CN108888579A - Composition and bath preparation containing the composition - Google Patents

Composition and bath preparation containing the composition Download PDF

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Publication number
CN108888579A
CN108888579A CN201810620296.5A CN201810620296A CN108888579A CN 108888579 A CN108888579 A CN 108888579A CN 201810620296 A CN201810620296 A CN 201810620296A CN 108888579 A CN108888579 A CN 108888579A
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CN
China
Prior art keywords
bath
composition
following component
preparation
including following
Prior art date
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Granted
Application number
CN201810620296.5A
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Chinese (zh)
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CN108888579B (en
Inventor
陈宇
何益飞
雷发玲
黄金莲
陆海亮
李建华
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Infinitus China Co Ltd
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Infinitus China Co Ltd
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Priority to CN201810620296.5A priority Critical patent/CN108888579B/en
Publication of CN108888579A publication Critical patent/CN108888579A/en
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Publication of CN108888579B publication Critical patent/CN108888579B/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365Hydroxycarboxylic acids; Ketocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/737Galactomannans, e.g. guar; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations

Abstract

The present invention relates to biochemical articles fields, in particular to compound and the bath preparation containing the composition.The present invention provides a kind of composition and bath preparations.The composition includes following component:Mixture more than one or both of cocoyl isethionate, sodium sulfate of polyethenoxy ether of fatty alcohol, laurel alcohol sulfuric ester ammonium (TEXAPON ALS70), phthalyl tallow base amine, pearlescent flake, coconut oil fatty acid monoethanolamide, C12-13 alkanol lactate, cetostearyl alcohol, coconut oil diethanol amide (lauric acid amide of ethanol), fluorescent whitening agent ER, guar gum, alkyl glycosides, propyl betaine, honey.While having comprehensive washability, foam is fine and smooth and stablizes, mild to skin, can effective moisturizing, it is small to the irritation of skin, and there is good anti-microbial property.

