CN108839405A - Anti-bacterial hydrogel and preparation method thereof - Google Patents
Anti-bacterial hydrogel and preparation method thereof Download PDFInfo
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- CN108839405A CN108839405A CN201810670197.8A CN201810670197A CN108839405A CN 108839405 A CN108839405 A CN 108839405A CN 201810670197 A CN201810670197 A CN 201810670197A CN 108839405 A CN108839405 A CN 108839405A
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- 239000000017 hydrogel Substances 0.000 title claims abstract description 29
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 24
- 238000002360 preparation method Methods 0.000 title claims abstract description 13
- 239000010410 layer Substances 0.000 claims abstract description 51
- 239000000499 gel Substances 0.000 claims abstract description 34
- 241000894006 Bacteria Species 0.000 claims abstract description 19
- 229920002678 cellulose Polymers 0.000 claims abstract description 18
- 239000001913 cellulose Substances 0.000 claims abstract description 18
- 108010010803 Gelatin Proteins 0.000 claims abstract description 17
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000008273 gelatin Substances 0.000 claims abstract description 17
- 229920000159 gelatin Polymers 0.000 claims abstract description 17
- 235000019322 gelatine Nutrition 0.000 claims abstract description 17
- 235000011852 gelatine desserts Nutrition 0.000 claims abstract description 17
- 239000004094 surface-active agent Substances 0.000 claims abstract description 17
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims abstract description 16
- 239000004372 Polyvinyl alcohol Substances 0.000 claims abstract description 15
- 229920002451 polyvinyl alcohol Polymers 0.000 claims abstract description 15
- 239000011241 protective layer Substances 0.000 claims abstract description 15
- SOQBVABWOPYFQZ-UHFFFAOYSA-N oxygen(2-);titanium(4+) Chemical compound [O-2].[O-2].[Ti+4] SOQBVABWOPYFQZ-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229920000742 Cotton Polymers 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 229920000136 polysorbate Polymers 0.000 claims description 4
- QQGISFDJEJMKIL-JAIQZWGSSA-N (5z)-5-[[3-(hydroxymethyl)thiophen-2-yl]methylidene]-10-methoxy-2,2,4-trimethyl-1h-chromeno[3,4-f]quinolin-9-ol Chemical group C1=CC=2NC(C)(C)C=C(C)C=2C2=C1C=1C(OC)=C(O)C=CC=1O\C2=C/C=1SC=CC=1CO QQGISFDJEJMKIL-JAIQZWGSSA-N 0.000 claims description 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims 2
- 240000007594 Oryza sativa Species 0.000 claims 1
- 235000007164 Oryza sativa Nutrition 0.000 claims 1
- 239000004411 aluminium Substances 0.000 claims 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims 1
- 229910052782 aluminium Inorganic materials 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 125000005456 glyceride group Chemical group 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 235000009566 rice Nutrition 0.000 claims 1
- 239000004408 titanium dioxide Substances 0.000 claims 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract description 3
- 230000035699 permeability Effects 0.000 abstract description 3
- 208000026935 allergic disease Diseases 0.000 abstract description 2
- 230000007815 allergy Effects 0.000 abstract description 2
- 230000000845 anti-microbial effect Effects 0.000 description 3
- 150000002085 enols Chemical class 0.000 description 3
- 239000000758 substrate Substances 0.000 description 3
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- FFRBMBIXVSCUFS-UHFFFAOYSA-N 2,4-dinitro-1-naphthol Chemical compound C1=CC=C2C(O)=C([N+]([O-])=O)C=C([N+]([O-])=O)C2=C1 FFRBMBIXVSCUFS-UHFFFAOYSA-N 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 241000191940 Staphylococcus Species 0.000 description 1
- 206010053615 Thermal burn Diseases 0.000 description 1
- 239000004964 aerogel Substances 0.000 description 1
- 208000030961 allergic reaction Diseases 0.000 description 1
- 230000003487 anti-permeability effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/32—Layered products comprising a layer of synthetic resin comprising polyolefins
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B3/00—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form
- B32B3/26—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layer; characterised by a layer with cavities or internal voids ; characterised by an apertured layer
- B32B3/266—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layer; characterised by a layer with cavities or internal voids ; characterised by an apertured layer characterised by an apertured layer, the apertures going through the whole thickness of the layer, e.g. expanded metal, perforated layer, slit layer regular cells B32B3/12
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B33/00—Layered products characterised by particular properties or particular surface features, e.g. particular surface coatings; Layered products designed for particular purposes not covered by another single class
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B5/00—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts
