CN108853602A - A kind of intestinal lavage for animals, bowel lavage conduit coating - Google Patents
A kind of intestinal lavage for animals, bowel lavage conduit coating Download PDFInfo
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- CN108853602A CN108853602A CN201810845477.8A CN201810845477A CN108853602A CN 108853602 A CN108853602 A CN 108853602A CN 201810845477 A CN201810845477 A CN 201810845477A CN 108853602 A CN108853602 A CN 108853602A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/10—Inorganic materials
- A61L29/106—Inorganic materials other than carbon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/085—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/02—Methods for coating medical devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/06—Coatings containing a mixture of two or more compounds
Abstract
The invention discloses a kind of intestinal lavage for animals, bowel lavage conduit coating, belongs to intestinal lavage for animals, bowel lavage conduit coating processing technique field, be made of following parts by weight of component:50-60 parts of silica dispersions, 20-30 parts of phosphorylation PASELLI EASYGEL, 21-25 parts of guar gum, 18-22 parts of polyethylene glycol, 4-5 parts of 2,4 dichlorophenoxyacetic acid, 3-4 parts of dibutyl hydroxy toluene, 8-10 parts of silane coupling agent, 4-6 parts of lanthanum carbonate, 30-36 parts of modified filler.The reasonably combined raw material of the present invention, the service performance of intestinal lavage for animals, bowel lavage conduit is effectively promoted in the coating finally prepared, room temperature do not turn yellow, no blooming, do not spit it is white, do not fade, it is nontoxic to the human body non-stimulated, there is odorlessness, ageing-resistant performance, it is high anti-tear, resilience is splendid, is unlikely to deform, the features such as weak acid and alkali resistance, high-low temperature resistant, great market popularization value.
Description
Technical field
The invention belongs to intestinal lavages for animals, bowel lavage catheter fabrication technical field, and in particular to a kind of intestinal lavage for animals, bowel lavage conduit
Coating.
Background technique
The especially thinner tank body soft pliable of good, tank body is bent with tensile property for silicon rubber medical catheter.These features make
Obtaining silicon catheter can occur bending and deformation when entering and leaving.Medical catheter silicon rubber is for opposite solid high-temperature sulphurated siliastic
, it is liquid glue, there is good fluidity, vulcanization is fast, safer environmental protection, and the requirement of food-grade, medical treatment can be fully achieved.Mainly
The conduit of application has intestinal lavage, bowel lavage conduit, catheter, drainage tube, two-chamber pressure-measuring pipe etc..Method in order to solve the above problem, one
It is the formula for changing silicon rubber, reduces its tensile property to improve its hardness, but reduce in this way and carry out the soft of silicon rubber
Toughness and feel make conduit become fragile, easily break, is easy to aging.Second is that external seal wire is used when entering and leaving conduit, although this method row
It is effective, but so that operation is become cumbersome using seal wire, and seal wire must be extracted after placing conduit, such conduit can not be hard
Very, conduit pulls deformation, causes the pain of patient.Its use value is promoted by increasing coating on the surface of conduit, still
Existing coating haves the shortcomings that easy fracture, easy to fall off, performance is poor.
Summary of the invention
The purpose of the present invention is being directed to existing problem, a kind of intestinal lavage for animals, bowel lavage conduit coating are provided.The present invention closes
The service performance of intestinal lavage for animals, bowel lavage conduit is effectively promoted in reason collocation raw material, the coating finally prepared, and room temperature is constant
Huang, no blooming, do not spit it is white, do not fade, it is nontoxic to the human body non-stimulated, there is odorlessness, ageing-resistant performance, high anti-tear, resilience
It is splendid, be unlikely to deform, the features such as weak acid and alkali resistance, high-low temperature resistant, great market popularization value.
The present invention is achieved by the following technical solutions:
A kind of intestinal lavage for animals, bowel lavage conduit coating, are made of following parts by weight of component:50-60 parts of silica dispersions, phosphoric acid
Change PASELLI EASYGEL 20-30 parts, 21-25 parts of guar gum, 18-22 parts of polyethylene glycol, 4-5 parts of 2,4 dichlorophenoxyacetic acid, two
3-4 parts of butylated hydroxytoluene, 8-10 parts of silane coupling agent, 4-6 parts of lanthanum carbonate, 30-36 parts of modified filler.