Description

Composition and bath preparation containing the composition
Technical field
The present invention relates to biochemical articles fields, in particular to compound and the bath preparation containing the composition.
Background technique
Daily chemical product (Everyday chemicals, household chemicals), abbreviation daily use chemicals.Daily chemical product is Refer to household chemicals, be people on ordinary days common scientific and technological chemicals include shampoo, shower cream, skin care, hair care, cosmetics, Washing powder etc..It is divided into according to the frequency of use or range of articles:Daily necessities (or daily necessities), luxury Product.Have according to purposes division:Bath accessory, household items, kitchenware and sanitary ware, adornment, cosmetic product etc..
Household chemicals industry is as the improvement of people's living standards, the enhancing of people's purchasing power has a great development. Daily necessities include cosmetics, detergent, oral cavity household chemicals, cleaner special etc..And the development of daily cosmetics, in effectiveness Will be more careful in differentiation, it is functional stronger.
Shower cream is also known as bath oil, refers to a kind of liquid ceanser used when bathing, is a kind of common clear of modern Clean articles, the invention of bath oil is primarily to replace the sense of touch and effect of tradition cleaning soap.Bath oil contacts people's skin When do not have very hard feeling as soap, but the moisturizing effect for skin and bad.
Current market sales of shower cream articles are various in style, and quality discrepancy is also big.Usually only there is washing effect, function It can be single.Also, traditional shower cream joined a large amount of extremely strong surface-actives of alkalinity to improve cleaning force and ability of deoiling Agent, foaming agent, the ingredients such as soap base, and the skin of human body be it is weakly acidic, use for a long time can stimulate skin.It is more serious It is that the sebum film of skin can be also destroyed.Once losing sebum film, skin is highly susceptible to external injury.
Summary of the invention
In view of this, the present invention provides a kind of compound and the bath preparation containing the composition.The composition and shower Preparation, while having comprehensive washability, foam is fine and smooth and stablizes, mild to skin, can effective moisturizing, and With good anti-microbial property.
In order to achieve the above-mentioned object of the invention, the present invention provides following technical scheme:
The present invention provides a kind of compositions, including following component:Cocoyl isethionate, aliphatic alcohol polyethenoxy Ether sodium sulfate, laurel alcohol sulfuric ester ammonium, phthalyl tallow base amine, pearlescent flake, coconut oil fatty acid monoethanolamide, C12- 13 alkanol lactates, cetostearyl alcohol, citric acid, coconut oil diethanol amide, sodium citrate, fluorescent whitening agent ER, guar gum, Alkyl glycosides, propyl betaine, honey, light green pigment or combinations thereof.
In some specific embodiments of the invention, light green pigment is light green 1% aqueous solution of pigment in the composition.
In some specific embodiments of the invention, the composition is in terms of mass parts, including following component:
In some specific embodiments of the invention, the composition is in terms of mass parts, including following component:
The present invention provides application of the composition in the daily chemical product of preparation cleaning class.
In some specific embodiments of the invention, the daily chemical product is bath preparation.
In some specific embodiments of the invention, the bath preparation is shower cream, bath oil, shower gel, bath Salt or bath soap.
The present invention also provides a kind of bath preparations, including acceptable auxiliary material in the composition and daily chemical product.
In some specific embodiments of the invention, the bath preparation is in terms of mass parts, including following component:
In some specific embodiments of the invention, the bath preparation is in terms of mass parts, including following component:
In some specific embodiments of the invention, the bath preparation is shower cream, bath oil, shower gel, bath Salt or bath soap.
The present invention also provides the preparation methods of the bath preparation, take the component of formula ratio to mix, homogeneous, emulsification.
Moisturizing bath preparation of the invention can commonly use method generally in the art and be prepared, such as be heated to 70 ~80 DEG C, homogeneous, emulsification are cooled to room temperature, can be prepared by.
The present invention provides a kind of composition and bath preparations.The composition includes following component:Cocoyl ethoxy sulphur Sour sodium, sodium sulfate of polyethenoxy ether of fatty alcohol, laurel alcohol sulfuric ester ammonium, phthalyl tallow base amine, pearlescent flake, coconut grease Fat acid single ethanol amide, C12-13 alkanol lactate, cetostearyl alcohol, citric acid, coconut oil diethanol amide, sodium citrate, Fluorescent whitening agent ER, guar gum, alkyl glycosides, propyl betaine, honey, light green pigment or combinations thereof.There is comprehensive washing While ability, foam is fine and smooth and stablizes, mild to skin, can effective moisturizing, it is small to the irritation of skin, and have There is good anti-microbial property.
Specific embodiment
The invention discloses a kind of compound and containing the bath preparation of the composition, those skilled in the art can be used for reference Present disclosure is suitably modified realization of process parameters.In particular, it should be pointed out that all similar substitutions and modifications are to this field skill It is it will be apparent that they are considered as being included in the present invention for art personnel.Method of the invention and application by compared with Good embodiment is described, related personnel obviously can not depart from the content of present invention, in spirit and scope to as described herein Methods and applications are modified or appropriate changes and combinations, carry out implementation and application the technology of the present invention.
Moisturizing bath preparation of the invention can commonly use method generally in the art and be prepared, such as be heated to 70 ~80 DEG C, homogeneous, emulsification are cooled to room temperature, can be prepared by.
Raw materials used, auxiliary material and reagent can be by compound provided by the invention and bath preparation containing the composition Market is bought.
Below with reference to embodiment, the present invention is further explained:
Examples 1 to 7
In terms of mass parts, Examples 1 to 7 includes following component:
Comparative example 1~2
In terms of mass parts, comparative example 1~2 includes following component:
Embodiment 8 tests the moistening effect of the shower cream of embodiment 1-7