- B32B5/02—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by structural features of a fibrous or filamentary layer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B5/00—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts
- B32B5/02—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by structural features of a fibrous or filamentary layer
- B32B5/08—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by structural features of a fibrous or filamentary layer the fibres or filaments of a layer being of different substances, e.g. conjugate fibres, mixture of different fibres
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
- C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
- C08J3/075—Macromolecular gels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2262/00—Composition or structural features of fibres which form a fibrous or filamentary layer or are present as additives
- B32B2262/06—Vegetal fibres
- B32B2262/062—Cellulose fibres, e.g. cotton
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2262/00—Composition or structural features of fibres which form a fibrous or filamentary layer or are present as additives
- B32B2262/08—Animal fibres, e.g. hair, wool, silk
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2262/00—Composition or structural features of fibres which form a fibrous or filamentary layer or are present as additives
- B32B2262/14—Mixture of at least two fibres made of different materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/70—Other properties
- B32B2307/714—Inert, i.e. inert to chemical degradation, corrosion
- B32B2307/7145—Rot proof, resistant to bacteria, mildew, mould, fungi
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/70—Other properties
- B32B2307/724—Permeability to gases, adsorption
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2389/00—Characterised by the use of proteins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2401/00—Characterised by the use of cellulose, modified cellulose or cellulose derivatives
- C08J2401/02—Cellulose; Modified cellulose
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
- C08K3/20—Oxides; Hydroxides
- C08K3/22—Oxides; Hydroxides of metals
- C08K2003/2237—Oxides; Hydroxides of metals of titanium
- C08K2003/2241—Titanium dioxide
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K2201/00—Specific properties of additives
- C08K2201/011—Nanostructured additives
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention provides a kind of anti-bacterial hydrogel and preparation method thereof, anti-bacterial hydrogel includes basal layer, gel layer and protective layer.By weight, gel layer is made by following components:10-38 parts of gelatin, 16-25 parts of bacteria cellulose, 12-18 parts of polyvinyl alcohol, 3-12 parts of silver ion, 1-4 parts of nano-titanium dioxide and 1-2 parts of surfactant, gel layer have mesh and with a thickness of 0.5mm-3mm, and the partial size of nano-aluminium oxide is 5-25nm.Hydrogel preparation method of the invention is simple, using comfortable, allergy will not be caused to patient, and antibacterial effect is excellent, permeability is good.
Description
Technical field
The present invention relates to field of medical materials, and in particular to a kind of anti-bacterial hydrogel and preparation method thereof.
Background technique
Hydrogel is widely used in the field of medicine at present, has obtained many researchs.For example, being suitable for wound, scald etc.
The hydrogel of protecting wound surface and treatment, the hydrogel etc. for cooling.However, these aerogel dressing products are generally thicker, thoroughly
Gas ability is bad, cutaneous eubolism, and allergic reaction can be even generated when being suitable for infant.In addition, mesh
The anti-microbial property of preceding hydrogel, which remains on, to be required further improvement.
Summary of the invention
In order to solve the above technical problems, the present invention provides a kind of anti-bacterial hydrogel, preparation is simple, at low cost, and has
Good anti-microbial property and gas permeability, using comfortable.
To achieve the above object, the invention adopts the following technical scheme:
On the one hand, the present invention provides a kind of anti-bacterial hydrogels, including basal layer, gel layer and protective layer, with weight
Meter, the gel layer are made by following components:10-38 parts of gelatin, 16-25 parts of bacteria cellulose, 12-18 parts of polyvinyl alcohol, silver
3-12 parts of ion, 1-4 parts of nano-titanium dioxide and 1-2 parts of surfactant, gel layer have mesh and with a thickness of 0.5mm-
3mm, the partial size of the nano-aluminium oxide are 5-25nm.
Preferably, basal layer is formed by silk and cotton fiber shuffling.
Preferably, the surfactant is tween or glycerin monostearate.
Preferably, protective layer is PE film or PP film.
Preferably, by weight, the gel layer is made by following components:10 parts of gelatin, 16 parts of bacteria cellulose, poly- second
12 parts of enol, 3 parts of silver ion, 1 part of nano-titanium dioxide and 1 part of surfactant.
