CN108750160B - Ampoule bottle sealing method - Google Patents

Ampoule bottle sealing method Download PDF

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Publication number
CN108750160B
CN108750160B CN201810645271.0A CN201810645271A CN108750160B CN 108750160 B CN108750160 B CN 108750160B CN 201810645271 A CN201810645271 A CN 201810645271A CN 108750160 B CN108750160 B CN 108750160B
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China
Prior art keywords
opening
accommodating cavity
accommodating
ampoule
bottle
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CN201810645271.0A
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CN108750160A (en
Inventor
杨雁南
翟志斌
谢雷
沈飞宙
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Semeatech Shanghai Co ltd
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Semeatech Shanghai Co ltd
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Priority to CN201810645271.0A priority Critical patent/CN108750160B/en
Publication of CN108750160A publication Critical patent/CN108750160A/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B7/00Closing containers or receptacles after filling
    • B65B7/16Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
    • B65B7/161Sealing filled ampoules

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Closures For Containers (AREA)

Abstract

The invention provides a sealing method of an ampoule bottle, and relates to the technical field of ampoule bottles. The ampoule bottle comprises a first bottle body and a plug, wherein the first bottle body comprises a first accommodating part and a second accommodating part, the first accommodating part is provided with a first accommodating cavity and a first opening, the second accommodating part is provided with a second accommodating cavity, and the second accommodating cavity is used for accommodating a target sample. The first accommodating part and the second accommodating part are connected and form a second opening, the first accommodating cavity is communicated with the second accommodating cavity, and the first opening is communicated with the first accommodating cavity; the plug is arranged at the second opening and used for separating the first accommodating cavity from the second accommodating cavity, and the first opening is welded and sealed. The ampoule bottle can be used for sealing special chemicals (flame-sensitive, volatile and corrosive chemicals, etc.), highly volatile reagents, gases, etc., and has low cost and simple process.

