CN108779157B - 新α-1-微球蛋白衍生蛋白及其应用 - Google Patents

新α-1-微球蛋白衍生蛋白及其应用 Download PDF

Info

Publication number
CN108779157B
CN108779157B CN201780018244.4A CN201780018244A CN108779157B CN 108779157 B CN108779157 B CN 108779157B CN 201780018244 A CN201780018244 A CN 201780018244A CN 108779157 B CN108779157 B CN 108779157B
Authority
CN
China
Prior art keywords
glu
thr
gly
lys
asp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201780018244.4A
Other languages
English (en)
Chinese (zh)
Other versions
CN108779157A (zh
Inventor
勒纳·韦斯特·罗森洛夫
安纳莉·爱德斯特罗姆·黑格尔瓦尔
布·阿克尔斯特罗姆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guardian Medical International
Original Assignee
Guardian Medical International
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guardian Medical International filed Critical Guardian Medical International
Publication of CN108779157A publication Critical patent/CN108779157A/zh
Application granted granted Critical
Publication of CN108779157B publication Critical patent/CN108779157B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4717Plasma globulins, lactoglobulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
CN201780018244.4A 2016-03-18 2017-03-17 新α-1-微球蛋白衍生蛋白及其应用 Active CN108779157B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201670158 2016-03-18
DKPA201670158 2016-03-18
PCT/EP2017/056436 WO2017158181A1 (en) 2016-03-18 2017-03-17 Novel alpha-1-microglobulin derived proteins and their use

Publications (2)

Publication Number Publication Date
CN108779157A CN108779157A (zh) 2018-11-09
CN108779157B true CN108779157B (zh) 2022-12-30

Family

ID=56080208

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780018244.4A Active CN108779157B (zh) 2016-03-18 2017-03-17 新α-1-微球蛋白衍生蛋白及其应用

Country Status (15)

Country Link
US (1) US10981963B2 (enExample)
EP (1) EP3430032B1 (enExample)
JP (1) JP6976579B2 (enExample)
KR (1) KR102437662B1 (enExample)
CN (1) CN108779157B (enExample)
AU (1) AU2017235608B2 (enExample)
BR (1) BR112018068522A2 (enExample)
CA (1) CA3017836A1 (enExample)
EA (1) EA039776B1 (enExample)
ES (1) ES2896734T3 (enExample)
MX (1) MX2018011193A (enExample)
NZ (1) NZ746677A (enExample)
SG (1) SG11201807352XA (enExample)
WO (1) WO2017158181A1 (enExample)
ZA (1) ZA201805797B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111511386A (zh) * 2017-11-03 2020-08-07 卫士医疗国际公司 α-1-微球蛋白用于保护骨髓细胞的用途
WO2024165674A1 (en) 2023-02-08 2024-08-15 Guard Therapeutics International AB Alpha-1-microglobulin derived peptide fragments and uses thereof
US12227343B2 (en) * 2023-03-17 2025-02-18 Blue Buffalo Enterpises, Inc. Retail ready opening feature for e-commerce carton

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010006809A2 (en) * 2008-07-18 2010-01-21 Akerstroem Bo Medical use of the radical scavenger and antioxidant alpha-1-microglobulin
WO2014047490A1 (en) * 2012-09-21 2014-03-27 Beintoo, S.P.A. Interactive experience fully contained within an expandalble embedded unit

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013113851A1 (en) * 2012-01-31 2013-08-08 Technische Universitaet Muenchen Muteins of a1m lipocalin and method of production therefor
ES2599034T3 (es) * 2012-09-05 2017-01-31 A1M Pharma Ab Alfa-1-microglobulina para su uso en el tratamiento de enfermedades relacionadas con mitocondrias
US10226570B2 (en) * 2017-03-10 2019-03-12 Seton Healthcare Family Apparatus and method for temporarily securing a movable accessory device relative to a movable patient

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010006809A2 (en) * 2008-07-18 2010-01-21 Akerstroem Bo Medical use of the radical scavenger and antioxidant alpha-1-microglobulin
WO2014047490A1 (en) * 2012-09-21 2014-03-27 Beintoo, S.P.A. Interactive experience fully contained within an expandalble embedded unit

Also Published As

Publication number Publication date
SG11201807352XA (en) 2018-09-27
ES2896734T3 (es) 2022-02-25
WO2017158181A1 (en) 2017-09-21
JP2019519466A (ja) 2019-07-11
NZ746677A (en) 2023-02-24
EP3430032A1 (en) 2019-01-23
US10981963B2 (en) 2021-04-20
BR112018068522A2 (pt) 2019-01-22
US20190161524A1 (en) 2019-05-30
EA201892085A1 (ru) 2019-02-28
KR102437662B1 (ko) 2022-08-29
EP3430032B1 (en) 2021-09-01
EA039776B1 (ru) 2022-03-11
CN108779157A (zh) 2018-11-09
ZA201805797B (en) 2022-03-30
CA3017836A1 (en) 2017-09-21
AU2017235608A1 (en) 2018-10-18
MX2018011193A (es) 2019-03-28
JP6976579B2 (ja) 2021-12-08
KR20180127411A (ko) 2018-11-28
AU2017235608B2 (en) 2020-10-22

Similar Documents

Publication Publication Date Title
Ishikawa et al. A substrate preference for the rough endoplasmic reticulum resident protein FKBP22 during collagen biosynthesis
CN108779157B (zh) 新α-1-微球蛋白衍生蛋白及其应用
DK2900254T3 (en) ALFA-1 MICROGLOBULIN TO USE IN THE TREATMENT OF MITOCONDRY-RELATED DISEASES
JP2003515338A (ja) 補体結合酵素、masp−3、及びその使用
US20170000851A1 (en) Ptd-smad7 therapeutics
Yang et al. Decorin is a Zn2+ metalloprotein
JP2015504417A (ja) ジンジパイン阻害プロペプチド
AU2003234066B2 (en) Muteins of placental growth factor type 1, preparation method and application thereof
KR20130132375A (ko) 신장 증후군 및 관련 질환을 치료하는 방법
CA2247998C (en) Fragments of cr1 and their use
JP2006515168A (ja) 細胞におけるペルオキシソームカタラーゼ機能の促進
JP2006515168A5 (enExample)
CN120712100A (zh) α-1-微球蛋白衍生的肽片段及其用途
EP2404613B1 (en) Novel uses of fibrinogen-420 and active domain thereof
Ahmed Investigation into the Structure and Function of Hsp47
HK1210585B (en) Alpha-1-microglobulin for use in the treatment of mitochondria-related diseases

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
CB02 Change of applicant information

Address after: Lund, Sweden

Applicant after: Guardian Medical International

Address before: Lund, Sweden

Applicant before: A1M PHARMA AB

CB02 Change of applicant information
CB02 Change of applicant information

Address after: Stockholm, SWE

Applicant after: Guardian Medical International

Address before: Longde, Sweden

Applicant before: Guardian Medical International

CB02 Change of applicant information
GR01 Patent grant
GR01 Patent grant