CN108853046A - A kind of breath freshening tablet suitable for chemotherapy patients - Google Patents

A kind of breath freshening tablet suitable for chemotherapy patients Download PDF

Info

Publication number
CN108853046A
CN108853046A CN201810803418.4A CN201810803418A CN108853046A CN 108853046 A CN108853046 A CN 108853046A CN 201810803418 A CN201810803418 A CN 201810803418A CN 108853046 A CN108853046 A CN 108853046A
Authority
CN
China
Prior art keywords
breath freshening
parcel
freshening
breath
tablet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810803418.4A
Other languages
Chinese (zh)
Inventor
李苗
赵永莉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanfang Hospital
First Affiliated Hospital of PLA Military Medical University
Original Assignee
First Affiliated Hospital of PLA Military Medical University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by First Affiliated Hospital of PLA Military Medical University filed Critical First Affiliated Hospital of PLA Military Medical University
Priority to CN201810803418.4A priority Critical patent/CN108853046A/en
Publication of CN108853046A publication Critical patent/CN108853046A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Abstract

The invention belongs to medical rehabilitation technical fields, specifically disclose a kind of breath freshening tablet suitable for chemotherapy patients, including freshening tablet ontology, the freshening tablet ontology includes edible breath freshening portion and the parcel that is wrapped in outside breath freshening portion, parcel is made by starch and natural gum, and there are also vitamin and coagulation factors between parcel and breath freshening portion;Parcel surface forms multiple protrusions.The breath freshening tablet can clean the oral cavity of chemotherapy patients, keep its breath freshening and avoid canker sore.

