CN106075604A - A kind of medical catheter hydrophilic coating - Google Patents

A kind of medical catheter hydrophilic coating Download PDF

Info

Publication number
CN106075604A
CN106075604A CN201610665468.1A CN201610665468A CN106075604A CN 106075604 A CN106075604 A CN 106075604A CN 201610665468 A CN201610665468 A CN 201610665468A CN 106075604 A CN106075604 A CN 106075604A
Authority
CN
China
Prior art keywords
hydrophilic
solids content
medical catheter
coating
coating solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201610665468.1A
Other languages
Chinese (zh)
Inventor
马英祥
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sichuan Zhong Yi Pharmaceutical Co Ltd
Original Assignee
Sichuan Zhong Yi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sichuan Zhong Yi Pharmaceutical Co Ltd filed Critical Sichuan Zhong Yi Pharmaceutical Co Ltd
Priority to CN201610665468.1A priority Critical patent/CN106075604A/en
Publication of CN106075604A publication Critical patent/CN106075604A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • A61L29/085Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • A61L29/10Inorganic materials
    • A61L29/106Inorganic materials other than carbon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00Materials or methods for coatings medical devices
    • A61L2420/06Coatings containing a mixture of two or more compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The present invention relates to technical field of medical instruments, disclose a kind of medical catheter hydrophilic coating, including the coating solution composition that there is the high molecular polymer of hydrophilic group or monomer and solids content is 5% 25%.Coating solution comprises the aqueous dispersion of the urethanes of a solids content 36% 46% and the polysiloxanes of a solids content 19% or silicone emulsion.It has good hydrophilicity, the most nontoxic, good with bonding catheter.

Description

A kind of medical catheter hydrophilic coating
Technical field
The present invention relates to technical field of medical instruments, particularly relate to a kind of medical catheter hydrophilic coating.
Background technology
Catheter, stomach tube are conventional plug-in type medical apparatus and instruments, owing to its needs are inserted in the patient, so to its table The flexibility in face and comfortableness have higher requirement.And hydroaropic substance has preferable hydrophilic, have and well lubricate effect Really, but hydroaropic substance is due to some material properties of itself, it is impossible to reach the requirement of medical apparatus and instruments articles for use, as to human body Toxic effect etc..
Therefore, a kind of medical catheter hydrophilic coating of research, use the comfort level of conduit, eliminate hydrophilic painting improving patient The toxic and side effects of layer, becomes skilled artisan's problem demanding prompt solution.
Summary of the invention
It is desirable to provide a kind of medical catheter hydrophilic coating, well solving the problems referred to above, it has well Hydrophilicity, the most nontoxic, good with bonding catheter.
The technical scheme is that a kind of medical catheter hydrophilic coating, including the high molecular polymerization with hydrophilic group Thing or monomer and the coating solution that solids content is 5%-25% form.
Further, described coating solution comprises the aqueous dispersion of urethanes of solids content 36%-46% Polysiloxanes or silicone emulsion with a solids content 19%.
Further, described coating solution is possibly together with the cross-linking agent of urethanes.
Further, the high molecular polymer described in hydrophilic group contains SiO2 nanoparticle.
The invention has the beneficial effects as follows: the present invention will have the high molecular polymer of hydrophilic group or monomer and solids content Coating solution for 5%-25% is crosslinked together, is formed and a kind of has good hydrophilicity, the most nontoxic and conduit Bonding good hydrophilic coating, compared with existing single hydrophilic coating or lubricant, the hydrophilic ability of the present invention improves More than 30%, when it is coated in catheter surface, lubricant effect is the best, and when patient inserts, comfortable cleaning, reaction is good.
Detailed description of the invention
In order to make the purpose of the present invention, technical scheme and advantage clearer, below the present invention is carried out further Describe in detail.
Embodiment one: the invention provides a kind of medical catheter hydrophilic coating, including the macromolecule with hydrophilic group Polymer or monomer and the coating solution that solids content is 5% form.
Coating solution comprises the aqueous dispersion of the urethanes of a solids content 36% and a solids content 19% Polysiloxanes or silicone emulsion.Coating solution is possibly together with the cross-linking agent of urethanes.There is the high score of hydrophilic group Sub-polymer contains SiO2 nanoparticle.
The present invention will have the high molecular polymer of hydrophilic group or monomer and coating solution is crosslinked together, forms one There is good hydrophilicity, the most nontoxic hydrophilic coating good with bonding catheter, it is demonstrated experimentally that above-mentioned hydrophilic coating Hydrophilic ability improves more than 27.8%, and when it is coated in catheter surface, lubricant effect is the best, when patient inserts, comfortable Cleaning, reaction is good.
Embodiment two: a kind of medical catheter hydrophilic coating, including high molecular polymer or the monomer with hydrophilic group With the coating solution composition that solids content is 25%.
Coating solution comprises the aqueous dispersion of the urethanes of a solids content 46% and a solids content 19% Polysiloxanes or silicone emulsion.Coating solution is possibly together with the cross-linking agent of urethanes.There is the high score of hydrophilic group Sub-polymer contains SiO2 nanoparticle.
It is demonstrated experimentally that the hydrophilic ability of above-mentioned hydrophilic coating improves more than 30.1%, when it is coated in catheter surface, profit Sliding effect is the best, and when patient inserts, comfortable cleaning, reaction is good.
The present invention will have the high molecular polymer of hydrophilic group or monomer and coating solution is crosslinked together, forms one There is good hydrophilicity, the most nontoxic hydrophilic coating good with bonding catheter, it is demonstrated experimentally that single with existing Hydrophilic coating or lubricant are compared, and the hydrophilic ability of the present invention improves more than 30%, when it is coated in catheter surface, and lubrication Effect is the best, and when patient inserts, comfortable cleaning, reaction is good.
Certainly, the present invention also can have other various embodiments, in the case of without departing substantially from present invention spirit and essence thereof, ripe Know those skilled in the art and can make various corresponding change and deformation according to the present invention, but these change and deformation accordingly All should belong to the protection domain of appended claims of the invention.

