CN108753614A - Anti-tumor experiment tumor cell culture device - Google Patents
Anti-tumor experiment tumor cell culture device Download PDFInfo
- Publication number
- CN108753614A CN108753614A CN201810648319.3A CN201810648319A CN108753614A CN 108753614 A CN108753614 A CN 108753614A CN 201810648319 A CN201810648319 A CN 201810648319A CN 108753614 A CN108753614 A CN 108753614A
- Authority
- CN
- China
- Prior art keywords
- incubator
- tumor
- cell culture
- tumor cell
- air
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
- C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/08—Flask, bottle or test tube
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/48—Holding appliances; Racks; Supports
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/02—Stirrer or mobile mixing elements
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Sustainable Development (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Molecular Biology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention discloses a kind of anti-tumor experiment tumor cell culture devices, driving gear rotation is driven by first motor, driving gear drives driven gear to rotate and then drives tray rotation, so as to carry out uniform, stable rock to the culture solution in culture bottle, the stirring blade in Primary culture bottle further can carry out uniform stirring to culture solution simultaneously, reduce the labor intensity of medical worker, inspection result error caused by rocking unevenness is avoided the occurrence of simultaneously, the temperature and humidity in babinet also can accurately be regulated and controled automatically.In the upper end of biochemical cultivation case, air-borne bacteria detector is set, by air-borne bacteria detector to the detection case of bacterium situation in air, control the watt level of ultraviolet germicidal, it can be when bacterium be all right in air in biochemical cultivation case, the operating power for reducing ultraviolet germicidal, effectively reduces the energy consumption of biochemical cultivation case.
Description
Technical field
Heating, drying field after being scrubbed the present invention relates to material block, more particularly to a kind of neodymium iron boron material block heating device.
Background technology
Tumour has become the present mankind and is most difficult to one of disease cured, and culture tumour cell is increased, and there is early stage to send out
The specific function of existing cell carcinogenesis, it is the key enzyme for controlling cell carcinogenesis proliferation that tumour cell, which increases, is the important of tumour growth
Factor wants early prevention treatment that tumour is avoided to be formed, it is necessary to precognition Tumor Growth is carried out by cell culture in blood,
When handling cell, needs to be sent into laboratory and be cultivated, test cell growth course and lesion need medical matters in incubation
Personnel rock culture dish inner cell, allow cell homoepitaxial, since the inevitable strength of manual operation is uneven, to examining later
Operation causes error；So needing a kind of automatic culture apparatus rocked.
Invention content
The object of the present invention is to provide a kind of anti-tumor experiment tumor cell culture devices, to solve above-mentioned background technology
The problem of middle proposition.
The present invention provides a kind of anti-tumor experiment tumor cell culture device, including incubator, on the incubator
Portion is hatch frame, and supporting rack is provided in incubator, and tray is equipped on support frame as described above, and the center of the tray is set
It is equipped with driving gear and driven gear, is meshed between the driving gear and driven gear, the centre bore of the driving gear
On be vertically installed with the first rotary shaft, the lower end of first rotary shaft passes through supporting rack and is being cultivated by shaft coupling with being arranged
The output axis connection of first motor in case inner bottom surface；It is provided with several grooves on the tray, is put in the groove
It is equipped with culture bottle, the culture bottle is provided centrally with the second rotary shaft, and the lower end of second rotary shaft is provided with paddle
Piece, upper end pass through culture bottle bottle cap and with the output axis connection for the second motor being arranged on bottle cap；In the incubator also
It is provided with temperature sensor, humidity sensor, heating module, refrigeration module and air-borne bacteria detector；The temperature sensor,
Humidity sensor and air-borne bacteria detector are connect with the input terminal for the controller being arranged on the outside of incubator respectively；It is described to add
Thermal modules, refrigeration module are connect with the output end of controller respectively；The top of the incubator is equipped with case lid, the case lid
Bottom surface is provided with air-filtering membrane.
Preferably, the center of the tray offers elliptical aperture, serrated slot, institute are provided on the side wall of elliptical aperture
It states on the left of driving gear and is engaged respectively with serrated slot on the right side of driven gear.
Preferably, the bottom surface inside the incubator is provided with crash roll, the first motor is arranged in the crash roll
On.
Preferably, being provided with fixture on the tray, the fixture is for fixing culture bottle.
Preferably, being fixed by connecting rod between several described culture bottles.
Preferably, being provided with ultraviolet germicidal in the incubator.
