CN109011202B

CN109011202B - Human body auxiliary positioning device for radiotherapy and use method thereof

Info

Publication number: CN109011202B
Application number: CN201810619334.5A
Authority: CN
Inventors: 佟奎
Original assignee: Qingdao Nuode Intellectual Property Co ltd
Current assignee: Qingdao Pansi Technology Co ltd
Priority date: 2018-06-15
Filing date: 2018-06-15
Publication date: 2021-01-01
Anticipated expiration: 2038-06-15
Also published as: CN109011202A

Abstract

A human body auxiliary positioning device for radiotherapy and a using method thereof are provided, the human body auxiliary positioning device comprises a treatment bed, two sides of the treatment bed are provided with constraint molds, each constraint mold comprises a left side positioning mechanism and a right side positioning mechanism which are oppositely arranged, each of the left side positioning mechanism and the right side positioning mechanism is provided with a vertical plate, a movable plate, an arc-shaped positioning plate and an adjusting shaft, and the lower part of each vertical plate is provided with an elastic clamping mechanism connected with the edge of the treatment bed; the front of riser upper portion is opened there is the bar mouth, installs the fly leaf in the bar mouth, and the fly leaf shape all opens the strip with the cooperation of bar mouth, riser upper portion, fly leaf side and passes through the groove, and the adjusting shaft passes the strip of riser, fly leaf in proper order and passes through installation positioning nut behind the groove, can adjust the relative height of fly leaf on the riser and the length that the fly leaf stretched into to the inboard through the adjusting shaft. The invention can provide external force restraint for the thoracic cavity part of a patient, can effectively inhibit the influence of respiratory motion on the change of the tumor position, improves the accuracy of radiotherapy and improves the effect of tumor radiotherapy.

Description

Human body auxiliary positioning device for radiotherapy and use method thereof

Technical Field

The invention relates to the field of medical instruments, in particular to a human body auxiliary positioning device for radiotherapy and a using method thereof.

Background

Radiotherapy, or radiotherapy, is a therapy for killing malignant tumor by inhibiting its growth by irradiating it with radiation, and its basic principle is to destroy malignant tumor and preserve normal tissue.

With the development of radiation physics, radiobiology, clinical oncology and various radiotherapy devices, radiotherapy has become three main means for treating tumors together with surgical treatment and chemotherapy, and about 70% of patients with malignant tumors need radiotherapy. In external irradiation treatment machines, a medical electron linear accelerator is commonly used, followed by a cobalt 60 teletherapy machine. In the internal irradiation therapeutic machine, an isotope after-loading machine is mainly used.

At present, when radiotherapy is clinically carried out on a patient, each part of the body of the patient needs to be fixed by adopting a body position fixing device, and the irradiated part is prevented from moving when irradiation is carried out, so that the irradiated dose of normal tissues is reduced, and the target area is ensured to be sufficiently irradiated. For example, the conventional medical electron linear accelerator adopts a motion system of an isocenter principle, i.e., the rotation axes of the gantry, the radiation head and the treatment couch intersect at a point called an isocenter, and the center error is required to be within ± 2 mm.

The selection of the radiotherapy body position not only ensures that the patient obtains the correct treatment body position, but also ensures that the body position keeps stable in the irradiation process, and meanwhile, the repeatability of each positioning is also considered. For the tumor in the chest, the respiratory motion can cause the position of the tumor to change greatly, although the four-dimensional treatment system can realize more accurate following positioning, the relative investment is larger, and the existing treatment equipment still has more three-dimensional treatment modes, so that the more accurate tumor positioning is very necessary by combining the three-dimensional tumor radiotherapy mode.

For example, the Chinese patent (publication No. CN 105079973B) discloses a fixing device for prone position of radiotherapy, which comprises a base and a slide block, wherein the slide block is arranged on the base and moves along the base, and the slide block is provided with a concave groove matched with part of the body of a patient. When the prone posture fixing device is used, a patient can lie on the prone posture fixing device for radiotherapy (face down), at the moment, some body parts of the patient are placed in the concave grooves, and the patient is fixed on the sliding block (by using an external device or a buckling part), so that subsequent disease treatment (such as radiotherapy) is facilitated.

Further, as disclosed in chinese patent (publication No. CN 104689479B), "an air bag bionic cradle bed for radiotherapy apparatus", the air bag bionic cradle bed is provided with one or more air bags in the bottom bed surface direction of the bed plate, and a control switch and a bidirectional air pump corresponding to the air bags, wherein the air pump inflates or deflates the air bags according to the breathing frequency and time phase to make the air bag bionic cradle bed move up and down. The cradle bed can be additionally provided with a synchronous multi-axis controller, and the synchronous multi-axis controller controls the combined motor and the motion of the air bag according to the respiration gating signals to guide the air bag bionic cradle bed to synchronously do cradle-like motion in the direction opposite to the target region motion direction caused by respiration.

The existing dynamic tumor radiotherapy can not realize the relatively accurate positioning requirement on the tumor; in addition, the immunity of the patient after radiotherapy can be reduced, and the existing radiotherapy equipment and auxiliary devices need continuous maintenance, cleaning and sterilization, so that the effective self-sterilization effect cannot be realized.

Disclosure of Invention

The invention provides a human body auxiliary positioning device for radiotherapy and a using method thereof, which are used for solving the problems in the prior art.

In order to realize the purpose of the invention, the following technical scheme is adopted:

a human body auxiliary positioning device for radiotherapy comprises a treatment bed, wherein constraint molds are arranged on two sides of the treatment bed and comprise a left side positioning mechanism and a right side positioning mechanism which are arranged oppositely, the left side positioning mechanism and the right side positioning mechanism are respectively provided with a vertical plate, a movable plate, an arc-shaped positioning plate and an adjusting shaft, and the lower part of the vertical plate is provided with an elastic clamping mechanism connected with the edge of the treatment bed; the front surface of the upper part of the vertical plate is provided with a strip-shaped opening, a movable plate is arranged in the strip-shaped opening, the shape of the movable plate is matched with the strip-shaped opening, strip-shaped through grooves are formed in the side surface of the upper part of the vertical plate and the side surface of the movable plate, a positioning nut is arranged after an adjusting shaft sequentially penetrates through the strip-shaped through grooves of the vertical plate and the movable plate, and the relative height of the movable plate on the vertical plate and the length of the movable; the arc-shaped positioning plate is arranged on the front side of the inner end of the movable plate, the arc-shaped positioning plate and the movable plate are movably mounted through a connecting rod, a clamping block is mounted at the upper end of the arc-shaped positioning plate of the left positioning mechanism, a clamping groove is formed in the clamping block, a reel box is mounted at the upper end of the arc-shaped positioning plate of the right positioning mechanism, a reel is mounted in the reel box, an elastic pressing belt is wound on the reel, a clamping head is arranged at the end part of the elastic pressing belt extending out of the reel box; the adjusting shaft comprises an outer cylinder and an inner cylinder, the inner cylinder is sleeved in the outer cylinder, a first spring is arranged between the bottom surface of the outer cylinder and the inner end of the inner cylinder, and the outer end of the inner cylinder extends out of the outer cylinder; the side wall of the outer cylinder is positioned on the movable plate partThe movable plate is provided with a rectangular opening, an elastic clamping piece protruding towards the movable plate is installed in the rectangular opening, one end of the elastic clamping piece is hinged with the side wall of the outer barrel, the other end of the elastic clamping piece can be retracted into the outer barrel and provided with a fixed block, a sliding groove is formed in the inner side of the fixed block, a supporting vertical rod is arranged in the sliding groove, one end of the supporting vertical rod is movably contacted with the sliding groove, the other end of the supporting vertical rod is fixed with the inner barrel wall, and the movable plate can be; the elastic clamping mechanism comprises an upper transverse plate, a lower transverse plate, a clamping plate and an elastic bolt, the clamping plate is arranged between the upper transverse plate and the lower transverse plate, the side edges of the same sides of the upper transverse plate and the lower transverse plate are fixed with a vertical plate, an inner threaded hole is formed in the lower transverse plate, the elastic bolt is installed on the inner threaded hole, the clamping plate is fixedly installed on the elastic bolt, the upper end of the elastic bolt is flush with the upper edge of the clamping plate, a downward deep hole is formed in the upper end of the elastic bolt, a pressing block, a first sliding rod, a third spring, a limiting block and a limiting ring are installed in the deep hole, the pressing block and the limiting block are respectively installed at the upper end and the lower end of the first sliding rod, the third spring is sleeved on the first; the vertical plate, the movable plate and the arc-shaped positioning plate are all provided with a sterilization coating, and the raw materials for preparing the sterilization coating comprise the following components in parts by mass: 28-36 parts of alkyd resin, 70-90 parts of chlorinated rubber, 3-6 parts of lecithin, 8-10 parts of carboxymethyl cellulose, 30-35 parts of oxidized castor oil, 9-13 parts of calcium carbonate powder, 3-5 parts of benzene-terminated polyisobutylene, 6-8 parts of dodecyl alcohol ester, 2-5 parts of dimethyl azodiisobutyrate, Ag-CuO-MnO₂24-30 parts of composite bactericide, 12-16 parts of graphite fluoride, 5-9 parts of gelatin and 20-40 parts of propylene glycol.