Preferably, it is made of following parts by weight of component:55 parts of silica dispersions, phosphorylation PASELLI EASYGEL 25
It is part, 23 parts of guar gum, 20 parts of polyethylene glycol, 4.5 parts of 2,4 dichlorophenoxyacetic acid, 3.5 parts of dibutyl hydroxy toluene, silane coupled
9 parts of agent, 5 parts of lanthanum carbonate, 33 parts of modified filler.
Further, the preparation of the modified filler, includes the following steps:
(1)It according to weight ratio is 1 by sodium glycocholate and neopelex:1.2-1.4 is placed in reaction kettle, is then added
Dehydrated alcohol after stirring and evenly mixing, 6-30 drop ammonium hydroxide is instilled into reaction kettle, after persistently stirring 20-30min, by polyvinyl chloride tree
Rouge and ethylene vinyl acetate resin are 1 according to weight ratio:1.3-1.4 is added in reaction kettle, continues to obtain after stirring 40-50min
Material A is spare;
(2)By step(1)Resulting material A, which is placed in modification liquid, is impregnated, the time 1-2h of immersion treatment, while immersion
The sonicated for carrying out specific frequency obtains material B after processing;
(3)By step(2)Obtained material B is placed in extra-high tension unit, is handled using high hydrostatic pressure material B, processing
Pressure be 200-300MPa, time of processing is 7-9min;
(4)By step(3)Material B after middle high hydrostatic pressure processing, filtering, which is placed in baking oven, is dried 20-30min.
Further, the step(1)Temperature control in middle reaction kettle is 99-103 DEG C, and the pressure control of reaction kettle is
0.2-0.4MPa。
Further, the step(1)The parts by weight of middle dehydrated alcohol are that sodium glycocholate and neopelex are total
8-12 times of parts by weight.
Further, the step(1)The total weight parts of middle Corvic and ethylene vinyl acetate resin are sweet gallbladders
4-6 times of the total weight parts of sour sodium and neopelex total weight parts.
Further, the step(2)Middle modification liquid is made of following parts by weight of component:4- hexyl resorcin 4-5
Part, 3-5 parts of epsilon-polylysine, 4-6 parts of GINKGO BILOBA EXTRACT, α -4-5 parts of bisabolol, 0.7-0.9 parts of nanometer iron powder, RE phosphate
0.6-1 parts, 3-5 parts of polysorbate, 2-4 parts of glycerin monostearate, 300-400 parts of deionized water.
Further, the step(2)Middle material A and the weight ratio of modification liquid are 1:7-9.
Further, the step(2)The frequency of middle sound wave is 3-4kHz, sound intensity 100-140dB.
Further, the step(4)Dry temperature control is 50-60 DEG C.
The present invention has the following advantages that compared with prior art:
The present invention provides a kind of intestinal lavage for animals, bowel lavage conduit coating, reasonably combined plurality of raw materials ingredient, wherein silica
Dispersion liquid and polyethylene glycol it is reasonably combined constitute basis film forming matter, in contain a large amount of OH active group, with silicon rubber
Glue surface can be effectively combined reaction, form a kind of space network, ensure that the close knot between coating and silicon rubber
Close intensity, it is addition phosphorylation PASELLI EASYGEL, guar gum, 2,4- dichlorphenoxyacetic acid, dibutyl hydroxy toluene, silane coupled
Agent improves the compactness and corrosion resistance of coating, forms the knot of tissue of good electrochemical protection and physics radiation shielding action
Structure adds the transparency that lanthanum carbonate improves film forming agent in order to further enhance the quality of coating and the use value of silicon rubber, tool
There is good solidification, further increase the degree of combining closely of coating and silicon rubber, improve the mechanical performance of silicon rubber, also
It is using Corvic and ethylene vinyl acetate resin as matrix composition, to using polyvinyl chloride added with modified filler
Resin and ethylene vinyl acetate resin are modified moditied processing, first with sodium glycocholate and neopelex into
The rheological characteristic enhancing of row activation, Corvic and ethylene vinyl acetate resin, then places it in modification liquid and is soaked
It steeps, the nanometer iron powder in modification liquid mutually acts synergistically with RE phosphate, increases Corvic and ethylene vinyl acetate
The specific surface area of resin, 4- hexyl resorcin, epsilon-polylysine further promote its anticorrosive and antioxygenic property, assign it
The ability of weak acid resistant weak base, then its biological property is assigned by GINKGO BILOBA EXTRACT, α-bisabolol, guarantee that silicon rubber is safe and non-toxic,
Ultrasonication is carried out while modification liquid immersion treatment, accelerates molecular motion velocities, modification efficiency is improved, in conjunction with high hydrostatic
The effect of pressure enhance coating organize everywhere between bonding strength, and have adjusted the coefficient of thermal expansion of coating entirety, make itself and silicon rubber
Glue it is close, the bad phenomenons such as will not crack, fall off in use process.
