CN108785017B - Rehabilitation training system after oral tumor radiotherapy and using method thereof - Google Patents

Rehabilitation training system after oral tumor radiotherapy and using method thereof Download PDF

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Publication number
CN108785017B
CN108785017B CN201810618492.9A CN201810618492A CN108785017B CN 108785017 B CN108785017 B CN 108785017B CN 201810618492 A CN201810618492 A CN 201810618492A CN 108785017 B CN108785017 B CN 108785017B
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parts
stirring
connecting rod
rack
plate
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CN108785017A (en
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韩霞
菅金波
王峰
王飞鹏
荆航
王惠
姜召峰
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Han Xia
Kan Jinbo
Wang Feng
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61H1/00Apparatus for passive exercising; Vibrating apparatus; Chiropractic devices, e.g. body impacting devices, external devices for briefly extending or aligning unbroken bones
    • A61H1/02Stretching or bending or torsioning apparatus for exercising
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
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    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
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    • A61H2201/16Physical interface with patient
    • A61H2201/1602Physical interface with patient kind of interface, e.g. head rest, knee support or lumbar support
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00Characteristics of apparatus not provided for in the preceding codes
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    • A61H2201/5007Control means thereof computer controlled
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00Characteristics of apparatus not provided for in the preceding codes
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    • A61H2201/5058Sensors or detectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2205/00Devices for specific parts of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A61L2300/104Silver, e.g. silver sulfadiazine
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    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
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    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
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Abstract

A rehabilitation training system after oral tumor radiotherapy and a using method thereof are provided, the rehabilitation training system comprises a shell, an upper biting plate, a lower biting plate and a controller, wherein a first supporting plate and a second supporting plate are arranged in the shell; a bite plate control mechanism is arranged between the first support plate and the inner wall of the shell and comprises a motor, a gear, a first rack and a second rack, the upper end of the first rack is fixed with one end of an upper connecting rod, the other end of the upper connecting rod passes through the second support plate and then is connected with an upper sliding rod, one end of the upper sliding rod extends into the upper connecting rod, and the other end of the upper sliding rod passes through the shell and then is fixed with the upper bite plate; the lower end of the second rack is fixed with one end of a lower connecting rod, the other end of the lower connecting rod penetrates through the second supporting plate and then is connected with a lower sliding rod, one end of the lower sliding rod extends into the lower connecting rod, and the other end of the lower sliding rod penetrates through the shell and then is fixedly connected with the lower biting plate. The invention can realize the automatic work of the upper bite plate and the lower bite plate, is convenient to use and manage, can effectively improve the rehabilitation effect of the oral cavity of a patient and shortens the rehabilitation time.

Description

Rehabilitation training system after oral tumor radiotherapy and using method thereof
Technical Field
The invention relates to the field of medical radiotherapy rehabilitation machinery, in particular to a rehabilitation training system after oral tumor radiotherapy and a using method thereof.
Background
Radiotherapy is a therapy for killing malignant tumor by inhibiting its growth by irradiating it with radiation, and is called radiotherapy for short. The basic principle of radiotherapy is to destroy malignant tumors and preserve normal tissue.
With the development of radiation physics, radiobiology, clinical oncology and various radiotherapy devices, radiotherapy has become three major means of treating malignant tumors along with surgical treatment and chemotherapy. About 70% of patients with malignant tumors require radiation therapy. Of the external beam treatment machines, the most common is the medical electron linac, followed by the cobalt 60 teletherapy machine. In the internal irradiation therapeutic machine, an isotope after-loading machine is mainly used.
Nasopharynx portion and oral cavity radiotherapy belong to the local treatment of tumour radiotherapy, and masticatory muscle and lower jaw joint fibrosis after its radiotherapy to arouse opening the mouth difficulty, its oral cavity is opened and shut naturally and can not reach the state before the radiotherapy, for recovering patient's oral cavity function of opening, should let patient use the gum from thin to thick and insist bite the bite-block of different thickness, or let patient use oral cavity rehabilitation training ware.
For example, the chinese patent (application publication No. CN 104055648A) discloses "an oral rehabilitation training device used after radiotherapy", which comprises a housing, an upper bite plate, a lower bite plate, a bite plate control mechanism and a cheek bulging training mechanism; the bite plate control mechanism comprises a gear, a transmission shaft, a shifting wheel, a rack I and a rack II; the drum cheek training mechanism comprises a seat body, a rubber ball, an airflow pipe, a push-pull pipe and an air bag. The mouth opening training device can realize the closing and opening of the upper biting plate and the lower biting plate through mechanical transmission by shifting the shifting wheel arranged outside the shell, is labor-saving and convenient to operate, is additionally provided with the cheek bulging training mechanism, and can be used for performing cheek bulging training through the rubber balls extending out of two sides when the oral cavity is opened, so that the oral cavity can be quickly restored to be normal when being opened and closed.
The above and existing oral rehabilitation trainers are usually operated manually, and are inconvenient to use; in addition, the upper bite plate and the lower bite plate can only vertically move in a straight line, and the actual opening and closing movement track of the oral cavity of the patient is of a curve structure, so that the change processes of the upper bite plate and the lower bite plate are not consistent, and the oral cavity rehabilitation effect of the patient is influenced; secondly, the immunity of the patient after radiotherapy can be reduced, the existing oral rehabilitation training device needs continuous maintenance, cleaning and sterilization, the effective self-sterilization effect cannot be realized, and hidden dangers exist for the rehabilitation and the safety of the patient.
Disclosure of Invention
The invention provides a rehabilitation training system after oral tumor radiotherapy and a using method thereof, which are used for solving the defects in the prior art.
In order to realize the purpose of the invention, the following technical scheme is adopted:
a rehabilitation training system after oral tumor radiotherapy comprises a shell, an upper bite plate, a lower bite plate and a controller, wherein a first vertical supporting plate and a second vertical supporting plate are arranged in the shell, and are arranged in parallel and fixed with the inner wall of the shell respectively; a bite plate control mechanism is arranged between the first supporting plate and the inner wall of the shell, the bite plate control mechanism comprises a motor, a gear, a first rack and a second rack, a motor shaft is arranged on the motor, the gear is mounted on the motor shaft, the end part of the motor shaft penetrating through the gear is connected with the shell through a bearing, the first rack and the second rack are meshed with the gear, the first rack and the second rack are respectively matched with clamping rails fixedly mounted on opposite surfaces of the shell and the first supporting plate, the first rack and the second rack slide along the clamping rails under the driving of the gear, the side surface of the upper end of the first rack is fixedly connected with one end of a transverse upper connecting rod, the other end of the upper connecting rod penetrates through the second supporting plate and then is connected with an upper sliding rod, one end of the upper sliding rod extends into the upper connecting rod, and; the side face of the lower end of the second rack is fixedly connected with one end of a transverse lower connecting rod, the other end of the lower connecting rod penetrates through the second supporting plate and then is connected with a lower sliding rod, one end of the lower sliding rod extends into the lower connecting rod, and the other end of the lower sliding rod penetrates through the shell and then is fixedly connected with a lower biting plate; the upper connecting rod and the lower connecting rod are of sleeve structures, a transverse power mechanism is mounted in each sleeve structure and comprises a power part, a straight rod and a raised head, a groove is formed in the front end of each raised head, and the end parts of the upper sliding rod and the lower sliding rod are both provided with groovesA clamping groove matched with the raised head is formed, a magnetic induction sheet is arranged in the clamping groove, a magnetic sensing chip is arranged in the groove, the magnetic sensing chip and the magnetic induction sheet are used for acquiring moving data of the upper sliding rod relative to the upper connecting rod and the lower sliding rod relative to the lower connecting rod, a limit baffle is arranged between the power part and the clamping groove, a raised head through hole is formed in the middle of the limit baffle, and the magnetic sensing chip and the motor are electrically connected with the controller; the outer wall of the shell, the first supporting plate and the second supporting plate are respectively provided with a sterilization coating, and the raw materials for preparing the sterilization coating comprise the following components in parts by mass: 28-36 parts of alkyd resin, 70-90 parts of chlorinated rubber, 3-6 parts of lecithin, 8-10 parts of carboxymethyl cellulose, 30-35 parts of oxidized castor oil, 9-13 parts of calcium carbonate powder, 3-5 parts of benzene-terminated polyisobutylene, 6-8 parts of dodecyl alcohol ester, 2-5 parts of dimethyl azodiisobutyrate, Ag-CuO-MnO224-30 parts of composite bactericide, 12-16 parts of graphite fluoride, 5-9 parts of gelatin and 20-40 parts of propylene glycol.
