CN108785472A - A kind of processing method of Pinellia ternata decoction pieces - Google Patents
A kind of processing method of Pinellia ternata decoction pieces Download PDFInfo
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- CN108785472A CN108785472A CN201810757146.9A CN201810757146A CN108785472A CN 108785472 A CN108785472 A CN 108785472A CN 201810757146 A CN201810757146 A CN 201810757146A CN 108785472 A CN108785472 A CN 108785472A
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- pinellia
- tuber
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- filtrate
- decoction pieces
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- 241001522232 Pinellia ternata Species 0.000 title claims abstract description 31
- 238000003672 processing method Methods 0.000 title claims abstract description 13
- 241001522129 Pinellia Species 0.000 claims abstract description 42
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 29
- 238000001125 extrusion Methods 0.000 claims abstract description 16
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 claims abstract description 12
- 235000019441 ethanol Nutrition 0.000 claims abstract description 12
- 241000219784 Sophora Species 0.000 claims abstract description 9
- 235000006886 Zingiber officinale Nutrition 0.000 claims abstract description 9
- 235000008397 ginger Nutrition 0.000 claims abstract description 9
- 239000000706 filtrate Substances 0.000 claims description 47
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 28
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 24
- 238000001914 filtration Methods 0.000 claims description 20
- 238000001035 drying Methods 0.000 claims description 19
- 239000011259 mixed solution Substances 0.000 claims description 10
- 239000000047 product Substances 0.000 claims description 10
- VILCJCGEZXAXTO-UHFFFAOYSA-N 2,2,2-tetramine Chemical compound NCCNCCNCCN VILCJCGEZXAXTO-UHFFFAOYSA-N 0.000 claims description 7
- 239000002994 raw material Substances 0.000 claims description 7
- 239000000243 solution Substances 0.000 claims description 7
- 229960001124 trientine Drugs 0.000 claims description 7
- 229920001661 Chitosan Polymers 0.000 claims description 6
- 239000001509 sodium citrate Substances 0.000 claims description 6
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 6
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims description 5
- 244000303040 Glycyrrhiza glabra Species 0.000 claims description 5
- 239000000284 extract Substances 0.000 claims description 5
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims description 5
- 230000036541 health Effects 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 5
- 235000011477 liquorice Nutrition 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 5
- 238000000465 moulding Methods 0.000 claims description 5
- 235000019640 taste Nutrition 0.000 claims description 5
- 238000007654 immersion Methods 0.000 claims description 2
- 244000273928 Zingiber officinale Species 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 238000002156 mixing Methods 0.000 claims 1
- 231100000419 toxicity Toxicity 0.000 abstract description 10
- 230000001988 toxicity Effects 0.000 abstract description 10
- 241000234314 Zingiber Species 0.000 abstract description 8
- 238000000034 method Methods 0.000 abstract description 8
- 239000003814 drug Substances 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 6
- 230000001413 cellular effect Effects 0.000 abstract description 2
- 230000007423 decrease Effects 0.000 abstract description 2
- 229940079593 drug Drugs 0.000 abstract description 2
- 230000007233 immunological mechanism Effects 0.000 abstract description 2
- 230000035515 penetration Effects 0.000 abstract description 2
- 235000019633 pungent taste Nutrition 0.000 abstract description 2
- 229920006395 saturated elastomer Polymers 0.000 abstract description 2
- 230000004936 stimulating effect Effects 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 description 4
- 230000002588 toxic effect Effects 0.000 description 4
- 230000008569 process Effects 0.000 description 3
- ODINCKMPIJJUCX-UHFFFAOYSA-N Calcium oxide Chemical compound [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 210000000867 larynx Anatomy 0.000 description 2
- 210000003800 pharynx Anatomy 0.000 description 2
- 241000756998 Alismatales Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000004308 accommodation Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000000292 calcium oxide Substances 0.000 description 1
- 235000012255 calcium oxide Nutrition 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 238000013332 literature search Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002777 nucleoside Substances 0.000 description 1
- 125000003835 nucleoside group Chemical group 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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Abstract
The invention discloses a kind of processing methods of Pinellia ternata decoction pieces, belong to Chinese medicine processing technique field.The present invention is by impregnating the tuber of pinellia, bored profit, extrusion are handled to realize the processing of Pinellia ternata decoction pieces.The present invention handles the tuber of pinellia using ethyl alcohol and lauryl sodium sulfate, and solution can be enable largely to penetrate the cellular layer of the tuber of pinellia, further promotes penetration degree of the solution to the tuber of pinellia.Double of Xiali of the present invention carries out bored profit with Radix Glycyrrhizae, ginger and subprostrate sophora, is saturated and dried with processing respectively so that the toxicity of the tuber of pinellia greatly reduces, and becomes the Pinellia ternata decoction pieces that people can utilize.And subprostrate sophora with it is clearing heat and detoxicating, adjust immunologic mechanism the effect of, Radix Glycyrrhizae with coordinating the drug actions of a prescription the effect of, with ginger arrange in pairs or groups make the tuber of pinellia pungent taste become mildly providing safety guarantee from stimulating.After expanding treatment, the toxicity of the tuber of pinellia further decreases or even goes to zero.