20~50 years old 100 people is selected, men and women is fifty-fifty, health, rule of life, and no skin disease is randomly divided into 5 groups, Every group of 20 people, every group is taken a shower using moistening bath obtained in embodiment respectively, is then 25 in test environment temperature DEG C, the moisture content of left forearm is measured in the environment that relative humidity is 60%, while examinee being allowed to keep tranquil.On left forearm Distinguished as the test section of moistening bath using moisture of skin analyzer the square Experimental Area for marking 2 4cm × 4cm 2 hours skin moisture content, record result after measurement shower.Concrete outcome is shown in Table 1.
Table 1:Shower cream moistening effect test result table
Note:Control group compared with experimental group,*P < 0.05,#< 0.01.
The detection of 9 bactericidal property of embodiment
According to GBl5979-2002, the bactericidal property for the shower cream that embodiment obtains is detected.
Sterilizing rate when test acts on 20 minutes.
The microorganism tested:Escherichia coli (ATCC 25922);To staphylococcus aureus (ATCC6538).
The bactericidal effect of the bath preparation of embodiment 1-7 is tested.Concrete outcome is shown in Table 2.
Table 2:Moistening bath sterilizing rate test result table
Group Staphylococcus aureus (%)
Embodiment 1 80
Embodiment 2 82
Embodiment 3 80
Embodiment 4 86
Embodiment 5 83
Embodiment 6 85
Embodiment 7 90
Comparative example 1 50#
Comparative example 2 56#
Note:Control group compared with experimental group,*P < 0.05,#< 0.01.
10 detergency test of embodiment
With the following method, detergency test is carried out.
1) preparation of artificial dirt
Mix oil formula:With butter, lard, vegetable oil mass ratio for 0.5:0.5:1 prepares, and its gross mass 5% is added Glycerin monostearate, this is artificial dirt.
Artificial dirt is set and is heated to 180 DEG C on electric furnace, stirring keeps this temperature 10min, and beaker is moved to electromagnetic agitation Device stirring, it is spare to naturally cool to required temperature.Temperature of defiling recommends reference:When room temperature is 20 DEG C, 80 DEG C of oil temperature are needed;Room temperature When being 25 DEG C, 45 DEG C of oil temperature are needed;When room temperature is lower than 17 DEG C or is higher than 27 DEG C, test should not be carried out, and need to carry out in air conditioning room. The Terg-O-Tometer of attached refrigerating plant should be used when necessary.
2) preparation of dirty piece
, along 10mm line is drawn, limitation will be defiled below this line to show on glass slide;Glass slide lower edge is drawn into 5mm line, To show the extra greasy dirt limitation of wiping below this line.
3) after newly purchase glass slide needs boil 15min in detergent solution, clear water washs to not hanging droplet and sets acidity again After impregnating 1h in washing lotion, clear water rinsing and distilled water flushing are set spare after drying box is dried.
4) preparation of standard dish washing detergent
14 parts of sodium alkyl benzene sulfonate are weighed, 1 part of ethoxylated alkyl sulfate, 5 parts of dehydrated alcohol, 5 parts of urea, is added water to It 100 parts, mixes, adjusts pH to 7~8 with hydrochloric acid or sodium hydroxide, it is spare.
5) it defiles
Clean glass slide is set in weighing frame with four for one group, is precisely weighed with assay balance and (is accurately to 1mg) Glass slide after weighing is sandwiched on film airing stand by m0 one by one, and clip should be clipped in glass slide ascender line or more, and film airing stand is set and wards off disk Interior preparation is defiled.
When greasy dirt is maintained at determining temperature, glass slide is removed from film airing stand one by one together with clip, holds clip Glass slide is immersed in greasy dirt to (1~2) s below 10mm ascender line, is slowly taken out, after drop slows under greasy dirt, is hung back Dirty piece is originally sequentially prepared on film airing stand.After greasy dirt solidification, by dirty piece remove with filter paper or absorbent cotton by under dirty piece along 5mm bottom The extra greasy dirt in side and two sides is wiped, then the absorbent cotton wiped clean of petroleum ether is speckled with tweezers folder.After hanging 4h at room temperature, It with assay balance accurate weighing is m1 in weighing frame.Every at this time group of dirt on piece dirt amount should ensure that (0.5 ± 0.05) g.
6) test procedure
The glass slide of the known amount of defiling is inserted into corresponding wash stand and prepares washing.
Spotter is powered on, wash temperature is set as 30 DEG C, and rotational speed is set as 160r/min, and wash time is set It is set to 3min.
5.00g sample to be tested is weighed in 2500mL hard water, after shaking up, measures 800mL test solution respectively in Terg-O-Tometer Three washing tubes in, when test solution temperature rises to 30 DEG C, the dirty piece of known weight is accordingly put into together with wash stand rapidly In washing tube, starts to count soaking time after last wash stand is put into washing tube, while rapidly installing blender, impregnate When 1min, start spotter, start to wash, when 3min, machine autostop rapidly removes blender, takes out wash stand, will It washes rear dirty piece and press from both sides one by one and hang on original film airing stand, hang and dirty piece is set into corresponding weighing frame after the 3h that dries in the air weigh as m2.
(5) oil cut rate ω=(m1-m2)/(m1-m0) is removed in result expression
In formula:M0 --- glass slide quality before defiling, g;M1 --- glass slide quality after defiling, g;M2 --- it is dirty after washing The quality of piece, g.
Concrete outcome is shown in Table 3.
Table 3:Detergency measure of merit result table
Group Remove oil cut rate (ω, %)
Embodiment 1 70
Embodiment 2 80
Embodiment 3 75
Embodiment 4 73
Embodiment 5 78
Embodiment 6 80
Embodiment 7 89
Comparative example 1 47#
Comparative example 2 53#
Note:Control group compared with experimental group,*P < 0.05,#< 0.01.
The test of 11 irritation of embodiment
It simulates irritant experiment to carry out in laboratory, experimenter (each 5 people of men and women) is in the embodiment of the present invention 1~7 of 1wt% The detergent compositions aqueous wash medium of offer is washed, and 25 ± 2 DEG C of water temperature, water used is regular tap water, and daily washing 2 times, 3 is small every time When, continuous 1 week.It is averaged, scores higher again after scoring for the irritation of wrist-watch skin according to the standard of following table, stimulation Property is smaller.
4 judgment criteria of table
5 irritation test data table of table
Group Irritation scores (dividing)
Embodiment 1 82
Embodiment 2 83
Embodiment 3 83
Embodiment 4 85
Embodiment 5 87
Embodiment 6 86
Embodiment 7 88
Comparative example 1 71*
Comparative example 2 73*
Note:Control group compared with experimental group,*P < 0.05,#< 0.01.
The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For member, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications are also answered It is considered as protection scope of the present invention.

