CN108815405A - External-applicationtraditional traditional Chinese medicinal and preparation method thereof for treating arthralgia - Google Patents
External-applicationtraditional traditional Chinese medicinal and preparation method thereof for treating arthralgia Download PDFInfo
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Abstract
This programme discloses a kind of for treating the External-applicationtraditional traditional Chinese medicinal of arthralgia of the technical field of pharmaceuticals for the treatment of pain, including component and the parts by weight of component be that 6~8 parts of Radix Angelicae Pubescentis, 3~5 parts of long-nosed pit viper, 4~6 parts of fresh waxgourd peel, fresh corn must 4~6 parts, 4~6 parts of agalloch eaglewood, 5~7 parts of semen litchi, 5~7 parts of the rhizome of davallia, 5~7 parts of dragon's blood, 6~8 parts of borneol, 6~8 parts of peppermint oil, 50 parts of white wine.This programme plays slowly to solve the drug effect of existing arthralgia therapeutic agent, and technical problem easy to recur after curing, from clearing and activating the channels and collaterals, promoting blood circulation qi-regulating, the angle of scattered stasis detumescence joint channels and collaterals are carried out with the recovery of function, keep channels and collaterals unobstructed, accelerate scalp to absorb, it so can quickly drug effect play, treating both manifestation and root cause of disease makes pain uneasy to recur.
Description
Technical field
The present invention relates to the technical field of pharmaceuticals for the treatment of pain, and in particular in a kind of external application for treating arthralgia
Drug composition and preparation method thereof.
Background technique
Osteoarthropathy is also known as osteoarthritis, retrogression arthritis, hypertrophic arthritis, senescent arthritis etc..It is one
The person in middle and old age of arthralgia and joint function disturbance are normal caused by kind becomes due to articular cartilage arthritis osteoarthritis degenerative bone
See disease.China is more than 200,000,000 people with Bones and joints patient.Research data show common people at 40 years old or more, almost 90%
Weight-bearing joints have retrogression pathological changes, wherein there is 25% or more crowd with hyperostosis, with advancing age, this pass
Section lesion is on the rise, and causes patient's body numbness, pain, swelling, movable function limited, individual serious forfeiture labour energy
Power be can't take care of oneself, and great pain is brought.
Arthralgia patient mostly uses endo-medicine or outer patch drug or even operative treatment, expensive, and effect is most
Situation is unsatisfactory, and Relapse rate, causes very big burden to patient.Conventional therapy osteoarthropathy stays body anti-inflammatory drugs using non-
The drugs such as (anodyne), resisting hyperosteogeny Chinese patent drug and calcium tablet, can also be used massage, traction, physical therapy, acupuncture-moxibustion, small needle knife and hand
The treatment methods such as art, though can momentary alleviations shape disease, be easy to recur after stopping treatment, it is however generally that recurrence period March with
It is interior, and the therapeutic effect of pain is played slowly, usually pain can be enable to alleviate at 13 days or more.
Summary of the invention
The invention is intended to provide a kind of External-applicationtraditional traditional Chinese medicinal and preparation method thereof for treating arthralgia, to solve
The drug effect of existing arthralgia therapeutic agent plays slowly, and technical problem easy to recur after healing.
The External-applicationtraditional traditional Chinese medicinal for being used to treat arthralgia in this programme, it is characterised in that：Including component and group
Point parts by weight be 6~8 parts of Radix Angelicae Pubescentis, 3~5 parts of long-nosed pit viper, 4~6 parts of fresh waxgourd peel, fresh corn must 4~6 parts, 4~6 parts of agalloch eaglewood,
5~7 parts of semen litchi, 5~7 parts of the rhizome of davallia, 5~7 parts of dragon's blood, 6~8 parts of borneol, 6~8 parts of peppermint oil, 50 parts of white wine.
The principle and beneficial effect of this programme be：Arthralgia thinks in Chinese medicine angle, not general rule pain, however chill is wet
Heresy is to lead to one of principal element of arthralgia, if it is long pain caused by external force collision, also in that gas at shock
Blood is obstructed, and there are the stagnant situations of the stasis of blood to lead to pain, and hitting injury can also make joint be easy affection of exogenous wind-cold damp evil.