Intestinal lavage for animals, the use of bowel lavage conduit is effectively promoted in the reasonably combined raw material of the present invention, the coating finally prepared
Performance, room temperature do not turn yellow, no blooming, do not spit it is white, do not fade, it is nontoxic to the human body non-stimulated, there is odorlessness, ageing-resistant
The features such as performance, height is anti-tear, and resilience is splendid, is unlikely to deform, weak acid and alkali resistance, high-low temperature resistant, great market popularization value.
Specific embodiment
Embodiment 1
A kind of intestinal lavage for animals, bowel lavage conduit coating, are made of following parts by weight of component:50 parts of silica dispersions, phosphorylation
20 parts of PASELLI EASYGEL, 21 parts of guar gum, 18 parts of polyethylene glycol, 4 parts of 2,4 dichlorophenoxyacetic acid, dibutyl hydroxy toluene 3
Part, 8 parts of silane coupling agent, 4 parts of lanthanum carbonate, 30 parts of modified filler.
Further, the preparation of the modified filler, includes the following steps:
(1)It according to weight ratio is 1 by sodium glycocholate and neopelex:1.2 are placed in reaction kettle, are then added anhydrous
Ethyl alcohol after stirring and evenly mixing, 6 drop ammonium hydroxide is instilled into reaction kettle, after persistently stirring 20min, by Corvic and ethylene-vinegar
Acetoacetic ester resin is 1 according to weight ratio:1.3 are added in reaction kettle, continue stir 40min after material A it is spare;
(2)By step(1)Resulting material A, which is placed in modification liquid, is impregnated, the time 1h of immersion treatment, while immersion into
The sonicated of row specific frequency obtains material B after processing;
(3)By step(2)Obtained material B is placed in extra-high tension unit, is handled using high hydrostatic pressure material B, processing
Pressure be 200MPa, time of processing is 7min;
(4)By step(3)Material B after middle high hydrostatic pressure processing, filtering, which is placed in baking oven, is dried 20min.
Further, the step(1)Temperature control in middle reaction kettle is 99 DEG C, and the pressure control of reaction kettle is
0.2MPa。
Further, the step(1)The parts by weight of middle dehydrated alcohol are that sodium glycocholate and neopelex are total
8 times of parts by weight.
Further, the step(1)The total weight parts of middle Corvic and ethylene vinyl acetate resin are sweet gallbladders
4 times of the total weight parts of sour sodium and neopelex total weight parts.
Further, the step(2)Middle modification liquid is made of following parts by weight of component:4 parts of 4- hexyl resorcin,
3 parts of epsilon-polylysine, 4 parts of GINKGO BILOBA EXTRACT, 4 parts of α-bisabolol, 0.7 part of nanometer iron powder, 0.6 part of RE phosphate, poly- sorb
3 parts of ester, 2 parts of glycerin monostearate, 300 parts of deionized water.
Further, the step(2)Middle material A and the weight ratio of modification liquid are 1:7.
Further, the step(2)The frequency of middle sound wave is 3kHz, sound intensity 100dB.
Further, the step(4)Dry temperature control is 50 DEG C.