Preferably, support frame as described above bottom surface both side is respectively arranged with a strut, the one end of the strut far from supporting rack
It is arranged on the bottom surface inside incubator.
Preferably, the bottom surface of the incubator is provided with feet.
The beneficial effects of the invention are as follows：
A kind of anti-tumor experiment tumor cell culture device provided by the invention, driving gear is driven by first motor
Rotation, driving gear drive driven gear rotate so that drive tray rotation, so as to the culture solution in culture bottle into
Row uniformly, stablize rock, while the stirring blade in Primary culture bottle can further to culture solution carry out uniform stirring, subtract
The labor intensity of few medical worker, while avoiding the occurrence of inspection result error caused by rocking unevenness, temperature in babinet and wet
Degree also can accurately be regulated and controled automatically.Air-borne bacteria detector is set in the upper end of biochemical cultivation case, is examined by air-borne bacteria
Instrument is surveyed to the detection case of bacterium situation in air, controls the watt level of ultraviolet germicidal, it can be hollow in biochemical cultivation case
When bacterium is all right in gas, the operating power of ultraviolet germicidal is reduced, effectively reduces the energy consumption of biochemical cultivation case.
Description of the drawings
Fig. 1 is anti-tumor experiment tumor cell culture apparatus structure schematic diagram provided by the invention；
Fig. 2 is tray schematic diagram；
Fig. 3 is culture bottle schematic diagram；
Fig. 4 is System Control Figure.
Reference sign：
1, incubator；2, supporting rack；3, tray；4, serrated slot；5, driving gear；6, driven gear；7, groove；8,
One motor；9, crash roll；10, the first rotary shaft；11, fixture；12, culture bottle；13, the second rotary shaft；14, the second motor；15,
Stirring blade；16, connecting rod；17, temperature sensor；18, humidity sensor；19, heating module；20, refrigeration module；21, air
Detecting bacterium；22, ultraviolet germicidal；23, case lid；24, air-filtering membrane；25, fastening bolt；26, liquid crystal display；27,
Strut；28, feet.
Specific implementation mode
Below in conjunction with the accompanying drawings, the specific embodiment of the present invention is described in detail, it is to be understood that of the invention
Protection domain be not restricted by specific implementation.
As shown in Figs 1-4, an embodiment of the present invention provides a kind of anti-tumor experiment tumor cell culture devices, including training
Case 1 is supported, 1 top of incubator is hatch frame, is provided with supporting rack 2 in incubator 1, tray 3 is equipped on supporting rack 2, is set
Object disk 3 is provided centrally with driving gear 5 and driven gear 6, is meshed between driving gear 5 and driven gear 6, driving gear
Be vertically installed with the first rotary shaft 10 on 5 centre bore, the lower end of the first rotary shaft 10 pass through supporting rack 2 and by shaft coupling with
The output axis connection of first motor 8 in 1 inner bottom surface of incubator is set；Several grooves 7 are provided on tray 3, it is recessed
Culture bottle 12 is placed in slot 7, culture bottle 12 is provided centrally with the second rotary shaft 13, and the lower end of the second rotary shaft 13 is provided with
Stirring blade 15, upper end pass through culture bottle 12 bottle cap and with the output axis connection for the second motor 14 being arranged on bottle cap；Training
It supports and is additionally provided with temperature sensor 17, humidity sensor 18, heating module 19, refrigeration module 20 and air-borne bacteria detection in case 1
Device 21；Temperature sensor 17, humidity sensor 18 and air-borne bacteria detector 21 respectively with the control that is arranged on the outside of incubator 1
The input terminal of device processed connects；Heating module 19, refrigeration module 20 are connect with the output end of controller respectively；Further, described
Controller is connect with the liquid crystal display being arranged on incubator；The top of incubator 1 is equipped with case lid 23, specifically, case lid
23 both sides are fixed on by fastening bolt on incubator, and the bottom surface of case lid 23 is provided with air-filtering membrane 24.
In embodiments of the present invention, the center of tray 3 offers elliptical aperture, and saw is provided on the side wall of elliptical aperture
Tooth socket 4,5 left side of driving gear and 6 right side of driven gear are engaged with serrated slot 4 respectively.Bottom surface inside incubator 1 is provided with anti-
Pad 9 is shaken, first motor 8 is arranged on crash roll 9.Fixture 11 is provided on tray 3, fixture 11 is for fixing culture bottle 12.