In order to further realize the purpose of the invention, the following technical scheme can be adopted:

the auxiliary positioning device for the radiotherapy comprises the following raw materials in parts by mass: 28 parts of alkyd resin, 70 parts of chlorinated rubber, 3 parts of lecithin, 8 parts of carboxymethyl cellulose, 30 parts of oxidized castor oil, 9 parts of calcium carbonate powder, 3 parts of benzene-terminated polyisobutylene, 6 parts of dodecyl alcohol ester, 2 parts of dimethyl azodiisobutyrate, and Ag-CuO-MnO ₂24 parts of composite bactericide and fluorite12 parts of ink, 5 parts of gelatin and 20 parts of propylene glycol.

The auxiliary positioning device for the radiotherapy comprises the following raw materials in parts by mass: 32 parts of alkyd resin, 80 parts of chlorinated rubber, 5 parts of lecithin, 9 parts of carboxymethyl cellulose, 32 parts of oxidized castor oil, 11 parts of calcium carbonate powder, 4 parts of benzene-terminated polyisobutylene, 7 parts of dodecyl alcohol ester, 4 parts of dimethyl azodiisobutyrate, and Ag-CuO-MnO₂27 parts of composite bactericide, 14 parts of graphite fluoride, 7 parts of gelatin and 30 parts of propylene glycol.

The Ag-CuO-MnO-body auxiliary positioning device for radiotherapy₂The preparation method of the composite bactericide comprises the following steps:

(1) weighing copper nitrate and manganese sulfate, adding a proper amount of distilled water, mixing and stirring until the copper nitrate and the manganese sulfate are completely dissolved, then adding a urea solution and a sodium chlorate solution, mixing and stirring uniformly, adding the mixed solution into a high-pressure reaction kettle, heating to 120 ℃, keeping the temperature for 1h, heating to 140 ℃, keeping the temperature for 6h, filtering, washing, drying and grinding to obtain CuO-MnO₂A tubular composite material;

(2) mixing diatomite and attapulgite, grinding, sieving with a 200-mesh sieve, adding into an appropriate amount of acid solution, stirring at 60 deg.C for 2 hr, filtering, and washing to obtain mixed powder;

(3) adding distilled water into the mixed powder prepared in the step (2), performing ultrasonic dispersion, adding cobalt nitrate and N-methylpyrrolidone, stirring, dissolving and dispersing uniformly, performing ultrasonic oscillation and stirring for 30min, rapidly injecting a sodium borohydride solution, stirring, dropwise adding a silver nitrate solution into the mixed solution, performing ultrasonic oscillation and stirring for 1h, and adding the CuO-MnO prepared in the step (1)₂Stirring the tubular composite material and a proper amount of gelatin at 60 +/-5 ℃ to completely dissolve the tubular composite material and the gelatin to obtain a uniform colloidal mixed material;

(4) sealing and aging the colloidal mixed material prepared in the step (3), adding excessive alcohol into the aged colloidal mixed material, filtering to obtain a gelatin-based sponge, placing the gelatin-based sponge into liquid nitrogen for quick freezing for 3min, roasting at the high temperature of 650 ℃ for 4-6h after freeze drying, cooling to room temperature, and grinding and crushing to obtain a mixed material;

(5) adding the mixed material obtained in the step (4) into an acetone solution, uniformly dispersing, adding sorbic acid, stirring for 1h, filtering and drying to obtain the Ag-CuO-MnO₂A composite bactericide.

According to the auxiliary positioning device for the radiotherapy, the center of the elastic clamping piece is provided with the through hole, the through hole is internally provided with the movable column, the end part of the movable column, which is positioned at the inner side of the elastic clamping piece, is provided with the horizontal second spring, and the inner end of the second spring is fixed with the side wall of the outer cylinder; the connecting end of the movable column and the second spring is fixedly connected with a metal pull rope, the other end of the metal pull rope penetrates through the side wall of the outer barrel and then is fixed with the lower portion of the inner barrel, and the pull rope is located below the supporting cross rod.

According to the human body auxiliary positioning device for radiotherapy, the inner wall of the strip-shaped through groove of the movable plate is provided with a plurality of positioning holes at intervals, and the outer end of the movable column can extend into the positioning holes; the through hole and the movable column are both conical, and the diameter of the outer end of the movable column is larger than that of the inner side of the through hole.

The auxiliary positioning device for the radiotherapy comprises 2 sets of elastic clamping pieces, wherein the elastic clamping pieces are symmetrically arranged on the side wall of the outer cylinder; the first spring sleeve is arranged on the vertical guide rod in a sleeved mode, the lower end of the guide rod is fixed to the inner bottom of the outer cylinder, and the upper end of the guide rod extends into the inner cylinder.

According to the human body auxiliary positioning device for radiotherapy, the second slide bar is installed on the lower side of the limiting block, the fourth spring is sleeved on the second slide bar, the upper end of the fourth spring is fixed with the second slide bar, the bottom of the deep hole is provided with the boss, and the width of the boss is located between the second slide bar and the fourth spring.

The invention also provides a use method of the human body auxiliary positioning device for radiotherapy, which comprises the human body auxiliary positioning device and comprises the following steps:

firstly, a patient lies on a treatment bed in a lying way and the body position of the patient is preliminarily adjusted;

secondly, the left positioning mechanism and the right positioning mechanism are respectively and symmetrically arranged on two sides of the thoracic cavity part of the patient through an elastic clamping mechanism;

operating the adjusting shaft to separate the movable plate from the strip-shaped opening of the vertical plate, adjusting the height of the movable plate on the vertical plate and the inward extending length of the movable plate, attaching the arc-shaped positioning plate to the body contact part of the patient, and accurately positioning the body position of the patient;

and fourthly, pulling out the elastic compression belt to enable the chuck to be matched with the clamping groove, and enabling the elastic compression belt to restrain the chest part of the patient so as to control the displacement of the dynamic tumor along with the respiration and improve the accuracy of radiotherapy.

The invention has the beneficial effects that:

1. the human body auxiliary positioning device is provided with the restraint die, and can provide external force restraint for the thoracic cavity part of a patient, so that the influence of respiratory motion on the change of the tumor position can be effectively inhibited, the accuracy of radiotherapy is improved, the restraint die comprises the left side positioning mechanism, the right side positioning mechanism and the elastic compression belt which are oppositely arranged, the installation and the use are convenient, the body position of the patient during radiotherapy can be accurately positioned through the left side positioning mechanism and the right side positioning mechanism, and better and more accurate tumor radiotherapy is realized.

2. Left side positioning mechanism, right side positioning mechanism all are equipped with riser, fly leaf, arc locating plate and regulating spindle, and the riser lower part is fixed through coupling mechanism with the treatment bed side, and openly open on riser upper portion has the bar mouth, installs the fly leaf in the bar mouth, and the fly leaf shape cooperates with the bar mouth, and the groove is passed through to the bar has all been opened to riser upper portion side, fly leaf side, can adjust the relative height of fly leaf on the riser and the length that the fly leaf stretched into to the inboard through the regulating spindle. 2 arc locating plate sets up patient health both sides relatively, then can provide external force through elasticity compressing band to patient's health and fix to can avoid rocking of patient at the radiotherapy in-process, influence treatment. Because arc locating plate, elasticity compressing band are all can dismantle, make things convenient for patient's position adjustment and have better assistance-localization real-time effect, can not produce great extrusion to patient's health, improve the comfort level of using.

3. By using the strip-shaped openings formed in the vertical plates, the movable plate can be folded to the middle of the vertical plates after the arc-shaped positioning plates are removed, so that the movable plate is convenient for restraining the die to be accommodated; when the elastic clamping mechanism is arranged on the treatment bed, the connection stability of the elastic clamping mechanism and the treatment bed can be improved by utilizing the elastic structure in the elastic bolt.