It joined the Radix Angelicae Pubescentis with wind-expelling and cold-expelling efficacy and long-nosed pit viper in this programme, it can be cold to what is hidden in joint channels and collaterals
It is wet to be dispelled；However blockage of main and collateral channels generally also can be accounted for synchronization while expelling wind and clearing away cold with the symptom of swelling
Make channels and collaterals in general, being just conducive to excrete pathogenic cold-damp by channels and collaterals in this way, so the present invention is equipped with waxgourd peel and corn again
Must, the two and Radix Angelicae Pubescentis and long-nosed pit viper compatibility, synergy can achieve the effect that good clearing and activating the channels and collaterals, expelling wind and clearing away cold.It is equipped with again
Have effects that the agalloch eaglewood of qi-regulating and semen litchi, and have effects that the rhizome of davallia and dragon's blood of promoting blood circulation, is managed with the use of promoting blood circulation is reached
The effect of gas, qi and blood circulation smoothly on the basis of, can speed up the unobstructed effect of joint channels and collaterals, channels and collaterals are unobstructed, and feeling of pain disappears
It removes.
Borneol and peppermint oil is added on the basis of above-mentioned medication composition, so that manufactured drug is in grease-like, forms oleophylic
Hydrophilic pharmaceutical composition promotes scalp to absorb, accelerates the performance of drug effect by being applied with.
To sum up, the present invention carries out the extensive of function to joint channels and collaterals from clearing and activating the channels and collaterals, promoting blood circulation qi-regulating, the angle of scattered stasis detumescence
It is multiple, keep channels and collaterals unobstructed, accelerate scalp and absorb, so can quickly drug effect play, treating both manifestation and root cause of disease makes pain uneasy to recur.
Prioritization scheme one, for treating the External-applicationtraditional traditional Chinese medicinal of arthralgia, including component and component parts by weight
Number is 8 parts of Radix Angelicae Pubescentis, 5 parts of long-nosed pit viper, 6 parts of fresh waxgourd peel, fresh corn palpus 6 parts, 5 parts of agalloch eaglewood, 5 parts of semen litchi, 5 parts of the rhizome of davallia, dragon's blood 5
Part, 8 parts of borneol, 7 parts of peppermint oil, 50 parts of white wine.
Prioritization scheme two, for treating the External-applicationtraditional traditional Chinese medicinal of arthralgia, including component and component parts by weight
Number is 7 parts of Radix Angelicae Pubescentis, 3 parts of long-nosed pit viper, 4 parts of fresh waxgourd peel, fresh corn palpus 5 parts, 6 parts of agalloch eaglewood, 6 parts of semen litchi, 7 parts of the rhizome of davallia, dragon's blood 7
Part, 6 parts of borneol, 8 parts of peppermint oil, 50 parts of white wine.
Prioritization scheme three, for treating the External-applicationtraditional traditional Chinese medicinal of arthralgia, including component and component parts by weight
Number is 6 parts of Radix Angelicae Pubescentis, 4 parts of long-nosed pit viper, 5 parts of fresh waxgourd peel, fresh corn palpus 4 parts, 4 parts of agalloch eaglewood, 7 parts of semen litchi, 6 parts of the rhizome of davallia, dragon's blood 6
Part, 7 parts of borneol, 6 parts of peppermint oil, 50 parts of white wine.
In three above prioritization scheme, the component amount of wind-damp dispelling cold dispelling and inducing diuresis for removing edema effect is more in prioritization scheme one, right
Long in pain time, the patient of joint crymodynia has targetedly therapeutic effect.The component amount of effect of invigorating blood circulation in prioritization scheme two
It is relatively large, it is more applicable with green patient of becoming silted up for pain.Prioritization scheme three is suitble to the patient of generality arthralgia.
It is to be illustrated to the preparation method of the Chinese medicine composition of above scheme below, includes the following steps：
Step 1: white wine is poured out after using 15~20d of soaking in Chinese liquor long-nosed pit viper；Radix Angelicae Pubescentis, agalloch eaglewood and the rhizome of davallia are mixed
Afterwards, after carrying out 20~30d of immersion using the white wine poured out, the taking-up of Radix Angelicae Pubescentis, agalloch eaglewood and the rhizome of davallia is smashed, mixture is obtained；It is white
Wine volatilizees, and obtains dry residue；
Step 2: semen litchi is smashed, after dragon's blood is diced, must be mixed with fresh waxgourd peel and fresh corn, mixture is ground into
Pulpous state obtains slurry；
Step 3: after mixing by the mixture and residue of the slurry of step 3 and step 2, by borneol, peppermint oil
Addition is stirred mixing again, obtains semi-finished product；
Step 4: being uniformly applied to semi-finished product on gauze using gauze, make semi-finished product package in the gauze.