It is fixed by connecting rod 16 between several culture bottles 12.Ultraviolet germicidal 22 is provided in incubator 1.2 bottom surface both side of supporting rack
It is respectively arranged with a strut 27, the one end of strut 27 far from supporting rack 2 is arranged on the bottom surface inside incubator 1.Incubator 1
Bottom surface be provided with feet 28.
In conclusion a kind of anti-tumor experiment tumor cell culture device provided in an embodiment of the present invention, passes through first
Motor drives driving gear rotation, and driving gear drives driven gear to rotate and then drives tray rotation, so as to training
Support bottle in culture solution carry out uniformly, stablize rock, while the stirring blade in Primary culture bottle can further to culture
Liquid carries out uniform stirring, reduces the labor intensity of medical worker, while avoiding the occurrence of inspection result error caused by rocking unevenness,
Temperature and humidity in babinet also can accurately be regulated and controled automatically.In the upper end of biochemical cultivation case, setting air-borne bacteria detects
Instrument controls the watt level of ultraviolet germicidal by air-borne bacteria detector to the detection case of bacterium situation in air, can
When bacterium is all right in air in biochemical cultivation case, the operating power of ultraviolet germicidal is reduced, biochemical culture is effectively reduced
The energy consumption of case.
Disclosed above is only several specific embodiments of the present invention, and still, the embodiment of the present invention is not limited to this, is appointed
What what those skilled in the art can think variation should all fall into protection scope of the present invention.
Claims (8)
1. anti-tumor experiment tumor cell culture device, including incubator (1), which is characterized in that incubator (1) top
For hatch frame, incubator (1) is interior to be provided with supporting rack (2), and tray (3), the glove are equipped on support frame as described above (2)
Disk (3) is provided centrally with driving gear (5) and driven gear (6), phase between the driving gear (5) and driven gear (6)
Engagement, is vertically installed with the first rotary shaft (10) on the centre bore of the driving gear (5), under first rotary shaft (10)
It holds across supporting rack (2) and is connected by shaft coupling and the output shaft for the first motor (8) being arranged in incubator (1) inner bottom surface
It connects；
It is provided with several grooves (7) on the tray (3), culture bottle (12), the culture are placed in the groove (7)
Bottle (12) is provided centrally with the second rotary shaft (13), and the lower end of second rotary shaft (13) is provided with stirring blade (15),
Upper end pass through culture bottle (12) bottle cap and with the output axis connection for the second motor (14) being arranged on bottle cap；
Temperature sensor (17), humidity sensor (18), heating module (19), refrigeration mould are additionally provided in the incubator (1)
Block (20) and air-borne bacteria detector (21)；The temperature sensor (17), humidity sensor (18) and air-borne bacteria detector
(21) it is connect respectively with the input terminal for the controller being arranged on incubator (1) outside；The heating module (19), refrigeration module
(20) it is connect respectively with the output end of controller；
The top of the incubator (1) is equipped with case lid (23), and the bottom surface of the case lid (23) is provided with air-filtering membrane (24).
2. anti-tumor experiment as described in claim 1 tumor cell culture device, which is characterized in that the tray (3)
Center offer elliptical aperture, serrated slot (4), the driving gear (5) and driven tooth are provided on the side wall of elliptical aperture
Wheel (6) is engaged with serrated slot (4) respectively.
3. anti-tumor experiment as described in claim 1 tumor cell culture device, which is characterized in that the incubator (1)
Internal bottom surface is provided with crash roll (9), and the first motor (8) is arranged on the crash roll (9).
4. anti-tumor experiment as described in claim 1 tumor cell culture device, which is characterized in that the tray (3)
On be provided with fixture (11), the fixture (11) is for fixing culture bottle (12).
5. anti-tumor experiment as claimed in claim 4 tumor cell culture device, which is characterized in that the culture bottle (12)
It is fixed by connecting rod (16) between culture bottle (12).
6. anti-tumor experiment as described in claim 1 tumor cell culture device, which is characterized in that the incubator (1)
Inside it is provided with ultraviolet germicidal (22).
7. anti-tumor experiment as described in claim 1 tumor cell culture device, which is characterized in that support frame as described above (2)
Bottom surface both side is respectively arranged with a strut (27), and the one end of the strut (27) far from supporting rack (2) is arranged in incubator (1)
On internal bottom surface.