4. The invention is characterized in that the vertical plate, the movable plate and the arc positioning plate are all provided with a sterilization coating, alkyd resin and chlorinated rubber are used as main materials, the sterilization coating is matched with graphite fluoride, oxidized castor oil, Ag-CuO-MnO2 composite bactericide and other additives to obtain the formula proportion of the sterilization coating, the graphite fluoride and the oxidized castor oil are matched with the alkyd resin and the chlorinated rubber to improve the wear resistance, the corrosion resistance and the hardness of the sterilization coating, the structure of the oxidized castor oil and the structures of the alkyd resin and the chlorinated rubber are mutually penetrated and penetrated to form an interpenetrating network structure, the Ag-CuO-MnO2 composite bactericide and calcium carbonate powder are penetrated in the sterilization coating, the paint has the advantages of uniform dispersion, difficult precipitation, fast drying of a coating film, uniform film formation, compact structure of the coating film, strong adhesive force and good water-proof permeability, and can be firmly attached to the surface of an object to be coated.

5. The Ag-CuO-MnO2 composite bactericide in the bactericidal coating has a continuous carbon layer with a porous structure, can be better crosslinked with other materials in the coating after modification, is uniformly distributed in an interpenetrating network structure of the coating and is not easy to separate out, the bactericidal effect is also completed under the mutual synergistic effect of four materials, namely a nano silver hollow sphere, a CuO-MnO2 tubular composite material, diatomite and attapulgite, the composite bactericide has a plurality of porous structures with different sizes and is easier to adsorb bacteria, moreover, the silver in the Ag-CuO-MnO2 composite bactericide is of a hollow sphere structure, the generated nano silver hollow sphere is coated on the diatomite and the attapulgite, the CuO is coated on the tubular MnO2, and the nano silver hollow sphere and the CuO are communicated with each other, so that the bactericidal and antibacterial effects can be better promoted; firstly, the composite bactericide has a plurality of porous structures with different sizes, which can efficiently and quickly adsorb bacteria, the nano-silver hollow spheres are distributed on the surfaces of diatomite, attapulgite and CuO-MnO2 tubular composite materials, the nano-silver hollow spheres and the nano-CuO are communicated with each other, the particle diameters of the nano-silver hollow spheres and the nano-CuO are small and uniformly distributed, the nano-silver hollow spheres can be quickly adsorbed on the surface of a bacterial cell membrane to block the normal substance transmission of the bacteria and destroy the physiological function of the bacteria, the nano-CuO penetrates through the bacterial cell membrane to enter the inside of the bacteria to inhibit the growth of the bacteria, and the nano-silver hollow spheres, the CuO-2 tubular composite materials, the diatomite and the attapulgite are mutually matched to act, so that the.

6. The bactericidal coating disclosed by the invention is compact in film structure, can be firmly attached to the surface of an object to be coated, is strong in adhesive force, has better wear resistance and corrosion resistance, also has good pollution resistance and bactericidal and bacteriostatic properties, breaks through the defects of the traditional mechanical coating, can kill bacteria, inhibit the growth of bacteria, is safe and environment-friendly, provides a safer, healthier and cleaner environment for equipment users, and can be widely applied to the fields of medical equipment, toys for children, electrical appliances, health-care and fitness equipment, other common equipment and the like.

Drawings

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is an enlarged view of section I of FIG. 1;

FIG. 3 is an enlarged view taken from the direction A of FIG. 1;

FIG. 4 is a schematic view of the left positioning mechanism of FIG. 3;

FIG. 5 is a schematic view of the right positioning mechanism of FIG. 3;

FIG. 6 is a schematic structural view of the elastic clamping mechanism of FIG. 3;

FIG. 7 is a schematic structural view of the adjustment shaft of FIG. 3;

FIG. 8 is another state reference diagram of FIG. 7;

FIG. 9 is a sectional view taken along line B-B of FIG. 7;

fig. 10 is a partially enlarged view of ii in fig. 8.

Reference numerals: 1-base, 2-treatment bed, 3-left side positioning mechanism, 4-right side positioning mechanism, 5-vertical plate, 6-movable plate, 7-arc positioning plate, 8-connecting rod, 9-adjusting shaft, 10-rotating handle, 11-strip-shaped opening, 12-strip-shaped through groove, 13-clamping block, 14-reel box, 15-elastic pressing belt, 16-outer barrel, 17-inner barrel, 18-first spring, 19-rectangular opening, 20-elastic clamping piece, 21-supporting vertical rod, 22-movable column, 23-second spring, 24-metal pull rope, 25-guide rod, 26-upper transverse plate, 27-lower transverse plate, 28-clamping plate, 29-elastic bolt, 30-deep hole, 31-pressing block, 32-a first slide bar, 33-a third spring, 34-a limiting block, 35-a limiting ring, 36-a second slide bar, 37-a fourth spring, 38-a boss and 39-a tightening handle.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

As shown in fig. 1-10, the present embodiment discloses a human body auxiliary positioning device for radiotherapy, which comprises a treatment couch, and the constraining molds disposed on two sides of the treatment couch comprise a left positioning mechanism 3 and a right positioning mechanism 4 disposed oppositely.

The left positioning mechanism 3 and the right positioning mechanism 4 are respectively provided with a vertical plate 5, a movable plate 6, an arc positioning plate 7 and an adjusting shaft 9, and the lower part of the vertical plate 5 is provided with an elastic clamping mechanism connected with the edge of the treatment bed; the front of the upper portion of the vertical plate 5 is provided with a strip-shaped opening 11, the movable plate 6 is installed in the strip-shaped opening 11, the shape of the movable plate 6 is matched with the strip-shaped opening 11, the side surface of the upper portion of the vertical plate 5 and the side surface of the movable plate 6 are provided with strip-shaped through grooves 12, the adjusting shaft 9 sequentially penetrates through the strip-shaped through grooves 12 of the vertical plate 5 and the movable plate 6 and then is provided with a positioning nut, and the relative height of the movable plate 6 on the vertical plate 5 and the length of the movable plate.

Arc locating plate 7 sets up in fly leaf 6 inner front side, through connecting rod 8 movable mounting between arc locating plate 7 and the fly leaf 6, left side positioning mechanism 3's arc locating plate upper end installation fixture block 13 is provided with the draw-in groove on the fixture block 13, right side positioning mechanism 4's arc locating plate upper end installation reel box 14, installation spool in the reel box 14, the last flexible hold-down strip 15 that winds of being equipped with of spool, the tip that flexible hold-down strip 15 stretches out reel box 14 is equipped with dop 13, dop 13 and draw-in groove cooperation.

The adjusting shaft 9 comprises an outer cylinder 16 and an inner cylinder 17, the inner cylinder 17 is sleeved in the outer cylinder 16, a first spring 18 is arranged between the bottom surface of the outer cylinder 16 and the inner end of the inner cylinder 17, and the outer end of the inner cylinder 17 extends out of the outer cylinder 16; the side wall of the outer cylinder 16 is provided with a rectangular opening 19 at the position of the movable plate 6, an elastic clamping piece 20 protruding towards the movable plate is arranged in the rectangular opening 19, one end of the elastic clamping piece 20 is hinged to the side wall of the outer cylinder 16, the other end of the elastic clamping piece 20 can be retracted into the outer cylinder and provided with a fixed block, a sliding groove is formed in the inner side of the fixed block, a supporting vertical rod 21 is arranged in the sliding groove, one end of the supporting vertical rod 21 is in movable contact with the sliding groove, the other end of the supporting vertical rod 21 is fixed to the wall of the inner.

The elastic clamping mechanism comprises an upper transverse plate 26, a lower transverse plate 27, a clamping plate 28 and an elastic bolt 29, the clamping plate 28 is arranged between the upper transverse plate 26 and the lower transverse plate 27, the side edge of the same side of the upper transverse plate 26 and the lower transverse plate 27 is fixed with the vertical plate 5, the lower transverse plate 27 is provided with an inner threaded hole, the elastic bolt 29 is arranged on the inner threaded hole, the clamping plate 28 is fixedly arranged on the elastic bolt 29, the upper end of the elastic bolt 29 is flush with the upper edge of the clamping plate 28, the upper end of the elastic bolt 29 is provided with a downward deep hole 30, a pressing block 31, a first sliding rod 32, a third spring 33, a limiting block 34 and a limiting ring 35 are arranged in the deep hole 30, the pressing block 31 and the limiting block 34 are respectively arranged at the upper end and the lower end of the first sliding rod 32, the third spring 33 is sleeved on the first sliding rod; the vertical plate 5, the movable plate 6 and the arc-shaped positioning plate 7 are all provided with sterilization coatings.