Using the production method of this programme, white wine first will propose effective component therein after the immersion of long-nosed pit viper, this is just not required to
It is used after crushing long-nosed pit viper, ingredient can be extracted on the one hand convenient for absorbing, on the other hand enable to not deposit in final drug
In long-nosed pit viper powder, quality is fine and smooth.The harder ingredient of quality is also extracted using white wine, this some drugs can also be macerated, be convenient for
It crushes.Pulpous state fine crushing is made, is applied with using gauze package in arthritis sore spot, good permeability, is conducive to absorption enhancement drug effect
It plays.
Specific embodiment
Below by the further details of explanation of specific embodiment：
Table 1 is the component and amounts of components that three embodiments include.
Table 1：
| Embodiment | Embodiment 1 | Embodiment 2 | Embodiment 3 |
| Radix Angelicae Pubescentis | 8kg | 7kg | 6kg |
| Long-nosed pit viper | 5kg | 3kg | 4kg |
| Fresh waxgourd peel | 6kg | 4kg | 5kg |
| Fresh corn palpus | 6kg | 5kg | 4kg |
| Agalloch eaglewood | 5kg | 6kg | 4kg |
| Semen litchi | 5kg | 6kg | 7kg |
| The rhizome of davallia | 5kg | 7kg | 6kg |
| Dragon's blood | 5kg | 7kg | 6kg |
| Borneol | 8kg | 6kg | 7kg |
| Peppermint oil | 7kg | 8kg | 6kg |
| White wine | 50kg | 50kg | 50kg |
Embodiment 4：By taking embodiment 1 as an example, elaborate to the preparation method of the traditional chinese medicine composition of the invention, including following
Step：
Step 1: the dosage according to each component gets all all components ready；Use (spring and summer after 15~20d of soaking in Chinese liquor long-nosed pit viper
15 days, 20 days autumn and winters), white wine is poured out；After Radix Angelicae Pubescentis, agalloch eaglewood and the rhizome of davallia are mixed, impregnated using the white wine poured out
After 20~30d (spring and summer 20 days, 30 days autumn and winters), the taking-up of Radix Angelicae Pubescentis, agalloch eaglewood and the rhizome of davallia is smashed, mixture is obtained；White wine
It volatilizees, obtains dry residue；
Step 2: semen litchi is smashed, after dragon's blood is diced, must be mixed with fresh waxgourd peel and fresh corn, mixture is ground into
Pulpous state obtains slurry；
Step 3: after mixing by the mixture and residue of the slurry of step 3 and step 2, by borneol, peppermint oil
Addition is stirred mixing again, obtains semi-finished product；
Step 4: being uniformly applied to semi-finished product on gauze using gauze, make semi-finished product package in the gauze.
Clinical test：
9 people of arthralgia patient is randomly selected in hospital, respectively three groups, is applied with respectively using in above-described embodiment 1~3
Drug composition, the 7 points of uses of daily evening, 7 points of next morning are removed, statistics patient perceptions to feeling of pain decrease and painless
Time discontinues medication after painless, observes 1 year after drug withdrawal, and whether statistics recurs and recurrence time, the results are shown in Table 2.
Table 2：
It is fast to can be seen that the traditional chinese medicine composition of the invention lenitive time by the statistical result of above-mentioned watch 2, cures institute
Time is short, cures in latter year without recurrence case, is as a result superior to the therapeutic effect of the prior art.
Claims (5)
1. the External-applicationtraditional traditional Chinese medicinal for treating arthralgia, it is characterised in that：Including component and component parts by weight
For 6~8 parts of Radix Angelicae Pubescentis, 3~5 parts of long-nosed pit viper, 4~6 parts of fresh waxgourd peel, fresh corn palpus 4~6 parts, 4~6 parts of agalloch eaglewood, semen litchi 5~7
Part, 5~7 parts of the rhizome of davallia, 5~7 parts of dragon's blood, 6~8 parts of borneol, 6~8 parts of peppermint oil, 50 parts of white wine.