Embodiment 2
A kind of intestinal lavage for animals, bowel lavage conduit coating, are made of following parts by weight of component:55 parts of silica dispersions, phosphorylation
25 parts of PASELLI EASYGEL, 23 parts of guar gum, 20 parts of polyethylene glycol, 4.5 parts of 2,4 dichlorophenoxyacetic acid, dibutyl hydroxy toluene
3.5 parts, 9 parts of silane coupling agent, 5 parts of lanthanum carbonate, 33 parts of modified filler.
Further, the preparation of the modified filler, includes the following steps:
(1)It according to weight ratio is 1 by sodium glycocholate and neopelex:1.3 are placed in reaction kettle, are then added anhydrous
Ethyl alcohol after stirring and evenly mixing, 18 drop ammonium hydroxide is instilled into reaction kettle, after persistently stirring 25min, by Corvic and ethylene-
Ethyl acetate resin is 1 according to weight ratio:1.35 are added in reaction kettle, continue stir 45min after material A it is spare;
(2)By step(1)Resulting material A, which is placed in modification liquid, is impregnated, the time 1.5h of immersion treatment, while immersion
The sonicated for carrying out specific frequency obtains material B after processing;
(3)By step(2)Obtained material B is placed in extra-high tension unit, is handled using high hydrostatic pressure material B, processing
Pressure be 250MPa, time of processing is 8min;
(4)By step(3)Material B after middle high hydrostatic pressure processing, filtering, which is placed in baking oven, is dried 25min.
Further, the step(1)Temperature control in middle reaction kettle is 101 DEG C, and the pressure control of reaction kettle is
0.3MPa。
Further, the step(1)The parts by weight of middle dehydrated alcohol are that sodium glycocholate and neopelex are total
10 times of parts by weight.
Further, the step(1)The total weight parts of middle Corvic and ethylene vinyl acetate resin are sweet gallbladders
5 times of the total weight parts of sour sodium and neopelex total weight parts.
Further, the step(2)Middle modification liquid is made of following parts by weight of component:4- hexyl resorcin 4.5
Part, is gathered 4 parts of epsilon-polylysine, 5 parts of GINKGO BILOBA EXTRACT, 4.5 parts of α-bisabolol, 0.8 part of nanometer iron powder, 0.8 part of RE phosphate
4 parts of sorb ester, 3 parts of glycerin monostearate, 350 parts of deionized water.
Further, the step(2)Middle material A and the weight ratio of modification liquid are 1:8.
Further, the step(2)The frequency of middle sound wave is 3.5kHz, sound intensity 120dB.
Further, the step(4)Dry temperature control is 55 DEG C.
Embodiment 3
A kind of intestinal lavage for animals, bowel lavage conduit coating, are made of following parts by weight of component:60 parts of silica dispersions, phosphorylation
30 parts of PASELLI EASYGEL, 25 parts of guar gum, 22 parts of polyethylene glycol, 5 parts of 2,4 dichlorophenoxyacetic acid, dibutyl hydroxy toluene 4
Part, 10 parts of silane coupling agent, 6 parts of lanthanum carbonate, 36 parts of modified filler.
Further, the preparation of the modified filler, includes the following steps:
(1)It according to weight ratio is 1 by sodium glycocholate and neopelex:1.4 are placed in reaction kettle, are then added anhydrous
Ethyl alcohol after stirring and evenly mixing, 30 drop ammonium hydroxide is instilled into reaction kettle, after persistently stirring 30min, by Corvic and ethylene-
Ethyl acetate resin is 1 according to weight ratio:1.4 are added in reaction kettle, continue stir 50min after material A it is spare;
(2)By step(1)Resulting material A, which is placed in modification liquid, is impregnated, the time 2h of immersion treatment, while immersion into
The sonicated of row specific frequency obtains material B after processing;
(3)By step(2)Obtained material B is placed in extra-high tension unit, is handled using high hydrostatic pressure material B, processing
Pressure be 300MPa, time of processing is 9min;
(4)By step(3)Material B after middle high hydrostatic pressure processing, filtering, which is placed in baking oven, is dried 30min.