Specifically, the restraint mold comprises a left positioning mechanism 3, a right positioning mechanism 4 and an elastic clamping mechanism which are oppositely arranged, so that the body position of a patient during radiotherapy can be accurately positioned, and the restraint mold is convenient to mount and use; can provide suitable external force restraint to patient's thorax position through elasticity compression band to can effectively restrain respiratory motion to the influence of tumour position change, improve the accuracy nature of radiotherapy and realize better treatment.

Left side positioning mechanism 3, right side positioning mechanism 4 all are equipped with riser 5, fly leaf 6, arc locating plate 7 and regulating spindle 9, and 5 lower parts of riser are fixed through elasticity fixture with the treatment bed side, and 5 upper portions of riser openly open there is the bar mouth 11, installs fly leaf 6 in the bar mouth 11, and fly leaf 6 shape and the cooperation of

bar mouth

11, and 5 upper portion sides of riser, fly leaf 6 sides all open there is the groove 12 that passes through of bar, can adjust the relative height of fly leaf 6 on riser 5 and the length that fly leaf 6 stretched into to the inboard through regulating spindle 9. 2 arc locating plate 7 sets up patient's health both sides relatively, then can provide external force through elasticity compressing band 15 to patient's health and fix to can avoid rocking of patient at the radiotherapy in-process, influence treatment. Because arc locating plate 7, elasticity compressing band 15 are all can dismantle, make things convenient for patient's position adjustment and have better assistance-localization real-time effect, produce decurrent extrusion to patient's health, produce the restraint to patient respiratory motion change, improve the degree of accuracy of treatment.

When in use, the treatment bed 2 is arranged on the base 1, and a three-dimensional movement mechanism can be arranged between the base 1 and the treatment bed 2 so as to realize that the movement during treatment meets the radiation field requirement of radiotherapy. The patient lies on the back on the treatment bed and preliminarily adjusts the body position of the patient, then the left positioning mechanism 3 and the right positioning mechanism 4 are respectively fixed with the two sides of the treatment bed 2 through the connecting mechanisms at the lower parts, then the adjusting shaft 9 is operated to separate the movable plate 6 from the strip-shaped opening 11 of the vertical plate 5, the movable plate is matched with the nut through the adjusting shaft to form fixed clamping with the vertical plate 5, the adjusting shaft is matched with the elastic clamping piece to be fixedly connected with the movable plate 6, at the moment, the movable plate 6 is in a state of being vertical to the vertical plate 5, and the arc-shaped positioning plate 7 is attached to the contact; in order to facilitate the operation, install the rotation handle 10 at regulating shaft 9 tip, still can set up the instruction line of regulating shaft 9 for riser 5 rotation angle on the rotation handle 10, with the accurate left side positioning mechanism 3 that realizes, right side positioning mechanism 4 keeps unified, can adjust the relative height of fly leaf 6 on riser 5 and the length that fly leaf 6 stretches into to the inboard through regulating shaft 9, to the accurate control that fly leaf 6 stretches into the length to inboard relative riser 5, thereby can realize the accurate positioning to patient's position, also can adapt to the location needs of different patient's bodily forms simultaneously.

As shown in fig. 9 and 10, in this embodiment, a through hole is formed in the center of the elastic clip, a movable post 22 is disposed in the through hole, a horizontal second spring 23 is mounted on the end of the movable post 22 located inside the elastic clip, and the inner end of the second spring 23 is fixed to the side wall of the outer cylinder 16; the connecting end of the movable column 22 and the second spring 23 is fixedly connected with a metal pull rope 24, the other end of the metal pull rope 24 penetrates through the side wall of the outer cylinder 16 and then is fixed with the lower part of the inner cylinder 17, and the pull rope is positioned below the supporting cross rod.

The movable column 22 is installed at the central part of the elastic clamping piece, the extrusion force between the adjusting shaft 9 and the movable plate 6 is increased, the transverse stability of the adjusting plate 6 is ensured, and in order to increase the friction force between the adjusting shaft 9 and the strip-shaped through groove wall of the

movable plate

6, 2 sets of elastic clamping pieces can be symmetrically arranged on the side wall of the outer cylinder 16.

Furthermore, in the present embodiment, a plurality of positioning holes are spaced apart from the inner wall of the strip-shaped through slot 12 of the movable plate 6, and the outer end of the movable column 22 can extend into the positioning holes; the through hole and the movable column 22 are both conical, and the diameter of the outer end of the movable column 22 is larger than that of the inner side of the through hole. Through the cooperation of a plurality of locating holes and activity post 22, can improve the rotational positioning of activity board 6 on the one hand, on the other hand also can increase the stability of being connected between regulating shaft 9 and the activity board 6.

As shown in fig. 7 and 8, the first spring 18 of the present embodiment is sleeved on a vertical guide rod 25, the lower end of the guide rod 25 is fixed with the inner bottom of the outer cylinder 16, and the upper end thereof extends into the inner cylinder 17. The guide rod 25 can ensure the accuracy of the movement of the inner cylinder 17 in the outer cylinder 16, especially can improve the positioning and matching performance of the sliding grooves on the end parts of the vertical support rod 21 and the elastic clamping piece, and ensures that the elastic clamping piece and the side wall of the sliding groove form better extrusion force.

The vertical plate 5, the movable plate 6 and the arc-shaped positioning plate 7 are all provided with the sterilization coating to improve the self-cleaning function of the existing body position fixing device and the treatment bed, and the raw materials for preparing the sterilization coating comprise the following components in parts by mass: 28-36 parts of alkyd resin, 70-90 parts of chlorinated rubber, 3-6 parts of lecithin, 8-10 parts of carboxymethyl cellulose, 30-35 parts of oxidized castor oil, 9-13 parts of calcium carbonate powder, 3-5 parts of benzene-terminated polyisobutylene, 6-8 parts of dodecyl alcohol ester, 2-5 parts of dimethyl azodiisobutyrate, Ag-CuO-MnO₂24-30 parts of composite bactericide, 12-16 parts of graphite fluoride, 5-9 parts of gelatin, 20 parts of propylene glycol40 parts of the components.

Example 1

The raw materials for preparing the bactericidal coating comprise the following components in parts by mass: 28 parts of alkyd resin, 70 parts of chlorinated rubber, 3 parts of lecithin, 8 parts of carboxymethyl cellulose, 30 parts of oxidized castor oil, 9 parts of calcium carbonate powder, 3 parts of benzene-terminated polyisobutylene, 6 parts of dodecyl alcohol ester, 2 parts of dimethyl azodiisobutyrate, 24 parts of Ag-CuO-MnO2 composite bactericide, 12 parts of graphite fluoride, 5 parts of gelatin and 20 parts of propylene glycol.

The preparation method of the Ag-CuO-MnO2 composite bactericide comprises the following steps: weighing copper nitrate and manganese sulfate, adding a proper amount of distilled water, mixing and stirring until the copper nitrate and the manganese sulfate are completely dissolved, then adding a urea solution and a sodium chlorate solution, mixing and stirring uniformly, adding the mixed solution into a high-pressure reaction kettle, heating to 120 ℃, keeping the temperature for 1h, heating to 140 ℃, keeping the temperature for 6h, filtering, washing, drying and grinding to obtain a CuO-MnO2 tubular composite material; mixing diatomite and attapulgite, grinding, sieving with a 200-mesh sieve, adding into an appropriate amount of acid solution, stirring at 60 deg.C for 2 hr, filtering, and washing to obtain mixed powder; adding distilled water into the mixed powder, performing ultrasonic dispersion, adding cobalt nitrate and N-methyl pyrrolidone, stirring, dissolving and dispersing uniformly, performing ultrasonic oscillation and stirring for 30min, rapidly injecting a sodium borohydride solution, stirring, dropwise adding a silver nitrate solution into the mixed solution, performing ultrasonic oscillation and stirring for 1h, adding a CuO-MnO2 tubular composite material and a proper amount of gelatin, and stirring at 60 +/-5 ℃ to completely dissolve the CuO-MnO2 tubular composite material and the gelatin to obtain a uniform colloidal mixed material; sealing and aging the colloidal mixed material for 6h, then adding excessive alcohol into the aged colloidal mixed material, filtering to obtain a gelatin-based sponge, placing the gelatin-based sponge into liquid nitrogen for quick freezing for 3min, freeze-drying, roasting at the high temperature of 500 ℃ for 6h, cooling to room temperature, grinding and crushing to obtain a mixed material; adding the mixed material into an acetone solution, uniformly dispersing, adding sorbic acid, stirring for 1h, filtering and drying to obtain the Ag-CuO-MnO2 composite bactericide, wherein in the prepared Ag-CuO-MnO2 composite bactericide, the mass ratio of Ag to CuO to MnO2 to diatomite to attapulgite is 2: 1: 0.8: 6: 8.