Description

Ampoule bottle sealing method
Technical Field
The invention relates to the technical field of ampoule bottles, in particular to a sealing method of ampoule bottles.
Background
Ampoule bottles are small sealed containers, typically made of glass materials, for sealing and preserving chemical reagents, medicaments and the like. The ampoule bottle is sealed by adopting a port flame sealing method, namely, the port of the glass bottle is sealed by melting under flame. Ampoule bottles are often used for long-term preservation of small amounts of pharmaceutical and chemical agents due to the special inertness of the glass material and the reliability of flame sealing.
However, for high-volatility liquid, reagents sensitive to flame, corrosive liquid and the like, the port flame sealing operation process is complex, the difficulty is high, and the sealing is generally carried out under the protection of inert gas or the condition of low-temperature cooling. Compared with the common melt sealing process, the process has the advantages of high cost, more difficult operation and complexity. If a gas sample is to be packaged, it cannot be quantitatively packaged unless it is liquefied at a low temperature.
Therefore, developing an ampoule bottle that can effectively solve the above problems is a technical problem that needs to be solved urgently at present.
Disclosure of Invention
The invention aims to provide an ampoule bottle which can be used for sealing special chemicals (flame-sensitive, volatile and corrosive chemicals, etc.), high-volatility reagents, gases and the like, and has low cost and simple process.
Another object of the present invention is to provide a method for sealing an ampoule bottle, which is convenient to operate and low in cost.
The invention solves the technical problems by adopting the following technical scheme:
the invention provides an ampoule bottle, which comprises a first bottle body and a plug, wherein the first bottle body comprises a first accommodating part and a second accommodating part, the first accommodating part is provided with a first accommodating cavity and a first opening, the second accommodating part is provided with a second accommodating cavity, and the second accommodating cavity is used for accommodating a target sample;
the first accommodating part is connected with the second accommodating part, a second opening is formed, the first accommodating cavity is communicated with the second accommodating cavity, and the first opening is communicated with the first accommodating cavity; the plug is arranged in the second opening and used for separating the first accommodating cavity from the second accommodating cavity, and the first opening is welded and sealed.
Further, the inner wall of the second opening is smooth, and the plug is made of soft or elastic material.
Further, a layer of frosted glass surface is arranged on the inner wall of the second opening, and the plug is a frosted glass piston.
Further, the diameter of the second opening is smaller than the diameter of the first accommodating cavity and smaller than the diameter of the second accommodating cavity.
Further, the target sample is a flame-sensitive chemical, a volatile chemical, a corrosive chemical, a highly volatile reagent, or a gas.
Further, the volume of the second accommodating cavity is larger than the volume of the first accommodating cavity.
Further, the first bottle is made of a glass material.
The invention provides another ampoule bottle which comprises a first bottle body, a second bottle body and a plug, wherein the first bottle body is provided with a first accommodating cavity and a first opening which are communicated with each other, the second bottle body is provided with a second accommodating cavity and a second opening which are communicated with each other, and the second accommodating cavity is used for accommodating a target sample; the second bottle body set up in first holding intracavity, first holding chamber with the second holding chamber passes through the second opening intercommunication, the end cap set up in second opening part, and sealed the second opening, first opening butt fusion seals.
Further, the second bottle body is in a strip shape, and the diameter of the second bottle body is smaller than that of the first opening.
The invention provides a sealing method of an ampoule bottle, which adopts the ampoule bottle, wherein the ampoule bottle comprises a first bottle body and a plug, the first bottle body comprises a first accommodating part and a second accommodating part, the first accommodating part is provided with a first accommodating cavity and a first opening, the second accommodating part is provided with a second accommodating cavity, and the second accommodating cavity is used for accommodating a target sample;
the first accommodating part is connected with the second accommodating part, a second opening is formed, the first accommodating cavity is communicated with the second accommodating cavity, and the first opening is communicated with the first accommodating cavity; the plug is arranged in the second opening and used for separating the first accommodating cavity from the second accommodating cavity, and the first opening is welded and sealed.
The ampoule bottle sealing method comprises the following steps:
filling the second accommodation chamber with the target sample; the plug is arranged at the second opening and separates the first accommodating cavity from the second accommodating cavity so as to seal the target sample; welding the first opening.
The embodiment of the invention has the beneficial effects that:
the second opening of the ampoule bottle disclosed by the invention can be sealed through the plug, so that when the second accommodating cavity is used for accommodating target samples such as flame-sensitive chemicals, volatile chemicals, corrosive chemicals and the like, the second accommodating cavity can be temporarily sealed through the plug, and further, the first opening of the first accommodating part can be welded through a welding method, so that the first accommodating cavity and the second accommodating cavity are further sealed.
According to the ampoule bottle sealing method, the ampoule bottle is adopted, the target samples such as the flame-sensitive chemicals, the volatile chemicals and the corrosive chemicals can be arranged in the second accommodating cavity, then the second accommodating cavity is sealed through the plug, and the first opening is further sealed in a welding mode, so that the first accommodating cavity and the second accommodating cavity are further completely sealed, the operation is convenient, and the cost is low.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are needed in the embodiments will be briefly described below, it being understood that the following drawings only illustrate a certain embodiment of the present invention and therefore should not be considered as limiting the scope, and that other related drawings can be obtained according to these drawings without inventive effort for a person skilled in the art.