Description

A kind of breath freshening tablet suitable for chemotherapy patients
Technical field
The present invention relates to medical rehabilitation technical fields, and in particular to a kind of breath freshening tablet suitable for chemotherapy patients.
Background technique
As running down for environment is accelerated with people's rhythm of life, pressure increases, plus living habit is not paid attention to, in recent years Come, the cancer probability of people had been improved more in the past.The progress and continuous development of science and technology, but also can not be cured before many Disease has effective treatment method.For some patients for suffering from cancer, can be treated by the method for chemotherapy.But it is sick People is in chemotherapy, although cancer cell can be killed, can also damage normal cell, cause blood platelet low, easily cause mouth Chamber ulcer.When brushing teeth, toothbrush is easy to scratch patient's mouth, leads to bleeding patient because sharp, so it is not recommended that patient brushes Tooth, likewise, also it is not recommended that patient is gone to remove tooth stain with dental floss.But patient does not brush teeth and will lead to implication problem, shadow Ring patient comfort sense.
Summary of the invention
The purpose of the present invention is to provide a kind of breath freshening tablet suitable for chemotherapy patients, which can be right The oral cavity of chemotherapy patients is cleaned, and is kept its breath freshening and is avoided canker sore.
In order to achieve the above objectives, base case of the invention is as follows:A kind of breath freshening tablet suitable for chemotherapy patients, packet Include freshening tablet ontology, the freshening tablet ontology includes edible breath freshening portion and the package that is wrapped in outside breath freshening portion Portion, parcel are made by starch and natural gum, between parcel and breath freshening portion there are also vitamin and blood coagulation because Son;Parcel surface forms multiple protrusions.
Using having the beneficial effect that for this programme:1. breath freshening tablet includes parcel and breath freshening portion, and parcel Then be made of starch and natural gum, be both it is edible, it is non-hazardous to patient.
2, parcel outer surface has multiple protrusions, and patient is in chewing, the tooth friction of protrusion meeting and patient, by tooth On swill etc. wipe off, keep patient's mouth cleaning.
3, parcel and after starch enters in disease population, can be contacted and be divided with ptyalin made of starch Solution, so that the coagulation factor etc. of the inside is discharged, and these can help patient to improve canker sore.
4, there is breath freshening portion in parcel, on the one hand breath freshening portion can make pure and fresh patient's implication of patient, another Aspect, breath freshening portion and natural gum have very strong stickiness, can adsorb the swill etc. being scraped off, further Keep oral cleaning.
Preferred embodiment one:As the preferred embodiment of basic scheme, the breath freshening portion is chewing gum.Chewing gum conveniently takes , it is low in cost and edible.Patient can be with fresh breath by chew gum, and chewing gum stickiness with higher, Cooperate the stickiness of natural rubber again, the swill etc. scraped off by protrusion can be adhered to, keeps oral cleaning.
Preferred embodiment two:Preferably one preferred embodiment, protrusion are in truncated cone-shaped.Protrusion is easier in truncated cone-shaped will Swill in patient's mouth scrapes and will not damage patient's mouth.
Preferred embodiment three:Preferably two preferred embodiment.The protrusion is irregular to be arranged in freshening tablet ontology Surface.Protrusion is arranged in freshening tablet ontology in irregular, then for patient in chewing, the range that protrusion is contacted with patient's mouth is more Greatly, the effect of breath freshening is more preferable.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram of the breath freshening tablet embodiment suitable for chemotherapy patients of the present invention.
Specific embodiment
Below by specific embodiment, the present invention is described in further detail:
Appended drawing reference in Figure of description includes:Freshening tablet ontology 1, protrusion 2.
Embodiment is substantially as shown in Fig. 1:A kind of breath freshening tablet suitable for chemotherapy patients, including freshening tablet ontology 1, Freshening tablet ontology 1 includes edible breath freshening portion and the parcel that is wrapped in outside breath freshening portion, parcel with a thickness of 3-6mm.Parcel is by starch, natural gum, shrub althea flower, Sodium Polyacrylate, the pure and mild green tea powder of isomaltoketose by certain ratio Example is mixed, and because not generating chemical reaction between said components, ratio can be adjusted as needed, the ratio of starch 50% with On.There are also vitamin and coagulation factors between parcel and breath freshening portion;Parcel surface forms multiple raised 2.It is convex 2 are played in truncated cone-shaped and irregular is arranged in 1 surface of freshening tablet ontology.Protrusion 2 is easier in truncated cone-shaped will be in patient's mouth Swill scrapes and will not damage patient's mouth, and patient, in chewing, the range that protrusion 2 is contacted with patient's mouth is more Greatly, the effect of breath freshening is more preferable.Patient, especially chemotherapy patients, can be by chewing the breath freshening in fresh breath Piece, natural gum, starch and the Sodium Polyacrylate in parcel in the breath freshening tablet, the pure and mild green tea powder of isomaltoketose Be Deng all it is edible, it is harmless to patient.And parcel wraps breath freshening portion, can to avoid vitamin and blood coagulation because Leakage of the son when not chewing.When patient is in chewing, its oral cavity is first to contact with parcel, and patient generates in chewing Ptyalin can decompose the starch of parcel, escape vitamin and coagulation factor gradually, be applied to the oral cavity of patient Place.Isomalt can not only provide sweet taste, but also have hygroscopicity low, high stability, height endurability and low in calories etc. Feature, will not be cariogenic.Green tea powder can play the role of preliminary fresh breath.Shrub althea flower crude fibre rich in, reduction The nutriments such as sugar, vitamin C, amino acid, the effect that can play hemostasis reduces the generation of canker sore, and can be improved The mouthfeel when breath freshening tablet is chewed.In addition, breath freshening portion is chewing gum in the present embodiment.In vitamin and coagulation factor When evolution, the oral cavity of patient also can gradually chew gum, achieve the effect that fresh breath.
Patient can be with fresh breath by chew gum, and chewing gum stickiness with higher, then cooperates natural rubber Stickiness, can adhere to by 2 swill etc. that scrapes off of protrusion, keep oral cleaning.Parcel outer surface has multiple convex 2 are played, in chewing, the swill etc. on tooth can be wiped off with the tooth friction of patient, keep disease population patient by protrusion 2 Chamber cleaning.
Also contain Sodium Polyacrylate in this programme, after Sodium Polyacrylate and saliva contacts, absorbs the moisture in saliva, it can be with Expansion, the i.e. breath freshening tablet will not be with chewings and volume becomes smaller, opposite, volume can become larger, and connect to patients teeth Contact portion position can be bigger, also more preferable to the clean effect of residue in patients teeth.
By this breath freshening tablet and existing breath freshening object, (for example green arrow of commercially available chewing gum and mouthwash be such as on the market Relax visitor) look for being taken in the patient for doing chemotherapy respectively, wherein the breath freshening tablet in this offshoot program, chewing gum and mouthwash be all for It uses, i.e., uses 3-4 times daily daily;Breath freshening tablet and chewing gum are chewing, and each chew time is 8-15 minutes;It gargles The usage mode of water is to gargle 3-4 times daily, the use of the time is every time 30-40 seconds;Specific effect is as shown in the table:
By upper table it is found that using this programme breath freshening tablet, breath freshening and to the oral cleaning effect of patient more Well and chemotherapy patients can be helped to improve canker sore, be more applicable for chemotherapy patients.
What has been described above is only an embodiment of the present invention, and the common sense such as well known specific structure and characteristic are not made herein in scheme Excessive description.It, without departing from the structure of the invention, can be with it should be pointed out that for those skilled in the art Several modifications and improvements are made, these also should be considered as protection scope of the present invention, these all will not influence what the present invention was implemented Effect and patent practicability.The scope of protection required by this application should be based on the content of the claims, in specification The records such as specific embodiment can be used for explaining the content of claim.