8. anti-tumor experiment as described in claim 1 tumor cell culture device, which is characterized in that the incubator (1)
Bottom surface be provided with feet (28).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810648319.3A CN108753614A (en) | 2018-06-22 | 2018-06-22 | Anti-tumor experiment tumor cell culture device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810648319.3A CN108753614A (en) | 2018-06-22 | 2018-06-22 | Anti-tumor experiment tumor cell culture device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108753614A true CN108753614A (en) | 2018-11-06 |
Family
ID=63976493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810648319.3A Pending CN108753614A (en) | 2018-06-22 | 2018-06-22 | Anti-tumor experiment tumor cell culture device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108753614A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111423976A (en) * | 2020-04-10 | 2020-07-17 | 太原师范学院 | Aseptic inoculation device of microorganism |
| CN111735908A (en) * | 2020-05-06 | 2020-10-02 | 安徽科技学院 | Device and method for batch identification of wheat salt tolerance |
| CN113583869A (en) * | 2021-07-13 | 2021-11-02 | 杨金山 | Tumor cell culture device convenient to store and take |
| CN117264767A (en) * | 2023-11-10 | 2023-12-22 | 广州维柏生物科技有限公司 | Cell amplification incubator for gene detection |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013129558A1 (en) * | 2012-02-29 | 2013-09-06 | 株式会社ジェイテック | Cell culture device having culture medium replacement function |
| CN205528837U (en) * | 2016-04-14 | 2016-08-31 | 中国人民解放军第四军医大学 | Antitumor cell culture device for immunity |
| CN206956060U (en) * | 2017-07-21 | 2018-02-02 | 临沂大学 | A kind of tumor cell culture case for being easy to take |
-
2018
- 2018-06-22 CN CN201810648319.3A patent/CN108753614A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013129558A1 (en) * | 2012-02-29 | 2013-09-06 | 株式会社ジェイテック | Cell culture device having culture medium replacement function |
| CN205528837U (en) * | 2016-04-14 | 2016-08-31 | 中国人民解放军第四军医大学 | Antitumor cell culture device for immunity |
| CN206956060U (en) * | 2017-07-21 | 2018-02-02 | 临沂大学 | A kind of tumor cell culture case for being easy to take |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111423976A (en) * | 2020-04-10 | 2020-07-17 | 太原师范学院 | Aseptic inoculation device of microorganism |
| CN111735908A (en) * | 2020-05-06 | 2020-10-02 | 安徽科技学院 | Device and method for batch identification of wheat salt tolerance |
| CN113583869A (en) * | 2021-07-13 | 2021-11-02 | 杨金山 | Tumor cell culture device convenient to store and take |
| CN117264767A (en) * | 2023-11-10 | 2023-12-22 | 广州维柏生物科技有限公司 | Cell amplification incubator for gene detection |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108753614A (en) | Anti-tumor experiment tumor cell culture device | |
| EP1944359B1 (en) | Shaker for cell culture and shaken culture system in cell culture method | |
| CN205337042U (en) | Agricultural is with automatic incubator of plant | |
| CN106701563A (en) | Full-automatic control multifunctional solid-state fermentation tank | |
| KR20100130657A (en) | High efficiency cultivation apparatus | |
| CN208472105U (en) | Examine microbiological incubator | |
| CN207655044U (en) | A kind of desk-top constant-temperature table | |
| CN107955780A (en) | A kind of medical Incubators for bacteria culture | |
| CN106595270A (en) | Wood dehydration and sterilization device | |
| CN107523496A (en) | A kind of installation for fermenting of comprehensive environmental experiment | |
| KR101446512B1 (en) | Sterilization Incubator having Photosynthesis Culture Function | |
| CN206828515U (en) | A kind of microbial immobilized fermentation reactor | |
| JP2014502512A (en) | Cell culture tank | |
| KR20030095441A (en) | Solid state fermenter of mushroom or microorganism, coupled asceptic packing mechanism and fermentation method | |
| CN203474788U (en) | Food microbial detection kit | |
| CN207918856U (en) | A kind of medical Incubators for bacteria culture | |
| CN207159236U (en) | A kind of cell culture apparatus for strengthening oxygen supply | |
| CN211962638U (en) | A sterilization equipment for yeast powder production | |
| CN209010520U (en) | Adjustable speed constant temperature tissue dissociation device | |
| CN106493141A (en) | A kind of board-washing machine for circulating incubation with wind | |
| TW201127953A (en) | Precisely monitoring equipment for beneficial fungi solid state fermentation | |
| CN112251347B (en) | Biochemical culture apparatus for environmental detection | |
| CN211199229U (en) | Efficient microbial fermentation equipment | |
| CN109136004A (en) | A kind of fermentor | |
| CN213416889U (en) | Partitioned thermal constant-temperature incubator |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20181106 |