~ 12.0%wt, niacinamide 3.0% Wt ~ 4.0%wt, ethyl alcohol 2.0%wt ~ 4.0%wt, Bacillus acidi lactici/pear juice tunning 0.2%wt ~ 0.4%wt, o- cymene -5- alcohol 0.1%wt ~ 0.3%wt, Cortex Phellodendri extract 0.3%wt ~ 0.6%wt, white willow bark extract 0.5%wt ~ 0.7%wt, the West The operatic circle extract 0.3%wt ~ 0.6%wt, neem leaf extract 0.3%wt ~ 0.6%wt, radix scutellariae root extract 0.4%wt ~ 0.7%wt, houttuynia extract 0.3%wt ~ 0.6%wt, Wild soybean albumen 0.3%wt ~ 0.6%wt, beta glucan 0.6%wt ~ 1.2% Wt, yeast extract 0.6%wt ~ 1.1%wt, arginine 0.2%wt ~ 0.5%wt, acrylic acid（Ester）Class/C10-30 alkylol acrylamide acid Ester cross-linked polymer 0.3%wt ~ 0.5%wt, Sodium Polyacrylate 0.1%wt ~ 0.15%wt, cetearyl methicone 0.1%wt ~ 0.2%wt, PEG-40 stearate 0.1%wt ~ 0.2%wt, -2 0.1%wt of stereth ~ 0.2%wt, stearyl alcohol - 21 0.1%wt of polyethers ~ 0.2%wt, 1,2- hexylene glycol 0.25%wt ~ 0.35%wt, parahydroxyacet-ophenone 0.25%wt ~ 0.35% Wt, decoyl hydroximic acid 0.1%wt ~ 0.3%wt, glycerol caprylate 0.1%wt ~ 0.3%wt.

2. a kind of anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract according to claim 1, It is characterized in that, the anti-acne essence composition contains water 69.45%wt ~ 82.4%wt, propylene glycol 7.0%wt ~ 12.0%wt, cigarette Amide 3.0%wt ~ 4.0%wt, ethyl alcohol 2.0%wt ~ 4.0%wt, Bacillus acidi lactici/pear juice tunning 0.2%wt ~ 0.4%wt, o- umbrella Flower hydrocarbon -5- alcohol 0.1%wt ~ 0.3%wt, Cortex Phellodendri extract 0.3%wt ~ 0.6%wt, white willow bark extract 0.5%wt ~ 0.7%wt, European pear berry extract 0.3%wt ~ 0.6%wt, neem leaf extract 0.3%wt ~ 0.6%wt, radix scutellariae root extract 0.4%wt ~ 0.7%wt, houttuynia extract 0.3%wt ~ 0.6%wt, Wild soybean albumen 0.3%wt ~ 0.6%wt, beta glucan 0.6% Wt ~ 1.2%wt, yeast extract 0.6%wt ~ 1.1%wt, arginine 0.2%wt ~ 0.5%wt, acrylic acid（Ester）Class/C10-30 alkane The poly- methyl silicon of alcohol acrylate crosspolymers 0.3%wt ~ 0.5%wt, Sodium Polyacrylate 0.1%wt ~ 0.15%wt, cetearyl It is oxygen alkane 0.1%wt ~ 0.2%wt, PEG-40 stearate 0.1%wt ~ 0.2%wt, -2 0.1%wt of stereth ~ 0.2%wt, hard - 21 0.1%wt of lipidol polyethers ~ 0.2%wt, 1,2- hexylene glycol 0.25%wt ~ 0.35%wt, parahydroxyacet-ophenone 0.25%wt ~ 0.35%wt, decoyl hydroximic acid 0.1%wt ~ 0.3%wt, glycerol caprylate 0.1%wt ~ 0.3%wt.

