CN108785548A - 治疗红斑肢痛症中药制剂 - Google Patents

治疗红斑肢痛症中药制剂 Download PDF

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CN108785548A
CN108785548A CN201710292860.0A CN201710292860A CN108785548A CN 108785548 A CN108785548 A CN 108785548A CN 201710292860 A CN201710292860 A CN 201710292860A CN 108785548 A CN108785548 A CN 108785548A
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燕巧红
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Abstract

本发明公开了一种用于治疗红斑肢痛症内服中药制剂，其特征在于，选择的中药原料及重量份分别是：当归尾20克、金银花30克、龙胆草30克、白茅根40克、玄参20克、水牛角20克、延胡索20克、桃仁10克、川芎10克、红花10克、白芍20克、茜草20克、生地黄20克、甘草10克、乳香20克、没药20克、透骨草20克。本发明所选用的原料药材药性效互补，规避了药物之间配伍的相恶、相畏、相杀之选，使药物相须、相使作用显著，具有清热利湿、活血化瘀、益气健脾的功效。内服治疗红斑肢痛症，具有确切疗效。

Description

治疗红斑肢痛症中药制剂
技术领域
本发明涉及中药领域，具体涉及一种治疗红斑肢痛症中药制剂，用于治疗红斑肢痛症内服中药制剂，具有清热利湿、活血化瘀、益气健脾的功效。
背景技术
红斑性肢痛症是一种原因不明的肢端远端皮肤阵发性皮温升高，皮肤潮红、肿胀，并产生剧烈灼热痛为特征的一种植物神经系统疾病。环境温度升高可诱发或加剧疼痛；温度降低可使疼痛缓解。任何年龄均可起病，本病多见于20～40岁青壮年，男性多于女性。起病可急可缓，进展缓慢。多从双侧肢端起病，以双足多见，少数患者可仅见于单侧。表现为足趾、足底、手指和手掌发红、动脉搏动增强，患处皮肤阵发性温度升高、潮红、肿胀和难以忍受的烧灼样疼痛。疼痛为阵发性，可持续数分钟、数小时或数日，以夜间明显且发作次数较多。受热、环境温度升高、行动、肢端下垂、对患肢的抚摸或长时间站立均可导致临床发作或症状加剧。患肢暴露于冷空气或浸泡于冷水中，静卧休息或者将患肢抬高时，可使疼痛减轻或缓解。因此患者喜欢在温度较低的环境里，不愿穿袜或戴手套，而且不愿将四肢放于被内，并且惧怕医生检查。体检可见患处皮肤潮红，压之红色可暂时消失，温度升高，血管扩张，轻度肿胀，足背动脉与胫后动脉搏动正常。在发作间期，患处皮温多低于对侧皮肤。反复发作者可见皮肤与指甲变厚，肌肉萎缩，感觉减退。极少数严重患者可因营养障碍而出现溃疡或坏疽。病程长及（或）病情重者症状不仅限于肢端，可扩及整个下肢及累及上肢。
发明内容
本发明涉及中药领域，具体涉及一种用于治疗红斑肢痛症内服中药制剂，具有清热利湿、活血化瘀、益气健脾的功效。内服，可以用于红斑肢痛症治疗，具有确切疗效。
为实现上述目的本发明采用了如下的技术方案：本发明所述中药制剂选择的药材及重量份分别是：当归尾20克、金银花30克、龙胆草30克、白茅根40克、玄参20克、水牛角20克、延胡索20克、桃仁10克、川芎10克、红花10克、白芍20克、茜草20克、生地黄20克、甘草10克、乳香20克、没药20克、透骨草20克。
本发明选择的中药原料中：当归尾：功效：活血祛瘀。应用：经闭不通及瘀血积滞肿痛的病症。
金银花：【性味归经】味甘；寒。归肺；胃经。【功效主治】清热解毒。温病发热；热毒血痢；痈肿疔疮；喉痹及多种感染性疾病。
龙胆草：具有清热、泻肝、定惊之功效。《本草纲目》记载：“性味苦，涩，大寒，无毒。主治骨间寒热、惊病邪气，继绝伤，定五脏，杀虫毒。功能主治：清热燥湿，泻肝胆火。用于湿热黄疸，阴肿阴痒，带下，强中，湿疹瘙痒，目赤，耳聋，胁痛，口苦，惊风抽搐。
白茅根：性味：味甘苦，性寒，无毒；主治：凉血止血，清热解毒。用于吐血，尿血，热淋，水肿，黄疸，小便不利，热病烦渴，胃热呕哕，咳嗽；脾胃虚寒，溲多不渴者忌服。
玄参：【性味归经】： 味甘、苦、咸； 性微寒。归肺，胃，肾经。【功效】：清热凉血，泻火解毒，滋阴。主治：温热病和营血、身热、烦渴、舌绛、发斑、骨蒸劳嗽、虚烦不寤、津伤便秘、目涩昏花、咽喉喉肿痛、瘰疬痰核、痈疽疮毒。
水牛角：性味：苦，寒。归经：归心、肝经。功效：清热凉血，解毒，定惊。主治：用于温病高热，神昏谵语，发斑发疹，吐血衄血，惊风，癫狂。