In order to further realize the purpose of the invention, the following technical scheme can be adopted:
the rehabilitation training system after the oral tumor radiotherapy comprises the following raw materials in parts by mass: 28 parts of alkyd resin, 70 parts of chlorinated rubber, 3 parts of lecithin, 8 parts of carboxymethyl cellulose, 30 parts of oxidized castor oil, 9 parts of calcium carbonate powder, 3 parts of benzene-terminated polyisobutylene, 6 parts of dodecyl alcohol ester, 2 parts of dimethyl azodiisobutyrate, and Ag-CuO-MnO224 parts of composite bactericide, 12 parts of graphite fluoride, 5 parts of gelatin and 20 parts of propylene glycol.
The rehabilitation training system after the oral tumor radiotherapy comprises the following raw materials in parts by mass: 32 parts of alkyd resin, 80 parts of chlorinated rubber, 5 parts of lecithin, 9 parts of carboxymethyl cellulose, 32 parts of oxidized castor oil, 11 parts of calcium carbonate powder, 4 parts of benzene-terminated polyisobutylene, 7 parts of dodecyl alcohol ester, 4 parts of dimethyl azodiisobutyrate, and Ag-CuO-MnO227 parts of composite bactericide, 14 parts of graphite fluoride, 7 parts of gelatin and 30 parts of propylene glycol.
The Ag-CuO-MnO system of the rehabilitation training system used after the oral tumor radiotherapy2The preparation method of the composite bactericide comprises:
(1) Weighing copper nitrate and manganese sulfate, adding a proper amount of distilled water, mixing and stirring until the copper nitrate and the manganese sulfate are completely dissolved, then adding a urea solution and a sodium chlorate solution, mixing and stirring uniformly, adding the mixed solution into a high-pressure reaction kettle, heating to 120 ℃, keeping the temperature for 1h, heating to 140 ℃, keeping the temperature for 6h, filtering, washing, drying and grinding to obtain CuO-MnO2A tubular composite material;
(2) mixing diatomite and attapulgite, grinding, sieving with a 200-mesh sieve, adding into an appropriate amount of acid solution, stirring at 60 deg.C for 2 hr, filtering, and washing to obtain mixed powder;
(3) adding distilled water into the mixed powder prepared in the step (2), performing ultrasonic dispersion, adding cobalt nitrate and N-methylpyrrolidone, stirring, dissolving and dispersing uniformly, performing ultrasonic oscillation and stirring for 30min, rapidly injecting a sodium borohydride solution, stirring, dropwise adding a silver nitrate solution into the mixed solution, performing ultrasonic oscillation and stirring for 1h, and adding the CuO-MnO prepared in the step (1)2Stirring the tubular composite material and a proper amount of gelatin at 60 +/-5 ℃ to completely dissolve the tubular composite material and the gelatin to obtain a uniform colloidal mixed material;
(4) sealing and aging the colloidal mixed material prepared in the step (3), adding excessive alcohol into the aged colloidal mixed material, filtering to obtain a gelatin-based sponge, placing the gelatin-based sponge into liquid nitrogen for quick freezing for 3min, roasting at the high temperature of 650 ℃ for 4-6h after freeze drying, cooling to room temperature, and grinding and crushing to obtain a mixed material;
(5) adding the mixed material obtained in the step (4) into an acetone solution, uniformly dispersing, adding sorbic acid, stirring for 1h, filtering and drying to obtain the Ag-CuO-MnO2A composite bactericide.
The rehabilitation training system after the oral tumor radiotherapy is characterized in that the power part is an electric telescopic rod.
A rehabilitation training system after radiation therapy of oral tumors, the power component is a miniature hydraulic cylinder, a hydraulic chamber is arranged in the shell, a miniature hydraulic pump is installed on the hydraulic chamber, and the miniature hydraulic pump is communicated with the miniature hydraulic cylinder and the hydraulic chamber through pipelines.
A rehabilitation training system after radiation therapy of oral tumor, go up and sting the board, sting the board down and be the arc, all be provided with the bellied flexion in outside on last slide bar, the lower slide bar of being connected respectively with last sting the board, sting the board down.
The invention also provides a use method of the rehabilitation training system after the radiation therapy of the oral tumor, which comprises the rehabilitation training system and the use method thereof as follows:
(1) in the initial state, the transverse power mechanism drives the raised head to retract, the upper bite plate and the lower bite plate are in a closed state, and the upper bite plate and the lower bite plate are placed in the oral cavity of a patient and are respectively contacted with the upper and lower gums of the patient;
(2) then, manually operating to open the upper bite plate and the lower bite plate, detecting the change of the position of the magnetic induction sheet by the magnetic sensing chip to obtain the motion data of the upper and lower teethridge of the patient, and storing the motion data into the controller by the magnetic sensing chip to form a motion curve;
(3) the working mode of the motor is set through the controller, and the power component works according to the acquired motion curve, so that the upper biting plate and the lower biting plate can transversely move while opening and closing the oral cavity of the patient, and the oral rehabilitation training is started;
(4) when the oral rehabilitation training is finished, the upper bite plate and the lower bite plate are taken out of the oral cavity of the patient in a closed state.
The use method of the rehabilitation training system after the oral tumor radiotherapy comprises the step (3) that the working mode of the motor comprises the times and the groups of the rehabilitation training formed by the opening and closing of the upper biting plate and the lower biting plate driven by the motor.
The using method of the rehabilitation training system after the oral tumor radiotherapy comprises the steps that the number of times of rehabilitation training is 2-6 times per minute, the number of groups of rehabilitation training is 5-10, and the interval time of each group is 2-5 minutes.
The invention has the beneficial effects that:
1. the upper bite plate and the lower bite plate are respectively fixed at the outer ends of the upper sliding rod and the lower sliding rod, the upper sliding rod is movably connected with the upper connecting rod, the lower sliding rod is movably connected with the lower connecting rod, and a magnetic induction sheet and a magnetic induction chip which are used for acquiring action data are arranged at the positions of the connecting parts. In an initial state, the transverse power mechanism drives the raised head to retract, and the upper bite plate and the lower bite plate are placed in the oral cavity of a patient and are respectively contacted with the upper and lower gums of the patient; then the patient's teethridge and the upper bite plate, the lower bite plate act together, the magnetic sensing chip detects the change of the position of the magnetic induction sheet, obtains the motion data of the patient's upper and lower teethridge, the magnetic sensing chip stores the motion data into the controller to form a motion curve; then the controller sets the working mode of the motor, the power component works according to the acquired motion curve, so that the upper biting plate and the lower biting plate can move transversely while opening and closing the oral cavity of the patient, the motor drives the gear to rotate through the motor shaft and transmits the rotation to the first rack and the second rack which are meshed with the gear, so that the upper connecting rod and the lower connecting rod respectively move up and down relatively, and the oral rehabilitation training is started.
When the device is used, the actual opening and closing movement tracks of the upper bite plate, the lower bite plate and the oral cavity of the patient are all in a curve structure, so that the change processes of the upper bite plate and the lower bite plate are consistent, the oral cavity rehabilitation of the patient after radiotherapy is facilitated, and the use comfort is improved.
2. The invention can realize the automatic work of the upper biting plate and the lower biting plate by arranging the motor, the transverse power mechanism and the controller, is convenient to use and manage, can effectively improve the rehabilitation effect of the oral cavity of a patient, shortens the rehabilitation time, and reduces the labor intensity of medical staff and the like.