The preparation method of the bactericidal coating comprises the following steps:

(1) ultrasonically stirring and uniformly mixing oxidized castor oil, graphite fluoride and 1/3 parts by weight of benzene-terminated polyisobutylene to obtain a mixed material A;

(2) putting alkyd resin, chlorinated rubber, propylene glycol and lecithin into a reaction kettle, and mechanically stirring until the alkyd resin, the chlorinated rubber, the propylene glycol and the lecithin are completely and uniformly mixed to obtain a mixed material B;

(3) heating the mixed material B in the reaction kettle to 70 ℃, adding dimethyl azodiisobutyrate and the residual 2/3 parts by weight of benzene-terminated polyisobutylene, mechanically stirring for 30min, adding the Ag-CuO-MnO2 composite bactericide and calcium carbonate powder, and mechanically stirring for 6h to obtain a mixed material C;

(4) heating the mixed material C in the reaction kettle to 120 ℃, dropwise adding the mixed material A under the condition of mechanical stirring, and after dropwise adding is finished, continuously stirring for 6 hours at 120 ℃ to obtain a mixed material D;

(5) and cooling the mixed material D to 50 ℃, adding the carboxymethyl cellulose, the dodecyl alcohol ester and the gelatin, mechanically stirring until the carboxymethyl cellulose, the dodecyl alcohol ester and the gelatin are completely dissolved and uniformly dispersed, and cooling to room temperature to obtain the bactericidal coating.

Example 2

The raw materials for preparing the bactericidal coating comprise the following components in parts by mass: 32 parts of alkyd resin, 80 parts of chlorinated rubber, 5 parts of lecithin, 9 parts of carboxymethyl cellulose, 32 parts of oxidized castor oil, 11 parts of calcium carbonate powder, 4 parts of benzene-terminated polyisobutylene, 7 parts of dodecyl alcohol ester, 4 parts of dimethyl azodiisobutyrate, 27 parts of Ag-CuO-MnO2 composite bactericide, 14 parts of graphite fluoride, 7 parts of gelatin and 30 parts of propylene glycol.

The preparation method of the Ag-CuO-MnO2 composite bactericide comprises the following steps: weighing copper nitrate and manganese sulfate, adding a proper amount of distilled water, mixing and stirring until the copper nitrate and the manganese sulfate are completely dissolved, then adding a urea solution and a sodium chlorate solution, mixing and stirring uniformly, adding the mixed solution into a high-pressure reaction kettle, heating to 120 ℃ at the speed of 6-8 ℃/min, preserving heat for 1h, heating to 140 ℃ and preserving heat for 6h, filtering, washing, drying and grinding to obtain a CuO-MnO2 tubular composite material; mixing diatomite and attapulgite, grinding, sieving with a 200-mesh sieve, adding into an appropriate amount of acid solution, stirring at 60 deg.C for 2 hr, filtering, and washing to obtain mixed powder; adding distilled water into the mixed powder, performing ultrasonic dispersion, adding cobalt nitrate and N-methyl pyrrolidone, stirring, dissolving and dispersing uniformly, performing ultrasonic oscillation and stirring for 30min, rapidly injecting a sodium borohydride solution, dropwise adding a silver nitrate solution into the mixed solution, performing ultrasonic oscillation and stirring for 1h, adding a CuO-MnO2 tubular composite material and a proper amount of gelatin, and stirring at 60 +/-5 ℃ to completely dissolve the CuO-MnO2 tubular composite material and the gelatin to obtain a uniform colloidal mixed material; sealing and aging the colloidal mixed material for 8h, then adding excessive alcohol into the aged colloidal mixed material, filtering to obtain a gelatin-based sponge, placing the gelatin-based sponge into liquid nitrogen for quick freezing for 3min, freeze-drying, roasting at the high temperature of 500 ℃ for 6h, cooling to room temperature, grinding and crushing to obtain a mixed material; adding the mixed material into an acetone solution, uniformly dispersing, adding sorbic acid, stirring for 1h, filtering and drying to obtain the Ag-CuO-MnO2 composite bactericide, wherein in the prepared Ag-CuO-MnO2 composite bactericide, the mass ratio of Ag to CuO to MnO2 to diatomite to attapulgite is 3: 1.5: 0.8: 10: 8.

(3) heating the mixed material B in the reaction kettle to 70 ℃, adding dimethyl azodiisobutyrate and the residual 2/3 parts by weight of benzene-terminated polyisobutylene, mechanically stirring for 30min, adding the Ag-CuO-MnO2 composite bactericide and calcium carbonate powder, and mechanically stirring for 10h to obtain a mixed material C;

(4) heating the mixed material C in the reaction kettle to 120 ℃, dropwise adding the mixed material A under the condition of mechanical stirring, and after dropwise adding is finished, continuously stirring for 8 hours at 120 ℃ to obtain a mixed material D;

Example 3

The raw materials for preparing the bactericidal coating comprise the following components in parts by mass: 36 parts of alkyd resin, 90 parts of chlorinated rubber, 6 parts of lecithin, 10 parts of carboxymethyl cellulose, 35 parts of oxidized castor oil, 13 parts of calcium carbonate powder, 5 parts of benzene-terminated polyisobutylene, 8 parts of dodecyl alcohol ester, 5 parts of dimethyl azodiisobutyrate, 30 parts of Ag-CuO-MnO2 composite bactericide, 16 parts of graphite fluoride, 9 parts of gelatin and 40 parts of propylene glycol.

The preparation method of the Ag-CuO-MnO2 composite bactericide comprises the following steps: weighing copper nitrate and manganese sulfate, adding a proper amount of distilled water, mixing and stirring until the copper nitrate and the manganese sulfate are completely dissolved, then adding a urea solution and a sodium chlorate solution, mixing and stirring uniformly, adding the mixed solution into a high-pressure reaction kettle, heating to 120 ℃ at the speed of 6-8 ℃/min, preserving heat for 1h, heating to 140 ℃ and preserving heat for 6h, filtering, washing, drying and grinding to obtain a CuO-MnO2 tubular composite material; mixing diatomite and attapulgite, grinding, sieving with a 200-mesh sieve, adding into an appropriate amount of acid solution, stirring at 60 deg.C for 2 hr, filtering, and washing to obtain mixed powder; adding distilled water into the mixed powder, performing ultrasonic dispersion, adding cobalt nitrate and N-methyl pyrrolidone, stirring, dissolving and dispersing uniformly, performing ultrasonic oscillation and stirring for 30min, rapidly injecting a sodium borohydride solution, dropwise adding a silver nitrate solution into the mixed solution, performing ultrasonic oscillation and stirring for 1h, adding a CuO-MnO2 tubular composite material and a proper amount of gelatin, and stirring at 60 +/-5 ℃ to completely dissolve the CuO-MnO2 tubular composite material and the gelatin to obtain a uniform colloidal mixed material; sealing and aging the colloidal mixed material for 7h, then adding excessive alcohol into the aged colloidal mixed material, filtering to obtain a gelatin-based sponge, placing the gelatin-based sponge into liquid nitrogen for quick freezing for 3min, freeze-drying, roasting at the high temperature of 500 ℃ for 6h, cooling to room temperature, grinding and crushing to obtain a mixed material; adding the mixed material into an acetone solution, uniformly dispersing, adding sorbic acid, stirring for 1h, filtering and drying to obtain the Ag-CuO-MnO2 composite bactericide, wherein in the prepared Ag-CuO-MnO2 composite bactericide, the Ag-CuO-MnO2 composite bactericide comprises Ag, CuO, MnO2, kieselguhr and attapulgite in a mass ratio of 4: 2: 0.8: 8: 8.

(3) heating the mixed material B in the reaction kettle to 70 ℃, adding dimethyl azodiisobutyrate and the residual 2/3 parts by weight of benzene-terminated polyisobutylene, mechanically stirring for 30min, adding the Ag-CuO-MnO2 composite bactericide and calcium carbonate powder, and mechanically stirring for 8h to obtain a mixed material C;

Comparative example 1

The raw materials for preparing the bactericidal coating comprise the following components in parts by mass: 32 parts of alkyd resin, 80 parts of chlorinated rubber, 5 parts of lecithin, 9 parts of carboxymethyl cellulose, 32 parts of oxidized castor oil, 11 parts of calcium carbonate powder, 4 parts of benzene-terminated polyisobutylene, 7 parts of dodecyl alcohol ester, 4 parts of dimethyl azodiisobutyrate, 14 parts of graphite fluoride, 7 parts of gelatin and 30 parts of propylene glycol.