延胡索：功能主治：活血，散瘀，理气，止痛。治心腹腰膝诸痛，月经不调，症瘕，崩中，产后血晕，恶露不尽，跌打损伤。
桃仁：【性味归经】苦、甘，平。归心、肝、大肠经。【功能主治】活血祛瘀，润肠通便，止咳平喘。用于经闭，痛经，癓瘕痞块，跌扑损伤，肠燥便秘。
川芎：味辛，性温。归肝、胆、心包经。【 功能与主治】活血行气，祛风止痛。用于安抚神经，正头风头痛，症瘕腹痛，胸胁刺痛，跌扑肿痛，头痛，风湿痹痛。
红花：【化学成分】含红花甙、新红花甙、红花醌甙、红花多糖、棕榈酸、肉桂酸、月桂酸。【性味】 性温，味辛。【功能主治】 活血通经，散淤止痛，用于闭经，痛经，恶露不行，症瘕痞块，跌扑损伤，疮疡肿痛。
白芍：化学成分：芍药甙、牡丹酚、芍药花甙，尚含苯甲酸、挥发油、脂肪油、树脂、鞣质、糖、淀粉、粘液质、蛋白质、β－谷甾醇和三萜类等。药性功效：白芍性凉，味苦酸，微寒，具有补血养血、平抑肝阳、柔肝止痛、敛阴止汗等功效，适用于阴虚发热、月经不调、胸腹胁肋疼痛、四肢挛急，泻痢腹痛、自汗盗汗、崩漏、带下等症。芍药甙有抗菌、解热、抗炎、增加冠状动脉流量、改善心肌营养血流、扩张血管、对抗急性心肌缺血、抑制血小板聚集、镇静、镇痛、解痉、抗溃疡、调节血糖的作用。白芍煎剂能抑制痢疾杆菌、肺炎链球菌、大肠杆菌、伤寒杆菌、溶血性链球菌、绿脓杆菌等。
茜草：【功能主治】凉血，止血，祛瘀，通经，镇咳，祛痰。用于吐血，衄血，崩漏，外伤出血，经闭瘀阻，关节痹痛，跌扑肿痛。现代医学临床研究：可以治疗出血性疾患，慢性气管炎，慢性腹泻，风湿性关节炎，治疗软组织损伤，治疗白细胞减少症。
生地黄：味甘、苦， 性寒．入心、肝、肾经。【功 效】清热生津滋阴，养血。【主 治】治阴虚发热，消渴，吐血，衄血，血崩，月经不调，胎动不安，阴伤便秘。清热凉血，养阴，生津；用于热病烦渴、发斑发疹、阴虚内热、吐血、衄血、糖尿病、传染性肝炎。
甘草：性平，味甘。功能主治：补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性，在中医上，甘草补脾益气，止咳润肺，缓急解毒，调和百药。
乳香：【性味归经】辛苦，温。入心、肝、脾经。【药理作用】本品有较显著的镇痛作用．以乳香为首味药的子宫丸比多种抗菌素有更强烈的抑菌作用, 且能有效地杀灭滴虫．调气活血，定痛，追毒。【功 效】治气血凝滞、心腹疼痛，痈疮肿毒，跌打损伤，痛经，产后瘀血刺痛。
没药：性味：苦，辛，平。入肝、脾、心、肾经。【功 效】：散血去瘀，消肿定痛。主治：湿寒性或黏液质性疾病，如湿寒性关节疼痛，坐骨神经痛，口腔疼痛，咽喉疼痛，寒性咳嗽，湿性痰多，支气管扩张，湿疹脓疮，月经不调，小便不利。
透骨草：【功用主治】：祛风湿，活血，舒筋，止痛。治风湿痛，闪挫伤，无名肿毒，阴囊湿疹。《东北常用中草药手册》：舒筋活血，祛风止痛。治腰腿疼痛，大骨节病关节痛，筋骨麻木，扭挫伤，闪腰岔气。
本发明所选用的原料药材药性效互补，规避了药物之间配伍的相恶、相畏、相杀之选，使药物相须、相使作用显著，具有提高免疫力，清热利湿、活血化瘀、益气健脾的功效。内服治疗红斑肢痛症，具有确切疗效。
利用本发明所述用于治疗红斑肢痛症内服中药制剂，通过临床应用，取得了意想不到的满意效果；
本发明药物治疗红斑肢痛症临床观察：
1.一般资料
收治门诊患者共45例，年龄20-30岁6例，31-40岁12例，41-50岁13例，50岁以上14例。
2．具体实施病例如下：梁某，男，42岁，2012年6月8日不明原因双足渐红，肿胀，灼热，跳痛，运动后或长期站立后加重，下肢抬高或凉水冲洗、休息后疼痛减轻，也渐加重，6月15日到外地求治，诊断为“脉管炎”，用抗生素治疗，效果不佳。6月20日到我院求治。刻下见：双足肿胀、灼热、疼痛，舌质红，苔薄黄，脉弦大而数。中医诊断：血痹。西医诊断：红斑肢痛症。随投以本发明方剂12剂，日服1剂，早晚分2次温服，空腹开水冲服。随后来诊。患者肢肿胀已经明显减轻，舌质淡，苔薄白，脉沉缓。继服14个疗程，诸症皆除。嘱咐其，继续治疗一疗程巩固疗效。服数剂即愈。
具体实施方式
所述用于治疗红斑肢痛症内服中药制剂，其特征在于，选择的中药原料及重量份分别是：当归尾20克、金银花30克、龙胆草30克、白茅根40克、玄参20克、水牛角20克、延胡索20克、桃仁10克、川芎10克、红花10克、白芍20克、茜草20克、生地黄20克、甘草10克、乳香20克、没药20克、透骨草20克；
制备方法：当归尾20克、金银花30克、龙胆草30克、白茅根40克、玄参20克、水牛角20克、延胡索20克、桃仁10克、川芎10克、红花10克、白芍20克、茜草20克、生地黄20克、甘草10克、乳香20克、没药20克、透骨草20克；分别制成饮片，经过高压锅蒸煮杀菌50-70分钟，晾干，获得无菌原材料，进行密封包装，获得商品中药制剂饮品。