Preferably, by weight, the gel layer is made by following components:38 parts of gelatin, 25 parts of bacteria cellulose, poly- second
18 parts of enol, 12 parts of silver ion, 4 parts of nano-titanium dioxide and 2 parts of surfactant.
Preferably, by weight, the gel layer is made by following components:22 parts of gelatin, 20 parts of bacteria cellulose, poly- second
16 parts of enol, 8 parts of silver ion, 3 parts of nano-aluminium oxide and 1.5 parts of surfactant.
On the other hand, the present invention provides the preparation method of above-mentioned anti-bacterial hydrogel, include the following steps:
(1) with gelatin, bacteria cellulose, polyvinyl alcohol, silver ion, nano-titanium dioxide part and the preparation of surfactant part
Gel layer, and mesh is formed wherein;
(2) basal layer and protective layer are separately connected on two opposite sides of gel layer.
By above-mentioned technical proposal, compared with prior art, the present invention is had the following advantages that:It is anti-that the present invention provides one kind
The components such as bacterium hydrogel, including bacteria cellulose, polyvinyl alcohol and silver ion have good anti-microbial property, and permeability
It is good, it has a good application prospect.
Specific embodiment
Specific embodiments of the present invention will be described in further detail below.It should be understood that following embodiment is only used
In illustrating the present invention, limitation of the scope of the invention but should not be understood as.
Embodiment 1
A kind of anti-bacterial hydrogel, including basal layer, gel layer and protective layer.By weight, gel layer is by following components system
?:10 parts of gelatin, 16 parts of bacteria cellulose, 12 parts of polyvinyl alcohol, 3 parts of silver ion, 1 part of nano-titanium dioxide and surfactant
1 part.Gel layer has mesh and with a thickness of 0.5mm, and the partial size of nano-aluminium oxide is 5nm.Basal layer is fine by silk and cotton
Dimension shuffling forms, and surfactant is tween, and protective layer is PE film.The preparation method of anti-bacterial hydrogel, includes the following steps:
(1) gel layer is prepared with gelatin, bacteria cellulose, polyvinyl alcohol, silver ion, nano-titanium dioxide part and surfactant part,
And mesh is formed wherein;(2) bonding substrates layer and protective layer are distinguished on two opposite sides of gel layer.
Embodiment 2
A kind of anti-bacterial hydrogel, including basal layer, gel layer and protective layer.By weight, gel layer is by following components system
?:38 parts of gelatin, 25 parts of bacteria cellulose, 18 parts of polyvinyl alcohol, 12 parts of silver ion, 4 parts of nano-titanium dioxide and surface-active
2 parts of agent.Gel layer has mesh and with a thickness of 3mm, and the partial size of nano-aluminium oxide is 25nm.Basal layer is fine by silk and cotton
Dimension shuffling forms, and surfactant is tween, and protective layer is PE film.The preparation method of anti-bacterial hydrogel, includes the following steps:
(1) gel layer is prepared with gelatin, bacteria cellulose, polyvinyl alcohol, silver ion, nano-titanium dioxide part and surfactant part,
And mesh is formed wherein;(2) bonding substrates layer and protective layer are distinguished on two opposite sides of gel layer.
Embodiment 3
A kind of anti-bacterial hydrogel, including basal layer, gel layer and protective layer.By weight, gel layer is by following components system
?:22 parts of gelatin, 20 parts of bacteria cellulose, 16 parts of polyvinyl alcohol, 8 parts of silver ion, 3 parts of nano-aluminium oxide and surface-active
1.5 parts of agent.Gel layer has mesh and with a thickness of 1.5mm, and the partial size of nano-aluminium oxide is 18nm.Basal layer by silk with
Cotton fiber shuffling forms, and surfactant is glycerin monostearate, and protective layer is PP film.The preparation method of anti-bacterial hydrogel,
Include the following steps:(1) gelatin, bacteria cellulose, polyvinyl alcohol, silver ion, nano-titanium dioxide part and surfactant are used
Part prepares gel layer, and forms mesh wherein;(2) bonding substrates layer and protection are distinguished on two opposite sides of gel layer
Layer.
Anti-bacterial hydrogel preparation of the invention is simple, through experimental test, uses 30, for three days on end, daily two to infant
Secondary, without any allergy, to golden yellow staphylococcus, Escherichia coli have a good bacteriostasis, and good permeability, to skin without
Any damage, thus it is suitable for multiple types patient.