Description
Technical field
The invention belongs to Chinese medicine processing technique fields, and in particular to a kind of processing method of Pinellia ternata decoction pieces.
Background technology
The tuber of pinellia (scientific name：Pinellia ternata) also known as ground text, keep field etc., belong to Arales.It is distributed widely in China
The areas such as the Yangtze river basin and northeast, North China.Medicinal plant has eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, raw with the furuncle effect that disappears, beast
It is medical to control synanche Huang.But since ancient times, the tuber of pinellia because its acrid flavour is peppery, numb tongue due to pierce larynx, have the function of " halberd people pharynx ", be considered
" toxic ".Han dynasty Zhang Zhongjing exists《The deficient beautiful letter warp of gold》Described in process the tuber of pinellia " enable water clearly it is sliding to the greatest extent, wash not yet done toxic ".《Book on Chinese herbal medicine
Through focusing》Claim " enable it is sliding to the greatest extent, not your halberd people pharynx can larynx ".The toxicity of the tuber of pinellia is usually removed by the methods of processing to the tuber of pinellia,
But these methods can not often remove the toxicity of the tuber of pinellia, although remove certain toxicity, can introduce new toxic
Metal ion takes in the internal of human body, will produce undesirable reaction.
Through the literature search of existing technologies, China Patent Publication No. CN103316172A, publication date 2013 09
The patent application on the moon 25 discloses a kind of preparation method of Pinellia ternata decoction pieces, and this method picks net impurity, wash by taking the active compound tuber of pinellia
The processing steps such as only, salt system, quick lime process, Radix Glycyrrhizae cooks, is dry realize the processing of Pinellia ternata decoction pieces.Although prepared half
Summer medicine materical crude slice small toxicity, it is easy to use, but prepare Pinellia ternata decoction pieces can introduce new toxic ion, be unfavorable for production and processing and
It is used as medicine.
Invention content
The purpose of the present invention is to provide a kind of effective Pinellia ternata decoction pieces for reducing Toxicity of Rhizoma Pinelliae, not introducing new toxicity considerations
Processing method.
In order to achieve the above object, the present invention is achieved by the following scheme.
A kind of processing method of Pinellia ternata decoction pieces, includes the following steps：
1) the fresh tuber of pinellia is placed in 5~7h of immersion in ethyl alcohol and the mixed solution of lauryl sodium sulfate, it is proper with solution
Good not cross tuber of pinellia tiling 2~3cm of height, taking-up is dried, and 40~60min is stood；The ethyl alcohol and lauryl sodium sulfate
Volume ratio is 4~7:2~3；
2) extracting liquorice health product, the heating of the water of itself and 5~9 times of weight is decocted 2 times, and filtering takes 1/3 Radix Glycyrrhizae filter residue to continue to add
4~6 water decoct times water of amount and decoct once, and filtering merges filtrate twice, obtains filtrate I；By the two taste medicinal material such as ginger and subprostrate sophora
70% absolute ethyl alcohol of 5 times of amounts is added to extract 3 times, filtering obtains filtrate II and filter residue Q, and 2/3 Radix Glycyrrhizae filter residue and filter residue Q is selected to be placed in
In container, the water of 4~6 times of amounts is added to decoct 1 time, filtering discards filter residue, obtains filtrate III；
3) tuber of pinellia of step 1) processing is placed in the mixed solution of filtrate I and filtrate II and carries out 50~70min of bored profit, so
After place it in mixed liquor T and be impregnated with 30min, taking-up is dried, and is drained the water, and it is 5~6mm sheets to cut into thickness, is dried, drying
Temperature is controlled at 85~90 DEG C so that the control of the moisture of the Pinellia ternata decoction pieces after drying 14%~19%, the mixed liquor T by
The raw material composition of following parts by weight：44~49 parts of triethylene tetramine, 47~59 parts of citric acid, 26~34 parts of chitosan, citric acid
41~45 parts of sodium, 88~108 parts of filtrate III；
4) obtained Pinellia ternata decoction pieces in step 3) are passed through into single screw extrusion machine or double screw extruder extrusion,
Then drying and moulding obtains the tuber of pinellia finished product that water content is 7%~11%；The temperature in one area of the extrusion to 6th area is distinguished
It is 120~145 DEG C, 145~170 DEG C, 160~185 DEG C, 185~210 DEG C, 155~180 DEG C, 130~155 DEG C, rate of feeding
30~80g/ minutes, 80~160 revs/min of screw speed, engine speed was controlled in 70~80Hz, and host current control is 145
~150A.