Further, the step(1)Temperature control in middle reaction kettle is 103 DEG C, and the pressure control of reaction kettle is
0.4MPa。
Further, the step(1)The parts by weight of middle dehydrated alcohol are that sodium glycocholate and neopelex are total
12 times of parts by weight.
Further, the step(1)The total weight parts of middle Corvic and ethylene vinyl acetate resin are sweet gallbladders
6 times of the total weight parts of sour sodium and neopelex total weight parts.
Further, the step(2)Middle modification liquid is made of following parts by weight of component:5 parts of 4- hexyl resorcin,
5 parts of epsilon-polylysine, 6 parts of GINKGO BILOBA EXTRACT, 5 parts of α-bisabolol, 0.9 part of nanometer iron powder, 1 part of RE phosphate, polysorbate 5
Part, 4 parts of glycerin monostearate, 400 parts of deionized water.
Further, the step(2)Middle material A and the weight ratio of modification liquid are 1:9.
Further, the step(2)The frequency of middle sound wave is 4kHz, sound intensity 140dB.
Further, the step(4)Dry temperature control is 60 DEG C.
Comparative example 1
This comparative example 1 the commercially available Corvic of mass parts and the second such as changes into compared with Example 2, by modified filler
Alkene-ethyl acetate resin, method and step in addition to this are all the same.
Comparative example 2
This comparative example 2 compared with Example 2, saves step(2)In specific frequency sonicated, in addition to this method step
It is rapid all the same.
Comparative example 3
This comparative example 3 compared with Example 2, saves step(3)In high hydrostatic pressure processing, method and step in addition to this is equal
It is identical.
Comparative example 4
This comparative example 4 compared with Example 2, saves modified filler, and method and step in addition to this is all the same.
In order to compare effect of the present invention, the present invention selects existing commercially available same series-produced intestinal lavage for animals, bowel lavage to lead
Then pipe uses embodiment 2, comparative example 1, comparative example 2, comparative example 3, the method system of comparative example 4 respectively
Standby coating coats conduit, then measures its mechanical performance.
Specific experiment correlation data is as shown in table 1 below:
Table 1
Intestinal lavage for animals, filling is effectively promoted in the reasonably combined raw material of the present invention it can be seen from upper table 1, the coating finally prepared
The service performance of intestines conduit, room temperature do not turn yellow, no blooming, do not spit it is white, do not fade, it is nontoxic to the human body non-stimulated, there is nothing
The features such as smell, ageing-resistant performance, height is anti-tear, and resilience is splendid, is unlikely to deform, weak acid and alkali resistance, high-low temperature resistant, great market pushes away
Wide value.
Claims (10)
1. a kind of intestinal lavage for animals, bowel lavage conduit coating, which is characterized in that be made of following parts by weight of component:Silica dispersion
50-60 parts of liquid, 20-30 parts of phosphorylation PASELLI EASYGEL, 21-25 parts of guar gum, 18-22 parts of polyethylene glycol, 2,4 dichloro benzene
4-5 parts of fluoroacetic acid, 3-4 parts of dibutyl hydroxy toluene, 8-10 parts of silane coupling agent, 4-6 parts of lanthanum carbonate, 30-36 parts of modified filler.
2. a kind of intestinal lavage for animals, bowel lavage conduit coating according to claim 1, which is characterized in that by following parts by weight of component
It is made:55 parts of silica dispersions, 25 parts of phosphorylation PASELLI EASYGEL, 23 parts of guar gum, 20 parts of polyethylene glycol, 2,4- bis-
4.5 parts of chlorophenoxyacetic acid, 3.5 parts of dibutyl hydroxy toluene, 9 parts of silane coupling agent, 5 parts of lanthanum carbonate, 33 parts of modified filler.