Claims (2)

1.用于治疗红斑肢痛症内服治疗红斑肢痛症中药制剂制剂，其特征在于，选择的中药原料及重量份分别是：当归尾20克、金银花30克、龙胆草30克、白茅根40克、玄参20克、水牛角20克、延胡索20克、桃仁10克、川芎10克、红花10克、白芍20克、茜草20克、生地黄20克、甘草10克、乳香20克、没药20克、透骨草20克。
2.根据权利要求1所述的治疗红斑肢痛症内服中药制剂，其特征在于：其制备方法为以下步骤：步骤一）称取原料药材：当归尾20克、金银花30克、龙胆草30克、白茅根40克、玄参20克、水牛角20克、延胡索20克、桃仁10克、川芎10克、红花10克、白芍20克、茜草20克、生地黄20克、甘草10克、乳香20克、没药20克、透骨草20克；
步骤二：将所获的饮片，经过高压锅蒸煮杀菌50-70分钟，晾干，获得无菌原材料；
步骤三：将所获的无菌原材料，进行密封包装，获得商品中药制剂饮品。
CN201710292860.0A 2017-04-28 2017-04-28 治疗红斑肢痛症中药制剂 Pending CN108785548A (zh)

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Publication number Priority date Publication date Assignee Title
CN105079360A (zh) * 2015-09-03 2015-11-25 登封市科创商务咨询有限公司 消肿止痛中药酒

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Publication number Priority date Publication date Assignee Title
CN105079360A (zh) * 2015-09-03 2015-11-25 登封市科创商务咨询有限公司 消肿止痛中药酒

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