3. The sterilization coating is arranged on the outer wall of the shell, the upper biting plate and the lower biting plate, so that the rehabilitation and the use safety of a patient are protected. The bactericidal coating is prepared by using alkyd resin and chlorinated rubber as main materials, and matching graphite fluoride, oxidized castor oil, Ag-CuO-MnO2 composite bactericide and other additives, wherein the formula proportion of the bactericidal coating is obtained, the graphite fluoride, the oxidized castor oil, the alkyd resin and the chlorinated rubber are matched for use, so that the wear resistance, the corrosion resistance and the hardness of the bactericidal coating can be improved, the structure of the oxidized castor oil and the structures of the alkyd resin and the chlorinated rubber are mutually penetrated and permeated to form an interpenetrating network structure, the Ag-CuO-MnO2 composite bactericide and calcium carbonate powder are penetrated in the bactericidal coating, the dispersion is uniform and difficult to separate out, the drying and the solidification of the coating are fast, the film forming is uniform, the structure of the coating is compact, the coating can be firmly attached to the surface of a coated object.
4. The Ag-CuO-MnO2 composite bactericide in the bactericidal coating has a continuous carbon layer with a porous structure, can be better crosslinked with other materials in the coating after modification, is uniformly distributed in an interpenetrating network structure of the coating and is not easy to separate out, the bactericidal effect is also completed under the mutual synergistic effect of four materials, namely a nano silver hollow sphere, a CuO-MnO2 tubular composite material, diatomite and attapulgite, the composite bactericide has a plurality of porous structures with different sizes and is easier to adsorb bacteria, moreover, the silver in the Ag-CuO-MnO2 composite bactericide is of a hollow sphere structure, the generated nano silver hollow sphere is coated on the diatomite and the attapulgite, the CuO is coated on the tubular MnO2, and the nano silver hollow sphere and the CuO are communicated with each other, so that the bactericidal and antibacterial effects can be better promoted; firstly, the composite bactericide has a plurality of porous structures with different sizes, which can efficiently and quickly adsorb bacteria, the nano-silver hollow spheres are distributed on the surfaces of diatomite, attapulgite and CuO-MnO2 tubular composite materials, the nano-silver hollow spheres and the nano-CuO are communicated with each other, the particle diameters of the nano-silver hollow spheres and the nano-CuO are small and uniformly distributed, the nano-silver hollow spheres can be quickly adsorbed on the surface of a bacterial cell membrane to block the normal substance transmission of the bacteria and destroy the physiological function of the bacteria, the nano-CuO penetrates through the bacterial cell membrane to enter the inside of the bacteria to inhibit the growth of the bacteria, and the nano-silver hollow spheres, the CuO-2 tubular composite materials, the diatomite and the attapulgite are mutually matched to act, so that the.
5. The bactericidal coating disclosed by the invention is compact in film structure, can be firmly attached to the surface of an object to be coated, is strong in adhesive force, has better wear resistance and corrosion resistance, also has good pollution resistance and bactericidal and bacteriostatic properties, breaks through the defects of the traditional mechanical coating, can kill bacteria, inhibit the growth of bacteria, is safe and environment-friendly, provides a safer, healthier and cleaner environment for equipment users, and can be widely applied to the fields of medical equipment, toys for children, electrical appliances, health-care and fitness equipment, other common equipment and the like.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a top view of FIG. 1;
FIG. 3 is an enlarged schematic view of the upper link and upper slide bar of FIG. 1;
FIG. 4 is a schematic view of the internal structure of the lateral force mechanism of FIG. 3;
FIG. 5 is another state reference diagram of FIG. 4;
FIG. 6 is an enlarged sectional view taken along line A-A of FIG. 5;
fig. 7 is an enlarged sectional view taken along line B-B of fig. 5.
Reference numerals: 1-shell, 2-upper snap plate, 3-lower snap plate, 4-controller, 5-first support plate, 6-second support plate, 7-motor, 8-gear, 9-first rack, 10-second rack, 11-motor shaft, 12-clamping rail, 13-upper connecting rod, 14-upper sliding rod, 15-lower connecting rod, 16-lower sliding rod, 17-power part, 18-straight rod, 19-raised head, 20-groove, 21-clamping groove, 22-magnetic induction sheet, 23-magnetic induction chip, 24-hydraulic chamber, 25-micro hydraulic pump, 26-pipeline, 27-bending part, 28-battery, 29-limit baffle and 30-through hole.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
As shown in fig. 1 and fig. 2, the rehabilitation training system after oral tumor radiotherapy disclosed in this embodiment includes a housing 1, an upper bite plate 2, a lower bite plate 3 and a controller 4, wherein a first support plate 5 and a second support plate 6 are vertically installed in the housing 1, and the first support plate 5 and the second support plate 6 are arranged in parallel and fixed to the inner wall of the housing 1 respectively; a biting plate control mechanism is arranged between the first supporting plate 5 and the inner wall of the shell 1, the biting plate control mechanism comprises a motor 7, a gear 8, a first rack 9 and a second rack 10, a motor shaft 11 is arranged on the motor 7, the gear 8 is arranged on the motor shaft 11, the end part of the motor shaft 11 penetrating through the gear 8 is connected with the shell 1 through a bearing, the first rack 9, the second rack 10 is meshed with the gear 8, the first rack 9 and the second rack 10 are respectively matched with a clamping rail 12 fixedly arranged on the opposite surfaces of the shell 1 and the first supporting plate 5, the first rack 9 and the second rack 10 can slide along the clamping rail 12, the side surface of the upper end of the first rack 9 is fixedly connected with one end of a transverse upper connecting rod 13, the other end of the upper connecting rod 13 penetrates through the second supporting plate 6 and then is connected with an upper sliding rod 14, one end of the upper sliding rod 14 extends into the upper connecting rod 13, and the other end of the upper sliding rod 14 penetrates through the shell 1 and then is fixed with the upper biting plate 2; the side face of the lower end of the second rack 10 is fixedly connected with one end of a transverse lower connecting rod 15, the other end of the lower connecting rod 15 penetrates through the second supporting plate 6 and then is connected with a lower sliding rod 16, one end of the lower sliding rod 16 extends into the lower connecting rod 15, and the other end of the lower sliding rod 16 penetrates through the shell 1 and then is fixedly connected with the lower biting plate 3; the upper connecting rod 13 and the lower connecting rod 15 at the connecting part of the upper connecting rod 13 and the upper sliding rod 14 and the lower connecting rod 15 and the lower sliding rod 16 are both in a sleeve structure, and a transverse power mechanism is arranged in the sleeve structure.
As shown in fig. 1, the arc lines shown above and below the upper bite plate 2 and the lower bite plate 3 are the actual opening and closing movement tracks of the oral cavity of the patient.
The shell 1 is divided into three cavities through the first supporting plate 5 and the second supporting plate 6, wherein the biting plate control mechanism is located in the cavity formed by the first supporting plate 5 and the side wall of the shell 1 in a surrounding mode, the clamping rails 12, the first rack 9, the second rack 10 and other components are convenient to mount, and vertical or transverse moving auxiliary guide rails can be arranged between the upper connecting rod 13, the lower connecting rod 15 and the second supporting plate 6 so as to improve the temperature performance of actions of the upper biting plate 2 and the lower biting plate 3.
As shown in fig. 3, 4 and 5, the transverse power mechanism comprises a power part 17, a straight rod 18 and a raised head 19, a groove 20 is formed at the front end of the raised head 19, and a clamping groove 21 matched with the raised head 19 is formed at each of the ends of the upper slide bar 14 and the lower slide bar 16.
As shown in fig. 6 and 7, a magnetic induction sheet 22 is installed in the card slot 21, a magnetic sensing chip 23 is installed in the groove 20, the magnetic sensing chip 23 and the magnetic induction sheet 22 are used for acquiring movement data of the upper sliding rod 14 and the lower sliding rod 16 relative to the upper connecting rod 13 and the lower connecting rod 15, a limit baffle 29 is arranged between the power component 17 and the card slot 21, a raised head 19 is arranged in the middle of the limit baffle 29 through a hole 30, and the magnetic sensing chip 23 and the motor 7 are electrically connected with the controller 4; the outer wall of the shell 1, the upper biting plate 2 and the lower biting plate 3 are all provided with sterilization coatings.