3. a kind of anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract according to claim 1, It is characterized in that, the anti-acne essence composition contains water 72.27%wt ~ 78.94%wt, propylene glycol 8.0%wt ~ 11.0%wt, cigarette Amide 3.2%wt ~ 3.8%wt, ethyl alcohol 2.5%wt ~ 3.5%wt, Bacillus acidi lactici/pear juice tunning 0.2%wt ~ 0.3%wt, o- umbrella Flower hydrocarbon -5- alcohol 0.2%wt ~ 0.3%wt, Cortex Phellodendri extract 0.4%wt ~ 0.5%wt, white willow bark extract 0.6%wt ~ 0.7%wt, European pear berry extract 0.4%wt ~ 0.6%wt, neem leaf extract 0.4%wt ~ 0.5%wt, radix scutellariae root extract 0.5%wt ~ 0.6%wt, houttuynia extract 0.4%wt ~ 0.5%wt, Wild soybean albumen 0.4%wt ~ 0.5%wt, beta glucan 0.8% Wt ~ 1.0%wt, yeast extract 0.8%wt ~ 1.0%wt, arginine 0.3%wt ~ 0.4%wt, acrylic acid（Ester）Class/C10-30 alkane Alcohol acrylate crosspolymers 0.4%wt ~ 0.5%wt, Sodium Polyacrylate 0.12%wt ~ 0.15%wt, the poly- methyl of cetearyl Siloxanes 0.12%wt ~ 0.18%wt, PEG-40 stearate 0.12%wt ~ 0.18%wt, -2 0.12%wt of stereth ~ 0.16%wt, -21 0.12%wt of stereth ~ 0.16%wt, 1,2- hexylene glycol 0.28%wt ~ 0.32%wt, parahydroxyacet-ophenone 0.28%wt ~ 0.32%wt, decoyl hydroximic acid 0.2%wt ~ 0.28%wt, glycerol caprylate 0.2%wt ~ 0.28%wt.

4. a kind of anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract according to claim 1, It is characterized in that, the anti-acne essence composition contains water 76.06%wt, propylene glycol 9.0%wt, niacinamide 3.5%wt, ethyl alcohol 3.0%wt, Bacillus acidi lactici/pear juice tunning 0.3%wt, o- cymene -5- alcohol 0.2%wt, Cortex Phellodendri extract 0.5% Wt, white willow（SALIX ALBA）Bark extract 0.6%wt, European pear berry extract 0.5%wt, neem leaf extract 0.5%wt, radix scutellariae root extract 0.5%wt, houttuynia extract 0.4%wt, Wild soybean albumen 0.4%wt, beta glucan 1.0% Wt, yeast extract 0.9%wt, arginine 0.3%wt, acrylic acid（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.4%wt, Sodium Polyacrylate 0.12%wt, cetearyl methicone 0.15%wt, PEG-40 stearate 0.16% Wt, -2 0.16%wt of stereth, -21 0.15%wt, 1,2- hexylene glycol 0.30%wt of stereth, parahydroxyacet-ophenone 0.30%wt, decoyl hydroximic acid 0.2%wt, glycerol caprylate 0.2%wt.

5. a kind of anti-acne essence containing Bacillus acidi lactici, cordate houttuynia and white willow bark extract according to claim 1, It is characterized in that, the water 69.45%wt ~ 82.4%wt, propylene glycol 7.0%wt ~ 12.0%wt, niacinamide 3.0%wt ~ 4.0%wt add Enter reaction kettle, being then heated to temperature is 95 degrees Celsius；Then acrylic acid is added（Ester）Class/C10-30 alkylol acrylamide acid esters is handed over Linked polymer 0.3%wt ~ 0.5%wt, Sodium Polyacrylate 0.1%wt ~ 0.15%wt, cetearyl methicone 0.1%wt ~ 0.2%wt, PEG-40 stearate 0.1%wt ~ 0.2%wt, -2 0.1%wt of stereth ~ 0.2%wt, stereth -21 0.1%wt ~ 0.2%wt insulated and stirred is subsequently cooled to temperature be 55 degrees Celsius to being completely dissolved；Addition ethyl alcohol 2.0%wt ~ 4.0%wt, Bacillus acidi lactici/pear juice tunning 0.2%wt ~ 0.4%wt, o- cymene -5- alcohol 0.1%wt ~ 0.3%wt, cork tree tree Bark extract 0.3%wt ~ 0.6%wt, white willow bark extract 0.5%wt ~ 0.7%wt, European pear berry extract 0.3%wt ~ 0.6%wt, neem leaf extract 0.3%wt ~ 0.6%wt, radix scutellariae root extract 0.4%wt ~ 0.7%wt, houttuynia extract 0.3%wt ~ 0.6%wt, Wild soybean albumen 0.3%wt ~ 0.6%wt, beta glucan 0.6%wt ~ 1.2%wt, yeast extract 0.6%wt ~ 1.1%wt, arginine 0.2%wt ~ 0.5%wt, 1,2- hexylene glycol 0.25%wt ~ 0.35%wt, parahydroxyacet-ophenone 0.25%wt ~ 0.35%wt, decoyl hydroximic acid 0.1%wt ~ 0.3%wt, glycerol caprylate 0.1%wt ~ 0.3%wt are stirred to being completely dissolved, and are cooled to Temperature is 40 degrees Celsius, detection discharging.