Fig. 1 is a schematic structural diagram of an ampoule bottle according to a first embodiment of the present invention.
Fig. 2 is a flow chart of a method for sealing an ampoule bottle according to a first embodiment of the present invention.
Fig. 3 is a schematic structural diagram of an ampoule bottle before step S120 of the method for sealing an ampoule bottle according to the first embodiment of the present invention.
Fig. 4 is a schematic structural diagram of an ampoule bottle after step S120 and before step S130 in the ampoule bottle sealing method according to the first embodiment of the present invention.
Fig. 5 is a flow chart of a method of sealing an ampoule in a preferred embodiment.
Fig. 6 is a schematic structural diagram of an ampoule bottle according to a second embodiment of the present invention.
Fig. 7 is a schematic structural diagram of a second body of an ampoule according to a second embodiment of the present invention.
Fig. 8 is a flow chart of a method for sealing an ampoule bottle according to a second embodiment of the present invention.
Icon: 100-ampoule bottle; 101-a first bottle; 110-a first receiving portion; 112-a first receiving chamber; 113-a first opening; 120-a second receiving portion; 121-a second receiving chamber; 122-a second opening; 102-plug; 200-ampoule bottle; 210-a first bottle; 211-a first accommodation chamber; 212-a first opening; 220-a second bottle; 221-a second accommodation chamber; 223-a second opening; 230-plug.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments of the present invention. The components of the embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the invention, as presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further definition or explanation thereof is necessary in the following figures.
In the description of the present invention, it should be noted that, the azimuth or positional relationship indicated by the term "upper" or the like is based on the azimuth or positional relationship shown in the drawings, or the azimuth or positional relationship that is commonly put when the inventive product is used, only for convenience of describing the present invention and simplifying the description, but does not indicate or imply that the apparatus or element to be referred to must have a specific azimuth, be configured and operated in a specific azimuth, and thus should not be construed as limiting the present invention.
Furthermore, the terms "first," "second," "third," and "fourth," etc. are used merely to distinguish between descriptions and should not be construed as indicating or implying relative importance.
In the description of the present invention, it should also be noted that, unless specified and limited otherwise, the terms "disposed" and "connected" are to be construed broadly, and for example, "connected" may be a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention will be understood in specific cases by those of ordinary skill in the art.
An embodiment of the present invention will be described in detail below with reference to the accompanying drawings, and features of the following examples may be combined with each other without conflict.
First embodiment
Fig. 1 is a schematic diagram of an ampoule bottle 100 according to the present embodiment. Referring to fig. 1, the present embodiment discloses an ampoule bottle 100, which includes a first bottle body 101 and a stopper 102. The stopper 102 is disposed in the first bottle 101, and the first bottle 101 may be used to hold a target sample, for example, a gaseous sample, a liquid sample, and seal a specific chemical (for example, a flame-sensitive chemical, a volatile chemical, a corrosive chemical, etc.), a highly volatile reagent, a gas, etc.
The first bottle 101 includes a first accommodating portion 110 and a second accommodating portion 120, wherein the first accommodating portion 110 has a first accommodating cavity 112 and has a first opening 113, the second accommodating portion 120 has a second accommodating cavity 121, and the second accommodating cavity 121 is used for accommodating a target sample.
The first accommodating portion 110 is connected with the second accommodating portion 120, and forms a second opening 122, the first accommodating cavity 112 is communicated with the second accommodating cavity 121, and the first opening 113 is communicated with the first accommodating cavity 112.
The plug 102 is disposed in the second opening 122 and serves to partition the first receiving chamber 112 and the second receiving chamber 121, thereby sealing the target specimen received in the second receiving chamber 121, and the first opening 113 is fusion-sealed, thereby further sealing the target specimen.
It will be appreciated that the sealing of the second opening 122 is a non-flame process with the plug 102 being plugged, and that sealing of flame-sensitive chemical or gas samples under conventional conditions can be readily accomplished, if only such a seal is used for a limited period of time, and the first opening 113 is further sealed by means of a frit seal, long-term storage of the target sample can be ensured.
In this embodiment, to facilitate the sealing engagement between the plug 102 and the second opening 122, the diameter of the second opening 122 is smaller than the diameter of the first accommodating cavity 112 and smaller than the diameter of the second accommodating cavity 121.
In order to store as many target samples as possible, in this embodiment, the volume of the second accommodation chamber 121 is larger than the volume of the first accommodation chamber 112.
As an embodiment, the first bottle 101 is made of glass material, and the first bayonet is sealed by flame sealing.
It should be noted that, in order to ensure good tightness, the plug 102 may be made of different materials according to the internal structure of the second opening 122. For example, if the inner wall of the second opening 122 is smooth, the plug 102 may be made of a soft or elastic material. If the inner wall of the second opening 122 is provided with a frosted glass surface, the plug 102 may be selected as a frosted glass piston.