Claims (4)

1. a medical catheter hydrophilic coating, it is characterised in that: include high molecular polymer or the monomer with hydrophilic group With the coating solution composition that solids content is 5%-25%.
Medical catheter hydrophilic coating the most according to claim 1, it is characterised in that: described coating solution comprises a solid The aqueous dispersion of the urethanes of content 36%-46% and the polysiloxanes of a solids content 19% or siloxanes emulsus Liquid.
Medical catheter hydrophilic coating the most according to claim 1, it is characterised in that: described coating solution is possibly together with amino The cross-linking agent of Ethyl formate.
Medical catheter hydrophilic coating the most according to claim 1, it is characterised in that there is described in: the high score of hydrophilic group Sub-polymer contains SiO2Nanoparticle.
CN201610665468.1A 2016-08-12 2016-08-12 A kind of medical catheter hydrophilic coating Withdrawn CN106075604A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610665468.1A CN106075604A (en) 2016-08-12 2016-08-12 A kind of medical catheter hydrophilic coating

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610665468.1A CN106075604A (en) 2016-08-12 2016-08-12 A kind of medical catheter hydrophilic coating

Publications (1)

Publication Number Publication Date
CN106075604A true CN106075604A (en) 2016-11-09

Family

ID=57456867

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610665468.1A Withdrawn CN106075604A (en) 2016-08-12 2016-08-12 A kind of medical catheter hydrophilic coating

Country Status (1)

Country Link
CN (1) CN106075604A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108853602A (en) * 2018-07-27 2018-11-23 董子强 A kind of intestinal lavage for animals, bowel lavage conduit coating

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108853602A (en) * 2018-07-27 2018-11-23 董子强 A kind of intestinal lavage for animals, bowel lavage conduit coating

Similar Documents

Publication Publication Date Title
EP3280461B1 (en) Removable film forming gel compositions and methods for their application
RU2443734C2 (en) Organosilicon elastomeric composition
AU2011262362B2 (en) Antimicrobial lubricant
EP2554205B1 (en) Medical device with slideable coating, and syringe
JP5110609B2 (en) Preservative-containing silicone elastomer
JPWO2014017579A1 (en) Silicone rubber-based curable composition
WO2007075927B1 (en) Branched polyglycols and branched polyether functional organopolysiloxanes and coatings containing same
US11497828B2 (en) Removable film forming gel compositions featuring adhesion promoters
WO2010058902A3 (en) Thermosensitive composition preventing tissue adhesion and preparation method thereof
WO2016183102A1 (en) Non-stick siloxane compositions having a low water roll off angle
CN106075604A (en) A kind of medical catheter hydrophilic coating
JP2013227473A (en) Silicone rubber-based curable composition
US20180117221A1 (en) Coating agent and medical instrument surface treated with coating agent
JP3095330B2 (en) Film-forming composition
JP2013227474A (en) Silicone rubber-based curable composition
JP2020501646A5 (en)
CN106178137A (en) A kind of preparation method of medical catheter hydrophilic coating
CN106267376A (en) A kind of medical catheter preparation method of super hydrophilic antimicrobial coating
CN108112233A (en) It is a kind of to improve the cosmetic composition for turning viscous
CN106310478A (en) Super-hydrophilic antibacterial trachea cannula
CN106215249A (en) A kind of super hydrophilic catheter
CN106215302A (en) A kind of super hydrophilic antibacterial blood vessel microtubular
AU2017242171B9 (en) Liquid material for medical device coating and medical device having sliding coating film
CN115181275A (en) Foaming polyether silicone oil and preparation method thereof, and no-clean alcohol hand sanitizer containing foaming polyether silicone oil and hyaluronic acid and preparation method thereof
KR20190080324A (en) Composition for forming a film at room temperature and method for forming a film at room temperature using the same

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
WW01 Invention patent application withdrawn after publication

Application publication date: 20161109

WW01 Invention patent application withdrawn after publication