The preparation method of the bactericidal coating comprises the following steps: ultrasonically stirring and uniformly mixing oxidized castor oil, graphite fluoride and 1/3 parts by weight of benzene-terminated polyisobutylene to obtain a mixed material A; putting alkyd resin, chlorinated rubber, propylene glycol and lecithin into a reaction kettle, and mechanically stirring until the alkyd resin, the chlorinated rubber, the propylene glycol and the lecithin are completely and uniformly mixed to obtain a mixed material B; heating the mixed material B in the reaction kettle to 70 ℃, adding dimethyl azodiisobutyrate and the residual 2/3 parts by weight of benzene-terminated polyisobutylene, mechanically stirring for 30min, adding calcium carbonate powder, mechanically stirring for 10h, heating to 120 ℃, dropwise adding the mixed material A under the condition of mechanical stirring, after dropwise adding, continuously stirring for 8h at 120 ℃, cooling to 50 ℃, adding carboxymethyl cellulose, dodecyl alcohol ester and gelatin, mechanically stirring until complete dissolution and uniform dispersion, and cooling to room temperature to obtain the mechanical coating.

Comparative example 2

The raw materials for preparing the bactericidal coating comprise the following components in parts by mass: 32 parts of alkyd resin, 80 parts of chlorinated rubber, 5 parts of lecithin, 9 parts of carboxymethyl cellulose, 32 parts of oxidized castor oil, 11 parts of calcium carbonate powder, 4 parts of benzene-terminated polyisobutylene, 7 parts of dodecyl alcohol ester, 4 parts of dimethyl azodiisobutyrate, 27 parts of Ag composite bactericide, 14 parts of graphite fluoride, 7 parts of gelatin and 30 parts of propylene glycol.

The preparation method of the Ag composite bactericide comprises the following steps: mixing diatomite and attapulgite, grinding, sieving with a 200-mesh sieve, adding into an appropriate amount of acid solution, stirring at 60 deg.C for 2 hr, filtering, and washing to obtain mixed powder; adding distilled water into the mixed powder, performing ultrasonic dispersion, adding cobalt nitrate and N-methyl pyrrolidone, stirring, dissolving and dispersing uniformly, rapidly injecting a sodium borohydride solution under ultrasonic oscillation and stirring conditions, stirring for 30min, dropwise adding a silver nitrate solution into the mixed solution, performing ultrasonic oscillation and stirring for 1h, adding a proper amount of gelatin, and stirring at 60 +/-5 ℃ to completely dissolve the gelatin to obtain a uniform colloidal mixed material; sealing and aging the colloidal mixed material for 8h, then adding excessive alcohol into the aged colloidal mixed material, filtering to obtain a gelatin-based sponge, placing the gelatin-based sponge into liquid nitrogen for quick freezing for 3min, freeze-drying, roasting at the high temperature of 500 ℃ for 6h, cooling to room temperature, grinding and crushing to obtain a mixed material; and adding the mixed material into an acetone solution, uniformly dispersing, adding sorbic acid, stirring for 1h, filtering and drying to obtain the Ag composite bactericide, wherein the mass ratio of Ag to diatomite to attapulgite in the prepared Ag composite bactericide is 5: 10: 8.

The preparation method of the bactericidal coating comprises the following steps: ultrasonically stirring and uniformly mixing oxidized castor oil, graphite fluoride and 1/3 parts by weight of benzene-terminated polyisobutylene to obtain a mixed material A; putting alkyd resin, chlorinated rubber, propylene glycol and lecithin into a reaction kettle, and mechanically stirring until the alkyd resin, the chlorinated rubber, the propylene glycol and the lecithin are completely and uniformly mixed to obtain a mixed material B; heating the mixed material B in the reaction kettle to 70 ℃, adding dimethyl azodiisobutyrate and the residual 2/3 parts by weight of phenyl end group polyisobutylene, mechanically stirring for 30min, adding an Ag composite bactericide and calcium carbonate powder, mechanically stirring for 10h, heating to 120 ℃, dropwise adding the mixed material A under the condition of mechanical stirring, continuously stirring for 8h after dropwise adding, cooling to 50 ℃, adding carboxymethyl cellulose, dodecyl alcohol ester and gelatin, mechanically stirring until complete dissolution and uniform dispersion, and cooling to room temperature to obtain the bactericidal coating.

Comparative example 3

The raw materials for preparing the bactericidal coating comprise the following components in parts by mass: 32 parts of alkyd resin, 80 parts of chlorinated rubber, 5 parts of lecithin, 9 parts of carboxymethyl cellulose, 32 parts of oxidized castor oil, 11 parts of calcium carbonate powder, 4 parts of benzene-terminated polyisobutylene, 7 parts of dodecyl alcohol ester, 4 parts of dimethyl azodiisobutyrate, 27 parts of CuO-MnO2 composite bactericide, 14 parts of graphite fluoride, 7 parts of gelatin and 30 parts of propylene glycol.

The preparation method of the CuO-MnO2 composite bactericide comprises the following steps: weighing copper nitrate and manganese sulfate, adding a proper amount of distilled water, mixing and stirring until the copper nitrate and the manganese sulfate are completely dissolved, then adding a urea solution and a sodium chlorate solution, mixing and stirring uniformly, adding the mixed solution into a high-pressure reaction kettle, heating to 120 ℃ at the speed of 6-8 ℃/min, preserving heat for 1h, heating to 140 ℃ and preserving heat for 6h, filtering, washing, drying and grinding to obtain a CuO-MnO2 tubular composite material; mixing diatomite and attapulgite, grinding, sieving with a 200-mesh sieve, adding into an appropriate amount of acid solution, stirring at 60 deg.C for 2 hr, filtering, and washing to obtain mixed powder; adding distilled water into the mixed powder, performing ultrasonic dispersion, adding a CuO-MnO2 tubular composite material and a proper amount of gelatin, and stirring at 60 +/-5 ℃ to completely dissolve the CuO-MnO2 tubular composite material and the gelatin to obtain a uniform colloidal mixed material; sealing and aging the colloidal mixed material for 8h, then adding excessive alcohol into the aged colloidal mixed material, filtering to obtain a gelatin-based sponge, placing the gelatin-based sponge into liquid nitrogen for quick freezing for 3min, freeze-drying, roasting at the high temperature of 500 ℃ for 6h, cooling to room temperature, grinding and crushing to obtain a mixed material; adding the mixed material into an acetone solution, uniformly dispersing, adding sorbic acid, stirring for 1h, filtering and drying to obtain the CuO-MnO2 composite bactericide, wherein in the prepared CuO-MnO2 composite bactericide, the mass ratio of CuO, MnO2, kieselguhr and attapulgite is 4: 10: 8.

The preparation method of the bactericidal coating comprises the following steps: ultrasonically stirring and uniformly mixing oxidized castor oil, graphite fluoride and 1/3 parts by weight of benzene-terminated polyisobutylene to obtain a mixed material A; putting alkyd resin, chlorinated rubber, propylene glycol and lecithin into a reaction kettle, and mechanically stirring until the alkyd resin, the chlorinated rubber, the propylene glycol and the lecithin are completely and uniformly mixed to obtain a mixed material B; heating the mixed material B in a reaction kettle to 70 ℃, adding dimethyl azodiisobutyrate and the residual 2/3 parts by weight of benzene-terminated polyisobutylene, mechanically stirring for 30min, adding a CuO-MnO2 composite bactericide and calcium carbonate powder, mechanically stirring for 10h, heating to 120 ℃, dropwise adding the mixed material A under the condition of mechanical stirring, continuously stirring for 8h after dropwise adding is finished, cooling to 50 ℃, adding carboxymethyl cellulose, dodecyl alcohol ester and gelatin, mechanically stirring until the materials are completely dissolved and uniformly dispersed, and cooling to room temperature to obtain the bactericidal coating.

Comparative example 4

The preparation method of the Ag-CuO-MnO2 composite bactericide is the same as that of example 2.

The preparation method of the bactericidal coating comprises the following steps: putting alkyd resin, chlorinated rubber, propylene glycol, lecithin, oxidized castor oil, graphite fluoride and 1/3 parts by weight of benzene-terminated polyisobutylene into a reaction kettle, mechanically stirring until the mixture is completely and uniformly mixed, heating to 70 ℃, adding dimethyl azodiisobutyrate and the rest 2/3 parts by weight of benzene-terminated polyisobutylene, mechanically stirring for 30min, adding Ag-CuO-MnO2 composite bactericide and calcium carbonate powder, mechanically stirring for 10h, heating to 120 ℃, continuously stirring for 8h, cooling to 50 ℃, adding carboxymethyl cellulose, dodecyl alcohol ester and gelatin, mechanically stirring until the mixture is completely and uniformly dissolved and dispersed, and cooling to room temperature to obtain the bactericidal coating.