Fig. 2 is a flow chart of a method for sealing an ampoule bottle according to the present embodiment. Fig. 3 is a schematic structural diagram of the ampoule bottle 100 before step S120 of the ampoule bottle sealing method according to the present embodiment. Fig. 4 is a schematic structural diagram of the ampoule bottle 100 after step S120 and before step S130 in the ampoule bottle sealing method according to the present embodiment. Referring to fig. 2-4, when the ampoule bottle 100 of the present embodiment is used for containing a target reagent, the sealing method of the ampoule bottle includes the following steps:
step S110: the second accommodation chamber 121 is filled with the target sample.
The target sample may be a gaseous, liquid or solid sample.
Step S120: the plug 102 is disposed in the second opening 122 and separates the first accommodating cavity 112 from the second accommodating cavity 121.
It will be appreciated that this step enables a preliminary sealing of the target specimen.
Step S130: the first opening 113 is welded.
It will be appreciated that when the target sample is a flammable highly volatile liquid or a flammable, explosive gas, the process proceeds to step S110: when the second accommodating chamber 121 is filled with the target sample, the sample passes through the first accommodating chamber 112, and the residual target sample is present in the first accommodating chamber 112, so that the step S130 is performed: when the first opening 113 is welded, safety hazards such as explosion are easily caused.
Fig. 5 is a flow chart of a method of sealing an ampoule in a preferred embodiment. Referring to fig. 5, when the target sample is a flammable and highly volatile liquid or a flammable and explosive gas, the ampoule sealing method further includes the following steps between step S120 and step S130:
step S140: the target reagent remaining in the first accommodation chamber 112 is replaced with an inert gas.
It will be appreciated that ampoule 100 of this construction is simple in construction, low in cost, and simple in process.
It will be appreciated that the ampoule bottle 100 disclosed in this embodiment has the second opening 122 capable of being sealed by the plug 102, so that when the second accommodating cavity 121 is used for accommodating a target sample such as a flame-sensitive chemical, a volatile chemical, and a corrosive chemical, the second accommodating cavity 121 can be temporarily sealed by the plug 102, and further, the first opening 113 of the first accommodating portion 110 can be welded by a welding method, so that the first accommodating cavity 112 and the second accommodating cavity 121 can be further sealed.
According to the ampoule bottle sealing method disclosed by the embodiment, the ampoule bottle 100 disclosed by the embodiment is adopted, target samples such as flame-sensitive chemicals, volatile chemicals and corrosive chemicals can be firstly arranged in the second accommodating cavity 121, then the second accommodating cavity 121 is sealed through the plug 102, and the first opening 113 is further sealed through a welding mode, so that the first accommodating cavity 112 and the second accommodating cavity 121 are further completely sealed, the operation is convenient, and the cost is low.
Second embodiment
Fig. 6 is a schematic structural diagram of an ampoule 200 according to the present embodiment. Referring to fig. 6, another ampoule 200 is provided in this embodiment, which includes a first bottle 210, a second bottle 220, and a stopper 230.
Wherein, the first bottle 210 and the second bottle 220 are made of glass material.
The first bottle 210 has a first accommodation chamber 211 and a first opening 212 communicating with each other, and the second bottle 220 has a second accommodation chamber 221 and a second opening 223 communicating with each other, the second accommodation chamber 221 being for accommodating a target sample.
The second bottle 220 is disposed in the first accommodating cavity 211, the first accommodating cavity 211 and the second accommodating cavity 221 are communicated through the second opening 223, the plug 230 is disposed at the second opening 223, the second opening 223 is sealed, and the first opening 212 is sealed by welding.
Fig. 7 is a schematic structural diagram of a second bottle 220 of the ampoule 200 according to the present embodiment. Referring to fig. 7, in the present embodiment, the second bottle 220 is elongated, and the diameter of the second bottle 220 is smaller than that of the first opening 212.
Fig. 8 is a flow chart of a method for sealing an ampoule 200 according to the present embodiment. Referring to fig. 6 and 8 in combination, the ampoule 200 with this structure can also realize two seals, has a good sealing effect, and can adapt to target samples with different chemical properties. The method for sealing the ampoule 200 of this structure includes the steps of:
step S210: the second accommodation chamber 221 is filled with the target sample.
It should be noted that the target sample may be a gaseous or solid sample.
Step S220: the stopper 230 is disposed at the second opening 223, and seals the second opening 223.
It will be appreciated that this step enables a preliminary sealing of the target specimen.
Step S230: the second bottle 220 is disposed in the first accommodating chamber 211.
Step S240: the first opening 212 is welded.
It will be appreciated that the ampoule 200 disclosed in this embodiment has the second opening 223 capable of being sealed by the plug 230, so that when the second accommodating cavity 221 is used for accommodating a target sample such as a flame-sensitive chemical, a volatile chemical, and a corrosive chemical, the second accommodating cavity 221 can be temporarily sealed by the plug 230, and further, the first opening 212 can be welded by a welding method, so that the first accommodating cavity 211 and the second accommodating cavity 221 can be further sealed.
According to the ampoule bottle sealing method provided by the embodiment, the ampoule bottle 200 provided by the embodiment can be used for sealing the second accommodating cavity 221 through the plug 230 after the target samples such as flame-sensitive chemicals, volatile chemicals and corrosive chemicals are arranged in the second accommodating cavity 221, and further sealing the first opening 212 through a welding mode, so that the first accommodating cavity 211 and the second accommodating cavity 221 are further completely sealed, the operation is convenient, and the cost is low.
The above description is only of the preferred embodiments of the present invention and is not intended to limit the present invention, but various modifications and variations can be made to the present invention by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (8)