Claims (10)

1. a kind of composition, which is characterized in that including following component:Cocoyl isethionate, fatty alcohol polyoxyethylene ether Sodium sulphate, laurel alcohol sulfuric ester ammonium, phthalyl tallow base amine, pearlescent flake, coconut oil fatty acid monoethanolamide, C12-13 Alkanol lactate, cetostearyl alcohol, citric acid, coconut oil diethanol amide, sodium citrate, fluorescent whitening agent ER, guar gum, alkane Base glucosides, propyl betaine, honey, light green pigment or combinations thereof.
2. composition according to claim 1, which is characterized in that the light green pigment is light green 1% aqueous solution of pigment.
3. composition according to claim 1 or 2, which is characterized in that in terms of mass parts, including following component:
4. composition according to claim 1 or 2, which is characterized in that in terms of mass parts, including following component:
5. application of the composition according to any one of claims 1 to 4 in the daily chemical product of preparation cleaning class.
6. application according to claim 5, which is characterized in that the daily chemical product is bath preparation.
7. application according to claim 6, which is characterized in that the bath preparation is shower cream, bath oil, shower Gel Curry, bath salt or bath soap.
8. bath preparation according to claim 7, which is characterized in that in terms of mass parts, including following component:
9. bath preparation according to claim 7 or 8, which is characterized in that in terms of mass parts, including following component:
10. the preparation method of bath preparation according to any one of claims 7 to 9, which is characterized in that take the group of formula ratio Divide mixing, homogeneous, emulsification.
CN201810620296.5A 2018-06-15 2018-06-15 Composition and bath preparation containing the same Active CN108888579B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112263512A (en) * 2020-11-01 2021-01-26 钟达金 Low-irritation and rich-foam cleaning composition and application thereof and shower gel

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106075251A (en) * 2016-08-23 2016-11-09 杨锦玲 Chinese medicine composition, its preparation and preparation method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106075251A (en) * 2016-08-23 2016-11-09 杨锦玲 Chinese medicine composition, its preparation and preparation method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
中国洗涤用品工业协会: "《中国洗涤用品企业大全》", 31 January 2002, 中国轻工业出版社 *
无限极(中国)有限公司: ""植雅滋润沐浴露"", 《HTTP://FTBA.NMPA.GOV.CN:8181/FTBAN/ITOWNET/HZP_BA/FW/PZ.JSP?PROCESSID=2017082815360692WDN&NID=2017082815360692WDN》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112263512A (en) * 2020-11-01 2021-01-26 钟达金 Low-irritation and rich-foam cleaning composition and application thereof and shower gel
CN112263512B (en) * 2020-11-01 2023-10-13 深圳市理然化妆品有限公司 Low-irritation and foam-rich cleaning composition and application thereof and shower gel

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