Further, the volume ratio of filtrate I and filtrate II is 3~5 in the step 3):1.2~2.
Preferably, the mixed liquor T in the step 3) is composed of the following raw materials in parts by weight：47 parts of triethylene tetramine,
53 parts of citric acid, 30 parts of chitosan, 43 parts of sodium citrate, 98 parts of filtrate III.
Compared with prior art, advantageous effects of the invention：
1) present invention handles the tuber of pinellia using ethyl alcohol and lauryl sodium sulfate, can enable solution largely
The cellular layer of the tuber of pinellia is penetrated, penetration degree of the solution to the tuber of pinellia is further promoted.
2) double of Xiali carries out bored profit with Radix Glycyrrhizae, ginger and subprostrate sophora, is saturated and dried with processing respectively so that the poison of the tuber of pinellia
Property greatly reduces, and becomes the Pinellia ternata decoction pieces that people can utilize.And subprostrate sophora have it is clearing heat and detoxicating, adjust immunologic mechanism it
Effect, Radix Glycyrrhizae have the effect of coordinating the drug actions of a prescription, are arranged in pairs or groups with ginger so that the pungent taste of the tuber of pinellia becomes mildly providing safety from stimulating
It ensures.After expanding treatment, the toxicity of the tuber of pinellia further decreases or even goes to zero.
Specific implementation mode
Below by specific embodiment, technical scheme of the present invention is further illustrated.It should be appreciated that this hair
Bright embodiment is not limited to the following examples, and accommodation and/or change in any form made for the present invention all will
Fall into protection scope of the present invention.
Embodiment 1
A kind of processing method of Pinellia ternata decoction pieces, includes the following steps：
1) the fresh tuber of pinellia is placed in ethyl alcohol and the mixed solution of lauryl sodium sulfate and impregnates 5h, do not had just with solution
Tuber of pinellia tiling height 2cm is crossed, taking-up is dried, and 40min is stood；The volume ratio of the ethyl alcohol and lauryl sodium sulfate is 4:2；
2) extracting liquorice health product, the heating of the water of itself and 5 times of weight is decocted 2 times, and filtering takes 1/3 Radix Glycyrrhizae filter residue to continue to add 4 times
The water of amount decocts once, and filtering merges filtrate twice, obtains filtrate I；By the two taste medicinal material such as ginger and subprostrate sophora add 5 times amount
70% absolute ethyl alcohol extracts 3 times, and filtering obtains filtrate II and filter residue Q, selects 2/3 Radix Glycyrrhizae filter residue and filter residue Q to be placed in container, adds 4
The water of amount decocts 1 time again, and filtering discards filter residue, obtains filtrate III；
3) tuber of pinellia of step 1) processing is placed in the mixed solution of filtrate I and filtrate II and carries out 50~70min of bored profit, so
After place it in mixed liquor T and be impregnated with 30min, taking-up is dried, and is drained the water, and it is 5mm sheets, drying, drying temperature to cut into thickness
Degree control is at 85 DEG C so that the moisture of the Pinellia ternata decoction pieces after drying is controlled 14%；Filtrate I and filtrate II in the step 3)
Volume ratio is 3:1.2；The mixed liquor T is composed of the following raw materials in parts by weight：44 parts of triethylene tetramine, 47 parts of citric acid,
26 parts of chitosan, 41 parts of sodium citrate, 88 parts of filtrate III；
4) obtained Pinellia ternata decoction pieces in step 3) are passed through into single screw extrusion machine or double screw extruder extrusion,
Then drying and moulding obtains the tuber of pinellia finished product that water content is 7%；The temperature in the extrusion one area to 6th area is respectively 120
DEG C, 145 DEG C, 160 DEG C, 185 DEG C, 155 DEG C, 130 DEG C, rate of feeding 30g/ minutes, 80 revs/min of screw speed, engine speed
Control is in 70Hz, and host current control is in 145A.