3. a kind of intestinal lavage for animals according to claim 1 or claim 2, bowel lavage conduit coating, which is characterized in that the modified filler
Preparation, includes the following steps:
(1)It according to weight ratio is 1 by sodium glycocholate and neopelex:1.2-1.4 is placed in reaction kettle, is then added
Dehydrated alcohol after stirring and evenly mixing, 6-30 drop ammonium hydroxide is instilled into reaction kettle, after persistently stirring 20-30min, by polyvinyl chloride tree
Rouge and ethylene vinyl acetate resin are 1 according to weight ratio:1.3-1.4 is added in reaction kettle, continues to obtain after stirring 40-50min
Material A is spare;
(2)By step(1)Resulting material A, which is placed in modification liquid, is impregnated, the time 1-2h of immersion treatment, while immersion
The sonicated for carrying out specific frequency obtains material B after processing;
(3)By step(2)Obtained material B is placed in extra-high tension unit, is handled using high hydrostatic pressure material B, processing
Pressure be 200-300MPa, time of processing is 7-9min;
(4)By step(3)Material B after middle high hydrostatic pressure processing, filtering, which is placed in baking oven, is dried 20-30min.
4. a kind of intestinal lavage for animals, bowel lavage conduit coating according to claim 3, which is characterized in that the step(1)Middle reaction
Temperature control in kettle is 99-103 DEG C, and the pressure control of reaction kettle is 0.2-0.4MPa.
5. a kind of intestinal lavage for animals, bowel lavage conduit coating according to claim 3, which is characterized in that the step(1)In it is anhydrous
The parts by weight of ethyl alcohol are 8-12 times of sodium glycocholate and neopelex total weight parts.
6. a kind of intestinal lavage for animals, bowel lavage conduit coating according to claim 3, which is characterized in that the step(1)Middle polychlorostyrene
The total weight parts of vinyl and ethylene vinyl acetate resin are the total of sodium glycocholate and neopelex total weight parts
4-6 times of parts by weight.
7. a kind of intestinal lavage for animals, bowel lavage conduit coating according to claim 3, which is characterized in that the step(2)Middle modification
Liquid is made of following parts by weight of component:4-5 parts of 4- hexyl resorcin, 3-5 parts of epsilon-polylysine, 4-6 parts of GINKGO BILOBA EXTRACT, α-
4-5 parts of bisabolol, 0.7-0.9 parts of nanometer iron powder, 0.6-1 parts of RE phosphate, 3-5 parts of polysorbate, glycerol monostearate
2-4 parts of ester, 300-400 parts of deionized water.
8. a kind of intestinal lavage for animals, bowel lavage conduit coating according to claim 3, which is characterized in that the step(2)Middle material
The weight ratio of A and modification liquid is 1:7-9.
9. a kind of intestinal lavage for animals, bowel lavage conduit coating according to claim 3, which is characterized in that the step(2)Middle sound wave
Frequency be 3-4kHz, sound intensity 100-140dB.
10. a kind of intestinal lavage for animals, bowel lavage conduit coating according to claim 3, which is characterized in that the step(4)It is dry
Temperature control be 50-60 DEG C.
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CN201810845477.8A CN108853602A (en) | 2018-07-27 | 2018-07-27 | A kind of intestinal lavage for animals, bowel lavage conduit coating |
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CN201810845477.8A CN108853602A (en) | 2018-07-27 | 2018-07-27 | A kind of intestinal lavage for animals, bowel lavage conduit coating |
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CN101302345A (en) * | 2007-05-09 | 2008-11-12 | 上海西利康高新技术合作公司 | Modified water-soluble organosilicon for latex catheter and preparation thereof |
CN106075604A (en) * | 2016-08-12 | 2016-11-09 | 四川众药业有限公司 | A kind of medical catheter hydrophilic coating |
-
2018
- 2018-07-27 CN CN201810845477.8A patent/CN108853602A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020055721A1 (en) * | 1999-10-28 | 2002-05-09 | Maria Palasis | Biocompatible pharmaceutical articles |
CN101302345A (en) * | 2007-05-09 | 2008-11-12 | 上海西利康高新技术合作公司 | Modified water-soluble organosilicon for latex catheter and preparation thereof |
CN106075604A (en) * | 2016-08-12 | 2016-11-09 | 四川众药业有限公司 | A kind of medical catheter hydrophilic coating |
Non-Patent Citations (3)
Title |
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刘嘉等: "《航空橡胶与密封材料》", 30 November 2011 * |
罗明泉: "《常见有毒和危险化学品手册》", 31 July 1992 * |
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