2. according to claim 1 for treating the External-applicationtraditional traditional Chinese medicinal of arthralgia, it is characterised in that：Including group
Divide and the parts by weight of component are 8 parts of Radix Angelicae Pubescentis, 5 parts of long-nosed pit viper, 6 parts of fresh waxgourd peel, fresh corn palpus 6 parts, 5 parts of agalloch eaglewood, semen litchi 5
Part, 5 parts of the rhizome of davallia, 5 parts of dragon's blood, 8 parts of borneol, 7 parts of peppermint oil, 50 parts of white wine.
3. according to claim 1 for treating the External-applicationtraditional traditional Chinese medicinal of arthralgia, it is characterised in that：Including group
Divide and the parts by weight of component are 7 parts of Radix Angelicae Pubescentis, 3 parts of long-nosed pit viper, 4 parts of fresh waxgourd peel, fresh corn palpus 5 parts, 6 parts of agalloch eaglewood, semen litchi 6
Part, 7 parts of the rhizome of davallia, 7 parts of dragon's blood, 6 parts of borneol, 8 parts of peppermint oil, 50 parts of white wine.
4. according to claim 1 for treating the External-applicationtraditional traditional Chinese medicinal of arthralgia, it is characterised in that：Including group
Divide and the parts by weight of component are 6 parts of Radix Angelicae Pubescentis, 4 parts of long-nosed pit viper, 5 parts of fresh waxgourd peel, fresh corn palpus 4 parts, 4 parts of agalloch eaglewood, semen litchi 7
Part, 6 parts of the rhizome of davallia, 6 parts of dragon's blood, 7 parts of borneol, 6 parts of peppermint oil, 50 parts of white wine.
5. it is according to any one of claims 1 to 4 for treating the preparation method of the Chinese medicine composition of arthralgia,
It is characterized in that, includes the following steps：
Step 1: white wine is poured out after using 15~20d of soaking in Chinese liquor long-nosed pit viper；After Radix Angelicae Pubescentis, agalloch eaglewood and the rhizome of davallia are mixed, make
After carrying out 20~30d of immersion with the white wine poured out, the taking-up of Radix Angelicae Pubescentis, agalloch eaglewood and the rhizome of davallia is smashed, mixture is obtained；White wine carries out
Volatilization, obtains dry residue；
Step 2: semen litchi is smashed, after dragon's blood is diced, it must be mixed with fresh waxgourd peel and fresh corn, mixture grinds pulp
Obtain slurry；
Step 3: after mixing by the mixture and residue of the slurry of step 3 and step 2, borneol, peppermint oil are added
It is stirred mixing again, obtains semi-finished product；
Step 4: being uniformly applied to semi-finished product on gauze using gauze, make semi-finished product package in the gauze.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810863507.8A CN108815405A (en) | 2018-08-01 | 2018-08-01 | External-applicationtraditional traditional Chinese medicinal and preparation method thereof for treating arthralgia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810863507.8A CN108815405A (en) | 2018-08-01 | 2018-08-01 | External-applicationtraditional traditional Chinese medicinal and preparation method thereof for treating arthralgia |
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| Publication Number | Publication Date |
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| CN108815405A true CN108815405A (en) | 2018-11-16 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101214346A (en) * | 2008-01-11 | 2008-07-09 | 李占山 | Chinese medicine emplastrum for treating pain of vertebrae cervicables lumbar intervertebral disc |
| CN102319330A (en) * | 2011-08-11 | 2012-01-18 | 李涛 | Traditional Chinese medicine cataplasma for treating hyperosteogeny and preparation method thereof |
| CN108175784A (en) * | 2017-12-29 | 2018-06-19 | 何泉宏 | A kind of Chinese medicine composition of rheumatism treating and its medicament preparation method |
-
2018
- 2018-08-01 CN CN201810863507.8A patent/CN108815405A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101214346A (en) * | 2008-01-11 | 2008-07-09 | 李占山 | Chinese medicine emplastrum for treating pain of vertebrae cervicables lumbar intervertebral disc |
| CN102319330A (en) * | 2011-08-11 | 2012-01-18 | 李涛 | Traditional Chinese medicine cataplasma for treating hyperosteogeny and preparation method thereof |
| CN108175784A (en) * | 2017-12-29 | 2018-06-19 | 何泉宏 | A kind of Chinese medicine composition of rheumatism treating and its medicament preparation method |
Non-Patent Citations (1)
| Title |
|---|
| 朱胤龙: "《实用临床中药》", 31 July 2013, 陕西科学技术出版社 * |
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Application publication date: 20181116 |