Specifically, the upper bite plate 2 and the lower bite plate 3 in this embodiment are respectively fixed at the outer ends of the upper slide bar 14 and the lower slide bar 16, because the upper slide bar 14 and the upper link 13, and the lower slide bar 16 and the lower link 15 are movably connected, and the magnetic sensing sheet 22 and the magnetic sensing chip 23 for acquiring motion data are arranged at the position of the connecting portion, and are stored in the controller 4 to automatically control the rehabilitation training of the oral cavity of the patient.
When in use, in an initial state, the transverse power mechanism drives the raised head 19 to retract, and the upper bite plate 2 and the lower bite plate 3 are placed in the oral cavity of a patient and are respectively contacted with the upper and lower gums of the patient; then the patient's teethridge moves together with the upper bite plate 2 and the lower bite plate 3, the magnetic sensing chip 23 detects the change of the position of the magnetic sensing sheet 22 to obtain the motion data of the patient's upper and lower teethridge, and the magnetic sensing chip 23 stores the motion data into the controller 4 to form a motion curve; then the controller 4 sets the working mode of the motor 7, the power part 17 works according to the acquired motion curve, so that the upper biting plate 2 and the lower biting plate 3 can realize transverse movement while opening and closing the oral cavity of the patient, the motor 7 drives the gear 8 to rotate through the motor shaft 11, and the gear 8 is transmitted to the first rack 9 and the second rack 10 meshed with the gear 8, so that the upper connecting rod 13 and the lower connecting rod 15 respectively move up and down relatively, and the oral rehabilitation training is started.
The actual opening and closing movement tracks of the upper bite plate 2, the lower bite plate 3 and the oral cavity of the patient are of a curve structure, so that the change processes of the upper bite plate and the lower bite plate are consistent, the oral cavity rehabilitation of the patient after radiotherapy is facilitated, and the use comfort is improved.
A rechargeable battery 28 may also be provided within the housing 1 to power the motor 7 and controller 4, and the operating voltage should preferably be a safe voltage below 24V due to direct contact with the patient. The controller 4 adopts a PHILIIS 51LPC series single chip microcomputer, and is embedded with functions of power failure detection, simulation, an on-chip RC oscillator and the like based on an 80C51 kernel, so that the controller 4 can meet performance requirements of high integration level, low cost, low power consumption and the like. The magnetic induction sheet 22 and the magnetic sensing chip 23 are arranged in a space with a small interval, have good measurement sensitivity and precision, realize the detection and storage of the displacement of the upper sliding rod 14 and the lower sliding rod 16 by utilizing the change of a magnetic field, and transmit the displacement to the controller 4 to realize the control of the power component 17 during the rehabilitation training.
Further, this embodiment all is equipped with the bactericidal coating in 1 outer wall of casing, first backup pad, the second backup pad to the protection patient is recovered and safe in utilization. The raw materials for preparing the bactericidal coating comprise the following components in parts by mass: 28-36 parts of alkyd resin, 70-90 parts of chlorinated rubber, 3-6 parts of lecithin, 8-10 parts of carboxymethyl cellulose, 30-35 parts of oxidized castor oil, 9-13 parts of calcium carbonate powder, 3-5 parts of benzene-terminated polyisobutylene, 6-8 parts of dodecyl alcohol ester, 2-5 parts of dimethyl azodiisobutyrate, Ag-CuO-MnO224-30 parts of composite bactericide, 12-16 parts of graphite fluoride, 5-9 parts of gelatin and 20-40 parts of propylene glycol.
Example 1
The raw materials for preparing the bactericidal coating comprise the following components in parts by mass: 28 parts of alkyd resin, 70 parts of chlorinated rubber, 3 parts of lecithin, 8 parts of carboxymethyl cellulose, 30 parts of oxidized castor oil, 9 parts of calcium carbonate powder, 3 parts of benzene-terminated polyisobutylene, 6 parts of dodecyl alcohol ester, 2 parts of dimethyl azodiisobutyrate, 24 parts of Ag-CuO-MnO2 composite bactericide, 12 parts of graphite fluoride, 5 parts of gelatin and 20 parts of propylene glycol.
The preparation method of the Ag-CuO-MnO2 composite bactericide comprises the following steps: weighing copper nitrate and manganese sulfate, adding a proper amount of distilled water, mixing and stirring until the copper nitrate and the manganese sulfate are completely dissolved, then adding a urea solution and a sodium chlorate solution, mixing and stirring uniformly, adding the mixed solution into a high-pressure reaction kettle, heating to 120 ℃, keeping the temperature for 1h, heating to 140 ℃, keeping the temperature for 6h, filtering, washing, drying and grinding to obtain a CuO-MnO2 tubular composite material; mixing diatomite and attapulgite, grinding, sieving with a 200-mesh sieve, adding into an appropriate amount of acid solution, stirring at 60 deg.C for 2 hr, filtering, and washing to obtain mixed powder; adding distilled water into the mixed powder, performing ultrasonic dispersion, adding cobalt nitrate and N-methyl pyrrolidone, stirring, dissolving and dispersing uniformly, performing ultrasonic oscillation and stirring for 30min, rapidly injecting a sodium borohydride solution, stirring, dropwise adding a silver nitrate solution into the mixed solution, performing ultrasonic oscillation and stirring for 1h, adding a CuO-MnO2 tubular composite material and a proper amount of gelatin, and stirring at 60 +/-5 ℃ to completely dissolve the CuO-MnO2 tubular composite material and the gelatin to obtain a uniform colloidal mixed material.
Sealing and aging the colloidal mixed material for 6h, then adding excessive alcohol into the aged colloidal mixed material, filtering to obtain a gelatin-based sponge, placing the gelatin-based sponge into liquid nitrogen for quick freezing for 3min, freeze-drying, roasting at the high temperature of 500 ℃ for 6h, cooling to room temperature, grinding and crushing to obtain a mixed material; adding the mixed material into an acetone solution, uniformly dispersing, adding sorbic acid, stirring for 1h, filtering and drying to obtain the Ag-CuO-MnO2 composite bactericide, wherein in the prepared Ag-CuO-MnO2 composite bactericide, the mass ratio of Ag to CuO to MnO2 to diatomite to attapulgite is 2:1:0.8:6: 8.
The preparation method of the bactericidal coating comprises the following steps:
(1) ultrasonically stirring and uniformly mixing oxidized castor oil, graphite fluoride and 1/3 parts by weight of benzene-terminated polyisobutylene to obtain a mixed material A;
(2) putting alkyd resin, chlorinated rubber, propylene glycol and lecithin into a reaction kettle, and mechanically stirring until the alkyd resin, the chlorinated rubber, the propylene glycol and the lecithin are completely and uniformly mixed to obtain a mixed material B;
(3) heating the mixed material B in the reaction kettle to 70 ℃, adding dimethyl azodiisobutyrate and the residual 2/3 parts by weight of benzene-terminated polyisobutylene, mechanically stirring for 30min, adding the Ag-CuO-MnO2 composite bactericide and calcium carbonate powder, and mechanically stirring for 6h to obtain a mixed material C;
(4) heating the mixed material C in the reaction kettle to 120 ℃, dropwise adding the mixed material A under the condition of mechanical stirring, and after dropwise adding is finished, continuously stirring for 6 hours at 120 ℃ to obtain a mixed material D;
(5) and cooling the mixed material D to 50 ℃, adding the carboxymethyl cellulose, the dodecyl alcohol ester and the gelatin, mechanically stirring until the carboxymethyl cellulose, the dodecyl alcohol ester and the gelatin are completely dissolved and uniformly dispersed, and cooling to room temperature to obtain the bactericidal coating.