The above is only a preferred embodiment of the present invention, it is not intended to restrict the invention, it is noted that for this skill
For the those of ordinary skill in art field, without departing from the technical principles of the invention, can also make it is several improvement and
Modification, these improvements and modifications also should be regarded as protection scope of the present invention.
Claims (8)
1. a kind of anti-bacterial hydrogel, including basal layer, gel layer and protective layer, it is characterised in that:By weight, the gel layer
It is made by following components:10-38 parts of gelatin, 12-18 parts of polyvinyl alcohol, 3-12 parts of silver ion, is received 16-25 parts of bacteria cellulose
1-4 parts and surfactant 1-2 parts of rice titanium dioxide, gel layer have mesh and with a thickness of 0.5mm-3mm, three oxygen of nanometer
The partial size for changing two aluminium is 5-25nm.
2. anti-bacterial hydrogel according to claim 1, it is characterised in that:The basal layer by silk and cotton fiber shuffling and
At.
3. anti-bacterial hydrogel according to claim 1, it is characterised in that:The surfactant is tween or monostearate
Glyceride.
4. anti-bacterial hydrogel according to claim 1, it is characterised in that:The protective layer is PE film or PP film.
5. anti-bacterial hydrogel according to claim 1, it is characterised in that:By weight, the gel layer is by following components
It is made:10 parts of gelatin, 16 parts of bacteria cellulose, 12 parts of polyvinyl alcohol, 3 parts of silver ion, 1 part of nano-titanium dioxide and surface-active
1 part of agent.
6. anti-bacterial hydrogel according to claim 1, it is characterised in that:By weight, the gel layer is by following components
It is made:38 parts of gelatin, 25 parts of bacteria cellulose, 18 parts of polyvinyl alcohol, 12 parts of silver ion, 4 parts of nano-titanium dioxide and surface are living
2 parts of agent of property.
7. anti-bacterial hydrogel according to claim 1, it is characterised in that:By weight, the gel layer is by following components
It is made:22 parts of gelatin, 20 parts of bacteria cellulose, 16 parts of polyvinyl alcohol, 8 parts of silver ion, 3 parts of nano-aluminium oxide and surface are living
1.5 parts of agent of property.
8. a kind of preparation method of anti-bacterial hydrogel described in claim 1, which is characterized in that include the following steps:
(1) gel is prepared with gelatin, bacteria cellulose, polyvinyl alcohol, silver ion, nano-titanium dioxide part and surfactant part
Layer, and mesh is formed wherein;
(2) basal layer and protective layer are separately connected on two opposite sides of gel layer.
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CN201810670197.8A CN108839405A (en) | 2018-06-26 | 2018-06-26 | Anti-bacterial hydrogel and preparation method thereof |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110524966A (en) * | 2019-09-02 | 2019-12-03 | 同曦集团有限公司 | A kind of antibacterial wallpaper and preparation method thereof |
US20220046911A1 (en) * | 2020-08-17 | 2022-02-17 | South Bay International, Inc. | Slow-release silk thread and method for preparing the same |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104043144A (en) * | 2014-07-03 | 2014-09-17 | 湖北科技学院 | Natural polysaccharide/nano-TiO2 composite light-sensitive antimicrobial hydrogel dressing and radiation synthesis method thereof |
-
2018
- 2018-06-26 CN CN201810670197.8A patent/CN108839405A/en not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104043144A (en) * | 2014-07-03 | 2014-09-17 | 湖北科技学院 | Natural polysaccharide/nano-TiO2 composite light-sensitive antimicrobial hydrogel dressing and radiation synthesis method thereof |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110524966A (en) * | 2019-09-02 | 2019-12-03 | 同曦集团有限公司 | A kind of antibacterial wallpaper and preparation method thereof |
CN110524966B (en) * | 2019-09-02 | 2021-12-10 | 同曦集团有限公司 | Antibacterial wallpaper and preparation method thereof |
US20220046911A1 (en) * | 2020-08-17 | 2022-02-17 | South Bay International, Inc. | Slow-release silk thread and method for preparing the same |
CN114150395A (en) * | 2020-08-17 | 2022-03-08 | 嘉兴中科奥度新材料有限公司 | Preparation method and product of lasting acarid-expelling and acarid-killing silk thread |
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