Embodiment 2
A kind of processing method of Pinellia ternata decoction pieces, includes the following steps：
1) the fresh tuber of pinellia is placed in ethyl alcohol and the mixed solution of lauryl sodium sulfate and impregnates 6h, do not had just with solution
Tuber of pinellia tiling height 63cm is crossed, taking-up is dried, and 50min is stood；The volume ratio of the ethyl alcohol and lauryl sodium sulfate is 5:
2；
2) extracting liquorice health product, the heating of the water of itself and 5~9 times of weight is decocted 2 times, and filtering takes 1/3 Radix Glycyrrhizae filter residue to continue to add
The water of 5 times of amounts decocts once, and filtering merges filtrate twice, obtains filtrate I；By the two taste medicinal material such as ginger and subprostrate sophora add 5 times amount
70% absolute ethyl alcohol extracts 3 times, and filtering obtains filtrate II and filter residue Q, selects 2/3 Radix Glycyrrhizae filter residue and filter residue Q to be placed in container, adds 5
The water of amount decocts 1 time again, and filtering discards filter residue, obtains filtrate III；
3) tuber of pinellia of step 1) processing is placed in the mixed solution of filtrate I and filtrate II and carries out bored profit 60min, then will
It, which is placed in mixed liquor T, is impregnated with 30min, and taking-up is dried, and is drained the water, and it is 6mm sheets, drying, drying temperature control to cut into thickness
System is at 88 DEG C so that the moisture of the Pinellia ternata decoction pieces after drying is controlled 17%；The volume of filtrate I and filtrate II in the step 3)
Than being 4:1.8；The mixed liquor T is composed of the following raw materials in parts by weight：47 parts of triethylene tetramine, 53 parts of citric acid, shell are poly-
30 parts of sugar, 43 parts of sodium citrate, 98 parts of filtrate III；
4) obtained Pinellia ternata decoction pieces in step 3) are passed through into single screw extrusion machine or double screw extruder extrusion,
Then drying and moulding obtains the tuber of pinellia finished product that water content is 8%；The temperature in the extrusion one area to 6th area is respectively 135
DEG C, 160 DEG C, 175 DEG C, 190 DEG C, 165 DEG C, 140 DEG C, rate of feeding 55g/ minutes, 120 revs/min of screw speed, engine speed
Control is in 75Hz, and host current control is in 148A.
Embodiment 3
A kind of processing method of Pinellia ternata decoction pieces, includes the following steps：
1) the fresh tuber of pinellia is placed in ethyl alcohol and the mixed solution of lauryl sodium sulfate and impregnates 7h, do not had just with solution
Tuber of pinellia tiling height 3cm is crossed, taking-up is dried, and 60min is stood；The volume ratio of the ethyl alcohol and lauryl sodium sulfate is 7:3；
2) extracting liquorice health product, the heating of the water of itself and 9 times of weight is decocted 2 times, and filtering takes 1/3 Radix Glycyrrhizae filter residue to continue to add 6 times
The water of amount decocts once, and filtering merges filtrate twice, obtains filtrate I；By the two taste medicinal material such as ginger and subprostrate sophora add 5 times amount
70% absolute ethyl alcohol extracts 3 times, and filtering obtains filtrate II and filter residue Q, selects 2/3 Radix Glycyrrhizae filter residue and filter residue Q to be placed in container, adds 6
The water of amount decocts 1 time again, and filtering discards filter residue, obtains filtrate III；
3) tuber of pinellia of step 1) processing is placed in the mixed solution of filtrate I and filtrate II and carries out bored profit 70min, then will
It, which is placed in mixed liquor T, is impregnated with 30min, and taking-up is dried, and is drained the water, and it is 6mm sheets, drying, drying temperature control to cut into thickness
System is at 90 DEG C so that the moisture of the Pinellia ternata decoction pieces after drying is controlled 19%；The volume of filtrate I and filtrate II in the step 3)
Than being 5:2；The mixed liquor T is composed of the following raw materials in parts by weight：49 parts of triethylene tetramine, 59 parts of citric acid, chitosan
34 parts, 45 parts of sodium citrate, 108 parts of filtrate III；
4) obtained Pinellia ternata decoction pieces in step 3) are passed through into single screw extrusion machine or double screw extruder extrusion,
Then drying and moulding obtains the tuber of pinellia finished product that water content is 11%；The temperature in the extrusion one area to 6th area is respectively 145
DEG C, 170 DEG C, 185 DEG C, 210 DEG C, 180 DEG C, 155 DEG C, rate of feeding 80g/ minutes, 160 revs/min of screw speed, engine speed
Control is in 80Hz, and host current control is in 150A.