Example 2
The raw materials for preparing the bactericidal coating comprise the following components in parts by mass: 32 parts of alkyd resin, 80 parts of chlorinated rubber, 5 parts of lecithin, 9 parts of carboxymethyl cellulose, 32 parts of oxidized castor oil, 11 parts of calcium carbonate powder, 4 parts of benzene-terminated polyisobutylene, 7 parts of dodecyl alcohol ester, 4 parts of dimethyl azodiisobutyrate, 27 parts of Ag-CuO-MnO2 composite bactericide, 14 parts of graphite fluoride, 7 parts of gelatin and 30 parts of propylene glycol.
The preparation method of the Ag-CuO-MnO2 composite bactericide comprises the following steps: weighing copper nitrate and manganese sulfate, adding a proper amount of distilled water, mixing and stirring until the copper nitrate and the manganese sulfate are completely dissolved, then adding a urea solution and a sodium chlorate solution, mixing and stirring uniformly, adding the mixed solution into a high-pressure reaction kettle, heating to 120 ℃ at the speed of 6-8 ℃/min, preserving heat for 1h, heating to 140 ℃ and preserving heat for 6h, filtering, washing, drying and grinding to obtain a CuO-MnO2 tubular composite material; mixing diatomite and attapulgite, grinding, sieving with a 200-mesh sieve, adding into an appropriate amount of acid solution, stirring at 60 deg.C for 2 hr, filtering, and washing to obtain mixed powder; adding distilled water into the mixed powder, performing ultrasonic dispersion, adding cobalt nitrate and N-methyl pyrrolidone, stirring, dissolving and dispersing uniformly, performing ultrasonic oscillation and stirring for 30min, rapidly injecting a sodium borohydride solution, dropwise adding a silver nitrate solution into the mixed solution, performing ultrasonic oscillation and stirring for 1h, adding a CuO-MnO2 tubular composite material and a proper amount of gelatin, and stirring at 60 +/-5 ℃ to completely dissolve the CuO-MnO2 tubular composite material and the gelatin to obtain a uniform colloidal mixed material; sealing and aging the colloidal mixed material for 8h, then adding excessive alcohol into the aged colloidal mixed material, filtering to obtain a gelatin-based sponge, placing the gelatin-based sponge into liquid nitrogen for quick freezing for 3min, freeze-drying, roasting at the high temperature of 500 ℃ for 6h, cooling to room temperature, grinding and crushing to obtain a mixed material; adding the mixed material into an acetone solution, uniformly dispersing, adding sorbic acid, stirring for 1h, filtering and drying to obtain the Ag-CuO-MnO2 composite bactericide, wherein in the prepared Ag-CuO-MnO2 composite bactericide, the mass ratio of Ag to CuO to MnO2 to diatomite to attapulgite is 3:1.5:0.8:10: 8.
The preparation method of the bactericidal coating comprises the following steps:
(1) ultrasonically stirring and uniformly mixing oxidized castor oil, graphite fluoride and 1/3 parts by weight of benzene-terminated polyisobutylene to obtain a mixed material A;
(2) putting alkyd resin, chlorinated rubber, propylene glycol and lecithin into a reaction kettle, and mechanically stirring until the alkyd resin, the chlorinated rubber, the propylene glycol and the lecithin are completely and uniformly mixed to obtain a mixed material B;
(3) heating the mixed material B in the reaction kettle to 70 ℃, adding dimethyl azodiisobutyrate and the residual 2/3 parts by weight of benzene-terminated polyisobutylene, mechanically stirring for 30min, adding the Ag-CuO-MnO2 composite bactericide and calcium carbonate powder, and mechanically stirring for 10h to obtain a mixed material C;
(4) heating the mixed material C in the reaction kettle to 120 ℃, dropwise adding the mixed material A under the condition of mechanical stirring, and after dropwise adding is finished, continuously stirring for 8 hours at 120 ℃ to obtain a mixed material D;
(5) and cooling the mixed material D to 50 ℃, adding the carboxymethyl cellulose, the dodecyl alcohol ester and the gelatin, mechanically stirring until the carboxymethyl cellulose, the dodecyl alcohol ester and the gelatin are completely dissolved and uniformly dispersed, and cooling to room temperature to obtain the bactericidal coating.
Example 3
The raw materials for preparing the bactericidal coating comprise the following components in parts by mass: 36 parts of alkyd resin, 90 parts of chlorinated rubber, 6 parts of lecithin, 10 parts of carboxymethyl cellulose, 35 parts of oxidized castor oil, 13 parts of calcium carbonate powder, 5 parts of benzene-terminated polyisobutylene, 8 parts of dodecyl alcohol ester, 5 parts of dimethyl azodiisobutyrate, 30 parts of Ag-CuO-MnO2 composite bactericide, 16 parts of graphite fluoride, 9 parts of gelatin and 40 parts of propylene glycol.
The preparation method of the Ag-CuO-MnO2 composite bactericide comprises the following steps: weighing copper nitrate and manganese sulfate, adding a proper amount of distilled water, mixing and stirring until the copper nitrate and the manganese sulfate are completely dissolved, then adding a urea solution and a sodium chlorate solution, mixing and stirring uniformly, adding the mixed solution into a high-pressure reaction kettle, heating to 120 ℃ at the speed of 6-8 ℃/min, preserving heat for 1h, heating to 140 ℃ and preserving heat for 6h, filtering, washing, drying and grinding to obtain a CuO-MnO2 tubular composite material; mixing diatomite and attapulgite, grinding, sieving with a 200-mesh sieve, adding into an appropriate amount of acid solution, stirring at 60 deg.C for 2 hr, filtering, and washing to obtain mixed powder; adding distilled water into the mixed powder, performing ultrasonic dispersion, adding cobalt nitrate and N-methyl pyrrolidone, stirring, dissolving and dispersing uniformly, performing ultrasonic oscillation and stirring for 30min, rapidly injecting a sodium borohydride solution, dropwise adding a silver nitrate solution into the mixed solution, performing ultrasonic oscillation and stirring for 1h, adding a CuO-MnO2 tubular composite material and a proper amount of gelatin, and stirring at 60 +/-5 ℃ to completely dissolve the CuO-MnO2 tubular composite material and the gelatin to obtain a uniform colloidal mixed material; sealing and aging the colloidal mixed material for 7h, then adding excessive alcohol into the aged colloidal mixed material, filtering to obtain a gelatin-based sponge, placing the gelatin-based sponge into liquid nitrogen for quick freezing for 3min, freeze-drying, roasting at the high temperature of 500 ℃ for 6h, cooling to room temperature, grinding and crushing to obtain a mixed material; adding the mixed material into an acetone solution, uniformly dispersing, adding sorbic acid, stirring for 1h, filtering and drying to obtain the Ag-CuO-MnO2 composite bactericide, wherein in the prepared Ag-CuO-MnO2 composite bactericide, the Ag-CuO-MnO2 composite bactericide comprises Ag, CuO, MnO2, kieselguhr and attapulgite in a mass ratio of 4:2:0.8:8: 8.
The preparation method of the bactericidal coating comprises the following steps:
(1) ultrasonically stirring and uniformly mixing oxidized castor oil, graphite fluoride and 1/3 parts by weight of benzene-terminated polyisobutylene to obtain a mixed material A;
(2) putting alkyd resin, chlorinated rubber, propylene glycol and lecithin into a reaction kettle, and mechanically stirring until the alkyd resin, the chlorinated rubber, the propylene glycol and the lecithin are completely and uniformly mixed to obtain a mixed material B;
(3) heating the mixed material B in the reaction kettle to 70 ℃, adding dimethyl azodiisobutyrate and the residual 2/3 parts by weight of benzene-terminated polyisobutylene, mechanically stirring for 30min, adding the Ag-CuO-MnO2 composite bactericide and calcium carbonate powder, and mechanically stirring for 8h to obtain a mixed material C;
(4) heating the mixed material C in the reaction kettle to 120 ℃, dropwise adding the mixed material A under the condition of mechanical stirring, and after dropwise adding is finished, continuously stirring for 8 hours at 120 ℃ to obtain a mixed material D;
(5) and cooling the mixed material D to 50 ℃, adding the carboxymethyl cellulose, the dodecyl alcohol ester and the gelatin, mechanically stirring until the carboxymethyl cellulose, the dodecyl alcohol ester and the gelatin are completely dissolved and uniformly dispersed, and cooling to room temperature to obtain the bactericidal coating.