1. A sealing method of ampoule bottle is characterized in that,
the ampoule bottle comprises a first bottle body and a plug, wherein the first bottle body comprises a first accommodating part and a second accommodating part, the first accommodating part is wide in upper part and narrow in lower part, is provided with a first accommodating cavity, is provided with a first opening, and is provided with a second accommodating cavity for accommodating a target sample;
the first accommodating part is connected with the second accommodating part, a second opening is formed, the first accommodating cavity is communicated with the second accommodating cavity, and the first opening is communicated with the first accommodating cavity; the plug is arranged at the second opening and used for separating the first accommodating cavity from the second accommodating cavity, and the first opening is welded and sealed;
the ampoule bottle is used for sealing and storing flame-sensitive chemicals, volatile chemicals, corrosive chemicals, high-volatility reagents or gases;
the ampoule bottle sealing method comprises the following steps:
filling the second accommodation chamber with the target sample; the plug is arranged at the second opening and separates the first accommodating cavity from the second accommodating cavity so as to seal the target sample; welding the first opening.
2. The method of sealing an ampoule of claim 1, wherein the inner wall of the second opening is smooth and the stopper is made of a soft or elastic material.
3. The method of sealing an ampoule of claim 1, wherein the inner wall of the second opening is provided with a frosted glass surface, and the stopper is a frosted glass piston.
4. The method of sealing an ampoule of claim 1, wherein the diameter of the second opening is smaller than the diameter of the first receiving chamber and smaller than the diameter of the second receiving chamber.
5. The method of sealing an ampoule of claim 1, wherein the volume of the second receiving chamber is greater than the volume of the first receiving chamber.
6. The method of sealing an ampoule of claim 1, wherein the first body is made of a glass material.
7. A sealing method of ampoule bottle is characterized in that,
the ampoule bottle comprises a first bottle body, a second bottle body and a plug, wherein the first bottle body is provided with a first accommodating cavity and a first opening which are communicated with each other, the second bottle body is provided with a second accommodating cavity and a second opening which are communicated with each other, and the second accommodating cavity is used for accommodating a target sample;
the second bottle body is arranged in the first accommodating cavity, the first accommodating cavity is communicated with the second accommodating cavity through the second opening, the plug is arranged at the second opening and seals the second opening, and the first opening is welded and sealed;
the ampoule bottle sealing method comprises the following steps:
filling the second accommodation chamber with the target sample; the plug is arranged at the second opening and separates the first accommodating cavity from the second accommodating cavity so as to seal the target sample; welding the first opening.
8. The method of sealing an ampoule of claim 7, wherein the second body is elongated and has a diameter smaller than a diameter of the first opening.
CN201810645271.0A 2018-06-21 2018-06-21 Ampoule bottle sealing method Active CN108750160B (en)

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Application Number Priority Date Filing Date Title
CN201810645271.0A CN108750160B (en) 2018-06-21 2018-06-21 Ampoule bottle sealing method

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CN108750160A CN108750160A (en) 2018-11-06
CN108750160B true CN108750160B (en) 2023-07-25

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Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0524078Y2 (en) * 1987-03-11 1993-06-18
CN201082251Y (en) * 2007-09-29 2008-07-09 贺兰霞 Ampule bottle
CN205034562U (en) * 2015-10-19 2016-02-17 崔兆臣 Function water beverage bottle with mix solid constituent device
CN205257955U (en) * 2015-10-20 2016-05-25 上海市闸北区宝山路街道社区卫生服务中心 Ampoule bottle breaker
CN205328579U (en) * 2015-12-21 2016-06-22 成都普思生物科技股份有限公司 Accommodate device
CN108001801A (en) * 2017-11-15 2018-05-08 盐城星辰包装材料有限公司 A kind of polyester bottles of anti-leak
CN208325717U (en) * 2018-06-21 2019-01-04 盛密科技(上海)有限公司 Ampoule bottle

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