Claims (4)

1. a kind of breath freshening tablet suitable for chemotherapy patients, it is characterised in that:Including freshening tablet ontology, the freshening tablet ontology Including edible breath freshening portion and the parcel being wrapped in outside breath freshening portion, parcel is made by starch and natural gum It forms, there are also vitamin and coagulation factors between parcel and breath freshening portion;Parcel surface forms multiple protrusions.
2. a kind of breath freshening tablet suitable for chemotherapy patients according to claim 1, it is characterised in that:The implication is clear New portion is chewing gum.
3. a kind of breath freshening tablet suitable for chemotherapy patients according to claim 2, it is characterised in that:Protrusion is in rotary table Shape.
4. a kind of breath freshening tablet suitable for chemotherapy patients according to claim 3, it is characterised in that:The protrusion is not Rule is arranged in freshening tablet body surface.
CN201810803418.4A 2018-07-20 2018-07-20 A kind of breath freshening tablet suitable for chemotherapy patients Pending CN108853046A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810803418.4A CN108853046A (en) 2018-07-20 2018-07-20 A kind of breath freshening tablet suitable for chemotherapy patients

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810803418.4A CN108853046A (en) 2018-07-20 2018-07-20 A kind of breath freshening tablet suitable for chemotherapy patients

Publications (1)

Publication Number Publication Date
CN108853046A true CN108853046A (en) 2018-11-23

Family

ID=64304111

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810803418.4A Pending CN108853046A (en) 2018-07-20 2018-07-20 A kind of breath freshening tablet suitable for chemotherapy patients

Country Status (1)

Country Link
CN (1) CN108853046A (en)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399154A (en) * 1980-06-30 1983-08-16 Nabisco Brands Inc. Coextruded chewing gum
CN1668210A (en) * 2002-07-15 2005-09-14 拜格-索伦森公司 Tabletted chewing gum sweet
CN1668208A (en) * 2002-09-24 2005-09-14 古木林科有限公司 Chewing gum comprising at least two different biodegradable polymers
CN1946303A (en) * 2004-04-20 2007-04-11 Wm.雷格利Jr.公司 Breath freshening confectionery products and methods of making and using same
CN101468109A (en) * 2007-12-29 2009-07-01 天津市中宝制药有限公司 Chewing gum for treating bleeding gingiva
CN101790322B (en) * 2007-08-10 2014-01-22 曼海姆/奥克森富特希德楚格股份公司 Rice starch in sugar free coatings
CN104431271A (en) * 2014-11-24 2015-03-25 黑龙江福和华星制药集团股份有限公司 Health care chewing gum containing Peruvian ginseng and rhizoma polygonati

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399154A (en) * 1980-06-30 1983-08-16 Nabisco Brands Inc. Coextruded chewing gum
CN1668210A (en) * 2002-07-15 2005-09-14 拜格-索伦森公司 Tabletted chewing gum sweet
CN1668208A (en) * 2002-09-24 2005-09-14 古木林科有限公司 Chewing gum comprising at least two different biodegradable polymers
CN1946303A (en) * 2004-04-20 2007-04-11 Wm.雷格利Jr.公司 Breath freshening confectionery products and methods of making and using same
CN101790322B (en) * 2007-08-10 2014-01-22 曼海姆/奥克森富特希德楚格股份公司 Rice starch in sugar free coatings
CN101468109A (en) * 2007-12-29 2009-07-01 天津市中宝制药有限公司 Chewing gum for treating bleeding gingiva
CN104431271A (en) * 2014-11-24 2015-03-25 黑龙江福和华星制药集团股份有限公司 Health care chewing gum containing Peruvian ginseng and rhizoma polygonati

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
丁纯孝,等: "《实用食品加工新技术》", 30 April 1992, 中国轻工业出版社 *
朱洪法,等: "《精细化工常用原材料手册》", 31 December 2003, 金盾出版社 *

Similar Documents

Publication Publication Date Title
Yaegaki et al. Tongue brushing and mouth rinsing as basic treatment measures for halitosis
JP4111916B2 (en) Composition for alleviating xerostomia and treating related diseases
CN101365778B (en) Cleaning composition
JP2009528352A (en) Oral hygiene products and their use
CN108685833A (en) Containing propolis, Radix Notoginseng, moutan bark, the coptis, Radix Glycyrrhizae toothpaste and preparation method thereof
CN105147612A (en) Oral cavity refreshing spray agent
CN105125690A (en) Oral anti-inflammation spray
CN105125425A (en) Oral anti-inflammation collutory
CN105106077A (en) Tooth protection collutory
US6475471B1 (en) System and method for applying oral fluid absorbing material to dental arches, with application in treatment of periodontal gum disease
CN101972215A (en) Chitosan oligosaccharide oral cavity cleaning tablet
TWI359679B (en) Antiplaque confectionery dental composition
US11723847B2 (en) Dual component oral composition for enhancing remineralization of teeth
CN108853046A (en) A kind of breath freshening tablet suitable for chemotherapy patients
US10813878B2 (en) Oral health composition
US7955591B1 (en) Oral fluid absorbing compositions and system for application thereof in a method of dental arch treatment and teeth recalcification
US5861169A (en) Hard candy with tooth plaque-neutralizing effect comprising an ammonium salt
US6322772B1 (en) Methodology for treatment of the dental arches and periodontal tissue
CN101406435B (en) Use of radish chitin-binding protein in preparing dental health product
Walton et al. Elder oral assessment and care
CN104414898A (en) Enteromorpha prolifera toothpaste
Basavaraj et al. Halitosis: A review
CN105125416A (en) Oral fresh collutory
CN106309170A (en) Breath refreshing oral cavity cleaning agent
CN110200824A (en) A kind of sugar-free toothpaste and its production method containing resveratrol

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20181123

RJ01 Rejection of invention patent application after publication