Comparative example 1
The raw materials for preparing the bactericidal coating comprise the following components in parts by mass: 32 parts of alkyd resin, 80 parts of chlorinated rubber, 5 parts of lecithin, 9 parts of carboxymethyl cellulose, 32 parts of oxidized castor oil, 11 parts of calcium carbonate powder, 4 parts of benzene-terminated polyisobutylene, 7 parts of dodecyl alcohol ester, 4 parts of dimethyl azodiisobutyrate, 14 parts of graphite fluoride, 7 parts of gelatin and 30 parts of propylene glycol.
The preparation method of the bactericidal coating comprises the following steps: ultrasonically stirring and uniformly mixing oxidized castor oil, graphite fluoride and 1/3 parts by weight of benzene-terminated polyisobutylene to obtain a mixed material A; putting alkyd resin, chlorinated rubber, propylene glycol and lecithin into a reaction kettle, and mechanically stirring until the alkyd resin, the chlorinated rubber, the propylene glycol and the lecithin are completely and uniformly mixed to obtain a mixed material B; heating the mixed material B in the reaction kettle to 70 ℃, adding dimethyl azodiisobutyrate and the residual 2/3 parts by weight of benzene-terminated polyisobutylene, mechanically stirring for 30min, adding calcium carbonate powder, mechanically stirring for 10h, heating to 120 ℃, dropwise adding the mixed material A under the condition of mechanical stirring, after dropwise adding, continuously stirring for 8h at 120 ℃, cooling to 50 ℃, adding carboxymethyl cellulose, dodecyl alcohol ester and gelatin, mechanically stirring until complete dissolution and uniform dispersion, and cooling to room temperature to obtain the mechanical coating.
Comparative example 2
The raw materials for preparing the bactericidal coating comprise the following components in parts by mass: 32 parts of alkyd resin, 80 parts of chlorinated rubber, 5 parts of lecithin, 9 parts of carboxymethyl cellulose, 32 parts of oxidized castor oil, 11 parts of calcium carbonate powder, 4 parts of benzene-terminated polyisobutylene, 7 parts of dodecyl alcohol ester, 4 parts of dimethyl azodiisobutyrate, 27 parts of Ag composite bactericide, 14 parts of graphite fluoride, 7 parts of gelatin and 30 parts of propylene glycol.
The preparation method of the Ag composite bactericide comprises the following steps: mixing diatomite and attapulgite, grinding, sieving with a 200-mesh sieve, adding into an appropriate amount of acid solution, stirring at 60 deg.C for 2 hr, filtering, and washing to obtain mixed powder; adding distilled water into the mixed powder, performing ultrasonic dispersion, adding cobalt nitrate and N-methyl pyrrolidone, stirring, dissolving and dispersing uniformly, rapidly injecting a sodium borohydride solution under ultrasonic oscillation and stirring conditions, stirring for 30min, dropwise adding a silver nitrate solution into the mixed solution, performing ultrasonic oscillation and stirring for 1h, adding a proper amount of gelatin, and stirring at 60 +/-5 ℃ to completely dissolve the gelatin to obtain a uniform colloidal mixed material; sealing and aging the colloidal mixed material for 8h, then adding excessive alcohol into the aged colloidal mixed material, filtering to obtain a gelatin-based sponge, placing the gelatin-based sponge into liquid nitrogen for quick freezing for 3min, freeze-drying, roasting at the high temperature of 500 ℃ for 6h, cooling to room temperature, grinding and crushing to obtain a mixed material; and adding the mixed material into an acetone solution, uniformly dispersing, adding sorbic acid, stirring for 1h, filtering and drying to obtain the Ag composite bactericide, wherein the mass ratio of Ag to diatomite to attapulgite in the prepared Ag composite bactericide is 5:10: 8. The preparation method of the bactericidal coating comprises the following steps: ultrasonically stirring and uniformly mixing oxidized castor oil, graphite fluoride and 1/3 parts by weight of benzene-terminated polyisobutylene to obtain a mixed material A; putting alkyd resin, chlorinated rubber, propylene glycol and lecithin into a reaction kettle, and mechanically stirring until the alkyd resin, the chlorinated rubber, the propylene glycol and the lecithin are completely and uniformly mixed to obtain a mixed material B; heating the mixed material B in the reaction kettle to 70 ℃, adding dimethyl azodiisobutyrate and the residual 2/3 parts by weight of phenyl end group polyisobutylene, mechanically stirring for 30min, adding an Ag composite bactericide and calcium carbonate powder, mechanically stirring for 10h, heating to 120 ℃, dropwise adding the mixed material A under the condition of mechanical stirring, continuously stirring for 8h after dropwise adding, cooling to 50 ℃, adding carboxymethyl cellulose, dodecyl alcohol ester and gelatin, mechanically stirring until complete dissolution and uniform dispersion, and cooling to room temperature to obtain the bactericidal coating.
Comparative example 3
The raw materials for preparing the bactericidal coating comprise the following components in parts by mass: 32 parts of alkyd resin, 80 parts of chlorinated rubber, 5 parts of lecithin, 9 parts of carboxymethyl cellulose, 32 parts of oxidized castor oil, 11 parts of calcium carbonate powder, 4 parts of benzene-terminated polyisobutylene, 7 parts of dodecyl alcohol ester, 4 parts of dimethyl azodiisobutyrate, 27 parts of CuO-MnO2 composite bactericide, 14 parts of graphite fluoride, 7 parts of gelatin and 30 parts of propylene glycol.
The preparation method of the CuO-MnO2 composite bactericide comprises the following steps: weighing copper nitrate and manganese sulfate, adding a proper amount of distilled water, mixing and stirring until the copper nitrate and the manganese sulfate are completely dissolved, then adding a urea solution and a sodium chlorate solution, mixing and stirring uniformly, adding the mixed solution into a high-pressure reaction kettle, heating to 120 ℃ at the speed of 6-8 ℃/min, preserving heat for 1h, heating to 140 ℃ and preserving heat for 6h, filtering, washing, drying and grinding to obtain a CuO-MnO2 tubular composite material; mixing diatomite and attapulgite, grinding, sieving with a 200-mesh sieve, adding into an appropriate amount of acid solution, stirring at 60 deg.C for 2 hr, filtering, and washing to obtain mixed powder; adding distilled water into the mixed powder, performing ultrasonic dispersion, adding a CuO-MnO2 tubular composite material and a proper amount of gelatin, and stirring at 60 +/-5 ℃ to completely dissolve the CuO-MnO2 tubular composite material and the gelatin to obtain a uniform colloidal mixed material; sealing and aging the colloidal mixed material for 8h, then adding excessive alcohol into the aged colloidal mixed material, filtering to obtain a gelatin-based sponge, placing the gelatin-based sponge into liquid nitrogen for quick freezing for 3min, freeze-drying, roasting at the high temperature of 500 ℃ for 6h, cooling to room temperature, grinding and crushing to obtain a mixed material; adding the mixed material into an acetone solution, uniformly dispersing, adding sorbic acid, stirring for 1h, filtering and drying to obtain the CuO-MnO2 composite bactericide, wherein in the prepared CuO-MnO2 composite bactericide, the mass ratio of CuO, MnO2, kieselguhr and attapulgite is 4:10: 8.
The preparation method of the bactericidal coating comprises the following steps: ultrasonically stirring and uniformly mixing oxidized castor oil, graphite fluoride and 1/3 parts by weight of benzene-terminated polyisobutylene to obtain a mixed material A; putting alkyd resin, chlorinated rubber, propylene glycol and lecithin into a reaction kettle, and mechanically stirring until the alkyd resin, the chlorinated rubber, the propylene glycol and the lecithin are completely and uniformly mixed to obtain a mixed material B; heating the mixed material B in a reaction kettle to 70 ℃, adding dimethyl azodiisobutyrate and the residual 2/3 parts by weight of benzene-terminated polyisobutylene, mechanically stirring for 30min, adding a CuO-MnO2 composite bactericide and calcium carbonate powder, mechanically stirring for 10h, heating to 120 ℃, dropwise adding the mixed material A under the condition of mechanical stirring, continuously stirring for 8h after dropwise adding is finished, cooling to 50 ℃, adding carboxymethyl cellulose, dodecyl alcohol ester and gelatin, mechanically stirring until the materials are completely dissolved and uniformly dispersed, and cooling to room temperature to obtain the bactericidal coating.