Comparative example 5

The raw materials for preparing the bactericidal coating comprise the following components in parts by mass: 32 parts of alkyd resin, 80 parts of chlorinated rubber, 5 parts of lecithin, 9 parts of carboxymethyl cellulose, 11 parts of calcium carbonate powder, 4 parts of benzene-terminated polyisobutylene, 7 parts of dodecyl alcohol ester, 4 parts of dimethyl azodiisobutyrate, 27 parts of Ag-CuO-MnO2 composite bactericide, 7 parts of gelatin and 30 parts of propylene glycol.

(1) putting alkyd resin, chlorinated rubber, benzene-terminated polyisobutylene, propylene glycol and lecithin into a reaction kettle, mechanically stirring until the alkyd resin, the chlorinated rubber, the benzene-terminated polyisobutylene, the propylene glycol and the lecithin are completely and uniformly mixed, heating to 70 ℃, adding dimethyl azodiisobutyrate, mechanically stirring for 30min, adding an Ag-CuO-MnO2 composite bactericide and calcium carbonate powder, mechanically stirring for 10h, cooling to 50 ℃, adding carboxymethyl cellulose, dodecyl alcohol ester and gelatin, mechanically stirring until the carboxymethyl cellulose, the dodecyl alcohol ester and the gelatin are completely dissolved and uniformly dispersed, and cooling to room temperature to obtain the bactericidal coating.

The bactericidal coatings prepared in examples 1 to 3 of the present invention and the coatings prepared in comparative examples 4 and 5 were respectively subjected to performance tests, and the test results are shown in table 1:

TABLE 1

Detecting items

Detection standard

Example 1

Example 2

Example 3

Ratio of 4

Comparative example 5

Hardness of

GB/T6739-2006

8H

7H

5H

Grade of adhesion

GB/T9286-1998

1

2

3

Time to surface dry

23min

20min

21min

29min

27min

Actual drying time

3h

4.5h

4h

Resistance to salt fog

GB/T1771-2007

286h

297h

294h

246h

221h

Impact resistance

GB/T1732-1993

63

65

61

53

45

anti-Escherichia coli ratio

JIS-Z-2801-2000

97.4%

98.3%

97.0%

97.2%

Anti-staphylococcus aureus rate

JIS-Z-2801-2000

99.2%

99.4%

98.9%

99.1%

99.2%

As can be seen from the data in Table 1, the bactericidal coating provided by the invention has good properties of hardness, adhesion, salt spray resistance, impact resistance and the like.

The bactericidal coatings prepared in examples 1-3 of the invention and the coatings prepared in comparative examples 1-3 are respectively subjected to bacteriostatic performance detection, the bactericidal performance of the coatings is detected by a bacteriostatic circle method, and the bactericidal performance of the coatings is reflected by a bactericidal test of staphylococcus aureus, wherein the detection method comprises the following steps:

1. experimental strains: staphylococcus aureus ATCC 6538.

2. And (3) strain culture medium: nutrient agar medium, nutrient broth medium.

3. The specific experimental steps are as follows:

(1) preparing the drug sensitive tablet: qualitative filter paper is made into round paper sheet with diameter of 6mm by puncher, and is autoclaved at 121 deg.C for 30min, and then cooled. Then respectively spraying the coatings of examples 1-3 and comparative examples 1-3 on one surface of a filter paper sheet by a spray gun under the aseptic condition for 0.5mm, drying to prepare a drug sensitive sheet, preparing 5 drug sensitive sheets for each coating, preparing 5 blank sterilized paper sheets as a control group, and sterilizing a culture dish, a measuring cylinder, a syringe, a puncher, distilled water, a culture medium and the like at 121 ℃ for 30 min;

(2) preparing a bacterial liquid: placing staphylococcus aureus strains in 10ml of nutrient broth culture medium, culturing at 37 ℃ for 18h, respectively taking 1ml of culture solution, adding 9ml of 0.9% sterile sodium chloride solution, and diluting the strain solution to 1.05 x 106cfu/ml by adopting a 10-time incremental dilution method for later use;

(3) putting a nutrient agar culture medium into a culture dish to prepare a planar nutrient agar culture medium, uniformly inoculating the bacterial liquid on the plane of the nutrient agar culture medium, paving the drug sensitive tablets on the surface of the culture medium, putting the culture dish into a biochemical incubator, culturing for 24 hours at constant temperature of 37 ℃, measuring the diameter of a bacteriostatic circle of each drug sensitive tablet, and calculating the average value of the diameters of the bacteriostatic circles of each group.

The results of the experiment are shown in table 2:

TABLE 2

Example 1

Example 2

Example 3

Comparative example 1

Comparative example 2

Comparative example 3

Control group

Diameter/mm of bacteriostatic circle

20

22

19

﹣

10

7

﹣

The experimental results show that the bactericidal coatings of the embodiments 1 to 3 have good bacteriostatic effect, and the bacteriostatic performance of the paint can be obviously improved by compounding the materials.

As shown in fig. 6, in this embodiment, in order to improve the connection stability of the elastic bolt 29 driving the clamping plate 28 and the upper cross plate 26 with the treatment couch 2, a second slide bar 36 is installed at the lower side of the limiting block 34, a fourth spring 37 is sleeved on the second slide bar 36, the upper end of the fourth spring 37 is fixed with the second slide bar 36, a boss 38 is arranged at the bottom of the deep hole 30, and the width of the boss 38 is located between the second slide bar 36 and the fourth spring 37. To facilitate the operation of the elastic bolt 29, a tightening knob 39 is mounted on the lower end of the elastic bolt.

The invention also discloses a use method of the dynamic tumor radiotherapy restraint mold, which comprises the restraint mold and comprises the following steps:

firstly, a patient lies on the back on the treatment bed 2 and the body position of the patient is preliminarily adjusted;

secondly, the left positioning mechanism 2 and the right positioning mechanism 3 are respectively and symmetrically arranged on two sides of the chest part of the patient through an elastic clamping mechanism;

operating the adjusting shaft 9 to separate the movable plate from the strip-shaped opening of the vertical plate 5, adjusting the height of the movable plate 6 on the vertical plate and the inward extending length of the movable plate, attaching the arc-shaped positioning plate 7 to the body contact part of the patient, and accurately positioning the body position of the patient;

and fourthly, pulling out the elastic compression belt 15 to enable the chuck to be matched with the clamping groove, and enabling the elastic compression belt 15 to restrain the chest part of the patient so as to control the displacement of the dynamic tumor along with the respiration and improve the accuracy of radiotherapy.

Particularly, the human body auxiliary positioning device comprises a treatment bed, and constraint molds arranged on two sides of the treatment bed, wherein each constraint mold comprises a left positioning mechanism 3, a right positioning mechanism 4 and an elastic clamping mechanism which are oppositely arranged, so that the body position of a patient during radiotherapy can be accurately positioned, and the human body auxiliary positioning device is convenient to install and use; can provide suitable external force restraint to patient's thorax position through elasticity compression band to can effectively restrain respiratory motion to the influence of tumour position change, improve the accuracy nature of radiotherapy and realize better treatment. Left side positioning mechanism 3, right side positioning mechanism 4 all are equipped with riser 5, fly leaf 6, arc locating plate 7 and regulating spindle 9, and 5 lower parts of riser are fixed through elasticity fixture with the treatment bed side, and 5 upper portions of riser openly open there is the bar mouth 11, installs fly leaf 6 in the bar mouth 11, and fly leaf 6 shape and the cooperation of

bar mouth

When the device is used, a patient lies on the back of a treatment bed 2 and preliminarily adjusts the body position of the patient, then the left positioning mechanism 3 and the right positioning mechanism 4 are respectively fixed with two sides of the treatment bed 2 through the connecting mechanisms at the lower parts, then the movable plate 6 is separated from the strip-shaped opening 11 of the vertical plate 5 by operating the adjusting shaft 9, the adjusting shaft is matched with the nut to form fixed clamping with the vertical plate 5, the adjusting shaft is matched with the elastic clamping piece to be fixedly connected with the movable plate 6, at the moment, the movable plate 6 is in a state of being vertical to the vertical plate 5, and the arc-shaped positioning plate 7 is attached to the contact part of; in order to facilitate the operation, install the rotation handle 10 at regulating shaft 9 tip, still can set up the instruction line of regulating shaft 9 for riser 5 rotation angle on the rotation handle 10, with the accurate left side positioning mechanism 3 that realizes, right side positioning mechanism 4 keeps unified, can adjust the relative height of fly leaf 6 on riser 5 and the length that fly leaf 6 stretches into to the inboard through regulating shaft 9, to the accurate control that fly leaf 6 stretches into the length to inboard relative riser 5, thereby can realize the accurate positioning to patient's position, also can adapt to the location needs of different patient's bodily forms simultaneously.