Experimental example
One, invention technician determines the content of its ingredient, as shown in table 1 by the processing to Pinellia ternata decoction pieces：
Note:Comprehensive score=80 × (total nucleosides ÷ 0.088)+40 × (extract ÷ 15.1) -24
Two, it is as shown in table 2 that expanding treatment its changes in process parameters is carried out after being processed to Pinellia ternata decoction pieces again：
It follows that using the processing method of the present invention, the toxicity of the tuber of pinellia substantially reduces, and realizing the tuber of pinellia can not be direct
The defect utilized.
The present invention can be summarized with others without prejudice to the concrete form of the spirit or essential characteristics of the present invention.No matter from which
From the point of view of a bit, the embodiment above of the invention can only all be considered the description of the invention and cannot limit the present invention, right
Claim indicates the scope of the present invention, therefore, with the comparable meaning and scope of claims of the present invention in it is any
Change, is all considered as being included within Claims scope.
Claims (3)
1. a kind of processing method of Pinellia ternata decoction pieces, it is characterised in that include the following steps：
1) the fresh tuber of pinellia is placed in 5~7h of immersion in ethyl alcohol and the mixed solution of lauryl sodium sulfate, do not had just with solution
Tuber of pinellia tiling 2~3cm of height is crossed, taking-up is dried, and 40~60min is stood；The volume of the ethyl alcohol and lauryl sodium sulfate
Than being 4~7:2~3；
2) extracting liquorice health product, the heating of the water of itself and 5~9 times of weight is decocted 2 times, and filtering takes 1/3 Radix Glycyrrhizae filter residue to continue to add 4~6
Water decocts times water of amount and decocts once, and filtering merges filtrate twice, obtains filtrate I；The two taste medicinal material such as ginger and subprostrate sophora is added 5
70% absolute ethyl alcohol of amount extracts 3 times again, and filtering obtains filtrate II and filter residue Q, and 2/3 Radix Glycyrrhizae filter residue and filter residue Q is selected to be placed in container
In, add the water of 4~6 times of amounts to decoct 1 time, filtering discards filter residue, obtains filtrate III；
3) tuber of pinellia of step 1) processing is placed in the mixed solution of filtrate I and filtrate II and carries out 50~70min of bored profit, then will
It, which is placed in mixed liquor T, is impregnated with 30min, and taking-up is dried, and is drained the water, and it is 5~6mm sheets, drying, drying temperature to cut into thickness
Control is at 85~90 DEG C so that the moisture of the Pinellia ternata decoction pieces after drying is controlled 14%~19%, and the mixed liquor T is by as follows
The raw material of parts by weight forms：44~49 parts of triethylene tetramine, 47~59 parts of citric acid, 26~34 parts of chitosan, sodium citrate 41
~45 parts, 88~108 parts of filtrate III；
4) obtained Pinellia ternata decoction pieces in step 3) are passed through into single screw extrusion machine or double screw extruder extrusion, then
Drying and moulding obtains the tuber of pinellia finished product that water content is 7%~11%；The temperature in the extrusion one area to 6th area is respectively
120~145 DEG C, 145~170 DEG C, 160~185 DEG C, 185~210 DEG C, 155~180 DEG C, 130~155 DEG C, rate of feeding 30
~80g/ minutes, 80~160 revs/min of screw speed, engine speed control in 70~80Hz, host current control 145~
150A。
2. a kind of processing method of Pinellia ternata decoction pieces according to claim 1, it is characterised in that in the step 3) filtrate I with
The volume ratio of filtrate II is 3~5:1.2~2.
3. a kind of processing method of Pinellia ternata decoction pieces according to claim 1, it is characterised in that the mixing in the step 3)
Liquid T is composed of the following raw materials in parts by weight：47 parts of triethylene tetramine, 53 parts of citric acid, 30 parts of chitosan, 43 parts of sodium citrate,
98 parts of filtrate III.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110538303A (en) * | 2019-10-09 | 2019-12-06 | 梁乐 | Harvesting and processing method of curcuma kwangsiensis |
| CN111643587A (en) * | 2020-06-17 | 2020-09-11 | 潜江市潜半夏药业股份有限公司 | Processing method of rhizoma pinellinae praeparata |
| CN113197956A (en) * | 2021-04-30 | 2021-08-03 | 浙江尖峰健康科技有限公司 | Processing technology of pinellia ternata |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110538303A (en) * | 2019-10-09 | 2019-12-06 | 梁乐 | Harvesting and processing method of curcuma kwangsiensis |
| CN111643587A (en) * | 2020-06-17 | 2020-09-11 | 潜江市潜半夏药业股份有限公司 | Processing method of rhizoma pinellinae praeparata |
| CN113197956A (en) * | 2021-04-30 | 2021-08-03 | 浙江尖峰健康科技有限公司 | Processing technology of pinellia ternata |
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Application publication date: 20181113 |