Comparative example 4
The raw materials for preparing the bactericidal coating comprise the following components in parts by mass: 32 parts of alkyd resin, 80 parts of chlorinated rubber, 5 parts of lecithin, 9 parts of carboxymethyl cellulose, 32 parts of oxidized castor oil, 11 parts of calcium carbonate powder, 4 parts of benzene-terminated polyisobutylene, 7 parts of dodecyl alcohol ester, 4 parts of dimethyl azodiisobutyrate, 27 parts of Ag-CuO-MnO2 composite bactericide, 14 parts of graphite fluoride, 7 parts of gelatin and 30 parts of propylene glycol.
The preparation method of the Ag-CuO-MnO2 composite bactericide is the same as that of example 2.
The preparation method of the bactericidal coating comprises the following steps: putting alkyd resin, chlorinated rubber, propylene glycol, lecithin, oxidized castor oil, graphite fluoride and 1/3 parts by weight of benzene-terminated polyisobutylene into a reaction kettle, mechanically stirring until the mixture is completely and uniformly mixed, heating to 70 ℃, adding dimethyl azodiisobutyrate and the rest 2/3 parts by weight of benzene-terminated polyisobutylene, mechanically stirring for 30min, adding Ag-CuO-MnO2 composite bactericide and calcium carbonate powder, mechanically stirring for 10h, heating to 120 ℃, continuously stirring for 8h, cooling to 50 ℃, adding carboxymethyl cellulose, dodecyl alcohol ester and gelatin, mechanically stirring until the mixture is completely and uniformly dissolved and dispersed, and cooling to room temperature to obtain the bactericidal coating.
Comparative example 5
The raw materials for preparing the bactericidal coating comprise the following components in parts by mass: 32 parts of alkyd resin, 80 parts of chlorinated rubber, 5 parts of lecithin, 9 parts of carboxymethyl cellulose, 11 parts of calcium carbonate powder, 4 parts of benzene-terminated polyisobutylene, 7 parts of dodecyl alcohol ester, 4 parts of dimethyl azodiisobutyrate, 27 parts of Ag-CuO-MnO2 composite bactericide, 7 parts of gelatin and 30 parts of propylene glycol.
The preparation method of the Ag-CuO-MnO2 composite bactericide is the same as that of example 2.
The preparation method of the bactericidal coating comprises the following steps:
(1) putting alkyd resin, chlorinated rubber, benzene-terminated polyisobutylene, propylene glycol and lecithin into a reaction kettle, mechanically stirring until the alkyd resin, the chlorinated rubber, the benzene-terminated polyisobutylene, the propylene glycol and the lecithin are completely and uniformly mixed, heating to 70 ℃, adding dimethyl azodiisobutyrate, mechanically stirring for 30min, adding an Ag-CuO-MnO2 composite bactericide and calcium carbonate powder, mechanically stirring for 10h, cooling to 50 ℃, adding carboxymethyl cellulose, dodecyl alcohol ester and gelatin, mechanically stirring until the carboxymethyl cellulose, the dodecyl alcohol ester and the gelatin are completely dissolved and uniformly dispersed, and cooling to room temperature to obtain the bactericidal coating.
The bactericidal coatings prepared in examples 1 to 3 of the present invention and the coatings prepared in comparative examples 4 and 5 were respectively subjected to performance tests, and the test results are shown in table 1:
TABLE 1
Figure BDA0001697483900000201
As can be seen from the data in Table 1, the bactericidal coating provided by the invention has good properties of hardness, adhesion, salt spray resistance, impact resistance and the like.
The bactericidal coatings prepared in examples 1-3 of the invention and the coatings prepared in comparative examples 1-3 are respectively subjected to bacteriostatic performance detection, the bactericidal performance of the coatings is detected by a bacteriostatic circle method, and the bactericidal performance of the coatings is reflected by a bactericidal test of staphylococcus aureus, wherein the detection method comprises the following steps:
1. experimental strains: staphylococcus aureus ATCC 6538.
2. And (3) strain culture medium: nutrient agar medium, nutrient broth medium.
3. The specific experimental steps are as follows:
(1) preparing the drug sensitive tablet: qualitative filter paper is made into round paper sheet with diameter of 6mm by puncher, and is autoclaved at 121 deg.C for 30min, and then cooled. Then respectively spraying the coatings of examples 1-3 and comparative examples 1-3 on one surface of a filter paper sheet by a spray gun under the aseptic condition for 0.5mm, drying to prepare a drug sensitive sheet, preparing 5 drug sensitive sheets for each coating, preparing 5 blank sterilized paper sheets as a control group, and sterilizing a culture dish, a measuring cylinder, a syringe, a puncher, distilled water, a culture medium and the like at 121 ℃ for 30 min;
(2) preparing a bacterial liquid: placing staphylococcus aureus strains in 10ml of nutrient broth culture medium, culturing at 37 ℃ for 18h, respectively taking 1ml of culture solution, adding 9ml of 0.9% sterile sodium chloride solution, and diluting the strain solution to 1.05 x 106cfu/ml by adopting a 10-time incremental dilution method for later use;
(3) putting a nutrient agar culture medium into a culture dish to prepare a planar nutrient agar culture medium, uniformly inoculating the bacterial liquid on the plane of the nutrient agar culture medium, paving the drug sensitive tablets on the surface of the culture medium, putting the culture dish into a biochemical incubator, culturing for 24 hours at constant temperature of 37 ℃, measuring the diameter of a bacteriostatic circle of each drug sensitive tablet, and calculating the average value of the diameters of the bacteriostatic circles of each group.
The results of the experiment are shown in table 2:
TABLE 2
Figure BDA0001697483900000211
The experimental results show that the bactericidal coatings of the embodiments 1 to 3 have good bacteriostatic effect, and the bacteriostatic performance of the paint can be obviously improved by compounding the materials.
As shown in fig. 2, the power unit 17 in this embodiment is a micro hydraulic cylinder, a hydraulic chamber 24 is disposed in the housing 1, a micro hydraulic pump 25 is mounted on the hydraulic chamber 24, and the micro hydraulic pump 25 is communicated with the micro hydraulic cylinder and the hydraulic chamber 24 through a pipeline 26. In addition, the power part 17 may be an electric telescopic rod.
As shown in fig. 2, the upper bite plate 2 and the lower bite plate 3 of the present embodiment are both arc-shaped plates, and the upper slide bar 14 and the lower slide bar 16 connected to the upper bite plate 2 and the lower bite plate 3, respectively, are provided with bent portions 27 protruding outward. Is convenient to match with the shape of the teethridge or teethridge.
The invention also provides a use method of the rehabilitation training system after the radiation therapy of the oral tumor, which comprises the rehabilitation training system and the use method thereof as follows:
(1) in the initial state, the transverse power mechanism drives the raised head 19 to retract, the upper bite plate 2 and the lower bite plate 3 are in a closed state, and the upper bite plate 2 and the lower bite plate 3 are placed in the oral cavity of a patient and are respectively contacted with the upper and lower gums of the patient;
(2) then, manually operating to open the upper bite plate 2 and the lower bite plate 3, detecting the change of the position of the magnetic induction sheet 22 by the magnetic sensing chip 23 to obtain the motion data of the upper and lower teethridge of the patient, and storing the motion data into the controller 4 by the magnetic sensing chip 23 to form a motion curve;
(3) the working mode of the motor 7 is set through the controller 4, and the power component 17 works according to the acquired motion curve, so that the upper biting plate 2 and the lower biting plate 3 can move transversely while opening and closing the oral cavity of the patient, and the oral rehabilitation training is started;
(4) when the oral rehabilitation training is finished, the upper bite plate 2 and the lower bite plate 3 are taken out of the oral cavity of the patient in a closed state.