The technical contents not described in detail in the present invention are all known techniques.

Claims

1. A human body auxiliary positioning device for radiotherapy is characterized by comprising a treatment bed, wherein constraint molds are arranged on two sides of the treatment bed and comprise a left positioning mechanism and a right positioning mechanism which are oppositely arranged, the left positioning mechanism and the right positioning mechanism are respectively provided with a vertical plate, a movable plate, an arc-shaped positioning plate and an adjusting shaft, and the lower part of the vertical plate is provided with an elastic clamping mechanism connected with the edge of the treatment bed; the front surface of the upper part of the vertical plate is provided with a strip-shaped opening, a movable plate is arranged in the strip-shaped opening, the shape of the movable plate is matched with the strip-shaped opening, strip-shaped through grooves are formed in the side surface of the upper part of the vertical plate and the side surface of the movable plate, a positioning nut is arranged after an adjusting shaft sequentially penetrates through the strip-shaped through grooves of the vertical plate and the movable plate, and the relative height of the movable plate on the vertical plate and the length of the movable; the arc-shaped positioning plate is arranged on the front side of the inner end of the movable plate, the arc-shaped positioning plate and the movable plate are movably mounted through a connecting rod, a clamping block is mounted at the upper end of the arc-shaped positioning plate of the left positioning mechanism, a clamping groove is formed in the clamping block, a reel box is mounted at the upper end of the arc-shaped positioning plate of the right positioning mechanism, a reel is mounted in the reel box, an elastic pressing belt is wound on the reel, a clamping head is arranged at the end part of the elastic pressing belt extending out of the reel box; the adjusting shaft comprises an outer cylinder and an inner cylinder, the inner cylinder is sleeved in the outer cylinder, a first spring is arranged between the bottom surface of the outer cylinder and the inner end of the inner cylinder, and the outer end of the inner cylinder extends out of the outer cylinder; the side wall of the outer barrel is provided with a rectangular opening at the position of the movable plate, an elastic clamping piece protruding towards the movable plate is installed in the rectangular opening, one end of the elastic clamping piece is hinged with the side wall of the outer barrel, the other end of the elastic clamping piece can be retracted into the outer barrel and provided with a fixed block, a sliding groove is formed in the inner side of the fixed block, a supporting vertical rod is arranged in the sliding groove, one end of the supporting vertical rod is movably contacted with the sliding groove, the other end of the supporting vertical rod is fixed with the inner barrel wall; the elastic clamping mechanism comprises an upper transverse plate, a lower transverse plate, a clamping plate and an elastic bolt, wherein the clamping plate is arranged between the upper transverse plate and the lower transverse plate, and the upper transverse plate and the lower transverse plate are arrangedThe side edge of the same side is fixed with the vertical plate, an inner screw hole is formed in the lower transverse plate, an elastic bolt is installed in the inner screw hole, the clamping plate is fixedly installed on the elastic bolt, the upper end of the elastic bolt is flush with the upper edge of the clamping plate, a downward deep hole is formed in the upper end of the elastic bolt, a pressing block, a first sliding rod, a third spring, a limiting block and a limiting ring are installed in the deep hole, the pressing block and the limiting block are installed at the upper end and the lower end of the first sliding rod respectively, the third spring is sleeved on the first sliding rod, the limiting ring is arranged between the lower end of the third spring and the limiting; the vertical plate, the movable plate and the arc-shaped positioning plate are all provided with a sterilization coating, and the raw materials for preparing the sterilization coating comprise the following components in parts by mass: 28-36 parts of alkyd resin, 70-90 parts of chlorinated rubber, 3-6 parts of lecithin, 8-10 parts of carboxymethyl cellulose, 30-35 parts of oxidized castor oil, 9-13 parts of calcium carbonate powder, 3-5 parts of benzene-terminated polyisobutylene, 6-8 parts of dodecyl alcohol ester, 2-5 parts of dimethyl azodiisobutyrate, Ag-CuO-MnO₂24-30 parts of composite bactericide, 12-16 parts of graphite fluoride, 5-9 parts of gelatin and 20-40 parts of propylene glycol.

2. The auxiliary positioning device for the human body for radiotherapy according to claim 1, wherein the sterilization coating is made of the following raw materials in parts by mass: 28 parts of alkyd resin, 70 parts of chlorinated rubber, 3 parts of lecithin, 8 parts of carboxymethyl cellulose, 30 parts of oxidized castor oil, 9 parts of calcium carbonate powder, 3 parts of benzene-terminated polyisobutylene, 6 parts of dodecyl alcohol ester, 2 parts of dimethyl azodiisobutyrate, and Ag-CuO-MnO₂24 parts of composite bactericide, 12 parts of graphite fluoride, 5 parts of gelatin and 20 parts of propylene glycol.

3. The auxiliary positioning device for the human body for radiotherapy according to claim 1, wherein the sterilization coating is made of the following raw materials in parts by mass: 32 parts of alkyd resin, 80 parts of chlorinated rubber, 5 parts of lecithin, 9 parts of carboxymethyl cellulose, 32 parts of oxidized castor oil, 11 parts of calcium carbonate powder, 4 parts of benzene-terminated polyisobutylene, 7 parts of dodecyl alcohol ester, 4 parts of dimethyl azodiisobutyrate, and Ag-CuO-MnO₂27 parts of composite bactericide, 14 parts of graphite fluoride, 7 parts of gelatin and 3 parts of propylene glycol0 part of (A).

4. The auxiliary human positioning device for radiotherapy according to any one of claims 1 to 3, wherein the Ag-CuO-MnO is₂The preparation method of the composite bactericide comprises the following steps:

5. The auxiliary positioning device for radiotherapy as claimed in claim 1, wherein the elastic clip has a through hole at its center, a movable post is disposed in the through hole, a horizontal second spring is mounted on the end of the movable post inside the elastic clip, and the inner end of the second spring is fixed to the sidewall of the outer cylinder; the connecting end of the movable column and the second spring is fixedly connected with a metal pull rope, the other end of the metal pull rope penetrates through the side wall of the outer barrel and then is fixed with the lower portion of the inner barrel, and the pull rope is located below the supporting cross rod.

6. The auxiliary positioning device for radiotherapy as claimed in claim 5, wherein the inner wall of the strip-shaped through slot of the movable plate is provided with a plurality of positioning holes at intervals, and the outer end of the movable column can extend into the positioning holes; the through hole and the movable column are both conical, and the diameter of the outer end of the movable column is larger than that of the inner side of the through hole.

7. The auxiliary positioning device for radiotherapy as claimed in claim 1, wherein said elastic clip is symmetrically provided with 2 sets on the side wall of the outer cylinder; the first spring sleeve is arranged on the vertical guide rod in a sleeved mode, the lower end of the guide rod is fixed to the inner bottom of the outer cylinder, and the upper end of the guide rod extends into the inner cylinder.

8. The auxiliary positioning device for radiotherapy as claimed in claim 1, wherein a second slide bar is mounted under the limiting block, a fourth spring is sleeved on the second slide bar, the upper end of the fourth spring is fixed to the second slide bar, the bottom of the deep hole is a boss, and the width of the boss is between the second slide bar and the fourth spring.

9. A method for using the human body auxiliary positioning device for radiotherapy, which is characterized in that the human body auxiliary positioning device for radiotherapy comprises the human body auxiliary positioning device for radiotherapy according to any one of claims 1-3 and 5-8, and the use method thereof comprises the following steps:

(1) the patient lies on the back on the treatment bed and the body position of the patient is preliminarily adjusted;

(2) the left positioning mechanism and the right positioning mechanism are respectively and symmetrically arranged on two sides of the thoracic cavity part of the patient through the elastic clamping mechanism;

(3) the adjusting shaft is operated to separate the movable plate from the strip-shaped opening of the vertical plate, the height of the movable plate on the vertical plate and the length of the movable plate extending inwards are adjusted, the arc-shaped positioning plate is attached to the contact part of the body of the patient, and the body position of the patient is accurately positioned;

(4) the elastic compression band is pulled out to enable the chuck to be matched with the clamping groove, and the elastic compression band restrains the thoracic cavity part of the patient so as to control the displacement of the dynamic tumor along with the respiration and improve the accuracy of radiotherapy.