The working mode of the motor 7 in the step (3) comprises the times and the groups of rehabilitation training formed by the opening and closing of the upper biting plate 2 and the lower biting plate 3 driven by the motor 7.
Furthermore, in the using method of the embodiment, the number of times of rehabilitation training is 2-6 times per minute, the number of groups of rehabilitation training is 5-10, and the interval time of each group is 2-5 minutes, so that medical staff or patients can conveniently control the rehabilitation time and frequency by setting.
According to the invention, the motor 7, the transverse power mechanism and the controller 4 are arranged, so that the upper biting plate 2 and the lower biting plate 3 can automatically work, the use and the management are convenient, the rehabilitation effect of the oral cavity of a patient can be effectively improved, the rehabilitation time is shortened, and the labor intensity of medical staff and the like is reduced.
The technical contents not described in detail in the present invention are all known techniques.

Claims (7)

1. A rehabilitation training system after oral tumor radiotherapy comprises a shell, an upper bite plate, a lower bite plate and a controller, and is characterized in that a first vertical supporting plate and a second vertical supporting plate are arranged in the shell, and the first supporting plate and the second supporting plate are arranged in parallel and fixed with the inner wall of the shell respectively; first supportA bite plate control mechanism is arranged between the plate and the inner wall of the shell, the bite plate control mechanism comprises a motor, a gear, a first rack and a second rack, a motor shaft is arranged on the motor, the gear is mounted on the motor shaft, the end part of the motor shaft penetrating through the gear is connected with the shell through a bearing, the first rack and the second rack are meshed with the gear, the first rack and the second rack are respectively matched with clamping rails fixedly mounted on opposite surfaces of the shell and the first supporting plate, the first rack and the second rack slide along the clamping rails under the driving of the gear, the side surface of the upper end of the first rack is fixedly connected with one end of a transverse upper connecting rod, the other end of the upper connecting rod penetrates through the second supporting plate and then is connected with an upper sliding rod, one end of the upper sliding rod extends into the upper connecting rod, and; the side face of the lower end of the second rack is fixedly connected with one end of a transverse lower connecting rod, the other end of the lower connecting rod penetrates through the second supporting plate and then is connected with a lower sliding rod, one end of the lower sliding rod extends into the lower connecting rod, and the other end of the lower sliding rod penetrates through the shell and then is fixedly connected with a lower biting plate; the upper connecting rod and the lower connecting rod are of sleeve structures, a transverse power mechanism is installed in each sleeve structure and comprises a power part, a straight rod and a raised head, the front end of each raised head is provided with a groove, the end parts of the upper sliding rod and the lower sliding rod are respectively provided with a clamping groove matched with the raised head, a magnetic induction sheet is installed in each clamping groove, a magnetic sensing chip is installed in each groove, the magnetic sensing chip and the magnetic induction sheet are used for acquiring moving data of the upper sliding rod relative to the upper connecting rod and the lower sliding rod relative to the lower connecting rod, a limit baffle is arranged between the power part and the clamping grooves, a raised head through hole is formed in the middle of the limit baffle, and the magnetic; the outer wall of the shell, the first supporting plate and the second supporting plate are respectively provided with a sterilization coating, and the raw materials for preparing the sterilization coating comprise the following components in parts by mass: 28-36 parts of alkyd resin, 70-90 parts of chlorinated rubber, 3-6 parts of lecithin, 8-10 parts of carboxymethyl cellulose, 30-35 parts of oxidized castor oil, 9-13 parts of calcium carbonate powder, 3-5 parts of benzene-terminated polyisobutylene, 6-8 parts of dodecyl alcohol ester, 2-5 parts of dimethyl azodiisobutyrate, Ag-CuO-MnO224-30 parts of composite bactericide, 12-16 parts of graphite fluoride, 5-9 parts of gelatin and 20-40 parts of propylene glycol.
2. According to the claimsThe rehabilitation training system after the oral tumor radiotherapy is characterized in that the sterilization coating is prepared from the following raw materials in parts by mass: 28 parts of alkyd resin, 70 parts of chlorinated rubber, 3 parts of lecithin, 8 parts of carboxymethyl cellulose, 30 parts of oxidized castor oil, 9 parts of calcium carbonate powder, 3 parts of benzene-terminated polyisobutylene, 6 parts of dodecyl alcohol ester, 2 parts of dimethyl azodiisobutyrate, and Ag-CuO-MnO224 parts of composite bactericide, 12 parts of graphite fluoride, 5 parts of gelatin and 20 parts of propylene glycol.
3. The rehabilitation training system after oral tumor radiotherapy according to claim 1, wherein the bactericidal coating is prepared from the following raw materials in parts by mass: 32 parts of alkyd resin, 80 parts of chlorinated rubber, 5 parts of lecithin, 9 parts of carboxymethyl cellulose, 32 parts of oxidized castor oil, 11 parts of calcium carbonate powder, 4 parts of benzene-terminated polyisobutylene, 7 parts of dodecyl alcohol ester, 4 parts of dimethyl azodiisobutyrate, and Ag-CuO-MnO227 parts of composite bactericide, 14 parts of graphite fluoride, 7 parts of gelatin and 30 parts of propylene glycol.
4. The post-radiotherapy rehabilitation training system for oral tumors of any one of claims 1-3, wherein the Ag-CuO-MnO is2The preparation method of the composite bactericide comprises the following steps:
(1) weighing copper nitrate and manganese sulfate, adding a proper amount of distilled water, mixing and stirring until the copper nitrate and the manganese sulfate are completely dissolved, then adding a urea solution and a sodium chlorate solution, mixing and stirring uniformly, adding the mixed solution into a high-pressure reaction kettle, heating to 120 ℃, keeping the temperature for 1h, heating to 140 ℃, keeping the temperature for 6h, filtering, washing, drying and grinding to obtain CuO-MnO2A tubular composite material;
(2) mixing diatomite and attapulgite, grinding, sieving with a 200-mesh sieve, adding into an appropriate amount of acid solution, stirring at 60 deg.C for 2 hr, filtering, and washing to obtain mixed powder;
(3) adding distilled water into the mixed powder prepared in the step (2), adding cobalt nitrate and N-methyl pyrrolidone after ultrasonic dispersion, stirring, dissolving and dispersing uniformly, and performing ultrasonic oscillationRapidly injecting sodium borohydride solution under the stirring condition, stirring for 30min, then dropwise adding silver nitrate solution into the mixed solution, ultrasonically oscillating and stirring for 1h, and then adding the CuO-MnO prepared in the step (1)2Stirring the tubular composite material and a proper amount of gelatin at 60 +/-5 ℃ to completely dissolve the tubular composite material and the gelatin to obtain a uniform colloidal mixed material;
(4) sealing and aging the colloidal mixed material prepared in the step (3), adding excessive alcohol into the aged colloidal mixed material, filtering to obtain a gelatin-based sponge, placing the gelatin-based sponge into liquid nitrogen for quick freezing for 3min, roasting at the high temperature of 650 ℃ for 4-6h after freeze drying, cooling to room temperature, and grinding and crushing to obtain a mixed material;
(5) adding the mixed material obtained in the step (4) into an acetone solution, uniformly dispersing, adding sorbic acid, stirring for 1h, filtering and drying to obtain the Ag-CuO-MnO2A composite bactericide.
5. The system of claim 1, wherein the power unit is an electric telescopic rod.
6. The rehabilitation training system after oral tumor radiotherapy according to claim 1, wherein the power component is a micro hydraulic cylinder, a hydraulic chamber is arranged in the housing, a micro hydraulic pump is mounted on the hydraulic chamber, and the micro hydraulic pump is communicated with the micro hydraulic cylinder and the hydraulic chamber through a pipeline.
7. The system of claim 1, wherein the upper bite plate and the lower bite plate are both arc-shaped plates, and the upper slide bar and the lower slide bar respectively connected to the upper bite plate and the lower bite plate are both provided with a bending portion protruding outward.
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